Dr Martin McBride

Senior Lecturer - Systems Medicine Coordinator (Cardiovascular & Metabolic Health)

telephone: 01413302911
email: Martin.McBride@glasgow.ac.uk

RC436 Level C4, Institute of C&MS, Bhf Gcrc, Glasgow G12 8TA

Research interests

Research Theme: Cardiovascular Data Science

I currently hold a lectureship that is externally funded by the British Heart Foundation. I completed my undergraduate and postgraduate training in Genetics at the University of Glasgow and received post-doctoral research training in various laboratories before joining Professor Dominiczak’s group. My principle research interests include identification of genetic determinants underlying complex disease, including hypertension and stroke, in experimental genetics and medicine. I have established microarray gene expression profiling on both the Affymetrix and Illumina platforms, microRNA profiling and have generated some high through put proteomics data with collaborators in the Sir Henry Wellcome Functional Genomics Facility, University of Glasgow. As well as an interest in identifying disrupted biological pathways from this data I have a major interest to integrate all three levels of biological information. Through external collaborations I work closely with bioinformaticians in Glasgow, Edinburgh and Imperial College, London and have particularly strong links with Ensembl.

Through the Euratools consortium, I was invited to present at a key note lecture at the Cardiovascular Genetics workshop at the European Council for Cardiovascular Research meeting (12th-14th October 2007, La Colle sur Loup, Nice, France). Through my interest in biological pathways and transcriptional networks I was invited to present at the Ingenuity Pathway Analysis User meeting (Basle Switzerland, 2007). In addition, I am a member of the British Hypertension Society and have chaired sessions at the International Society of Hypertension Fukuoka, Japan (2006) and various other local meetings.

Research groups

Publications

List by: Type | Date

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Number of items: 78.

2024

Zhou, M., Mary, S. , Delles, C. , Padmanabhan, S. , Graham, D. , McBride, M. W. and Dominiczak, A. (2024) Insights into uromodulin and blood pressure. Current Hypertension Reports, (doi: 10.1007/s11906-024-01317-0) (PMID:39259220) (Early Online Publication)

2023

Camargo, L. L., Wang, Y., Rios, F. J., McBride, M. , Montezano, A. C. and Touyz, R. M. (2023) Oxidative stress and endoplasmic reticular stress interplay in the vasculopathy of hypertension. Canadian Journal of Cardiology, 39(12), pp. 1874-1887. (doi: 10.1016/j.cjca.2023.10.012) (PMID:37875177)

Martin, T. P. et al. (2023) Ribonucleicacid interference or small molecule inhibition of Runx1 in the border zone prevents cardiac contractile dysfunction following myocardial infarction. Cardiovascular Research, 119(16), 2663–2671-2663–2671. (doi: 10.1093/cvr/cvad107) (PMID:37433039) (PMCID:PMC10730241)

Cui, L. et al. (2023) Dominance is common in mammals and is associated with trans-acting gene expression and alternative splicing. Genome Biology, 24(1), 215. (doi: 10.1186/s13059-023-03060-2) (PMID:37773188) (PMCID:PMC10540365)

2022

Mary, S. , Boder, P., Padmanabhan, S. , McBride, M. W. , Graham, D. , Delles, C. and Dominiczak, A. F. (2022) The role of uromodulin in salt-sensitive hypertension. Hypertension, 79, pp. 2419-2429. (doi: 10.1161/HYPERTENSIONAHA.122.19888) (PMID:36378920) (PMCID:PMC9553220)

2021

Scott, K. , Morgan, H. L., Delles, C. , Fisher, S., Graham, D. and McBride, M. W. (2021) Distinct uterine artery gene expression profiles during early gestation in the stroke-prone spontaneously hypertensive rat. Physiological Genomics, 53(4), pp. 160-171. (doi: 10.1152/physiolgenomics.00159.2020) (PMID:33719581)

