2024

De Lucca Camargo, L. et al. (2024) Protein disulfide isomerase-mediated transcriptional upregulation of Nox1 contributes to vascular dysfunction in hypertension. Journal of Hypertension, 42(6), pp. 984-999. (doi: 10.1097/hjh.0000000000003677) (PMID:38690903)

Tobias, E. S. et al. (2024) SEC31A may be associated with pituitary hormone deficiency and gonadal dysgenesis. Endocrine, 84, pp. 345-349. (doi: 10.1007/s12020-024-03701-x) (PMID:38400880)

2023

Camargo, L. L. and Touyz, R. M. (2023) Phenotype-specific induced pluripotent stem cell–derived vascular smooth muscle cells to model vascular disease: implications of differentiation protocols. Hypertension, 80(4), pp. 754-756. (doi: 10.1161/HYPERTENSIONAHA.123.20871) (PMID:36921028)

2022

Gao, X. et al. (2022) Palmitoylation regulates cellular distribution of and transmembrane Ca flux through TrpM7. Cell Calcium, 106, 102639. (doi: 10.1016/j.ceca.2022.102639) (PMID:36027648)

Rios, F. J. et al. (2022) TRPM7 deficiency exacerbates cardiovascular and renal damage induced by aldosterone-salt. Communications Biology, 5, 746. (doi: 10.1038/s42003-022-03715-z) (PMID:35882956) (PMCID:PMC9325869)

2020

Anagnostopoulou, A., Camargo, L. L. , Rodrigues, D., Montezano, A. C. and Touyz, R. M. (2020) Importance of cholesterol-rich microdomains in the regulation of Nox isoforms and redox signaling in human vascular smooth muscle cells. Scientific Reports, 10, 17818. (doi: 10.1038/s41598-020-73751-4) (PMID:33082354) (PMCID:PMC7575553)

Zou, Z.-G. et al. (2020) Epidermal growth factor signaling through transient receptor potential melastatin 7 cation channel regulates vascular smooth muscle cell function. Clinical Science, 134(15), pp. 2019-2035. (doi: 10.1042/CS20200827) (PMID:32706027) (PMCID:PMC8299307)

Touyz, R. , Rios, F. , Alves-Lopes, R., Neves, K. B. , De Lucca Camargo, L. and Montezano, A. C. (2020) Oxidative stress: a unifying paradigm in hypertension. Canadian Journal of Cardiology, 36, pp. 659-670. (doi: 10.1016/j.cjca.2020.02.081) (PMID:32389339) (PMCID:PMC7225748)

Rios, F. J. et al. (2020) Chanzyme TRPM7 protects against cardiovascular inflammation and fibrosis. Cardiovascular Research, 116(3), pp. 721-735. (doi: 10.1093/cvr/cvz164) (PMID:31250885) (PMCID:PMC7252442)

2019

Touyz, R. M. , Anagnostopoulou, A., Rios, F. , Montezano, A. C. and De Lucca Camargo, L. (2019) NOX5: molecular biology and pathophysiology. Experimental Physiology, 104(5), pp. 605-616. (doi: 10.1113/EP086204) (PMID:30801870) (PMCID:PMC6519284)

Touyz, R. M. and De Lucca Camargo, L. (2019) Microglia, the missing link in the brain-gut-hypertension axis. Circulation Research, 124(5), pp. 671-673. (doi: 10.1161/CIRCRESAHA.119.314718) (PMID:30817265)

Touyz, R. M. , Anagnostopoulou, A., De Lucca Camargo, L. , Rios, F. J. and Montezano, A. C. (2019) Vascular biology of superoxide-generating NADPH oxidase 5 (Nox5)- implications in hypertension and cardiovascular disease. Antioxidants and Redox Signaling, 30(7), pp. 1027-1040. (doi: 10.1089/ars.2018.7583) (PMID:30334629) (PMCID:PMC6354601)

