Professor David Stott J
- Honorary Senior Research Fellow (School of Cardiovascular & Metabolic Health)
email:
David.J.Stott@glasgow.ac.uk
Room 2.42, 2nd Floor New Lister Building, Glasgow Royal Infirmary, G31 2er
Publications
2024
de Vries, P. S. et al. (2024) A genetic association study of circulating coagulation Factor VIII and von Willebrand Factor levels. Blood, (doi: 10.1182/blood.2023021452) (PMID:38320121) (Early Online Publication)
Sterenborg, R. B. T. M. et al. (2024) Multi-trait analysis characterizes the genetics of thyroid function and identifies causal associations with clinical implications. Nature Communications, 15, 888. (doi: 10.1038/s41467-024-44701-9) (PMID:38291025) (PMCID:PMC10828500)
2023
Zonneveld, M. H., Noordam, R., Sabayan, B., Stott, D. J. , Mooijaart, S. P., Blauw, G. J., Jukema, J. W., Sattar, N. and Trompet, S. (2023) Weight loss, visit-to-visit body weight variability and cognitive function in older individuals. Age and Ageing, 52(1), afac312. (doi: 10.1093/ageing/afac312) (PMID:36626325)
2022
Lahti, J. et al. (2022) Genome-wide meta-analyses reveal novel loci for verbal short-term memory and learning. Molecular Psychiatry, 27(11), pp. 4419-4431. (doi: 10.1038/s41380-022-01710-8) (PMID:35974141) (PMCID:PMC9734053)
Du Puy, R. S. et al. (2022) No effect of levothyroxine on hemoglobin in older adults with subclinical hypothyroidism: pooled results from 2 randomized controlled trials. Journal of Clinical Endocrinology and Metabolism, 107(6), e2339-e2347. (doi: 10.1210/clinem/dgac106) (PMID:35218666)
Taylor-Rowan, M. , McGuire, L. , Hafdi, M., Evans, J. , Stott, D. J. , Wetherall, K., Elliott, E., Drozdowska, B. and Quinn, T. J. (2022) Comparative validity of informant tools for assessing pre-stroke cognitive impairment. International Journal of Geriatric Psychiatry, 37(4), pp. 1-10. (doi: 10.1002/gps.5700) (PMID:35278006)
2021
Hasemann, W. et al. (2021) Comparing performance on the months of the year backwards test in hospitalised patients with delirium, dementia and no cognitive impairment: an exploratory study. European Geriatric Medicine, 12(6), pp. 1257-1265. (doi: 10.1007/s41999-021-00521-4) (PMID:34156656)
Lumbers, R. T. et al. (2021) The genomics of heart failure: design and rationale of the HERMES consortium. ESC Heart Failure, 8(6), pp. 5531-5541. (doi: 10.1002/ehf2.13517) (PMID:34480422) (PMCID:PMC8712846)
Schunk, S. J. et al. (2021) Genetically determined NLRP3 inflammasome activation associates with systemic inflammation and cardiovascular mortality. European Heart Journal, 42(18), pp. 1742-1756. (doi: 10.1093/eurheartj/ehab107) (PMID:33748830)
2020
Sargurupremraj, M. et al. (2020) Cerebral small vessel disease genomics and its implications across the lifespan. Nature Communications, 11, 6285. (doi: 10.1038/s41467-020-19111-2) (PMID:33293549) (PMCID:PMC7722866)
Stuber, M. J. et al. (2020) Effect of thyroid hormone therapy on fatigability in older adults with subclinical hypothyroidism: a nested study within a randomized placebo-controlled trial. Journals of Gerontology Series A: Biological Sciences and Medical Sciences, 75(9), e89-e94. (doi: 10.1093/gerona/glaa123) (PMID:32577745) (PMCID:PMC7494024)
Gencer, B. et al. (2020) The impact of Levothyroxine on cardiac function in older adults with Mild subclinical hypothyroidism: a randomized clinical trial. American Journal of Medicine, 133(7), 848-856.e5. (doi: 10.1016/j.amjmed.2020.01.018) (PMID:32171774)
de Montmollin, M. et al. (2020) L-thyroxine therapy for older adults with subclinical hypothyroidism and hypothyroid symptoms: secondary analysis of a randomized trial. Annals of Internal Medicine, 172(11), pp. 709-716. (doi: 10.7326/M19-3193) (PMID:32365355)
Burton, J. K. , Yates, L. C., Whyte, L., Fitzsimmons, E. and Stott J, D. (2020) New horizons in iron deficiency anaemia in older adults. Age and Ageing, 49(3), pp. 309-318. (doi: 10.1093/ageing/afz199)
Zijlstra, L. E., Trompet, S., Mooijaart, S. P., van Buren, M., Sattar, N. , Stott, D. J. and Jukema, J. W. (2020) The association of kidney function and cognitive decline in older patients at risk of cardiovascular disease: a longitudinal data analysis. BMC Nephrology, 21, 81. (doi: 10.1186/s12882-020-01745-5) (PMID:32138689) (PMCID:PMC7059260)
Baylan, S. et al. (2020) Measuring the Effects of Listening for Leisure on Outcome after stroke (MELLO): a pilot randomised controlled trial of mindful music listening. International Journal of Stroke, 15(2), pp. 149-158. (doi: 10.1177/1747493019841250) (PMID:30940047) (PMCID:PMC7045280)
Tieges, Z. et al. (2020) A smartphone-based test for the assessment of attention deficits in delirium: a case-control diagnostic test accuracy study in older hospitalised patients. PLoS ONE, 15(1), e0227471. (doi: 10.1371/journal.pone.0227471) (PMID:31978127) (PMCID:PMC6980392)
Zijlstra, L.E., van Velzen, D.M., Simsek, S., Mooijaart, S.P., van Buren, M., Stott J, D.J. , Ford, I. , Jukema, J. and Trompet, S. (2020) The kidney, subclinical thyroid disease and cardiovascular outcomes in older patients. Endocrine Connections, 9(1), pp. 55-62. (doi: 10.1530/EC-19-0502) (PMID:31846431) (PMCID:PMC6993270)
2019
de las Fuentes, L. et al. (2019) Genome-wide meta-analysis of variant-by-diuretic interactions as modulators of lipid traits in persons of European and African ancestry. Pharmacogenomics Journal, 20(3), pp. 482-493. (doi: 10.1038/s41397-019-0132-y) (PMID:31806883) (PMCID:PMC7260079)
Irvin, M. R. et al. (2019) Genome wide association study of apparent treatment resistant hypertension in the CHARGE consortium: the CHARGE pharmacogenetics working group. American Journal of Hypertension, 32(12), pp. 1146-1153. (doi: 10.1093/ajh/hpz150) (PMID:31545351)
Mooijaart, S. P. et al. (2019) Association between levothyroxine treatment and thyroid-related symptoms among adults aged 80 years and older with subclinical hypothyroidism. JAMA: Journal of the American Medical Association, 322(20), pp. 1977-1986. (doi: 10.1001/jama.2019.17274) (PMID:31664429)
Shaw, R., Drozdowska, B. , Taylor-Rowan, M. , Elliott, E., Cuthbertson, G., Stott, D. J. and Quinn, T. J. (2019) Delirium in an acute stroke setting, occurrence, and risk factors. Stroke, 50(11), pp. 3265-3268. (doi: 10.1161/strokeaha.119.025993) (PMID:31554500)
Kitas, G. D. et al. (2019) A multicenter, randomized, placebo‐controlled trial of atorvastatin for the primary prevention of cardiovascular events in patients with rheumatoid arthritis. Arthritis and Rheumatology, 71(9), pp. 1437-1449. (doi: 10.1002/art.40892) (PMID:30983166) (PMCID:PMC6771601)
Malik, R. et al. (2019) Publisher Correction: Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes. Nature Genetics, (doi: 10.1038/s41588-019-0449-0) (PMID:31160810)
Tsiachristas, A., Ellis, G., Buchanan, S., Langhorne, P. , Stott J, D. and Shepperd, S. (2019) Should I stay or should I go? A retrospective propensity score-matched analysis using administrative data of hospital-at-home for older people in Scotland. BMJ Open, 9, e023350. (doi: 10.1136/bmjopen-2018-023350) (PMID:31072849) (PMCID:PMC6527981)
Taylor-Rowan, M. , Keir, R., Cuthbertson, G., Shaw, R., Drozdowska, B. , Elliott, E., Evans, J. , Stott J, D. and Quinn, T. J. (2019) Pre-stroke frailty is independently associated with post-stroke cognition: A cross-sectional study. Journal of the International Neuropsychological Society, 25(5), pp. 501-506. (doi: 10.1017/S1355617719000092) (PMID:30821222)
Meuwese, C. L. et al. (2019) Low thyroid function is not associated with an accelerated deterioration in renal function. Nephrology Dialysis Transplantation, 34(4), pp. 650-659. (doi: 10.1093/ndt/gfy071) (PMID:29684213)
Patel, R. S. et al. (2019) Association of chromosome 9p21 with subsequent coronary heart disease events: a GENUIS-CHD study of individual participant data. Circulation: Genomic and Precision Medicine, 12(4), e002471. (doi: 10.1161/CIRCGEN.119.002471) (PMID:30897348)
Patel, R. et al. (2019) Subsequent event risk in individuals with established coronary heart disease: design and rationale of the GENIUS-CHD Consortium. Circulation: Genomic and Precision Medicine, (doi: 10.1161/CIRCGEN.119.002470) (PMID:30896328)
Hendry, K., Green, C., McShane, R., Noel-Storr, A. H., Stott J, D. J. , Anwer, S., Sutton, A. J., Burton, J. K. and Quinn, T. J. (2019) AD-8 for detection of dementia across a variety of healthcare settings. Cochrane Database of Systematic Reviews, 3, CD011121. (doi: 10.1002/14651858.CD011121.pub2) (PMID:30828783)
Taylor-Rowan, M. , Momoh, O., Ayerbe, L., Evans, J. J. , Stott, D. J. and Quinn, T. J. (2019) Prevalence of pre-stroke depression and its association with post-stroke depression: a systematic review and meta-analysis. Psychological Medicine, 49(4), pp. 685-696. (doi: 10.1017/S0033291718002003) (PMID:30107864)
Larsson, S. C. et al. (2019) Serum magnesium and calcium levels in relation to ischemic stroke. Neurology, 92(9), e944-e950. (doi: 10.1212/WNL.0000000000007001) (PMID:30804065) (PMCID:PMC6404465)
Ellervik, C. et al. (2019) Assessment of the relationship between genetic determinants of thyroid function and atrial fibrillation: a Medelian randomization study. JAMA Cardiology, 4(2), pp. 144-152. (doi: 10.1001/jamacardio.2018.4635) (PMID:30673084) (PMCID:PMC6396813)
Skaaby, T. et al. (2019) Association of alcohol consumption with allergic disease and asthma: a multicenter Mendelian randomization analysis. Addiction, 114(2), pp. 216-225. (doi: 10.1111/add.14438) (PMID:30209858)
Chauhan, G. et al. (2019) Genetic and lifestyle risk factors for MRI-defined brain infarcts in a population-based setting. Neurology, 92(5), e486-e503. (doi: 10.1212/WNL.0000000000006851) (PMID:30651383) (PMCID:PMC6369905)
Adlam, D. et al. (2019) Association of the PHACTR1/EDN1 genetic locus with spontaneous coronary artery dissection. Journal of the American College of Cardiology, 73(1), pp. 58-66. (doi: 10.1016/j.jacc.2018.09.085) (PMID:30621952)
Mahinrad, S. et al. (2019) Spatial QRS-T angle and cognitive decline in older subjects. Journal of Alzheimer's Disease, 67(1), pp. 279-289. (doi: 10.3233/JAD-180633) (PMID:30584139)
Sabater-Lleal, M. et al. (2019) Genome-wide association transethnic meta-analyses identifies novel associations regulating coagulation factor VIII and von Willebrand factor plasma levels. Circulation, 139(5), pp. 620-635. (doi: 10.1161/CIRCULATIONAHA.118.034532) (PMID:30586737) (PMCID:PMC6438386)
Taylor-Rowan, M. , Cuthbertson, G., Keir, R., Shaw, R., Drozdowska, B. , Elliott, E., Stott, D. and Quinn, T. J. (2019) The prevalence of frailty amongst acute stroke patients, and evaluation of method of assessment. Clinical Rehabilitation, 33(10), pp. 1688-1696. (doi: 10.1177/0269215519841417) (PMID:30971115)
2018
Ligthart, S. et al. (2018) Genome analyses of >200,000 individuals identify 58 loci for chronic inflammation and highlight pathways that link inflammation and complex disorders. American Journal of Human Genetics, 103(5), pp. 691-706. (doi: 10.1016/j.ajhg.2018.09.009) (PMID:30388399) (PMCID:PMC6218410)
Teumer, A. et al. (2018) Genome-wide analyses identify a role for SLC17A4 and AADAT in thyroid hormone regulation. Nature Communications, 9, 4455. (doi: 10.1038/s41467-018-06356-1) (PMID:30367059) (PMCID:PMC6203810)
Feller, M. et al. (2018) Association of thyroid hormone therapy with quality of life and thyroid-related symptoms in patients with subclinical hypothyroidism: a systematic review and meta-analysis. JAMA: Journal of the American Medical Association, 320(13), pp. 1349-1359. (doi: 10.1001/jama.2018.13770)
Evangelou, E. et al. (2018) Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits. Nature Genetics, 50, pp. 1412-1425. (doi: 10.1038/s41588-018-0205-x) (PMID:30224653) (PMCID:PMC6284793)
Vojinovic, D. et al. (2018) Genome-wide association study of 23,500 individuals identifies 7 loci associated with brain ventricular volume. Nature Communications, 9, 3945. (doi: 10.1038/s41467-018-06234-w) (PMID:30258056) (PMCID:PMC6158214)
Du Puy, R.S. et al. (2018) Study protocol: a randomised controlled trial on the clinical effects of levothyroxine treatment for subclinical hypothyroidism in people aged 80 years and over. BMC Endocrine Disorders, 18, 67. (doi: 10.1186/s12902-018-0285-8) (PMID:30231866) (PMCID:PMC6146605)
Rutter, L.-M. et al. (2018) Diagnostic test accuracy of a novel smartphone application for the assessment of attention deficits in delirium in older hospitalised patients: a prospective cohort study protocol. BMC Geriatrics, 18, 217. (doi: 10.1186/s12877-018-0901-5) (PMID:30223771) (PMCID:PMC6142423)
van der Laan, S. W. et al. (2018) Genetic susceptibility loci for cardiovascular disease and their impact on atherosclerotic plaques. Circulation: Genomic and Precision Medicine, 11(9), e002115. (doi: 10.1161/CIRCGEN.118.002115)
Blum, M. R. et al. (2018) Impact of thyroid hormone therapy on atherosclerosis in the elderly with subclinical hypothyroidism: a randomized trial. Journal of Clinical Endocrinology and Metabolism, 103(8), pp. 2988-2997. (doi: 10.1210/jc.2018-00279) (PMID:29846630)
Van Setten, J. et al. (2018) PR interval genome-wide association meta-analysis identifies 50 loci associated with atrial and atrioventricular electrical activity. Nature Communications, 9, 2904. (doi: 10.1038/s41467-018-04766-9) (PMID:30046033) (PMCID:PMC6060178)
