Professor Andrew Sutherland
- Professor of Organic Chemistry (School of Chemistry)
telephone:
01413305936
email:
Andrew.Sutherland@glasgow.ac.uk
C5-06, Chemistry, Joseph Black Building, Glasgow G12 8QQ
https://orcid.org/0000-0001-7907-5766Research interests
Research Interests
Research in the Sutherland group is focused on a number of key areas. Our main programme of research centres on molecular imaging of disease. We have a number of projects that develop novel PET and SPECT tracers for the radionuclide imaging of a range of neurological diseases as well as cancer. We are also investigating amino acid based fluorescent probes for cell imaging. Supporting these projects is a synthetic chemistry programme, which seeks to develop new transition metal catalysed transformations and one-pot multi-reaction processes for the rapid preparation of polycyclic drug-like scaffolds and natural products.
Research Topics
PET and SPECT Imaging Agents
Fluorescent Amino Acids
Transition metal catalysed reactions
One-pot multi-reaction processes
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Publication Highlights
- M. C. Henry and A. Sutherland, Synthesis of Benzo[b]furans by Intramolecular C-O Bond Formation using Iron and Copper Catalysis, Org. Lett., 2020, 22, 2766-2770.
- J. D. Bell, A. H. Harkiss, D. Nobis, E. Malcolm, A. Knuhtsen, C. R. Wellaway, A. G. Jamieson, S. W. Magennis and A. Sutherland, Conformationally Rigid Pyrazoloquinazoline alpha-Amino Acids: One- and Two-Photon Induced Fluorescence, Chem. Commun., 2020, 56, 1887-1890.
- J. J. Molloy, K. M. O’Rourke, C. P. Frias, N. L. Sloan, M. J. West, S. L. Pimlott, A. Sutherland and A. J. B. Watson, Mechanism of Cu-Catalyzed Aryl Boronic Acid Halodeboronation Using Electrophilic Halogen: Development of a Base-Catalyzed Iododeboronation for Radiolabeling Applications, Org. Lett., 2019, 21, 2488-2492.
- F. Zmuda, A. Blair, M. C. Liuzzi, G. Malviya, A. J. Chalmers, D. Lewis, A. Sutherland and S. L. Pimlott, An 18F-Labeled Poly(ADP-ribose) Polymerase Positron Emission Tomography Imaging Agent, J. Med. Chem., 2018, 61, 4103-4114.
- N. L. Sloan, S. K. Luthra, G. McRobbie, S. L. Pimlott and A. Sutherland, One-Pot Radioiodination of Aryl Amines via Stable Diazonium Salts: Preparation of 125I-Imaging Agents, Chem. Commun., 2017, 53, 11008-11011.
Research groups
Publications
2025
Waddell, L. J.N., Okunade, O. A.M., Dodds, A. C., Lok, M. C.H., Khanizeman, R. N. and Sutherland, A. (2025) Iron-catalyzed thioarylation of arenes using saccharin-derived reagents. Journal of Organic Chemistry, (Accepted for Publication)
Zeng, L., Marshall, O., McGrory, R., Clarke, R. , Brown, R. J., Kadodwala, M. , Thomson, A. R. and Sutherland, A. (2025) Synthesis of fluorescent dibenzofuran α-amino acids: conformationally rigid analogues of tyrosine. Organic Letters, (Accepted for Publication)
Marshall, O., McGrory, R., Songsri, S., Thomson, A. R. and Sutherland, A. (2025) Expedient discovery of fluorogenic amino acid-based probes via one-pot palladium-catalysed arylation of tyrosine. Chemical Science, (Accepted for Publication)
Morgan, T. E. F., Grant, E. K., Shaw, R. C., Waddell, L. J. N., Henry, M. C., McErlain, H., Alcaide-Corral, C. J., Pimlott, S. L. , Tavares, A. A. S. and Sutherland, A. (2025) Synthesis and evaluation of 6-arylaminobenzamides as positron emission tomography imaging ligands for the sphingosine-1-phosphate-5 receptor. RSC Medicinal Chemistry, (doi: 10.1039/D4MD00929K) (Early Online Publication)
2024
Chaubey, S. K. et al. (2024) Ultrasensitive Raman detection of biomolecular conformation at the attomole scale using chiral nanophotonics. Small, 20(45), 2404536. (doi: 10.1002/smll.202404536)
Burianova, V. K., Mcerlain, H. and Sutherland, A. (2024) Transition metal-mediated radiohalogenation using aryl boron reagents. Synthesis, (doi: 10.1055/s-0043-1775408) (Early Online Publication)
Songsri, S., McErlain, H. and Sutherland, A. (2024) Stereoselective synthesis of meso- and L,L-diaminopimelic acids from enone-derived α-amino acids. Journal of Organic Chemistry, 89(14), pp. 10363-10370. (doi: 10.1021/acs.joc.4c00916) (PMID:38955772) (PMCID:PMC11267594)
Riley, L. M. , Marshall, O., Harkiss, A. H., Senn, H. M. and Sutherland, A. (2024) Synthesis of β-pyridyl α-amino acids: conformationally sensitive charge transfer-based fluorophores. Organic Letters, 26(25), pp. 5391-5395. (doi: 10.1021/acs.orglett.4c01951) (PMID:38865167) (PMCID:PMC11217948)
Clarke, R. , Zeng, L., Atkinson, B. C., Kadodwala, M. , Thomson, A. R. and Sutherland, A. (2024) Fluorescent carbazole-derived α-amino acids; structural mimics of tryptophan. Chemical Science, 15(16), pp. 5944-5949. (doi: 10.1039/D4SC01173B) (PMID:38665535) (PMCID:PMC11040653)
Hill, R. A. and Sutherland, A. (2024) Hot off the press. Natural Product Reports, 41(4), pp. 520-524. (doi: 10.1039/d4np90015d) (PMID:38616726)
Knyzeliene, A., MacAskill, M. G., Alcaide-Corral, C. J., Morgan, T. E., Henry, M. C., Lucatelli, C., Pimlott, S. L. , Sutherland, A. and Tavares, A. A.S. (2024) [18F]LW223 has low non-displaceable binding in murine brain, enabling high sensitivity TSPO PET imaging. Journal of Cerebral Blood Flow and Metabolism, 44(3), pp. 397-406. (doi: 10.1177/0271678x231205661) (PMID:37795635) (PMCID:PMC10870961)
McErlain, H., Andrews, M. J., Watson, A. J.B., Pimlott, S. L. and Sutherland, A. (2024) Ligand-enabled copper-mediated radioiodination of arenes. Organic Letters, 26(7), pp. 1528-1532. (doi: 10.1021/acs.orglett.4c00356) (PMID:38335124) (PMCID:PMC10897930)
Hill, R. A. and Sutherland, A. (2024) Hot off the press. Natural Product Reports, 41(2), pp. 157-161. (doi: 10.1039/d4np90005g) (PMID:38318713)
Waddell, L. J.N., Wilson, C. and Sutherland, A. (2024) Trifluoromethylthiolation of Arenes using Lewis acid and Lewis base dual catalysis. Journal of Organic Chemistry, 89(2), pp. 1275-1284. (doi: 10.1021/acs.joc.3c02571) (PMID:38156642)
2023
Dodds, A. C., Sansom, H. G., Magennis, S. W. and Sutherland, A. (2023) Synthesis of Thiazoloindole α‑Amino Acids: Chromophores Amenable to One- and Two-Photon Induced Fluorescence. Organic Letters, 25(49), pp. 8942-8946. (doi: 10.1021/acs.orglett.3c03851) (PMID:38055619) (PMCID:PMC10729019)
Dodds, A. C., Waddell, L. J.N. and Sutherland, A. (2023) Regioselective functionalization of arenes using iron triflimide catalysis. Synlett, 34(16), pp. 1852-1865. (doi: 10.1055/s-0042-1751445)
McGrory, R., Clarke, R. , Marshall, O. and Sutherland, A. (2023) Fluorescent α-amino acids via Heck–Matsuda reactions of phenylalanine-derived arenediazonium salts. Organic and Biomolecular Chemistry, 21(34), pp. 6932-6939. (doi: 10.1039/d3ob01096a) (PMID:37580965)
Songsri, S., Harkiss, A. H. and Sutherland, A. (2023) Synthesis and photophysical properties of charge-transfer based pyrimidine-derived ∝-amino acids. Journal of Organic Chemistry, 88(18), pp. 13214-13224. (doi: 10.1021/acs.joc.3c01437) (PMID:37621156) (PMCID:PMC10507667)
McGrory, R., Morgan, D. C., Jamieson, A. G. and Sutherland, A. (2023) Rotamer-controlled dual emissive α-amino acids. Organic Letters, 25(31), pp. 5844-5849. (doi: 10.1021/acs.orglett.3c02112) (PMID:37506290) (PMCID:PMC10425982)
Waddell, L. J.N., Senkans, M. R. and Sutherland, A. (2023) Regioselective C–H thiocyanation of arenes by iron(III) chloride catalysis. Journal of Organic Chemistry, 88(11), pp. 7208-7218. (doi: 10.1021/acs.joc.3c00454) (PMID:37158540)
Hill, R. A. and Sutherland, A. (2023) Hot off the press. Natural Product Reports, 40(4), pp. 761-765. (doi: 10.1039/D3NP90016A) (PMID:37038828)
Riley, L., Mclay, T. N. and Sutherland, A. (2023) Synthesis and fluorescent properties of alkynyl- and alkenyl-fused benzotriazole-derived α-amino acids. Journal of Organic Chemistry, 88(4), pp. 2453-2463. (doi: 10.1021/acs.joc.2c02886) (PMID:36749161) (PMCID:PMC9942204)
Hill, R. A. and Sutherland, A. (2023) Hot off the press. Natural Product Reports, 40(2), pp. 223-227. (doi: 10.1039/D3NP90007J) (PMID:36756783)
2022
Hill, R. A. and Sutherland, A. (2022) Hot off the press. Natural Product Reports, 39(12), pp. 2209-2214. (doi: 10.1039/D2NP90043B) (PMID:36412123)
Tabouillot, V. et al. (2022) Near-field probing of optical superchirality with plasmonic circularly polarized luminescence for enhanced bio-detection. ACS Photonics, 9(11), pp. 3617-3624. (doi: 10.1021/acsphotonics.2c01073) (PMID:36411820)
McErlain, H., McLean, E. B., Morgan, T. E. F., Burianova, V. K., Tavares, A. A. S. and Sutherland, A. (2022) Organocatalytic asymmetric synthesis of SynVesT-1, A synaptic density positron emission tomography imaging agent. Journal of Organic Chemistry, 87(21), pp. 14443-14451. (doi: 10.1021/acs.joc.2c01895) (PMID:36222243)
Hill, R. A. and Sutherland, A. (2022) Hot off the press. Natural Product Reports, 39(10), pp. 1904-1909. (doi: 10.1039/D2NP90034C)
Waddell, L., Henry, M., Mostafa, M. and Sutherland, A. (2022) One-pot synthesis of diaryl sulfonamides using an iron and copper catalyzed aryl C–H amidation process. Synthesis, 54(20), pp. 4551-4560. (doi: 10.1055/a-1884-6988)
Hill, R. A. and Sutherland, A. (2022) Hot off the press. Natural Product Reports, 39(8), pp. 1539-1543. (doi: 10.1039/D2NP90026B) (PMID:35929527)
Dodds, A. C., Puddu, S. and Sutherland, A. (2022) Thioarylation of anilines using dual catalysis: two-step synthesis of phenothiazines. Organic and Biomolecular Chemistry, 20(28), pp. 5602-5614. (doi: 10.1039/D2OB01082H) (PMID:35796590)
Hill, R. A. and Sutherland, A. (2022) Hot off the press. Natural Product Reports, 39(6), pp. 1117-1121. (doi: 10.1039/D2NP90019J)
Hill, R. A. and Sutherland, A. (2022) Hot off the press. Natural Product Reports, 39(4), pp. 737-741. (doi: 10.1039/D2NP90011D) (PMID:35362487)
Dodds, A. C. and Sutherland, A. (2022) Synthesis of phenoxathiins using an iron-catalysed C–H thioarylation. Organic and Biomolecular Chemistry, 20(8), pp. 1738-1748. (doi: 10.1039/D2OB00022A) (PMID:35142330)
Hill, R. A. and Sutherland, A. (2022) Hot off the press. Natural Product Reports, 39(2), pp. 217-221. (doi: 10.1039/D2NP90004A)
2021
Mcerlain, H., Riley, L. M. and Sutherland, A. (2021) Palladium-catalyzed C—P bond-forming reactions of aryl nonaflates accelerated by iodide. Journal of Organic Chemistry, 86(23), pp. 17036-17049. (doi: 10.1021/acs.joc.1c02172) (PMID:34726917)
Hill, R. A. and Sutherland, A. (2021) Hot off the press. Natural Product Reports, 38(12), pp. 2139-2144. (doi: 10.1039/D1NP90046C) (PMID:34851342)
MacAskill, M. G., Wimberley, C., Morgan, T. E. F., Alcaide‑Corral, C. J., Newby, D. E., Lucatelli, C., Sutherland, A. , Pimlott, S. L. and Tavares, A. A. S. (2021) Modelling [18F]LW223 PET data using simplified imaging protocols for quantification of TSPO expression in the rat heart and brain. European Journal of Nuclear Medicine and Molecular Imaging, 49, pp. 137-145. (doi: 10.1007/S00259-021-05482-1) (PMID:34338808) (PMCID:PMC8712302)
Morgan, T. E.F., Riley, L. M., Tavares, A. A.S. and Sutherland, A. (2021) Automated Radiosynthesis of cis- and trans-4-[18F]Fluoro-L-proline using [18F]Fluoride. Journal of Organic Chemistry, 86(20), pp. 14054-14060. (doi: 10.1021/acs.joc.1c00755) (PMID:33913318) (PMCID:PMC8524414)
Hill, R. A. and Sutherland, A. (2021) Hot off the press. Natural Product Reports, 38(10), pp. 1715-1719. (doi: 10.1039/D1NP90037D)
Hill, R. A. and Sutherland, A. (2021) Hot off the press. Natural Product Reports, 38(8), pp. 1418-1422. (doi: 10.1039/D1NP90030G)
Hill, R. A. and Sutherland, A. (2021) Hot off the press. Natural Product Reports, 38(6), pp. 1053-1057. (doi: 10.1039/D1NP90020J)
