2023

Frei, P., Kitson, P. J., Jones, A. X. and Cronin, L. (2023) Digital design and 3D printing of reactionware for on demand synthesis of high value probes. Digital Discovery, 2(5), pp. 1326-1333. (doi: 10.1039/d3dd00108c)

Salley, D., Manzano, J. S., Kitson, P. J. and Cronin, L. (2023) Robotic modules for the programmable chemputation of molecules and materials. ACS Central Science, 9(8), pp. 1525-1537. (doi: 10.1021/acscentsci.3c00304) (PMID:37637738) (PMCID:PMC10450877)

Wang, H., Manzano, J. S., Kitson, P. J., Mullin, M., Lin, C.-G., Slowing, I. I. and Cronin, L. (2023) Digitizing protocols into single reactors for the one-pot synthesis of nanomaterials. Matter, 6(7), pp. 2383-2394. (doi: 10.1016/j.matt.2023.05.029)

2022

Manzano, J. S., Hou, W., Zalesskiy, S. S., Frei, P., Wang, H., Kitson, P. J. and Cronin, L. (2022) An autonomous portable platform for universal chemical synthesis. Nature Chemistry, 14(11), pp. 1311-1318. (doi: 10.1038/s41557-022-01016-w) (PMID:36202987)

Bubliauskas, A., Blair, D. J., Powell-Davies, H., Kitson, P. J., Burke, M. and Cronin, L. (2022) A practical approach to combine modular reactions and reactionware for the digitization of chemical synthesis. Angewandte Chemie (International Edition), 61(24), e202116108. (doi: 10.1002/anie.202116108) (PMID:35257447)

2021

Hou, W., Bubliauskas, A., Kitson, P. J., Francoia, J.-P., Powell-Davies, H., Parrilla Gutierrez, J. M. , Frei, P., Manzano, J. S. and Cronin, L. (2021) Automatic generation of 3D-printed reactionware for chemical synthesis digitization using ChemSCAD. ACS Central Science, 7(2), pp. 212-218. (doi: 10.1021/acscentsci.0c01354) (PMCID:PMC7908023)

2019

Steiner, S. et al. (2019) Organic synthesis in a modular robotic system driven by a chemical programming language. Science, 363(6423), eaav2211. (doi: 10.1126/science.aav2211) (PMID:30498165)

Zalesskiy, S. S., Kitson, P. J., Frei, P., Bubliauskas, A. and Cronin, L. (2019) 3D designed and printed chemical generators for on demand reagent synthesis. Nature Communications, 10, 5496. (doi: 10.1038/s41467-019-13328-6) (PMID:31792220) (PMCID:PMC6889270)

2018

Lin, C.-G., Zhou, W., Xiong, X.-T., Xuan, W., Kitson, P. J., Long, D.-L. , Chen, W., Song, Y.-F. and Cronin, L. (2018) Digital control of multistep hydrothermal synthesis by using 3D printed reactionware for the synthesis of metal–organic frameworks. Angewandte Chemie (International Edition), 57(51), pp. 16716-16720. (doi: 10.1002/anie.201810095) (PMID:30370977) (PMCID:PMC6391986)

Kitson, P. J., Marie, G., Francoia, J.-P., Zalesskiy, S. S., Sigerson, R. C., Mathieson, J. S. and Cronin, L. (2018) Digitization of multistep organic synthesis in reactionware for on-demand pharmaceuticals. Science, 359(6373), pp. 314-319. (doi: 10.1126/science.aao3466) (PMID:29348235)

2016

Kitson, P. J., Glatzel, S. and Cronin, L. (2016) The digital code driven autonomous synthesis of ibuprofen automated in a 3D-printer-based robot. Beilstein Journal of Organic Chemistry, 12, pp. 2776-2783. (doi: 10.3762/bjoc.12.276) (PMID:28144350) (PMCID:PMC5238580)

