Dr Tomasz Mikolajczyk
- Affiliate (School of Cardiovascular & Metabolic Health)
Publications
2022
Szczepaniak, P. et al. (2022) Breast cancer chemotherapy induces vascular dysfunction and hypertension through NOX4 dependent mechanism. Journal of Clinical Investigation, 132(13), e149117. (doi: 10.1172/JCI149117) (PMID:35617030) (PMCID:PMC9246378)
2021
Szczepaniak, P., Mikołajczyk, T. P., Cześnikiewicz-Guzik, M. and Guzik, T. J. (2021) Periodontitis as an inflammatory trigger in hypertension: from basic immunology to clinical implications. Kardiologia Polska, 79(11), pp. 1206-1214. (doi: 10.33963/KP.a2021.0161) (PMID:34847238)
Konior-Rozlachowska, A., Siedlinski, M., Szczepaniak, P., Nosalski, R., Murray, E. and Mikolajczyk, T.P. (2021) Systemic and vascular inflammation in experimental allergic asthma. Journal of Physiology and Pharmacology, 72(2), (doi: 10.26402/jpp.2021.2.03) (PMID:34374654)
Mikolajczyk, T. P., Szczepaniak, P., Vidler, F., Maffia, P. , Graham, G. J. and Guzik, T. J. (2021) Role of inflammatory chemokines in hypertension. Pharmacology and Therapeutics, 223, 107799. (doi: 10.1016/j.pharmthera.2020.107799) (PMID:33359600)
2020
Nosalski, R., Mikolajczyk, T., Siedlinski, M., Saju, B., Koziol, J., Maffia, P. and Guzik, T.J. (2020) Nox1/4 inhibition exacerbates age dependent perivascular inflammation and fibrosis in a model of spontaneous hypertension. Pharmacological Research, 161, 105235. (doi: 10.1016/j.phrs.2020.105235) (PMID:33131726) (PMCID:PMC8316606)
Luc, K., Schramm-Luc, A., Guzik, T.J. and Mikolajczyk, T.P. (2020) Oxidative stress and inflammatory markers in prediabetes and diabetes. Journal of Physiology and Pharmacology, 70(6), pp. 809-824. (doi: 10.26402/jpp.2019.6.01) (PMID:32084643)
2019
Czesnikiewicz-Guzik, M. et al. (2019) Causal association between periodontitis and hypertension: evidence from Mendelian randomization and a randomized controlled trial of non-surgical periodontal therapy. European Heart Journal, 40(42), pp. 3459-3470. (doi: 10.1093/eurheartj/ehz646) (PMID:31504461) (PMCID:PMC6837161)
Sagan, A. et al. (2019) T cells are dominant population in human abdominal aortic aneurysms and their infiltration in the perivascular tissue correlates with disease severity. Frontiers in Immunology, 10, 1979. (doi: 10.3389/fimmu.2019.01979) (PMID:31552015) (PMCID:PMC6736986)
Czesnikiewicz-Guzik, M. , Nosalski, R., Mikolajczyk, T. P., Vidler, F., Dohnal, T., Dembowska, E., Graham, D. , Harrison, D. G. and Guzik, T. J. (2019) Th1 type immune responses to Porphyromonas gingivalis antigens exacerbate angiotensin II dependent hypertension and vascular dysfunction. British Journal of Pharmacology, 176(12), pp. 1922-1931. (doi: 10.1111/bph.14536) (PMID:30414380) (PMCID:PMC6534780)
Mikolajczyk, T. P. et al. (2019) 1,2,3,4,6 penta-O -galloyl-β-D-glucose modulates perivascular inflammation and prevents vascular dysfunction in angiotensin II-induced hypertension. British Journal of Pharmacology, 176(12), pp. 1951-1965. (doi: 10.1111/bph.14583) (PMID:30658013) (PMCID:PMC6534792)
Batko, B., Schramm-Luc, A., Skiba, D. S., Mikolajczyk, T. P. and Siedlinski, M. (2019) TNF-α inhibitors decrease classical CD14hiCD16− monocyte subsets in highly active, conventional treatment refractory rheumatoid arthritis and ankylosing spondylitis. International Journal of Molecular Sciences, 20(2), 291. (doi: 10.3390/ijms20020291) (PMID:30642076) (PMCID:PMC6358965)
2018
Batko, B. et al. (2018) Microvascular dysfunction in ankylosing spondylitis is associated with disease activity and is improved by anti-TNF treatment. Scientific Reports, 8, 13205. (doi: 10.1038/s41598-018-31550-y) (PMID:30181568) (PMCID:PMC6123474)
Loperena, R. et al. (2018) Hypertension and increased endothelial mechanical stretch promote monocyte differentiation and activation: roles of STAT3, interleukin 6 and hydrogen peroxide. Cardiovascular Research, 114(11), pp. 1547-1563. (doi: 10.1093/cvr/cvy112) (PMID:29800237) (PMCID:PMC6106108)
2017
