Professor John McGrath
- Honorary Senior Research Fellow (School of Cardiovascular & Metabolic Health)
https://orcid.org/0000-0002-5276-0381Biography
During a long career at the University of Glasgow, I was Head of various departments covering Physiology, Pharmacology and Neuroscience and held the Regius Chair of Physiology 1991-2012.
I was Chairman of The Executive Committee of The Physiological Society 2006-08; had two spells on its Committee or Executive 1988-93 (as local organizer of IUPS 1993) and 2004-2009 (Vice-Chair then Chair of the Executive Committee and founding chair of Publications Committee) and served as Editor-in-Chief of British Journal of Pharmacology 2009-2015.
I am currently an Honorary Professor at the University of Sydney and Emeritus Professor at the University of Glasgow.
Research interests
My research investigates fundamental autonomic mechanisms, receptor pharmacology and their application to therapeutics.
My early investigations of the then-controversial innervation of several smooth muscle preparations proved central to subsequent important discoveries including co-transmission by noradrenaline and ATP (see Nature 294, 759 – 761), signalling by nitric oxide, the discovery of 6 alpha-adrenoceptor subtypes and the life cycle of receptors.
I applied these fundamental findings to therapeutic issues in collaboration with clinicians and the pharmaceutical industry.
Publications
2017
Nguyen, L. P. et al. (2017) β2-Adrenoceptor signaling in airway epithelial cells promotes eosinophilic inflammation, mucous metaplasia, and airway contractility. Proceedings of the National Academy of Sciences of the United States of America, 114(43), E9163-E9171. (doi: 10.1073/pnas.1710196114) (PMID:29073113)
2016
Southan, C. et al. (2016) The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. Nucleic Acids Research, 44(D1), D1054-D1068. (doi: 10.1093/nar/gkv1037) (PMID:26464438) (PMCID:PMC4702778)
2015
Alexander, S. et al. (2015) The Concise Guide to PHARMACOLOGY 2015/16: Overview. British Journal of Pharmacology, 172(24), pp. 5729-5743. (doi: 10.1111/bph.13347) (PMID:26650438)
McGrath, J.C. , Pawson, A.J., Sharman, J.L. and Alexander, S.P.H. (2015) BJP is linking its articles to the IUPHAR/BPS Guide to PHARMACOLOGY. British Journal of Pharmacology, 172(12), pp. 2929-2932. (doi: 10.1111/bph.13112) (PMID:25965085)
McGrath, J. C. (2015) Localization of α-adrenoceptors: JR Vane Medal Lecture. British Journal of Pharmacology, 172(5), pp. 1179-1194. (doi: 10.1111/bph.13008) (PMID:25377869)
2014
Pawson, A.J. et al. (2014) The IUPHAR/BPS guide to PHARMACOLOGY: an expert-driven knowledgebase of drug targets and their ligands. Nucleic Acids Research, 42(D1), D1098-D1106. (doi: 10.1093/nar/gkt1143)
2013
Alexander, S.P.H., Benson, H.E., Faccenda, E., Pawson, A.J., Sharman, J.L., McGrath, J.C. , Catterall, W.A., Spedding, M., Peters, J.A. and Harmar, A.J. (2013) The concise guide to PHARMACOLOGY 2013/14: overview. British Journal of Pharmacology, 170(8), pp. 1449-1458. (doi: 10.1111/bph.12444)
Flacco, N., Parés, J., Serna, E., Segura, V., Vicente, D., Pérez-Aso, M., Noguera, M.A., Ivorra, M.D., McGrath, J.C. and D'Ocon, P. (2013) α1D-Adrenoceptors are responsible for the high sensitivity and the slow time-course of noradrenaline-mediated contraction in conductance arteries. Pharmacology Research and Perspectives, 1(1), e00001. (doi: 10.1002/prp2.1)
McGrath, J. C. (2013) BJP goes online after 66 years on paper. British Journal of Pharmacology, 168(1), (doi: 10.1111/bph.12078) (PMCID:PMC3569995)
Segura, V., Pérez-Aso, M., Montó, F., Carceller, E., Noguera, M.A., Pediani, J. , Milligan, G. , McGrath, I.C. and D’Ocon, P. (2013) Differences in the signaling pathways of α1A- and α1B-adrenoceptors are related to different endosomal targeting. PLoS ONE, 8(5), e64996. (doi: 10.1371/journal.pone.0064996) (PMID:23717684) (PMCID:PMC3663791)
