Dr Marco Cantini

  • Lecturer in Medical Applications of Engineering Materials (Biomedical Engineering)

telephone: 01413305242
email: Marco.Cantini@glasgow.ac.uk

Advanced Research Centre (ARC), 11 Chapel Lane, Glasgow, G11 6EW

Import to contacts

ORCID iDhttps://orcid.org/0000-0003-0326-1508

Biography

I am a Lecturer in the Biomedical Engineering Research Division of the James Watt School of Engineering at the University of Glasgow.

In 2004 I received my Bachelor and in 2006 my Master degree in Biomedical Engineering from Politecnico di Milano and Politecnico di Torino in Italy, with full marks and honours. I then graduated from the school for young talents Alta Scuola Politecnica in 2007.

Between 2007 and 2010 I pursued a PhD in Biomedical and Biomechanical Engineering through a joint PhD program (Scuola Interpolitecnica) of the three Italian Technical Universities. I then held post-doctoral researcher positions at the Universitat Politècnica de València and at the Institute for Bioengineering of Catalonia in Spain, focussing my interest on the modulation of cell-protein-material interactions to control cell fate.

In 2013, I moved to the University of Glasgow, where I have been working on material-based strategies to engineer tissue repair and regeneration as a Research Associate in the Microenvironments for Medicine group led by Professor Manuel Salmeron-Sanchez.

In 2018, I was awarded a UKRI Rutherford Fund Fellowship, granted by the MRC in alignment with the UK Regenerative Medicine Platform (UKRMP) initiative.

Research interests

My work, based at the Advanced Research Centre of the University of Glasgow, is carried out within the Centre for the Cellular Microenvironment, a cross-college multidisciplinary initiative of the University.

My current research seeks to engineer microenvironments, based on dynamic biointerfaces and viscoelastic hydrogels, to study cell response to viscosity and viscoelasticity. Besides facilitating our understanding of the mechanotransductive mechanisms involved in the cell's interpretation of these mechanical cues, this work is instructing the design of advanced smart materials for the regulation of stem cell fate, for example for their chondrogenic differentiation for cartilage repair, or as in vitro models of healthy or pathological tissues, for example in cancer research.

My general research interests include the design of advanced materials that simulate the spatio-temporal cues of the extracellular matrix in both physiological and pathological conditions, for applications in regenerative medicine, drug testing and understanding of disease mechanisms. I'm also interested in protein adsorption at the cell-material interface, surface modification to control cell adhesion and differentiation, and atomic force microscopy and spectroscopy.

Keywords: biomaterials, viscoelasticity, mechanobiology, mechanotransduction, regenerative medicine

Publications

Selected publications

Walker, M. , Pringle, E. W., Ciccone, G., Oliver Cervello, L., Tassieri, M. , Gourdon, D. and Cantini, M. (2024) Mind the viscous modulus: the mechanotransductive response to the viscous nature of isoelastic matrices regulates stem cell chondrogenesis. Advanced Healthcare Materials, 13(9), 2302571. (doi: 10.1002/adhm.202302571) (PMID:38014647)

Sprott, M. R. , Gallego-Ferrer, G., Dalby, M. J. , Salmeron-Sanchez, M. and Cantini, M. (2019) Functionalisation of PLLA with polymer brushes to trigger the assembly of fibronectin into nanonetworks. Advanced Healthcare Materials, 8(3), 1801469. (doi: 10.1002/adhm.201801469) (PMID:30609243)

Bennett, M., Cantini, M. , Reboud, J. , Cooper, J. M. , Roca-Cusachs, P. and Salmeron-Sanchez, M. (2018) Molecular clutch drives cell response to surface viscosity. Proceedings of the National Academy of Sciences of the United States of America, 115(6), pp. 1192-1197. (doi: 10.1073/pnas.1710653115) (PMID:29358406)

Ngandu Mpoyi, E., Cantini, M. , Reynolds, P. M. , Gadegaard, N. , Dalby, M. J. and Salmerón-Sánchez, M. (2016) Protein adsorption as a key mediator in the nanotopographical control of cell behavior. ACS Nano, 10(7), pp. 6638-6647. (doi: 10.1021/acsnano.6b01649) (PMID:27391047) (PMCID:PMC4980054)

All publications

List by: Type | Date

Jump to: 2024 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 | 2013 | 2012 | 2009 | 2008 | 2007
Number of items: 43.

