2024

Rios, F. J. et al. (2024) Mechanisms of vascular inflammation and potential therapeutic targets: a position paper from the ESH Working Group on Small Arteries. Hypertension, 81(6), pp. 1218-1232. (doi: 10.1161/hypertensionaha.123.22483) (PMID:38511317)

Guzik, T. J., Nosalski, R., Maffia, P. and Drummond, G. R. (2024) Immune and inflammatory mechanisms in hypertension. Nature Reviews Cardiology, (doi: 10.1038/s41569-023-00964-1) (PMID:38172242) (Early Online Publication)

2022

Szczepaniak, P. et al. (2022) Breast cancer chemotherapy induces vascular dysfunction and hypertension through NOX4 dependent mechanism. Journal of Clinical Investigation, 132(13), e149117. (doi: 10.1172/JCI149117) (PMID:35617030) (PMCID:PMC9246378)

Mohanta, S. K. et al. (2022) Neuroimmune cardiovascular interfaces control atherosclerosis. Nature, 605(7908), pp. 152-159. (doi: 10.1038/s41586-022-04673-6) (PMID:35477759)

2021

Murray, E. C. , Nosalski, R., MacRitchie, N., Tomaszewski, M., Maffia, P. , Harrison, D. G. and Guzik, T. J. (2021) Therapeutic targeting of inflammation in hypertension: from novel mechanisms to translational perspective. Cardiovascular Research, 117(13), pp. 2589-2609. (doi: 10.1093/cvr/cvab330) (PMID:34698811)

Konior-Rozlachowska, A., Siedlinski, M., Szczepaniak, P., Nosalski, R., Murray, E. and Mikolajczyk, T.P. (2021) Systemic and vascular inflammation in experimental allergic asthma. Journal of Physiology and Pharmacology, 72(2), (doi: 10.26402/jpp.2021.2.03) (PMID:34374654)

2020

Nosalski, R., Mikolajczyk, T., Siedlinski, M., Saju, B., Koziol, J., Maffia, P. and Guzik, T.J. (2020) Nox1/4 inhibition exacerbates age dependent perivascular inflammation and fibrosis in a model of spontaneous hypertension. Pharmacological Research, 161, 105235. (doi: 10.1016/j.phrs.2020.105235) (PMID:33131726) (PMCID:PMC8316606)

Guzik, T. J. et al. (2020) COVID-19 and the cardiovascular system: implications for risk assessment, diagnosis, and treatment options. Cardiovascular Research, 116(10), pp. 1666-1687. (doi: 10.1093/cvr/cvaa106) (PMID:32352535) (PMCID:PMC7197627)

Nosalski, R. et al. (2020) T cell-derived miRNA-214 mediates perivascular fibrosis in hypertension. Circulation Research, 126, pp. 988-1003. (doi: 10.1161/CIRCRESAHA.119.315428) (PMID:32065054) (PMCID:PMC7147427)

Rios, F. J. et al. (2020) Chanzyme TRPM7 protects against cardiovascular inflammation and fibrosis. Cardiovascular Research, 116(3), pp. 721-735. (doi: 10.1093/cvr/cvz164) (PMID:31250885) (PMCID:PMC7252442)

2019

Czesnikiewicz-Guzik, M. et al. (2019) Causal association between periodontitis and hypertension: evidence from Mendelian randomization and a randomized controlled trial of non-surgical periodontal therapy. European Heart Journal, 40(42), pp. 3459-3470. (doi: 10.1093/eurheartj/ehz646) (PMID:31504461) (PMCID:PMC6837161)

Czesnikiewicz-Guzik, M. , Nosalski, R., Mikolajczyk, T. P., Vidler, F., Dohnal, T., Dembowska, E., Graham, D. , Harrison, D. G. and Guzik, T. J. (2019) Th1 type immune responses to Porphyromonas gingivalis antigens exacerbate angiotensin II dependent hypertension and vascular dysfunction. British Journal of Pharmacology, 176(12), pp. 1922-1931. (doi: 10.1111/bph.14536) (PMID:30414380) (PMCID:PMC6534780)

Mikolajczyk, T. P. et al. (2019) 1,2,3,4,6 penta-O -galloyl-β-D-glucose modulates perivascular inflammation and prevents vascular dysfunction in angiotensin II-induced hypertension. British Journal of Pharmacology, 176(12), pp. 1951-1965. (doi: 10.1111/bph.14583) (PMID:30658013) (PMCID:PMC6534792)

2018

Maffia, P. , Nosalski, R. and Guzik, T. J. (2018) Monocytes M(MP)aking way for T cell vascular infiltration. Circulation Research, 123(6), pp. 638-640. (doi: 10.1161/CIRCRESAHA.118.313668) (PMID:30355241)

