Dr Li Shen
- Honorary Research Fellow (School of Cardiovascular & Metabolic Health)
Publications
2024
Matsumoto, S. et al. (2024) Beta‐blocker use and outcomes in patients with heart failure and mildly reduced and preserved ejection fraction. European Journal of Heart Failure, (doi: 10.1002/ejhf.3383) (PMID:39215677) (Early Online Publication)
Shen, L. et al. (2024) Revisiting race and the benefit of RAS blockade in heart failure. A meta-analysis of randomized clinical trials. JAMA: Journal of the American Medical Association, 331(24), 2094. (doi: 10.1001/jama.2024.6774) (PMID:38809561)
Matsumoto, S. et al. (2024) Mineralocorticoid receptor antagonists in patients with heart failure and impaired renal function. Journal of the American College of Cardiology, 83(24), pp. 2426-2436. (doi: 10.1016/j.jacc.2024.03.426) (PMID:38739064)
Matsumoto, S. et al. (2024) Effects of sacubitril/valsartan according to polypharmacy status in PARAGON‐HF. European Journal of Heart Failure, 26(5), pp. 1125-1138. (doi: 10.1002/ejhf.3223) (PMID:38587090)
2023
Dobbin, S. J.H. , Shen, L., Petrie, M. C. , Packer, M., Solomon, S. D., McMurray, J. J.V. , Lang, N. N. and Jhund, P. S. (2023) Characteristics and outcomes of patients with a history of cancer recruited to heart failure trials. European Journal of Heart Failure, 25(4), pp. 488-496. (doi: 10.1002/ejhf.2818) (PMID:36919816)
2022
Shen, L. et al. (2022) Accelerated and personalized therapy for heart failure with reduced ejection fraction. European Heart Journal, 43(27), pp. 2573-2587. (doi: 10.1093/eurheartj/ehac210) (PMID:35467706)
Curtain, J. P. et al. (2022) Effect of sacubitril/valsartan on investigator-reported ventricular arrhythmias in PARADIGM-HF. European Journal of Heart Failure, 24(3), pp. 551-561. (doi: 10.1002/ejhf.2419) (PMID:34969175)
2021
Shen, L. et al. (2021) Development and external validation of prognostic models to predict sudden and pump-failure death in patients with HFrEF from PARADIGM-HF and ATMOSPHERE. Clinical Research in Cardiology, 110(8), pp. 1334-1349. (doi: 10.1007/s00392-021-01888-x) (PMID:34101002)
Shen, L. et al. (2021) Developing and validating models to predict sudden death and pump failure death in patients with heart failure and preserved ejection fraction. Clinical Research in Cardiology, 110(8), pp. 1234-1248. (doi: 10.1007/s00392-020-01786-8) (PMID:33301080)
Shen, L. et al. (2021) Incidence and outcomes of pneumonia in patients with heart failure. Journal of the American College of Cardiology, 77(16), pp. 1961-1973. (doi: 10.1016/j.jacc.2021.03.001) (PMID:33888245)
2020
Dewan, P. et al. (2020) The prevalence and importance of frailty in heart failure with reduced ejection fraction – an analysis of PARADIGM-HF and ATMOSPHERE. European Journal of Heart Failure, 22(11), pp. 2123-2133. (doi: 10.1002/ejhf.1832) (PMID:32353205)
Simpson, J. et al. (2020) Prognostic models derived in PARADIGM-HF and validated in ATMOSPHERE and the Swedish Heart Failure Registry to predict mortality and morbidity in chronic heart failure. JAMA Cardiology, 5(4), pp. 432-441. (doi: 10.1001/jamacardio.2019.5850) (PMID:31995119)
Docherty, K. F. et al. (2020) Relationship between heart rate and outcomes in patients in sinus rhythm or atrial fibrillation with heart failure and reduced ejection fraction. European Journal of Heart Failure, 22(3), pp. 528-538. (doi: 10.1002/ejhf.1682) (PMID:31849164)