Dodds, A. C. and Sutherland, A. (2021) Regioselective C-H thioarylation of electron-rich arenes by iron(III) triflimide catalysis. Journal of Organic Chemistry, 86(8), pp. 5922-5932. (doi: 10.1021/acs.joc.1c00448) (PMID:33783222)
Hill, R. A. and Sutherland, A. (2021) Hot off the press. Natural Product Reports, 38(4), pp. 677-681. (doi: 10.1039/D1NP90013G)
MacAskill, M. G. et al. (2021) Quantification of macrophage-driven inflammation during myocardial infarction with 18F-LW223, a novel TSPO radiotracer with binding independent of the rs6971 human polymorphism. Journal of Nuclear Medicine, 62(4), pp. 536-544. (doi: 10.2967/jnumed.120.243600) (PMID:32859708) (PMCID:PMC8049364)
Welch, A., Tavares, A. A. S., Pimlott, S. and Sutherland, A. (2021) PET and SPECT in drug development. In: Abraham, Donald J. (ed.) Burger's Medicinal Chemistry, Drug Discovery and Development. Wiley. ISBN 9780470278154 (doi: 10.1002/0471266949.bmc254.pub2)
Hill, R. A. and Sutherland, A. (2021) Hot off the press. Natural Product Reports, 38(2), pp. 287-291. (doi: 10.1039/D1NP90005F)
McGrory, R., Faggyas, R. and Sutherland, A. (2021) One-pot synthesis of N-substituted benzannulated triazoles via stable arene diazonium salts. Organic and Biomolecular Chemistry, 19(27), pp. 6127-6140. (doi: 10.1039/D1OB00968K) (PMID:34179913)
2020
Hill, R. A. and Sutherland, A. (2020) Hot off the press. Natural Product Reports, 37(12), pp. 1556-1560. (doi: 10.1039/D0NP90047H)
Hill, R. A. and Sutherland, A. (2020) Hot off the press. Natural Product Reports, 37(10), pp. 1294-1299. (doi: 10.1039/D0NP90037K)
Hill, R. A. and Sutherland, A. (2020) Hot off the press. Natural Product Reports, 37(8), pp. 1038-1042. (doi: 10.1039/D0NP90029J)
Dubost, E., Mcerlain, H., Babin, V., Sutherland, A. and Cailly, T. (2020) Recent advances in synthetic methods for radioiodination. Journal of Organic Chemistry, 85(13), pp. 8300-8310. (doi: 10.1021/acs.joc.0c00644) (PMID:32369696)
Hill, R. A. and Sutherland, A. (2020) Hot off the press. Natural Product Reports, 37(6), pp. 747-751. (doi: 10.1039/D0NP90022B)
Sood, D. E., Champion, S., Dawson, D. M., Chabbra, S., Bode, B. E., Sutherland, A. and Watson, A. J. B. (2020) Deoxyfluorination with CuF2: enabled by using a Lewis base activating group. Angewandte Chemie (International Edition), 59(22), pp. 8460-8463. (doi: 10.1002/anie.202001015) (PMID:32109331)
Henry, M. C., Abbinante, V. M. and Sutherland, A. (2020) Iron-catalyzed regioselective synthesis of 2-arylbenzoxazoles and 2-arylbenzothiazoles via alternative reaction pathways. European Journal of Organic Chemistry, 2020(19), pp. 2819-2826. (doi: 10.1002/ejoc.202000014)
Henry, M. C. and Sutherland, A. (2020) Synthesis of benzo[b]furans by intramolecular C–O bond formation using iron and copper catalysis. Organic Letters, 22(7), pp. 2766-2770. (doi: 10.1021/acs.orglett.0c00754) (PMID:32186389) (PMCID:PMC7146889)
Hill, R. A. and Sutherland, A. (2020) Hot off the press. Natural Product Reports, 37(4), pp. 472-476. (doi: 10.1039/D0NP90014A)
Hill, R. A. and Sutherland, A. (2020) Hot off the press. Natural Product Reports, 37(2), pp. 145-149. (doi: 10.1039/D0NP90004D)
Bell, J. D., Harkiss, A. H., Nobis, D., Malcolm, E., Knuhtsen, A., Wellaway, C. R., Jamieson, A. G. , Magennis, S. W. and Sutherland, A. (2020) Conformationally rigid pyrazoloquinazoline α-amino acids: one- and two-photon induced fluorescence. Chemical Communications, 56(12), pp. 1887-1890. (doi: 10.1039/C9CC09064A) (PMID:31956866)
2019
Hill, R. A. and Sutherland, A. (2019) Hot off the press. Natural Product Reports, 36(12), pp. 1614-1618. (doi: 10.1039/C9NP90045D) (PMID:31777890)
Hill, R. A. and Sutherland, A. (2019) Hot off the press. Natural Product Reports, 36(10), pp. 1378-1382. (doi: 10.1039/C9NP90041A) (PMID:31538642)
Faggyas, R. J., Sloan, N. L., Buijs, N. and Sutherland, A. (2019) Synthesis of structurally diverse benzotriazoles via rapid diazotization and intramolecular cyclization of 1,2-aryldiamines. European Journal of Organic Chemistry, 2019(31-32), pp. 5344-5353. (doi: 10.1002/ejoc.201900463)
Hill, R. A. and Sutherland, A. (2019) Hot off the press. Natural Product Reports, 36(8), pp. 1039-1043. (doi: 10.1039/C9NP90031D) (PMID:31332420)
Bell, J. D., Morgan, T. E.F., Buijs, N., Harkiss, A. H., Wellaway, C. R. and Sutherland, A. (2019) Synthesis and photophysical properties of benzotriazole-derived unnatural α -amino acids. Journal of Organic Chemistry, 84(16), pp. 10436-10448. (doi: 10.1021/acs.joc.9b01685) (PMID:31340638)
MacAskill, M. G. et al. (2019) Kinetic modelling and quantification bias in small animal PET studies with [18F]AB5186, a novel 18 kDa translocator protein radiotracer. PLoS ONE, 14(5), e0217515. (doi: 10.1371/journal.pone.0217515) (PMID:31150436) (PMCID:PMC6544349)
Henry, M. C., McGrory, R., Faggyas, R. J., Mostafa, M. A.B. and Sutherland, A. (2019) One-pot ortho-amination of aryl C-H bonds using consecutive iron and copper catalysis: late-stage structural diversification of 3,4-dihydroquinolin-2-one. Organic and Biomolecular Chemistry, 17(18), pp. 4629-4639. (doi: 10.1039/C9OB00712A) (PMID:31020305)
Hill, R. A. and Sutherland, A. (2019) Hot off the press. Natural Product Reports, 36(6), pp. 850-854. (doi: 10.1039/C9NP90019E)
Molloy, J. J., O'Rourke, K., Frias, C. P., Sloan, N., West, M. J., Pimlott, S. L. , Sutherland, A. and Watson, A. J.B. (2019) Mechanism of Cu-catalyzed aryl boronic acid halodeboronation using electrophilic halogen: development of a base-catalyzed iododeboronation for radiolabeling applications. Organic Letters, 21(7), pp. 2488-2492. (doi: 10.1021/acs.orglett.9b00942) (PMID:30908055)
Hill, R. A. and Sutherland, A. (2019) Hot off the press. Natural Product Reports, 36(4), pp. 556-560. (doi: 10.1039/C9NP90010A)
Harkiss, A. H., Bell, J. D., Knuhtsen, A., Jamieson, A. G. and Sutherland, A. (2019) Synthesis and fluorescent properties of β-pyridyl α-amino acids. Journal of Organic Chemistry, 84(5), pp. 2879-2890. (doi: 10.1021/acs.joc.9b00036) (PMID:30726078)
Hill, R. A. and Sutherland, A. (2019) Hot off the press. Natural Product Reports, 36(2), pp. 258-262. (doi: 10.1039/C9NP90001B) (PMID:30667456)
Henry, M. C., Senn, H. M. and Sutherland, A. (2019) Synthesis of functionalized indolines and dihydrobenzofurans by iron and copper catalyzed aryl C-N and C-O bond formation. Journal of Organic Chemistry, 84(1), pp. 346-364. (doi: 10.1021/acs.joc.8b02888) (PMID:30520304)
Sutherland, A. (2019) Radiohalogenation of organic compounds: practical considerations and challenges for molecular imaging. Synthesis, 51(23), pp. 4368-4373. (doi: 10.1055/s-0037-1611885)
2018
Hill, R. A. and Sutherland, A. (2018) Hot off the press. Natural Product Reports, 35(12), pp. 1236-1240. (doi: 10.1039/C8NP90046A) (PMID:30474086)
Faggyas, R. J., Grace, M., Williams, L. and Sutherland, A. (2018) Multibond forming tandem reactions of anilines via stable aryl diazonium salts: one-pot synthesis of 3,4-dihydroquinolin-2-ones. Journal of Organic Chemistry, 83(20), pp. 12595-12608. (doi: 10.1021/acs.joc.8b01910) (PMID:30230840)
Hill, R. A. and Sutherland, A. (2018) Hot off the press. Natural Product Reports, 35(10), pp. 1024-1028. (doi: 10.1039/C8NP90032A) (PMID:30209473)
Bell, J. D., Harkiss, A. H., Wellaway, C. R. and Sutherland, A. (2018) Stereoselective synthesis of 2,6-trans-4-oxopiperidines using an acid-mediated 6-endo-trig cyclisation. Organic and Biomolecular Chemistry, 16(35), pp. 6410-6422. (doi: 10.1039/C8OB01363B) (PMID:30011344)
Hill, R. A. and Sutherland, A. (2018) Hot off the press. Natural Product Reports, 35(8), pp. 702-706. (doi: 10.1039/C8NP90024H) (PMID:30058659)
O'Rourke, K., Johnstone, E. S., Becker, H. M., Pimlott, S. L. and Sutherland, A. (2018) Exploring the functionalisation of the thieno[2,3-d]pyrimidinedione core: late stage access to highly substituted 5-carboxamide-6-aryl scaffolds. Tetrahedron, 74(30), pp. 4086-4094. (doi: 10.1016/j.tet.2018.06.019)
Hill, R. A. and Sutherland, A. (2018) Hot off the press. Natural Product Reports, 35(6), pp. 496-500. (doi: 10.1039/c8np90015a) (PMID:29878011)
Gibson, E. K. , Callison, J., Winfield, J. M., Sutherland, A. , Carr, R. H., Eaglesham, A., Parker, S. F. and Lennon, D. (2018) Spectroscopic characterization of model compounds, reactants, and byproducts connected with an isocyanate production chain. Industrial and Engineering Chemistry Research, 57(22), pp. 7355-7362. (doi: 10.1021/acs.iecr.8b00853)
Zmuda, F., Blair, A., Liuzzi, M. C., Malviya, G. , Chalmers, A. J. , Lewis, D., Sutherland, A. and Pimlott, S. L. (2018) An 18F-labeled poly(ADP-ribose) polymerase positron emission tomography imaging agent. Journal of Medicinal Chemistry, 61(9), pp. 4103-4114. (doi: 10.1021/acs.jmedchem.8b00138) (PMID:29630818) (PMCID:PMC6007963)
Hill, R. A. and Sutherland, A. (2018) Hot off the press. Natural Product Reports, 35, pp. 298-302. (doi: 10.1039/c8np90008f) (PMID:29532849)
Hill, R. A. and Sutherland, A. (2018) Hot off the press. Natural Product Reports, 35(2), pp. 132-136. (doi: 10.1039/c7np90051a) (PMID:29350723)
Webster, S., O'Rourke, K. M., Fletcher, C., Pimlott, S. L. , Sutherland, A. and Lee, A.-L. (2018) Rapid iododeboronation with and without gold catalysis: application to radiolabelling of arenes. Chemistry: A European Journal, 24(4), pp. 937-943. (doi: 10.1002/chem.201704534) (PMID:29105856) (PMCID:PMC5814724)
Harkiss, A. H. and Sutherland, A. (2018) Access to 2,6-disubstituted 4-oxopiperidines using a 6-endo-trig cyclization: stereoselective synthesis of spruce alkaloid and (+)-241D. Journal of Organic Chemistry, 83(1), pp. 535-542. (doi: 10.1021/acs.joc.7b02799) (PMID:29218988)
2017
Hill, R. A. and Sutherland, A. (2017) Hot off the press. Natural Product Reports, 34(12), pp. 1340-1344. (doi: 10.1039/c7np90044a) (PMID:29090285)
Faggyas, R. J., Calder, E. D.D., Wilson, C. and Sutherland, A. (2017) One-pot asymmetric synthesis of alkylidene 1-alkylindan-1-ols using Brønsted acid and palladium catalysis. Journal of Organic Chemistry, 82(21), pp. 11585-11593. (doi: 10.1021/acs.joc.7b02287) (PMID:28985675)
Sloan, N. L., Luthra, S. K., McRobbie, G., Pimlott, S. L. and Sutherland, A. (2017) One-pot radioiodination of aryl amines via stable diazonium salts: preparation of 125I-imaging agents. Chemical Communications, 53(80), pp. 11008-11011. (doi: 10.1039/C7CC06211G) (PMID:28849815)
Hill, R. A. and Sutherland, A. (2017) Hot off the press. Natural Product Reports, 34(10), pp. 1180-1184. (doi: 10.1039/c7np90040f) (PMID:28952651)
Henry, M. C., Sutherland, A. and Mostafa, M. A.B. (2017) Recent advances in transition-metal-catalyzed, directed Aryl C-H/N-H cross coupling reactions. Synthesis, 49(20), pp. 4586-4598. (doi: 10.1055/s-0036-1588536)
Hill, R. A. and Sutherland, A. (2017) Hot off the press. Natural Product Reports, 34(8), pp. 940-944. (doi: 10.1039/c7np90028g) (PMID:28717803)
Mostafa, M. A.B., Bowley, R. M., Racys, D. T., Henry, M. C. and Sutherland, A. (2017) Iron(III)-catalyzed chlorination of activated arenes. Journal of Organic Chemistry, 82(14), pp. 7529-7537. (doi: 10.1021/acs.joc.7b01225) (PMID:28661157)
Hill, R. A. and Sutherland, A. (2017) Hot off the press. Natural Product Reports, 34(6), pp. 566-570. (doi: 10.1039/c7np90017a) (PMID:28497154)
MacAskill, M., Zmuda, F., Lucatelli, C., Dweck, M., Gray, G., Newby, D., Sutherland, A. , Pimlott, S. and Tavares, A. (2017) Binding affinity profiles of isoquinoline carboxamide and phenoxyphenyl acetamide-based TSPO PET ligands in human brain and heart. Journal of Nuclear Medicine, 58(suppl1), p. 478.