Porwol, L., Henson, A. , Kitson, P. J., Long, D. L. and Cronin, L. (2016) On the fly multi-modal observation of ligand synthesis and complexation of Cu complexes in flow with ‘benchtop’ NMR and mass spectrometry. Inorganic Chemistry Frontiers, 3(7), pp. 919-923. (doi: 10.1039/C6QI00079G)

Kitson, P. J., Glatzel, S., Chen, W., Lin, C.-G., Song, Y.-F. and Cronin, L. (2016) 3D printing of versatile reactionware for chemical synthesis. Nature Protocols, 11(5), pp. 920-936. (doi: 10.1038/nprot.2016.041) (PMID:27077333)

Glatzel, S., Hezwani, M., Kitson, P. J., Gromski, P. S., Schürer, S. and Cronin, L. (2016) A portable 3D printer system for the diagnosis and treatment of multidrug-resistant bacteria. Chem, 1(3), pp. 494-504. (doi: 10.1016/j.chempr.2016.08.008)

2014

Kitson, P. J., Marshall, R. J., Long, D. , Forgan, R. S. and Cronin, L. (2014) 3D printed high-throughput hydrothermal reactionware for discovery, optimization, and scale-up. Angewandte Chemie (International Edition), 53(47), pp. 12723-12728. (doi: 10.1002/anie.201402654)

Kitson, P. J., Macdonell, A., Tsuda, S., Zang, H., Long, D.-L. and Cronin, L. (2014) Bringing crystal structures to reality by three-dimensional printing. Crystal Growth and Design, 14(6), pp. 2720-2724. (doi: 10.1021/cg5003012)

Chisholm, G. , Kitson, P. J., Kirkaldy, N. D., Bloor, L. G. and Cronin, L. (2014) 3D printed flow plates for the electrolysis of water: an economic and adaptable approach to device manufacture. Energy and Environmental Science, 7(9), pp. 3026-3032. (doi: 10.1039/C4EE01426J)

2013

Kitson, P. J., Symes, M. D. , Dragone, V. and Cronin, L. (2013) Combining 3D printing and liquid handling to produce user-friendly reactionware for chemical synthesis and purification. Chemical Science, 4(8), pp. 3099-3103. (doi: 10.1039/C3SC51253C)

Dragone, V., Sans, V., Rosnes, M. H., Kitson, P. J. and Cronin, L. (2013) 3D-printed devices for continuous-flow organic chemistry. Beilstein Journal of Organic Chemistry, 9, pp. 951-959. (doi: 10.3762/bjoc.9.109) (PMID:23766811) (PMCID:PMC3678713)

Mathieson, J. S., Rosnes, M. H., Sans, V., Kitson, P. J. and Cronin, L. (2013) Continuous parallel ESI-MS analysis of reactions carried out in a bespoke 3D printed device. Beilstein Journal of Nanotechnology, 4, pp. 285-291. (doi: 10.3762/bjnano.4.31) (PMID:23766951) (PMCID:PMC3678396)

2012

Kitson, P. J., Rosnes, M. H., Sans, V., Dragone, V. and Cronin, L. (2012) Configurable 3D-printed millifluidic and microfluidic ‘lab on a chip’ reactionware devices. Lab on a Chip, 12(18), pp. 3267-3271. (doi: 10.1039/C2LC40761B) (PMID:22875258)

Symes, M.D. , Kitson, P.J., Yan, J., Richmond, C., Cooper, G.J.T. , Bowman, R.W., Vilbrandt, T. and Cronin, L. (2012) Integrated 3D-printed reactionware for chemical synthesis and analysis. Nature Chemistry, 4, pp. 349-354. (doi: 10.1038/nchem.1313)

2011

Cooper, G.J.T. , Kitson, P.J., Winter, R., Zagnoni, M., Long, D.L. and Cronin, L. (2011) Modular redox-active inorganic chemical cells: iCHELLs. Angewandte Chemie (International Edition), 50(44), pp. 10373-10376. (doi: 10.1002/anie.201105068)