2024

Walker, M. , Gourdon, D. and Cantini, M. (2024) Beyond static models: Mechanically dynamic matrices reveal new insights into cancer and fibrosis progression. Current Opinion in Biomedical Engineering, (Accepted for Publication)

Barcelona-Estaje, E., Oliva, M. A.G., Cunniffe, F., Rodrigo-Navarro, A. , Genever, P., Dalby, M. J. , Roca-Cusachs, P., Cantini, M. and Salmeron-Sanchez, M. (2024) N-cadherin crosstalk with integrin weakens the molecular clutch in response to surface viscosity. Nature Communications, 15, 8824. (doi: 10.1038/s41467-024-53107-6) (PMID:39394209)

McNeilly, S. et al. (2024) Collagen IV deficiency causes hypertrophic remodeling and endothelium-dependent hyperpolarization in small vessel disease with intracerebral hemorrhage. EBioMedicine, 107, 105315. (doi: 10.1016/j.ebiom.2024.105315) (PMID:39216230)

Schofield, C., Sarrigiannidis, S., Moran-Horowich, A., Jackson, E., Rodrigo-Navarro, A. , Van Agtmael, T. , Cantini, M. , Dalby, M. J. and Salmeron-Sanchez, M. (2024) An in vitro model of the blood-brain barrier for the investigation and isolation of the key drivers of barriergenesis. Advanced Healthcare Materials, (doi: 10.1002/adhm.202303777) (PMID:39101628) (Early Online Publication)

Walker, M. , Pringle, E. W., Ciccone, G., Oliver Cervello, L., Tassieri, M. , Gourdon, D. and Cantini, M. (2024) Mind the viscous modulus: the mechanotransductive response to the viscous nature of isoelastic matrices regulates stem cell chondrogenesis. Advanced Healthcare Materials, 13(9), 2302571. (doi: 10.1002/adhm.202302571) (PMID:38014647)

2022

Asadishekari, M., Mpoyi, E. N., Li, Y., Eslami, J., Walker, M. , Cantini, M. and Gourdon, D. (2022) Three-dimensional tunable fibronectin-collagen platforms for control of cell adhesion and matrix deposition. Frontiers in Physics, 10, 806554. (doi: 10.3389/fphy.2022.806554)

2021

McDowall, D., Walker, M. , Vassalli, M. , Cantini, M. , Khunti, N., Edwards-Gayle, C. J. C., Cowieson, N. and Adams, D. J. (2021) Controlling the formation and alignment of low molecular weight gel ‘noodles’. Chemical Communications, 57(70), pp. 8782-8785. (doi: 10.1039/D1CC03378F) (PMID:34378594)

Witte, K., Luo, J., Walker, M. , Cantini, M. , Seib, F.P. and Salmeron-Sanchez, M. (2021) Bioinspired and bioinstructive surfaces to control mesenchymal stem cells. In: Azevedo, H. S., Mano, J. F. and Borges, J. (eds.) Soft Matter for Biomedical Applications. Series: Soft matter series (13). Royal Society of Chemistry: Cambridge, pp. 301-325. ISBN 9781788017572 (doi: 10.1039/9781839161124-00301)

Barcelona Estaje, E., Dalby, M. J. , Cantini, M. and Salmeron-Sanchez, M. (2021) You talking to me? Cadherin and integrin crosstalk in biomaterials design. Advanced Healthcare Materials, 10(6), 2002048. (doi: 10.1002/adhm.202002048) (PMID:33586353)

Walker, M. , Luo, J., Pringle, E. W. and Cantini, M. (2021) ChondroGELesis: hydrogels to harness the chondrogenic potential of stem cells. Materials Science and Engineering C: Materials for Biological Applications, 121, 111822. (doi: 10.1016/j.msec.2020.111822) (PMID:33579465)

2020

Ngandu Mpoyi, E. et al. (2020) Material-driven fibronectin assembly rescues matrix defects due to mutations in collagen IV in fibroblasts. Biomaterials, 252, 120090. (doi: 10.1016/j.biomaterials.2020.120090) (PMID:32413593)

Cantini, M. , Donnelly, H. , Dalby, M. J. and Salmeron-Sanchez, M. (2020) The plot thickens: the emerging role of matrix viscosity in cell mechanotransduction. Advanced Healthcare Materials, 9(8), 1901259. (doi: 10.1002/adhm.201901259) (PMID:31815372)

Nosalski, R. et al. (2020) T cell-derived miRNA-214 mediates perivascular fibrosis in hypertension. Circulation Research, 126, pp. 988-1003. (doi: 10.1161/CIRCRESAHA.119.315428) (PMID:32065054) (PMCID:PMC7147427)

Papalazarou, V., Zhang, T., Paul, N. R., Juin, A., Cantini, M. , Maddocks, O. D.K. , Salmeron-Sanchez, M. and Machesky, L. (2020) The creatine-phosphagen system is mechanoresponsive in pancreatic adenocarcinoma and fuels invasion and metastasis. Nature Metabolism, 2(1), pp. 62-80. (doi: 10.1038/s42255-019-0159-z) (PMID:32694686)

2019

Sprott, M. R. , Gallego-Ferrer, G., Dalby, M. J. , Salmeron-Sanchez, M. and Cantini, M. (2019) Functionalisation of PLLA with polymer brushes to trigger the assembly of fibronectin into nanonetworks. Advanced Healthcare Materials, 8(3), 1801469. (doi: 10.1002/adhm.201801469) (PMID:30609243)

