Dr Giacomo Rossitto
- Honorary Research Fellow (School of Cardiovascular & Metabolic Health)
Publications
2024
Rossi, G. P., Bagordo, D., Rossi, F. B., Pintus, G., Rossitto, G. and Seccia, T. M. (2024) ‘Essential’ arterial hypertension: time for a paradigm change. Journal of Hypertension, 42(8), pp. 1298-1304. (doi: 10.1097/hjh.0000000000003767) (PMID:38748508) (PMCID:PMC11216381)
Rossitto, G., Bertoldi, G., Rutkowski, J. M., Mitchell, B. M. and Delles, C. (2024) Sodium, interstitium, lymphatics, and hypertension - A tale of hydraulics. Hypertension, 81(4), pp. 727-737. (doi: 10.1161/HYPERTENSIONAHA.123.17942) (PMID:38385255)
2023
Bagordo, D., Rossi, G. P., Delles, C. , Wiig, H. and Rossitto, G. (2023) The tangram of sodium and fluid balance: salt series. Hypertension, (doi: 10.1161/HYPERTENSIONAHA.123.19569) (Early Online Publication)
Chen, J. Y., Chew, K. S., Mary, S. , Boder, P., Bagordo, D., Rossi, G. P., Touyz, R. M. , Delles, C. and Rossitto, G. (2023) Skin-specific mechanisms of body fluid regulation in hypertension. Clinical Science, 137(3), pp. 239-250. (doi: 10.1042/CS20220609) (PMID:36648486)
Zhu, R., Shagjaa, T., Rossitto, G., Caroccia, B., Seccia, T. M., Gregori, D. and Rossi, G. P. (2023) Exclusion tests in unilateral primary aldosteronism (ExcluPA) study. Journal of Clinical Endocrinology and Metabolism, 108(2), pp. 496-506. (doi: 10.1210/clinem/dgac654) (PMID:36373399)
2022
Rossitto, G. and Delles, C. (2022) Mechanisms of sodium-mediated injury in cardiovascular disease: old play, new scripts. FEBS Journal, 289(23), pp. 7260-7273. (doi: 10.1111/febs.16155) (PMID:34355504)
Mary, S. , Rossitto, G. and Delles, C. (2022) Pathophysiology of hypertension. In: Nadar, S. and Lip, G. (eds.) Hypertension. Series: Oxford cardiology library. Oxford University Press: Oxford, pp. 11-20. ISBN 9780198870678 (doi: 10.1093/med/9780198870678.003.0002)
Rossi, G. P. and Rossitto, G. (2022) Aldosterone and cardiovascular damage: a new lesson from an old study. Hypertension, 79(9), pp. 1994-1996. (doi: 10.1161/hypertensionaha.122.19662) (PMID:35947644)
Sanga, V., Rossitto, G., Seccia, T. M. and Rossi, G. P. (2022) Management and outcomes of primary aldosteronism in pregnancy: a systematic review. Hypertension, 79(9), pp. 1912-1921. (doi: 10.1161/HYPERTENSIONAHA.121.18858) (PMID:35686552)
Rossitto, G. and Delles, C. (2022) Does excess tissue sodium storage regulate blood pressure? Current Hypertension Reports, 24(5), pp. 115-122. (doi: 10.1007/s11906-022-01180-x) (PMID:35192140) (PMCID:PMC9142429)
Rossi, G. P. et al. (2022) Drug-resistant hypertension in primary aldosteronism patients undergoing adrenal vein sampling: the AVIS-2-RH study. European Journal of Preventive Cardiology, 29(2), e85-e93. (doi: 10.1093/eurjpc/zwaa108) (PMID:33742213)
Delles, C. and Rossitto, G. (2022) Of snails, earthworms, and men: insights into strategies to preserve water. Function, 3(1), zqab071. (doi: 10.1093/function/zqab071) (PMID:35330922) (PMCID:PMC8788808)
2021
