Dr Cristiano Spadaccio
- Honorary Clinical Lecturer (School of Cardiovascular & Metabolic Health)
Publications
2022
Spadaccio, C., Nenna, A., Rose, D., Piccirillo, F., Nusca, A., Grigioni, F., Chello, M. and Vlahakes, G. J. (2022) The role of angiogenesis and arteriogenesis in myocardial infarction and coronary revascularization. Journal of Cardiovascular Translational Research, 15(5), pp. 1024-1048. (doi: 10.1007/s12265-022-10241-0) (PMID:35357670)
Klepper, M., Noirhomme, P., de Kerchove, L., Mastrobuoni, S., Spadaccio, C., Lemaire, G., El Khoury, G. and Navarra, E. (2022) Robotic mitral valve repair: A single center experience over a 7‐year period. Journal of Cardiac Surgery, 37(8), pp. 2266-2277. (doi: 10.1111/jocs.16575) (PMID:35510407)
Creber, R. M., Dimagli, A., Spadaccio, C., Myers, A., Moscarelli, M., Demetres, M., Little, M., Fremes, S. and Gaudino, M. (2022) Effect of coronary artery bypass grafting on quality of life: a meta-analysis of randomized trials. European Heart Journal: Quality of Care and Clinical Outcomes, 8(3), pp. 259-268. (doi: 10.1093/ehjqcco/qcab075) (PMID:34643672)
2021
Nappi, F., Mazzocchi, L., Spadaccio, C., Attias, D., Timofeva, I., Macron, L., Iervolino, A., Morganti, S. and Auricchio, F. (2021) CoreValve vs. Sapien 3 transcatheter aortic valve replacement: a finite element analysis study. Bioengineering, 8(5), 52. (doi: 10.3390/bioengineering8050052) (PMID:33925437) (PMCID:PMC8146716)
Vinciguerra, M., Grigioni, F., Romiti, S., Benfari, G., Rose, D., Spadaccio, C., Cimino, S., De Bellis, A. and Greco, E. (2021) Ischemic mitral regurgitation: a multifaceted syndrome with evolving therapies. Biomedicines, 9(5), 447. (doi: 10.3390/biomedicines9050447) (PMID:33919263) (PMCID:PMC8143318)
2020
Spadaccio, C., Mazzocchi, L., Timofeva, I., Macron, L., De Cecco, C. N., Morganti, S., Auricchio, F. and Nappi, F. (2020) Bioengineering case study to evaluate complications of adverse anatomy of aortic root in transcatheter aortic valve replacement: combining biomechanical modelling with CT imaging. Bioengineering, 7(4), 121. (doi: 10.3390/bioengineering7040121) (PMID:33019739) (PMCID:PMC7712517)
Nappi, F., Singh, S. S. A., Nappi, P., Spadaccio, C., Nenna, A., Gentile, F. and Chello, M. (2020) Heart valve endocarditis. Surgical Technology International, 37, pp. 203-215. (PMID:32520388)
Spadaccio, C. et al. (2020) Thoracic aortic surgery: status and upcoming novelties. Minerva Cardioangiologica, 68(5), pp. 518-531. (doi: 10.23736/S0026-4725.20.05263-9) (PMID:32319269)
Gaudino, M., Arvind, V., Hameed, I., Di Franco, A., Spadaccio, C., Bhatt, D. L. and Bagiella, E. (2020) Effects of the COVID-19 pandemic on active non-COVID clinical trials. Journal of the American College of Cardiology, 76(13), pp. 1605-1606. (doi: 10.1016/j.jacc.2020.07.051) (PMID:32745501)
Nappi, F., Avtaar Singh, S. S., Spadaccio, C. and Acar, C. (2020) Ross operation 23 years after surgery: it should not be a “forgotten” option. Journal of Cardiac Surgery, 35(4), pp. 952-956. (doi: 10.1111/jocs.14489) (PMID:32115768)
Nappi, F., Spadaccio, C., Acar, C. and El-Hamamsy, I. (2020) Lights and shadows on the Ross procedure: biological solutions for biological problems. Seminars in Thoracic and Cardiovascular Surgery, 32(4), pp. 815-822. (doi: 10.1053/j.semtcvs.2020.04.006) (PMID:32439545)
2018
Nappi, F., Nenna, A., Petitti, T., Spadaccio, C., Gambardella, I., Lusini, M., Chello, M. and Acar, C. (2018) Long-term outcome of cryopreserved allograft for aortic valve replacement. Journal of Thoracic and Cardiovascular Surgery, 156(4), 1357-1365.e6. (doi: 10.1016/j.jtcvs.2018.04.040) (PMID:29759737)