Cheng, Z. A. et al. (2019) Nanoscale coatings for ultralow dose BMP‐2‐driven regeneration of critical‐sized bone defects. Advanced Science, 6(2), 1800361. (doi: 10.1002/advs.201800361) (PMID:30693176) (PMCID:PMC6343071)

Re, F. et al. (2019) 3D gelatin-chitosan hybrid hydrogels combined with human platelet lysate highly support human mesenchymal stem cell proliferation and osteogenic differentiation. Journal of Tissue Engineering, 10, pp. 1-16. (doi: 10.1177/2041731419845852) (PMID:31105928) (PMCID:PMC6507314)

2018

Gonzalez Garcia, C., Cantini, M. , Ballester-Beltran, J., Altankov, G. and Salmeron-Sanchez, M. (2018) The strength of the protein-material interaction determines cell fate. Acta Biomaterialia, 77, pp. 74-84. (doi: 10.1016/j.actbio.2018.07.016) (PMID:30006313)

Bennett, M., Cantini, M. , Reboud, J. , Cooper, J. M. , Roca-Cusachs, P. and Salmeron-Sanchez, M. (2018) Molecular clutch drives cell response to surface viscosity. Proceedings of the National Academy of Sciences of the United States of America, 115(6), pp. 1192-1197. (doi: 10.1073/pnas.1710653115) (PMID:29358406)

2017

Cantini, M. , Gomide, K., Moulisova, V. , González-García, C. and Salmerón-Sánchez, M. (2017) Vitronectin as a micromanager of cell response in material-driven fibronectin nanonetworks. Advanced Biosystems, 1(9), 1700047. (doi: 10.1002/adbi.201700047) (PMID:29497701) (PMCID:PMC5822048)

Grigoriou, E. , Cantini, M. , Dalby, M.J. , Petersen, A. and Salmeron-Sanchez, M. (2017) Cell migration on material-driven fibronectin microenvironments. Biomaterials Science, 5(7), 1326. (doi: 10.1039/C7BM00333A) (PMID:28612879) (PMCID:PMC5858633)

Moulisová, V. , Gonzalez-Garcia, C., Cantini, M. , Rodrigo-Navarro, A. , Weaver, J., Costell, M., Sabater i Serra, R., Dalby, M. J. , García, A. J. and Salmerón-Sánchez, M. (2017) Engineered microenvironments for synergistic VEGF - integrin signalling during vascularization. Biomaterials, 126, pp. 61-74. (doi: 10.1016/j.biomaterials.2017.02.024) (PMID:28279265) (PMCID:PMC5354119)

Gugutkov, D., Gustavsson, J., Cantini, M. , Salmeron-Sanchez, M. and Altankov, G. (2017) Electrospun fibrinogen-PLA nanofibres for vascular tissue engineering. Journal of Tissue Engineering and Regenerative Medicine, 11(10), pp. 2774-2784. (doi: 10.1002/term.2172) (PMID:27238477)

2016

Llopis-Hernández, V. , Cantini, M. , González-García, C., Cheng, Z. A., Yang, J., Tsimbouri, P. M. , García, A. J., Dalby, M. J. and Salmerón-Sánchez, M. (2016) Material-driven fibronectin assembly for high-efficiency presentation of growth factors. Science Advances, 2(8), e1600188. (doi: 10.1126/sciadv.1600188) (PMID:27574702) (PMCID:PMC5001810)

Ngandu Mpoyi, E., Cantini, M. , Reynolds, P. M. , Gadegaard, N. , Dalby, M. J. and Salmerón-Sánchez, M. (2016) Protein adsorption as a key mediator in the nanotopographical control of cell behavior. ACS Nano, 10(7), pp. 6638-6647. (doi: 10.1021/acsnano.6b01649) (PMID:27391047) (PMCID:PMC4980054)

Bathawab, F., Bennett, M., Cantini, M. , Reboud, J. , Dalby, M. and Salmeron-Sanchez, M. (2016) Lateral chain length in polyalkyl acrylates determines the mobility of fibronectin at the cell/material interface. Langmuir, 32(3), pp. 800-809. (doi: 10.1021/acs.langmuir.5b03259) (PMID:26715432) (PMCID:PMC4732669)

2015

Marín-Pareja, N., Cantini, M. , Gonzalez-Garcia, C., Salvagni, E., Salmeron-Sanchez, M. and Ginebra, M.-P. (2015) Different organization of type: collagen immobilized on silanized and nonsilanized titanium surfaces affects fibroblast adhesion and fibronectin secretion. ACS Applied Materials and Interfaces, 7(37), 20667. (doi: 10.1021/acsami.5b05420) (PMID:26322620)

Llopis-Hernandez, V., Cantini, M. , González-García, C. and Salmeron-Sanchez, M. (2015) Material-based strategies to engineer fibronectin matrices for regenerative medicine. International Materials Reviews, 60(5), pp. 245-264. (doi: 10.1179/1743280414Y.0000000049)