Skiba, D.S. et al. (2017) Anti‐atherosclerotic effect of the angiotensin 1–7 mimetic AVE0991 is mediated by inhibition of perivascular and plaque inflammation in early atherosclerosis. British Journal of Pharmacology, 174(22), pp. 4055-4069. (doi: 10.1111/bph.13685) (PMID:27935022) (PMCID:PMC5659999)
Maciag, J., Mikolajczyk, T., Matusik, P., Nowakowski, D., Robertson, D. , Maciag, A., Osmenda, G. and Czesnikiewicz-Guzik, M. (2017) The effect of the treatment of denture related stomatitis on peripheral T cells and monocytes. Oral Health and Preventive Dentistry, 15(3), pp. 259-268. (doi: 10.3290/j.ohpd.a38527) (PMID:28674706)
Siedlinski, M. et al. (2017) Vascular transcriptome profiling identifies Sphingosine kinase 1 as a modulator of angiotensin II-induced vascular dysfunction. Scientific Reports, 7, 44131. (doi: 10.1038/srep44131) (PMID:28276483) (PMCID:PMC5343497)
2016
Schramm, A. et al. (2016) Th17 responses are not altered by natural exposure to seasonal allergens in pollen-sensitive patients. Allergy, Asthma and Clinical Immunology, 12(1), 55. (doi: 10.1186/s13223-016-0157-6) (PMID:27799958) (PMCID:PMC5078933)
Urbanski, K., Filip, G., Filip, M., Ludew, D., Szczepaniak, P., Nosalski, R.,, Sagan, A., Mikolajczyk, T., Kapelak, B. and Guzik, T.J. (2016) [OP.2D.04] Perivascular T regulatory cells and endothelial dysfunction in human atherosclerosis. Journal of Hypertension, 34(S2), e24-e25. (doi: 10.1097/01.hjh.0000491394.17973.0a) (PMID:27508639)
Mikolajczyk, T.P. et al. (2016) Role of chemokine RANTES in the regulation of perivascular inflammation, T-cell accumulation, and vascular dysfunction in hypertension. FASEB Journal, 30(5), pp. 1987-1999. (doi: 10.1096/fj.201500088R) (PMID:26873938) (PMCID:PMC4836375)
Maga, P., Mikolajczyk, T., Partyka, L., Krzanowski, M., Malinowski, K. P. and Nizankowski, R. (2016) Percutaneous transluminal angioplasty in patients with peripheral arterial disease does not affect circulating monocyte subpopulations. BioMed Research International, 2016, 2708957. (doi: 10.1155/2016/2708957) (PMID:27818999) (PMCID:PMC5081453)
Articles
Szczepaniak, P. et al. (2022) Breast cancer chemotherapy induces vascular dysfunction and hypertension through NOX4 dependent mechanism. Journal of Clinical Investigation, 132(13), e149117. (doi: 10.1172/JCI149117) (PMID:35617030) (PMCID:PMC9246378)
Szczepaniak, P., Mikołajczyk, T. P., Cześnikiewicz-Guzik, M. and Guzik, T. J. (2021) Periodontitis as an inflammatory trigger in hypertension: from basic immunology to clinical implications. Kardiologia Polska, 79(11), pp. 1206-1214. (doi: 10.33963/KP.a2021.0161) (PMID:34847238)
Konior-Rozlachowska, A., Siedlinski, M., Szczepaniak, P., Nosalski, R., Murray, E. and Mikolajczyk, T.P. (2021) Systemic and vascular inflammation in experimental allergic asthma. Journal of Physiology and Pharmacology, 72(2), (doi: 10.26402/jpp.2021.2.03) (PMID:34374654)
Mikolajczyk, T. P., Szczepaniak, P., Vidler, F., Maffia, P. , Graham, G. J. and Guzik, T. J. (2021) Role of inflammatory chemokines in hypertension. Pharmacology and Therapeutics, 223, 107799. (doi: 10.1016/j.pharmthera.2020.107799) (PMID:33359600)
Nosalski, R., Mikolajczyk, T., Siedlinski, M., Saju, B., Koziol, J., Maffia, P. and Guzik, T.J. (2020) Nox1/4 inhibition exacerbates age dependent perivascular inflammation and fibrosis in a model of spontaneous hypertension. Pharmacological Research, 161, 105235. (doi: 10.1016/j.phrs.2020.105235) (PMID:33131726) (PMCID:PMC8316606)
Luc, K., Schramm-Luc, A., Guzik, T.J. and Mikolajczyk, T.P. (2020) Oxidative stress and inflammatory markers in prediabetes and diabetes. Journal of Physiology and Pharmacology, 70(6), pp. 809-824. (doi: 10.26402/jpp.2019.6.01) (PMID:32084643)
Czesnikiewicz-Guzik, M. et al. (2019) Causal association between periodontitis and hypertension: evidence from Mendelian randomization and a randomized controlled trial of non-surgical periodontal therapy. European Heart Journal, 40(42), pp. 3459-3470. (doi: 10.1093/eurheartj/ehz646) (PMID:31504461) (PMCID:PMC6837161)