2020

Riddell, A. , McBride, M. , Braun, T., Nicklin, S. A. , Cameron, E. , Loughrey, C. M. and Martin, T. P. (2020) RUNX1: an emerging therapeutic target for cardiovascular disease. Cardiovascular Research, 116(8), pp. 1410-1423. (doi: 10.1093/cvr/cvaa034) (PMID:32154891) (PMCID:PMC7314639)

Yang, Y. et al. (2020) Endothelial pannexin 1 channels control inflammation by regulating intracellular calcium. Journal of Immunology, 204(11), pp. 2995-3007. (doi: 10.4049/jimmunol.1901089) (PMID:32312847) (PMCID:PMC7336877)

Frazier, S., McBride, M. W. , Mulvana, H. and Graham, D. (2020) From animal models to patients: the role of placental microRNAs, miR-210, miR-126, and miR-148a/152 in preeclampsia. Clinical Science, 134(8), pp. 1001-1025. (doi: 10.1042/CS20200023) (PMID:32337535) (PMCID:PMC7239341)

2019

Olson, E., Pravenec, M., Landa, V., Koh-Tan, H. H. C., Dominiczak, A. F. , McBride, M. W. and Graham, D. (2019) Transgenic overexpression of glutathione S-transferase μ-type 1 reduces hypertension and oxidative stress in the stroke-prone spontaneously hypertensive rat. Journal of Hypertension, 37(5), pp. 985-996. (doi: 10.1097/HJH.0000000000001960) (PMID:30308595)

2018

Graham, L. A., Aman, A. , Campbell, D. D. , Augley, J., Graham, D. , McBride, M. W. , Fraser, N. J., Ferreri, N. R., Dominiczak, A. F. and Padmanabhan, S. (2018) Salt stress in the renal tubules is linked to TAL specific expression of uromodulin and an upregulation of heat shock genes. Physiological Genomics, 50(11), pp. 964-972. (doi: 10.1152/physiolgenomics.00057.2018) (PMID:30216136) (PMCID:PMC6293113)

Morgan, H. L., Butler, E., Ritchie, S., Herse, F., Dechend, R., Beattie, E., McBride, M. W. and Graham, D. (2018) Modeling superimposed preeclampsia using Ang II (Angiotensin II) infusion in pregnant stroke-prone spontaneously hypertensive rats. Hypertension, 72(1), pp. 208-218. (doi: 10.1161/HYPERTENSIONAHA.118.10935) (PMID:29844145) (PMCID:PMC6012051)

Bailey, E. , McBride, M. W. , McClure, J. D. , Beattie, W., Graham, D. , Dominiczak, A. , Smith, C. and Wardlaw, J. (2018) Effects of dietary salt on gene and protein expression in brain tissue of a model of sporadic small vessel disease. Clinical Science, 132(12), pp. 1315-1328. (doi: 10.1042/CS20171572) (PMID:29632138) (PMCID:PMC6365623)

McCarroll, C. S. et al. (2018) Runx1 deficiency protects against adverse cardiac remodeling after myocardial infarction. Circulation, 137(1), pp. 57-70. (doi: 10.1161/CIRCULATIONAHA.117.028911) (PMID:29030345) (PMCID:PMC5757664)

2017

Small, H. Y., Akehurst, C., Sharafetdinova, L., McBride, M. W. , McClure, J. D. , Robinson, S. W., Carty, D. M., Freeman, D. J. and Delles, C. (2017) HLA gene expression is altered in whole blood and placenta from women who later developed preeclampsia. Physiological Genomics, 49(3), pp. 193-200. (doi: 10.1152/physiolgenomics.00106.2016) (PMID:28130428) (PMCID:PMC5374453)

Koh-Tan, H.H. C., Dashti, M., Wang, T., Beattie, W., Mcclure, J. , Young, B., Dominiczak, A. F. , McBride, M. W. and Graham, D. (2017) Dissecting the genetic components of a quantitative trait locus for blood pressure and renal pathology on rat chromosome 3. Journal of Hypertension, 35(2), pp. 319-329. (doi: 10.1097/HJH.0000000000001155) (PMID:27755386) (PMCID:PMC5214373)