Mostafa, M., McMillan, A. E. and Sutherland, A. (2017) Structural diversification of the aminobicyclo[4.3.0]nonane skeleton using alkynylsilyl-derived allylic trichloroacetimidates. Organic and Biomolecular Chemistry, 15(14), pp. 3035-3045. (doi: 10.1039/C7OB00456G) (PMID:28304410)
Hill, R. A. and Sutherland, A. (2017) Hot off the press. Natural Product Reports, 34(4), pp. 338-342. (doi: 10.1039/c7np90009k) (PMID:28322409)
Hill, R. A. and Sutherland, A. (2017) Hot off the press. Natural Product Reports, 34(2), pp. 130-134. (doi: 10.1039/c6np90051h) (PMID:28079908)
Sloan, N. L., Luthra, S. K., McRobbie, G., Pimlott, S. L. and Sutherland, A. (2017) Late stage iodination of biologically active agents using a one-pot process from aryl amines. RSC Advances, 7(86), pp. 54881-54891. (doi: 10.1039/C7RA11860K)
2016
Mostafa, M. A.B., Calder, E. D.D., Sutherland, A. and Racys, D. T. (2016) Intermolecular Aryl C-H amination using sequential iron and copper catalysis. Chemistry: A European Journal, 23(5), pp. 1044-1047. (doi: 10.1002/chem.201605671) (PMID:27918637)
Hill, R. A. and Sutherland, A. (2016) Hot off the press. Natural Product Reports, 33(12), pp. 1352-1356. (doi: 10.1039/c6np90047j) (PMID:27785514)
Sharif, S. A.I., Calder, E. D.D., Harkiss, A., Maduro, M. and Sutherland, A. (2016) Synthesis of allylic amide functionalized 2H-chromenes and coumarins using a one-pot overman rearrangement and gold(I)-catalyzed hydroarylation. Journal of Organic Chemistry, 81(20), pp. 9810-9819. (doi: 10.1021/acs.joc.6b01881) (PMID:27680202)
Harkiss, A. and Sutherland, A. (2016) Recent advances in the synthesis and application of fluorescent α-amino acids. Organic and Biomolecular Chemistry, 14(38), pp. 8911-8921. (doi: 10.1039/C6OB01715K) (PMID:27714204)
Hill, R. A. and Sutherland, A. (2016) Correction: Hot off the press. Natural Product Reports, 33(10), p. 1239. (doi: 10.1039/c6np90040b) (PMID:27714075)
Hill, R. A. and Sutherland, A. (2016) Hot off the press. Natural Product Reports, 33(10), pp. 1126-1130. (doi: 10.1039/c6np90039a) (PMID:27785514)
Sharif, S. A.I., Calder, E. D.D., Delolo, F. G. and Sutherland, A. (2016) Synthesis of 5-Amino-2,5-dihydro-1H-benzo[b]azepines using a one-pot multibond forming process. Journal of Organic Chemistry, 81(15), pp. 6697-6706. (doi: 10.1021/acs.joc.6b01357) (PMID:27414232)
Hill, R. A. and Sutherland, A. (2016) Hot off the press. Natural Product Reports, 33(8), pp. 915-919. (doi: 10.1039/c6np90030e)
Hill, R. A. and Sutherland, A. (2016) Hot off the press. Natural Product Reports, 33(6), pp. 742-746. (doi: 10.1039/C6NP90022D) (PMID:27173803)
Hill, R. A. and Sutherland, A. (2016) Hot off the press. Natural Product Reports, 33(4), pp. 530-534. (doi: 10.1039/c6np90012g)
Mostafa, M. A.B., Grafton, M. W., Wilson, C. and Sutherland, A. (2016) A one-pot, three-step process for the diastereoselective synthesis of aminobicyclo[4.3.0]nonanes using consecutive palladium(II)- and ruthenium(II)-catalysis. Organic and Biomolecular Chemistry, 14(14), pp. 3284-3297. (doi: 10.1039/C6OB00165C) (PMID:26932788)
Cant, A. A., Racys, D. T., Pimlott, S. L. and Sutherland, A. (2016) New reactions for the synthesis of aryl iodides and the generation of single-photon emission computed tomography imaging agents. 24th international isotope society (UK group) symposium, Cambridge, UK, 06 Nov 2015. p. 182. (doi: 10.1002/jlcr.3377)
Racys, D. T., Sharif, S. A.I., Pimlott, S. L. and Sutherland, A. (2016) Silver(I)-catalyzed iodination of Arenes: Tuning the Lewis acidity of N-iodosuccinimide activation. Journal of Organic Chemistry, 81(3), pp. 772-780. (doi: 10.1021/acs.joc.5b02761) (PMID:26795534)
Hill, R. A. and Sutherland, A. (2016) Hot off the press. Natural Product Reports, 33(2), pp. 122-126. (doi: 10.1039/c5np90052b)
2015
Hill, R. A. and Sutherland, A. (2015) Hot off the press. Natural Product Reports, 32(12), pp. 1612-1616. (doi: 10.1039/c5np90047f)
Zmuda, F., Malviya, G. , Blair, A., Boyd, M., Chalmers, A. J. , Sutherland, A. and Pimlott, S. L. (2015) Synthesis and evaluation of a radioiodinated tracer with specificity for poly(ADP-ribose) polymerase-1 (PARP-1) in vivo. Journal of Medicinal Chemistry, 58(21), pp. 8683-8693. (doi: 10.1021/acs.jmedchem.5b01324) (PMID:26469301)
Racys, D. T., Warrilow, C. E., Pimlott, S. L. and Sutherland, A. (2015) Highly regioselective iodination of arenes via iron(III)-catalyzed activation of N-iodosuccinimide. Organic Letters, 17(19), pp. 4782-4785. (doi: 10.1021/acs.orglett.5b02345) (PMID:26394175)
Hill, R. A. and Sutherland, A. (2015) Hot off the press. Natural Product Reports, 32(10), pp. 1364-1368. (doi: 10.1039/c5np90039e)
Hill, R. A. and Sutherland, A. (2015) Hot off the press. Natural Product Reports, 32(8), pp. 1165-1169. (doi: 10.1039/c5np90032h)
Hill, R. A. and Sutherland, A. (2015) Hot off the press. Natural Product Reports, 32(6), pp. 760-764. (doi: 10.1039/c5np90021b)
Calder, E. D.D. and Sutherland, A. (2015) Enantioselective synthesis of 3-methyleneindan-1-ols via a one-pot allylboration–Heck reaction of 2-bromobenzaldehydes. Organic Letters, 17(10), pp. 2514-2517. (doi: 10.1021/acs.orglett.5b01047) (PMID:25933177)
Calder, E. D.D., Sharif, S. A.I., McGonagle, F. I. and Sutherland, A. (2015) One-pot synthesis of 5-amino-2,5-dihydro-1-benzoxepines: access to pharmacologically active heterocyclic scaffolds. Journal of Organic Chemistry, 80(9), pp. 4683-4696. (doi: 10.1021/acs.joc.5b00583) (PMID:25847814)
Gilfillan, L., Artschwager, R., Harkiss, A. H., Liskamp, R. M.J. and Sutherland, A. (2015) Synthesis of pyrazole containing α-amino acids via a highly regioselective condensation/aza-Michael reaction of β-aryl α,β-unsaturated ketones. Organic and Biomolecular Chemistry, 13(15), pp. 4514-4523. (doi: 10.1039/C5OB00364D) (PMID:25774874)
Hill, R. A. and Sutherland, A. (2015) Hot off the press. Natural Product Reports, 32(4), pp. 512-516. (doi: 10.1039/c5np90013a)
Hill, R. A. and Sutherland, A. (2015) Hot off the press. Natural Product Reports, 32(2), pp. 111-115. (doi: 10.1039/c4np90046d)
Reid, C. M., Fanning, K. N., Fowler, L. S. and Sutherland, A. (2015) Synthesis and reactivity of 4-oxo-5-trimethylsilanyl derived α-amino acids. Tetrahedron, 71(2), pp. 245-251. (doi: 10.1016/j.tet.2014.11.059)
Blair, A., Zmuda, F., Malviya, G. , Chalmers, A. J. , Dewar, D. , Pimlott, S. L. and Sutherland, A. (2015) A novel 18F-labelled high affinity agent for PET imaging of the translocator protein. Chemical Science, 6(8), pp. 4772-4777. (doi: 10.1039/C5SC01647A)
2014
Hill, R. A. and Sutherland, A. (2014) Hot off the press. Natural Product Reports, 31(12), pp. 1671-1675. (doi: 10.1039/C4NP90041C)
Grafton, M., Johnson, S. A., Farrugia, L. J. and Sutherland, A. (2014) Diastereoselective synthesis of highly substituted polycyclic scaffolds via a one-pot four-step tandem catalytic process. Tetrahedron Letters, 70(40), pp. 7133-7141. (doi: 10.1016/j.tet.2014.06.020)
Hill, R. A. and Sutherland, A. (2014) Hot off the press. Natural Product Reports, 31(10), pp. 1242-1246. (doi: 10.1039/C4NP90032D)
Hill, R. A. and Sutherland, A. (2014) Hot off the press. Natural Product Reports, 31(9), pp. 1083-1087. (doi: 10.1039/C4NP90023E)
Calder, E. D.D., McGonagle, F. I., Harkiss, A. H., McGonagle, G. A. and Sutherland, A. (2014) Preparation of amino-substituted indenes and 1,4-dihydronaphthalenes using a one-pot multireaction approach: total synthesis of oxybenzo[c]phenanthridine alkaloids. Journal of Organic Chemistry, 79(16), pp. 7633-7648. (doi: 10.1021/jo5014492) (PMID:25060853)
Hill, R. A. and Sutherland, A. (2014) Hot off the press. Natural Product Reports, 31(6), pp. 706-710. (doi: 10.1039/C4NP90015D)
Calder, E. D.D., Grafton, M. W. and Sutherland, A. (2014) One-pot multi-reaction processes: synthesis of natural products and drug-like scaffolds. Synlett, 25(8), pp. 1068-1080. (doi: 10.1055/s-0033-1340683)
Hill, R. A. and Sutherland, A. (2014) Hot off the press. Natural Product Reports, 31(4), pp. 414-418. (doi: 10.1039/C4NP90007C)
Hill, R. A. and Sutherland, A. (2014) Hot off the press. Natural Product Reports, 31(4), pp. 414-418. (doi: 10.1039/C3NP90044D)
Zaed, A. M., Grafton, M. W., Ahmad, S. and Sutherland, A. (2014) Asymmetric synthesis of cis-aminocyclopentenols, building blocks for medicinal chemistry. Journal of Organic Chemistry, 79(3), pp. 1511-1515. (doi: 10.1021/jo402712r)
2013
Hill, R. A. and Sutherland, A. (2013) Hot off the press. Natural Product Reports, 30(12), pp. 1462-1466. (doi: 10.1039/C3NP90036C)
Hill, R. A. and Sutherland, A. (2013) Hot off the press. Natural Product Reports, 30(12), pp. 1462-1466. (doi: 10.1039/C3NP90029K)
Hill, R. A. and Sutherland, A. (2013) Hot off the press. Natural Product Reports, 30(12), pp. 1074-1078. (doi: 10.1039/C3NP90022C)
Cant, A.A., Champion, S. , Bhalla, R., Pimlott, S.L. and Sutherland, A. (2013) Nickel-mediated radioiodination of aryl and heteroaryl bromides: rapid synthesis of tracers for SPECT imaging. Angewandte Chemie (International Edition), 52(30), pp. 7829-7832. (doi: 10.1002/anie.201302800)
Calder, E.D.D., Zaed, A.M. and Sutherland, A. (2013) Preparation of anti-vicinal amino alcohols: asymmetric synthesis of D-erythro-Sphinganine, (+)-spisulosine and D-ribo-phytosphingosine. Journal of Organic Chemistry, 78(14), pp. 7223-7233. (doi: 10.1021/jo401211j)
Grafton, M. W., Farrugia, L. J. and Sutherland, A. (2013) Synthesis of amino substituted indanes and tetralins via consecutive multi-bond forming tandem processes. Journal of Organic Chemistry, 78(14), pp. 7199-7207. (doi: 10.1021/jo401182r)
Gilfillan, L., Blair, A., Morris, B. , Pratt, J., Schweiger, L., Pimlott, S. and Sutherland, A. (2013) Synthesis and biological evaluation of novel 2,3-dihydro-1H-1,5-benzodiazepin-2-ones; potential imaging agents of the metabotropic glutamate 2 receptor. MedChemComm, 4(7), pp. 1118-1123. (doi: 10.1039/c3md00110e)
Hill, R. A. and Sutherland, A. (2013) Hot off the press. Natural Product Reports, 30(12), pp. 760-764. (doi: 10.1039/C3NP90015K)
Hill, R. A. and Sutherland, A. (2013) Hot off the press. Natural Product Reports, 30(12), pp. 485-489. (doi: 10.1039/C3NP90007J)
Blair, A., Stevenson, L., Dewar, D. , Pimlott, S.L. and Sutherland, A. (2013) Structure–activity relationships of novel iodinated quinoline-2-carboxamides for targeting the translocator protein. MedChemComm, 4(11), pp. 1461-1466. (doi: 10.1039/c3md00249g)
Blair, A., Pimlott, S. , Schwieger, L. and Sutherland, A. (2013) New PET and SPECT imaging agents for the translocator protein (18 kDa). 245th National Spring Meeting of the American-Chemical-Society (ACS), New Orleans, Louisiana, USA, 07-11 Apr 2013.
Hill, R.A. and Sutherland, A. (2013) Hot off the press. Natural Product Reports, 30(2), pp. 213-217. (doi: 10.1039/C2NP90051C)
2012
Blair, A., Stevenson, L. and Sutherland, A. (2012) Synthesis of the isoquinoline alkaloid, crispine C. Tetrahedron Letters, 53(32), pp. 4084-4086. (doi: 10.1016/j.tetlet.2012.05.113)
Tavares, A. A. S., Jobson, N. K., Dewar, D. , Sutherland, A. , Pimlott, S. L. , Batis, J., Barret, O., Baldwin, R., Seibyl, J. and Tamagnan, G. (2012) Radioiodinated reboxetine analogues for imaging of the norepinephrine transporters in brain using single photon emission computed tomography. 9th International Symposium on Functional Neuroreceptor Mapping of the Living Brain (NRM), Baltimore, Maryland, USA, 09-11 Aug 2012. S103-S104. (doi: 10.1038/jcbfm.2012.79)
Ahmad, S., Swift, M., Farrugia, L., Senn, H.M. and Sutherland, A. (2012) Stereoselective synthesis of functionalised carbocyclic amides: construction of the syn-(4aS,10bS)-phenanthridone skeleton. Organic and Biomolecular Chemistry, 10(19), pp. 3937-3945. (doi: 10.1039/C2OB25334H)
Hill, R. and Sutherland, A. (2012) Hot off the press. Natural Product Reports, 29(2), p. 129. (doi: 10.1039/C1NP90052H)
Ahmad, S. and Sutherland, A. (2012) Stereoselective synthesis of hydroxylated 3-aminoazepanes using a multi-bond forming, three-step tandem process. Organic and Biomolecular Chemistry, 10(41), pp. 8251-8259. (doi: 10.1039/C2OB26544C)
Cant, A., Bhalla, R., Pimlott, S.L. and Sutherland, A. (2012) Nickel-catalysed aromatic Finkelstein reaction of aryl and heteroaryl bromides. Chemical Communications, 48(33), pp. 3993-3995. (doi: 10.1039/c2cc30956d)