Makin, S. and Stott, D. J. (2018) Managing blood pressure in older adults. British Medical Journal, 362, k2912. (doi: 10.1136/bmj.k2912) (PMID:29980562)
Baylan, S. et al. (2018) Participants’ experiences of music, mindful music, and audiobook listening interventions for people recovering from stroke. Annals of the New York Academy of Sciences, 1423(1), pp. 349-359. (doi: 10.1111/nyas.13618) (PMID:29727009)
Burton, J. K. , Papworth, R., Haig, C. , McCowan, C. , Ford, I. , Stott, D. J. and Quinn, T. J. (2018) Statin use is not associated with future long-term care admission - extended follow-up of two randomised controlled trials. Drugs and Aging, 35(7), pp. 657-663. (doi: 10.1007/s40266-018-0560-4) (PMID:29916140)
Davies, G. et al. (2018) Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function. Nature Communications, 9, 2098. (doi: 10.1038/s41467-018-04362-x) (PMID:29844566) (PMCID:PMC5974083)
Stott, D. J. and Applegate, W. B. (2018) Perspectives on hypertension treatment in older persons. Age and Ageing, afy055. (doi: 10.1093/ageing/afy055) (PMID:29788159)
Malik, R. et al. (2018) Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes. Nature Genetics, 50(4), pp. 524-537. (doi: 10.1038/s41588-018-0058-3) (PMID:29531354) (PMCID:PMC5968830)
Kendall, M., Cowey, E. , Mead, G., Barber, M., McAlpine, C., Stott, D. J. , Boyd, K. and Murray, S. A. (2018) Outcomes, experiences and palliative care in major stroke: a multicentre, mixed-method, longitudinal study. Canadian Medical Association Journal, 190(9), E238-E246. (doi: 10.1503/cmaj.170604) (PMID:29507155)
Zijlstra, L.E., Jukema, J.W., Mooijaart, S.P., de Vries, M.A., Stott, D.J. , Castro Cabezas, M. and Trompet, S. (2018) Association of complement receptor 1 gene polymorphisms with cognitive function. Physiological Genomics, 50(2), pp. 102-103. (doi: 10.1152/physiolgenomics.00102.2017) (PMID:29212848)
Floyd, J.S. et al. (2018) Large-scale pharmacogenomic study of sulfonylureas and the QT, JT and QRS intervals: CHARGE Pharmacogenomics Working Group. Pharmacogenomics Journal, 18(1), pp. 127-135. (doi: 10.1038/tpj.2016.90) (PMID:27958378) (PMCID:PMC5468495)
2017
Todd, A., Blackley, S., Burton, J. K. , Stott, D. J. , Ely, E. W., Tieges, Z., MacLullich, A. M.J. and Shenkin, S. D. (2017) Reduced level of arousal and increased mortality in adult acute medical admissions: a systematic review and meta-analysis. BMC Geriatrics, 17, 283. (doi: 10.1186/s12877-017-0661-7) (PMID:29216846) (PMCID:PMC5721682)
Baumgartner, C. et al. (2017) Thyroid function within the normal range, subclinical hypothyroidism and the risk of atrial fibrillation. Circulation, 136(22), pp. 2100-2116. (doi: 10.1161/CIRCULATIONAHA.117.028753) (PMID:29061566)
Witham, M. D. and Stott, D. J. (2017) Conducting and reporting trials for older people. Age and Ageing, 46(6), pp. 889-894. (doi: 10.1093/ageing/afx153) (PMID:28985243)
Shepperd, S. et al. (2017) A multi-centre randomised trial to compare the effectiveness of geriatrician-led admission avoidance hospital at home versus inpatient admission. Trials, 18, 491. (doi: 10.1186/s13063-017-2214-y) (PMID:29061154) (PMCID:PMC5653984)
Stott, D. J. , Rodondi, N. and Bauer, D. C. (2017) Thyroid hormone therapy for older adults with subclinical hypothyroidism. New England Journal of Medicine, 377(14), e20. (doi: 10.1056/NEJMc1709989) (PMID:28976862)
Lees, R. A., Hendry, K., Broomfield, N., Stott, D. , Larner, A. J. and Quinn, T. (2017) Cognitive assessment in stroke: feasibility and test properties using differing approaches to scoring of incomplete items. International Journal of Geriatric Psychiatry, 32(10), pp. 1072-1078. (doi: 10.1002/gps.4568) (PMID:27526678)
Wain, L. V. et al. (2017) Novel blood pressure locus and gene discovery using genome-wide association study and expression data sets from blood and the kidney. Hypertension, 70(3), e4-e19. (doi: 10.1161/HYPERTENSIONAHA.117.09438) (PMID:28739976)
Willeit, P. et al. (2017) High-sensitivity cardiac troponin concentration and risk of first-ever cardiovascular outcomes: literature-based meta-analysis involving 154,052 participants. Journal of the American College of Cardiology, 70(5), pp. 558-568. (doi: 10.1016/j.jacc.2017.05.062) (PMID:28750699) (PMCID:PMC5527070)
Aubert, C. E. et al. (2017) Thyroid function tests in the reference range and fracture: individual participant analysis of prospective cohorts. Journal of Clinical Endocrinology and Metabolism, 102(8), pp. 2719-2728. (doi: 10.1210/jc.2017-00294) (PMID:28482002)
Stott, D. J. et al. (2017) Thyroid hormone therapy for older adults with subclinical hypothyroidism. New England Journal of Medicine, 376(26), pp. 2534-2544. (doi: 10.1056/NEJMoa1603825) (PMID:28402245)
Kendall, M., Cowey, E. , Murray, S.A., Barber, M., Borthwick, S., Boyd, K., McAlpine, C., Stott, D. and Mead, G. (2017) Experiences and Multi-Dimensional Needs of People With Major Stroke and their Family Carers. British Geriatrics Society Autumn Meeting, Glasgow, UK, 23-25 Nov 2016. i46. (doi: 10.1093/ageing/afx070.162)
Noordam, R. et al. (2017) A genome-wide interaction analysis of tricyclic/tetracyclic antidepressants and RR and QT intervals: a pharmacogenomics study from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium. Journal of Medical Genetics, 54(5), pp. 313-323. (doi: 10.1136/jmedgenet-2016-104112) (PMID:28039329)
Stott, D. J. and Young, J. (2017) 'Across the pond'—a response to the NICE guidelines for management of multi-morbidity in older people. Age and Ageing, 46(3), pp. 343-345. (doi: 10.1093/ageing/afx031) (PMID:28369219)
Justice, A. E. et al. (2017) Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits. Nature Communications, 8, 14977. (doi: 10.1038/ncomms14977) (PMID:28443625) (PMCID:PMC5414044)
Young, C., Hall, A. M., Gonçalves-Bradley, D. C., Quinn, T. J. , Hooft, L., van Munster, B. C. and Stott, D. J. (2017) Home or foster home care versus institutional long-term care for functionally dependent older people. Cochrane Database of Systematic Reviews, 2017(4), CD009844. (doi: 10.1002/14651858.CD009844.pub2) (PMID:28368550)
Warren, H. R. et al. (2017) Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk. Nature Genetics, 49(3), pp. 403-415. (doi: 10.1038/ng.3768) (PMID:28135244) (PMCID:PMC5972004)
Stott, D. J. et al. (2017) Study protocol; thyroid hormone replacement for untreated older adults with subclinical hypothyroidism - a randomised placebo controlled trial (TRUST). BMC Endocrine Disorders, 17, 6. (doi: 10.1186/s12902-017-0156-8) (PMID:28158982) (PMCID:PMC5291970)
de Vries, P. S. et al. (2017) Comparison of HapMap and 1000 genomes reference panels in a large-scale genome-wide association study. PLoS ONE, 12(1), e0167742. (doi: 10.1371/journal.pone.0167742) (PMID:28107422) (PMCID:PMC5249120)
Hibar, D. P. et al. (2017) Novel genetic loci associated with hippocampal volume. Nature Communications, 8, 13624. (doi: 10.1038/ncomms13624) (PMID:28098162) (PMCID:PMC5253632)
van Rooij, F. J.A. et al. (2017) Genome-wide trans-ethnic meta-analysis Identifies seven genetic loci influencing erythrocyte traits and a role for RBPMS in erythropoiesis. American Journal of Human Genetics, 100(1), pp. 51-63. (doi: 10.1016/j.ajhg.2016.11.016) (PMID:28017375)
Stott J., D. and Quinn, T. J. (2017) Principles of rehabilitation of older people. Medicine, 45(1), pp. 1-5. (doi: 10.1016/j.mpmed.2016.10.002)
Barber, M., Kendall, M., Cowey, E. , Borthwick, S., Boyd, K., McAlpine, C., Stott, D.J. , Mead, G.E. and Murray, S.A. (2017) Is Palliative Care Appropriate for All People After Major Stroke. 3rd European Stroke Organisation Conference 2017, Prague, Czech Republic, 16-18 May 2017. p. 426. (doi: 10.1177/2396987317705242)
Sachdev, P. S. et al. (2017) STROKOG (stroke and cognition consortium): an international consortium to examine the epidemiology, diagnosis, and treatment of neurocognitive disorders in relation to cerebrovascular disease. Alzheimer's and Dementia, 7, pp. 11-23. (doi: 10.1016/j.dadm.2016.10.006) (PMID:28138511) (PMCID:PMC5257024)
2016
Schumann, G. et al. (2016) KLB is associated with alcohol drinking, and its gene product β-Klotho is necessary for FGF21 regulation of alcohol preference. Proceedings of the National Academy of Sciences of the United States of America, 113(50), pp. 14372-14377. (doi: 10.1073/pnas.1611243113) (PMID:27911795) (PMCID:PMC5167198)
Adams, H. H.H. et al. (2016) Novel genetic loci underlying human intracranial volume identified through genome-wide association. Nature Neuroscience, 19(12), pp. 1569-1582. (doi: 10.1038/nn.4398) (PMID:27694991)
Postmus, I. et al. (2016) Meta-analysis of genome-wide association studies of HDL cholesterol response to statins. Journal of Medical Genetics, 53(12), pp. 835-845. (doi: 10.1136/jmedgenet-2016-103966) (PMID:27587472)
Harrison, J. K. , Stott, D. J. , McShane, R., Noel-Storr, A. H., Swann-Price, R. S. and Quinn, T. J. (2016) Informant questionnaire on cognitive decline in the elderly (IQCODE) for the early diagnosis of dementia across a variety of healthcare settings. Cochrane Database of Systematic Reviews, 2016(11), CD011333. (doi: 10.1002/14651858.cd011333.pub2) (PMID:27869298)
Harrison, J. K. et al. (2016) New horizons: the management of hypertension in people with dementia. Age and Ageing, 45(6), pp. 740-746. (doi: 10.1093/ageing/afw155) (PMID:27836926)
Wijsman, L. W. et al. (2016) High-sensitivity cardiac troponin T is associated with cognitive decline in older adults at high cardiovascular risk. European Journal of Preventive Cardiology, 23(13), pp. 1383-1392. (doi: 10.1177/2047487316632364) (PMID:26884081)
Poortvliet, R. K.E. et al. (2016) Risk stratification and treatment effect of statins in secondary cardiovascular prevention in old age: additive value of N-terminal pro-B-type natriuretic peptide. European Journal of Preventive Cardiology, 23(10), pp. 1104-1113. (doi: 10.1177/2047487315617908) (PMID:26603744)
van Loon, J. et al. (2016) Genome-wide association studies identify genetic loci for low von Willebrand factor levels. European Journal of Human Genetics, 24(7), pp. 1035-1040. (doi: 10.1038/ejhg.2015.222) (PMID:26486471)
Chauhan, G. et al. (2016) Identification of additional risk loci for stroke and small vessel disease: a meta-analysis of genome-wide association studies. Lancet Neurology, 15(7), pp. 695-707. (doi: 10.1016/S1474-4422(16)00102-2) (PMID:27068588) (PMCID:PMC4943223)
Smith, J. G. et al. (2016) Discovery of genetic variation on chromosome 5q22 associated with mortality in heart failure. PLoS Genetics, 12(5), e1006034. (doi: 10.1371/journal.pgen.1006034) (PMID:27149122) (PMCID:PMC4858216)
Blum, M. R. et al. (2016) Subclinical thyroid dysfunction and depressive symptoms among the elderly: a prospective cohort study. Neuroendocrinology, 103(3-4), pp. 291-299. (doi: 10.1159/000437387) (PMID:26202797)
Trompet, S. et al. (2016) Non-response to (statin) therapy: the importance of distinguishing non-responders from non-adherers in pharmacogenetic studies. European Journal of Clinical Pharmacology, 72(4), pp. 431-437. (doi: 10.1007/s00228-015-1994-9) (PMID:26686871)
Ibrahim-Verbaas, C. A. et al. (2016) GWAS for executive function and processing speed suggests involvement of the CADM2 gene. Molecular Psychiatry, 21(2), pp. 189-197. (doi: 10.1038/mp.2015.37) (PMID:25869804) (PMCID:PMC4722802)
de Vries, P. et al. (2016) A meta-analysis of 120 246 individuals identifies 18 new loci for fibrinogen concentration. Human Molecular Genetics, 25(2), pp. 358-370. (doi: 10.1093/hmg/ddv454) (PMID:26561523)
Chaker, L. et al. (2016) Thyroid function within the reference range and the risk of stroke: an individual participant data analysis. Journal of Clinical Endocrinology and Metabolism, 101(11), pp. 4270-4282. (doi: 10.1210/jc.2016-2255) (PMID:27603906)
Hendry, K., Quinn, T. J. , Evans, J. , Scortichini, V., Miller, H., Burns, J., Cunnington, A. and Stott, D. J. (2016) Evaluation of delirium screening tools in geriatric medical inpatients: a diagnostic test accuracy study. Age and Ageing, 45(6), pp. 832-837. (doi: 10.1093/ageing/afw130) (PMID:27503794)
2015
Hofer, E. et al. (2015) White matter lesion progression: genome-wide search for genetic influences. Stroke, 46(11), pp. 3048-3057. (doi: 10.1161/STROKEAHA.115.009252) (PMID:26451028)
Ogliari, G. et al. (2015) Resting heart rate, heart rate variability and functional decline in old age. Canadian Medical Association Journal, 187(15), E442-E449. (doi: 10.1503/cmaj.150462) (PMID:26323697) (PMCID:PMC4610849)
Kato, N. et al. (2015) Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation. Nature Genetics, 47(11), pp. 1282-1293. (doi: 10.1038/ng.3405) (PMID:26390057) (PMCID:PMC4719169)
Nikpay, M. et al. (2015) A comprehensive 1000 Genomes–based genome-wide association meta-analysis of coronary artery disease. Nature Genetics, 47(10), pp. 1121-1130. (doi: 10.1038/ng.3396) (PMID:26343387) (PMCID:PMC4589895)
Brady, M. C. et al. (2015) Clinical and cost effectiveness of enhanced oral healthcare in stroke care settings (SOCLE II): a pilot, stepped wedge, cluster randomized, controlled trial protocol. International Journal of Stroke, 10(6), pp. 979-984. (doi: 10.1111/ijs.12530) (PMID:26079661)
Quinn, T. J. , Alghamdi, J., Padmanabhan, S. , Porteous, D. J., Smith, B. H., Hocking, L., Deary, I. J., Gallacher, J., Messow, M. and Stott, D. J. (2015) Association between cognition and gene polymorphisms involved in thrombosis and haemostasis. Age, 37(4), p. 80. (doi: 10.1007/s11357-015-9820-y) (PMID:26228839) (PMCID:26228839)