Tsiropoulou, S., McBride, M. and Padmanabhan, S. (2017) Urine metabolomics in hypertension research. In: Touyz, R. M. and Schiffrin, E. L. (eds.) Hypertension: Methods and Protocols. Series: Methods in molecular biology, 1527. Springer: New York, pp. 61-68. ISBN 9781493966233 (doi: 10.1007/978-1-4939-6625-7_5)

2016

Morgan, H., Small, H.Y., Beattie, E., McBride, M.W. and Graham, D. (2016) [OP.5D.02] Transcriptomic changes in early pregnancy-associated uterine artery remodelling in stroke prone spontaneously hypertensive rat. Journal of Hypertension, 34(S2), e63-e63. (doi: 10.1097/01.hjh.0000491501.79443.05) (PMID:27508758)

Ballantyne, M. D. et al. (2016) Smooth muscle enriched long noncoding RNA (SMILR) regulates cell proliferation. Circulation, 133(21), pp. 2050-2065. (doi: 10.1161/circulationaha.115.021019) (PMID:27052414) (PMCID:PMC4872641)

Durussel, J. et al. (2016) Blood transcriptional signature of recombinant human erythropoietin administration and implications for antidoping strategies. Physiological Genomics, 48(3), pp. 202-209. (doi: 10.1152/physiolgenomics.00108.2015) (PMID:26757800)

Boulberdaa, M. et al. (2016) A role for the long non-coding RNA SENCR in commitment and function of endothelial cells. Molecular Therapy, 24(5), pp. 978-990. (doi: 10.1038/mt.2016.41) (PMID:26898221) (PMCID:PMC4876031)

2015

Deng, L. et al. (2015) MicroRNA-143 activation regulates smooth muscle and endothelial cell crosstalk in pulmonary arterial hypertension. Circulation Research, 117(10), pp. 870-883. (doi: 10.1161/CIRCRESAHA.115.306806) (PMID:26311719) (PMCID:PMC4620852)

Akehurst, C. et al. (2015) Differential expression of microRNA-206 and its target genes in pre-eclampsia. Journal of Hypertension, 33(10), pp. 2068-2074. (doi: 10.1097/HJH.0000000000000656) (PMID:26213997) (PMCID:PMC4570688)

Menni, C. et al. (2015) Metabolomic identification of a novel pathway of blood pressure regulation involving hexadecanedioate. Hypertension, 66, pp. 422-429. (doi: 10.1161/HYPERTENSIONAHA.115.05544) (PMID:26034203) (PMCID:PMC4490909)

McDonald, R. A. et al. (2015) Reducing in-stent restenosis therapeutic manipulation of miRNA in vascular remodeling and inflammation. Journal of the American College of Cardiology, 65(21), pp. 2314-2327. (doi: 10.1016/j.jacc.2015.03.549) (PMID:26022821) (PMCID:PMC4444526)

Skogstrand, T., Leh, S., McClure, J. , Dashti, M., Iversen, B. M., Graham, D. , McBride, M. and Hultström, M. (2015) Identification of a common molecular pathway in hypertensive renal damage. Journal of Hypertension, 33(3), pp. 584-596. (doi: 10.1097/HJH.0000000000000395) (PMID:25380151)

Lopez, L. M. et al. (2015) Genes from a translational analysis support a multifactorial nature of white matter hyperintensities. Stroke, 46(2), pp. 341-347. (doi: 10.1161/STROKEAHA.114.007649) (PMID:25586835) (PMCID:PMC4306534)

2014

Sampson, A. K., Mohammed, D., Beattie, W., Graham, D. , Kenyon, C. J., Al-Dujaili, E. A.S., Guryev, V., McBride, M. W. and Dominiczak, A. F. (2014) Introgressed chromosome 2 quantitative trait loci restores aldosterone regulation and reduces response to salt in the stroke-prone spontaneously hypertensive rat. Journal of Hypertension, 32(10), pp. 2013-2021. (doi: 10.1097/HJH.0000000000000300)