Daly, M., Cant, A.A., Fowler, L.S., Simpson, G.L., Senn, H.M. and Sutherland, A. (2012) Switching the stereochemical outcome of 6-endo-trig cyclizations; Synthesis of 2,6-Cis-6-substituted 4-oxopipecolic acids. Journal of Organic Chemistry, 77(22), pp. 10001-10009. (doi: 10.1021/jo3022583)
Grafton, M.W., Farrugia, L.J., Senn, H.M. and Sutherland, A. (2012) Discovery of a multi-bond forming, four-step tandem process: construction of drug-like polycyclic scaffolds. Chemical Communications, 48, pp. 7994-7996. (doi: 10.1039/c2cc33649a)
Hill, R.A. and Sutherland, A. (2012) Hot off the press. Natural Product Reports, 29(4), pp. 435-439. (doi: 10.1039/C2NP90008D)
Hill, R.A. and Sutherland, A. (2012) Hot off the press. Natural Product Reports, 29(6), pp. 617-621. (doi: 10.1039/C2NP90016E)
Hill, R.A. and Sutherland, A. (2012) Hot off the press. Natural Product Reports, 29(8), p. 829. (doi: 10.1039/C2NP90024F)
Hill, R.A. and Sutherland, A. (2012) Hot off the press. Natural Product Reports, 29(10), pp. 1033-1037. (doi: 10.1039/C2NP90033E)
Hill, R.A. and Sutherland, A. (2012) Hot off the press. Natural Product Reports, 29(12), pp. 1377-1381. (doi: 10.1039/C2NP90041F)
Sutherland, A. and Cant, A. (2012) Asymmetric synthesis of pipecolic acid and derivatives. Synthesis, 44(13), pp. 1935-1950. (doi: 10.1055/s-0031-1289767)
Tavares, A.A.S., Jobson, N.K., Dewar, D. , Sutherland, A. , Pimlott, S.L. , Batis, J., Barret, O., Seibyl, J. and Tamagnan, G. (2012) Iodine-123 labeled reboxetine analogues for imaging of noradrenaline transporter in brain using single photon emission computed tomography. Synapse, 66(11), pp. 923-930. (doi: 10.1002/syn.21585)
2011
Hill, R. and Sutherland, A. (2011) Hot off the press. Natural Product Reports, 28(12), p. 1879. (doi: 10.1039/C1NP90043A)
Zaed, A. and Sutherland, A. (2011) Total synthesis of clavaminol A, C and H. Organic and Biomolecular Chemistry, 9(23), pp. 8030-8037. (doi: 10.1039/C1OB06060K)
Daly, M., Gill, K., Sime, M., Simpson, G.L. and Sutherland, A. (2011) A new general approach for the stereocontrolled synthesis of functionalised γ- and δ-lactams. Organic and Biomolecular Chemistry, 9(19), p. 6761. (doi: 10.1039/C1OB05833A)
Fowler, L.S., Thomas, L.H., Ellis, D. and Sutherland, A. (2011) A one-pot reductive amination/6-endo-trig cyclisation for the stereoselective synthesis of 6-substituted-4-oxopipecolic acids. Chemical Communications, 47(23), pp. 6569-6571. (doi: 10.1039/c1cc11916h)
Tavares, A.A.S., Jobson, N.K., Dewar, D. , Sutherland, A. and Pimlott, S.L. (2011) Development of the radiosynthesis of high-specific-activity 123I-NKJ64. Nuclear Medicine and Biology, 38(4), pp. 493-500. (doi: 10.1016/j.nucmedbio.2010.11.011)
Fowler, L.S., Sutherland, A. , Procter, J. and Molander, G.A. (2011) Product class 6: acyclic and semicyclic o/o acetals. In: Ishihara, K., Krause, N. and Procter, D. (eds.) Science of Synthesis Knowledge Updates. Thieme, p. 121. ISBN 9783131541611
Ahmad, S., Thomas, L.H. and Sutherland, A. (2011) Stereoselective synthesis of polyhydroxylated aminocyclohexanes. Organic and Biomolecular Chemistry, 9, pp. 2801-2808. (doi: 10.1039/C0OB00619J)
Hill, R.A. and Sutherland, A. (2011) Hot off the press. Natural Product Reports, 28(6), pp. 1031-1034. (doi: 10.1039/C1NP90013G)
Hill, R.A. and Sutherland, A. (2011) Hot off the press. Natural Product Reports, 28(4), pp. 659-662. (doi: 10.1039/C1NP90009A)
Hill, R.A. and Sutherland, A. (2011) Hot off the press. Natural Product Reports, 28(8), pp. 1345-1349. (doi: 10.1039/C1NP90027G)
Hill, R.A. and Sutherland, A. (2011) Hot off the press. Natural Product Reports, 28(2), pp. 182-185. (doi: 10.1039/C0NP90038A)
Hill, R.A. and Sutherland, A. (2011) Hot off the press. Natural Product Reports, 28(10), pp. 1621-1625. (doi: 10.1039/C1NP90035H)
McGonagle, F.I., Brown, L., Cooke, A. and Sutherland, A. (2011) Microwave-promoted tandem reactions for the synthesis of bicyclic γ-lactams. Tetrahedron Letters, 52(18), pp. 2330-2332. (doi: 10.1016/j.tetlet.2011.02.089)
Pimlott, S.L. and Sutherland, A. (2011) Molecular tracers for the PET and SPECT imaging of disease. Chemical Society Reviews, 40(1), pp. 149-162. (doi: 10.1039/B922628C)
Tavares, A.A.S., Jobson, N.K., Dewar, D. , Sutherland, A. and Pimlott, S.L. (2011) 123I-NKJ64: A novel single photon emission computed tomography radiotracer for imaging the noradrenaline transporter in brain. Synapse, 65(7), pp. 658-667. (doi: 10.1002/syn.20895)
2010
Tavares, A., Dewar, D. , Sutherland, A. and Pimlott, S. (2010) (R,S)-2-Iodo-reboxetine: development as a novel SPECT radiotracer for imaging the noradrenaline transporter in brain. NeuroImage, 52(S1), S115-S115. (doi: 10.1016/j.neuroimage.2010.04.094)
Drummond, L.J. and Sutherland, A. (2010) Asymmetric synthesis of allylic secondary alcohols: a new general approach for the preparation of α-amino acids. Tetrahedron, 66(29), pp. 5349-5356. (doi: 10.1016/j.tet.2010.05.066)
Hill, R.A. and Sutherland, A. (2010) Hot off the press. Natural Product Reports, 27(2), pp. 149-152. (doi: 10.1039/B926722K)
Hill, R.A. and Sutherland, A. (2010) Hot off the press. Natural Product Reports, 27(4), pp. 477-480. (doi: 10.1039/C003431M)
Hill, R.A. and Sutherland, A. (2010) Hot off the press. Natural Product Reports, 27(6), pp. 805-808. (doi: 10.1039/C005230M)
Hill, R.A. and Sutherland, A. (2010) Hot off the press. Natural Product Reports, 27(8), pp. 1110-1113. (doi: 10.1039/C005449F)
Hill, R.A. and Sutherland, A. (2010) Hot off the press. Natural Product Reports, 27(10), pp. 1381-1385. (doi: 10.1039/C0NP90017F)
Hill, R.A. and Sutherland, A. (2010) Hot off the press. Natural Product Reports, 27(12), pp. 1733-1736. (doi: 10.1039/C0NP90026E)
Kennedy, A.R., Kerr, W.J., Paterson, L.C. and Sutherland, A. (2010) A Tetrahydropentaleno[1,6a-a]naphthalen-4(2H)-one of Defined Relative Stereochemistry for Use Towards Agariblazeispirol C. Acta Crystallographica. Section D: Biological Crystallography, 66(9), 0473-0474. (doi: 10.1107/S0108270110031781)
McGonagle, F. I., Brown, L., Cooke, A. and Sutherland, A. (2010) A three-step tandem process for the synthesis of bicyclic gamma-lactams. Organic and Biomolecular Chemistry, 8(15), pp. 3418-3425. (doi: 10.1039/c004695g)
Stevenson, L., Tavares, A.A.S., Brunet, A., McGonagle, F.I., Dewar, D. , Pimlott, S.L. and Sutherland, A. (2010) New iodinated quinloine-2-varboxamides for SPECT imaging of the translocator protein. Bioorganic and Medicinal Chemistry Letters, 20(3), pp. 954-957. (doi: 10.1016/j.bmcl.2009.12.061)
Zaed, A.M. and Sutherland, A. (2010) Stereoselective synthesis of the bicyclic guanidine alkaloid (+)-monanchorin. Organic and Biomolecular Chemistry, 8(19), pp. 4394-4399. (doi: 10.1039/C0OB00219D)
2009
Swift, M.D., Donaldson, A. and Sutherland, A. (2009) Tandem aza-Claisen rearrangement and ring closing metathesis reactions: the stereoselective synthesis of functionalised carbocyclic amides. Tetrahedron Letters, 50(26), pp. 3241-3244. (doi: 10.1016/j.tetlet.2009.02.032)
Fowler, L.S., Ellis, D. and Sutherland, A. (2009) Synthesis of fluorescent enone derived α-amino acids. Organic and Biomolecular Chemistry, 7(20), pp. 4309-4316. (doi: 10.1039/b912782h)
Hill, R.A. and Sutherland, A. (2009) Hot off the press. Natural Product Reports, 26(2), pp. 151-154. (doi: 10.1039/B822940F)
Hill, R.A. and Sutherland, A. (2009) Hot off the press. Natural Product Reports, 26(4), pp. 461-464. (doi: 10.1039/B903591P)
Hill, R.A. and Sutherland, A. (2009) Hot off the press. Natural Product Reports, 26(6), pp. 725-728. (doi: 10.1039/B908225P)
Hill, R.A. and Sutherland, A. (2009) Hot off the press. Natural Product Reports, 26(8), pp. 973-976. (doi: 10.1039/B912059A)
Hill, R.A. and Sutherland, A. (2009) Hot off the press. Natural Product Reports, 26(10), pp. 1229-1233. (doi: 10.1039/B917244K)
Hill, R.A. and Sutherland, A. (2009) Hot off the press. Natural Product Reports, 26(12), pp. 1517-1520. (doi: 10.1039/B921623P)
Jobson, N., Crawford, A., Dewar, D., Pimlott, S. and Sutherland, A. (2009) Design and synthesis of (2R,3S)-iodoreboxetine analogues for SPECT imaging of the noradrenaline transporter. Bioorganic and Medicinal Chemistry Letters, 19(17), pp. 4996-4998. (doi: 10.1016/j.bmcl.2009.07.064)
Reid., C.M. and Sutherland, A. (2009) Synthesis of isotopically labeled α-amino acids. In: Hughes, A.B. (ed.) Amino Acids, Peptides and Proteins in Organic Chemistry. Vol. 1. Origins and Synthesis of Amino Acids. Wiley-VCH: Weinham, Germany. ISBN 9783527320967
Zaed, A.M., Swift, M.D. and Sutherland, A. (2009) A stereoselective synthesis of (+)-physoperuvine using a tandem aza-Claisen rearrangement and ring closing metathesis reaction. Organic and Biomolecular Chemistry, 7(13), pp. 2678-2680. (doi: 10.1039/b907341h)
2008
Hill, R.A. and Sutherland, A. (2008) Hot off the press. Natural Product Reports, 25(1), pp. 11-14. (doi: 10.1039/B719710C)
Hill, R.A. and Sutherland, A. (2008) Hot off the press. Natural Product Reports, 25(2), pp. 216-219. (doi: 10.1039/B803247P)
Hill, R.A. and Sutherland, A. (2008) Hot off the press. Natural Product Reports, 25(3), pp. 443-446. (doi: 10.1039/B806751C)
Hill, R.A. and Sutherland, A. (2008) Hot off the press. Natural Product Reports, 25(4), pp. 647-650. (doi: 10.1039/B810551K)
Hill, R.A. and Sutherland, A. (2008) Hot off the press. Natural Product Reports, 25(5), pp. 841-844. (doi: 10.1039/B814878N)
Hill, R.A. and Sutherland, A. (2008) Hot off the press. Natural Product Reports, 25(6), pp. 997-1000. (doi: 10.1039/b818366j)
Jobson, N., Crawford, A., Dewar, D., Pimlott, S. and Sutherland, A. (2008) New iodoreboxetine analogues for SPECT imaging of the noradrenaline transporter. Bioorganic and Medicinal Chemistry Letters, 18(18), pp. 4940-4943. (doi: 10.1016/j.bmcl.2008.08.041)
Jobson, N., Spike, R., Crawford, A., Dewar, D., Pimlott, S. and Sutherland, A. (2008) Stereoselective synthesis of (2S,3R)- and (2R,3S)-iodoreboxetine; potential SPECT imaging agents for the noradrenaline transporter. Organic and Biomolecular Chemistry, 6(13), pp. 2369-2376. (doi: 10.1039/b802819b)
Pimlott, S. L. , Stevenson, L., Wyper, D. J. and Sutherland, A. (2008) Rapid and efficient radiosynthesis of [I-123]I-PK11195, a single photon emission computed tomography tracer for peripheral benzodiazepine receptors. Nuclear Medicine and Biology, 35(5), pp. 537-542. (doi: 10.1016/j.nucmedbio.2008.02.013)
Swift, M. D. and Sutherland, A. (2008) Studies on the aza-Claisen rearrangement of 4,5-dihydroxylated allylic trichloroacetimidates: the stereoselective synthesis of (2R,3S)- and (2S,3S)-2-amino-3,4-dihydroxybutyric acids. Tetrahedron, 64(40), pp. 9521-9527. (doi: 10.1016/j.tet.2008.07.062)
2007
Stevenson, L., Pimlott, S. L. and Sutherland, A. (2007) A novel approach for the synthesis of the peripheral benzodiazepine receptor ligand, PK11195. Tetrahedron Letters, 48(40), pp. 7137-7139. (doi: 10.1016/j.tetlet.2007.07.203)
Jamieson, A. G. and Sutherland, A. (2007) Ether-directed palladium(II)-catalysed aza-Claisen rearrangements: studies on the origin of the directing effect. Tetrahedron, 63, pp. 2123-2131. (doi: 10.1016/j.tet.2006.12.067)
Bischoff, R., Hamilton, D., Jobson, N. and Sutherland, A. (2007) New approaches for the synthesis of isotopically labelled guanidine-derived amino acids and noradrenaline reuptake inhibitors. Journal of Labelled Compounds and Radiopharmaceuticals, 50, pp. 323-326. (doi: 10.1002/jlcr.1242)
Fanning, K. N. and Sutherland, A. (2007) A facile synthesis of (S)-gizzerosine, a potent agonist of the histamine H-2-receptor. Tetrahedron Letters, 48(48), pp. 8479-8481. (doi: 10.1016/j.tetlet.2007.09.165)
Jamieson, A. G. and Sutherland, A. (2007) Ether-directed, stereoselective aza-Claisen rearrangements: Synthesis of the piperidine alkaloid, alpha-conhydrine. Organic Letters, 9, pp. 1609-1611. (doi: 10.1021/ol070424z) (PMID:17371038)
Pillai, B., Cherney, M., Diaper, C., Sutherland, A. , Blanchard, J., Vederas, J. and James, M. (2007) Dynamics of catalysis revealed from the crystal structures of mutants of diaminopimelate epimerase. Biochemical and Biophysical Research Communications, 363, pp. 547-553. (doi: 10.1016/j.bbrc.2007.09.012)
Swift, M. D. and Sutherland, A. (2007) A tandem aza-Claisen rearrangement and ring closing metathesis reaction for the synthesis of cyclic allylic trichloroacetamides. Organic Letters, 9(25), pp. 5239-5242. (doi: 10.1021/ol702299c Univ Glasgow, Dept Chem, Glasgow G12 8QQ, Lanark, Scotland.)