Åsvold, B. O. et al. (2015) Thyroid function within the normal range and risk of coronary heart disease. JAMA Internal Medicine, 175(6), pp. 1037-1047. (doi: 10.1001/jamainternmed.2015.0930) (PMID:25893284)
Blum, M. R. et al. (2015) Subclinical thyroid dysfunction and fracture risk. JAMA: Journal of the American Medical Association, 313(20), pp. 2055-2065. (doi: 10.1001/jama.2015.5161) (PMID:26010634) (PMCID:PMC4729304)
Verhaaren, B. F. J. et al. (2015) Multiethnic genome-wide association study of cerebral white matter hyperintensities on MRI. Circulation: Cardiovascular Genetics, 8(2), pp. 398-409. (doi: 10.1161/CIRCGENETICS.114.000858) (PMID:25663218)
Cowey, E. , Smith, L. N., Stott, D. J. , McAlpine, C. H., Mead, G. E., Barber, M. and Walters, M. (2015) Impact of a clinical pathway on end-of-life care following stroke: a mixed methods study. Palliative Medicine, 29(3), pp. 249-259. (doi: 10.1177/0269216314551378) (PMID:25249241)
Hendry, K., Hill, E., Quinn, T. J. , Evans, J. and Stott, D. J. (2015) Single screening questions for cognitive impairment in older people: a systematic review. Age and Ageing, 44(2), pp. 322-326. (doi: 10.1093/ageing/afu167)
Wijsman, L. W., de Craen, A. J.M., Muller, M., Sabayan, B., Stott, D. , Ford, I. , Trompet, S., Jukema, J. W., Westendorp, R. G.J. and Mooijaart, S. P. (2015) Blood pressure lowering medication, visit-to-visit blood pressure variability, and cognitive function in old age. American Journal of Hypertension, 29(3), pp. 311-318. (doi: 10.1093/ajh/hpv101) (PMID:26156873)
Davies, G. et al. (2015) Genetic contributions to variation in general cognitive function: a meta-analysis of genome-wide association studies in the CHARGE consortium (N=53 949). Molecular Psychiatry, 20(2), pp. 183-192. (doi: 10.1038/mp.2014.188) (PMID:25644384) (PMCID:PMC4356746)
den Elzen, W.P. et al. (2015) International variation in GP treatment strategies for subclinical hypothyroidism in older adults: a case-based survey. British Journal of General Practice, 65(631), e121-e132. (doi: 10.3399/bjgp15X683569)
Bis, J. C. et al. (2015) Drug-gene interactions of antihypertensive medications and risk of incident cardiovascular disease: a pharmacogenomics study from the CHARGE consortium. PLoS ONE, 10(10), e0140496. (doi: 10.1371/journal.pone.0140496) (PMID:26516778) (PMCID:PMC4627813)
Chaker, L. et al. (2015) Subclinical hypothyroidism and the risk of stroke events and fatal stroke: an individual participant data analysis. Journal of Clinical Endocrinology and Metabolism, 100(6), pp. 2181-2191. (doi: 10.1210/jc.2015-1438) (PMID:25856213)
Harrison, J. K. , Fearon, P., Noel-Storr, A. H., McShane, R., Stott, D. J. and Quinn, T. J. (2015) Informant questionnaire on cognitive decline in the elderly (IQCODE) for the diagnosis of dementia within a secondary care setting. Cochrane Database of Systematic Reviews, 2015(3), CD010772. (doi: 10.1002/14651858.CD010772.pub2) (PMID:25754745)
Hendry, K., Quinn, T. J. , Evans, J. J. and Stott, D. J. (2015) Informant single screening questions for delirium and dementia in acute care – a cross-sectional test accuracy pilot study. BMC Geriatrics, 15, 17. (doi: 10.1186/s12877-015-0016-1) (PMCID:PMC4345037)
Loeffen, R., Winckers, K., Ford, I. , Jukema, J. W., Robertson, M., Stott, D. J. , Spronk, H. M., ten Cate, H. and Lowe, G. (2015) Associations between thrombin generation and the risk of cardiovascular disease in elderly patients: results from the PROSPER study. Journals of Gerontology Series A: Biological Sciences and Medical Sciences, 70(8), pp. 982-988. (doi: 10.1093/gerona/glu228) (PMID:25540034)
Poortvliet, R. K.E. et al. (2015) Biological correlates of blood pressure variability in elderly at high risk of cardiovascular disease. American Journal of Hypertension, 28(4), pp. 469-479. (doi: 10.1093/ajh/hpu181) (PMID:25298176)
van Leeuwen, E. M. et al. (2015) Genome of the Netherlands population-specific imputations identify an ABCA6 variant associated with cholesterol levels. Nature Communications, 6, 6065. (doi: 10.1038/ncomms7065) (PMID:25751400) (PMCID:PMC4366498)
2014
Welsh, P. et al. (2014) Contrasting associations of insulin resistance with diabetes, cardiovascular disease and all-cause mortality in the elderly: PROSPER long-term follow-up. Diabetologia, 57(12), pp. 2513-2520. (doi: 10.1007/s00125-014-3383-9) (PMID:25264116)
Clarke, R. et al. (2014) Effects of homocysteine lowering with B vitamins on cognitive aging: meta-analysis of 11 trials with cognitive data on 22,000 individuals. American Journal of Clinical Nutrition, 100(2), pp. 657-666. (doi: 10.3945/ajcn.113.076349) (PMID:24965307) (PMCID:PMC4095663)
Wijsman, L. W. et al. (2014) N-terminal pro-brain natriuretic peptide and cognitive decline in older adults at high cardiovascular risk. Annals of Neurology, 76(2), pp. 213-222. (doi: 10.1002/ana.24203)
Postmus, I. et al. (2014) In search for genetic determinants of clinically meaningful differential cardiovascular event reduction by pravastatin in the PHArmacogenetic study of Statins in the Elderly at risk (PHASE)/PROSPER study. Atherosclerosis, 235(1), pp. 58-64. (doi: 10.1016/j.atherosclerosis.2014.04.009)
Lubitz, S.A. et al. (2014) Novel genetic markers associate with atrial fibrillation risk in Europeans and Japanese. Journal of the American College of Cardiology, 63(12), pp. 1200-1210. (doi: 10.1016/j.jacc.2013.12.015)
Virgini, V.S. et al. (2014) Subclinical thyroid dysfunction and functional capacity among elderly. Thyroid, 24(2), pp. 208-214. (doi: 10.1089/thy.2013.0071)
Drewes, Y.M. et al. (2014) Homocysteine levels and treatment effect in the prospective study of pravastatin in the elderly at risk. Journal of the American Geriatrics Society, 62(2), pp. 213-221. (doi: 10.1111/jgs.12660)
Perez, A. C., Jhund, P. S. , Stott, D. J. , Gullestad, L., Cleland, J. G.F. , van Veldhuisen, D. J., Wikstrand, J., Kjekshus, J. and McMurray, J. J.V. (2014) Thyroid-stimulating hormone and clinical outcomes. JACC: Heart Failure, 2(1), pp. 35-40. (doi: 10.1016/j.jchf.2013.07.008)
Avery, C.L. et al. (2014) Drug–gene interactions and the search for missing heritability: a cross-sectional pharmacogenomics study of the QT interval. Pharmacogenomics Journal, 14(1), pp. 6-13. (doi: 10.1038/tpj.2013.4)
Baumert, J. et al. (2014) No evidence for genome-wide interactions on plasma fibrinogen by smoking, alcohol consumption and body mass index: results from meta-analyses of 80,607 subjects. PLoS ONE, 9(12), e111156. (doi: 10.1371/journal.pone.0111156) (PMID:25551457) (PMCID:PMC4281156)
Deelen, J. et al. (2014) Genome-wide association meta-analysis of human longevity identifies a novel locus conferring survival beyond 90 years of age. Human Molecular Genetics, 23(16), pp. 4420-4432. (doi: 10.1093/hmg/ddu139)
Harrison, J. K. , Fearon, P., Noel-Storr, A. H., McShane, R., Stott, D. J. and Quinn, T. J. (2014) Informant Questionnaire on Cognitive Decline in the Elderly (IQCODE) for the diagnosis of dementia within a general practice (primary care) setting. Cochrane Database of Systematic Reviews, 7, CD010771. (doi: 10.1002/14651858.CD010771.pub2)
Hendry, K., Lees, R. A., McShane, R., Noel-Storr, A. H., Stott, D. J. and Quinn, T. J. (2014) AD-8 for diagnosis of dementia across a variety of healthcare settings. Cochrane Database of Systematic Reviews, 5, CD011121. (doi: 10.1002/14651858.CD011121)
Huang, J. et al. (2014) Genome-wide association study for circulating tissue plasminogen activator levels and functional follow-up implicates endothelial STXBP5 and STX2. Arteriosclerosis, Thrombosis, and Vascular Biology, 34(5), pp. 1093-1101. (doi: 10.1161/ATVBAHA.113.302088)
Lees, R., Selvarajah, J., Fenton, C. , Pendlebury, S. T., Langhorne, P. , Stott, D. and Quinn, T. (2014) Test accuracy of cognitive screening tests for diagnosis of dementia and multidomain cognitive impairment in stroke. Stroke, 45(10), pp. 3008-3018. (doi: 10.1161/strokeaha.114.005842)
Lees, R. A., Stott, D. J. , McShane, R., Noel-Storr, A. H. and Quinn, T. J. (2014) Informant Questionnaire on Cognitive Decline in the Elderly (IQCODE) for the early diagnosis of dementia across a variety of healthcare settings. Cochrane Database of Systematic Reviews, 10, CD011333. (doi: 10.1002/14651858.CD011333)
Postmus, I. et al. (2014) Pharmacogenetic meta-analysis of genome-wide association studies of LDL cholesterol response to statins. Nature Communications, 5, (doi: 10.1038/ncomms6068)
Quinn, T. J. , Fearon, P., Noel-Storr, A. H., Young, C., McShane, R. and Stott, D. J. (2014) Informant Questionnaire on Cognitive Decline in the Elderly (IQCODE) for the diagnosis of dementia within community dwelling populations. Cochrane Database of Systematic Reviews, 2014(4), CD010079. (doi: 10.1002/14651858.CD010079.pub2)
Wood, A. R. et al. (2014) Defining the role of common variation in the genomic and biological architecture of adult human height. Nature Genetics, 46(11), pp. 1173-1186. (doi: 10.1038/ng.3097) (PMID:25282103) (PMCID:PMC4250049)
2013
McArthur, K., Beagan, M.L.C., Degnan, A., Howarth, R.C., Mitchell, K.A., McQuaige, F.B., Shannon, M.A.C., Stott, D.J. and Quinn, T.J. (2013) Properties of proxy-derived modified Rankin scale assessment. International Journal of Stroke, 8(6), pp. 403-407. (doi: 10.1111/j.1747-4949.2011.00759.x)
Mooijaart, S.P., Sattar, N. , Trompet, S., Lucke, J., Stott, D.J. , Ford, I. , Jukema, J.W., Westendorp, R.G.J. and de Craen, A.J.M. (2013) Circulating interleukin-6 concentration and cognitive decline in old age: the PROSPER study. Journal of Internal Medicine, 274(1), pp. 77-85. (doi: 10.1111/joim.12052)
Nanchen, D. et al. (2013) Resting heart rate and incident heart failure and cardiovascular mortality in older adults: role of inflammation and endothelial dysfunction: the PROSPER study. European Journal of Heart Failure, 15(5), pp. 581-588. (doi: 10.1093/eurjhf/hfs195)
Handoll, H.H., Stott, D.J. , Elstub, L.J., Elliott, J.C., Kavanagh, A.L. and Madhok, R. (2013) A framework for effective collaboration between specialist and broad-spectrum groups for delivering priority Cochrane reviews. Journal of Clinical Epidemiology, 66(5), pp. 490-495. (doi: 10.1016/j.jclinepi.2012.01.016)
Postmus, I., Trompet, S., de Craen, A.J.M., Buckley, B.M., Ford, I. , Stott, D.J. , Sattar, N. , Slagboom, P.E., Westendorp, R.G.J. and Jukema, J.W. (2013) PCSK9 SNP rs11591147 is associated with low cholesterol levels but not with cognitive performance or noncardiovascular clinical events in an elderly population. Journal of Lipid Research, 54(2), pp. 561-566. (doi: 10.1194/jlr.P033969)
Duffy, L., Gajree, S., Langhorne, P. , Stott, D.J. and Quinn, T.J. (2013) Reliability (inter-rater agreement) of the Barthel index for assessment of stroke survivors: systematic review and meta-analysis. Stroke, 44(2), pp. 462-468. (doi: 10.1161/STROKEAHA.112.678615)
Legg, L., Weir, C.J., Langhorne, P. , Smith, L. and Stott, D.J. (2013) Is informal caregiving independently associated with poor health? A population-based study. Journal of Epidemiology and Community Health, 67(1), pp. 95-97. (doi: 10.1136/jech-2012-201652)
Lloyd, S.M. et al. (2013) Long-term effects of statin treatment in elderly people: Extended follow-up of the PROspective study of Pravastatin in the elderly at risk (PROSPER). PLoS ONE, 8(9), e72642. (doi: 10.1371/journal.pone.0072642) (PMID:24023757) (PMCID:PMC3759378)
McCarthy, M.I. et al. (2013) A meta-analysis of thyroid-related traits reveals novel loci and gender-specific differences in the regulation of thyroid function. PLoS Genetics, 9(2), e1003266. (doi: 10.1371/journal.pgen.1003266)
Sabater-Lleal, M. et al. (2013) Multiethnic meta-analysis of genome-wide association studies in >100 000 subjects identifies 23 fibrinogen-associated loci but no strong evidence of a causal association between circulating fibrinogen and cardiovascular disease. Circulation, 128(12), pp. 1310-1324. (doi: 10.1161/CIRCULATIONAHA.113.002251)
Sabayan, B. et al. (2013) Association of visit-to-visit variability in blood pressure with cognitive function in old age: prospective cohort study. BMJ Open, 347, f4600. (doi: 10.1136/bmj.f4600)
Stott, D.J. , Young, C., Howe, T., Quinn, T.J. and Langhorne, P. (2013) The Cochrane Collaboration and geriatric medicine. Age and Ageing, 42(6), pp. 677-678. (doi: 10.1093/ageing/aft137)
Verschuren, J.J.W. et al. (2013) Non-homologous end-joining pathway associated with occurrence of myocardial infarction: gene set analysis of genome-wide association study data. PLoS ONE, 8(2), e56262. (doi: 10.1371/journal.pone.0056262) (PMID:23457540) (PMCID:PMC3574159)
Wijsman, L.W., de Craen, A.J.M., Trompet, S., Gussekloo, J., Stott, D.J. , Rodondi, N., Welsh, P. , Jukema, J.W., Westendorp, R.G.J. and Mooijaart, S.P. (2013) Subclinical thyroid dysfunction and cognitive decline in old age. PLoS ONE, 8(3), e59199. (doi: 10.1371/journal.pone.0059199) (PMID:23554996) (PMCID:PMC3595244)
2012
Verschuren, J.J.W., Wessels, J.A., Trompet, S., Stott, D.J. , Sattar, N. , Buckley, B., Guchelaar, H.-J. and Jukema, J. (2012) Genetic variation in the SMARCA2 gene is associated with cardiovascular events. Journal of the American College of Cardiology, 59(13), E1393. (doi: 10.1016/S0735-1097(12)61394-1)