Mary, S. , Boder, P., Rossitto, G., Graham, L., Scott, K. , Flynn, A., Kipgen, D., Graham, D. and Delles, C. (2021) Salt loading decreases urinary excretion and increases intracellular accumulation of uromodulin in stroke-prone spontaneously hypertensive rats. Clinical Science, 135(24), pp. 2749-2761. (doi: 10.1042/CS20211017) (PMID:34870708) (PMCID:PMC8689196)
Rossi, G. P. et al. (2021) Feasibility of imaging-guided adrenalectomy in young patients with primary aldosteronism. Hypertension, 79(1), pp. 187-195. (doi: 10.1161/HYPERTENSIONAHA.121.18284) (PMID:34878892)
Murray, E. , Rossitto, G. and Delles, C. (2021) Haemodynamic assessment in hypertension: the soloists and the orchestra. Journal of Hypertension, 39(6), pp. 1109-1111. (doi: 10.1097/HJH.0000000000002796) (PMID:33967215)
Rossitto, G. et al. (2021) High sodium intake, glomerular hyperfiltration and protein catabolism in patients with essential hypertension. Cardiovascular Research, 117(5), pp. 1372-1381. (doi: 10.1093/cvr/cvaa205) (PMID:33053160) (PMCID:PMC8064429)
2020
Rossitto, G. et al. (2020) Reduced lymphatic reserve in heart failure with preserved ejection fraction. Journal of the American College of Cardiology, 76(24), pp. 2817-2829. (doi: 10.1016/j.jacc.2020.10.022) (PMID:33303070) (PMCID:PMC7724570)
Rossitto, G. et al. (2020) Tissue sodium excess is not hypertonic and reflects extracellular volume expansion. Nature Communications, 11, 4222. (doi: 10.1038/s41467-020-17820-2) (PMID:32839436) (PMCID:PMC7445299)
Rossitto, G. et al. (2020) Subtyping of primary aldosteronism in the AVIS-2 study: assessment of selectivity and lateralization. Journal of Clinical Endocrinology and Metabolism, 105(6), pp. 2042-2052. (doi: 10.1210/clinem/dgz017) (PMID:31536622)
2019
Rossi, G. P. et al. (2019) Clinical outcomes of 1625 patients with primary aldosteronism subtyped with adrenal vein sampling. Hypertension, 74(4), pp. 800-808. (doi: 10.1161/HYPERTENSIONAHA.119.13463) (PMID:31476901)
Cameron, A. C., Rossitto, G., Lang, N. N. and Touyz, R. M. (2019) Antihypertensive drugs and vascular health. In: Zimlichman, R., Julius, S. and Mancia, G. (eds.) Prehypertension and Cardiometabolic Syndrome. Series: Updates in hypertension and cardiovascular protection. Springer, pp. 585-605. ISBN 9783319753096 (doi: 10.1007/978-3-319-75310-2_37)
Rossitto, G., Sneddon, M. and Rockson, S. G. (2019) The lymphatic system. In: Touyz, R. M. and Delles, C. (eds.) Textbook of Vascular Medicine. Springer: Cham, pp. 45-57. ISBN 9783030164805 (doi: 10.1007/978-3-030-16481-2_5)
2018
Rossitto, G., Touyz, R. M. , Petrie, M. C. and Delles, C. (2018) Much Ado about N...atrium: modelling tissuesodium as a highly sensitive marker of subclinicaland localized oedema. Clinical Science, 132(24), pp. 2609-2613. (doi: 10.1042/CS20180575) (PMID:30545897) (PMCID:PMC6365627)
Rossitto, G. and Touyz, R. (2018) Dr Giacomo Rossitto interviews Professor Rhian Touyz, on the translational applications of vascular smooth muscle cell biology in cardiovascular disease. [Audio]
Rossitto, G., Battistel, M., Barbiero, G., Bisogni, V., Maiolino, G., Diego, M., Seccia, T. M. and Rossi, G. P. (2018) The subtyping of primary aldosteronism by adrenal vein sampling: sequential blood sampling causes factitious lateralization. Journal of Hypertension, 36(2), pp. 335-343. (doi: 10.1097/HJH.0000000000001564) (PMID:28957852)
