Professor David Harrison
- Visiting Professor (School of Cardiovascular & Metabolic Health)
Publications
2023
Touyz, R. M. and Harrison, D. G. (2023) Hope for resistant hypertension through BrigHTN and PRECISION. Nature Reviews Nephrology, 19(4), pp. 216-217. (doi: 10.1038/s41581-023-00676-2) (PMID:36658403)
2022
Szczepaniak, P. et al. (2022) Breast cancer chemotherapy induces vascular dysfunction and hypertension through NOX4 dependent mechanism. Journal of Clinical Investigation, 132(13), e149117. (doi: 10.1172/JCI149117) (PMID:35617030) (PMCID:PMC9246378)
2020
Madhur, M. S., Kirabo, A., Guzik, T. J. and Harrison, D. (2020) From rags to riches. Hypertension, 75(4), pp. 930-934. (doi: 10.1161/hypertensionaha.119.14612) (PMID:32078385)
2019
Czesnikiewicz-Guzik, M. , Nosalski, R., Mikolajczyk, T. P., Vidler, F., Dohnal, T., Dembowska, E., Graham, D. , Harrison, D. G. and Guzik, T. J. (2019) Th1 type immune responses to Porphyromonas gingivalis antigens exacerbate angiotensin II dependent hypertension and vascular dysfunction. British Journal of Pharmacology, 176(12), pp. 1922-1931. (doi: 10.1111/bph.14536) (PMID:30414380) (PMCID:PMC6534780)
2018
Guzik, T. J. et al. (2018) What matters in Cardiovascular Research? Scientific discovery driving clinical delivery. Cardiovascular Research, 114(12), pp. 1565-1568. (doi: 10.1093/cvr/cvy214)
Loperena, R. et al. (2018) Hypertension and increased endothelial mechanical stretch promote monocyte differentiation and activation: roles of STAT3, interleukin 6 and hydrogen peroxide. Cardiovascular Research, 114(11), pp. 1547-1563. (doi: 10.1093/cvr/cvy112) (PMID:29800237) (PMCID:PMC6106108)
2017
Guzik, T. J., Skiba, D. S., Touyz, R. M. and Harrison, D. G. (2017) The role of infiltrating immune cells in dysfunctional adipose tissue. Cardiovascular Research, 113(9), pp. 1009-1023. (doi: 10.1093/cvr/cvx108) (PMID:28838042) (PMCID:PMC5852626)
2016
Griendling, K. K., Touyz, R. M. , Zweier, J. L., Dikalov, S., Chilian, W., Yeong-Renn, C., Harrison, D. G. and Bhatnagar, A. (2016) Measurement of reactive oxygen species, reactive nitrogen species, and redox-dependent signaling in the cardiovascular system: a scientific statement from the American heart association. Circulation Research, 119(5), e39-e75. (doi: 10.1161/RES.0000000000000110) (PMID:27418630) (PMCID:PMC5446086)
2014
Wolkow, P. P. et al. (2014) GTP cyclohydrolase I gene polymorphisms are associated with endothelial dysfunction and oxidative stress in patients with type 2 diabetes mellitus. PLoS ONE, 9(11), e108587. (doi: 10.1371/journal.pone.0108587) (PMID:25369080) (PMCID:PMC4219671)
2007
Guzik, T. J. and Harrison, D. G. (2007) Endothelial NF-κB as a mediator of kidney damage: the missing link between systemic vascular and renal disease? Circulation Research, 101(3), pp. 227-229. (doi: 10.1161/CIRCRESAHA.107.158295) (PMID:17673681)
Widder, J. D., Guzik, T. J., Mueller, C. F.H., Clempus, R. E., Schmidt, H. H.H.W., Dikalov, S. I., Griendling, K. K., Jones, D. P. and Harrison, D. G. (2007) Role of the multidrug resistance protein-1 in hypertension and vascular dysfunction caused by angiotensin II. Arteriosclerosis, Thrombosis, and Vascular Biology, 27(4), pp. 762-768. (doi: 10.1161/01.ATV.0000259298.11129.a2) (PMID:17272743)
Harrison, D. G., Gongora, M. C., Guzik, T. J. and Widder, J. (2007) Oxidative stress and hypertension. Journal of the American Society of Hypertension, 1(1), pp. 30-44. (doi: 10.1016/j.jash.2006.11.006) (PMID:20409831)
2006
Guzik, T. J. and Harrison, D. G. (2006) Vascular NADPH oxidases as drug targets for novel antioxidant strategies. Drug Discovery Today, 11(11-12), pp. 524-533. (doi: 10.1016/j.drudis.2006.04.003) (PMID:16713904)
Guzik, T. J., Sadowski, J., Guzik, B., Jopek, A., Kapelak, B., Przybyłowski, P., Wierzbicki, K., Korbut, R., Harrison, D. G. and Channon, K. M. (2006) Coronary artery superoxide production and nox isoform expression in human coronary artery disease. Arteriosclerosis, Thrombosis, and Vascular Biology, 26(2), pp. 333-339. (doi: 10.1161/01.ATV.0000196651.64776.51) (PMID:16293794)