Nanchen, D. et al. (2012) Subclinical thyroid dysfunction and the risk of heart failure in older persons at high cardiovascular risk. Journal of Clinical Endocrinology and Metabolism, 97(3), pp. 852-861. (doi: 10.1210/jc.2011-1978)
Harrison, J. K. , Quinn, T. J. and Stott, D. J. (2012) Planning cardiovascular investigations and management of older people. In: Stott, D.J. and Lowe, G.D.O. (eds.) Cardiovascular Disease and Health in the Older Patient. Wiley-Blackwell: Chichester, pp. 376-393. ISBN 9780470973721 (doi: 10.1002/9781118451786.ch16)
Legg, L.A., Quinn, T.J. , Mahmood, F., Weir, C.J., Tierney, J., Stott, D.J. , Smith, L.N. and Langhorne, P. (2012) Nonpharmacological interventions for caregivers of stroke survivors. Stroke, 43(3), e30-e31. (doi: 10.1161/STROKEAHA.111.644914)
Poortvliet, R.K.E. et al. (2012) Blood pressure variability and cardiovascular risk in the PROspective study of pravastatin in the elderly at risk (PROSPER). PLoS ONE, 7(12), e52438. (doi: 10.1371/journal.pone.0052438) (PMID:23285043) (PMCID:PMC3527505)
Quinn, T.J. and Stott, D.J. (2012) Cardiac ageing and systemic disorders. In: Sinclair, A.J., Morley, J.E. and Vellas, B. (eds.) Pathy's Principle and Practice of Geriatric Medicine. Wiley-Blackwell: Chichester, UK, pp. 405-412. ISBN 9780470683934 (doi: 10.1002/9781119952930.ch35)
Shiffman, D. et al. (2012) Genome-wide study of gene variants associated with differential cardiovascular event reduction by Pravastatin therapy. PLoS ONE, 7(5), e38240. (doi: 10.1371/journal.pone.0038240) (PMID:22666496) (PMCID:PMC3364212)
Stott, D.J. et al. (2012) RCPE UK consensus conference on 'Approaching the comprehensive management of atrial fibrillation: evolution or revolution?'. Journal of the Royal College of Physicians of Edinburgh, 42(1), pp. 34-35. (doi: 10.4997/JRCPE.2012.S01)
Stott, D.J. et al. (2012) RCPE UK consensus conference on 'Approaching the comprehensive management of atrial fibrillation: evolution or revolution?'. Journal of the Royal College of Physicians of Edinburgh, 42(Sup 4),
Trompet, S., Jukema, W., Mooijaart, S.P., Ford, I. , Stott, D.J. , Westendorp, R.G.J. and de Craen, A.J.M. (2012) Genetic variation in galectin-3 gene associates with cognitive function at old age. Neurobiology of Aging, 33(9), 2232.e1-2232.e9. (doi: 10.1016/j.neurobiolaging.2012.05.001)
2011
Ford, I. et al. (2011) The inverse relationship between alanine aminotransferase in the normal range and adverse cardiovascular and non-cardiovascular outcomes. International Journal of Epidemiology, 40(6), pp. 1530-1538. (doi: 10.1093/ije/dyr172)
van Es, A.C.G.M. et al. (2011) Cerebral microbleeds and cognitive functioning in the PROSPER study. Neurology, 77(15), pp. 1446-1452. (doi: 10.1212/WNL.0b013e318232ab1d)
Trompet, S. et al. (2011) Replication of LDL SWAs hits in PROSPER/PHASE as validation for future (pharmaco)genetic analyses. BMC Medical Genetics, 12, p. 131. (doi: 10.1186/1471-2350-12-131)
Welsh, P. et al. (2011) Circulating interleukin-10 and risk of cardiovascular events: a prospective study in the elderly at risk. Arteriosclerosis, Thrombosis, and Vascular Biology, 31(10), pp. 2338-2344. (doi: 10.1161/ATVBAHA.111.231795) (PMID:21757655)
Mooijaart, S.P. et al. (2011) C-Reactive protein and genetic variants and cognitive decline in old age: the PROSPER Study. PLoS ONE, 6(9), e23890. (doi: 10.1371/journal.pone.0023890) (PMID:21915265) (PMCID:PMC3168438)
Quinn, T.J. , McArthur, K., Ellis, G. and Stott, D.J. (2011) Functional assessment in older people. British Medical Journal, 343, d4681. (doi: 10.1136/bmj.d4681)
Quinn, T.J. , Gallacher, J., Deary, I.J., Lowe, G.D.O., Fenton, C. and Stott, D.J. (2011) Association between circulating hemostatic measures and dementia or cognitive impairment: systematic review and meta-analyzes. Journal of Thrombosis and Haemostasis, 9(8), pp. 1475-1482. (doi: 10.1111/j.1538-7836.2011.04403.x)
Widya, R. L. et al. (2011) Increased amygdalar and hippocampal volumes in elderly obese individuals with or at risk of cardiovascular disease. American Journal of Clinical Nutrition, 93(6), pp. 1190-1195. (doi: 10.3945/ajcn.110.006304)
Rahimi, K. et al. (2011) Effect of statins on atrial fibrillation: collaborative meta-analysis of published and unpublished evidence from randomised controlled trials. British Medical Journal, 342, d1250. (doi: 10.1136/bmj.d1250)
Stott, D.J. and Handoll, H. (2011) Rehabilitation of older people after hip (proximal femoral) fracture. Cochrane Database of Systematic Reviews, 2011(8), ED000023.
Altmann-Schneider, I., Trompet, S., de Craen, A. J. M., van Es, A. C. G. M., Jukema, J. W., Stott, D.J. , Sattar, N. , Westendorp, R. G. J., van Buchem, M. A. and van der Grond, J. (2011) Cerebral Microbleeds Are Predictive of Mortality in the Elderly. Stroke, 42(3), pp. 638-644. (doi: 10.1161/STROKEAHA.110.595611)
Brady, M.C., Stott, D.J. , Norrie, J., Chalmers, C., St George, B., Sweeney, P.M. and Langhorne, P. (2011) Developing and evaluating the implementation of a complex intervention: using mixed methods to inform the design of a randomised controlled trial of an oral healthcare intervention after stroke. Trials, 12(168), (doi: 10.1186/1745-6215-12-168)
Freeman, D. J. et al. (2011) Incident venous thromboembolic events in the Prospective Study of Pravastatin in the Elderly at Risk (PROSPER). BMC Geriatrics, 11, 8. (doi: 10.1186/1471-2318-11-8) (PMID:21342490) (PMCID:PMC3053238)
Kerr, G.D., Higgins, P., Walters, M. , Ghosh, S.K., Wright, F., Langhorne, P. and Stott, D.J. (2011) Socioeconomic status and transient ischaemic attack / stroke: a prospective observational study. Cerebrovascular Diseases, 31(2), pp. 130-137. (doi: 10.1159/000321732)
Kerr, G.D., Robertson, M. and Stott, D.J. (2011) Long-term follow-up of cognitive function and activities of daily living in older people: a feasibility study in the PROSPER cohort. Open Clinical Trials Journal, 3(1), pp. 6-12. (doi: 10.2174/1876821001103010006)
Kerr, G.D., Slavin, H., Clark, D., Coupar, F., Langhorne, P. and Stott, D.J. (2011) Do vascular risk factors explain the association between socioeconomic status and stroke incidence: a meta-analysis. Cerebrovascular Diseases, 31(1), pp. 57-63. (doi: 10.1159/000320855)
Langhorne, P. and Stott, D. (2011) Letter by Langhorne and Stott Regarding Article, "Very Early Mobilization After Stroke Fast-Tracks Return to Walking: Further Results From the Phase II AVERT Randomized Controlled Trial". Stroke, 42(5), e376. (doi: 10.1161/STROKEAHA.111.613554)
Legg, L.A., Quinn, T.J. , Mahmood, F., Weir, C.J., Tierney, J., Stott, D.J. , Smith, L.N. and Langhorne, P. (2011) Non-pharmacological interventions for caregivers of stroke survivors. Cochrane Database of Systematic Reviews, 10, CD008179. (doi: 10.1002/14651858.CD008179.pub2)
Macfarlane, P.W., Murray, H., Sattar, N. , Stott, D.J. , Ford, I. , Buckley, B., Jukema, J.W., Westendorp, R.G.J. and Shepherd, J. (2011) The incidence and risk factors for new onset atrial fibrillation in the PROSPER study. Europace, 13(5), pp. 634-639. (doi: 10.1093/europace/eur016)
Mutsaerts, H.J.M.M. et al. (2011) Diastolic carotid artery wall shear stress is associated with cerebral infarcts and periventricular white matter lesions. Stroke, 42(12), pp. 3497-3501. (doi: 10.1161/STROKEAHA.111.614453)
Pons, D. et al. (2011) Genetic variation in PCAF, a key mediator in epigenetics, is associated with reduced vascular morbidity and mortality: evidence for a new concept from three independent prospective studies. Heart, 97(2), pp. 143-150. (doi: 10.1136/hrt.2010.199927)
Quinn, T.J. , Langhorne, P. and Stott, D.J. (2011) Barthel index for stroke trials: development, properties, and application. Stroke, 42(4), pp. 1146-1151. (doi: 10.1161/STROKEAHA.110.598540)
Smith, N. L. et al. (2011) Genetic predictors of fibrin D-Dimer levels in healthy adults. Circulation, 123(17), pp. 1864-1872. (doi: 10.1161/CIRCULATIONAHA.110.009480)
Wain, L.V. et al. (2011) Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure. Nature Genetics, 43(10), pp. 1005-1011. (doi: 10.1038/ng.922)
2010
Schofield, I., Stott, D.J. , Tolson, D., McFadyen, A., Monaghan, J. and Nelson, D. (2010) Screening for cognitive impairment in older people attending accident and emergency using the 4-item abbreviated mental test. European Journal of Emergency Medicine, 17(6), pp. 340-342. (doi: 10.1097/MEJ.0b013e32833777ab)
Caslake, M.J. et al. (2010) Lipoprotein-associated phospholipase A2 inflammatory biomarkers, and risk of cardiovascular disease in the Prospective Study of Pravastatin in the Elderly at Risk (PROSPER). Atherosclerosis, 210(1), pp. 28-34. (doi: 10.1016/j.atherosclerosis.2009.10.041)
Sattar, N. et al. (2010) Statins and risk of incident diabetes: a collaborative meta-analysis of randomised statin trials. Lancet, 375(9716), pp. 735-742. (doi: 10.1016/S0140-6736(09)61965-6)
Trompet, S. et al. (2010) Pravastatin and cognitive function in the elderly. Results of the PROSPER study. Journal of Neurology, 257(1), pp. 85-90. (doi: 10.1007/s00415-009-5271-7)
Welsh, P. et al. (2010) Unraveling the directional link between adiposity and inflammation: a bidirectional mendelian randomization approach. Journal of Clinical Endocrinology and Metabolism, 95(1), pp. 93-99. (doi: 10.1210/jc.2009-1064)
Langhorne, P. , Stott, D. , Knight, A., Bernhardt, J., Barer, D. and Watkins, C. (2010) Very Early Rehabilitation or Intensive Telemetry after Stroke: A Pilot Randomised Trial. Cerebrovascular Diseases, 29(4), pp. 352-360. (doi: 10.1159/000278931)
Legg, L.A., Langhorne, P. , Tierney, J., Stott, D.J. , Weir, C. and Smith, L.N. (2010) Non-pharmacological interventions for caregivers of stroke survivors. Cochrane Database of Systematic Reviews, 1, CD008179. (doi: 10.1002/14651858.CD008179)
Stott, D.J. et al. (2010) Activation of Hemostasis and Decline in Cognitive Function in Older People. Arteriosclerosis, Thrombosis, and Vascular Biology, 30(3), pp. 605-611. (doi: 10.1161/ATVBAHA.109.199448)
2009
Mcmurdo, M.E.T., Price, R.J.G., Shields, M., Potter, J. and Stott, D.J. (2009) Should oral nutritional supplementation be given to undernourished older people upon hospital discharge? A controlled trial. Journal of the American Geriatrics Society, 57(12), pp. 2239-2245. (doi: 10.1111/j.1532-5415.2009.02568.x)
Stott, D.J., Welsh, P.I., Rumley, A., Robertson, M., Ford, I. , Sattar, N.A., Westendorp, R.G.J., Jukema, J.W., Cobbe, S. and Lowe, G.D. (2009) Adipocytokines and risk of stroke in older people: a nested case-control study. International Journal of Epidemiology, 38(1), pp. 253-261. (doi: 10.1093/ije/dyn215)
Welsh, P. et al. (2009) Leptin Predicts Diabetes but Not Cardiovascular Disease Results from a large prospective study in an elderly population. Diabetes Care, 32(2), pp. 308-310. (doi: 10.2337/dc08-1458)
Ford, I. et al. (2009) Reduced glomerular filtration rate and its association with clinical outcome in older patients at risk of vascular events: secondary analysis. PLoS Medicine, 6(1), e1000016. (doi: 10.1371/journal.pmed.1000016)
Gordon, A., Hu, H., Byrne, A. and Stott, D.J. (2009) Dementia screening in acute medical and geriatric hospital admissions. Psychiatric Bulletin, 33(2), pp. 52-54. (doi: 10.1192/pb.bp.107.016550)
Kerr, G., Ray, G., Stott, D., Wu, O. and Langhorne, P. (2009) Elevated Troponin after Stroke: A Systematic Review. Cerebrovascular Diseases, 28(3), pp. 220-226. (doi: 10.1159/000226773)
Kerr, G., Sellars, C., Bowie, L., Bagg, J., Sweeney, M., Langhorne, P. and Stott, D.J. (2009) Xerostomia after acute stroke. Cerebrovascular Diseases, 28(6), pp. 624-626. (doi: 10.1159/000253147)
Sattar, N.A. et al. (2009) Are markers of inflammation more strongly associated with risk for fatal than for nonfatal vascular events? PLoS Medicine, 6(6), e1000099. (doi: 10.1371/journal.pmed.1000099)
Sattar, N. et al. (2009) Are elevated circulating intercellular adhesion molecule 1 levels more strongly predictive of diabetes than vascular risk? Outcome of a prospective study in the elderly. Diabetologia, 52(2), pp. 235-239.
Stott, D.J., Falconer, A., Miller, H., Tilston, J.C. and Langhorne, P. (2009) Urinary tract infection after stroke. QJM: An International Journal of Medicine, 102(4), pp. 243-249. (doi: 10.1093/qjmed/hcp012)
Trompet, S., de Craen, A.J.M., Mooijaart, S., Stott, D.J. , Ford, I. , Sattar, N.A. , Jukema, W. and Westendorp, R.G.J. (2009) High innate production capacity of proinflammatory cytokines increases risk for death from cancer: results of the PROSPER study. Clinical Cancer Research, 15(24), pp. 7744-7748. (doi: 10.1158/1078-0432.CCR-09-2152)
Welsh, P., Barber, M., Langhorne, P., Rumley, A., Lowe, G. and Stott, D. (2009) Associations of Inflammatory and Haemostatic Biomarkers with Poor Outcome in Acute Ischaemic Stroke. Cerebrovascular Diseases, 27(3), pp. 247-253. (doi: 10.1159/000196823)
2008
Sattar, N. et al. (2008) Can metabolic syndrome usefully predict cardiovascular disease and diabetes? Outcome data from two prospective studies. Lancet, 371(9628), pp. 1927-1935. (doi: 10.1016/S0140-6736(08)60602-9)
Braid, V., Barber, M., Mitchell, S., Martin, B., Granat, M. and Stott, D. (2008) Randomised controlled trial of electrical stimulation of the quadriceps after proximal femoral fracture. Aging Clinical and Experimental Research, 20(1), pp. 62-66.