Fraldi, M., Spadaccio, C., Acar, C. and Nappi, F. (2018) Best to clarify to avoid misunderstandings in the biomechanics of Ross Operation: parentheses matter. Annals of Thoracic Surgery, 106(2), pp. 641-642. (doi: 10.1016/j.athoracsur.2018.01.047) (PMID:29477565)
Nappi, F., Nenna, A., Larobina, D., Carotenuto, A. R., Jarraya, M., Spadaccio, C., Fraldi, M., Chello, M., Acar, C. and Carrel, T. (2018) Simulating the ideal geometrical and biomechanical parameters of the pulmonary autograft to prevent failure in the Ross operation. Interactive Cardiovascular and Thoracic Surgery, 27(2), pp. 269-276. (doi: 10.1093/icvts/ivy070) (PMID:29538653)
Spadaccio, C., Dalby, M. and Danton, M. H.D. (2018) Daytime variations in perioperative myocardial injury. Lancet, 391(10135), pp. 2105-2106. (doi: 10.1016/S0140-6736(18)30785-2) (PMID:29856342)
Nappi, F., Spadaccio, C., Mihos, C. G. and Fraldi, M. (2018) Euler's elastica-based biomechanical assessment for neochordal insertion in the treatment of degenerative mitral valve repair. Journal of Thoracic and Cardiovascular Surgery, 155(2), pp. 603-605. (doi: 10.1016/j.jtcvs.2017.09.002) (PMID:29415386)
2017
Avtaar Singh, S. S., Das De, S., Spadaccio, C., Berry, C. and Al-Attar, N. (2017) An overview of different methods of myocardial protection currently employed peri-transplantation. Vessel Plus, 1, pp. 213-229. (doi: 10.20517/2574-1209.2017.26)
Nappi, F., Spadaccio, C. and Sablayrolles, J.-L. (2017) Delayed prosthesis malposition after transcatheter aortic valve implantation causing coronaries obstruction. European Journal of Cardio-Thoracic Surgery, 52(6), pp. 1227-1228. (doi: 10.1093/ejcts/ezx266) (PMID:28950358)
Nappi, F. and Spadaccio, C. (2017) Simplest solutions are not always the cleverest: can we stitch in an infected annulus? Should we rethink the current guidelines? Journal of Thoracic and Cardiovascular Surgery, 154(6), pp. 1899-1900. (doi: 10.1016/j.jtcvs.2017.05.099) (PMID:29132883)
Spadaccio, C., Elkasrawy, K. and Sutherland, F. W.H. (2017) New minimally invasive surgical approach for excision of left atrial myxoma. General Thoracic and Cardiovascular Surgery, 65(10), pp. 605-608. (doi: 10.1007/s11748-017-0779-8) (PMID:28493094)
Nappi, F. and Spadaccio, C. (2017) Biomechanics of failed ischemic mitral valve repair: discovering new frontiers. Journal of Thoracic and Cardiovascular Surgery, 154(3), pp. 832-833. (doi: 10.1016/j.jtcvs.2017.04.035) (PMID:28826151)
Fraldi, M., Spadaccio, C., Mihos, C. G. and Nappi, F. (2017) Analysing the reasons of failure of surgical mitral repair approaches-do we need to better think in biomechanics? Journal of Thoracic Disease, 9(S7), S661-S664. (doi: 10.21037/jtd.2017.06.33) (PMID:28740720) (PMCID:PMC5505944)
Nappi, F., Spadaccio, C., Chello, M. and Mihos, C. G. (2017) Papillary muscle approximation in mitral valve repair for secondary MR. Journal of Thoracic Disease, 9(S7), S635-S639. (doi: 10.21037/jtd.2017.06.98) (PMID:28740718) (PMCID:PMC5505932)
Nappi, F., Spadaccio, C., Mihos, C. G. and Fraldi, M. (2017) Biomechanics raises solution to avoid geometric mitral valve configuration abnormalities in ischemic mitral regurgitation. Journal of Thoracic Disease, 9(S7), S624-S628. (doi: 10.21037/jtd.2017.05.63) (PMID:28740716) (PMCID:PMC5505935)
Nappi, F., Spadaccio, C. and Acar, C. (2017) Use of allogeneic tissue to treat infective valvular disease: Has everything been said? Journal of Thoracic and Cardiovascular Surgery, 153(4), pp. 824-828. (doi: 10.1016/j.jtcvs.2016.09.071) (PMID:27866779)