2014

Vanterpool, F. A., Cantini, M. , Seib, F. P. and Salmerón-Sánchez, M. (2014) A material-based platform to modulate fibronectin activity and focal adhesion assembly. BioResearch Open Access, 3(6), pp. 286-296. (doi: 10.1089/biores.2014.0033)

Rico Tortosa, P., Cantini, M. , Altankov, G. and Salmeron-Sanchez, M. (2014) Matrix protein interactions with synthetic surfaces. In: Pradas, M.M. and Vicent, M.A. (eds.) Polymers in Regenerative Medicine: Biomedical Applications from Nano- to Macro-Structures. Springer, pp. 91-146. ISBN 9780470596388 (doi: 10.1002/9781118356692.ch3)

Hochman-Mendez, C., Cantini, M. , Moratal, D., Salmeron-Sanchez, M. and Coelho-Sampaio, T. (2014) A fractal nature for polymerized laminin. PLoS ONE, 9(10), e109388. (doi: 10.1371/journal.pone.0109388) (PMID:25296244) (PMCID:PMC4190072)

2013

Gonzalez Garcia, C., Cantini, M. , Moratal, D., Altankov, G. and Salmerón-Sánchez, M. (2013) Vitronectin alters fibronectin organization at the cell–material interface. Colloids and Surfaces B: Biointerfaces, 111(1), pp. 618-625. (doi: 10.1016/j.colsurfb.2013.07.016)

Piola, M., Soncini, M., Cantini, M. , Sadr, N., Ferrario, G. and Fiore, G. B. (2013) Design and functional testing of a multichamber perfusion platform for three-dimensional scaffolds. Scientific World Journal, 2013, 123974. (doi: 10.1155/2013/123974) (PMID:24453787) (PMCID:PMC3885203)

Cantini, M. , Sousa, M., Moratal, D., Mano, J. F. and Salmeron-Sanchez, M. (2013) Non-monotonic cell differentiation pattern on extreme wettability gradients. Biomaterials Science, 1(2), pp. 202-212. (doi: 10.1039/c2bm00063f)

2012

Cantini, M. , Gonzalez-Garcia, C., Llopis-Hernandez, V. and Salmerón-Sánchez, M. (2012) Material-driven fibronectin fibrillogenesis. In: Horbett, T., Brash, B. and Norde, N. (eds.) Proteins at Interfaces III State of the Art 2012. Series: ACS symposium series (1120). American Chemical Society: Washington DC, VA, USA, pp. 471-496. (doi: 10.1021/bk-2012-1120.ch022)

Ballester-Beltrán, J., Cantini, M. , Lebourg, M., Rico, P., Moratal, D., García, A.J. and Salmerón-Sánchez, M. (2012) Effect of topological cues on material-driven fibronectin fibrillogenesis and cell differentiation. Journal of Materials Science: Materials in Medicine, 23(1), pp. 195-204. (doi: 10.1007/s10856-011-4532-z)

Cantini, M. , Rico, P., Moratal, D. and Salmerón-Sánchez, M. (2012) Controlled wettability, same chemistry: biological activity of plasma-polymerized coatings. Soft Matter, 8(20), pp. 5575-5584. (doi: 10.1039/c2sm25413a)

Cantini, M. , Rico, P. and Salmerón-Sánchez, M. (2012) Fibronectin fibrillogenesis at the cell-material interface. In: Mano, J.F. (ed.) Biomimetic Approaches for Biomaterials Development. Wiley: Weinham, Germany. ISBN 9783527329168 (doi: 10.1002/9783527652273.ch8)

2009

Cantini, M. , Fiore, G. B., Redaelli, A. and Soncini, M. (2009) CFD-Aided Design of a Dynamic Culture System for the Co-Culture of Adherent and Non-Adherent Cells. ASME 2009 Summer Bioengineering Conference, Lake Tahoe, California, 17-21 June 2009. p. 1067. ISBN 9780791848913 (doi: 10.1115/sbc2009-206431)

Politecnico di Milano (2009) Processo per la sintesi di perfluoroalchileteri. .

2008

Cantini, M. , Fiore, G. B., Redaelli, A. and Soncini, M. (2008) Numerical fluid-dynamic optimization of microchannel-provided porous scaffolds for the co-culture of adherent and non-adherent cells. Tissue Engineering Part A, 15(3), pp. 615-623. (doi: 10.1089/ten.tea.2008.0027)

Cantini, M. , Fiore, G. B., Redaelli, A. and Soncini, M. (2008) Metabolite Transport Inside Channeled Porous Scaffolds for Haematopoietic Stem Cell Culture: A Computational Study. In: ASME 2008 Summer Bioengineering Conference, Marco Island, Florida, 25-29 June 2008, pp. 481-482. ISBN 9780791843215 (doi: 10.1115/SBC2008-192852)

2007

Navarrini, W. et al. (2007) ASP studies on fluorine in biomedicine: two innovative applications. Chimica Oggi = Chemistry Today, 25(3), pp. 48-50.