2017

Skiba, D.S. et al. (2017) Anti‐atherosclerotic effect of the angiotensin 1–7 mimetic AVE0991 is mediated by inhibition of perivascular and plaque inflammation in early atherosclerosis. British Journal of Pharmacology, 174(22), pp. 4055-4069. (doi: 10.1111/bph.13685) (PMID:27935022) (PMCID:PMC5659999)

Nosalski, R. and Guzik, T. J. (2017) Perivascular adipose tissue inflammation in vascular disease. British Journal of Pharmacology, 174(20), pp. 3496-3513. (doi: 10.1111/bph.13705) (PMID:28063251)

Nosalski, R., McGinnigle, E., Siedlinski, M. and Guzik, T. J. (2017) Novel immune mechanisms in hypertension and cardiovascular risk. Current Cardiovascular Risk Reports, 11(4), 12. (doi: 10.1007/s12170-017-0537-6)

Siedlinski, M. et al. (2017) Vascular transcriptome profiling identifies Sphingosine kinase 1 as a modulator of angiotensin II-induced vascular dysfunction. Scientific Reports, 7, 44131. (doi: 10.1038/srep44131) (PMID:28276483) (PMCID:PMC5343497)

2016

Small, H. Y., Nosalski, R., Morgan, H., Beattie, E., Guzik, T., Graham, D. and Delles, C. (2016) The role of tumor necrosis factor-α and natural killer cells in uterine artery function and pregnancy outcome in the stroke prone spontaneously hypertensive rat. Hypertension, 68(5), pp. 1298-1307. (doi: 10.1161/HYPERTENSIONAHA.116.07933) (PMID:27733586) (PMCID:PMC5058643)

Urbanski, K., Filip, G., Filip, M., Ludew, D., Szczepaniak, P., Nosalski, R.,, Sagan, A., Mikolajczyk, T., Kapelak, B. and Guzik, T.J. (2016) [OP.2D.04] Perivascular T regulatory cells and endothelial dysfunction in human atherosclerosis. Journal of Hypertension, 34(S2), e24-e25. (doi: 10.1097/01.hjh.0000491394.17973.0a) (PMID:27508639)

Mikolajczyk, T.P. et al. (2016) Role of chemokine RANTES in the regulation of perivascular inflammation, T-cell accumulation, and vascular dysfunction in hypertension. FASEB Journal, 30(5), pp. 1987-1999. (doi: 10.1096/fj.201500088R) (PMID:26873938) (PMCID:PMC4836375)

Articles

Rios, F. J. et al. (2024) Mechanisms of vascular inflammation and potential therapeutic targets: a position paper from the ESH Working Group on Small Arteries. Hypertension, 81(6), pp. 1218-1232. (doi: 10.1161/hypertensionaha.123.22483) (PMID:38511317)

Guzik, T. J., Nosalski, R., Maffia, P. and Drummond, G. R. (2024) Immune and inflammatory mechanisms in hypertension. Nature Reviews Cardiology, (doi: 10.1038/s41569-023-00964-1) (PMID:38172242) (Early Online Publication)

Szczepaniak, P. et al. (2022) Breast cancer chemotherapy induces vascular dysfunction and hypertension through NOX4 dependent mechanism. Journal of Clinical Investigation, 132(13), e149117. (doi: 10.1172/JCI149117) (PMID:35617030) (PMCID:PMC9246378)

Mohanta, S. K. et al. (2022) Neuroimmune cardiovascular interfaces control atherosclerosis. Nature, 605(7908), pp. 152-159. (doi: 10.1038/s41586-022-04673-6) (PMID:35477759)

Murray, E. C. , Nosalski, R., MacRitchie, N., Tomaszewski, M., Maffia, P. , Harrison, D. G. and Guzik, T. J. (2021) Therapeutic targeting of inflammation in hypertension: from novel mechanisms to translational perspective. Cardiovascular Research, 117(13), pp. 2589-2609. (doi: 10.1093/cvr/cvab330) (PMID:34698811)

Konior-Rozlachowska, A., Siedlinski, M., Szczepaniak, P., Nosalski, R., Murray, E. and Mikolajczyk, T.P. (2021) Systemic and vascular inflammation in experimental allergic asthma. Journal of Physiology and Pharmacology, 72(2), (doi: 10.26402/jpp.2021.2.03) (PMID:34374654)

Nosalski, R., Mikolajczyk, T., Siedlinski, M., Saju, B., Koziol, J., Maffia, P. and Guzik, T.J. (2020) Nox1/4 inhibition exacerbates age dependent perivascular inflammation and fibrosis in a model of spontaneous hypertension. Pharmacological Research, 161, 105235. (doi: 10.1016/j.phrs.2020.105235) (PMID:33131726) (PMCID:PMC8316606)