Articles
Rossi, G. P., Bagordo, D., Rossi, F. B., Pintus, G., Rossitto, G. and Seccia, T. M. (2024) ‘Essential’ arterial hypertension: time for a paradigm change. Journal of Hypertension, 42(8), pp. 1298-1304. (doi: 10.1097/hjh.0000000000003767) (PMID:38748508) (PMCID:PMC11216381)
Rossitto, G., Bertoldi, G., Rutkowski, J. M., Mitchell, B. M. and Delles, C. (2024) Sodium, interstitium, lymphatics, and hypertension - A tale of hydraulics. Hypertension, 81(4), pp. 727-737. (doi: 10.1161/HYPERTENSIONAHA.123.17942) (PMID:38385255)
Bagordo, D., Rossi, G. P., Delles, C. , Wiig, H. and Rossitto, G. (2023) The tangram of sodium and fluid balance: salt series. Hypertension, (doi: 10.1161/HYPERTENSIONAHA.123.19569) (Early Online Publication)
Chen, J. Y., Chew, K. S., Mary, S. , Boder, P., Bagordo, D., Rossi, G. P., Touyz, R. M. , Delles, C. and Rossitto, G. (2023) Skin-specific mechanisms of body fluid regulation in hypertension. Clinical Science, 137(3), pp. 239-250. (doi: 10.1042/CS20220609) (PMID:36648486)
Zhu, R., Shagjaa, T., Rossitto, G., Caroccia, B., Seccia, T. M., Gregori, D. and Rossi, G. P. (2023) Exclusion tests in unilateral primary aldosteronism (ExcluPA) study. Journal of Clinical Endocrinology and Metabolism, 108(2), pp. 496-506. (doi: 10.1210/clinem/dgac654) (PMID:36373399)
Rossitto, G. and Delles, C. (2022) Mechanisms of sodium-mediated injury in cardiovascular disease: old play, new scripts. FEBS Journal, 289(23), pp. 7260-7273. (doi: 10.1111/febs.16155) (PMID:34355504)
Rossi, G. P. and Rossitto, G. (2022) Aldosterone and cardiovascular damage: a new lesson from an old study. Hypertension, 79(9), pp. 1994-1996. (doi: 10.1161/hypertensionaha.122.19662) (PMID:35947644)
Sanga, V., Rossitto, G., Seccia, T. M. and Rossi, G. P. (2022) Management and outcomes of primary aldosteronism in pregnancy: a systematic review. Hypertension, 79(9), pp. 1912-1921. (doi: 10.1161/HYPERTENSIONAHA.121.18858) (PMID:35686552)
Rossitto, G. and Delles, C. (2022) Does excess tissue sodium storage regulate blood pressure? Current Hypertension Reports, 24(5), pp. 115-122. (doi: 10.1007/s11906-022-01180-x) (PMID:35192140) (PMCID:PMC9142429)
Rossi, G. P. et al. (2022) Drug-resistant hypertension in primary aldosteronism patients undergoing adrenal vein sampling: the AVIS-2-RH study. European Journal of Preventive Cardiology, 29(2), e85-e93. (doi: 10.1093/eurjpc/zwaa108) (PMID:33742213)
Delles, C. and Rossitto, G. (2022) Of snails, earthworms, and men: insights into strategies to preserve water. Function, 3(1), zqab071. (doi: 10.1093/function/zqab071) (PMID:35330922) (PMCID:PMC8788808)
Mary, S. , Boder, P., Rossitto, G., Graham, L., Scott, K. , Flynn, A., Kipgen, D., Graham, D. and Delles, C. (2021) Salt loading decreases urinary excretion and increases intracellular accumulation of uromodulin in stroke-prone spontaneously hypertensive rats. Clinical Science, 135(24), pp. 2749-2761. (doi: 10.1042/CS20211017) (PMID:34870708) (PMCID:PMC8689196)
Rossi, G. P. et al. (2021) Feasibility of imaging-guided adrenalectomy in young patients with primary aldosteronism. Hypertension, 79(1), pp. 187-195. (doi: 10.1161/HYPERTENSIONAHA.121.18284) (PMID:34878892)