This list was generated on Wed Dec 11 16:40:45 2024 GMT.
Number of items: 43.

Articles

Walker, M. , Gourdon, D. and Cantini, M. (2024) Beyond static models: Mechanically dynamic matrices reveal new insights into cancer and fibrosis progression. Current Opinion in Biomedical Engineering, (Accepted for Publication)

Barcelona-Estaje, E., Oliva, M. A.G., Cunniffe, F., Rodrigo-Navarro, A. , Genever, P., Dalby, M. J. , Roca-Cusachs, P., Cantini, M. and Salmeron-Sanchez, M. (2024) N-cadherin crosstalk with integrin weakens the molecular clutch in response to surface viscosity. Nature Communications, 15, 8824. (doi: 10.1038/s41467-024-53107-6) (PMID:39394209)

McNeilly, S. et al. (2024) Collagen IV deficiency causes hypertrophic remodeling and endothelium-dependent hyperpolarization in small vessel disease with intracerebral hemorrhage. EBioMedicine, 107, 105315. (doi: 10.1016/j.ebiom.2024.105315) (PMID:39216230)

Schofield, C., Sarrigiannidis, S., Moran-Horowich, A., Jackson, E., Rodrigo-Navarro, A. , Van Agtmael, T. , Cantini, M. , Dalby, M. J. and Salmeron-Sanchez, M. (2024) An in vitro model of the blood-brain barrier for the investigation and isolation of the key drivers of barriergenesis. Advanced Healthcare Materials, (doi: 10.1002/adhm.202303777) (PMID:39101628) (Early Online Publication)

Walker, M. , Pringle, E. W., Ciccone, G., Oliver Cervello, L., Tassieri, M. , Gourdon, D. and Cantini, M. (2024) Mind the viscous modulus: the mechanotransductive response to the viscous nature of isoelastic matrices regulates stem cell chondrogenesis. Advanced Healthcare Materials, 13(9), 2302571. (doi: 10.1002/adhm.202302571) (PMID:38014647)

Asadishekari, M., Mpoyi, E. N., Li, Y., Eslami, J., Walker, M. , Cantini, M. and Gourdon, D. (2022) Three-dimensional tunable fibronectin-collagen platforms for control of cell adhesion and matrix deposition. Frontiers in Physics, 10, 806554. (doi: 10.3389/fphy.2022.806554)

McDowall, D., Walker, M. , Vassalli, M. , Cantini, M. , Khunti, N., Edwards-Gayle, C. J. C., Cowieson, N. and Adams, D. J. (2021) Controlling the formation and alignment of low molecular weight gel ‘noodles’. Chemical Communications, 57(70), pp. 8782-8785. (doi: 10.1039/D1CC03378F) (PMID:34378594)

Barcelona Estaje, E., Dalby, M. J. , Cantini, M. and Salmeron-Sanchez, M. (2021) You talking to me? Cadherin and integrin crosstalk in biomaterials design. Advanced Healthcare Materials, 10(6), 2002048. (doi: 10.1002/adhm.202002048) (PMID:33586353)

Walker, M. , Luo, J., Pringle, E. W. and Cantini, M. (2021) ChondroGELesis: hydrogels to harness the chondrogenic potential of stem cells. Materials Science and Engineering C: Materials for Biological Applications, 121, 111822. (doi: 10.1016/j.msec.2020.111822) (PMID:33579465)

Ngandu Mpoyi, E. et al. (2020) Material-driven fibronectin assembly rescues matrix defects due to mutations in collagen IV in fibroblasts. Biomaterials, 252, 120090. (doi: 10.1016/j.biomaterials.2020.120090) (PMID:32413593)

Cantini, M. , Donnelly, H. , Dalby, M. J. and Salmeron-Sanchez, M. (2020) The plot thickens: the emerging role of matrix viscosity in cell mechanotransduction. Advanced Healthcare Materials, 9(8), 1901259. (doi: 10.1002/adhm.201901259) (PMID:31815372)

Nosalski, R. et al. (2020) T cell-derived miRNA-214 mediates perivascular fibrosis in hypertension. Circulation Research, 126, pp. 988-1003. (doi: 10.1161/CIRCRESAHA.119.315428) (PMID:32065054) (PMCID:PMC7147427)

Papalazarou, V., Zhang, T., Paul, N. R., Juin, A., Cantini, M. , Maddocks, O. D.K. , Salmeron-Sanchez, M. and Machesky, L. (2020) The creatine-phosphagen system is mechanoresponsive in pancreatic adenocarcinoma and fuels invasion and metastasis. Nature Metabolism, 2(1), pp. 62-80. (doi: 10.1038/s42255-019-0159-z) (PMID:32694686)