Graham, L. A. et al. (2014) Validation of uromodulin as a candidate gene for human essential hypertension. Hypertension, 63(3), pp. 551-558. (doi: 10.1161/HYPERTENSIONAHA.113.01423)

Bailey, E. L. , McBride, M. W. , Crawford, W., McClure, J. D. , Graham, D. , Dominiczak, A. F. , Sudlow, C. L.M., Smith, C. and Wardlaw, J. M. (2014) Differential gene expression in multiple neurological, inflammatory and connective tissue pathways in a spontaneous model of human small vessel stroke. Neuropathology and Applied Neurobiology, 40(7), pp. 855-872. (doi: 10.1111/nan.12116)

Baud, A. et al. (2014) Genomes and phenomes of a population of outbred rats and its progenitors. Scientific Data, 1, 140011. (doi: 10.1038/sdata.2014.11) (PMID:25977769) (PMCID:PMC4381735)

Padmanabhan, S. , Graham, L., Ferreri, N. R., Graham, D. , McBride, M. and Dominiczak, A. (2014) Uromodulin, an emerging novel pathway for blood pressure regulation and hypertension. Hypertension, 64(5), pp. 918-923. (doi: 10.1161/HYPERTENSIONAHA.114.03132)

Sampson, A. K., Andrews, K. L., Graham, D. , McBride, M. W. , Head, G. A., Thomas, M. C., Chin-Dusting, J. P.F., Dominiczak, A. F. and Jennings, G. L. (2014) Origin of the y chromosome influences intrarenal vascular responsiveness to angiotensin i and angiotensin (1-7) in stroke-prone spontaneously hypertensive rats. Hypertension, 64(6), pp. 1376-1383. (doi: 10.1161/HYPERTENSIONAHA.114.03756)

2013

Ramdas, V., McBride, M. , Denby, L. and Baker, A. H. (2013) Canonical transforming growth factor-β signaling regulates disintegrin metalloprotease expression in experimental renal fibrosis via miR-29. American Journal of Pathology, 183(6), pp. 1885-1896. (doi: 10.1016/j.ajpath.2013.08.027)

Atanur, S.S. et al. (2013) Genome sequencing reveals loci under artificial selection that underlie disease phenotypes in the laboratory rat. Cell, 154(3), pp. 691-703. (doi: 10.1016/j.cell.2013.06.040)

Baud, A. et al. (2013) Combined sequence-based and genetic mapping analysis of complex traits in outbred rats. Nature Genetics, 45(7), pp. 767-775. (doi: 10.1038/ng.2644)

Howard, L., MacKenzie, R. M., Pchelintsev, N. A., McBryan, T., McClure, J. D. , McBride, M. W. , Kane, N. M., Adams, P. D., Milligan, G. and Baker, A. H. (2013) Profiling of transcriptional and epigenetic changes during directed endothelial differentiation of human embryonic stem cells identifies FOXA2 as a marker of early mesoderm commitment. Stem Cell Research and Therapy, 4(2), Art. 36. (doi: 10.1186/scrt192)

Koh-Tan, H.H. C., McBride, M. W. , McClure, J. D. , Beattie, E., Young, B., Dominiczak, A. F. and Graham, D. (2013) Interaction between chromosome 2 and 3 regulates pulse pressure in the stroke-prone spontaneously hypertensive rat. Hypertension, 62(1), pp. 33-40. (doi: 10.1161/HYPERTENSIONAHA.111.00814)

2012

MacKenzie, R.M., Sandrim, V.C., Carty, D.M., McClure, J.D. , Freeman, D.J. , Dominiczak, A.F. , McBride, M.W. and Delles, C. (2012) Endothelial FOS expression and pre-eclampsia. BJOG: An International Journal of Obstetrics and Gynaecology, 119(13), pp. 1564-1571. (doi: 10.1111/1471-0528.12016)

