Dr Christopher Syme
- Translational Research Officer (MVLS Innovation Engagement & Enterprise)
- Honorary Research Fellow (School of Chemistry)
email:
Christopher.Syme@glasgow.ac.uk
School of Chemistry, Joseph Black Building
https://orcid.org/0000-0002-0913-1141Publications
2021
Hajji, M. et al. (2021) A chiral quantum metamaterial for hypersensitive biomolecule detection. ACS Nano, 15(12), pp. 19905-19916. (doi: 10.1021/acsnano.1c07408) (PMID:34846858)
Achour, S., Hosni, Z., Darghouthi, S. and Syme, C. (2021) Assisted dipeptide bond formation: glycine as a case study. Heliyon, 7(6), e07276. (doi: 10.1016/j.heliyon.2021.e07276) (PMID:34195408) (PMCID:PMC8225972)
2020
Walton, F. , Bolling, J., Farrell, A., MacEwen, J., Syme, C. D. , Gonzalez Jimenez, M. , Senn, H. M. , Wilson, C. , Cinque, G. and Wynne, K. (2020) Polyamorphism mirrors polymorphism in the liquid-liquid transition of a molecular liquid. Journal of the American Chemical Society, 142(16), pp. 7591-7597. (doi: 10.1021/jacs.0c01712) (PMID:32249557)
2017
Syme, C. D. , Mosses, J., González-Jiménez, M. , Shebanova, O., Walton, F. and Wynne, K. (2017) Frustration of crystallisation by a liquid–crystal phase. Scientific Reports, 7, 42439. (doi: 10.1038/srep42439) (PMID:28209972) (PMCID:PMC5314399)
2016
Fast, A., Kenison, J. P., Syme, C. D. and Potma, E. O. (2016) Surface-enhanced coherent anti-Stokes Raman imaging of lipids. Applied Optics, 55(22), pp. 5994-6000. (doi: 10.1364/AO.55.005994) (PMID:27505381)
2015
Mosses, J., Syme, C. D. and Wynne, K. (2015) The order parameter of the liquid-liquid transition in a molecular liquid. Journal of Physical Chemistry Letters, 6(1), pp. 38-43. (doi: 10.1021/jz5022763)
2013
Kadodwala, M. , Abdulrahman, N., Syme, C. D. , Jack, C., Barron, L. D., Karimullah, A. and Gadegaard, N. (2013) The origin of off–resonance non-linear optical activity of a gold chiral nanomaterial. Nanoscale, 5(24), pp. 12651-12657. (doi: 10.1039/c3nr04746f)
Reboud, J. , Auchinvole, C., Syme, C.D. , Wilson, R. and Cooper, J.M. (2013) Acoustically controlled enhancement of molecular sensing to assess oxidative stress in cells. Chemical Communications, 49(28), pp. 2918-2920. (doi: 10.1039/C3CC37931K)
2012
Sirimuthu, N.M.S., Syme, C.D. and Cooper, J.M. (2012) Intracellular multiplex detection and imaging of stable chemisorbed labels by SERS spectroscopy. Proceedings of the SPIE: The International Society for Optical Engineering, 8234, 82340F. (doi: 10.1117/12.906419)
Syme, C.D. , Martino, C., Yusvana, R., Sirimuthu, N.M.S. and Cooper, J.M. (2012) Quantitative characterization of individual microdroplets using surface-enhanced resonance Raman scattering spectroscopy. Analytical Chemistry, 84(3), pp. 1491-1495. (doi: 10.1021/ac202705a)
Syme, C.D. , Sirimuthu, N., Martino, C., Yusvana, R. and Cooper, J.M. (2012) Characterization of individual microdroplets by SERRS spectroscopy. Proceedings of the SPIE: The International Society for Optical Engineering, 8234, 82340I. (doi: 10.1117/12.906374)
2011
Sirimuthu, N., Syme, C. and Cooper, J. (2011) Investigation of the stability of labelled nanoparticles for SE(R)RS measurements in cells. Chemical Communications, 47(14), pp. 4099-4101. (doi: 10.1039/c0cc05723a)
2010
Sirimuthu, N.M.S., Syme, C.D. and Cooper, J.M. (2010) Monitoring the uptake and redistribution of metal nanoparticles during cell culture using surface-enhanced raman scattering spectroscopy. Analytical Chemistry, 82(17), pp. 7369-7373. (doi: 10.1021/ac101480t)
Syme, C.D. , Sirimuthu, N.M.S., Faley, S.L. and Cooper, J. (2010) SERS mapping of nanoparticle labels in single cells using a microfluidic chip. Chemical Communications, 46(42), pp. 7921-7923. (doi: 10.1039/C0CC02209H)
2003
Barron, L.D., Blanch, E.W., McColl, I.H., Syme, C.D. , Hecht, L. and Nielsen, K. (2003) Structure and behaviour of proteins, nucleic acids and viruses from vibrational Raman optical activity. Spectroscopy, 17(2-3), pp. 101-126. (doi: 10.1155/2003/787940)
2002
Blanch, E.W., Robinson, D.J., Hecht, L., Syme, C.D. , Nielsen, K. and Barron, L.D. (2002) Solution structures of potato virus X and narcissus mosaic virus from Raman optical activity. Journal of General Virology, 83(1), pp. 241-246.