Cooper, G.T.J. , Boulay, A.G., Kitson, P.J., Ritchie, C., Richmond, C.J., Thiel, J., Gabb, D., Eadie, R., Long, D.L. and Cronin, L. (2011) Osmotically driven crystal morphogenesis: a general approach to the fabrication of micrometer-scale tubular architectures based on polyoxometalates. Journal of the American Chemical Society, 133(15), pp. 5947-5954. (doi: 10.1021/ja111011j)

Cronin, L. , Kitson, P. and Wilson, C.C. (2011) Process understanding – crystallization. In: Houson, I. (ed.) Process Understanding for Scale-up and Manufacture of Active Ingredients. Wiley. ISBN 9783527637140

2009

Kitson, P. J., Parenty, A. D. C., Richmond, C. J., Long, D. L. and Cronin, L. (2009) A new C-C bond forming annulation reaction leading to pH switchable heterocycles. Chemical Communications(27), pp. 4067-4069. (doi: 10.1039/b905383b)

2008

Kitson, P. J., Song, Y. -F., Gamez, P., de Hoog, P., Long, D. L. , Parenty, A. D. C., Reedijk, J. and Cronin, L. (2008) Metal-mediated transformation of a triazinephenanthridinium ligand leading to a {Pd-5} coordination complex observed crystallographically and by cryospray mass Spectrometry. Inorganic Chemistry, 47(6), pp. 1883-1885. (doi: 10.1021/ic7022192)

Song, Y.F., Kitson, P.J., Long, D.L. , Parenty, A.D.C., Thatcher, R.J. and Cronin, L. (2008) Supramolecular self-assembly and anion-dependence of copper(II) complexes with cationic dihydro-imidazo phenanthridinium (DIP)-containing ligands. CrystEngComm, 10(9), pp. 1243-1251. (doi: 10.1039/b802541j)

Articles

Frei, P., Kitson, P. J., Jones, A. X. and Cronin, L. (2023) Digital design and 3D printing of reactionware for on demand synthesis of high value probes. Digital Discovery, 2(5), pp. 1326-1333. (doi: 10.1039/d3dd00108c)

Salley, D., Manzano, J. S., Kitson, P. J. and Cronin, L. (2023) Robotic modules for the programmable chemputation of molecules and materials. ACS Central Science, 9(8), pp. 1525-1537. (doi: 10.1021/acscentsci.3c00304) (PMID:37637738) (PMCID:PMC10450877)

Wang, H., Manzano, J. S., Kitson, P. J., Mullin, M., Lin, C.-G., Slowing, I. I. and Cronin, L. (2023) Digitizing protocols into single reactors for the one-pot synthesis of nanomaterials. Matter, 6(7), pp. 2383-2394. (doi: 10.1016/j.matt.2023.05.029)

Manzano, J. S., Hou, W., Zalesskiy, S. S., Frei, P., Wang, H., Kitson, P. J. and Cronin, L. (2022) An autonomous portable platform for universal chemical synthesis. Nature Chemistry, 14(11), pp. 1311-1318. (doi: 10.1038/s41557-022-01016-w) (PMID:36202987)

Bubliauskas, A., Blair, D. J., Powell-Davies, H., Kitson, P. J., Burke, M. and Cronin, L. (2022) A practical approach to combine modular reactions and reactionware for the digitization of chemical synthesis. Angewandte Chemie (International Edition), 61(24), e202116108. (doi: 10.1002/anie.202116108) (PMID:35257447)

Hou, W., Bubliauskas, A., Kitson, P. J., Francoia, J.-P., Powell-Davies, H., Parrilla Gutierrez, J. M. , Frei, P., Manzano, J. S. and Cronin, L. (2021) Automatic generation of 3D-printed reactionware for chemical synthesis digitization using ChemSCAD. ACS Central Science, 7(2), pp. 212-218. (doi: 10.1021/acscentsci.0c01354) (PMCID:PMC7908023)