Gimenez, M. et al. (2019) Redox activation of Nox1 (NADPH Oxidase 1) involves an intermolecular disulfide bond between protein disulfide isomerase and p47phox in vascular smooth muscle cells. Arteriosclerosis, Thrombosis, and Vascular Biology, 39(2), pp. 224-236. (doi: 10.1161/ATVBAHA.118.311038) (PMID:30580571) (PMCID:PMC6344286)

de Lucca Camargo, L. and Touyz, R. M. (2019) Reactive oxygen species. In: Touyz, R. M. and Delles, C. (eds.) Textbook of Vascular Medicine. Springer: Cham, pp. 127-136. ISBN 9783030164805 (doi: 10.1007/978-3-030-16481-2_12)

2018

De Lucca Camargo, L. et al. (2018) Vascular Nox (NADPH oxidase) compartmentalization, protein hyperoxidation, and endoplasmic reticulum stress response in hypertension. Hypertension, 72(1), pp. 235-246. (doi: 10.1161/HYPERTENSIONAHA.118.10824) (PMID:29844144) (PMCID:PMC6004120)

Montezano, A. C. et al. (2018) NADPH oxidase 5 is a pro‐contractile Nox isoform and a point of cross‐talk for calcium and redox signaling‐implications in vascular function. Journal of the American Heart Association, 7(12), e009388. (doi: 10.1161/JAHA.118.009388) (PMID:29907654) (PMCID:PMC6220544)

Montezano, A. C. et al. (2018) NADPH Oxidase 5 is a pro‐contractile Nox isoform and a point of cross‐talk for calcium and redox signaling‐implications in vascular function. Journal of the American Heart Association, 7(12), (doi: 10.1161/JAHA.118.009388) (PMID:29907654) (PMCID:PMC6220544)

Touyz, R. M. , Alves-Lopes, R. , Rios, F. J. , De Lucca Camargo, L. , Anagnostopoulou, A., Arner, A. and Montezano, A. C. (2018) Vascular smooth muscle contraction in hypertension. Cardiovascular Research, 114(4), pp. 529-539. (doi: 10.1093/cvr/cvy023) (PMID:29394331) (PMCID:PMC5852517)

2016

Touyz, R. , Anagnostopoulou, A., De Lucca Camargo, L. and Montezano, A. (2016) Novel biosensors reveal a shift in the redox paradigm from oxidative to reductive stress in heart disease. Circulation Research, 119(9), pp. 969-971. (doi: 10.1161/circresaha.116.309854) (PMID:27737937)

Rios, F. J. , Lopes, R. A. , Neves, K. B., De Lucca Camargo, L. , Montezano, A. C. and Touyz, R. M. (2016) Off-target vascular effects of cholesteryl ester transfer protein inhibitors involve redox-sensitive and signal transducer and activator of transcription 3-dependent pathways. Journal of Pharmacology and Experimental Therapeutics, 357(2), pp. 415-422. (doi: 10.1124/jpet.115.230748) (PMID:26941168)

2015

Montezano, A. C., Tsiropoulou, S., Dulak-Lis, M., Harvey, A., De Lucca Camargo, L. and Touyz, R. M. (2015) Redox signaling, Nox5 and vascular remodeling in hypertension. Current Opinion in Nephrology and Hypertension, 24(5), pp. 425-433. (doi: 10.1097/MNH.0000000000000153) (PMID:26197203) (PMCID:PMC4727501)

De Lucca Camargo, L. et al. (2015) Peripheral neurokinin-1 receptors contribute to kaolin-induced acute monoarthritis in rats. Neuroimmunomodulation, 22(6), pp. 373-384. (doi: 10.1159/000381549) (PMID:26088412)