Guzik, T. J. et al. (2020) COVID-19 and the cardiovascular system: implications for risk assessment, diagnosis, and treatment options. Cardiovascular Research, 116(10), pp. 1666-1687. (doi: 10.1093/cvr/cvaa106) (PMID:32352535) (PMCID:PMC7197627)

Nosalski, R. et al. (2020) T cell-derived miRNA-214 mediates perivascular fibrosis in hypertension. Circulation Research, 126, pp. 988-1003. (doi: 10.1161/CIRCRESAHA.119.315428) (PMID:32065054) (PMCID:PMC7147427)

Rios, F. J. et al. (2020) Chanzyme TRPM7 protects against cardiovascular inflammation and fibrosis. Cardiovascular Research, 116(3), pp. 721-735. (doi: 10.1093/cvr/cvz164) (PMID:31250885) (PMCID:PMC7252442)

Czesnikiewicz-Guzik, M. et al. (2019) Causal association between periodontitis and hypertension: evidence from Mendelian randomization and a randomized controlled trial of non-surgical periodontal therapy. European Heart Journal, 40(42), pp. 3459-3470. (doi: 10.1093/eurheartj/ehz646) (PMID:31504461) (PMCID:PMC6837161)

Czesnikiewicz-Guzik, M. , Nosalski, R., Mikolajczyk, T. P., Vidler, F., Dohnal, T., Dembowska, E., Graham, D. , Harrison, D. G. and Guzik, T. J. (2019) Th1 type immune responses to Porphyromonas gingivalis antigens exacerbate angiotensin II dependent hypertension and vascular dysfunction. British Journal of Pharmacology, 176(12), pp. 1922-1931. (doi: 10.1111/bph.14536) (PMID:30414380) (PMCID:PMC6534780)

Mikolajczyk, T. P. et al. (2019) 1,2,3,4,6 penta-O -galloyl-β-D-glucose modulates perivascular inflammation and prevents vascular dysfunction in angiotensin II-induced hypertension. British Journal of Pharmacology, 176(12), pp. 1951-1965. (doi: 10.1111/bph.14583) (PMID:30658013) (PMCID:PMC6534792)

Maffia, P. , Nosalski, R. and Guzik, T. J. (2018) Monocytes M(MP)aking way for T cell vascular infiltration. Circulation Research, 123(6), pp. 638-640. (doi: 10.1161/CIRCRESAHA.118.313668) (PMID:30355241)

Skiba, D.S. et al. (2017) Anti‐atherosclerotic effect of the angiotensin 1–7 mimetic AVE0991 is mediated by inhibition of perivascular and plaque inflammation in early atherosclerosis. British Journal of Pharmacology, 174(22), pp. 4055-4069. (doi: 10.1111/bph.13685) (PMID:27935022) (PMCID:PMC5659999)

Nosalski, R. and Guzik, T. J. (2017) Perivascular adipose tissue inflammation in vascular disease. British Journal of Pharmacology, 174(20), pp. 3496-3513. (doi: 10.1111/bph.13705) (PMID:28063251)

Nosalski, R., McGinnigle, E., Siedlinski, M. and Guzik, T. J. (2017) Novel immune mechanisms in hypertension and cardiovascular risk. Current Cardiovascular Risk Reports, 11(4), 12. (doi: 10.1007/s12170-017-0537-6)

Siedlinski, M. et al. (2017) Vascular transcriptome profiling identifies Sphingosine kinase 1 as a modulator of angiotensin II-induced vascular dysfunction. Scientific Reports, 7, 44131. (doi: 10.1038/srep44131) (PMID:28276483) (PMCID:PMC5343497)

Small, H. Y., Nosalski, R., Morgan, H., Beattie, E., Guzik, T., Graham, D. and Delles, C. (2016) The role of tumor necrosis factor-α and natural killer cells in uterine artery function and pregnancy outcome in the stroke prone spontaneously hypertensive rat. Hypertension, 68(5), pp. 1298-1307. (doi: 10.1161/HYPERTENSIONAHA.116.07933) (PMID:27733586) (PMCID:PMC5058643)

Urbanski, K., Filip, G., Filip, M., Ludew, D., Szczepaniak, P., Nosalski, R.,, Sagan, A., Mikolajczyk, T., Kapelak, B. and Guzik, T.J. (2016) [OP.2D.04] Perivascular T regulatory cells and endothelial dysfunction in human atherosclerosis. Journal of Hypertension, 34(S2), e24-e25. (doi: 10.1097/01.hjh.0000491394.17973.0a) (PMID:27508639)

Mikolajczyk, T.P. et al. (2016) Role of chemokine RANTES in the regulation of perivascular inflammation, T-cell accumulation, and vascular dysfunction in hypertension. FASEB Journal, 30(5), pp. 1987-1999. (doi: 10.1096/fj.201500088R) (PMID:26873938) (PMCID:PMC4836375)