Sprott, M. R. , Gallego-Ferrer, G., Dalby, M. J. , Salmeron-Sanchez, M. and Cantini, M. (2019) Functionalisation of PLLA with polymer brushes to trigger the assembly of fibronectin into nanonetworks. Advanced Healthcare Materials, 8(3), 1801469. (doi: 10.1002/adhm.201801469) (PMID:30609243)

Cheng, Z. A. et al. (2019) Nanoscale coatings for ultralow dose BMP‐2‐driven regeneration of critical‐sized bone defects. Advanced Science, 6(2), 1800361. (doi: 10.1002/advs.201800361) (PMID:30693176) (PMCID:PMC6343071)

Re, F. et al. (2019) 3D gelatin-chitosan hybrid hydrogels combined with human platelet lysate highly support human mesenchymal stem cell proliferation and osteogenic differentiation. Journal of Tissue Engineering, 10, pp. 1-16. (doi: 10.1177/2041731419845852) (PMID:31105928) (PMCID:PMC6507314)

Gonzalez Garcia, C., Cantini, M. , Ballester-Beltran, J., Altankov, G. and Salmeron-Sanchez, M. (2018) The strength of the protein-material interaction determines cell fate. Acta Biomaterialia, 77, pp. 74-84. (doi: 10.1016/j.actbio.2018.07.016) (PMID:30006313)

Bennett, M., Cantini, M. , Reboud, J. , Cooper, J. M. , Roca-Cusachs, P. and Salmeron-Sanchez, M. (2018) Molecular clutch drives cell response to surface viscosity. Proceedings of the National Academy of Sciences of the United States of America, 115(6), pp. 1192-1197. (doi: 10.1073/pnas.1710653115) (PMID:29358406)

Cantini, M. , Gomide, K., Moulisova, V. , González-García, C. and Salmerón-Sánchez, M. (2017) Vitronectin as a micromanager of cell response in material-driven fibronectin nanonetworks. Advanced Biosystems, 1(9), 1700047. (doi: 10.1002/adbi.201700047) (PMID:29497701) (PMCID:PMC5822048)

Grigoriou, E. , Cantini, M. , Dalby, M.J. , Petersen, A. and Salmeron-Sanchez, M. (2017) Cell migration on material-driven fibronectin microenvironments. Biomaterials Science, 5(7), 1326. (doi: 10.1039/C7BM00333A) (PMID:28612879) (PMCID:PMC5858633)

Moulisová, V. , Gonzalez-Garcia, C., Cantini, M. , Rodrigo-Navarro, A. , Weaver, J., Costell, M., Sabater i Serra, R., Dalby, M. J. , García, A. J. and Salmerón-Sánchez, M. (2017) Engineered microenvironments for synergistic VEGF - integrin signalling during vascularization. Biomaterials, 126, pp. 61-74. (doi: 10.1016/j.biomaterials.2017.02.024) (PMID:28279265) (PMCID:PMC5354119)

Gugutkov, D., Gustavsson, J., Cantini, M. , Salmeron-Sanchez, M. and Altankov, G. (2017) Electrospun fibrinogen-PLA nanofibres for vascular tissue engineering. Journal of Tissue Engineering and Regenerative Medicine, 11(10), pp. 2774-2784. (doi: 10.1002/term.2172) (PMID:27238477)

Llopis-Hernández, V. , Cantini, M. , González-García, C., Cheng, Z. A., Yang, J., Tsimbouri, P. M. , García, A. J., Dalby, M. J. and Salmerón-Sánchez, M. (2016) Material-driven fibronectin assembly for high-efficiency presentation of growth factors. Science Advances, 2(8), e1600188. (doi: 10.1126/sciadv.1600188) (PMID:27574702) (PMCID:PMC5001810)

Ngandu Mpoyi, E., Cantini, M. , Reynolds, P. M. , Gadegaard, N. , Dalby, M. J. and Salmerón-Sánchez, M. (2016) Protein adsorption as a key mediator in the nanotopographical control of cell behavior. ACS Nano, 10(7), pp. 6638-6647. (doi: 10.1021/acsnano.6b01649) (PMID:27391047) (PMCID:PMC4980054)

Bathawab, F., Bennett, M., Cantini, M. , Reboud, J. , Dalby, M. and Salmeron-Sanchez, M. (2016) Lateral chain length in polyalkyl acrylates determines the mobility of fibronectin at the cell/material interface. Langmuir, 32(3), pp. 800-809. (doi: 10.1021/acs.langmuir.5b03259) (PMID:26715432) (PMCID:PMC4732669)

Marín-Pareja, N., Cantini, M. , Gonzalez-Garcia, C., Salvagni, E., Salmeron-Sanchez, M. and Ginebra, M.-P. (2015) Different organization of type: collagen immobilized on silanized and nonsilanized titanium surfaces affects fibroblast adhesion and fibronectin secretion. ACS Applied Materials and Interfaces, 7(37), 20667. (doi: 10.1021/acsami.5b05420) (PMID:26322620)