Syme, C.D. , Blanch, E.W., Holt, C., Jakes, R., Goedert, M., Hecht, L. and Barron, L.D. (2002) A Raman optical activity study of rheomorphism in caseins, synucleins and tau - New insight into the structure and behaviour of natively unfolded proteins. European Journal of Biochemistry, 269(1), pp. 148-156. (doi: 10.1046/j.0014-2956.2001.02633.x)
Blanch, E.W., Hecht, L., Syme, C.D. , Volpetti, V., Lomonossoff, G.P., Nielsen, K. and Barron, L.D. (2002) Molecular structures of viruses from Raman optical activity. Journal of General Virology, 83(10), pp. 2593-2600.
2001
Smyth, E., Syme, C.D. , Blanch, E.W., Hecht, L., Vasak, M. and Barron, L.D. (2001) Solution structure of native proteins with irregular folds from Raman optical activity. Biopolymers, 58(2), pp. 138-151. (doi: 10.1002/1097-0282(200102)58:2<138::AID-BIP30>3.0.CO;2-W)
Articles
Hajji, M. et al. (2021) A chiral quantum metamaterial for hypersensitive biomolecule detection. ACS Nano, 15(12), pp. 19905-19916. (doi: 10.1021/acsnano.1c07408) (PMID:34846858)
Achour, S., Hosni, Z., Darghouthi, S. and Syme, C. (2021) Assisted dipeptide bond formation: glycine as a case study. Heliyon, 7(6), e07276. (doi: 10.1016/j.heliyon.2021.e07276) (PMID:34195408) (PMCID:PMC8225972)
Walton, F. , Bolling, J., Farrell, A., MacEwen, J., Syme, C. D. , Gonzalez Jimenez, M. , Senn, H. M. , Wilson, C. , Cinque, G. and Wynne, K. (2020) Polyamorphism mirrors polymorphism in the liquid-liquid transition of a molecular liquid. Journal of the American Chemical Society, 142(16), pp. 7591-7597. (doi: 10.1021/jacs.0c01712) (PMID:32249557)
Syme, C. D. , Mosses, J., González-Jiménez, M. , Shebanova, O., Walton, F. and Wynne, K. (2017) Frustration of crystallisation by a liquid–crystal phase. Scientific Reports, 7, 42439. (doi: 10.1038/srep42439) (PMID:28209972) (PMCID:PMC5314399)
Fast, A., Kenison, J. P., Syme, C. D. and Potma, E. O. (2016) Surface-enhanced coherent anti-Stokes Raman imaging of lipids. Applied Optics, 55(22), pp. 5994-6000. (doi: 10.1364/AO.55.005994) (PMID:27505381)
Mosses, J., Syme, C. D. and Wynne, K. (2015) The order parameter of the liquid-liquid transition in a molecular liquid. Journal of Physical Chemistry Letters, 6(1), pp. 38-43. (doi: 10.1021/jz5022763)
Kadodwala, M. , Abdulrahman, N., Syme, C. D. , Jack, C., Barron, L. D., Karimullah, A. and Gadegaard, N. (2013) The origin of off–resonance non-linear optical activity of a gold chiral nanomaterial. Nanoscale, 5(24), pp. 12651-12657. (doi: 10.1039/c3nr04746f)
Reboud, J. , Auchinvole, C., Syme, C.D. , Wilson, R. and Cooper, J.M. (2013) Acoustically controlled enhancement of molecular sensing to assess oxidative stress in cells. Chemical Communications, 49(28), pp. 2918-2920. (doi: 10.1039/C3CC37931K)
Sirimuthu, N.M.S., Syme, C.D. and Cooper, J.M. (2012) Intracellular multiplex detection and imaging of stable chemisorbed labels by SERS spectroscopy. Proceedings of the SPIE: The International Society for Optical Engineering, 8234, 82340F. (doi: 10.1117/12.906419)