Steiner, S. et al. (2019) Organic synthesis in a modular robotic system driven by a chemical programming language. Science, 363(6423), eaav2211. (doi: 10.1126/science.aav2211) (PMID:30498165)

Zalesskiy, S. S., Kitson, P. J., Frei, P., Bubliauskas, A. and Cronin, L. (2019) 3D designed and printed chemical generators for on demand reagent synthesis. Nature Communications, 10, 5496. (doi: 10.1038/s41467-019-13328-6) (PMID:31792220) (PMCID:PMC6889270)

Lin, C.-G., Zhou, W., Xiong, X.-T., Xuan, W., Kitson, P. J., Long, D.-L. , Chen, W., Song, Y.-F. and Cronin, L. (2018) Digital control of multistep hydrothermal synthesis by using 3D printed reactionware for the synthesis of metal–organic frameworks. Angewandte Chemie (International Edition), 57(51), pp. 16716-16720. (doi: 10.1002/anie.201810095) (PMID:30370977) (PMCID:PMC6391986)

Kitson, P. J., Marie, G., Francoia, J.-P., Zalesskiy, S. S., Sigerson, R. C., Mathieson, J. S. and Cronin, L. (2018) Digitization of multistep organic synthesis in reactionware for on-demand pharmaceuticals. Science, 359(6373), pp. 314-319. (doi: 10.1126/science.aao3466) (PMID:29348235)

Kitson, P. J., Glatzel, S. and Cronin, L. (2016) The digital code driven autonomous synthesis of ibuprofen automated in a 3D-printer-based robot. Beilstein Journal of Organic Chemistry, 12, pp. 2776-2783. (doi: 10.3762/bjoc.12.276) (PMID:28144350) (PMCID:PMC5238580)

Porwol, L., Henson, A. , Kitson, P. J., Long, D. L. and Cronin, L. (2016) On the fly multi-modal observation of ligand synthesis and complexation of Cu complexes in flow with ‘benchtop’ NMR and mass spectrometry. Inorganic Chemistry Frontiers, 3(7), pp. 919-923. (doi: 10.1039/C6QI00079G)

Kitson, P. J., Glatzel, S., Chen, W., Lin, C.-G., Song, Y.-F. and Cronin, L. (2016) 3D printing of versatile reactionware for chemical synthesis. Nature Protocols, 11(5), pp. 920-936. (doi: 10.1038/nprot.2016.041) (PMID:27077333)

Glatzel, S., Hezwani, M., Kitson, P. J., Gromski, P. S., Schürer, S. and Cronin, L. (2016) A portable 3D printer system for the diagnosis and treatment of multidrug-resistant bacteria. Chem, 1(3), pp. 494-504. (doi: 10.1016/j.chempr.2016.08.008)

Kitson, P. J., Marshall, R. J., Long, D. , Forgan, R. S. and Cronin, L. (2014) 3D printed high-throughput hydrothermal reactionware for discovery, optimization, and scale-up. Angewandte Chemie (International Edition), 53(47), pp. 12723-12728. (doi: 10.1002/anie.201402654)

Kitson, P. J., Macdonell, A., Tsuda, S., Zang, H., Long, D.-L. and Cronin, L. (2014) Bringing crystal structures to reality by three-dimensional printing. Crystal Growth and Design, 14(6), pp. 2720-2724. (doi: 10.1021/cg5003012)

Chisholm, G. , Kitson, P. J., Kirkaldy, N. D., Bloor, L. G. and Cronin, L. (2014) 3D printed flow plates for the electrolysis of water: an economic and adaptable approach to device manufacture. Energy and Environmental Science, 7(9), pp. 3026-3032. (doi: 10.1039/C4EE01426J)