Swift, M. and Sutherland, A. (2007) A stereoselective synthesis of (2R,3S)-2-amino-3,4-dihydroxybutyric acid using an ether directed aza-Claisen rearrangement. Tetrahedron Letters, 48, pp. 3771-3773. (doi: 10.1016/j.tetlet.2007.03.161)
Wilson, J., Henderson, G., Black, F., Sutherland, A., Ludwig, R., Vousden, K. and Robins, D. (2007) Synthesis of 5-deazaflavin derivatives and their activation of p53 in cells. Bioorganic and Medicinal Chemistry Letters, 15, pp. 77-86. (doi: 10.1016/j.bmc.2006.10.011)
Wilson, J., Giordani, F., Farrugia, L., Barrett, M., Robinsa, D. and Sutherland, A. (2007) Synthesis, characterisation and anti-protozoal activity of carbamate-derived polyazamacrocycles. Organic and Biomolecular Chemistry, 5, pp. 3651-3656. (doi: 10.1039/b710487a)
2006
Fanning, K. N., Jamieson, A. G. and Sutherland, A. (2006) Palladium(II)-catalysed rearrangement reactions. Current Organic Chemistry, 10(9), pp. 1007-1020. (doi: 10.2174/138527206777435490)
Jamieson, A. G. and Sutherland, A. (2006) Scope and limitations of ether-directed, metal-catalysed aza-Claisen rearrangements; improved stereoselectivity using non-coordinating solvents. Organic and Biomolecular Chemistry, 4, pp. 2932-2937. (doi: 10.1039/b607014k) (PMID:16855742)
Pillai, B., Cherney, M., Diaper, C., Sutherland, A. , Blanchard, J., Vederas, J. and James, M. (2006) Structural insights into stereochemical inversion by diaminopimelate epimerase: An antibacterial drug target. Proceedings of the National Academy of Sciences of the United States of America, 103(23), pp. 8668-8673. (doi: 10.1073/pnas.0602537103)
Swift, M. and Sutherland, A. (2006) Stereocontrol of palladium(II)-catalysed aza-Claisen rearrangements using a combination of 1,3-allylic strain and a solvent mediated directing effect. Organic and Biomolecular Chemistry, 4, pp. 3889-3891. (doi: 10.1039/b613271e)
2005
Bischoff, R., McDonald, N. and Sutherland, A. (2005) A highly efficient, asymmetric synthesis of blastidic acid: the beta-amino acid component of the antibiotic, (+)-blasticidin S. Tetrahedron Letters, 46, pp. 7147-7149. (doi: 10.1016/j.tetlet.2005.08.096)
Diaper, C., Sutherland, A. , Pillai, B., James, M., Semchuk, P., Blanchard, J. and Vederas, J. (2005) The stereoselective synthesis of aziridine analogues of diaminopimelic acid (DAP) and their interaction with dap epimerase. Organic and Biomolecular Chemistry, 3, pp. 4402-4411. (doi: 10.1039/b513409a)
Fanning, K. N., Jamieson, A. G. and Sutherland, A. (2005) Stereoselective beta-hydroxy-alpha-amino acid synthesis via an ether-directed, palladium-catalysed aza-Claisen rearrangement. Organic and Biomolecular Chemistry, 3, pp. 3749-3756. (doi: 10.1039/b510808j) (PMID:16211111)
Jamieson, A. G. and Sutherland, A. (2005) A highly stereoselective ether directed palladium catalysed aza-Claisen rearrangement. Organic and Biomolecular Chemistry, 3, pp. 735-736. (PMID:15731857)
2004
Hamilton, D. and Sutherland, A. (2004) A flexible approach for the synthesis of selectively labelled L-arginine. Tetrahedron Letters, 45, pp. 5739-5741. (doi: 10.1016/j.tetlet.2004.05.096)
Jamieson, A. G. , Sutherland, A. and Willis, C. L. (2004) The first enantioselective synthesis of the amino acid, (2S,3S,4R)-gamma-hydroxyisoleucine using a palladium(II) catalysed 3,3-sigmatropic rearrangement. Organic and Biomolecular Chemistry, 2, pp. 808-809. (doi: 10.1039/b401076k)
Articles
Waddell, L. J.N., Okunade, O. A.M., Dodds, A. C., Lok, M. C.H., Khanizeman, R. N. and Sutherland, A. (2025) Iron-catalyzed thioarylation of arenes using saccharin-derived reagents. Journal of Organic Chemistry, (Accepted for Publication)
Zeng, L., Marshall, O., McGrory, R., Clarke, R. , Brown, R. J., Kadodwala, M. , Thomson, A. R. and Sutherland, A. (2025) Synthesis of fluorescent dibenzofuran α-amino acids: conformationally rigid analogues of tyrosine. Organic Letters, (Accepted for Publication)
Marshall, O., McGrory, R., Songsri, S., Thomson, A. R. and Sutherland, A. (2025) Expedient discovery of fluorogenic amino acid-based probes via one-pot palladium-catalysed arylation of tyrosine. Chemical Science, (Accepted for Publication)
Morgan, T. E. F., Grant, E. K., Shaw, R. C., Waddell, L. J. N., Henry, M. C., McErlain, H., Alcaide-Corral, C. J., Pimlott, S. L. , Tavares, A. A. S. and Sutherland, A. (2025) Synthesis and evaluation of 6-arylaminobenzamides as positron emission tomography imaging ligands for the sphingosine-1-phosphate-5 receptor. RSC Medicinal Chemistry, (doi: 10.1039/D4MD00929K) (Early Online Publication)
Chaubey, S. K. et al. (2024) Ultrasensitive Raman detection of biomolecular conformation at the attomole scale using chiral nanophotonics. Small, 20(45), 2404536. (doi: 10.1002/smll.202404536)
Burianova, V. K., Mcerlain, H. and Sutherland, A. (2024) Transition metal-mediated radiohalogenation using aryl boron reagents. Synthesis, (doi: 10.1055/s-0043-1775408) (Early Online Publication)
Songsri, S., McErlain, H. and Sutherland, A. (2024) Stereoselective synthesis of meso- and L,L-diaminopimelic acids from enone-derived α-amino acids. Journal of Organic Chemistry, 89(14), pp. 10363-10370. (doi: 10.1021/acs.joc.4c00916) (PMID:38955772) (PMCID:PMC11267594)
Riley, L. M. , Marshall, O., Harkiss, A. H., Senn, H. M. and Sutherland, A. (2024) Synthesis of β-pyridyl α-amino acids: conformationally sensitive charge transfer-based fluorophores. Organic Letters, 26(25), pp. 5391-5395. (doi: 10.1021/acs.orglett.4c01951) (PMID:38865167) (PMCID:PMC11217948)
Clarke, R. , Zeng, L., Atkinson, B. C., Kadodwala, M. , Thomson, A. R. and Sutherland, A. (2024) Fluorescent carbazole-derived α-amino acids; structural mimics of tryptophan. Chemical Science, 15(16), pp. 5944-5949. (doi: 10.1039/D4SC01173B) (PMID:38665535) (PMCID:PMC11040653)
Hill, R. A. and Sutherland, A. (2024) Hot off the press. Natural Product Reports, 41(4), pp. 520-524. (doi: 10.1039/d4np90015d) (PMID:38616726)
Knyzeliene, A., MacAskill, M. G., Alcaide-Corral, C. J., Morgan, T. E., Henry, M. C., Lucatelli, C., Pimlott, S. L. , Sutherland, A. and Tavares, A. A.S. (2024) [18F]LW223 has low non-displaceable binding in murine brain, enabling high sensitivity TSPO PET imaging. Journal of Cerebral Blood Flow and Metabolism, 44(3), pp. 397-406. (doi: 10.1177/0271678x231205661) (PMID:37795635) (PMCID:PMC10870961)
McErlain, H., Andrews, M. J., Watson, A. J.B., Pimlott, S. L. and Sutherland, A. (2024) Ligand-enabled copper-mediated radioiodination of arenes. Organic Letters, 26(7), pp. 1528-1532. (doi: 10.1021/acs.orglett.4c00356) (PMID:38335124) (PMCID:PMC10897930)
Hill, R. A. and Sutherland, A. (2024) Hot off the press. Natural Product Reports, 41(2), pp. 157-161. (doi: 10.1039/d4np90005g) (PMID:38318713)
Waddell, L. J.N., Wilson, C. and Sutherland, A. (2024) Trifluoromethylthiolation of Arenes using Lewis acid and Lewis base dual catalysis. Journal of Organic Chemistry, 89(2), pp. 1275-1284. (doi: 10.1021/acs.joc.3c02571) (PMID:38156642)
Dodds, A. C., Sansom, H. G., Magennis, S. W. and Sutherland, A. (2023) Synthesis of Thiazoloindole α‑Amino Acids: Chromophores Amenable to One- and Two-Photon Induced Fluorescence. Organic Letters, 25(49), pp. 8942-8946. (doi: 10.1021/acs.orglett.3c03851) (PMID:38055619) (PMCID:PMC10729019)
Dodds, A. C., Waddell, L. J.N. and Sutherland, A. (2023) Regioselective functionalization of arenes using iron triflimide catalysis. Synlett, 34(16), pp. 1852-1865. (doi: 10.1055/s-0042-1751445)
McGrory, R., Clarke, R. , Marshall, O. and Sutherland, A. (2023) Fluorescent α-amino acids via Heck–Matsuda reactions of phenylalanine-derived arenediazonium salts. Organic and Biomolecular Chemistry, 21(34), pp. 6932-6939. (doi: 10.1039/d3ob01096a) (PMID:37580965)
Songsri, S., Harkiss, A. H. and Sutherland, A. (2023) Synthesis and photophysical properties of charge-transfer based pyrimidine-derived ∝-amino acids. Journal of Organic Chemistry, 88(18), pp. 13214-13224. (doi: 10.1021/acs.joc.3c01437) (PMID:37621156) (PMCID:PMC10507667)
McGrory, R., Morgan, D. C., Jamieson, A. G. and Sutherland, A. (2023) Rotamer-controlled dual emissive α-amino acids. Organic Letters, 25(31), pp. 5844-5849. (doi: 10.1021/acs.orglett.3c02112) (PMID:37506290) (PMCID:PMC10425982)
Waddell, L. J.N., Senkans, M. R. and Sutherland, A. (2023) Regioselective C–H thiocyanation of arenes by iron(III) chloride catalysis. Journal of Organic Chemistry, 88(11), pp. 7208-7218. (doi: 10.1021/acs.joc.3c00454) (PMID:37158540)
Hill, R. A. and Sutherland, A. (2023) Hot off the press. Natural Product Reports, 40(4), pp. 761-765. (doi: 10.1039/D3NP90016A) (PMID:37038828)
Riley, L., Mclay, T. N. and Sutherland, A. (2023) Synthesis and fluorescent properties of alkynyl- and alkenyl-fused benzotriazole-derived α-amino acids. Journal of Organic Chemistry, 88(4), pp. 2453-2463. (doi: 10.1021/acs.joc.2c02886) (PMID:36749161) (PMCID:PMC9942204)
Hill, R. A. and Sutherland, A. (2023) Hot off the press. Natural Product Reports, 40(2), pp. 223-227. (doi: 10.1039/D3NP90007J) (PMID:36756783)
Hill, R. A. and Sutherland, A. (2022) Hot off the press. Natural Product Reports, 39(12), pp. 2209-2214. (doi: 10.1039/D2NP90043B) (PMID:36412123)
Tabouillot, V. et al. (2022) Near-field probing of optical superchirality with plasmonic circularly polarized luminescence for enhanced bio-detection. ACS Photonics, 9(11), pp. 3617-3624. (doi: 10.1021/acsphotonics.2c01073) (PMID:36411820)
McErlain, H., McLean, E. B., Morgan, T. E. F., Burianova, V. K., Tavares, A. A. S. and Sutherland, A. (2022) Organocatalytic asymmetric synthesis of SynVesT-1, A synaptic density positron emission tomography imaging agent. Journal of Organic Chemistry, 87(21), pp. 14443-14451. (doi: 10.1021/acs.joc.2c01895) (PMID:36222243)
Hill, R. A. and Sutherland, A. (2022) Hot off the press. Natural Product Reports, 39(10), pp. 1904-1909. (doi: 10.1039/D2NP90034C)
Waddell, L., Henry, M., Mostafa, M. and Sutherland, A. (2022) One-pot synthesis of diaryl sulfonamides using an iron and copper catalyzed aryl C–H amidation process. Synthesis, 54(20), pp. 4551-4560. (doi: 10.1055/a-1884-6988)
Hill, R. A. and Sutherland, A. (2022) Hot off the press. Natural Product Reports, 39(8), pp. 1539-1543. (doi: 10.1039/D2NP90026B) (PMID:35929527)
Dodds, A. C., Puddu, S. and Sutherland, A. (2022) Thioarylation of anilines using dual catalysis: two-step synthesis of phenothiazines. Organic and Biomolecular Chemistry, 20(28), pp. 5602-5614. (doi: 10.1039/D2OB01082H) (PMID:35796590)
Hill, R. A. and Sutherland, A. (2022) Hot off the press. Natural Product Reports, 39(6), pp. 1117-1121. (doi: 10.1039/D2NP90019J)
Hill, R. A. and Sutherland, A. (2022) Hot off the press. Natural Product Reports, 39(4), pp. 737-741. (doi: 10.1039/D2NP90011D) (PMID:35362487)
Dodds, A. C. and Sutherland, A. (2022) Synthesis of phenoxathiins using an iron-catalysed C–H thioarylation. Organic and Biomolecular Chemistry, 20(8), pp. 1738-1748. (doi: 10.1039/D2OB00022A) (PMID:35142330)
Hill, R. A. and Sutherland, A. (2022) Hot off the press. Natural Product Reports, 39(2), pp. 217-221. (doi: 10.1039/D2NP90004A)
Mcerlain, H., Riley, L. M. and Sutherland, A. (2021) Palladium-catalyzed C—P bond-forming reactions of aryl nonaflates accelerated by iodide. Journal of Organic Chemistry, 86(23), pp. 17036-17049. (doi: 10.1021/acs.joc.1c02172) (PMID:34726917)
Hill, R. A. and Sutherland, A. (2021) Hot off the press. Natural Product Reports, 38(12), pp. 2139-2144. (doi: 10.1039/D1NP90046C) (PMID:34851342)
MacAskill, M. G., Wimberley, C., Morgan, T. E. F., Alcaide‑Corral, C. J., Newby, D. E., Lucatelli, C., Sutherland, A. , Pimlott, S. L. and Tavares, A. A. S. (2021) Modelling [18F]LW223 PET data using simplified imaging protocols for quantification of TSPO expression in the rat heart and brain. European Journal of Nuclear Medicine and Molecular Imaging, 49, pp. 137-145. (doi: 10.1007/S00259-021-05482-1) (PMID:34338808) (PMCID:PMC8712302)
Morgan, T. E.F., Riley, L. M., Tavares, A. A.S. and Sutherland, A. (2021) Automated Radiosynthesis of cis- and trans-4-[18F]Fluoro-L-proline using [18F]Fluoride. Journal of Organic Chemistry, 86(20), pp. 14054-14060. (doi: 10.1021/acs.joc.1c00755) (PMID:33913318) (PMCID:PMC8524414)
Hill, R. A. and Sutherland, A. (2021) Hot off the press. Natural Product Reports, 38(10), pp. 1715-1719. (doi: 10.1039/D1NP90037D)
Hill, R. A. and Sutherland, A. (2021) Hot off the press. Natural Product Reports, 38(8), pp. 1418-1422. (doi: 10.1039/D1NP90030G)
Hill, R. A. and Sutherland, A. (2021) Hot off the press. Natural Product Reports, 38(6), pp. 1053-1057. (doi: 10.1039/D1NP90020J)
Dodds, A. C. and Sutherland, A. (2021) Regioselective C-H thioarylation of electron-rich arenes by iron(III) triflimide catalysis. Journal of Organic Chemistry, 86(8), pp. 5922-5932. (doi: 10.1021/acs.joc.1c00448) (PMID:33783222)
Hill, R. A. and Sutherland, A. (2021) Hot off the press. Natural Product Reports, 38(4), pp. 677-681. (doi: 10.1039/D1NP90013G)
MacAskill, M. G. et al. (2021) Quantification of macrophage-driven inflammation during myocardial infarction with 18F-LW223, a novel TSPO radiotracer with binding independent of the rs6971 human polymorphism. Journal of Nuclear Medicine, 62(4), pp. 536-544. (doi: 10.2967/jnumed.120.243600) (PMID:32859708) (PMCID:PMC8049364)
Hill, R. A. and Sutherland, A. (2021) Hot off the press. Natural Product Reports, 38(2), pp. 287-291. (doi: 10.1039/D1NP90005F)