Androwiki, A. C.D., De Lucca Camargo, L. , Sartoretto, S., Couto, G. K., Ribeiro, I. M.R., Veríssimo-Filho, S., Rossoni, L. V. and Lopes, L. R. (2015) Protein disulfide isomerase expression increases in resistance arteries during hypertension development. Effects on Nox1 NADPH oxidase signaling. Frontiers in Chemistry, 3(24), pp. 1-10. (doi: 10.3389/fchem.2015.00024) (PMID:25870854) (PMCID:PMC4375999)

2014

Santos, C. X.C., Nabeebaccus, A. A., Shah, A. M., De Lucca Camargo, L. , Filho, S. V. and Lopes, L. R. (2014) Endoplasmic reticulum stress and Nox-mediated reactive oxygen species signaling in the peripheral vasculature : potential role in hypertension. Antioxidants and Redox Signaling, 20(1), pp. 121-134. (doi: 10.1089/ars.2013.5262) (PMID:23472786) (PMCID:PMC3880927)

2013

De Lucca Camargo, L. , Babelova, A., Mieth, A., Weigert, A., Mooz, J., Rajalingam, K., Heide, H., Wittig, I., Rossetti Lopes, L. and Brandes, R. P. (2013) Endo-PDI is required for TNFα-induced angiogenesis. Free Radical Biology and Medicine, 65, pp. 1398-1407. (doi: 10.1016/j.freeradbiomed.2013.09.028) (PMID:24103565)

2012

Chignalia, A. Z. et al. (2012) Testosterone induces vascular smooth muscle cell migration by NADPH oxidase and c-Src-dependent pathways. Hypertension, 59(6), pp. 1263-1271. (doi: 10.1161/HYPERTENSIONAHA.111.180620) (PMID:22566500)

Denadai-Souza, A., De Lucca Camargo, L. , Ribela, M. T.C.P., Keeble, J. E., Costa, S. K.P. and Muscará, M. N. (2012) Participation of peripheral tachykinin NK1 receptors in the carrageenan-induced inflammation of the rat temporomandibular joint. European journal of pain, 13, pp. 812-819. (doi: 10.1016/j.ejpain.2008.09.012) (PMID:18976941)

Articles

De Lucca Camargo, L. et al. (2024) Protein disulfide isomerase-mediated transcriptional upregulation of Nox1 contributes to vascular dysfunction in hypertension. Journal of Hypertension, 42(6), pp. 984-999. (doi: 10.1097/hjh.0000000000003677) (PMID:38690903)

Tobias, E. S. et al. (2024) SEC31A may be associated with pituitary hormone deficiency and gonadal dysgenesis. Endocrine, 84, pp. 345-349. (doi: 10.1007/s12020-024-03701-x) (PMID:38400880)

Camargo, L. L. and Touyz, R. M. (2023) Phenotype-specific induced pluripotent stem cell–derived vascular smooth muscle cells to model vascular disease: implications of differentiation protocols. Hypertension, 80(4), pp. 754-756. (doi: 10.1161/HYPERTENSIONAHA.123.20871) (PMID:36921028)

Gao, X. et al. (2022) Palmitoylation regulates cellular distribution of and transmembrane Ca flux through TrpM7. Cell Calcium, 106, 102639. (doi: 10.1016/j.ceca.2022.102639) (PMID:36027648)

Rios, F. J. et al. (2022) TRPM7 deficiency exacerbates cardiovascular and renal damage induced by aldosterone-salt. Communications Biology, 5, 746. (doi: 10.1038/s42003-022-03715-z) (PMID:35882956) (PMCID:PMC9325869)

Anagnostopoulou, A., Camargo, L. L. , Rodrigues, D., Montezano, A. C. and Touyz, R. M. (2020) Importance of cholesterol-rich microdomains in the regulation of Nox isoforms and redox signaling in human vascular smooth muscle cells. Scientific Reports, 10, 17818. (doi: 10.1038/s41598-020-73751-4) (PMID:33082354) (PMCID:PMC7575553)