Llopis-Hernandez, V., Cantini, M. , González-García, C. and Salmeron-Sanchez, M. (2015) Material-based strategies to engineer fibronectin matrices for regenerative medicine. International Materials Reviews, 60(5), pp. 245-264. (doi: 10.1179/1743280414Y.0000000049)

Vanterpool, F. A., Cantini, M. , Seib, F. P. and Salmerón-Sánchez, M. (2014) A material-based platform to modulate fibronectin activity and focal adhesion assembly. BioResearch Open Access, 3(6), pp. 286-296. (doi: 10.1089/biores.2014.0033)

Hochman-Mendez, C., Cantini, M. , Moratal, D., Salmeron-Sanchez, M. and Coelho-Sampaio, T. (2014) A fractal nature for polymerized laminin. PLoS ONE, 9(10), e109388. (doi: 10.1371/journal.pone.0109388) (PMID:25296244) (PMCID:PMC4190072)

Gonzalez Garcia, C., Cantini, M. , Moratal, D., Altankov, G. and Salmerón-Sánchez, M. (2013) Vitronectin alters fibronectin organization at the cell–material interface. Colloids and Surfaces B: Biointerfaces, 111(1), pp. 618-625. (doi: 10.1016/j.colsurfb.2013.07.016)

Piola, M., Soncini, M., Cantini, M. , Sadr, N., Ferrario, G. and Fiore, G. B. (2013) Design and functional testing of a multichamber perfusion platform for three-dimensional scaffolds. Scientific World Journal, 2013, 123974. (doi: 10.1155/2013/123974) (PMID:24453787) (PMCID:PMC3885203)

Cantini, M. , Sousa, M., Moratal, D., Mano, J. F. and Salmeron-Sanchez, M. (2013) Non-monotonic cell differentiation pattern on extreme wettability gradients. Biomaterials Science, 1(2), pp. 202-212. (doi: 10.1039/c2bm00063f)

Ballester-Beltrán, J., Cantini, M. , Lebourg, M., Rico, P., Moratal, D., García, A.J. and Salmerón-Sánchez, M. (2012) Effect of topological cues on material-driven fibronectin fibrillogenesis and cell differentiation. Journal of Materials Science: Materials in Medicine, 23(1), pp. 195-204. (doi: 10.1007/s10856-011-4532-z)

Cantini, M. , Rico, P., Moratal, D. and Salmerón-Sánchez, M. (2012) Controlled wettability, same chemistry: biological activity of plasma-polymerized coatings. Soft Matter, 8(20), pp. 5575-5584. (doi: 10.1039/c2sm25413a)

Cantini, M. , Fiore, G. B., Redaelli, A. and Soncini, M. (2008) Numerical fluid-dynamic optimization of microchannel-provided porous scaffolds for the co-culture of adherent and non-adherent cells. Tissue Engineering Part A, 15(3), pp. 615-623. (doi: 10.1089/ten.tea.2008.0027)

Navarrini, W. et al. (2007) ASP studies on fluorine in biomedicine: two innovative applications. Chimica Oggi = Chemistry Today, 25(3), pp. 48-50.

Book Sections

Witte, K., Luo, J., Walker, M. , Cantini, M. , Seib, F.P. and Salmeron-Sanchez, M. (2021) Bioinspired and bioinstructive surfaces to control mesenchymal stem cells. In: Azevedo, H. S., Mano, J. F. and Borges, J. (eds.) Soft Matter for Biomedical Applications. Series: Soft matter series (13). Royal Society of Chemistry: Cambridge, pp. 301-325. ISBN 9781788017572 (doi: 10.1039/9781839161124-00301)

Rico Tortosa, P., Cantini, M. , Altankov, G. and Salmeron-Sanchez, M. (2014) Matrix protein interactions with synthetic surfaces. In: Pradas, M.M. and Vicent, M.A. (eds.) Polymers in Regenerative Medicine: Biomedical Applications from Nano- to Macro-Structures. Springer, pp. 91-146. ISBN 9780470596388 (doi: 10.1002/9781118356692.ch3)

Cantini, M. , Gonzalez-Garcia, C., Llopis-Hernandez, V. and Salmerón-Sánchez, M. (2012) Material-driven fibronectin fibrillogenesis. In: Horbett, T., Brash, B. and Norde, N. (eds.) Proteins at Interfaces III State of the Art 2012. Series: ACS symposium series (1120). American Chemical Society: Washington DC, VA, USA, pp. 471-496. (doi: 10.1021/bk-2012-1120.ch022)

Cantini, M. , Rico, P. and Salmerón-Sánchez, M. (2012) Fibronectin fibrillogenesis at the cell-material interface. In: Mano, J.F. (ed.) Biomimetic Approaches for Biomaterials Development. Wiley: Weinham, Germany. ISBN 9783527329168 (doi: 10.1002/9783527652273.ch8)