McGrory, R., Faggyas, R. and Sutherland, A. (2021) One-pot synthesis of N-substituted benzannulated triazoles via stable arene diazonium salts. Organic and Biomolecular Chemistry, 19(27), pp. 6127-6140. (doi: 10.1039/D1OB00968K) (PMID:34179913)
Hill, R. A. and Sutherland, A. (2020) Hot off the press. Natural Product Reports, 37(12), pp. 1556-1560. (doi: 10.1039/D0NP90047H)
Hill, R. A. and Sutherland, A. (2020) Hot off the press. Natural Product Reports, 37(10), pp. 1294-1299. (doi: 10.1039/D0NP90037K)
Hill, R. A. and Sutherland, A. (2020) Hot off the press. Natural Product Reports, 37(8), pp. 1038-1042. (doi: 10.1039/D0NP90029J)
Dubost, E., Mcerlain, H., Babin, V., Sutherland, A. and Cailly, T. (2020) Recent advances in synthetic methods for radioiodination. Journal of Organic Chemistry, 85(13), pp. 8300-8310. (doi: 10.1021/acs.joc.0c00644) (PMID:32369696)
Hill, R. A. and Sutherland, A. (2020) Hot off the press. Natural Product Reports, 37(6), pp. 747-751. (doi: 10.1039/D0NP90022B)
Sood, D. E., Champion, S., Dawson, D. M., Chabbra, S., Bode, B. E., Sutherland, A. and Watson, A. J. B. (2020) Deoxyfluorination with CuF2: enabled by using a Lewis base activating group. Angewandte Chemie (International Edition), 59(22), pp. 8460-8463. (doi: 10.1002/anie.202001015) (PMID:32109331)
Henry, M. C., Abbinante, V. M. and Sutherland, A. (2020) Iron-catalyzed regioselective synthesis of 2-arylbenzoxazoles and 2-arylbenzothiazoles via alternative reaction pathways. European Journal of Organic Chemistry, 2020(19), pp. 2819-2826. (doi: 10.1002/ejoc.202000014)
Henry, M. C. and Sutherland, A. (2020) Synthesis of benzo[b]furans by intramolecular C–O bond formation using iron and copper catalysis. Organic Letters, 22(7), pp. 2766-2770. (doi: 10.1021/acs.orglett.0c00754) (PMID:32186389) (PMCID:PMC7146889)
Hill, R. A. and Sutherland, A. (2020) Hot off the press. Natural Product Reports, 37(4), pp. 472-476. (doi: 10.1039/D0NP90014A)
Hill, R. A. and Sutherland, A. (2020) Hot off the press. Natural Product Reports, 37(2), pp. 145-149. (doi: 10.1039/D0NP90004D)
Bell, J. D., Harkiss, A. H., Nobis, D., Malcolm, E., Knuhtsen, A., Wellaway, C. R., Jamieson, A. G. , Magennis, S. W. and Sutherland, A. (2020) Conformationally rigid pyrazoloquinazoline α-amino acids: one- and two-photon induced fluorescence. Chemical Communications, 56(12), pp. 1887-1890. (doi: 10.1039/C9CC09064A) (PMID:31956866)
Hill, R. A. and Sutherland, A. (2019) Hot off the press. Natural Product Reports, 36(12), pp. 1614-1618. (doi: 10.1039/C9NP90045D) (PMID:31777890)
Hill, R. A. and Sutherland, A. (2019) Hot off the press. Natural Product Reports, 36(10), pp. 1378-1382. (doi: 10.1039/C9NP90041A) (PMID:31538642)
Faggyas, R. J., Sloan, N. L., Buijs, N. and Sutherland, A. (2019) Synthesis of structurally diverse benzotriazoles via rapid diazotization and intramolecular cyclization of 1,2-aryldiamines. European Journal of Organic Chemistry, 2019(31-32), pp. 5344-5353. (doi: 10.1002/ejoc.201900463)
Hill, R. A. and Sutherland, A. (2019) Hot off the press. Natural Product Reports, 36(8), pp. 1039-1043. (doi: 10.1039/C9NP90031D) (PMID:31332420)
Bell, J. D., Morgan, T. E.F., Buijs, N., Harkiss, A. H., Wellaway, C. R. and Sutherland, A. (2019) Synthesis and photophysical properties of benzotriazole-derived unnatural α -amino acids. Journal of Organic Chemistry, 84(16), pp. 10436-10448. (doi: 10.1021/acs.joc.9b01685) (PMID:31340638)
MacAskill, M. G. et al. (2019) Kinetic modelling and quantification bias in small animal PET studies with [18F]AB5186, a novel 18 kDa translocator protein radiotracer. PLoS ONE, 14(5), e0217515. (doi: 10.1371/journal.pone.0217515) (PMID:31150436) (PMCID:PMC6544349)
Henry, M. C., McGrory, R., Faggyas, R. J., Mostafa, M. A.B. and Sutherland, A. (2019) One-pot ortho-amination of aryl C-H bonds using consecutive iron and copper catalysis: late-stage structural diversification of 3,4-dihydroquinolin-2-one. Organic and Biomolecular Chemistry, 17(18), pp. 4629-4639. (doi: 10.1039/C9OB00712A) (PMID:31020305)
Hill, R. A. and Sutherland, A. (2019) Hot off the press. Natural Product Reports, 36(6), pp. 850-854. (doi: 10.1039/C9NP90019E)
Molloy, J. J., O'Rourke, K., Frias, C. P., Sloan, N., West, M. J., Pimlott, S. L. , Sutherland, A. and Watson, A. J.B. (2019) Mechanism of Cu-catalyzed aryl boronic acid halodeboronation using electrophilic halogen: development of a base-catalyzed iododeboronation for radiolabeling applications. Organic Letters, 21(7), pp. 2488-2492. (doi: 10.1021/acs.orglett.9b00942) (PMID:30908055)
Hill, R. A. and Sutherland, A. (2019) Hot off the press. Natural Product Reports, 36(4), pp. 556-560. (doi: 10.1039/C9NP90010A)
Harkiss, A. H., Bell, J. D., Knuhtsen, A., Jamieson, A. G. and Sutherland, A. (2019) Synthesis and fluorescent properties of β-pyridyl α-amino acids. Journal of Organic Chemistry, 84(5), pp. 2879-2890. (doi: 10.1021/acs.joc.9b00036) (PMID:30726078)
Hill, R. A. and Sutherland, A. (2019) Hot off the press. Natural Product Reports, 36(2), pp. 258-262. (doi: 10.1039/C9NP90001B) (PMID:30667456)
Henry, M. C., Senn, H. M. and Sutherland, A. (2019) Synthesis of functionalized indolines and dihydrobenzofurans by iron and copper catalyzed aryl C-N and C-O bond formation. Journal of Organic Chemistry, 84(1), pp. 346-364. (doi: 10.1021/acs.joc.8b02888) (PMID:30520304)
Sutherland, A. (2019) Radiohalogenation of organic compounds: practical considerations and challenges for molecular imaging. Synthesis, 51(23), pp. 4368-4373. (doi: 10.1055/s-0037-1611885)
Hill, R. A. and Sutherland, A. (2018) Hot off the press. Natural Product Reports, 35(12), pp. 1236-1240. (doi: 10.1039/C8NP90046A) (PMID:30474086)
Faggyas, R. J., Grace, M., Williams, L. and Sutherland, A. (2018) Multibond forming tandem reactions of anilines via stable aryl diazonium salts: one-pot synthesis of 3,4-dihydroquinolin-2-ones. Journal of Organic Chemistry, 83(20), pp. 12595-12608. (doi: 10.1021/acs.joc.8b01910) (PMID:30230840)
Hill, R. A. and Sutherland, A. (2018) Hot off the press. Natural Product Reports, 35(10), pp. 1024-1028. (doi: 10.1039/C8NP90032A) (PMID:30209473)
Bell, J. D., Harkiss, A. H., Wellaway, C. R. and Sutherland, A. (2018) Stereoselective synthesis of 2,6-trans-4-oxopiperidines using an acid-mediated 6-endo-trig cyclisation. Organic and Biomolecular Chemistry, 16(35), pp. 6410-6422. (doi: 10.1039/C8OB01363B) (PMID:30011344)
Hill, R. A. and Sutherland, A. (2018) Hot off the press. Natural Product Reports, 35(8), pp. 702-706. (doi: 10.1039/C8NP90024H) (PMID:30058659)
O'Rourke, K., Johnstone, E. S., Becker, H. M., Pimlott, S. L. and Sutherland, A. (2018) Exploring the functionalisation of the thieno[2,3-d]pyrimidinedione core: late stage access to highly substituted 5-carboxamide-6-aryl scaffolds. Tetrahedron, 74(30), pp. 4086-4094. (doi: 10.1016/j.tet.2018.06.019)
Hill, R. A. and Sutherland, A. (2018) Hot off the press. Natural Product Reports, 35(6), pp. 496-500. (doi: 10.1039/c8np90015a) (PMID:29878011)
Gibson, E. K. , Callison, J., Winfield, J. M., Sutherland, A. , Carr, R. H., Eaglesham, A., Parker, S. F. and Lennon, D. (2018) Spectroscopic characterization of model compounds, reactants, and byproducts connected with an isocyanate production chain. Industrial and Engineering Chemistry Research, 57(22), pp. 7355-7362. (doi: 10.1021/acs.iecr.8b00853)
Zmuda, F., Blair, A., Liuzzi, M. C., Malviya, G. , Chalmers, A. J. , Lewis, D., Sutherland, A. and Pimlott, S. L. (2018) An 18F-labeled poly(ADP-ribose) polymerase positron emission tomography imaging agent. Journal of Medicinal Chemistry, 61(9), pp. 4103-4114. (doi: 10.1021/acs.jmedchem.8b00138) (PMID:29630818) (PMCID:PMC6007963)
Hill, R. A. and Sutherland, A. (2018) Hot off the press. Natural Product Reports, 35, pp. 298-302. (doi: 10.1039/c8np90008f) (PMID:29532849)
Hill, R. A. and Sutherland, A. (2018) Hot off the press. Natural Product Reports, 35(2), pp. 132-136. (doi: 10.1039/c7np90051a) (PMID:29350723)
Webster, S., O'Rourke, K. M., Fletcher, C., Pimlott, S. L. , Sutherland, A. and Lee, A.-L. (2018) Rapid iododeboronation with and without gold catalysis: application to radiolabelling of arenes. Chemistry: A European Journal, 24(4), pp. 937-943. (doi: 10.1002/chem.201704534) (PMID:29105856) (PMCID:PMC5814724)
Harkiss, A. H. and Sutherland, A. (2018) Access to 2,6-disubstituted 4-oxopiperidines using a 6-endo-trig cyclization: stereoselective synthesis of spruce alkaloid and (+)-241D. Journal of Organic Chemistry, 83(1), pp. 535-542. (doi: 10.1021/acs.joc.7b02799) (PMID:29218988)
Hill, R. A. and Sutherland, A. (2017) Hot off the press. Natural Product Reports, 34(12), pp. 1340-1344. (doi: 10.1039/c7np90044a) (PMID:29090285)
Faggyas, R. J., Calder, E. D.D., Wilson, C. and Sutherland, A. (2017) One-pot asymmetric synthesis of alkylidene 1-alkylindan-1-ols using Brønsted acid and palladium catalysis. Journal of Organic Chemistry, 82(21), pp. 11585-11593. (doi: 10.1021/acs.joc.7b02287) (PMID:28985675)
Sloan, N. L., Luthra, S. K., McRobbie, G., Pimlott, S. L. and Sutherland, A. (2017) One-pot radioiodination of aryl amines via stable diazonium salts: preparation of 125I-imaging agents. Chemical Communications, 53(80), pp. 11008-11011. (doi: 10.1039/C7CC06211G) (PMID:28849815)
Hill, R. A. and Sutherland, A. (2017) Hot off the press. Natural Product Reports, 34(10), pp. 1180-1184. (doi: 10.1039/c7np90040f) (PMID:28952651)
Henry, M. C., Sutherland, A. and Mostafa, M. A.B. (2017) Recent advances in transition-metal-catalyzed, directed Aryl C-H/N-H cross coupling reactions. Synthesis, 49(20), pp. 4586-4598. (doi: 10.1055/s-0036-1588536)
Hill, R. A. and Sutherland, A. (2017) Hot off the press. Natural Product Reports, 34(8), pp. 940-944. (doi: 10.1039/c7np90028g) (PMID:28717803)
Mostafa, M. A.B., Bowley, R. M., Racys, D. T., Henry, M. C. and Sutherland, A. (2017) Iron(III)-catalyzed chlorination of activated arenes. Journal of Organic Chemistry, 82(14), pp. 7529-7537. (doi: 10.1021/acs.joc.7b01225) (PMID:28661157)
Hill, R. A. and Sutherland, A. (2017) Hot off the press. Natural Product Reports, 34(6), pp. 566-570. (doi: 10.1039/c7np90017a) (PMID:28497154)
MacAskill, M., Zmuda, F., Lucatelli, C., Dweck, M., Gray, G., Newby, D., Sutherland, A. , Pimlott, S. and Tavares, A. (2017) Binding affinity profiles of isoquinoline carboxamide and phenoxyphenyl acetamide-based TSPO PET ligands in human brain and heart. Journal of Nuclear Medicine, 58(suppl1), p. 478.
Mostafa, M., McMillan, A. E. and Sutherland, A. (2017) Structural diversification of the aminobicyclo[4.3.0]nonane skeleton using alkynylsilyl-derived allylic trichloroacetimidates. Organic and Biomolecular Chemistry, 15(14), pp. 3035-3045. (doi: 10.1039/C7OB00456G) (PMID:28304410)
Hill, R. A. and Sutherland, A. (2017) Hot off the press. Natural Product Reports, 34(4), pp. 338-342. (doi: 10.1039/c7np90009k) (PMID:28322409)
Hill, R. A. and Sutherland, A. (2017) Hot off the press. Natural Product Reports, 34(2), pp. 130-134. (doi: 10.1039/c6np90051h) (PMID:28079908)
Sloan, N. L., Luthra, S. K., McRobbie, G., Pimlott, S. L. and Sutherland, A. (2017) Late stage iodination of biologically active agents using a one-pot process from aryl amines. RSC Advances, 7(86), pp. 54881-54891. (doi: 10.1039/C7RA11860K)
Mostafa, M. A.B., Calder, E. D.D., Sutherland, A. and Racys, D. T. (2016) Intermolecular Aryl C-H amination using sequential iron and copper catalysis. Chemistry: A European Journal, 23(5), pp. 1044-1047. (doi: 10.1002/chem.201605671) (PMID:27918637)
Hill, R. A. and Sutherland, A. (2016) Hot off the press. Natural Product Reports, 33(12), pp. 1352-1356. (doi: 10.1039/c6np90047j) (PMID:27785514)
Sharif, S. A.I., Calder, E. D.D., Harkiss, A., Maduro, M. and Sutherland, A. (2016) Synthesis of allylic amide functionalized 2H-chromenes and coumarins using a one-pot overman rearrangement and gold(I)-catalyzed hydroarylation. Journal of Organic Chemistry, 81(20), pp. 9810-9819. (doi: 10.1021/acs.joc.6b01881) (PMID:27680202)
Harkiss, A. and Sutherland, A. (2016) Recent advances in the synthesis and application of fluorescent α-amino acids. Organic and Biomolecular Chemistry, 14(38), pp. 8911-8921. (doi: 10.1039/C6OB01715K) (PMID:27714204)
Hill, R. A. and Sutherland, A. (2016) Correction: Hot off the press. Natural Product Reports, 33(10), p. 1239. (doi: 10.1039/c6np90040b) (PMID:27714075)
Hill, R. A. and Sutherland, A. (2016) Hot off the press. Natural Product Reports, 33(10), pp. 1126-1130. (doi: 10.1039/c6np90039a) (PMID:27785514)
Sharif, S. A.I., Calder, E. D.D., Delolo, F. G. and Sutherland, A. (2016) Synthesis of 5-Amino-2,5-dihydro-1H-benzo[b]azepines using a one-pot multibond forming process. Journal of Organic Chemistry, 81(15), pp. 6697-6706. (doi: 10.1021/acs.joc.6b01357) (PMID:27414232)
Hill, R. A. and Sutherland, A. (2016) Hot off the press. Natural Product Reports, 33(8), pp. 915-919. (doi: 10.1039/c6np90030e)
Hill, R. A. and Sutherland, A. (2016) Hot off the press. Natural Product Reports, 33(6), pp. 742-746. (doi: 10.1039/C6NP90022D) (PMID:27173803)
Hill, R. A. and Sutherland, A. (2016) Hot off the press. Natural Product Reports, 33(4), pp. 530-534. (doi: 10.1039/c6np90012g)
Mostafa, M. A.B., Grafton, M. W., Wilson, C. and Sutherland, A. (2016) A one-pot, three-step process for the diastereoselective synthesis of aminobicyclo[4.3.0]nonanes using consecutive palladium(II)- and ruthenium(II)-catalysis. Organic and Biomolecular Chemistry, 14(14), pp. 3284-3297. (doi: 10.1039/C6OB00165C) (PMID:26932788)