Shen, L., Jhund, P. and McMurray, J. (2020) Dyslipidaemia, a factor worthy of adjustment: reply. European Journal of Heart Failure, 22(3), pp. 564-565. (doi: 10.1002/ejhf.1718) (PMID:31919977)
2019
Tromp, J. et al. (2019) Age-related characteristics and outcomes of patients with heart failure with preserved ejection fraction. Journal of the American College of Cardiology, 74(5), pp. 601-612. (doi: 10.1016/j.jacc.2019.05.052) (PMID:31370950)
Shen, L. et al. (2019) Insulin treatment and clinical outcomes in patients with diabetes and heart failure with preserved ejection fraction. European Journal of Heart Failure, 21(8), pp. 974-984. (doi: 10.1002/ejhf.1535) (PMID:31271255) (PMCID:PMC7079555)
Balmforth, C. et al. (2019) Outcomes and effect of treatment according to etiology in HFrEF: an analysis of PARADIGM-HF. JACC: Heart Failure, 7(6), pp. 457-465. (doi: 10.1016/j.jchf.2019.02.015) (PMID:31078482)
Dewan, P. et al. (2019) Heart failure with reduced ejection fraction: comparison of patient characteristics and clinical outcomes within Asia and between Asia, Europe and the Americas. European Journal of Heart Failure, 21(5), pp. 577-587. (doi: 10.1002/ejhf.1347) (PMID:30536678) (PMCID:PMC6607486)
Shen, L. et al. (2019) Prior pacemaker implantation and clinical outcomes in patients with heart failure and preserved ejection fraction. JACC: Heart Failure, 7(5), pp. 418-427. (doi: 10.1016/j.jchf.2018.12.006) (PMID:30981744)
Dewan, P. et al. (2019) Income inequality and outcomes in heart failure: a global between-country analysis. JACC: Heart Failure, 7(4), pp. 336-346. (doi: 10.1016/j.jchf.2018.11.005) (PMID:30738981)
Dewan, P. et al. (2019) Differential impact of heart failure with reduced ejection fraction on men and women. Journal of the American College of Cardiology, 73(1), pp. 29-40. (doi: 10.1016/j.jacc.2018.09.081) (PMID:30621948)
2018
Kristensen, S. L., Rørth, R., Jhund, P. S. , Shen, L., Lee, M. M.Y. , Petrie, M. C. , Køber, L. and McMurray, J. J.V. (2018) Microvascular complications in diabetes patients with heart failure and reduced ejection fraction-insights from the Beta-blocker Evaluation of Survival Trial. European Journal of Heart Failure, 20(11), pp. 1549-1556. (doi: 10.1002/ejhf.1201) (PMID:29727039)
Abdul-Rahim, A. H. , Shen, L., Rush, C. J., Jhund, P. S. , Lees, K. R. and McMurray, J. J.V. (2018) Effect of digoxin in patients with heart failure and mid-range (borderline) left ventricular ejection fraction. European Journal of Heart Failure, 20(7), pp. 1139-1145. (doi: 10.1002/ejhf.1160) (PMID:29493058)
Cosmi, F. et al. (2018) Treatment with insulin is associated with worse outcome in patients with chronic heart failure and diabetes. European Journal of Heart Failure, 20(5), pp. 888-895. (doi: 10.1002/ejhf.1146) (PMID:29488676)
Mogensen, U. M. et al. (2018) Effect of sacubitril/valsartan on recurrent events in the prospective comparison of ARNI with ACEI to determine impact on global mortality and morbidity in heart failure trial (PARADIGM-HF). European Journal of Heart Failure, 20(4), pp. 760-768. (doi: 10.1002/ejhf.1139) (PMID:29431251)
2017
Shen, L., Jhund, P. S. and McMurray, J. J.V. (2017) Declining risk of sudden death in heart failure. New England Journal of Medicine, 377(18), pp. 1794-1795. (doi: 10.1056/NEJMc1711901) (PMID:29091558)
Shen, L. et al. (2017) Declining risk of sudden death in heart failure. New England Journal of Medicine, 377(1), pp. 41-51. (doi: 10.1056/NEJMoa1609758) (PMID:28679089)