Zou, Z.-G. et al. (2020) Epidermal growth factor signaling through transient receptor potential melastatin 7 cation channel regulates vascular smooth muscle cell function. Clinical Science, 134(15), pp. 2019-2035. (doi: 10.1042/CS20200827) (PMID:32706027) (PMCID:PMC8299307)

Touyz, R. , Rios, F. , Alves-Lopes, R., Neves, K. B. , De Lucca Camargo, L. and Montezano, A. C. (2020) Oxidative stress: a unifying paradigm in hypertension. Canadian Journal of Cardiology, 36, pp. 659-670. (doi: 10.1016/j.cjca.2020.02.081) (PMID:32389339) (PMCID:PMC7225748)

Rios, F. J. et al. (2020) Chanzyme TRPM7 protects against cardiovascular inflammation and fibrosis. Cardiovascular Research, 116(3), pp. 721-735. (doi: 10.1093/cvr/cvz164) (PMID:31250885) (PMCID:PMC7252442)

Touyz, R. M. , Anagnostopoulou, A., Rios, F. , Montezano, A. C. and De Lucca Camargo, L. (2019) NOX5: molecular biology and pathophysiology. Experimental Physiology, 104(5), pp. 605-616. (doi: 10.1113/EP086204) (PMID:30801870) (PMCID:PMC6519284)

Touyz, R. M. and De Lucca Camargo, L. (2019) Microglia, the missing link in the brain-gut-hypertension axis. Circulation Research, 124(5), pp. 671-673. (doi: 10.1161/CIRCRESAHA.119.314718) (PMID:30817265)

Touyz, R. M. , Anagnostopoulou, A., De Lucca Camargo, L. , Rios, F. J. and Montezano, A. C. (2019) Vascular biology of superoxide-generating NADPH oxidase 5 (Nox5)- implications in hypertension and cardiovascular disease. Antioxidants and Redox Signaling, 30(7), pp. 1027-1040. (doi: 10.1089/ars.2018.7583) (PMID:30334629) (PMCID:PMC6354601)

Gimenez, M. et al. (2019) Redox activation of Nox1 (NADPH Oxidase 1) involves an intermolecular disulfide bond between protein disulfide isomerase and p47phox in vascular smooth muscle cells. Arteriosclerosis, Thrombosis, and Vascular Biology, 39(2), pp. 224-236. (doi: 10.1161/ATVBAHA.118.311038) (PMID:30580571) (PMCID:PMC6344286)

De Lucca Camargo, L. et al. (2018) Vascular Nox (NADPH oxidase) compartmentalization, protein hyperoxidation, and endoplasmic reticulum stress response in hypertension. Hypertension, 72(1), pp. 235-246. (doi: 10.1161/HYPERTENSIONAHA.118.10824) (PMID:29844144) (PMCID:PMC6004120)

Montezano, A. C. et al. (2018) NADPH oxidase 5 is a pro‐contractile Nox isoform and a point of cross‐talk for calcium and redox signaling‐implications in vascular function. Journal of the American Heart Association, 7(12), e009388. (doi: 10.1161/JAHA.118.009388) (PMID:29907654) (PMCID:PMC6220544)

Montezano, A. C. et al. (2018) NADPH Oxidase 5 is a pro‐contractile Nox isoform and a point of cross‐talk for calcium and redox signaling‐implications in vascular function. Journal of the American Heart Association, 7(12), (doi: 10.1161/JAHA.118.009388) (PMID:29907654) (PMCID:PMC6220544)

Touyz, R. M. , Alves-Lopes, R. , Rios, F. J. , De Lucca Camargo, L. , Anagnostopoulou, A., Arner, A. and Montezano, A. C. (2018) Vascular smooth muscle contraction in hypertension. Cardiovascular Research, 114(4), pp. 529-539. (doi: 10.1093/cvr/cvy023) (PMID:29394331) (PMCID:PMC5852517)