Racys, D. T., Sharif, S. A.I., Pimlott, S. L. and Sutherland, A. (2016) Silver(I)-catalyzed iodination of Arenes: Tuning the Lewis acidity of N-iodosuccinimide activation. Journal of Organic Chemistry, 81(3), pp. 772-780. (doi: 10.1021/acs.joc.5b02761) (PMID:26795534)
Hill, R. A. and Sutherland, A. (2016) Hot off the press. Natural Product Reports, 33(2), pp. 122-126. (doi: 10.1039/c5np90052b)
Hill, R. A. and Sutherland, A. (2015) Hot off the press. Natural Product Reports, 32(12), pp. 1612-1616. (doi: 10.1039/c5np90047f)
Zmuda, F., Malviya, G. , Blair, A., Boyd, M., Chalmers, A. J. , Sutherland, A. and Pimlott, S. L. (2015) Synthesis and evaluation of a radioiodinated tracer with specificity for poly(ADP-ribose) polymerase-1 (PARP-1) in vivo. Journal of Medicinal Chemistry, 58(21), pp. 8683-8693. (doi: 10.1021/acs.jmedchem.5b01324) (PMID:26469301)
Racys, D. T., Warrilow, C. E., Pimlott, S. L. and Sutherland, A. (2015) Highly regioselective iodination of arenes via iron(III)-catalyzed activation of N-iodosuccinimide. Organic Letters, 17(19), pp. 4782-4785. (doi: 10.1021/acs.orglett.5b02345) (PMID:26394175)
Hill, R. A. and Sutherland, A. (2015) Hot off the press. Natural Product Reports, 32(10), pp. 1364-1368. (doi: 10.1039/c5np90039e)
Hill, R. A. and Sutherland, A. (2015) Hot off the press. Natural Product Reports, 32(8), pp. 1165-1169. (doi: 10.1039/c5np90032h)
Hill, R. A. and Sutherland, A. (2015) Hot off the press. Natural Product Reports, 32(6), pp. 760-764. (doi: 10.1039/c5np90021b)
Calder, E. D.D. and Sutherland, A. (2015) Enantioselective synthesis of 3-methyleneindan-1-ols via a one-pot allylboration–Heck reaction of 2-bromobenzaldehydes. Organic Letters, 17(10), pp. 2514-2517. (doi: 10.1021/acs.orglett.5b01047) (PMID:25933177)
Calder, E. D.D., Sharif, S. A.I., McGonagle, F. I. and Sutherland, A. (2015) One-pot synthesis of 5-amino-2,5-dihydro-1-benzoxepines: access to pharmacologically active heterocyclic scaffolds. Journal of Organic Chemistry, 80(9), pp. 4683-4696. (doi: 10.1021/acs.joc.5b00583) (PMID:25847814)
Gilfillan, L., Artschwager, R., Harkiss, A. H., Liskamp, R. M.J. and Sutherland, A. (2015) Synthesis of pyrazole containing α-amino acids via a highly regioselective condensation/aza-Michael reaction of β-aryl α,β-unsaturated ketones. Organic and Biomolecular Chemistry, 13(15), pp. 4514-4523. (doi: 10.1039/C5OB00364D) (PMID:25774874)
Hill, R. A. and Sutherland, A. (2015) Hot off the press. Natural Product Reports, 32(4), pp. 512-516. (doi: 10.1039/c5np90013a)
Hill, R. A. and Sutherland, A. (2015) Hot off the press. Natural Product Reports, 32(2), pp. 111-115. (doi: 10.1039/c4np90046d)
Reid, C. M., Fanning, K. N., Fowler, L. S. and Sutherland, A. (2015) Synthesis and reactivity of 4-oxo-5-trimethylsilanyl derived α-amino acids. Tetrahedron, 71(2), pp. 245-251. (doi: 10.1016/j.tet.2014.11.059)
Blair, A., Zmuda, F., Malviya, G. , Chalmers, A. J. , Dewar, D. , Pimlott, S. L. and Sutherland, A. (2015) A novel 18F-labelled high affinity agent for PET imaging of the translocator protein. Chemical Science, 6(8), pp. 4772-4777. (doi: 10.1039/C5SC01647A)
Hill, R. A. and Sutherland, A. (2014) Hot off the press. Natural Product Reports, 31(12), pp. 1671-1675. (doi: 10.1039/C4NP90041C)
Grafton, M., Johnson, S. A., Farrugia, L. J. and Sutherland, A. (2014) Diastereoselective synthesis of highly substituted polycyclic scaffolds via a one-pot four-step tandem catalytic process. Tetrahedron Letters, 70(40), pp. 7133-7141. (doi: 10.1016/j.tet.2014.06.020)
Hill, R. A. and Sutherland, A. (2014) Hot off the press. Natural Product Reports, 31(10), pp. 1242-1246. (doi: 10.1039/C4NP90032D)
Hill, R. A. and Sutherland, A. (2014) Hot off the press. Natural Product Reports, 31(9), pp. 1083-1087. (doi: 10.1039/C4NP90023E)
Calder, E. D.D., McGonagle, F. I., Harkiss, A. H., McGonagle, G. A. and Sutherland, A. (2014) Preparation of amino-substituted indenes and 1,4-dihydronaphthalenes using a one-pot multireaction approach: total synthesis of oxybenzo[c]phenanthridine alkaloids. Journal of Organic Chemistry, 79(16), pp. 7633-7648. (doi: 10.1021/jo5014492) (PMID:25060853)
Hill, R. A. and Sutherland, A. (2014) Hot off the press. Natural Product Reports, 31(6), pp. 706-710. (doi: 10.1039/C4NP90015D)
Calder, E. D.D., Grafton, M. W. and Sutherland, A. (2014) One-pot multi-reaction processes: synthesis of natural products and drug-like scaffolds. Synlett, 25(8), pp. 1068-1080. (doi: 10.1055/s-0033-1340683)
Hill, R. A. and Sutherland, A. (2014) Hot off the press. Natural Product Reports, 31(4), pp. 414-418. (doi: 10.1039/C4NP90007C)
Hill, R. A. and Sutherland, A. (2014) Hot off the press. Natural Product Reports, 31(4), pp. 414-418. (doi: 10.1039/C3NP90044D)
Zaed, A. M., Grafton, M. W., Ahmad, S. and Sutherland, A. (2014) Asymmetric synthesis of cis-aminocyclopentenols, building blocks for medicinal chemistry. Journal of Organic Chemistry, 79(3), pp. 1511-1515. (doi: 10.1021/jo402712r)
Hill, R. A. and Sutherland, A. (2013) Hot off the press. Natural Product Reports, 30(12), pp. 1462-1466. (doi: 10.1039/C3NP90036C)
Hill, R. A. and Sutherland, A. (2013) Hot off the press. Natural Product Reports, 30(12), pp. 1462-1466. (doi: 10.1039/C3NP90029K)
Hill, R. A. and Sutherland, A. (2013) Hot off the press. Natural Product Reports, 30(12), pp. 1074-1078. (doi: 10.1039/C3NP90022C)
Cant, A.A., Champion, S. , Bhalla, R., Pimlott, S.L. and Sutherland, A. (2013) Nickel-mediated radioiodination of aryl and heteroaryl bromides: rapid synthesis of tracers for SPECT imaging. Angewandte Chemie (International Edition), 52(30), pp. 7829-7832. (doi: 10.1002/anie.201302800)
Calder, E.D.D., Zaed, A.M. and Sutherland, A. (2013) Preparation of anti-vicinal amino alcohols: asymmetric synthesis of D-erythro-Sphinganine, (+)-spisulosine and D-ribo-phytosphingosine. Journal of Organic Chemistry, 78(14), pp. 7223-7233. (doi: 10.1021/jo401211j)
Grafton, M. W., Farrugia, L. J. and Sutherland, A. (2013) Synthesis of amino substituted indanes and tetralins via consecutive multi-bond forming tandem processes. Journal of Organic Chemistry, 78(14), pp. 7199-7207. (doi: 10.1021/jo401182r)
Gilfillan, L., Blair, A., Morris, B. , Pratt, J., Schweiger, L., Pimlott, S. and Sutherland, A. (2013) Synthesis and biological evaluation of novel 2,3-dihydro-1H-1,5-benzodiazepin-2-ones; potential imaging agents of the metabotropic glutamate 2 receptor. MedChemComm, 4(7), pp. 1118-1123. (doi: 10.1039/c3md00110e)
Hill, R. A. and Sutherland, A. (2013) Hot off the press. Natural Product Reports, 30(12), pp. 760-764. (doi: 10.1039/C3NP90015K)
Hill, R. A. and Sutherland, A. (2013) Hot off the press. Natural Product Reports, 30(12), pp. 485-489. (doi: 10.1039/C3NP90007J)
Blair, A., Stevenson, L., Dewar, D. , Pimlott, S.L. and Sutherland, A. (2013) Structure–activity relationships of novel iodinated quinoline-2-carboxamides for targeting the translocator protein. MedChemComm, 4(11), pp. 1461-1466. (doi: 10.1039/c3md00249g)
Hill, R.A. and Sutherland, A. (2013) Hot off the press. Natural Product Reports, 30(2), pp. 213-217. (doi: 10.1039/C2NP90051C)
Blair, A., Stevenson, L. and Sutherland, A. (2012) Synthesis of the isoquinoline alkaloid, crispine C. Tetrahedron Letters, 53(32), pp. 4084-4086. (doi: 10.1016/j.tetlet.2012.05.113)
Ahmad, S., Swift, M., Farrugia, L., Senn, H.M. and Sutherland, A. (2012) Stereoselective synthesis of functionalised carbocyclic amides: construction of the syn-(4aS,10bS)-phenanthridone skeleton. Organic and Biomolecular Chemistry, 10(19), pp. 3937-3945. (doi: 10.1039/C2OB25334H)
Hill, R. and Sutherland, A. (2012) Hot off the press. Natural Product Reports, 29(2), p. 129. (doi: 10.1039/C1NP90052H)
Ahmad, S. and Sutherland, A. (2012) Stereoselective synthesis of hydroxylated 3-aminoazepanes using a multi-bond forming, three-step tandem process. Organic and Biomolecular Chemistry, 10(41), pp. 8251-8259. (doi: 10.1039/C2OB26544C)
Cant, A., Bhalla, R., Pimlott, S.L. and Sutherland, A. (2012) Nickel-catalysed aromatic Finkelstein reaction of aryl and heteroaryl bromides. Chemical Communications, 48(33), pp. 3993-3995. (doi: 10.1039/c2cc30956d)
Daly, M., Cant, A.A., Fowler, L.S., Simpson, G.L., Senn, H.M. and Sutherland, A. (2012) Switching the stereochemical outcome of 6-endo-trig cyclizations; Synthesis of 2,6-Cis-6-substituted 4-oxopipecolic acids. Journal of Organic Chemistry, 77(22), pp. 10001-10009. (doi: 10.1021/jo3022583)
Grafton, M.W., Farrugia, L.J., Senn, H.M. and Sutherland, A. (2012) Discovery of a multi-bond forming, four-step tandem process: construction of drug-like polycyclic scaffolds. Chemical Communications, 48, pp. 7994-7996. (doi: 10.1039/c2cc33649a)
Hill, R.A. and Sutherland, A. (2012) Hot off the press. Natural Product Reports, 29(4), pp. 435-439. (doi: 10.1039/C2NP90008D)
Hill, R.A. and Sutherland, A. (2012) Hot off the press. Natural Product Reports, 29(6), pp. 617-621. (doi: 10.1039/C2NP90016E)
Hill, R.A. and Sutherland, A. (2012) Hot off the press. Natural Product Reports, 29(8), p. 829. (doi: 10.1039/C2NP90024F)
Hill, R.A. and Sutherland, A. (2012) Hot off the press. Natural Product Reports, 29(10), pp. 1033-1037. (doi: 10.1039/C2NP90033E)
Hill, R.A. and Sutherland, A. (2012) Hot off the press. Natural Product Reports, 29(12), pp. 1377-1381. (doi: 10.1039/C2NP90041F)
Sutherland, A. and Cant, A. (2012) Asymmetric synthesis of pipecolic acid and derivatives. Synthesis, 44(13), pp. 1935-1950. (doi: 10.1055/s-0031-1289767)
Tavares, A.A.S., Jobson, N.K., Dewar, D. , Sutherland, A. , Pimlott, S.L. , Batis, J., Barret, O., Seibyl, J. and Tamagnan, G. (2012) Iodine-123 labeled reboxetine analogues for imaging of noradrenaline transporter in brain using single photon emission computed tomography. Synapse, 66(11), pp. 923-930. (doi: 10.1002/syn.21585)
Hill, R. and Sutherland, A. (2011) Hot off the press. Natural Product Reports, 28(12), p. 1879. (doi: 10.1039/C1NP90043A)
Zaed, A. and Sutherland, A. (2011) Total synthesis of clavaminol A, C and H. Organic and Biomolecular Chemistry, 9(23), pp. 8030-8037. (doi: 10.1039/C1OB06060K)
Daly, M., Gill, K., Sime, M., Simpson, G.L. and Sutherland, A. (2011) A new general approach for the stereocontrolled synthesis of functionalised γ- and δ-lactams. Organic and Biomolecular Chemistry, 9(19), p. 6761. (doi: 10.1039/C1OB05833A)
Fowler, L.S., Thomas, L.H., Ellis, D. and Sutherland, A. (2011) A one-pot reductive amination/6-endo-trig cyclisation for the stereoselective synthesis of 6-substituted-4-oxopipecolic acids. Chemical Communications, 47(23), pp. 6569-6571. (doi: 10.1039/c1cc11916h)
Tavares, A.A.S., Jobson, N.K., Dewar, D. , Sutherland, A. and Pimlott, S.L. (2011) Development of the radiosynthesis of high-specific-activity 123I-NKJ64. Nuclear Medicine and Biology, 38(4), pp. 493-500. (doi: 10.1016/j.nucmedbio.2010.11.011)
Ahmad, S., Thomas, L.H. and Sutherland, A. (2011) Stereoselective synthesis of polyhydroxylated aminocyclohexanes. Organic and Biomolecular Chemistry, 9, pp. 2801-2808. (doi: 10.1039/C0OB00619J)
Hill, R.A. and Sutherland, A. (2011) Hot off the press. Natural Product Reports, 28(6), pp. 1031-1034. (doi: 10.1039/C1NP90013G)
Hill, R.A. and Sutherland, A. (2011) Hot off the press. Natural Product Reports, 28(4), pp. 659-662. (doi: 10.1039/C1NP90009A)
Hill, R.A. and Sutherland, A. (2011) Hot off the press. Natural Product Reports, 28(8), pp. 1345-1349. (doi: 10.1039/C1NP90027G)
Hill, R.A. and Sutherland, A. (2011) Hot off the press. Natural Product Reports, 28(2), pp. 182-185. (doi: 10.1039/C0NP90038A)
Hill, R.A. and Sutherland, A. (2011) Hot off the press. Natural Product Reports, 28(10), pp. 1621-1625. (doi: 10.1039/C1NP90035H)
McGonagle, F.I., Brown, L., Cooke, A. and Sutherland, A. (2011) Microwave-promoted tandem reactions for the synthesis of bicyclic γ-lactams. Tetrahedron Letters, 52(18), pp. 2330-2332. (doi: 10.1016/j.tetlet.2011.02.089)
Pimlott, S.L. and Sutherland, A. (2011) Molecular tracers for the PET and SPECT imaging of disease. Chemical Society Reviews, 40(1), pp. 149-162. (doi: 10.1039/B922628C)
Tavares, A.A.S., Jobson, N.K., Dewar, D. , Sutherland, A. and Pimlott, S.L. (2011) 123I-NKJ64: A novel single photon emission computed tomography radiotracer for imaging the noradrenaline transporter in brain. Synapse, 65(7), pp. 658-667. (doi: 10.1002/syn.20895)
Tavares, A., Dewar, D. , Sutherland, A. and Pimlott, S. (2010) (R,S)-2-Iodo-reboxetine: development as a novel SPECT radiotracer for imaging the noradrenaline transporter in brain. NeuroImage, 52(S1), S115-S115. (doi: 10.1016/j.neuroimage.2010.04.094)
Drummond, L.J. and Sutherland, A. (2010) Asymmetric synthesis of allylic secondary alcohols: a new general approach for the preparation of α-amino acids. Tetrahedron, 66(29), pp. 5349-5356. (doi: 10.1016/j.tet.2010.05.066)
Hill, R.A. and Sutherland, A. (2010) Hot off the press. Natural Product Reports, 27(2), pp. 149-152. (doi: 10.1039/B926722K)
Hill, R.A. and Sutherland, A. (2010) Hot off the press. Natural Product Reports, 27(4), pp. 477-480. (doi: 10.1039/C003431M)
Hill, R.A. and Sutherland, A. (2010) Hot off the press. Natural Product Reports, 27(6), pp. 805-808. (doi: 10.1039/C005230M)
Hill, R.A. and Sutherland, A. (2010) Hot off the press. Natural Product Reports, 27(8), pp. 1110-1113. (doi: 10.1039/C005449F)