Articles
Matsumoto, S. et al. (2024) Beta‐blocker use and outcomes in patients with heart failure and mildly reduced and preserved ejection fraction. European Journal of Heart Failure, (doi: 10.1002/ejhf.3383) (PMID:39215677) (Early Online Publication)
Shen, L. et al. (2024) Revisiting race and the benefit of RAS blockade in heart failure. A meta-analysis of randomized clinical trials. JAMA: Journal of the American Medical Association, 331(24), 2094. (doi: 10.1001/jama.2024.6774) (PMID:38809561)
Matsumoto, S. et al. (2024) Mineralocorticoid receptor antagonists in patients with heart failure and impaired renal function. Journal of the American College of Cardiology, 83(24), pp. 2426-2436. (doi: 10.1016/j.jacc.2024.03.426) (PMID:38739064)
Matsumoto, S. et al. (2024) Effects of sacubitril/valsartan according to polypharmacy status in PARAGON‐HF. European Journal of Heart Failure, 26(5), pp. 1125-1138. (doi: 10.1002/ejhf.3223) (PMID:38587090)
Dobbin, S. J.H. , Shen, L., Petrie, M. C. , Packer, M., Solomon, S. D., McMurray, J. J.V. , Lang, N. N. and Jhund, P. S. (2023) Characteristics and outcomes of patients with a history of cancer recruited to heart failure trials. European Journal of Heart Failure, 25(4), pp. 488-496. (doi: 10.1002/ejhf.2818) (PMID:36919816)
Shen, L. et al. (2022) Accelerated and personalized therapy for heart failure with reduced ejection fraction. European Heart Journal, 43(27), pp. 2573-2587. (doi: 10.1093/eurheartj/ehac210) (PMID:35467706)
Curtain, J. P. et al. (2022) Effect of sacubitril/valsartan on investigator-reported ventricular arrhythmias in PARADIGM-HF. European Journal of Heart Failure, 24(3), pp. 551-561. (doi: 10.1002/ejhf.2419) (PMID:34969175)
Shen, L. et al. (2021) Development and external validation of prognostic models to predict sudden and pump-failure death in patients with HFrEF from PARADIGM-HF and ATMOSPHERE. Clinical Research in Cardiology, 110(8), pp. 1334-1349. (doi: 10.1007/s00392-021-01888-x) (PMID:34101002)
Shen, L. et al. (2021) Developing and validating models to predict sudden death and pump failure death in patients with heart failure and preserved ejection fraction. Clinical Research in Cardiology, 110(8), pp. 1234-1248. (doi: 10.1007/s00392-020-01786-8) (PMID:33301080)
Shen, L. et al. (2021) Incidence and outcomes of pneumonia in patients with heart failure. Journal of the American College of Cardiology, 77(16), pp. 1961-1973. (doi: 10.1016/j.jacc.2021.03.001) (PMID:33888245)
Dewan, P. et al. (2020) The prevalence and importance of frailty in heart failure with reduced ejection fraction – an analysis of PARADIGM-HF and ATMOSPHERE. European Journal of Heart Failure, 22(11), pp. 2123-2133. (doi: 10.1002/ejhf.1832) (PMID:32353205)
Simpson, J. et al. (2020) Prognostic models derived in PARADIGM-HF and validated in ATMOSPHERE and the Swedish Heart Failure Registry to predict mortality and morbidity in chronic heart failure. JAMA Cardiology, 5(4), pp. 432-441. (doi: 10.1001/jamacardio.2019.5850) (PMID:31995119)
Docherty, K. F. et al. (2020) Relationship between heart rate and outcomes in patients in sinus rhythm or atrial fibrillation with heart failure and reduced ejection fraction. European Journal of Heart Failure, 22(3), pp. 528-538. (doi: 10.1002/ejhf.1682) (PMID:31849164)
