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email:
Alexander.Harkiss@glasgow.ac.uk
School of Chemistry, Joseph Black Building, University of Glasgow, Glasgow, G12 8QQ
Research Associate in the Cooke Research Group
Riley, L. M. , Marshall, O., Harkiss, A. H., Senn, H. M. and Sutherland, A. (2024) Synthesis of β-pyridyl α-amino acids: conformationally sensitive charge transfer-based fluorophores. Organic Letters, 26(25), pp. 5391-5395. (doi: 10.1021/acs.orglett.4c01951) (PMID:38865167) (PMCID:PMC11217948)
Songsri, S., Harkiss, A. H. and Sutherland, A. (2023) Synthesis and photophysical properties of charge-transfer based pyrimidine-derived ∝-amino acids. Journal of Organic Chemistry, 88(18), pp. 13214-13224. (doi: 10.1021/acs.joc.3c01437) (PMID:37621156) (PMCID:PMC10507667)
Uno, S., Harkiss, A. H., Chowdhury, R., Caldwell, S. T. , Prime, T. A., James, A. M., Gallagher, B., Prudent, J., Hartley, R. C. and Murphy, M. P. (2023) Incorporating a polyethyleneglycol linker to enhance the hydrophilicity of mitochondria‐targeted triphenylphosphonium constructs. ChemBioChem, 24(11), e202200774. (doi: 10.1002/cbic.202200774) (PMID:36917207)
Cariello, M. , Pant, N., Harkiss, A. H., Tracey, F. M., Cameron, J. , Skabara, P. J. , Holliman, P. J., Docampo, P. and Cooke, G. (2022) Synthesis of SOT-OH and its application as a building block for the synthesis of new dimeric and trimeric Spiro-OMeTAD materials. Molecular Systems Design and Engineering, 7(8), pp. 899-905. (doi: 10.1039/D2ME00038E)
Bell, J. D., Harkiss, A. H., Nobis, D., Malcolm, E., Knuhtsen, A., Wellaway, C. R., Jamieson, A. G. , Magennis, S. W. and Sutherland, A. (2020) Conformationally rigid pyrazoloquinazoline α-amino acids: one- and two-photon induced fluorescence. Chemical Communications, 56(12), pp. 1887-1890. (doi: 10.1039/C9CC09064A) (PMID:31956866)
Bell, J. D., Morgan, T. E.F., Buijs, N., Harkiss, A. H., Wellaway, C. R. and Sutherland, A. (2019) Synthesis and photophysical properties of benzotriazole-derived unnatural α -amino acids. Journal of Organic Chemistry, 84(16), pp. 10436-10448. (doi: 10.1021/acs.joc.9b01685) (PMID:31340638)
Harkiss, A. H., Bell, J. D., Knuhtsen, A., Jamieson, A. G. and Sutherland, A. (2019) Synthesis and fluorescent properties of β-pyridyl α-amino acids. Journal of Organic Chemistry, 84(5), pp. 2879-2890. (doi: 10.1021/acs.joc.9b00036) (PMID:30726078)
Bell, J. D., Harkiss, A. H., Wellaway, C. R. and Sutherland, A. (2018) Stereoselective synthesis of 2,6-trans-4-oxopiperidines using an acid-mediated 6-endo-trig cyclisation. Organic and Biomolecular Chemistry, 16(35), pp. 6410-6422. (doi: 10.1039/C8OB01363B) (PMID:30011344)
Harkiss, A. H. and Sutherland, A. (2018) Access to 2,6-disubstituted 4-oxopiperidines using a 6-endo-trig cyclization: stereoselective synthesis of spruce alkaloid and (+)-241D. Journal of Organic Chemistry, 83(1), pp. 535-542. (doi: 10.1021/acs.joc.7b02799) (PMID:29218988)
Sharif, S. A.I., Calder, E. D.D., Harkiss, A., Maduro, M. and Sutherland, A. (2016) Synthesis of allylic amide functionalized 2H-chromenes and coumarins using a one-pot overman rearrangement and gold(I)-catalyzed hydroarylation. Journal of Organic Chemistry, 81(20), pp. 9810-9819. (doi: 10.1021/acs.joc.6b01881) (PMID:27680202)
Harkiss, A. and Sutherland, A. (2016) Recent advances in the synthesis and application of fluorescent α-amino acids. Organic and Biomolecular Chemistry, 14(38), pp. 8911-8921. (doi: 10.1039/C6OB01715K) (PMID:27714204)
Gilfillan, L., Artschwager, R., Harkiss, A. H., Liskamp, R. M.J. and Sutherland, A. (2015) Synthesis of pyrazole containing α-amino acids via a highly regioselective condensation/aza-Michael reaction of β-aryl α,β-unsaturated ketones. Organic and Biomolecular Chemistry, 13(15), pp. 4514-4523. (doi: 10.1039/C5OB00364D) (PMID:25774874)
Calder, E. D.D., McGonagle, F. I., Harkiss, A. H., McGonagle, G. A. and Sutherland, A. (2014) Preparation of amino-substituted indenes and 1,4-dihydronaphthalenes using a one-pot multireaction approach: total synthesis of oxybenzo[c]phenanthridine alkaloids. Journal of Organic Chemistry, 79(16), pp. 7633-7648. (doi: 10.1021/jo5014492) (PMID:25060853)