2011

Nash, B., Thomson, C.E., Linington, C. , Arthur, A.T., McClure, J.D. , McBride, M.W. and Barnett, S.C. (2011) Functional duality of astrocytes in myelination. Journal of Neuroscience, 31(37), pp. 13028-13038. (doi: 10.1523/JNEUROSCI.1449-11.2011)

Denby, L. et al. (2011) miR-21 and miR-214 are consistently modulated during renal injury in rodent models. American Journal of Pathology, 179(2), pp. 661-672. (doi: 10.1016/j.ajpath.2011.04.021)

Yogi, A., Callera, G.E., Aranha, A.B., Antunes, T.T., Graham, D. , McBride, M. , Dominiczak, A. and Touyz, R.M. (2011) Sphingosine-1-Phosphate-Induced Inflammation Involves Receptor Tyrosine Kinase Transactivation in Vascular Cells: Upregulation in Hypertension. Hypertension, 57(4), pp. 809-818. (doi: 10.1161/HYPERTENSIONAHA.110.162719)

2010

Hopcroft, L. E.M. , McBride, M. W. , Harris, K. J., Sampson, A. K., McClure, J. D. , Graham, D. , Young, G., Holyoake, T. L., Girolami, M. A. and Dominiczak, A. F. (2010) Predictive response-relevant clustering of expression data provides insights into disease processes. Nucleic Acids Research, 38(20), pp. 6831-6840. (doi: 10.1093/nar/gkq550)

Craig, M. A., McBride, M. W. , Smith, G., George, S. and Baker, A. (2010) Dysregulation of cadherins in the intercalated disc of the spontaneously hypertensive stroke-prone rat. Journal of Molecular and Cellular Cardiology, 48(6), pp. 1121-1128. (doi: 10.1016/j.yjmcc.2010.01.017)

Delles, C. , McBride, M.W. , Graham, D. , Padmanabhan, S. and Dominiczak, A.F. (2010) Genetics of hypertension: from experimental animals to humans. Biochimica et Biophysica Acta: Molecular Basis of Disease, 1802(12), pp. 1299-1308. (doi: 10.1016/j.bbadis.2009.12.006)

Fairley, S., McClure, J. , Hanlon, N., Irving, R., McBride, M. , Dominiczak, A. and Hunt, E. (2010) Mapping affymetrix microarray probes to the rat genome via a persistent index. International Journal of Knowledge Discovery in Bioinformatics, 1(1), pp. 48-65. (doi: 10.4018/jkdb.2010100204)

McBride, M. , Hopcroft, L. , Harris, K., McClure, J. , Graham, D. , Girolami, M. and Dominiczak, M. (2010) Insights into Salt-Sensitive Hypertension Using Response-Relevant Clustering. In: 20th Annual Meeting of the European Society of Hypertension, Oslo, Norway, 18-21 June, E342-E342.

Padmanabhan, S. et al. (2010) Genome-wide association study of blood pressure extremes identifies variant near UMOD associated with hypertension. PLoS Genetics, 6(10), e1001177. (doi: 10.1371/journal.pgen.1001177)

Taurino, C., Miller, W.H. , McBride, M.W. , McClure, J.D. , Khanin, R., Moreno Zulategui, M.U., Dymott, J., Delles, C. and Dominiczak, A.F. (2010) Gene expression profiling in whole blood of patients with coronary artery disease. Clinical Science, 119(8), pp. 335-343. (doi: 10.1042/CS20100043)

2009

Methven, L., McBride, M. , Wallace, G.A. and McGrath, J.C. (2009) The α1B/D-adrenoceptor knockout mouse permits isolation of the vascular α1A-adrenoceptor and elucidates its relationship to the other subtypes. British Journal of Pharmacology, 158(1), pp. 209-224. (doi: 10.1111/j.1476-5381.2009.00269.x) (PMID:19572943) (PMCID:PMC2795267)