Conference or Workshop Item

Cantini, M. , Fiore, G. B., Redaelli, A. and Soncini, M. (2009) CFD-Aided Design of a Dynamic Culture System for the Co-Culture of Adherent and Non-Adherent Cells. ASME 2009 Summer Bioengineering Conference, Lake Tahoe, California, 17-21 June 2009. p. 1067. ISBN 9780791848913 (doi: 10.1115/sbc2009-206431)

Conference Proceedings

Cantini, M. , Fiore, G. B., Redaelli, A. and Soncini, M. (2008) Metabolite Transport Inside Channeled Porous Scaffolds for Haematopoietic Stem Cell Culture: A Computational Study. In: ASME 2008 Summer Bioengineering Conference, Marco Island, Florida, 25-29 June 2008, pp. 481-482. ISBN 9780791843215 (doi: 10.1115/SBC2008-192852)

Patents

Politecnico di Milano (2009) Processo per la sintesi di perfluoroalchileteri. .

This list was generated on Wed Dec 11 16:40:45 2024 GMT.

Grants

  • The Carnegie Trust for the Universities of Scotland (UK), Research Incentive Grant, Viscoelastic regulation of growth factor activity, RIG013300, 2024-2025, £15k (PI)
  • The Royal Society (UK), Research Grants 2023, Harnessing viscoelasticity for regenerative medicine, RGS/R1/231400, 2023-2024, £70k (PI)
  • Engineering and Physical Sciences Research Council (UK), Standard Grants 2022, Nanovibrational control of chondrogenic differentiation, EP/X013057/1, 2023-2026, £870k (Co-I; PI: Prof. Matthew J Dalby)
  • Medical Research Council (UK), UKRI Innovation/Rutherford Fund Fellowship, Engineered microenvironments to harvest stem cell response to viscosity for cartilage repair, MR/S005412/1, 2018-2022, £600k (PI)
  • Ministero dell’Istruzione, dell’Università e della Ricerca (Italy), Doctoral Scolarship, Design of a dynamic culture system for the in vitro mimicry of the bone marrow microenvironment, 2007-2009, €45k

Supervision

Research Associates:

  • Matthew Walker (Viscoelastic hydrogels for cartilage tissue engineering, 2019-2022)

PhD candidates:

First supervisor:

  • Ziyuan Luo (Mechanotransduction in viscoelastic hydrogels, expected 2027)
  • Finlay Cunniffe (Viscoelasticity in the integrin-growth factor crosstalk, expected 2026)
  • Eonan William Pringle (Engineered viscoelastic hydrogels to investigate the mechanoresponse of mesenchymal stem cells, 2020-2024)

Second supervisor:

  • Angel Canal Alonso (Biomimetical neuromodulation in epilepsy: neuromorphic signal generators and bioactive polymers as a tool to enhance DBS, expected 2027)
  • Zarina Issabekova (Development of tuneable microgels for controlled protein delivery in tissue regeneration, expected 2027)
  • Konstantina Evdokimou (Engineering viscoelastic hydrogels for mimicking the tumour microenvironment and stopping tumour progression, expected 2027)
  • Katherine Cory (Modelling the articular cartilage niche to study osteoarthritis, expected 2027)
  • Astrid Ligema (Pericellular matrix viscoelasticity and chondrocyte mechanosensing: implications for osteoarthritis, expected 2026)
  • Dora Rogkoti (Modelling the bone marrow niche to study and predict tumourigenicity, expected 2025)
  • Giuseppe Ciccone (Interplay between matrix geometry and viscoelasticity, 2020-2024)
  • Eva Barcelona-Estaje (Engineering surface mobility to control stem cell differentiation, 2017-2022)
  • Vassilis Papalazarou (Bioengineering microenvironments for pancreatic cancer cell invasion, 2015-2019)
  • Mark Sprott (Synergistic microenvironments to control stem cell fate, 2015-2019)
  • Mark Bennett (Mobility dependent cellular behaviour on supported lipid bilayers, 2014-2018)
  • Elie Ngandu Mpoyi (Engineering biointerfaces to reveal collagen IV disease mechanisms, 2014-2017)
  • Frankie Vanterpool (Deconstructing the tumour microenvironment: the role of fibronectin, 2013-2017)
  • Eleni Grigoriou (Graded organisation of fibronectin to tune cell behaviour, 2013-2017)
  • Fatma Bathawab (Engineering surface mobility to direct stem cell fate, 2013-2017)

PhD opportunities:

PhD students contacts:

  • Canal Alonso, Angel
    Biomimetical neuromodulation in epilepsy: neuromorphic signal generators and bioactive polymers as a tool to enhance DBS
  • Cunniffe, Finlay
    Viscoelasticity in the integrin-growth factor crosstalk

Teaching

  • Biomechanics 3/M (ENG3084/ENG5287)
  • Biomedical Engineering Skills 3 (ENG3090)
  • Biomedical Engineering Skills 2 (ENG2012)
  • Tissue and Cell Engineering 4Y Option (BIOL4124)