Spadaccio, C. et al. (2017) Implantation of a poly-L-lactide GCSF-functionalized scaffold in a model of chronic myocardial infarction. Journal of Cardiovascular Translational Research, 10(1), pp. 47-65. (doi: 10.1007/s12265-016-9718-9) (PMID:28116550) (PMCID:PMC5323505)
Spadaccio, C., Nappi, F., Al-Attar, N., Coccia, R., Perluigi, M. and Di Domenico, F. (2017) Introductory editorial: drug-eluting stents or drug-eluting grafts? Insights from proteomic analysis. Drug Target Insights, 10(S1), pp. 15-19. (doi: 10.4137/DTI.S41240) (PMID:28096649) (PMCID:PMC5215111)
Spadaccio, C., Nappi, F., Sablayrolles, J.-L. and Sutherland, F. W.H. (2017) TAVR vs SAVR: rising expectations and changing indications for surgery in response to PARTNER II. Seminars in Thoracic and Cardiovascular Surgery, 29(1), pp. 8-11. (doi: 10.1053/j.semtcvs.2017.01.008) (PMID:28684004)
2016
Nappi, F., Spadaccio, C. and Sablayrolles, J. L. (2016) Pushing the limits in transcatheter aortic valve replacement: high-volume center's effect, overconfidence, or something else? JACC: Cardiovascular Interventions, 9(21), pp. 2186-2188. (doi: 10.1016/j.jcin.2016.08.014) (PMID:27744044)
Nappi, F. and Spadaccio, C. (2016) Coronary artery bypass grafting (CABG) alone in moderate ischemic mitral regurgitation: is CABG really enough? Annals of Translational Medicine, 4(20), 413. (doi: 10.21037/atm.2016.08.47) (PMID:27867965) (PMCID:PMC5107413)
Spadaccio, C., Nappi, F., Al-Attar, N., Sutherland, F. W., Acar, C., Nenna, A., Trombetta, M., Chello, M. and Rainer, A. (2016) Old myths, new concerns: the long-term effects of ascending aorta replacement with Dacron grafts. Not all that glitters is gold. Journal of Cardiovascular Translational Research, 9(4), pp. 334-342. (doi: 10.1007/s12265-016-9699-8) (PMID:27245785)
Articles
Spadaccio, C., Nenna, A., Rose, D., Piccirillo, F., Nusca, A., Grigioni, F., Chello, M. and Vlahakes, G. J. (2022) The role of angiogenesis and arteriogenesis in myocardial infarction and coronary revascularization. Journal of Cardiovascular Translational Research, 15(5), pp. 1024-1048. (doi: 10.1007/s12265-022-10241-0) (PMID:35357670)
Klepper, M., Noirhomme, P., de Kerchove, L., Mastrobuoni, S., Spadaccio, C., Lemaire, G., El Khoury, G. and Navarra, E. (2022) Robotic mitral valve repair: A single center experience over a 7‐year period. Journal of Cardiac Surgery, 37(8), pp. 2266-2277. (doi: 10.1111/jocs.16575) (PMID:35510407)
Creber, R. M., Dimagli, A., Spadaccio, C., Myers, A., Moscarelli, M., Demetres, M., Little, M., Fremes, S. and Gaudino, M. (2022) Effect of coronary artery bypass grafting on quality of life: a meta-analysis of randomized trials. European Heart Journal: Quality of Care and Clinical Outcomes, 8(3), pp. 259-268. (doi: 10.1093/ehjqcco/qcab075) (PMID:34643672)
Nappi, F., Mazzocchi, L., Spadaccio, C., Attias, D., Timofeva, I., Macron, L., Iervolino, A., Morganti, S. and Auricchio, F. (2021) CoreValve vs. Sapien 3 transcatheter aortic valve replacement: a finite element analysis study. Bioengineering, 8(5), 52. (doi: 10.3390/bioengineering8050052) (PMID:33925437) (PMCID:PMC8146716)
Vinciguerra, M., Grigioni, F., Romiti, S., Benfari, G., Rose, D., Spadaccio, C., Cimino, S., De Bellis, A. and Greco, E. (2021) Ischemic mitral regurgitation: a multifaceted syndrome with evolving therapies. Biomedicines, 9(5), 447. (doi: 10.3390/biomedicines9050447) (PMID:33919263) (PMCID:PMC8143318)