Shen, L., Jhund, P. and McMurray, J. (2020) Dyslipidaemia, a factor worthy of adjustment: reply. European Journal of Heart Failure, 22(3), pp. 564-565. (doi: 10.1002/ejhf.1718) (PMID:31919977)
Tromp, J. et al. (2019) Age-related characteristics and outcomes of patients with heart failure with preserved ejection fraction. Journal of the American College of Cardiology, 74(5), pp. 601-612. (doi: 10.1016/j.jacc.2019.05.052) (PMID:31370950)
Shen, L. et al. (2019) Insulin treatment and clinical outcomes in patients with diabetes and heart failure with preserved ejection fraction. European Journal of Heart Failure, 21(8), pp. 974-984. (doi: 10.1002/ejhf.1535) (PMID:31271255) (PMCID:PMC7079555)
Balmforth, C. et al. (2019) Outcomes and effect of treatment according to etiology in HFrEF: an analysis of PARADIGM-HF. JACC: Heart Failure, 7(6), pp. 457-465. (doi: 10.1016/j.jchf.2019.02.015) (PMID:31078482)
Dewan, P. et al. (2019) Heart failure with reduced ejection fraction: comparison of patient characteristics and clinical outcomes within Asia and between Asia, Europe and the Americas. European Journal of Heart Failure, 21(5), pp. 577-587. (doi: 10.1002/ejhf.1347) (PMID:30536678) (PMCID:PMC6607486)
Shen, L. et al. (2019) Prior pacemaker implantation and clinical outcomes in patients with heart failure and preserved ejection fraction. JACC: Heart Failure, 7(5), pp. 418-427. (doi: 10.1016/j.jchf.2018.12.006) (PMID:30981744)
Dewan, P. et al. (2019) Income inequality and outcomes in heart failure: a global between-country analysis. JACC: Heart Failure, 7(4), pp. 336-346. (doi: 10.1016/j.jchf.2018.11.005) (PMID:30738981)
Dewan, P. et al. (2019) Differential impact of heart failure with reduced ejection fraction on men and women. Journal of the American College of Cardiology, 73(1), pp. 29-40. (doi: 10.1016/j.jacc.2018.09.081) (PMID:30621948)
Kristensen, S. L., Rørth, R., Jhund, P. S. , Shen, L., Lee, M. M.Y. , Petrie, M. C. , Køber, L. and McMurray, J. J.V. (2018) Microvascular complications in diabetes patients with heart failure and reduced ejection fraction-insights from the Beta-blocker Evaluation of Survival Trial. European Journal of Heart Failure, 20(11), pp. 1549-1556. (doi: 10.1002/ejhf.1201) (PMID:29727039)
Abdul-Rahim, A. H. , Shen, L., Rush, C. J., Jhund, P. S. , Lees, K. R. and McMurray, J. J.V. (2018) Effect of digoxin in patients with heart failure and mid-range (borderline) left ventricular ejection fraction. European Journal of Heart Failure, 20(7), pp. 1139-1145. (doi: 10.1002/ejhf.1160) (PMID:29493058)
Cosmi, F. et al. (2018) Treatment with insulin is associated with worse outcome in patients with chronic heart failure and diabetes. European Journal of Heart Failure, 20(5), pp. 888-895. (doi: 10.1002/ejhf.1146) (PMID:29488676)
Mogensen, U. M. et al. (2018) Effect of sacubitril/valsartan on recurrent events in the prospective comparison of ARNI with ACEI to determine impact on global mortality and morbidity in heart failure trial (PARADIGM-HF). European Journal of Heart Failure, 20(4), pp. 760-768. (doi: 10.1002/ejhf.1139) (PMID:29431251)
Shen, L., Jhund, P. S. and McMurray, J. J.V. (2017) Declining risk of sudden death in heart failure. New England Journal of Medicine, 377(18), pp. 1794-1795. (doi: 10.1056/NEJMc1711901) (PMID:29091558)
Shen, L. et al. (2017) Declining risk of sudden death in heart failure. New England Journal of Medicine, 377(1), pp. 41-51. (doi: 10.1056/NEJMoa1609758) (PMID:28679089)