Knussen, C., Tolson, D., Brogan, C., Swan, I., Stott, D. and Sullivan, F. (2008) Family caregivers of older relatives: ways of coping and change in distress. Psychology, Health and Medicine, 13(3), pp. 274-290. (doi: 10.1080/13548500701405483)
Stott, D., Falconer, A., Kerr, G., Murray, H., Trompet, S., Westendorp, R., Buckley, B., De Craen, A., Sattar, N. and Ford, I. (2008) Does Low to Moderate Alcohol Intake Protect Against Cognitive Decline in Older People? Journal of the American Geriatrics Society, 56(12), pp. 2217-2224. (doi: 10.1111/j.1532-5415.2008.02007.x)
Stott, D., Langhorne, P. and Knight, P. (2008) Multidisciplinary care for elderly people in the community. Lancet, 371(9614), pp. 699-700. (doi: 10.1016/S0140-6736(08)60317-7)
Trompet, S. et al. (2008) Lymphotoxin-alpha C804A polymorphism is a risk factor for stroke. The PROSPER study. Experimental Gerontology, 43(8), pp. 801-805. (doi: 10.1016/j.exger.2008.04.006)
Trompet, S. et al. (2008) Genetic variation in the interleukin-1 beta-converting enzyme associates with cognitive function. The PROSPER study. Brain, 131(4), pp. 1069-1077. (doi: 10.1093/brain/awn023)
2007
Packard, C.J. et al. (2007) Association between apolipoprotein E4 and cognitive decline in elderly adults. Journal of the American Geriatrics Society, 55(11), pp. 1777-1785. (doi: 10.1111/j.1532-5415.2007.01415.x)
Barber, M., Barlow, N., Macfarlane, P., Morton, J., Roditi, G. and Stott, D. (2007) Elevated troponin levels are associated with sympathoadrenal activation in acute ischaemic stroke. Cerebrovascular Diseases, 23, pp. 260-266. (doi: 10.1159/000098325)
Barber, M., Langhorne, P., Stott, D. and Wright, F. (2007) Early neurological deterioration in acute stroke. QJM: An International Journal of Medicine, 100(1), p. 62.
Langhorne, P., Stott, D. and Wright, F. (2007) Improved survival after stroke. Cerebrovascular Diseases, 23(4), pp. 320-321.
Legg, L., Stott, D. , Ellis, G. and Sellars, C. (2007) Volunteer Stroke Service (VSS) groups for patients with communication difficulties after stroke: a qualitative analysis of the value of groups to their users. Clinical Rehabilitation, 21(9), pp. 794-804.
McCormick, L. and Stott, D. (2007) Anaemia in elderly patients. Clinical Medicine, 7(5), pp. 501-504.
Sattar, N. et al. (2007) C-reactive protein and prediction of coronary heart disease and global vascular events in the prospective study of pravastatin in the elderly at risk (PROSPER). Circulation, 115(8), pp. 981-989. (doi: 10.1161/CIRCULATIONAHA.106.643114)
Sellars, C., Bowie, L., Bagg, J. , Sweeney, M.P., Miller, H., Tilston, J., Langhorne, P. and Stott, D.J. (2007) Risk factors for chest infection in acute stroke: a prospective cohort study. Stroke, 38(8), pp. 2284-2291. (doi: 10.1161/STROKEAHA.106.478156)
Trompet, S. et al. (2007) Genetic variation in the interleukin-10 gene promoter and risk of coronary and cerebrovascular events - The PROSPER study. In: Rattan, S. and Akman, S. (eds.) Biogerontology: Mechanisms and Interventions. Series: Annals of the New York Academy of Sciences (1100). Blackwell Publishing: Oxford, pp. 189-198. ISBN 978-1-57331-679-8 (doi: 10.1196/annals.1395.018)
2006
Barber, M., Langhorne, P. , Rumley, A., Lowe, G.D.O. and Stott, D.J. (2006) D-dimer predicts early clinical progression in ischemic stroke: confirmation using routine clinical assays. Stroke, 37(4), pp. 1113-1115. (doi: 10.1161/01.STR.0000209240.63821.1a)
Agnew, R., Bowman, A., Burrow, K., Buttery, A., Knight, P., Mitchell, S., Ramsay, S. and Stott, D. (2006) Comprehensive geriatric assessment and home-based rehabilitation for elderly people with a history of recurrent non-elective hospital admissions. Age and Ageing, 35(5), pp. 487-491.
de Craen, A., Stott, D. and Westendorp, R. (2006) Homocysteine, B vitamins, and cardiovascular disease. New England Journal of Medicine, 355(2), pp. 205-206.
Gordon, M. et al. (2006) A means to an endpoint. Good Clinical Practice Journal, 13(10), pp. 25-29.
Stott, D. (2006) Blood pressure in very elderly people. Journal of Hypertension, 24(2), pp. 263-264.
Stott, D. (2006) Cognitive decline in ageing. Asian Journal of Gerontology and Geriatrics, 1(1), pp. 21-25.
2005
Stott, D. J. et al. (2005) Randomized controlled trial of homocysteine-lowering vitamin treatment in elderly patients with vascular disease. American Journal of Clinical Nutrition, 82(6), pp. 1320-1326. (doi: 10.1093/ajcn/82.6.1320) (PMID:16332666)
Knussen, C., Tolson, D., Swan, I., Stott, D. , Brogan, C. and Sullivan, F. (2005) The social and psychological impact of an older relative's hearing difficulties: factors associated with change. Psychology, Health and Medicine, 10(1), pp. 57-63. (doi: 10.1080/13548500512331315361)
Barber, M., Lowe, G., Rumley, A., Scott, J., Stott, D. and Tait, R. (2005) Dementia in subjects with atrial fibrillation; haemostatic function and the role of anticoagulation (vol 33, pg 10, 2004). Age and Ageing, 34,
de Craen, A., Frolich, M., Gussekloo, J., Jolles, J., Mooijaart, S., Stott, D. and Westendorp, R. (2005) Homocysteine, vitamin B-12, and folic acid and the risk of cognitive decline in old age: the Leiden 85-Plus Study. American Journal of Clinical Nutrition, 82, pp. 866-871.
Kamper, A., Stott, D. , Hyland, M., Murray, H. and Ford, I. (2005) Predictors of functional decline in elderly people with vascular risk factors or disease. Age and Ageing, 34, pp. 450-455. (doi: 10.1093/ageing/afi137)
Knussen, C., Tolson, D., Swan, I., Stott, D. and Brogan, C. (2005) Stress proliferation in caregivers: The relationships between caregiving stressors and deterioration in family relationships. Psychology and Health, 20, pp. 207-221. (doi: 10.1080/08870440512331334013)
Packard, C.J. et al. (2005) Plasma lipoproteins and apolipoproteins as predictors of cardiovascular risk and treatment benefit in the PROspective Study of Pravastatin in the Elderly at Risk (PROSPER). Circulation, 112, pp. 3058-3065. (doi: 10.1161/CIRCULATIONAHA.105.526848)
2004
Barber, M., Tait, R.C. , Scott, J., Rumley, A., Lowe, G. and Stott, D.J. (2004) Dementia in subjects with atrial fibrillation: hemostatic function and the role of anticoagulation. Journal of Thrombosis and Haemostasis, 2(11), pp. 1873-1878. (doi: 10.1111/j.1538-7836.2004.00993.x) (PMID:15550013)
Knussen, C., Tolson, D., Swan, I.R.C., Stott, D.J. , Brogan, C.A. and Sullivan, F. (2004) The social and psychological impact of an older relative's hearing difficulties. Psychology, Health and Medicine, 9(1), pp. 3-15. (doi: 10.1080/13548500310001637715)
Barber, M., Fail, M., Langhorne, P., Shields, M. and Stott, D. (2004) Validity and reliability of estimating the Scandinavian Stroke Scale score from medical records. Cerebrovascular Diseases, 17(02-Mar), pp. 224-227.
Barber, M., Langhorne, P., Roditi, G. and Stott, D. (2004) Poor outcome in primary intracerebral haemorrhage: results of a matched comparison. Postgraduate Medical Journal, 80(940), pp. 89-92.
Barber, M., Langhorne, P. and Stott, D. (2004) Barriers to delivery of thrombolysis for acute stroke. Age and Ageing, 33(2), pp. 94-95.
Barber, M., Langhorne, P. and Stott, D. (2004) An internationally agreed definition of progressing stroke. Cerebrovascular Diseases, 18(3), pp. 255-256.
Barber, M., Langhorne, P., Stott, D. and Wright, F. (2004) Predictors of early neurological deterioration after ischaemic stroke: A case-control study. Gerontology, 50(2), pp. 102-109.
Barber, M. and Stott, D. (2004) Validity of the Telephone Interview for Cognitive Status (TICS) in post-stroke subjects. International Journal of Geriatric Psychiatry, 19(1), pp. 75-79.
Barber, M., Langhorne, P. , Rumley, A., Lowe, G.D.O. and Stott, D.J. (2004) Hemostatic function and progressing ischemic stroke: D-dimer predicts early clinical progression. Stroke, 35(6), pp. 1421-1425. (doi: 10.1161/01.STR.0000126890.63512.41)
Chouliara, Z., Kearney, N., Stott, D. , Molassiotis, A. and Miller, M. (2004) Perceptions of older people with cancer of information, decision making and treatment: a systematic review of selected literature. Annals of Oncology, 15(11), pp. 1596-1602.
Chouliara, Z., Kearney, N., Worth, A. and Stott, D. (2004) Challenges in conducting research with hospitalized older people with cancer: drawing from the experience of an ongoing interview-based project. European Journal of Cancer Care, 13, pp. 409-415.
Chouliara, Z., Miller, M., Stott, D. , Molassiotis, A., Twelves, C. and Kearney, N. (2004) Older people with cancer: perceptions and feelings about information, decision-making and treatment--a pilot study. European Journal of Oncology Nursing, 8(3), pp. 257-261. (doi: 10.1016/j.ejon.2003.12.010)
Das, K., Fail, M., Gibb, A., Hill, A., Kane, C., Moylan, T., Stott, D. , Toye, D. and Wolstencroft, K. (2004) Assessment of cognitive function on older hospital inpatients: is the Telephone Interview for Cognitive Status (TICS-M) a useful alternative to the Mini Mental State Examination? International Journal of Geriatric Psychiatry, 19(10), pp. 1008-1009.
2003
Adler, B. and Stott, D. (2003) How far to investigate older people? Clinical Medicine, 3(5), pp. 418-422.
Adler, B. and Stott, D. (2003) Investigating older people - In response. Clinical Medicine, 3(6), pp. 592-593.
Barber, M., Braid, V., Camacho-Hubner, C., Gilmore, D., Grant, S., Jenkins, P. and Stott, D. (2003) IGF-I levels, leg extensor power and physical performance after proximal femoral fracture. Age and Ageing, 32(6), pp. 678-680.
Cameron, M., Granat, M., Pandyan, A., Powell, J. and Stott, D. (2003) Contractures in the post-stroke wrist: a pilot study of its time course of development and its association with upper limb recovery. Clinical Rehabilitation, 17, pp. 88-95. (doi: 10.1191/0269215503cr587oa)
Fraser, N., Rowley, G., Field, M. and Stott, D. (2003) The V-H gene repertoire of splenic B cells and somatic hypermutation in systemic lupus erythematosus. Arthritis Research and Therapy, 5, R114-R121. (doi: 10.1186/ar627)
2002
Barber, M., Braid, V., Granat, M., Grant, S., Martin, B., Mitchell, S. and Stott, D. (2002) Electrical stimulation of quadriceps during rehabilitation following proximal femoral fracture. International Journal of Rehabilitation Research, 25(1), pp. 61-63.
Ford, I. et al. (2002) A prospective study of pravastatin in the elderly at risk (PROSPER): Screening experience and baseline characteristics. Current Controlled Trials in Cardiovascular Medicine, 3, p. 8. (doi: 10.1186/1468-6708-3-8)
Houx, P.J. et al. (2002) Testing cognitive function in elderly populations: the PROSPER study. Journal of Neurology, Neurosurgery and Psychiatry, 73(4), pp. 385-389. (doi: 10.1136/jnnp.73.4.385)
Shepherd, J. et al. (2002) Pravastatin in elderly individuals at risk of vascular disease (PROSPER): a randomised controlled trial. Lancet, 360(9346), pp. 1623-1630. (doi: 10.1016/S0140-6736(02)11600-X)
Stott, D.J. , Kerr, G. and Carman, W.F. (2002) Nosocomial transmission of influenza. Occupational Medicine, 52(5), pp. 249-253. (doi: 10.1093/occmed/52.5.249)
Stott, D. and Taylor, J. (2002) Chronic heart failure and cognitive impairment: co-existence of conditions or true association? European Journal of Heart Failure, 4(1), pp. 7-9.
2001
Barber, M. and Stott, D. (2001) Systematic reviews. Age and Ageing, 30(2), pp. 127-128. (doi: 10.1093/ageing/30.2.127)
Carman, W., Elder, A. and Stott, D. (2001) Influenza in old age. Age and Ageing, 30(5), pp. 361-363.
Grant, S., Martin, B., Mitchell, S. and Stott, D. (2001) Randomized controlled trial of quadriceps training after proximal femoral fracture. Clinical Rehabilitation, 15, pp. 282-290.
Stone, S., Kibbler, C., Bowman, C. and Stott, D. (2001) Controlling infection in British nursing homes - It is time for a national strategy. British Medical Journal, 322(7285), p. 506.
Stott, D.J. , Spilg, E., Campbell, A.M., Rumley, A., Mansoor, M.A. and Lowe, G.D.O. (2001) Haemostasis in ischaemic stroke and vascular dementia. Blood Coagulation and Fibrinolysis, 12(8), pp. 651-657.
2000
Bowman, A. and Stott, D. (2000) Blood pressure and aging. Journal of Human Hypertension, 14(12), pp. 771-772.