Padmanabhan, S. , Hastie, C. , Sainsbury, C., McBride, M. W. , Connell, J. M. and Dominiczak, A. F. (2009) The cat, the fly and the beetle - why genetics needs a semantic education. International Journal of Semantic Computing, 3(1), pp. 77-90. (doi: 10.1142/S1793351X09000665)

Koh-Tan, H., Graham, D. , Hamilton, C., Nicoll, G., Fields, L., McBride, M. , Young, B., Young, B. and Dominiczak, A. (2009) Renal and vascular glutathione S-transferase mu is not affected by pharmacological intervention to reduce systolic blood pressure. Journal of Hypertension, 27(8), pp. 1575-1584. (doi: 10.1097/HJH.0b013e32832cc5a1)

Masson, R. et al. (2009) Onset of experimental severe cardiac fibrosis is mediated by overexpression of angiotensin-converting enzyme 2. Hypertension, 53(4), pp. 694-700. (doi: 10.1161/HYPERTENSIONAHA.108.122333)

2008

Delles, C., McBride, M.W., Padmanabhan, S. and Dominiczak, A.F. (2008) The genetics of cardiovascular disease. Trends in Endocrinology and Metabolism, 19(9), pp. 309-316. (doi: 10.1016/j.tem.2008.07.010)

Delles, C. et al. (2008) Glutathione S-transferase variants and hypertension. Journal of Hypertension, 26(7), pp. 1343-1352. (doi: 10.1097/HJH.0b013e3282fe1d67)

Tian, T., McBride, M.W., Graham, D., Touyz, R. and Dominiczak, A.F. (2008) A systems biology approach for the sphingosine-1-phosphate signal transduction in vascular smooth muscle cell. Journal of Hypertension, 26(Suppl.), S148-S148.

Tonyz, R., Aranha, A., Yogi, A., Graham, D., McBride, M., Callera, G., Montezano, A., Coimbra, T. and Dominiczak, A. (2008) Increased vascular sphingosine-1-phosphate signaling in SHRSP is due to post-receptor mechanisms. Journal of Hypertension, 26(Suppl.), S329-S329.

2007

Graham, D. et al. (2007) Candidate genes that determine response to salt in the stroke-prone spontaneously hypertensive rat - Congenic analysis. Hypertension, 50(6), pp. 1134-1141. (doi: 10.1161/HYPERTENSIONAHA.107.095349)

Jakubowska, J., Hunt, E., Chalmers, M., McBride, M. and Dominiczak, A. F. (2007) VisGenome: visualization of single and comparative genome representations. Bioinformatics, 23(19), pp. 2641-2642. (doi: 10.1093/bioinformatics/btm394)

2006

McBride, M. , Graham, D., Delles, C. and Dominiczak, A. (2006) Functional genomics in hypertension. Current Opinion in Nephrology and Hypertension, 15(2), pp. 145-151. (doi: 10.1097/01.mnh.0000203188.57513.3f)

2005

Ye, P. et al. (2005) The aldosterone synthase (CYP11B2) and 11 beta-hydroxylase (CYP11B1) genes are not expressed in the rat heart. Endocrinology, 146(12), pp. 5287-5293. (doi: 10.1210/en.2005-0370) (PMID:16179417)

Jakubowska, J., Hunt, E., Chalmers, M. , Leader, D. , McBride, M. and Dominiczak, A. F. (2005) System level visualization of eQTLs and pQTLs. BMC Bioinformatics, 6(Sup 3), P15. (doi: 10.1186/1471-2105-6-S3-P15)

Adler, J., Arribas, S., Briones, A., Daly, C., Deighan, C., McBride, M. , McGrath, J. , Shafaroudi, M. and Vila, E. (2005) New aspects of vascular remodelling: the involvement of all vascular cell types. Experimental Physiology, 90, pp. 469-475. (doi: 10.1113/expphysiol.2005.030130)

Daly, C., Deighan, C., Macmillan, J., McBride, M. , McGrath, J., Shafaroudi, M. and Wokoma, A. (2005) Two 'knockout' mouse models demonstrate that aortic vasodilatation is mediated via alpha(2A)-adrenoceptors located on the endothelium. Journal of Pharmacology and Experimental Therapeutics, 314(2), pp. 804-810.