Murray, E. , Rossitto, G. and Delles, C. (2021) Haemodynamic assessment in hypertension: the soloists and the orchestra. Journal of Hypertension, 39(6), pp. 1109-1111. (doi: 10.1097/HJH.0000000000002796) (PMID:33967215)
Rossitto, G. et al. (2021) High sodium intake, glomerular hyperfiltration and protein catabolism in patients with essential hypertension. Cardiovascular Research, 117(5), pp. 1372-1381. (doi: 10.1093/cvr/cvaa205) (PMID:33053160) (PMCID:PMC8064429)
Rossitto, G. et al. (2020) Reduced lymphatic reserve in heart failure with preserved ejection fraction. Journal of the American College of Cardiology, 76(24), pp. 2817-2829. (doi: 10.1016/j.jacc.2020.10.022) (PMID:33303070) (PMCID:PMC7724570)
Rossitto, G. et al. (2020) Tissue sodium excess is not hypertonic and reflects extracellular volume expansion. Nature Communications, 11, 4222. (doi: 10.1038/s41467-020-17820-2) (PMID:32839436) (PMCID:PMC7445299)
Rossitto, G. et al. (2020) Subtyping of primary aldosteronism in the AVIS-2 study: assessment of selectivity and lateralization. Journal of Clinical Endocrinology and Metabolism, 105(6), pp. 2042-2052. (doi: 10.1210/clinem/dgz017) (PMID:31536622)
Rossi, G. P. et al. (2019) Clinical outcomes of 1625 patients with primary aldosteronism subtyped with adrenal vein sampling. Hypertension, 74(4), pp. 800-808. (doi: 10.1161/HYPERTENSIONAHA.119.13463) (PMID:31476901)
Rossitto, G., Touyz, R. M. , Petrie, M. C. and Delles, C. (2018) Much Ado about N...atrium: modelling tissuesodium as a highly sensitive marker of subclinicaland localized oedema. Clinical Science, 132(24), pp. 2609-2613. (doi: 10.1042/CS20180575) (PMID:30545897) (PMCID:PMC6365627)
Rossitto, G., Battistel, M., Barbiero, G., Bisogni, V., Maiolino, G., Diego, M., Seccia, T. M. and Rossi, G. P. (2018) The subtyping of primary aldosteronism by adrenal vein sampling: sequential blood sampling causes factitious lateralization. Journal of Hypertension, 36(2), pp. 335-343. (doi: 10.1097/HJH.0000000000001564) (PMID:28957852)
Book Sections
Mary, S. , Rossitto, G. and Delles, C. (2022) Pathophysiology of hypertension. In: Nadar, S. and Lip, G. (eds.) Hypertension. Series: Oxford cardiology library. Oxford University Press: Oxford, pp. 11-20. ISBN 9780198870678 (doi: 10.1093/med/9780198870678.003.0002)
Cameron, A. C., Rossitto, G., Lang, N. N. and Touyz, R. M. (2019) Antihypertensive drugs and vascular health. In: Zimlichman, R., Julius, S. and Mancia, G. (eds.) Prehypertension and Cardiometabolic Syndrome. Series: Updates in hypertension and cardiovascular protection. Springer, pp. 585-605. ISBN 9783319753096 (doi: 10.1007/978-3-319-75310-2_37)
Rossitto, G., Sneddon, M. and Rockson, S. G. (2019) The lymphatic system. In: Touyz, R. M. and Delles, C. (eds.) Textbook of Vascular Medicine. Springer: Cham, pp. 45-57. ISBN 9783030164805 (doi: 10.1007/978-3-030-16481-2_5)
Audio
Rossitto, G. and Touyz, R. (2018) Dr Giacomo Rossitto interviews Professor Rhian Touyz, on the translational applications of vascular smooth muscle cell biology in cardiovascular disease. [Audio]