Articles
de Vries, P. S. et al. (2024) A genetic association study of circulating coagulation Factor VIII and von Willebrand Factor levels. Blood, (doi: 10.1182/blood.2023021452) (PMID:38320121) (Early Online Publication)
Sterenborg, R. B. T. M. et al. (2024) Multi-trait analysis characterizes the genetics of thyroid function and identifies causal associations with clinical implications. Nature Communications, 15, 888. (doi: 10.1038/s41467-024-44701-9) (PMID:38291025) (PMCID:PMC10828500)
Zonneveld, M. H., Noordam, R., Sabayan, B., Stott, D. J. , Mooijaart, S. P., Blauw, G. J., Jukema, J. W., Sattar, N. and Trompet, S. (2023) Weight loss, visit-to-visit body weight variability and cognitive function in older individuals. Age and Ageing, 52(1), afac312. (doi: 10.1093/ageing/afac312) (PMID:36626325)
Lahti, J. et al. (2022) Genome-wide meta-analyses reveal novel loci for verbal short-term memory and learning. Molecular Psychiatry, 27(11), pp. 4419-4431. (doi: 10.1038/s41380-022-01710-8) (PMID:35974141) (PMCID:PMC9734053)
Du Puy, R. S. et al. (2022) No effect of levothyroxine on hemoglobin in older adults with subclinical hypothyroidism: pooled results from 2 randomized controlled trials. Journal of Clinical Endocrinology and Metabolism, 107(6), e2339-e2347. (doi: 10.1210/clinem/dgac106) (PMID:35218666)
Taylor-Rowan, M. , McGuire, L. , Hafdi, M., Evans, J. , Stott, D. J. , Wetherall, K., Elliott, E., Drozdowska, B. and Quinn, T. J. (2022) Comparative validity of informant tools for assessing pre-stroke cognitive impairment. International Journal of Geriatric Psychiatry, 37(4), pp. 1-10. (doi: 10.1002/gps.5700) (PMID:35278006)
Hasemann, W. et al. (2021) Comparing performance on the months of the year backwards test in hospitalised patients with delirium, dementia and no cognitive impairment: an exploratory study. European Geriatric Medicine, 12(6), pp. 1257-1265. (doi: 10.1007/s41999-021-00521-4) (PMID:34156656)
Lumbers, R. T. et al. (2021) The genomics of heart failure: design and rationale of the HERMES consortium. ESC Heart Failure, 8(6), pp. 5531-5541. (doi: 10.1002/ehf2.13517) (PMID:34480422) (PMCID:PMC8712846)
Schunk, S. J. et al. (2021) Genetically determined NLRP3 inflammasome activation associates with systemic inflammation and cardiovascular mortality. European Heart Journal, 42(18), pp. 1742-1756. (doi: 10.1093/eurheartj/ehab107) (PMID:33748830)
Sargurupremraj, M. et al. (2020) Cerebral small vessel disease genomics and its implications across the lifespan. Nature Communications, 11, 6285. (doi: 10.1038/s41467-020-19111-2) (PMID:33293549) (PMCID:PMC7722866)
Stuber, M. J. et al. (2020) Effect of thyroid hormone therapy on fatigability in older adults with subclinical hypothyroidism: a nested study within a randomized placebo-controlled trial. Journals of Gerontology Series A: Biological Sciences and Medical Sciences, 75(9), e89-e94. (doi: 10.1093/gerona/glaa123) (PMID:32577745) (PMCID:PMC7494024)
Gencer, B. et al. (2020) The impact of Levothyroxine on cardiac function in older adults with Mild subclinical hypothyroidism: a randomized clinical trial. American Journal of Medicine, 133(7), 848-856.e5. (doi: 10.1016/j.amjmed.2020.01.018) (PMID:32171774)
de Montmollin, M. et al. (2020) L-thyroxine therapy for older adults with subclinical hypothyroidism and hypothyroid symptoms: secondary analysis of a randomized trial. Annals of Internal Medicine, 172(11), pp. 709-716. (doi: 10.7326/M19-3193) (PMID:32365355)
Burton, J. K. , Yates, L. C., Whyte, L., Fitzsimmons, E. and Stott J, D. (2020) New horizons in iron deficiency anaemia in older adults. Age and Ageing, 49(3), pp. 309-318. (doi: 10.1093/ageing/afz199)
Zijlstra, L. E., Trompet, S., Mooijaart, S. P., van Buren, M., Sattar, N. , Stott, D. J. and Jukema, J. W. (2020) The association of kidney function and cognitive decline in older patients at risk of cardiovascular disease: a longitudinal data analysis. BMC Nephrology, 21, 81. (doi: 10.1186/s12882-020-01745-5) (PMID:32138689) (PMCID:PMC7059260)
Baylan, S. et al. (2020) Measuring the Effects of Listening for Leisure on Outcome after stroke (MELLO): a pilot randomised controlled trial of mindful music listening. International Journal of Stroke, 15(2), pp. 149-158. (doi: 10.1177/1747493019841250) (PMID:30940047) (PMCID:PMC7045280)
Tieges, Z. et al. (2020) A smartphone-based test for the assessment of attention deficits in delirium: a case-control diagnostic test accuracy study in older hospitalised patients. PLoS ONE, 15(1), e0227471. (doi: 10.1371/journal.pone.0227471) (PMID:31978127) (PMCID:PMC6980392)
Zijlstra, L.E., van Velzen, D.M., Simsek, S., Mooijaart, S.P., van Buren, M., Stott J, D.J. , Ford, I. , Jukema, J. and Trompet, S. (2020) The kidney, subclinical thyroid disease and cardiovascular outcomes in older patients. Endocrine Connections, 9(1), pp. 55-62. (doi: 10.1530/EC-19-0502) (PMID:31846431) (PMCID:PMC6993270)
de las Fuentes, L. et al. (2019) Genome-wide meta-analysis of variant-by-diuretic interactions as modulators of lipid traits in persons of European and African ancestry. Pharmacogenomics Journal, 20(3), pp. 482-493. (doi: 10.1038/s41397-019-0132-y) (PMID:31806883) (PMCID:PMC7260079)
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Harrison, J. K. , Fearon, P., Noel-Storr, A. H., McShane, R., Stott, D. J. and Quinn, T. J. (2015) Informant questionnaire on cognitive decline in the elderly (IQCODE) for the diagnosis of dementia within a secondary care setting. Cochrane Database of Systematic Reviews, 2015(3), CD010772. (doi: 10.1002/14651858.CD010772.pub2) (PMID:25754745)
Hendry, K., Quinn, T. J. , Evans, J. J. and Stott, D. J. (2015) Informant single screening questions for delirium and dementia in acute care – a cross-sectional test accuracy pilot study. BMC Geriatrics, 15, 17. (doi: 10.1186/s12877-015-0016-1) (PMCID:PMC4345037)
Loeffen, R., Winckers, K., Ford, I. , Jukema, J. W., Robertson, M., Stott, D. J. , Spronk, H. M., ten Cate, H. and Lowe, G. (2015) Associations between thrombin generation and the risk of cardiovascular disease in elderly patients: results from the PROSPER study. Journals of Gerontology Series A: Biological Sciences and Medical Sciences, 70(8), pp. 982-988. (doi: 10.1093/gerona/glu228) (PMID:25540034)
Poortvliet, R. K.E. et al. (2015) Biological correlates of blood pressure variability in elderly at high risk of cardiovascular disease. American Journal of Hypertension, 28(4), pp. 469-479. (doi: 10.1093/ajh/hpu181) (PMID:25298176)
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Welsh, P. et al. (2014) Contrasting associations of insulin resistance with diabetes, cardiovascular disease and all-cause mortality in the elderly: PROSPER long-term follow-up. Diabetologia, 57(12), pp. 2513-2520. (doi: 10.1007/s00125-014-3383-9) (PMID:25264116)
Clarke, R. et al. (2014) Effects of homocysteine lowering with B vitamins on cognitive aging: meta-analysis of 11 trials with cognitive data on 22,000 individuals. American Journal of Clinical Nutrition, 100(2), pp. 657-666. (doi: 10.3945/ajcn.113.076349) (PMID:24965307) (PMCID:PMC4095663)
Wijsman, L. W. et al. (2014) N-terminal pro-brain natriuretic peptide and cognitive decline in older adults at high cardiovascular risk. Annals of Neurology, 76(2), pp. 213-222. (doi: 10.1002/ana.24203)
Postmus, I. et al. (2014) In search for genetic determinants of clinically meaningful differential cardiovascular event reduction by pravastatin in the PHArmacogenetic study of Statins in the Elderly at risk (PHASE)/PROSPER study. Atherosclerosis, 235(1), pp. 58-64. (doi: 10.1016/j.atherosclerosis.2014.04.009)
Lubitz, S.A. et al. (2014) Novel genetic markers associate with atrial fibrillation risk in Europeans and Japanese. Journal of the American College of Cardiology, 63(12), pp. 1200-1210. (doi: 10.1016/j.jacc.2013.12.015)
Virgini, V.S. et al. (2014) Subclinical thyroid dysfunction and functional capacity among elderly. Thyroid, 24(2), pp. 208-214. (doi: 10.1089/thy.2013.0071)
Drewes, Y.M. et al. (2014) Homocysteine levels and treatment effect in the prospective study of pravastatin in the elderly at risk. Journal of the American Geriatrics Society, 62(2), pp. 213-221. (doi: 10.1111/jgs.12660)
Perez, A. C., Jhund, P. S. , Stott, D. J. , Gullestad, L., Cleland, J. G.F. , van Veldhuisen, D. J., Wikstrand, J., Kjekshus, J. and McMurray, J. J.V. (2014) Thyroid-stimulating hormone and clinical outcomes. JACC: Heart Failure, 2(1), pp. 35-40. (doi: 10.1016/j.jchf.2013.07.008)
Avery, C.L. et al. (2014) Drug–gene interactions and the search for missing heritability: a cross-sectional pharmacogenomics study of the QT interval. Pharmacogenomics Journal, 14(1), pp. 6-13. (doi: 10.1038/tpj.2013.4)
Baumert, J. et al. (2014) No evidence for genome-wide interactions on plasma fibrinogen by smoking, alcohol consumption and body mass index: results from meta-analyses of 80,607 subjects. PLoS ONE, 9(12), e111156. (doi: 10.1371/journal.pone.0111156) (PMID:25551457) (PMCID:PMC4281156)
Deelen, J. et al. (2014) Genome-wide association meta-analysis of human longevity identifies a novel locus conferring survival beyond 90 years of age. Human Molecular Genetics, 23(16), pp. 4420-4432. (doi: 10.1093/hmg/ddu139)
Harrison, J. K. , Fearon, P., Noel-Storr, A. H., McShane, R., Stott, D. J. and Quinn, T. J. (2014) Informant Questionnaire on Cognitive Decline in the Elderly (IQCODE) for the diagnosis of dementia within a general practice (primary care) setting. Cochrane Database of Systematic Reviews, 7, CD010771. (doi: 10.1002/14651858.CD010771.pub2)
Hendry, K., Lees, R. A., McShane, R., Noel-Storr, A. H., Stott, D. J. and Quinn, T. J. (2014) AD-8 for diagnosis of dementia across a variety of healthcare settings. Cochrane Database of Systematic Reviews, 5, CD011121. (doi: 10.1002/14651858.CD011121)
Huang, J. et al. (2014) Genome-wide association study for circulating tissue plasminogen activator levels and functional follow-up implicates endothelial STXBP5 and STX2. Arteriosclerosis, Thrombosis, and Vascular Biology, 34(5), pp. 1093-1101. (doi: 10.1161/ATVBAHA.113.302088)
Lees, R., Selvarajah, J., Fenton, C. , Pendlebury, S. T., Langhorne, P. , Stott, D. and Quinn, T. (2014) Test accuracy of cognitive screening tests for diagnosis of dementia and multidomain cognitive impairment in stroke. Stroke, 45(10), pp. 3008-3018. (doi: 10.1161/strokeaha.114.005842)
Lees, R. A., Stott, D. J. , McShane, R., Noel-Storr, A. H. and Quinn, T. J. (2014) Informant Questionnaire on Cognitive Decline in the Elderly (IQCODE) for the early diagnosis of dementia across a variety of healthcare settings. Cochrane Database of Systematic Reviews, 10, CD011333. (doi: 10.1002/14651858.CD011333)
Postmus, I. et al. (2014) Pharmacogenetic meta-analysis of genome-wide association studies of LDL cholesterol response to statins. Nature Communications, 5, (doi: 10.1038/ncomms6068)
Quinn, T. J. , Fearon, P., Noel-Storr, A. H., Young, C., McShane, R. and Stott, D. J. (2014) Informant Questionnaire on Cognitive Decline in the Elderly (IQCODE) for the diagnosis of dementia within community dwelling populations. Cochrane Database of Systematic Reviews, 2014(4), CD010079. (doi: 10.1002/14651858.CD010079.pub2)
Wood, A. R. et al. (2014) Defining the role of common variation in the genomic and biological architecture of adult human height. Nature Genetics, 46(11), pp. 1173-1186. (doi: 10.1038/ng.3097) (PMID:25282103) (PMCID:PMC4250049)
McArthur, K., Beagan, M.L.C., Degnan, A., Howarth, R.C., Mitchell, K.A., McQuaige, F.B., Shannon, M.A.C., Stott, D.J. and Quinn, T.J. (2013) Properties of proxy-derived modified Rankin scale assessment. International Journal of Stroke, 8(6), pp. 403-407. (doi: 10.1111/j.1747-4949.2011.00759.x)
Mooijaart, S.P., Sattar, N. , Trompet, S., Lucke, J., Stott, D.J. , Ford, I. , Jukema, J.W., Westendorp, R.G.J. and de Craen, A.J.M. (2013) Circulating interleukin-6 concentration and cognitive decline in old age: the PROSPER study. Journal of Internal Medicine, 274(1), pp. 77-85. (doi: 10.1111/joim.12052)
Nanchen, D. et al. (2013) Resting heart rate and incident heart failure and cardiovascular mortality in older adults: role of inflammation and endothelial dysfunction: the PROSPER study. European Journal of Heart Failure, 15(5), pp. 581-588. (doi: 10.1093/eurjhf/hfs195)
Handoll, H.H., Stott, D.J. , Elstub, L.J., Elliott, J.C., Kavanagh, A.L. and Madhok, R. (2013) A framework for effective collaboration between specialist and broad-spectrum groups for delivering priority Cochrane reviews. Journal of Clinical Epidemiology, 66(5), pp. 490-495. (doi: 10.1016/j.jclinepi.2012.01.016)
Postmus, I., Trompet, S., de Craen, A.J.M., Buckley, B.M., Ford, I. , Stott, D.J. , Sattar, N. , Slagboom, P.E., Westendorp, R.G.J. and Jukema, J.W. (2013) PCSK9 SNP rs11591147 is associated with low cholesterol levels but not with cognitive performance or noncardiovascular clinical events in an elderly population. Journal of Lipid Research, 54(2), pp. 561-566. (doi: 10.1194/jlr.P033969)
Duffy, L., Gajree, S., Langhorne, P. , Stott, D.J. and Quinn, T.J. (2013) Reliability (inter-rater agreement) of the Barthel index for assessment of stroke survivors: systematic review and meta-analysis. Stroke, 44(2), pp. 462-468. (doi: 10.1161/STROKEAHA.112.678615)
Legg, L., Weir, C.J., Langhorne, P. , Smith, L. and Stott, D.J. (2013) Is informal caregiving independently associated with poor health? A population-based study. Journal of Epidemiology and Community Health, 67(1), pp. 95-97. (doi: 10.1136/jech-2012-201652)
Lloyd, S.M. et al. (2013) Long-term effects of statin treatment in elderly people: Extended follow-up of the PROspective study of Pravastatin in the elderly at risk (PROSPER). PLoS ONE, 8(9), e72642. (doi: 10.1371/journal.pone.0072642) (PMID:24023757) (PMCID:PMC3759378)
McCarthy, M.I. et al. (2013) A meta-analysis of thyroid-related traits reveals novel loci and gender-specific differences in the regulation of thyroid function. PLoS Genetics, 9(2), e1003266. (doi: 10.1371/journal.pgen.1003266)