Spadaccio, C., Mazzocchi, L., Timofeva, I., Macron, L., De Cecco, C. N., Morganti, S., Auricchio, F. and Nappi, F. (2020) Bioengineering case study to evaluate complications of adverse anatomy of aortic root in transcatheter aortic valve replacement: combining biomechanical modelling with CT imaging. Bioengineering, 7(4), 121. (doi: 10.3390/bioengineering7040121) (PMID:33019739) (PMCID:PMC7712517)
Nappi, F., Singh, S. S. A., Nappi, P., Spadaccio, C., Nenna, A., Gentile, F. and Chello, M. (2020) Heart valve endocarditis. Surgical Technology International, 37, pp. 203-215. (PMID:32520388)
Spadaccio, C. et al. (2020) Thoracic aortic surgery: status and upcoming novelties. Minerva Cardioangiologica, 68(5), pp. 518-531. (doi: 10.23736/S0026-4725.20.05263-9) (PMID:32319269)
Gaudino, M., Arvind, V., Hameed, I., Di Franco, A., Spadaccio, C., Bhatt, D. L. and Bagiella, E. (2020) Effects of the COVID-19 pandemic on active non-COVID clinical trials. Journal of the American College of Cardiology, 76(13), pp. 1605-1606. (doi: 10.1016/j.jacc.2020.07.051) (PMID:32745501)
Nappi, F., Avtaar Singh, S. S., Spadaccio, C. and Acar, C. (2020) Ross operation 23 years after surgery: it should not be a “forgotten” option. Journal of Cardiac Surgery, 35(4), pp. 952-956. (doi: 10.1111/jocs.14489) (PMID:32115768)
Nappi, F., Spadaccio, C., Acar, C. and El-Hamamsy, I. (2020) Lights and shadows on the Ross procedure: biological solutions for biological problems. Seminars in Thoracic and Cardiovascular Surgery, 32(4), pp. 815-822. (doi: 10.1053/j.semtcvs.2020.04.006) (PMID:32439545)
Nappi, F., Nenna, A., Petitti, T., Spadaccio, C., Gambardella, I., Lusini, M., Chello, M. and Acar, C. (2018) Long-term outcome of cryopreserved allograft for aortic valve replacement. Journal of Thoracic and Cardiovascular Surgery, 156(4), 1357-1365.e6. (doi: 10.1016/j.jtcvs.2018.04.040) (PMID:29759737)
Fraldi, M., Spadaccio, C., Acar, C. and Nappi, F. (2018) Best to clarify to avoid misunderstandings in the biomechanics of Ross Operation: parentheses matter. Annals of Thoracic Surgery, 106(2), pp. 641-642. (doi: 10.1016/j.athoracsur.2018.01.047) (PMID:29477565)
Nappi, F., Nenna, A., Larobina, D., Carotenuto, A. R., Jarraya, M., Spadaccio, C., Fraldi, M., Chello, M., Acar, C. and Carrel, T. (2018) Simulating the ideal geometrical and biomechanical parameters of the pulmonary autograft to prevent failure in the Ross operation. Interactive Cardiovascular and Thoracic Surgery, 27(2), pp. 269-276. (doi: 10.1093/icvts/ivy070) (PMID:29538653)
Spadaccio, C., Dalby, M. and Danton, M. H.D. (2018) Daytime variations in perioperative myocardial injury. Lancet, 391(10135), pp. 2105-2106. (doi: 10.1016/S0140-6736(18)30785-2) (PMID:29856342)
Nappi, F., Spadaccio, C., Mihos, C. G. and Fraldi, M. (2018) Euler's elastica-based biomechanical assessment for neochordal insertion in the treatment of degenerative mitral valve repair. Journal of Thoracic and Cardiovascular Surgery, 155(2), pp. 603-605. (doi: 10.1016/j.jtcvs.2017.09.002) (PMID:29415386)
Avtaar Singh, S. S., Das De, S., Spadaccio, C., Berry, C. and Al-Attar, N. (2017) An overview of different methods of myocardial protection currently employed peri-transplantation. Vessel Plus, 1, pp. 213-229. (doi: 10.20517/2574-1209.2017.26)
Nappi, F., Spadaccio, C. and Sablayrolles, J.-L. (2017) Delayed prosthesis malposition after transcatheter aortic valve implantation causing coronaries obstruction. European Journal of Cardio-Thoracic Surgery, 52(6), pp. 1227-1228. (doi: 10.1093/ejcts/ezx266) (PMID:28950358)