Touyz, R. , Anagnostopoulou, A., De Lucca Camargo, L. and Montezano, A. (2016) Novel biosensors reveal a shift in the redox paradigm from oxidative to reductive stress in heart disease. Circulation Research, 119(9), pp. 969-971. (doi: 10.1161/circresaha.116.309854) (PMID:27737937)

Rios, F. J. , Lopes, R. A. , Neves, K. B., De Lucca Camargo, L. , Montezano, A. C. and Touyz, R. M. (2016) Off-target vascular effects of cholesteryl ester transfer protein inhibitors involve redox-sensitive and signal transducer and activator of transcription 3-dependent pathways. Journal of Pharmacology and Experimental Therapeutics, 357(2), pp. 415-422. (doi: 10.1124/jpet.115.230748) (PMID:26941168)

Montezano, A. C., Tsiropoulou, S., Dulak-Lis, M., Harvey, A., De Lucca Camargo, L. and Touyz, R. M. (2015) Redox signaling, Nox5 and vascular remodeling in hypertension. Current Opinion in Nephrology and Hypertension, 24(5), pp. 425-433. (doi: 10.1097/MNH.0000000000000153) (PMID:26197203) (PMCID:PMC4727501)

De Lucca Camargo, L. et al. (2015) Peripheral neurokinin-1 receptors contribute to kaolin-induced acute monoarthritis in rats. Neuroimmunomodulation, 22(6), pp. 373-384. (doi: 10.1159/000381549) (PMID:26088412)

Androwiki, A. C.D., De Lucca Camargo, L. , Sartoretto, S., Couto, G. K., Ribeiro, I. M.R., Veríssimo-Filho, S., Rossoni, L. V. and Lopes, L. R. (2015) Protein disulfide isomerase expression increases in resistance arteries during hypertension development. Effects on Nox1 NADPH oxidase signaling. Frontiers in Chemistry, 3(24), pp. 1-10. (doi: 10.3389/fchem.2015.00024) (PMID:25870854) (PMCID:PMC4375999)

Santos, C. X.C., Nabeebaccus, A. A., Shah, A. M., De Lucca Camargo, L. , Filho, S. V. and Lopes, L. R. (2014) Endoplasmic reticulum stress and Nox-mediated reactive oxygen species signaling in the peripheral vasculature : potential role in hypertension. Antioxidants and Redox Signaling, 20(1), pp. 121-134. (doi: 10.1089/ars.2013.5262) (PMID:23472786) (PMCID:PMC3880927)

De Lucca Camargo, L. , Babelova, A., Mieth, A., Weigert, A., Mooz, J., Rajalingam, K., Heide, H., Wittig, I., Rossetti Lopes, L. and Brandes, R. P. (2013) Endo-PDI is required for TNFα-induced angiogenesis. Free Radical Biology and Medicine, 65, pp. 1398-1407. (doi: 10.1016/j.freeradbiomed.2013.09.028) (PMID:24103565)

Chignalia, A. Z. et al. (2012) Testosterone induces vascular smooth muscle cell migration by NADPH oxidase and c-Src-dependent pathways. Hypertension, 59(6), pp. 1263-1271. (doi: 10.1161/HYPERTENSIONAHA.111.180620) (PMID:22566500)

Denadai-Souza, A., De Lucca Camargo, L. , Ribela, M. T.C.P., Keeble, J. E., Costa, S. K.P. and Muscará, M. N. (2012) Participation of peripheral tachykinin NK1 receptors in the carrageenan-induced inflammation of the rat temporomandibular joint. European journal of pain, 13, pp. 812-819. (doi: 10.1016/j.ejpain.2008.09.012) (PMID:18976941)

Book Sections

de Lucca Camargo, L. and Touyz, R. M. (2019) Reactive oxygen species. In: Touyz, R. M. and Delles, C. (eds.) Textbook of Vascular Medicine. Springer: Cham, pp. 127-136. ISBN 9783030164805 (doi: 10.1007/978-3-030-16481-2_12)