Dominiczak, A. F., Graham, D. , McBride, M. W. , Brain, N. J.R., Lee, W. K. , Charchar, F. J., Tomaszewski, M., Delles, C. and Hamilton, C. A. (2005) Corcoran Lecture. Cardiovascular genomics and oxidative stress. Hypertension, 45(4), pp. 636-642. (doi: 10.1161/01.HYP.0000154253.53134.09)

McBride, M. et al. (2005) Reduction of Gstm1 expression in the stroke-prone spontaneously hypertension rat contributes to increased oxidative stress. Hypertension, 45(4), pp. 786-792. (doi: 10.1161/01.HYP.0000154879.49245.39)

Shafaroudi, M., McBride, M. , Deighan, C., Wokoma, A., Macmillan, J., Daly, C. and McGrath, J. (2005) Two "knockout" mouse models demonstrate that aortic vasodilatation is mediated via alpha(2A)-adrenoceptors located on the endothelium. Journal of Pharmacology and Experimental Therapeutics, 314, pp. 804-810. (doi: 10.1124/jpet.105.085944)

Strahorn, P., Graham, D., Charchar, F., Sattar, N. , McBride, M. and Dominiczak, A. (2005) Genetic determinants of metabolic syndrome components in the stroke-prone spontaneously hypertensive rat. Journal of Hypertension, 23(12), pp. 2179-2186.

2004

McBride, M.W. , Charchar, F.J., Graham, D. , Miller, W.H. , Strahorn, P., Carr, F.J. and Dominiczak, A.F. (2004) Functional genomics in rodent models of hypertension. Journal of Physiology, 554(1), pp. 56-63. (doi: 10.1113/jphysiol.2003.049361)

Dominiczak, A. , Brain, N., Charchar, F., McBride, M. , Hanlon, N. and Lee, W. (2004) Genetics of hypertension: Lessons learnt from Mendelian and polygenic syndromes. Clinical and Experimental Hypertension, 26(7-8), pp. 611-620. (doi: 10.1081/CEH-200031939)

Hamilton, C., Miller, W., Al Benna, S., Brosnan, M., Drummond, R., McBride, M. and Dominiczak, A. (2004) Strategies to reduce oxidative stress in cardiovascular disease. Clinical Science, 106, pp. 219-234. (doi: 10.1042/CS20030379)

2003

Dominiczak, A.F. and McBride, M.W. (2003) Genetics of common polygenic stroke. Nature Genetics, 35(2), pp. 116-117.

McBride, M. , Carr, F., Graham, D., Anderson, N., Clark, J., Lee, W., Charchar, F., Brosnan, M. and Dominiczak, A. (2003) Microarray analysis of rat chromosome 2 congenic strains. Hypertension, 41, pp. 847-853. (doi: 10.1161/01.HYP.0000047103.07205.03)

2002

Ali, Z., Daly, C., Deighan, C., McBride, M. , McGee, A., McGrath, J. and Mennie, D. (2002) A knockout approach indicates a minor vasoconstrictor role for vascular alpha(1B)-adrenoceptors in mouse. Physiological Genomics, 9, pp. 85-91. (doi: 10.1152/physiolgenomics.00065.2001)

Carr, F.J., Negrin, C.D., Clark, J.S., Graham, D., McBride, M.W. , Anderson, N.W. and Dominiczak, A.F. (2002) Chromosome 2 reciprocal congenic strains to evaluate the effect of the genetic background on blood pressure. Scottish Medical Journal, 47(1), pp. 7-9. (doi: 10.1177/003693300204700104)