Kitson, P. J., Symes, M. D. , Dragone, V. and Cronin, L. (2013) Combining 3D printing and liquid handling to produce user-friendly reactionware for chemical synthesis and purification. Chemical Science, 4(8), pp. 3099-3103. (doi: 10.1039/C3SC51253C)

Dragone, V., Sans, V., Rosnes, M. H., Kitson, P. J. and Cronin, L. (2013) 3D-printed devices for continuous-flow organic chemistry. Beilstein Journal of Organic Chemistry, 9, pp. 951-959. (doi: 10.3762/bjoc.9.109) (PMID:23766811) (PMCID:PMC3678713)

Mathieson, J. S., Rosnes, M. H., Sans, V., Kitson, P. J. and Cronin, L. (2013) Continuous parallel ESI-MS analysis of reactions carried out in a bespoke 3D printed device. Beilstein Journal of Nanotechnology, 4, pp. 285-291. (doi: 10.3762/bjnano.4.31) (PMID:23766951) (PMCID:PMC3678396)

Kitson, P. J., Rosnes, M. H., Sans, V., Dragone, V. and Cronin, L. (2012) Configurable 3D-printed millifluidic and microfluidic ‘lab on a chip’ reactionware devices. Lab on a Chip, 12(18), pp. 3267-3271. (doi: 10.1039/C2LC40761B) (PMID:22875258)

Symes, M.D. , Kitson, P.J., Yan, J., Richmond, C., Cooper, G.J.T. , Bowman, R.W., Vilbrandt, T. and Cronin, L. (2012) Integrated 3D-printed reactionware for chemical synthesis and analysis. Nature Chemistry, 4, pp. 349-354. (doi: 10.1038/nchem.1313)

Cooper, G.J.T. , Kitson, P.J., Winter, R., Zagnoni, M., Long, D.L. and Cronin, L. (2011) Modular redox-active inorganic chemical cells: iCHELLs. Angewandte Chemie (International Edition), 50(44), pp. 10373-10376. (doi: 10.1002/anie.201105068)

Cooper, G.T.J. , Boulay, A.G., Kitson, P.J., Ritchie, C., Richmond, C.J., Thiel, J., Gabb, D., Eadie, R., Long, D.L. and Cronin, L. (2011) Osmotically driven crystal morphogenesis: a general approach to the fabrication of micrometer-scale tubular architectures based on polyoxometalates. Journal of the American Chemical Society, 133(15), pp. 5947-5954. (doi: 10.1021/ja111011j)

Kitson, P. J., Parenty, A. D. C., Richmond, C. J., Long, D. L. and Cronin, L. (2009) A new C-C bond forming annulation reaction leading to pH switchable heterocycles. Chemical Communications(27), pp. 4067-4069. (doi: 10.1039/b905383b)

Kitson, P. J., Song, Y. -F., Gamez, P., de Hoog, P., Long, D. L. , Parenty, A. D. C., Reedijk, J. and Cronin, L. (2008) Metal-mediated transformation of a triazinephenanthridinium ligand leading to a {Pd-5} coordination complex observed crystallographically and by cryospray mass Spectrometry. Inorganic Chemistry, 47(6), pp. 1883-1885. (doi: 10.1021/ic7022192)

Song, Y.F., Kitson, P.J., Long, D.L. , Parenty, A.D.C., Thatcher, R.J. and Cronin, L. (2008) Supramolecular self-assembly and anion-dependence of copper(II) complexes with cationic dihydro-imidazo phenanthridinium (DIP)-containing ligands. CrystEngComm, 10(9), pp. 1243-1251. (doi: 10.1039/b802541j)

Book Sections

Cronin, L. , Kitson, P. and Wilson, C.C. (2011) Process understanding – crystallization. In: Houson, I. (ed.) Process Understanding for Scale-up and Manufacture of Active Ingredients. Wiley. ISBN 9783527637140