Articles
Touyz, R. M. and Harrison, D. G. (2023) Hope for resistant hypertension through BrigHTN and PRECISION. Nature Reviews Nephrology, 19(4), pp. 216-217. (doi: 10.1038/s41581-023-00676-2) (PMID:36658403)
Szczepaniak, P. et al. (2022) Breast cancer chemotherapy induces vascular dysfunction and hypertension through NOX4 dependent mechanism. Journal of Clinical Investigation, 132(13), e149117. (doi: 10.1172/JCI149117) (PMID:35617030) (PMCID:PMC9246378)
Madhur, M. S., Kirabo, A., Guzik, T. J. and Harrison, D. (2020) From rags to riches. Hypertension, 75(4), pp. 930-934. (doi: 10.1161/hypertensionaha.119.14612) (PMID:32078385)
Czesnikiewicz-Guzik, M. , Nosalski, R., Mikolajczyk, T. P., Vidler, F., Dohnal, T., Dembowska, E., Graham, D. , Harrison, D. G. and Guzik, T. J. (2019) Th1 type immune responses to Porphyromonas gingivalis antigens exacerbate angiotensin II dependent hypertension and vascular dysfunction. British Journal of Pharmacology, 176(12), pp. 1922-1931. (doi: 10.1111/bph.14536) (PMID:30414380) (PMCID:PMC6534780)
Guzik, T. J. et al. (2018) What matters in Cardiovascular Research? Scientific discovery driving clinical delivery. Cardiovascular Research, 114(12), pp. 1565-1568. (doi: 10.1093/cvr/cvy214)
Loperena, R. et al. (2018) Hypertension and increased endothelial mechanical stretch promote monocyte differentiation and activation: roles of STAT3, interleukin 6 and hydrogen peroxide. Cardiovascular Research, 114(11), pp. 1547-1563. (doi: 10.1093/cvr/cvy112) (PMID:29800237) (PMCID:PMC6106108)
Guzik, T. J., Skiba, D. S., Touyz, R. M. and Harrison, D. G. (2017) The role of infiltrating immune cells in dysfunctional adipose tissue. Cardiovascular Research, 113(9), pp. 1009-1023. (doi: 10.1093/cvr/cvx108) (PMID:28838042) (PMCID:PMC5852626)
Griendling, K. K., Touyz, R. M. , Zweier, J. L., Dikalov, S., Chilian, W., Yeong-Renn, C., Harrison, D. G. and Bhatnagar, A. (2016) Measurement of reactive oxygen species, reactive nitrogen species, and redox-dependent signaling in the cardiovascular system: a scientific statement from the American heart association. Circulation Research, 119(5), e39-e75. (doi: 10.1161/RES.0000000000000110) (PMID:27418630) (PMCID:PMC5446086)
Wolkow, P. P. et al. (2014) GTP cyclohydrolase I gene polymorphisms are associated with endothelial dysfunction and oxidative stress in patients with type 2 diabetes mellitus. PLoS ONE, 9(11), e108587. (doi: 10.1371/journal.pone.0108587) (PMID:25369080) (PMCID:PMC4219671)
Guzik, T. J. and Harrison, D. G. (2007) Endothelial NF-κB as a mediator of kidney damage: the missing link between systemic vascular and renal disease? Circulation Research, 101(3), pp. 227-229. (doi: 10.1161/CIRCRESAHA.107.158295) (PMID:17673681)
Widder, J. D., Guzik, T. J., Mueller, C. F.H., Clempus, R. E., Schmidt, H. H.H.W., Dikalov, S. I., Griendling, K. K., Jones, D. P. and Harrison, D. G. (2007) Role of the multidrug resistance protein-1 in hypertension and vascular dysfunction caused by angiotensin II. Arteriosclerosis, Thrombosis, and Vascular Biology, 27(4), pp. 762-768. (doi: 10.1161/01.ATV.0000259298.11129.a2) (PMID:17272743)
Harrison, D. G., Gongora, M. C., Guzik, T. J. and Widder, J. (2007) Oxidative stress and hypertension. Journal of the American Society of Hypertension, 1(1), pp. 30-44. (doi: 10.1016/j.jash.2006.11.006) (PMID:20409831)
Guzik, T. J. and Harrison, D. G. (2006) Vascular NADPH oxidases as drug targets for novel antioxidant strategies. Drug Discovery Today, 11(11-12), pp. 524-533. (doi: 10.1016/j.drudis.2006.04.003) (PMID:16713904)
Guzik, T. J., Sadowski, J., Guzik, B., Jopek, A., Kapelak, B., Przybyłowski, P., Wierzbicki, K., Korbut, R., Harrison, D. G. and Channon, K. M. (2006) Coronary artery superoxide production and nox isoform expression in human coronary artery disease. Arteriosclerosis, Thrombosis, and Vascular Biology, 26(2), pp. 333-339. (doi: 10.1161/01.ATV.0000196651.64776.51) (PMID:16293794)