Carr, F., McBride, M. , Carswell, H., Graham, D., Strahorn, P., Clark, J., Charchar, F. and Dominiczak, A. (2002) Genetic aspects of stroke: Human and experimental studies. Journal of Cerebral Blood Flow and Metabolism, 22(7), pp. 767-773. (doi: 10.1097/00004647-200207000-00001)

McBride, M. , Carswell, H., Graham, D., Carr, F., Charchar, F., Macrae, I. and Dominiczak, A. (2002) Genetic and gender determinants of cerebrovascular disease. Seminars in Nephrology, 22, pp. 127-134. (doi: 10.1053/snep.2002.30213)

2001

Negrin, C., McBride, M. , Carswell, H., Graham, D., Carr, F., Clark, J., Jeffs, B., Anderson, N., Macrae, I. and Dominiczak, A. (2001) Reciprocal consomic strains to evaluate Y chromosome effects. Hypertension, 37, pp. 391-397. (doi: 10.1161/01.HYP.37.2.391)

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Number of items: 78.

Articles

Graham, L. A. et al. (2014) Validation of uromodulin as a candidate gene for human essential hypertension. Hypertension, 63(3), pp. 551-558. (doi: 10.1161/HYPERTENSIONAHA.113.01423)

Baud, A. et al. (2014) Genomes and phenomes of a population of outbred rats and its progenitors. Scientific Data, 1, 140011. (doi: 10.1038/sdata.2014.11) (PMID:25977769) (PMCID:PMC4381735)

Baud, A. et al. (2013) Combined sequence-based and genetic mapping analysis of complex traits in outbred rats. Nature Genetics, 45(7), pp. 767-775. (doi: 10.1038/ng.2644)

Denby, L. et al. (2011) miR-21 and miR-214 are consistently modulated during renal injury in rodent models. American Journal of Pathology, 179(2), pp. 661-672. (doi: 10.1016/j.ajpath.2011.04.021)

Delles, C. et al. (2008) Glutathione S-transferase variants and hypertension. Journal of Hypertension, 26(7), pp. 1343-1352. (doi: 10.1097/HJH.0b013e3282fe1d67)

Dominiczak, A.F. and McBride, M.W. (2003) Genetics of common polygenic stroke. Nature Genetics, 35(2), pp. 116-117.

Book Sections

Conference Proceedings

This list was generated on Thu Nov 21 02:34:47 2024 GMT.

Grants

Grants and Awards listed are those received whilst working with the University of Glasgow.

Investigating the Therapeutic Potential of Runx1 for Myocardial Infarction
British Heart Foundation
2018 - 2022
ISSF Catalyst: Global regulation of gene expression in the Thick Ascending Limb of the Loop of Henle by TNF: implications for salt-uptake and blood pressure regulation
Wellcome Trust
2016 - 2017
INVESTIGATING THE ROLE OF RUNX1 IN THE HEART POST-MYOCARDIAL INFARCTION
Medical Research Council
2015 - 2018
Investigation of Osteopontin as a candidate gene for left ventricular hypertrophy
British Heart Foundation
2014 - 2018
A systems biology biomarkers approach to the differentiation of recombinant human erythropoietin doping from confounding factors
World Anti-Doping Agency
2014 - 2015
Genetic, molecular and functional dissection of a novel pathway for hypertension: Uromodulin, renal function, sodium homeostasis and blood pressure.
British Heart Foundation
2013 - 2017
Genomics and proteomics of hypertension and its vascular complications: the pathwayomic strategies.
British Heart Foundation
2008 - 2011

Supervision

Black, Iain
Investigating the mechanisms of acute preservation of cardiac function post-MI following angiotensin-(1-9) gene therapy

Research datasets

Jump to: 2016

Number of items: 1.

2016

Skogstrand, T., Leh, S., McClure, J. , Dashti, M., Iversen, B. M., Graham, D. , McBride, M. and Hultstom, M. (2016) Identification of a common molecular pathway in hypertensive renal damage: comparison of rat and human gene expression profiles. [Data Collection]

This list was generated on Thu Nov 21 01:17:20 2024 GMT.

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Dr Martin McBride

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