Syme, C.D. , Martino, C., Yusvana, R., Sirimuthu, N.M.S. and Cooper, J.M. (2012) Quantitative characterization of individual microdroplets using surface-enhanced resonance Raman scattering spectroscopy. Analytical Chemistry, 84(3), pp. 1491-1495. (doi: 10.1021/ac202705a)
Syme, C.D. , Sirimuthu, N., Martino, C., Yusvana, R. and Cooper, J.M. (2012) Characterization of individual microdroplets by SERRS spectroscopy. Proceedings of the SPIE: The International Society for Optical Engineering, 8234, 82340I. (doi: 10.1117/12.906374)
Sirimuthu, N., Syme, C. and Cooper, J. (2011) Investigation of the stability of labelled nanoparticles for SE(R)RS measurements in cells. Chemical Communications, 47(14), pp. 4099-4101. (doi: 10.1039/c0cc05723a)
Sirimuthu, N.M.S., Syme, C.D. and Cooper, J.M. (2010) Monitoring the uptake and redistribution of metal nanoparticles during cell culture using surface-enhanced raman scattering spectroscopy. Analytical Chemistry, 82(17), pp. 7369-7373. (doi: 10.1021/ac101480t)
Syme, C.D. , Sirimuthu, N.M.S., Faley, S.L. and Cooper, J. (2010) SERS mapping of nanoparticle labels in single cells using a microfluidic chip. Chemical Communications, 46(42), pp. 7921-7923. (doi: 10.1039/C0CC02209H)
Barron, L.D., Blanch, E.W., McColl, I.H., Syme, C.D. , Hecht, L. and Nielsen, K. (2003) Structure and behaviour of proteins, nucleic acids and viruses from vibrational Raman optical activity. Spectroscopy, 17(2-3), pp. 101-126. (doi: 10.1155/2003/787940)
Blanch, E.W., Robinson, D.J., Hecht, L., Syme, C.D. , Nielsen, K. and Barron, L.D. (2002) Solution structures of potato virus X and narcissus mosaic virus from Raman optical activity. Journal of General Virology, 83(1), pp. 241-246.
Syme, C.D. , Blanch, E.W., Holt, C., Jakes, R., Goedert, M., Hecht, L. and Barron, L.D. (2002) A Raman optical activity study of rheomorphism in caseins, synucleins and tau - New insight into the structure and behaviour of natively unfolded proteins. European Journal of Biochemistry, 269(1), pp. 148-156. (doi: 10.1046/j.0014-2956.2001.02633.x)
Blanch, E.W., Hecht, L., Syme, C.D. , Volpetti, V., Lomonossoff, G.P., Nielsen, K. and Barron, L.D. (2002) Molecular structures of viruses from Raman optical activity. Journal of General Virology, 83(10), pp. 2593-2600.
Smyth, E., Syme, C.D. , Blanch, E.W., Hecht, L., Vasak, M. and Barron, L.D. (2001) Solution structure of native proteins with irregular folds from Raman optical activity. Biopolymers, 58(2), pp. 138-151. (doi: 10.1002/1097-0282(200102)58:2<138::AID-BIP30>3.0.CO;2-W)
Research datasets
2021
Syme, C. , Bhella, D. and Hutchinson, E. (2021) A global map of the Zika virus phosphoproteome reveals host-driven regulation of viral budding. [Data Collection]
2020
Walton, F. , Bolling, J., Farrell, A., MacEwen, J., Syme, C. , Gonzalez Jimenez, M. , Senn, H. , Wilson, C. , Cinque, G. and Wynne, K. (2020) Polyamorphism mirrors polymorphism in the liquid–liquid transition of a molecular liquid. [Data Collection]
2017
Syme, C. , Mosses, J., Gonzalez-Jimenez, M., Shebanova, O., Walton, F. and Wynne, K. (2017) Frustration of crystallisation by a liquid-crystal phase. [Data Collection]