Sagan, A. et al. (2019) T cells are dominant population in human abdominal aortic aneurysms and their infiltration in the perivascular tissue correlates with disease severity. Frontiers in Immunology, 10, 1979. (doi: 10.3389/fimmu.2019.01979) (PMID:31552015) (PMCID:PMC6736986)
Czesnikiewicz-Guzik, M. , Nosalski, R., Mikolajczyk, T. P., Vidler, F., Dohnal, T., Dembowska, E., Graham, D. , Harrison, D. G. and Guzik, T. J. (2019) Th1 type immune responses to Porphyromonas gingivalis antigens exacerbate angiotensin II dependent hypertension and vascular dysfunction. British Journal of Pharmacology, 176(12), pp. 1922-1931. (doi: 10.1111/bph.14536) (PMID:30414380) (PMCID:PMC6534780)
Mikolajczyk, T. P. et al. (2019) 1,2,3,4,6 penta-O -galloyl-β-D-glucose modulates perivascular inflammation and prevents vascular dysfunction in angiotensin II-induced hypertension. British Journal of Pharmacology, 176(12), pp. 1951-1965. (doi: 10.1111/bph.14583) (PMID:30658013) (PMCID:PMC6534792)
Batko, B., Schramm-Luc, A., Skiba, D. S., Mikolajczyk, T. P. and Siedlinski, M. (2019) TNF-α inhibitors decrease classical CD14hiCD16− monocyte subsets in highly active, conventional treatment refractory rheumatoid arthritis and ankylosing spondylitis. International Journal of Molecular Sciences, 20(2), 291. (doi: 10.3390/ijms20020291) (PMID:30642076) (PMCID:PMC6358965)
Batko, B. et al. (2018) Microvascular dysfunction in ankylosing spondylitis is associated with disease activity and is improved by anti-TNF treatment. Scientific Reports, 8, 13205. (doi: 10.1038/s41598-018-31550-y) (PMID:30181568) (PMCID:PMC6123474)
Loperena, R. et al. (2018) Hypertension and increased endothelial mechanical stretch promote monocyte differentiation and activation: roles of STAT3, interleukin 6 and hydrogen peroxide. Cardiovascular Research, 114(11), pp. 1547-1563. (doi: 10.1093/cvr/cvy112) (PMID:29800237) (PMCID:PMC6106108)
Skiba, D.S. et al. (2017) Anti‐atherosclerotic effect of the angiotensin 1–7 mimetic AVE0991 is mediated by inhibition of perivascular and plaque inflammation in early atherosclerosis. British Journal of Pharmacology, 174(22), pp. 4055-4069. (doi: 10.1111/bph.13685) (PMID:27935022) (PMCID:PMC5659999)
Maciag, J., Mikolajczyk, T., Matusik, P., Nowakowski, D., Robertson, D. , Maciag, A., Osmenda, G. and Czesnikiewicz-Guzik, M. (2017) The effect of the treatment of denture related stomatitis on peripheral T cells and monocytes. Oral Health and Preventive Dentistry, 15(3), pp. 259-268. (doi: 10.3290/j.ohpd.a38527) (PMID:28674706)
Siedlinski, M. et al. (2017) Vascular transcriptome profiling identifies Sphingosine kinase 1 as a modulator of angiotensin II-induced vascular dysfunction. Scientific Reports, 7, 44131. (doi: 10.1038/srep44131) (PMID:28276483) (PMCID:PMC5343497)
Schramm, A. et al. (2016) Th17 responses are not altered by natural exposure to seasonal allergens in pollen-sensitive patients. Allergy, Asthma and Clinical Immunology, 12(1), 55. (doi: 10.1186/s13223-016-0157-6) (PMID:27799958) (PMCID:PMC5078933)
Urbanski, K., Filip, G., Filip, M., Ludew, D., Szczepaniak, P., Nosalski, R.,, Sagan, A., Mikolajczyk, T., Kapelak, B. and Guzik, T.J. (2016) [OP.2D.04] Perivascular T regulatory cells and endothelial dysfunction in human atherosclerosis. Journal of Hypertension, 34(S2), e24-e25. (doi: 10.1097/01.hjh.0000491394.17973.0a) (PMID:27508639)
Mikolajczyk, T.P. et al. (2016) Role of chemokine RANTES in the regulation of perivascular inflammation, T-cell accumulation, and vascular dysfunction in hypertension. FASEB Journal, 30(5), pp. 1987-1999. (doi: 10.1096/fj.201500088R) (PMID:26873938) (PMCID:PMC4836375)
Maga, P., Mikolajczyk, T., Partyka, L., Krzanowski, M., Malinowski, K. P. and Nizankowski, R. (2016) Percutaneous transluminal angioplasty in patients with peripheral arterial disease does not affect circulating monocyte subpopulations. BioMed Research International, 2016, 2708957. (doi: 10.1155/2016/2708957) (PMID:27818999) (PMCID:PMC5081453)