Nappi, F. and Spadaccio, C. (2017) Simplest solutions are not always the cleverest: can we stitch in an infected annulus? Should we rethink the current guidelines? Journal of Thoracic and Cardiovascular Surgery, 154(6), pp. 1899-1900. (doi: 10.1016/j.jtcvs.2017.05.099) (PMID:29132883)
Spadaccio, C., Elkasrawy, K. and Sutherland, F. W.H. (2017) New minimally invasive surgical approach for excision of left atrial myxoma. General Thoracic and Cardiovascular Surgery, 65(10), pp. 605-608. (doi: 10.1007/s11748-017-0779-8) (PMID:28493094)
Nappi, F. and Spadaccio, C. (2017) Biomechanics of failed ischemic mitral valve repair: discovering new frontiers. Journal of Thoracic and Cardiovascular Surgery, 154(3), pp. 832-833. (doi: 10.1016/j.jtcvs.2017.04.035) (PMID:28826151)
Fraldi, M., Spadaccio, C., Mihos, C. G. and Nappi, F. (2017) Analysing the reasons of failure of surgical mitral repair approaches-do we need to better think in biomechanics? Journal of Thoracic Disease, 9(S7), S661-S664. (doi: 10.21037/jtd.2017.06.33) (PMID:28740720) (PMCID:PMC5505944)
Nappi, F., Spadaccio, C., Chello, M. and Mihos, C. G. (2017) Papillary muscle approximation in mitral valve repair for secondary MR. Journal of Thoracic Disease, 9(S7), S635-S639. (doi: 10.21037/jtd.2017.06.98) (PMID:28740718) (PMCID:PMC5505932)
Nappi, F., Spadaccio, C., Mihos, C. G. and Fraldi, M. (2017) Biomechanics raises solution to avoid geometric mitral valve configuration abnormalities in ischemic mitral regurgitation. Journal of Thoracic Disease, 9(S7), S624-S628. (doi: 10.21037/jtd.2017.05.63) (PMID:28740716) (PMCID:PMC5505935)
Nappi, F., Spadaccio, C. and Acar, C. (2017) Use of allogeneic tissue to treat infective valvular disease: Has everything been said? Journal of Thoracic and Cardiovascular Surgery, 153(4), pp. 824-828. (doi: 10.1016/j.jtcvs.2016.09.071) (PMID:27866779)
Spadaccio, C. et al. (2017) Implantation of a poly-L-lactide GCSF-functionalized scaffold in a model of chronic myocardial infarction. Journal of Cardiovascular Translational Research, 10(1), pp. 47-65. (doi: 10.1007/s12265-016-9718-9) (PMID:28116550) (PMCID:PMC5323505)
Spadaccio, C., Nappi, F., Al-Attar, N., Coccia, R., Perluigi, M. and Di Domenico, F. (2017) Introductory editorial: drug-eluting stents or drug-eluting grafts? Insights from proteomic analysis. Drug Target Insights, 10(S1), pp. 15-19. (doi: 10.4137/DTI.S41240) (PMID:28096649) (PMCID:PMC5215111)
Spadaccio, C., Nappi, F., Sablayrolles, J.-L. and Sutherland, F. W.H. (2017) TAVR vs SAVR: rising expectations and changing indications for surgery in response to PARTNER II. Seminars in Thoracic and Cardiovascular Surgery, 29(1), pp. 8-11. (doi: 10.1053/j.semtcvs.2017.01.008) (PMID:28684004)
Nappi, F., Spadaccio, C. and Sablayrolles, J. L. (2016) Pushing the limits in transcatheter aortic valve replacement: high-volume center's effect, overconfidence, or something else? JACC: Cardiovascular Interventions, 9(21), pp. 2186-2188. (doi: 10.1016/j.jcin.2016.08.014) (PMID:27744044)
Nappi, F. and Spadaccio, C. (2016) Coronary artery bypass grafting (CABG) alone in moderate ischemic mitral regurgitation: is CABG really enough? Annals of Translational Medicine, 4(20), 413. (doi: 10.21037/atm.2016.08.47) (PMID:27867965) (PMCID:PMC5107413)
Spadaccio, C., Nappi, F., Al-Attar, N., Sutherland, F. W., Acar, C., Nenna, A., Trombetta, M., Chello, M. and Rainer, A. (2016) Old myths, new concerns: the long-term effects of ascending aorta replacement with Dacron grafts. Not all that glitters is gold. Journal of Cardiovascular Translational Research, 9(4), pp. 334-342. (doi: 10.1007/s12265-016-9699-8) (PMID:27245785)