Sabater-Lleal, M. et al. (2013) Multiethnic meta-analysis of genome-wide association studies in >100 000 subjects identifies 23 fibrinogen-associated loci but no strong evidence of a causal association between circulating fibrinogen and cardiovascular disease. Circulation, 128(12), pp. 1310-1324. (doi: 10.1161/CIRCULATIONAHA.113.002251)
Sabayan, B. et al. (2013) Association of visit-to-visit variability in blood pressure with cognitive function in old age: prospective cohort study. BMJ Open, 347, f4600. (doi: 10.1136/bmj.f4600)
Stott, D.J. , Young, C., Howe, T., Quinn, T.J. and Langhorne, P. (2013) The Cochrane Collaboration and geriatric medicine. Age and Ageing, 42(6), pp. 677-678. (doi: 10.1093/ageing/aft137)
Verschuren, J.J.W. et al. (2013) Non-homologous end-joining pathway associated with occurrence of myocardial infarction: gene set analysis of genome-wide association study data. PLoS ONE, 8(2), e56262. (doi: 10.1371/journal.pone.0056262) (PMID:23457540) (PMCID:PMC3574159)
Wijsman, L.W., de Craen, A.J.M., Trompet, S., Gussekloo, J., Stott, D.J. , Rodondi, N., Welsh, P. , Jukema, J.W., Westendorp, R.G.J. and Mooijaart, S.P. (2013) Subclinical thyroid dysfunction and cognitive decline in old age. PLoS ONE, 8(3), e59199. (doi: 10.1371/journal.pone.0059199) (PMID:23554996) (PMCID:PMC3595244)
Verschuren, J.J.W., Wessels, J.A., Trompet, S., Stott, D.J. , Sattar, N. , Buckley, B., Guchelaar, H.-J. and Jukema, J. (2012) Genetic variation in the SMARCA2 gene is associated with cardiovascular events. Journal of the American College of Cardiology, 59(13), E1393. (doi: 10.1016/S0735-1097(12)61394-1)
Nanchen, D. et al. (2012) Subclinical thyroid dysfunction and the risk of heart failure in older persons at high cardiovascular risk. Journal of Clinical Endocrinology and Metabolism, 97(3), pp. 852-861. (doi: 10.1210/jc.2011-1978)
Legg, L.A., Quinn, T.J. , Mahmood, F., Weir, C.J., Tierney, J., Stott, D.J. , Smith, L.N. and Langhorne, P. (2012) Nonpharmacological interventions for caregivers of stroke survivors. Stroke, 43(3), e30-e31. (doi: 10.1161/STROKEAHA.111.644914)
Poortvliet, R.K.E. et al. (2012) Blood pressure variability and cardiovascular risk in the PROspective study of pravastatin in the elderly at risk (PROSPER). PLoS ONE, 7(12), e52438. (doi: 10.1371/journal.pone.0052438) (PMID:23285043) (PMCID:PMC3527505)
Shiffman, D. et al. (2012) Genome-wide study of gene variants associated with differential cardiovascular event reduction by Pravastatin therapy. PLoS ONE, 7(5), e38240. (doi: 10.1371/journal.pone.0038240) (PMID:22666496) (PMCID:PMC3364212)
Stott, D.J. et al. (2012) RCPE UK consensus conference on 'Approaching the comprehensive management of atrial fibrillation: evolution or revolution?'. Journal of the Royal College of Physicians of Edinburgh, 42(1), pp. 34-35. (doi: 10.4997/JRCPE.2012.S01)
Stott, D.J. et al. (2012) RCPE UK consensus conference on 'Approaching the comprehensive management of atrial fibrillation: evolution or revolution?'. Journal of the Royal College of Physicians of Edinburgh, 42(Sup 4),
Trompet, S., Jukema, W., Mooijaart, S.P., Ford, I. , Stott, D.J. , Westendorp, R.G.J. and de Craen, A.J.M. (2012) Genetic variation in galectin-3 gene associates with cognitive function at old age. Neurobiology of Aging, 33(9), 2232.e1-2232.e9. (doi: 10.1016/j.neurobiolaging.2012.05.001)
Ford, I. et al. (2011) The inverse relationship between alanine aminotransferase in the normal range and adverse cardiovascular and non-cardiovascular outcomes. International Journal of Epidemiology, 40(6), pp. 1530-1538. (doi: 10.1093/ije/dyr172)
van Es, A.C.G.M. et al. (2011) Cerebral microbleeds and cognitive functioning in the PROSPER study. Neurology, 77(15), pp. 1446-1452. (doi: 10.1212/WNL.0b013e318232ab1d)
Trompet, S. et al. (2011) Replication of LDL SWAs hits in PROSPER/PHASE as validation for future (pharmaco)genetic analyses. BMC Medical Genetics, 12, p. 131. (doi: 10.1186/1471-2350-12-131)
Welsh, P. et al. (2011) Circulating interleukin-10 and risk of cardiovascular events: a prospective study in the elderly at risk. Arteriosclerosis, Thrombosis, and Vascular Biology, 31(10), pp. 2338-2344. (doi: 10.1161/ATVBAHA.111.231795) (PMID:21757655)
Mooijaart, S.P. et al. (2011) C-Reactive protein and genetic variants and cognitive decline in old age: the PROSPER Study. PLoS ONE, 6(9), e23890. (doi: 10.1371/journal.pone.0023890) (PMID:21915265) (PMCID:PMC3168438)
Quinn, T.J. , McArthur, K., Ellis, G. and Stott, D.J. (2011) Functional assessment in older people. British Medical Journal, 343, d4681. (doi: 10.1136/bmj.d4681)
Quinn, T.J. , Gallacher, J., Deary, I.J., Lowe, G.D.O., Fenton, C. and Stott, D.J. (2011) Association between circulating hemostatic measures and dementia or cognitive impairment: systematic review and meta-analyzes. Journal of Thrombosis and Haemostasis, 9(8), pp. 1475-1482. (doi: 10.1111/j.1538-7836.2011.04403.x)
Widya, R. L. et al. (2011) Increased amygdalar and hippocampal volumes in elderly obese individuals with or at risk of cardiovascular disease. American Journal of Clinical Nutrition, 93(6), pp. 1190-1195. (doi: 10.3945/ajcn.110.006304)
Rahimi, K. et al. (2011) Effect of statins on atrial fibrillation: collaborative meta-analysis of published and unpublished evidence from randomised controlled trials. British Medical Journal, 342, d1250. (doi: 10.1136/bmj.d1250)
Stott, D.J. and Handoll, H. (2011) Rehabilitation of older people after hip (proximal femoral) fracture. Cochrane Database of Systematic Reviews, 2011(8), ED000023.
Altmann-Schneider, I., Trompet, S., de Craen, A. J. M., van Es, A. C. G. M., Jukema, J. W., Stott, D.J. , Sattar, N. , Westendorp, R. G. J., van Buchem, M. A. and van der Grond, J. (2011) Cerebral Microbleeds Are Predictive of Mortality in the Elderly. Stroke, 42(3), pp. 638-644. (doi: 10.1161/STROKEAHA.110.595611)
Brady, M.C., Stott, D.J. , Norrie, J., Chalmers, C., St George, B., Sweeney, P.M. and Langhorne, P. (2011) Developing and evaluating the implementation of a complex intervention: using mixed methods to inform the design of a randomised controlled trial of an oral healthcare intervention after stroke. Trials, 12(168), (doi: 10.1186/1745-6215-12-168)
Freeman, D. J. et al. (2011) Incident venous thromboembolic events in the Prospective Study of Pravastatin in the Elderly at Risk (PROSPER). BMC Geriatrics, 11, 8. (doi: 10.1186/1471-2318-11-8) (PMID:21342490) (PMCID:PMC3053238)
Kerr, G.D., Higgins, P., Walters, M. , Ghosh, S.K., Wright, F., Langhorne, P. and Stott, D.J. (2011) Socioeconomic status and transient ischaemic attack / stroke: a prospective observational study. Cerebrovascular Diseases, 31(2), pp. 130-137. (doi: 10.1159/000321732)
Kerr, G.D., Robertson, M. and Stott, D.J. (2011) Long-term follow-up of cognitive function and activities of daily living in older people: a feasibility study in the PROSPER cohort. Open Clinical Trials Journal, 3(1), pp. 6-12. (doi: 10.2174/1876821001103010006)
Kerr, G.D., Slavin, H., Clark, D., Coupar, F., Langhorne, P. and Stott, D.J. (2011) Do vascular risk factors explain the association between socioeconomic status and stroke incidence: a meta-analysis. Cerebrovascular Diseases, 31(1), pp. 57-63. (doi: 10.1159/000320855)
Langhorne, P. and Stott, D. (2011) Letter by Langhorne and Stott Regarding Article, "Very Early Mobilization After Stroke Fast-Tracks Return to Walking: Further Results From the Phase II AVERT Randomized Controlled Trial". Stroke, 42(5), e376. (doi: 10.1161/STROKEAHA.111.613554)
Legg, L.A., Quinn, T.J. , Mahmood, F., Weir, C.J., Tierney, J., Stott, D.J. , Smith, L.N. and Langhorne, P. (2011) Non-pharmacological interventions for caregivers of stroke survivors. Cochrane Database of Systematic Reviews, 10, CD008179. (doi: 10.1002/14651858.CD008179.pub2)
Macfarlane, P.W., Murray, H., Sattar, N. , Stott, D.J. , Ford, I. , Buckley, B., Jukema, J.W., Westendorp, R.G.J. and Shepherd, J. (2011) The incidence and risk factors for new onset atrial fibrillation in the PROSPER study. Europace, 13(5), pp. 634-639. (doi: 10.1093/europace/eur016)
Mutsaerts, H.J.M.M. et al. (2011) Diastolic carotid artery wall shear stress is associated with cerebral infarcts and periventricular white matter lesions. Stroke, 42(12), pp. 3497-3501. (doi: 10.1161/STROKEAHA.111.614453)
Pons, D. et al. (2011) Genetic variation in PCAF, a key mediator in epigenetics, is associated with reduced vascular morbidity and mortality: evidence for a new concept from three independent prospective studies. Heart, 97(2), pp. 143-150. (doi: 10.1136/hrt.2010.199927)
Quinn, T.J. , Langhorne, P. and Stott, D.J. (2011) Barthel index for stroke trials: development, properties, and application. Stroke, 42(4), pp. 1146-1151. (doi: 10.1161/STROKEAHA.110.598540)
Smith, N. L. et al. (2011) Genetic predictors of fibrin D-Dimer levels in healthy adults. Circulation, 123(17), pp. 1864-1872. (doi: 10.1161/CIRCULATIONAHA.110.009480)
Wain, L.V. et al. (2011) Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure. Nature Genetics, 43(10), pp. 1005-1011. (doi: 10.1038/ng.922)
Schofield, I., Stott, D.J. , Tolson, D., McFadyen, A., Monaghan, J. and Nelson, D. (2010) Screening for cognitive impairment in older people attending accident and emergency using the 4-item abbreviated mental test. European Journal of Emergency Medicine, 17(6), pp. 340-342. (doi: 10.1097/MEJ.0b013e32833777ab)
Caslake, M.J. et al. (2010) Lipoprotein-associated phospholipase A2 inflammatory biomarkers, and risk of cardiovascular disease in the Prospective Study of Pravastatin in the Elderly at Risk (PROSPER). Atherosclerosis, 210(1), pp. 28-34. (doi: 10.1016/j.atherosclerosis.2009.10.041)
Sattar, N. et al. (2010) Statins and risk of incident diabetes: a collaborative meta-analysis of randomised statin trials. Lancet, 375(9716), pp. 735-742. (doi: 10.1016/S0140-6736(09)61965-6)
Trompet, S. et al. (2010) Pravastatin and cognitive function in the elderly. Results of the PROSPER study. Journal of Neurology, 257(1), pp. 85-90. (doi: 10.1007/s00415-009-5271-7)
Welsh, P. et al. (2010) Unraveling the directional link between adiposity and inflammation: a bidirectional mendelian randomization approach. Journal of Clinical Endocrinology and Metabolism, 95(1), pp. 93-99. (doi: 10.1210/jc.2009-1064)
Langhorne, P. , Stott, D. , Knight, A., Bernhardt, J., Barer, D. and Watkins, C. (2010) Very Early Rehabilitation or Intensive Telemetry after Stroke: A Pilot Randomised Trial. Cerebrovascular Diseases, 29(4), pp. 352-360. (doi: 10.1159/000278931)
Legg, L.A., Langhorne, P. , Tierney, J., Stott, D.J. , Weir, C. and Smith, L.N. (2010) Non-pharmacological interventions for caregivers of stroke survivors. Cochrane Database of Systematic Reviews, 1, CD008179. (doi: 10.1002/14651858.CD008179)
Stott, D.J. et al. (2010) Activation of Hemostasis and Decline in Cognitive Function in Older People. Arteriosclerosis, Thrombosis, and Vascular Biology, 30(3), pp. 605-611. (doi: 10.1161/ATVBAHA.109.199448)
Mcmurdo, M.E.T., Price, R.J.G., Shields, M., Potter, J. and Stott, D.J. (2009) Should oral nutritional supplementation be given to undernourished older people upon hospital discharge? A controlled trial. Journal of the American Geriatrics Society, 57(12), pp. 2239-2245. (doi: 10.1111/j.1532-5415.2009.02568.x)
Stott, D.J., Welsh, P.I., Rumley, A., Robertson, M., Ford, I. , Sattar, N.A., Westendorp, R.G.J., Jukema, J.W., Cobbe, S. and Lowe, G.D. (2009) Adipocytokines and risk of stroke in older people: a nested case-control study. International Journal of Epidemiology, 38(1), pp. 253-261. (doi: 10.1093/ije/dyn215)
Welsh, P. et al. (2009) Leptin Predicts Diabetes but Not Cardiovascular Disease Results from a large prospective study in an elderly population. Diabetes Care, 32(2), pp. 308-310. (doi: 10.2337/dc08-1458)
Ford, I. et al. (2009) Reduced glomerular filtration rate and its association with clinical outcome in older patients at risk of vascular events: secondary analysis. PLoS Medicine, 6(1), e1000016. (doi: 10.1371/journal.pmed.1000016)
Gordon, A., Hu, H., Byrne, A. and Stott, D.J. (2009) Dementia screening in acute medical and geriatric hospital admissions. Psychiatric Bulletin, 33(2), pp. 52-54. (doi: 10.1192/pb.bp.107.016550)
Kerr, G., Ray, G., Stott, D., Wu, O. and Langhorne, P. (2009) Elevated Troponin after Stroke: A Systematic Review. Cerebrovascular Diseases, 28(3), pp. 220-226. (doi: 10.1159/000226773)
Kerr, G., Sellars, C., Bowie, L., Bagg, J., Sweeney, M., Langhorne, P. and Stott, D.J. (2009) Xerostomia after acute stroke. Cerebrovascular Diseases, 28(6), pp. 624-626. (doi: 10.1159/000253147)
Sattar, N.A. et al. (2009) Are markers of inflammation more strongly associated with risk for fatal than for nonfatal vascular events? PLoS Medicine, 6(6), e1000099. (doi: 10.1371/journal.pmed.1000099)
Sattar, N. et al. (2009) Are elevated circulating intercellular adhesion molecule 1 levels more strongly predictive of diabetes than vascular risk? Outcome of a prospective study in the elderly. Diabetologia, 52(2), pp. 235-239.
Stott, D.J., Falconer, A., Miller, H., Tilston, J.C. and Langhorne, P. (2009) Urinary tract infection after stroke. QJM: An International Journal of Medicine, 102(4), pp. 243-249. (doi: 10.1093/qjmed/hcp012)
Trompet, S., de Craen, A.J.M., Mooijaart, S., Stott, D.J. , Ford, I. , Sattar, N.A. , Jukema, W. and Westendorp, R.G.J. (2009) High innate production capacity of proinflammatory cytokines increases risk for death from cancer: results of the PROSPER study. Clinical Cancer Research, 15(24), pp. 7744-7748. (doi: 10.1158/1078-0432.CCR-09-2152)
Welsh, P., Barber, M., Langhorne, P., Rumley, A., Lowe, G. and Stott, D. (2009) Associations of Inflammatory and Haemostatic Biomarkers with Poor Outcome in Acute Ischaemic Stroke. Cerebrovascular Diseases, 27(3), pp. 247-253. (doi: 10.1159/000196823)
Sattar, N. et al. (2008) Can metabolic syndrome usefully predict cardiovascular disease and diabetes? Outcome data from two prospective studies. Lancet, 371(9628), pp. 1927-1935. (doi: 10.1016/S0140-6736(08)60602-9)
Braid, V., Barber, M., Mitchell, S., Martin, B., Granat, M. and Stott, D. (2008) Randomised controlled trial of electrical stimulation of the quadriceps after proximal femoral fracture. Aging Clinical and Experimental Research, 20(1), pp. 62-66.