Hill, R.A. and Sutherland, A. (2010) Hot off the press. Natural Product Reports, 27(10), pp. 1381-1385. (doi: 10.1039/C0NP90017F)
Hill, R.A. and Sutherland, A. (2010) Hot off the press. Natural Product Reports, 27(12), pp. 1733-1736. (doi: 10.1039/C0NP90026E)
Kennedy, A.R., Kerr, W.J., Paterson, L.C. and Sutherland, A. (2010) A Tetrahydropentaleno[1,6a-a]naphthalen-4(2H)-one of Defined Relative Stereochemistry for Use Towards Agariblazeispirol C. Acta Crystallographica. Section D: Biological Crystallography, 66(9), 0473-0474. (doi: 10.1107/S0108270110031781)
McGonagle, F. I., Brown, L., Cooke, A. and Sutherland, A. (2010) A three-step tandem process for the synthesis of bicyclic gamma-lactams. Organic and Biomolecular Chemistry, 8(15), pp. 3418-3425. (doi: 10.1039/c004695g)
Stevenson, L., Tavares, A.A.S., Brunet, A., McGonagle, F.I., Dewar, D. , Pimlott, S.L. and Sutherland, A. (2010) New iodinated quinloine-2-varboxamides for SPECT imaging of the translocator protein. Bioorganic and Medicinal Chemistry Letters, 20(3), pp. 954-957. (doi: 10.1016/j.bmcl.2009.12.061)
Zaed, A.M. and Sutherland, A. (2010) Stereoselective synthesis of the bicyclic guanidine alkaloid (+)-monanchorin. Organic and Biomolecular Chemistry, 8(19), pp. 4394-4399. (doi: 10.1039/C0OB00219D)
Swift, M.D., Donaldson, A. and Sutherland, A. (2009) Tandem aza-Claisen rearrangement and ring closing metathesis reactions: the stereoselective synthesis of functionalised carbocyclic amides. Tetrahedron Letters, 50(26), pp. 3241-3244. (doi: 10.1016/j.tetlet.2009.02.032)
Fowler, L.S., Ellis, D. and Sutherland, A. (2009) Synthesis of fluorescent enone derived α-amino acids. Organic and Biomolecular Chemistry, 7(20), pp. 4309-4316. (doi: 10.1039/b912782h)
Hill, R.A. and Sutherland, A. (2009) Hot off the press. Natural Product Reports, 26(2), pp. 151-154. (doi: 10.1039/B822940F)
Hill, R.A. and Sutherland, A. (2009) Hot off the press. Natural Product Reports, 26(4), pp. 461-464. (doi: 10.1039/B903591P)
Hill, R.A. and Sutherland, A. (2009) Hot off the press. Natural Product Reports, 26(6), pp. 725-728. (doi: 10.1039/B908225P)
Hill, R.A. and Sutherland, A. (2009) Hot off the press. Natural Product Reports, 26(8), pp. 973-976. (doi: 10.1039/B912059A)
Hill, R.A. and Sutherland, A. (2009) Hot off the press. Natural Product Reports, 26(10), pp. 1229-1233. (doi: 10.1039/B917244K)
Hill, R.A. and Sutherland, A. (2009) Hot off the press. Natural Product Reports, 26(12), pp. 1517-1520. (doi: 10.1039/B921623P)
Jobson, N., Crawford, A., Dewar, D., Pimlott, S. and Sutherland, A. (2009) Design and synthesis of (2R,3S)-iodoreboxetine analogues for SPECT imaging of the noradrenaline transporter. Bioorganic and Medicinal Chemistry Letters, 19(17), pp. 4996-4998. (doi: 10.1016/j.bmcl.2009.07.064)
Zaed, A.M., Swift, M.D. and Sutherland, A. (2009) A stereoselective synthesis of (+)-physoperuvine using a tandem aza-Claisen rearrangement and ring closing metathesis reaction. Organic and Biomolecular Chemistry, 7(13), pp. 2678-2680. (doi: 10.1039/b907341h)
Hill, R.A. and Sutherland, A. (2008) Hot off the press. Natural Product Reports, 25(1), pp. 11-14. (doi: 10.1039/B719710C)
Hill, R.A. and Sutherland, A. (2008) Hot off the press. Natural Product Reports, 25(2), pp. 216-219. (doi: 10.1039/B803247P)
Hill, R.A. and Sutherland, A. (2008) Hot off the press. Natural Product Reports, 25(3), pp. 443-446. (doi: 10.1039/B806751C)
Hill, R.A. and Sutherland, A. (2008) Hot off the press. Natural Product Reports, 25(4), pp. 647-650. (doi: 10.1039/B810551K)
Hill, R.A. and Sutherland, A. (2008) Hot off the press. Natural Product Reports, 25(5), pp. 841-844. (doi: 10.1039/B814878N)
Hill, R.A. and Sutherland, A. (2008) Hot off the press. Natural Product Reports, 25(6), pp. 997-1000. (doi: 10.1039/b818366j)
Jobson, N., Crawford, A., Dewar, D., Pimlott, S. and Sutherland, A. (2008) New iodoreboxetine analogues for SPECT imaging of the noradrenaline transporter. Bioorganic and Medicinal Chemistry Letters, 18(18), pp. 4940-4943. (doi: 10.1016/j.bmcl.2008.08.041)
Jobson, N., Spike, R., Crawford, A., Dewar, D., Pimlott, S. and Sutherland, A. (2008) Stereoselective synthesis of (2S,3R)- and (2R,3S)-iodoreboxetine; potential SPECT imaging agents for the noradrenaline transporter. Organic and Biomolecular Chemistry, 6(13), pp. 2369-2376. (doi: 10.1039/b802819b)
Pimlott, S. L. , Stevenson, L., Wyper, D. J. and Sutherland, A. (2008) Rapid and efficient radiosynthesis of [I-123]I-PK11195, a single photon emission computed tomography tracer for peripheral benzodiazepine receptors. Nuclear Medicine and Biology, 35(5), pp. 537-542. (doi: 10.1016/j.nucmedbio.2008.02.013)
Swift, M. D. and Sutherland, A. (2008) Studies on the aza-Claisen rearrangement of 4,5-dihydroxylated allylic trichloroacetimidates: the stereoselective synthesis of (2R,3S)- and (2S,3S)-2-amino-3,4-dihydroxybutyric acids. Tetrahedron, 64(40), pp. 9521-9527. (doi: 10.1016/j.tet.2008.07.062)
Stevenson, L., Pimlott, S. L. and Sutherland, A. (2007) A novel approach for the synthesis of the peripheral benzodiazepine receptor ligand, PK11195. Tetrahedron Letters, 48(40), pp. 7137-7139. (doi: 10.1016/j.tetlet.2007.07.203)
Jamieson, A. G. and Sutherland, A. (2007) Ether-directed palladium(II)-catalysed aza-Claisen rearrangements: studies on the origin of the directing effect. Tetrahedron, 63, pp. 2123-2131. (doi: 10.1016/j.tet.2006.12.067)
Bischoff, R., Hamilton, D., Jobson, N. and Sutherland, A. (2007) New approaches for the synthesis of isotopically labelled guanidine-derived amino acids and noradrenaline reuptake inhibitors. Journal of Labelled Compounds and Radiopharmaceuticals, 50, pp. 323-326. (doi: 10.1002/jlcr.1242)
Fanning, K. N. and Sutherland, A. (2007) A facile synthesis of (S)-gizzerosine, a potent agonist of the histamine H-2-receptor. Tetrahedron Letters, 48(48), pp. 8479-8481. (doi: 10.1016/j.tetlet.2007.09.165)
Jamieson, A. G. and Sutherland, A. (2007) Ether-directed, stereoselective aza-Claisen rearrangements: Synthesis of the piperidine alkaloid, alpha-conhydrine. Organic Letters, 9, pp. 1609-1611. (doi: 10.1021/ol070424z) (PMID:17371038)
Pillai, B., Cherney, M., Diaper, C., Sutherland, A. , Blanchard, J., Vederas, J. and James, M. (2007) Dynamics of catalysis revealed from the crystal structures of mutants of diaminopimelate epimerase. Biochemical and Biophysical Research Communications, 363, pp. 547-553. (doi: 10.1016/j.bbrc.2007.09.012)
Swift, M. D. and Sutherland, A. (2007) A tandem aza-Claisen rearrangement and ring closing metathesis reaction for the synthesis of cyclic allylic trichloroacetamides. Organic Letters, 9(25), pp. 5239-5242. (doi: 10.1021/ol702299c Univ Glasgow, Dept Chem, Glasgow G12 8QQ, Lanark, Scotland.)
Swift, M. and Sutherland, A. (2007) A stereoselective synthesis of (2R,3S)-2-amino-3,4-dihydroxybutyric acid using an ether directed aza-Claisen rearrangement. Tetrahedron Letters, 48, pp. 3771-3773. (doi: 10.1016/j.tetlet.2007.03.161)
Wilson, J., Henderson, G., Black, F., Sutherland, A., Ludwig, R., Vousden, K. and Robins, D. (2007) Synthesis of 5-deazaflavin derivatives and their activation of p53 in cells. Bioorganic and Medicinal Chemistry Letters, 15, pp. 77-86. (doi: 10.1016/j.bmc.2006.10.011)
Wilson, J., Giordani, F., Farrugia, L., Barrett, M., Robinsa, D. and Sutherland, A. (2007) Synthesis, characterisation and anti-protozoal activity of carbamate-derived polyazamacrocycles. Organic and Biomolecular Chemistry, 5, pp. 3651-3656. (doi: 10.1039/b710487a)
Fanning, K. N., Jamieson, A. G. and Sutherland, A. (2006) Palladium(II)-catalysed rearrangement reactions. Current Organic Chemistry, 10(9), pp. 1007-1020. (doi: 10.2174/138527206777435490)
Jamieson, A. G. and Sutherland, A. (2006) Scope and limitations of ether-directed, metal-catalysed aza-Claisen rearrangements; improved stereoselectivity using non-coordinating solvents. Organic and Biomolecular Chemistry, 4, pp. 2932-2937. (doi: 10.1039/b607014k) (PMID:16855742)
Pillai, B., Cherney, M., Diaper, C., Sutherland, A. , Blanchard, J., Vederas, J. and James, M. (2006) Structural insights into stereochemical inversion by diaminopimelate epimerase: An antibacterial drug target. Proceedings of the National Academy of Sciences of the United States of America, 103(23), pp. 8668-8673. (doi: 10.1073/pnas.0602537103)
Swift, M. and Sutherland, A. (2006) Stereocontrol of palladium(II)-catalysed aza-Claisen rearrangements using a combination of 1,3-allylic strain and a solvent mediated directing effect. Organic and Biomolecular Chemistry, 4, pp. 3889-3891. (doi: 10.1039/b613271e)
Bischoff, R., McDonald, N. and Sutherland, A. (2005) A highly efficient, asymmetric synthesis of blastidic acid: the beta-amino acid component of the antibiotic, (+)-blasticidin S. Tetrahedron Letters, 46, pp. 7147-7149. (doi: 10.1016/j.tetlet.2005.08.096)
Diaper, C., Sutherland, A. , Pillai, B., James, M., Semchuk, P., Blanchard, J. and Vederas, J. (2005) The stereoselective synthesis of aziridine analogues of diaminopimelic acid (DAP) and their interaction with dap epimerase. Organic and Biomolecular Chemistry, 3, pp. 4402-4411. (doi: 10.1039/b513409a)
Fanning, K. N., Jamieson, A. G. and Sutherland, A. (2005) Stereoselective beta-hydroxy-alpha-amino acid synthesis via an ether-directed, palladium-catalysed aza-Claisen rearrangement. Organic and Biomolecular Chemistry, 3, pp. 3749-3756. (doi: 10.1039/b510808j) (PMID:16211111)
Jamieson, A. G. and Sutherland, A. (2005) A highly stereoselective ether directed palladium catalysed aza-Claisen rearrangement. Organic and Biomolecular Chemistry, 3, pp. 735-736. (PMID:15731857)
Hamilton, D. and Sutherland, A. (2004) A flexible approach for the synthesis of selectively labelled L-arginine. Tetrahedron Letters, 45, pp. 5739-5741. (doi: 10.1016/j.tetlet.2004.05.096)
Jamieson, A. G. , Sutherland, A. and Willis, C. L. (2004) The first enantioselective synthesis of the amino acid, (2S,3S,4R)-gamma-hydroxyisoleucine using a palladium(II) catalysed 3,3-sigmatropic rearrangement. Organic and Biomolecular Chemistry, 2, pp. 808-809. (doi: 10.1039/b401076k)
Book Sections
Welch, A., Tavares, A. A. S., Pimlott, S. and Sutherland, A. (2021) PET and SPECT in drug development. In: Abraham, Donald J. (ed.) Burger's Medicinal Chemistry, Drug Discovery and Development. Wiley. ISBN 9780470278154 (doi: 10.1002/0471266949.bmc254.pub2)
Fowler, L.S., Sutherland, A. , Procter, J. and Molander, G.A. (2011) Product class 6: acyclic and semicyclic o/o acetals. In: Ishihara, K., Krause, N. and Procter, D. (eds.) Science of Synthesis Knowledge Updates. Thieme, p. 121. ISBN 9783131541611
Reid., C.M. and Sutherland, A. (2009) Synthesis of isotopically labeled α-amino acids. In: Hughes, A.B. (ed.) Amino Acids, Peptides and Proteins in Organic Chemistry. Vol. 1. Origins and Synthesis of Amino Acids. Wiley-VCH: Weinham, Germany. ISBN 9783527320967
Conference or Workshop Item
Cant, A. A., Racys, D. T., Pimlott, S. L. and Sutherland, A. (2016) New reactions for the synthesis of aryl iodides and the generation of single-photon emission computed tomography imaging agents. 24th international isotope society (UK group) symposium, Cambridge, UK, 06 Nov 2015. p. 182. (doi: 10.1002/jlcr.3377)
Blair, A., Pimlott, S. , Schwieger, L. and Sutherland, A. (2013) New PET and SPECT imaging agents for the translocator protein (18 kDa). 245th National Spring Meeting of the American-Chemical-Society (ACS), New Orleans, Louisiana, USA, 07-11 Apr 2013.
Tavares, A. A. S., Jobson, N. K., Dewar, D. , Sutherland, A. , Pimlott, S. L. , Batis, J., Barret, O., Baldwin, R., Seibyl, J. and Tamagnan, G. (2012) Radioiodinated reboxetine analogues for imaging of the norepinephrine transporters in brain using single photon emission computed tomography. 9th International Symposium on Functional Neuroreceptor Mapping of the Living Brain (NRM), Baltimore, Maryland, USA, 09-11 Aug 2012. S103-S104. (doi: 10.1038/jcbfm.2012.79)
Teaching
Teaching
- Level-2 Isomerism and Stereochemistry
- Level-4 Pericyclic Reactions
Additional information
Awards
BSc (Edinburgh) PhD (Bristol) FRSC CChem
Selected Recent Talks
- Regioselective Transition Metal Catalysed Aryl C-X, C-N and C-O Bond Formation, University of Strathclyde, February 2020.
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New PET Tracers for the Imaging of Inflammation, French Medicinal Chemistry Society, Normandy (University of Caen), January 2020.
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Regioselective Transition Metal Catalysed Aryl C-X, C-N and C-O Bond Formation, Sygnature Discovery, Nottingham, December 2019.
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New Molecular Tracers for PET Imaging of the Translocator Protein (TSPO), PET is Wonderful Annual Meeting, University of Edinburgh, October 2018.
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Charge-Transfer Based Pyridyl-Derived Amino Acids: Highly Fluorescent Probes for In Vivo Cell Imaging, 101st Canadian Society for Chemistry National Meeting, Edmonton, Canada, May 2018.
- Regioselective Iron Catalysed Functionalisation of Arenes, 23rd Royal Society of Chemistry, Grasmere Synthesis Meeting, Lake District, May 2017.
External Appointments & Positions
- EPSRC College and Panel Member
- Member of the SINAPSE Molecular Imaging Committee