Riley, L. M. , Marshall, O., Harkiss, A. H., Senn, H. M. and Sutherland, A. (2024) Synthesis of β-pyridyl α-amino acids: conformationally sensitive charge transfer-based fluorophores. Organic Letters, 26(25), pp. 5391-5395. (doi: 10.1021/acs.orglett.4c01951) (PMID:38865167) (PMCID:PMC11217948)
Songsri, S., Harkiss, A. H. and Sutherland, A. (2023) Synthesis and photophysical properties of charge-transfer based pyrimidine-derived ∝-amino acids. Journal of Organic Chemistry, 88(18), pp. 13214-13224. (doi: 10.1021/acs.joc.3c01437) (PMID:37621156) (PMCID:PMC10507667)
Uno, S., Harkiss, A. H., Chowdhury, R., Caldwell, S. T. , Prime, T. A., James, A. M., Gallagher, B., Prudent, J., Hartley, R. C. and Murphy, M. P. (2023) Incorporating a polyethyleneglycol linker to enhance the hydrophilicity of mitochondria‐targeted triphenylphosphonium constructs. ChemBioChem, 24(11), e202200774. (doi: 10.1002/cbic.202200774) (PMID:36917207)
Cariello, M. , Pant, N., Harkiss, A. H., Tracey, F. M., Cameron, J. , Skabara, P. J. , Holliman, P. J., Docampo, P. and Cooke, G. (2022) Synthesis of SOT-OH and its application as a building block for the synthesis of new dimeric and trimeric Spiro-OMeTAD materials. Molecular Systems Design and Engineering, 7(8), pp. 899-905. (doi: 10.1039/D2ME00038E)
Bell, J. D., Harkiss, A. H., Nobis, D., Malcolm, E., Knuhtsen, A., Wellaway, C. R., Jamieson, A. G. , Magennis, S. W. and Sutherland, A. (2020) Conformationally rigid pyrazoloquinazoline α-amino acids: one- and two-photon induced fluorescence. Chemical Communications, 56(12), pp. 1887-1890. (doi: 10.1039/C9CC09064A) (PMID:31956866)
Bell, J. D., Morgan, T. E.F., Buijs, N., Harkiss, A. H., Wellaway, C. R. and Sutherland, A. (2019) Synthesis and photophysical properties of benzotriazole-derived unnatural α -amino acids. Journal of Organic Chemistry, 84(16), pp. 10436-10448. (doi: 10.1021/acs.joc.9b01685) (PMID:31340638)
Harkiss, A. H., Bell, J. D., Knuhtsen, A., Jamieson, A. G. and Sutherland, A. (2019) Synthesis and fluorescent properties of β-pyridyl α-amino acids. Journal of Organic Chemistry, 84(5), pp. 2879-2890. (doi: 10.1021/acs.joc.9b00036) (PMID:30726078)
Bell, J. D., Harkiss, A. H., Wellaway, C. R. and Sutherland, A. (2018) Stereoselective synthesis of 2,6-trans-4-oxopiperidines using an acid-mediated 6-endo-trig cyclisation. Organic and Biomolecular Chemistry, 16(35), pp. 6410-6422. (doi: 10.1039/C8OB01363B) (PMID:30011344)
Harkiss, A. H. and Sutherland, A. (2018) Access to 2,6-disubstituted 4-oxopiperidines using a 6-endo-trig cyclization: stereoselective synthesis of spruce alkaloid and (+)-241D. Journal of Organic Chemistry, 83(1), pp. 535-542. (doi: 10.1021/acs.joc.7b02799) (PMID:29218988)
Sharif, S. A.I., Calder, E. D.D., Harkiss, A., Maduro, M. and Sutherland, A. (2016) Synthesis of allylic amide functionalized 2H-chromenes and coumarins using a one-pot overman rearrangement and gold(I)-catalyzed hydroarylation. Journal of Organic Chemistry, 81(20), pp. 9810-9819. (doi: 10.1021/acs.joc.6b01881) (PMID:27680202)
Harkiss, A. and Sutherland, A. (2016) Recent advances in the synthesis and application of fluorescent α-amino acids. Organic and Biomolecular Chemistry, 14(38), pp. 8911-8921. (doi: 10.1039/C6OB01715K) (PMID:27714204)
Gilfillan, L., Artschwager, R., Harkiss, A. H., Liskamp, R. M.J. and Sutherland, A. (2015) Synthesis of pyrazole containing α-amino acids via a highly regioselective condensation/aza-Michael reaction of β-aryl α,β-unsaturated ketones. Organic and Biomolecular Chemistry, 13(15), pp. 4514-4523. (doi: 10.1039/C5OB00364D) (PMID:25774874)
Calder, E. D.D., McGonagle, F. I., Harkiss, A. H., McGonagle, G. A. and Sutherland, A. (2014) Preparation of amino-substituted indenes and 1,4-dihydronaphthalenes using a one-pot multireaction approach: total synthesis of oxybenzo[c]phenanthridine alkaloids. Journal of Organic Chemistry, 79(16), pp. 7633-7648. (doi: 10.1021/jo5014492) (PMID:25060853)
Uno, S., Harkiss, A., Chowdhury, R., Caldwell, S. , Prime, T. A., James, A. M., Gallagher, B., Prudent, J., Hartley, R. and Murphy, M. (2023) Incorporating a Polyethyleneglycol Linker to Enhance the Hydrophilicity of Mitochondria-Targeted Triphenylphosphonium Constructs. [Data Collection]