Knussen, C., Tolson, D., Brogan, C., Swan, I., Stott, D. and Sullivan, F. (2008) Family caregivers of older relatives: ways of coping and change in distress. Psychology, Health and Medicine, 13(3), pp. 274-290. (doi: 10.1080/13548500701405483)
Stott, D., Falconer, A., Kerr, G., Murray, H., Trompet, S., Westendorp, R., Buckley, B., De Craen, A., Sattar, N. and Ford, I. (2008) Does Low to Moderate Alcohol Intake Protect Against Cognitive Decline in Older People? Journal of the American Geriatrics Society, 56(12), pp. 2217-2224. (doi: 10.1111/j.1532-5415.2008.02007.x)
Stott, D., Langhorne, P. and Knight, P. (2008) Multidisciplinary care for elderly people in the community. Lancet, 371(9614), pp. 699-700. (doi: 10.1016/S0140-6736(08)60317-7)
Trompet, S. et al. (2008) Lymphotoxin-alpha C804A polymorphism is a risk factor for stroke. The PROSPER study. Experimental Gerontology, 43(8), pp. 801-805. (doi: 10.1016/j.exger.2008.04.006)
Trompet, S. et al. (2008) Genetic variation in the interleukin-1 beta-converting enzyme associates with cognitive function. The PROSPER study. Brain, 131(4), pp. 1069-1077. (doi: 10.1093/brain/awn023)
Packard, C.J. et al. (2007) Association between apolipoprotein E4 and cognitive decline in elderly adults. Journal of the American Geriatrics Society, 55(11), pp. 1777-1785. (doi: 10.1111/j.1532-5415.2007.01415.x)
Barber, M., Barlow, N., Macfarlane, P., Morton, J., Roditi, G. and Stott, D. (2007) Elevated troponin levels are associated with sympathoadrenal activation in acute ischaemic stroke. Cerebrovascular Diseases, 23, pp. 260-266. (doi: 10.1159/000098325)
Barber, M., Langhorne, P., Stott, D. and Wright, F. (2007) Early neurological deterioration in acute stroke. QJM: An International Journal of Medicine, 100(1), p. 62.
Langhorne, P., Stott, D. and Wright, F. (2007) Improved survival after stroke. Cerebrovascular Diseases, 23(4), pp. 320-321.
Legg, L., Stott, D. , Ellis, G. and Sellars, C. (2007) Volunteer Stroke Service (VSS) groups for patients with communication difficulties after stroke: a qualitative analysis of the value of groups to their users. Clinical Rehabilitation, 21(9), pp. 794-804.
McCormick, L. and Stott, D. (2007) Anaemia in elderly patients. Clinical Medicine, 7(5), pp. 501-504.
Sattar, N. et al. (2007) C-reactive protein and prediction of coronary heart disease and global vascular events in the prospective study of pravastatin in the elderly at risk (PROSPER). Circulation, 115(8), pp. 981-989. (doi: 10.1161/CIRCULATIONAHA.106.643114)
Sellars, C., Bowie, L., Bagg, J. , Sweeney, M.P., Miller, H., Tilston, J., Langhorne, P. and Stott, D.J. (2007) Risk factors for chest infection in acute stroke: a prospective cohort study. Stroke, 38(8), pp. 2284-2291. (doi: 10.1161/STROKEAHA.106.478156)
Barber, M., Langhorne, P. , Rumley, A., Lowe, G.D.O. and Stott, D.J. (2006) D-dimer predicts early clinical progression in ischemic stroke: confirmation using routine clinical assays. Stroke, 37(4), pp. 1113-1115. (doi: 10.1161/01.STR.0000209240.63821.1a)
Agnew, R., Bowman, A., Burrow, K., Buttery, A., Knight, P., Mitchell, S., Ramsay, S. and Stott, D. (2006) Comprehensive geriatric assessment and home-based rehabilitation for elderly people with a history of recurrent non-elective hospital admissions. Age and Ageing, 35(5), pp. 487-491.
de Craen, A., Stott, D. and Westendorp, R. (2006) Homocysteine, B vitamins, and cardiovascular disease. New England Journal of Medicine, 355(2), pp. 205-206.
Gordon, M. et al. (2006) A means to an endpoint. Good Clinical Practice Journal, 13(10), pp. 25-29.
Stott, D. (2006) Blood pressure in very elderly people. Journal of Hypertension, 24(2), pp. 263-264.
Stott, D. (2006) Cognitive decline in ageing. Asian Journal of Gerontology and Geriatrics, 1(1), pp. 21-25.
Stott, D. J. et al. (2005) Randomized controlled trial of homocysteine-lowering vitamin treatment in elderly patients with vascular disease. American Journal of Clinical Nutrition, 82(6), pp. 1320-1326. (doi: 10.1093/ajcn/82.6.1320) (PMID:16332666)
Knussen, C., Tolson, D., Swan, I., Stott, D. , Brogan, C. and Sullivan, F. (2005) The social and psychological impact of an older relative's hearing difficulties: factors associated with change. Psychology, Health and Medicine, 10(1), pp. 57-63. (doi: 10.1080/13548500512331315361)
Barber, M., Lowe, G., Rumley, A., Scott, J., Stott, D. and Tait, R. (2005) Dementia in subjects with atrial fibrillation; haemostatic function and the role of anticoagulation (vol 33, pg 10, 2004). Age and Ageing, 34,
de Craen, A., Frolich, M., Gussekloo, J., Jolles, J., Mooijaart, S., Stott, D. and Westendorp, R. (2005) Homocysteine, vitamin B-12, and folic acid and the risk of cognitive decline in old age: the Leiden 85-Plus Study. American Journal of Clinical Nutrition, 82, pp. 866-871.
Kamper, A., Stott, D. , Hyland, M., Murray, H. and Ford, I. (2005) Predictors of functional decline in elderly people with vascular risk factors or disease. Age and Ageing, 34, pp. 450-455. (doi: 10.1093/ageing/afi137)
Knussen, C., Tolson, D., Swan, I., Stott, D. and Brogan, C. (2005) Stress proliferation in caregivers: The relationships between caregiving stressors and deterioration in family relationships. Psychology and Health, 20, pp. 207-221. (doi: 10.1080/08870440512331334013)
Packard, C.J. et al. (2005) Plasma lipoproteins and apolipoproteins as predictors of cardiovascular risk and treatment benefit in the PROspective Study of Pravastatin in the Elderly at Risk (PROSPER). Circulation, 112, pp. 3058-3065. (doi: 10.1161/CIRCULATIONAHA.105.526848)
Barber, M., Tait, R.C. , Scott, J., Rumley, A., Lowe, G. and Stott, D.J. (2004) Dementia in subjects with atrial fibrillation: hemostatic function and the role of anticoagulation. Journal of Thrombosis and Haemostasis, 2(11), pp. 1873-1878. (doi: 10.1111/j.1538-7836.2004.00993.x) (PMID:15550013)
Knussen, C., Tolson, D., Swan, I.R.C., Stott, D.J. , Brogan, C.A. and Sullivan, F. (2004) The social and psychological impact of an older relative's hearing difficulties. Psychology, Health and Medicine, 9(1), pp. 3-15. (doi: 10.1080/13548500310001637715)
Barber, M., Fail, M., Langhorne, P., Shields, M. and Stott, D. (2004) Validity and reliability of estimating the Scandinavian Stroke Scale score from medical records. Cerebrovascular Diseases, 17(02-Mar), pp. 224-227.
Barber, M., Langhorne, P., Roditi, G. and Stott, D. (2004) Poor outcome in primary intracerebral haemorrhage: results of a matched comparison. Postgraduate Medical Journal, 80(940), pp. 89-92.
Barber, M., Langhorne, P. and Stott, D. (2004) Barriers to delivery of thrombolysis for acute stroke. Age and Ageing, 33(2), pp. 94-95.
Barber, M., Langhorne, P. and Stott, D. (2004) An internationally agreed definition of progressing stroke. Cerebrovascular Diseases, 18(3), pp. 255-256.
Barber, M., Langhorne, P., Stott, D. and Wright, F. (2004) Predictors of early neurological deterioration after ischaemic stroke: A case-control study. Gerontology, 50(2), pp. 102-109.
Barber, M. and Stott, D. (2004) Validity of the Telephone Interview for Cognitive Status (TICS) in post-stroke subjects. International Journal of Geriatric Psychiatry, 19(1), pp. 75-79.
Barber, M., Langhorne, P. , Rumley, A., Lowe, G.D.O. and Stott, D.J. (2004) Hemostatic function and progressing ischemic stroke: D-dimer predicts early clinical progression. Stroke, 35(6), pp. 1421-1425. (doi: 10.1161/01.STR.0000126890.63512.41)
Chouliara, Z., Kearney, N., Stott, D. , Molassiotis, A. and Miller, M. (2004) Perceptions of older people with cancer of information, decision making and treatment: a systematic review of selected literature. Annals of Oncology, 15(11), pp. 1596-1602.
Chouliara, Z., Kearney, N., Worth, A. and Stott, D. (2004) Challenges in conducting research with hospitalized older people with cancer: drawing from the experience of an ongoing interview-based project. European Journal of Cancer Care, 13, pp. 409-415.
Chouliara, Z., Miller, M., Stott, D. , Molassiotis, A., Twelves, C. and Kearney, N. (2004) Older people with cancer: perceptions and feelings about information, decision-making and treatment--a pilot study. European Journal of Oncology Nursing, 8(3), pp. 257-261. (doi: 10.1016/j.ejon.2003.12.010)
Das, K., Fail, M., Gibb, A., Hill, A., Kane, C., Moylan, T., Stott, D. , Toye, D. and Wolstencroft, K. (2004) Assessment of cognitive function on older hospital inpatients: is the Telephone Interview for Cognitive Status (TICS-M) a useful alternative to the Mini Mental State Examination? International Journal of Geriatric Psychiatry, 19(10), pp. 1008-1009.
Adler, B. and Stott, D. (2003) How far to investigate older people? Clinical Medicine, 3(5), pp. 418-422.
Adler, B. and Stott, D. (2003) Investigating older people - In response. Clinical Medicine, 3(6), pp. 592-593.
Barber, M., Braid, V., Camacho-Hubner, C., Gilmore, D., Grant, S., Jenkins, P. and Stott, D. (2003) IGF-I levels, leg extensor power and physical performance after proximal femoral fracture. Age and Ageing, 32(6), pp. 678-680.
Cameron, M., Granat, M., Pandyan, A., Powell, J. and Stott, D. (2003) Contractures in the post-stroke wrist: a pilot study of its time course of development and its association with upper limb recovery. Clinical Rehabilitation, 17, pp. 88-95. (doi: 10.1191/0269215503cr587oa)
Fraser, N., Rowley, G., Field, M. and Stott, D. (2003) The V-H gene repertoire of splenic B cells and somatic hypermutation in systemic lupus erythematosus. Arthritis Research and Therapy, 5, R114-R121. (doi: 10.1186/ar627)
Barber, M., Braid, V., Granat, M., Grant, S., Martin, B., Mitchell, S. and Stott, D. (2002) Electrical stimulation of quadriceps during rehabilitation following proximal femoral fracture. International Journal of Rehabilitation Research, 25(1), pp. 61-63.
Ford, I. et al. (2002) A prospective study of pravastatin in the elderly at risk (PROSPER): Screening experience and baseline characteristics. Current Controlled Trials in Cardiovascular Medicine, 3, p. 8. (doi: 10.1186/1468-6708-3-8)
Houx, P.J. et al. (2002) Testing cognitive function in elderly populations: the PROSPER study. Journal of Neurology, Neurosurgery and Psychiatry, 73(4), pp. 385-389. (doi: 10.1136/jnnp.73.4.385)
Shepherd, J. et al. (2002) Pravastatin in elderly individuals at risk of vascular disease (PROSPER): a randomised controlled trial. Lancet, 360(9346), pp. 1623-1630. (doi: 10.1016/S0140-6736(02)11600-X)
Stott, D.J. , Kerr, G. and Carman, W.F. (2002) Nosocomial transmission of influenza. Occupational Medicine, 52(5), pp. 249-253. (doi: 10.1093/occmed/52.5.249)
Stott, D. and Taylor, J. (2002) Chronic heart failure and cognitive impairment: co-existence of conditions or true association? European Journal of Heart Failure, 4(1), pp. 7-9.
Barber, M. and Stott, D. (2001) Systematic reviews. Age and Ageing, 30(2), pp. 127-128. (doi: 10.1093/ageing/30.2.127)
Carman, W., Elder, A. and Stott, D. (2001) Influenza in old age. Age and Ageing, 30(5), pp. 361-363.
Grant, S., Martin, B., Mitchell, S. and Stott, D. (2001) Randomized controlled trial of quadriceps training after proximal femoral fracture. Clinical Rehabilitation, 15, pp. 282-290.
Stone, S., Kibbler, C., Bowman, C. and Stott, D. (2001) Controlling infection in British nursing homes - It is time for a national strategy. British Medical Journal, 322(7285), p. 506.
Stott, D.J. , Spilg, E., Campbell, A.M., Rumley, A., Mansoor, M.A. and Lowe, G.D.O. (2001) Haemostasis in ischaemic stroke and vascular dementia. Blood Coagulation and Fibrinolysis, 12(8), pp. 651-657.
Bowman, A. and Stott, D. (2000) Blood pressure and aging. Journal of Human Hypertension, 14(12), pp. 771-772.
Book Sections
Harrison, J. K. , Quinn, T. J. and Stott, D. J. (2012) Planning cardiovascular investigations and management of older people. In: Stott, D.J. and Lowe, G.D.O. (eds.) Cardiovascular Disease and Health in the Older Patient. Wiley-Blackwell: Chichester, pp. 376-393. ISBN 9780470973721 (doi: 10.1002/9781118451786.ch16)
Quinn, T.J. and Stott, D.J. (2012) Cardiac ageing and systemic disorders. In: Sinclair, A.J., Morley, J.E. and Vellas, B. (eds.) Pathy's Principle and Practice of Geriatric Medicine. Wiley-Blackwell: Chichester, UK, pp. 405-412. ISBN 9780470683934 (doi: 10.1002/9781119952930.ch35)
Trompet, S. et al. (2007) Genetic variation in the interleukin-10 gene promoter and risk of coronary and cerebrovascular events - The PROSPER study. In: Rattan, S. and Akman, S. (eds.) Biogerontology: Mechanisms and Interventions. Series: Annals of the New York Academy of Sciences (1100). Blackwell Publishing: Oxford, pp. 189-198. ISBN 978-1-57331-679-8 (doi: 10.1196/annals.1395.018)
Conference or Workshop Item
Kendall, M., Cowey, E. , Murray, S.A., Barber, M., Borthwick, S., Boyd, K., McAlpine, C., Stott, D. and Mead, G. (2017) Experiences and Multi-Dimensional Needs of People With Major Stroke and their Family Carers. British Geriatrics Society Autumn Meeting, Glasgow, UK, 23-25 Nov 2016. i46. (doi: 10.1093/ageing/afx070.162)
Barber, M., Kendall, M., Cowey, E. , Borthwick, S., Boyd, K., McAlpine, C., Stott, D.J. , Mead, G.E. and Murray, S.A. (2017) Is Palliative Care Appropriate for All People After Major Stroke. 3rd European Stroke Organisation Conference 2017, Prague, Czech Republic, 16-18 May 2017. p. 426. (doi: 10.1177/2396987317705242)