2012
McGrath, J.C. , Spedding, M., Brüün, J. and Harmar, A. (2012) Calling all pharmacologists with time to spare! We need you! Build the drug discovery knowledge base, GuidetoPharmacology.org. British Journal of Pharmacology, 167(7), pp. 1393-1394. (doi: 10.1111/j.1476-5381.2012.02233.x)
Alexander, S.P.H., Benson, H.E., Davenport, A., Mathie, A., McGrath, I.J.C. , Pawson, A.J., Peters, J.A., Sharman, J.L., Spedding, M. and Harmar, A.J. (2012) GuideToPharmacology.org - an update. British Journal of Pharmacology, 167(4), pp. 697-698. (doi: 10.1111/j.1476-5381.2012.02141.x)
Daly, C. J. , Parmryd, I. and McGrath, J. C. (2012) Visualization and analysis of vascular receptors using confocal laser scanning microscopy and fluorescent ligands. Methods in Molecular Biology, 897, pp. 95-107. (doi: 10.1007/978-1-61779-909-9_5)
2011
Stevenson, C., Methven, L., McLachlan, E., Daly, C. and McGrath, J.C. (2011) Investigating the Role of α2-adrenoceptors in Tail Artery of Wild Type Mice and Mice Lacking α1-adrenoceptors (α1-null). Vascular and Smooth Muscle Physiology Themed Meeting, Edinburgh, UK, 06-08 Dec 2011.
McGrath, J.C. (2011) Comment from the Editor-in-Chief on correspondence in this issue on immuno-techniques. British Journal of Pharmacology, 163(6), pp. 1111-1112. (doi: 10.1111/j.1476-5381.2011.01261.x) (PMID:21707586) (PMCID:PMC3144524)
Drummond, G. B., Paterson, D. J., McLoughlin, P. and McGrath, J. C. (2011) Statistics: all together now, one step at a time. Advances in Physiology Education, 35(2), p. 129. (doi: 10.1152/advan.00029.2011) (PMID:21652495)
Daly, C.J. and McGrath, J.C. (2011) Previously unsuspected widespread cellular and tissue distribution of β-adrenoceptors and its relevance to drug action. Trends in Pharmacological Sciences, 32(4), pp. 219-226. (doi: 10.1016/j.tips.2011.02.008)
Alexander, S., Harmar, A. and McGrath, J.C. (2011) New updated GRAC Fifth Edition with searchable online version Launch of new portal Guide to Pharmacology in association with NC-IUPHAR Transporter-Themed Issue. British Journal of Pharmacology, 164(7), pp. 1749-1750. (doi: 10.1111/j.1476-5381.2011.01751.x)
2010
Drummond, G. B., Paterson, D. J. and McGrath, J. C. (2010) ARRIVE: new guidelines for reporting animal research. Experimental Physiology, 95(8), p. 841. (doi: 10.1113/expphysiol.2010.053785) (PMID:20610775)
NC3Rs Reporting Guidelines Working Group, (2010) Animal research: reporting in vivo experiments: the ARRIVE guidelines. Experimental Physiology, 95(8), pp. 842-844. (doi: 10.1113/expphysiol.2010.053793) (PMID:20610776)
Daly, C.J., Ross, R.A., Whyte, J., Henstridge, C.M., Irving, A.J. and McGrath, J.C. (2010) Fluorescent ligand binding reveals heterogeneous distribution of adrenoceptors and ‘cannabinoid-like’ receptors in small arteries. British Journal of Pharmacology, 159(4), pp. 787-796. (doi: 10.1111/j.1476-5381.2009.00608.x)
McGrath, J.C. (2010) 2010 re-launch of BJP [British Journal of Pharmacology]. British Journal of Pharmacology, 159(1), pp. 1-4. (doi: 10.1111/j.1476-5381.2009.00635.x)
Drummond, G.B., Paterson, D.J. and McGrath, J.C. (2010) ARRIVE: new guidelines for reporting animal research. Journal of Physiology, 588(14), p. 2517. (doi: 10.1113/jphysiol.2010.192260)
McGrath, J.C. and Bond, R. A. (2010) Sir James Black (1924-2010). British Journal of Pharmacology, 160, S2. (doi: 10.1111/j.1476-5381.2010.00843.x)
McGrath, J.C. , Drummond, G., McLachlan, E., Kilkenny, C. and Wainwright, C. (2010) Guidelines for reporting experiments involving animals: the ARRIVE guidelines. British Journal of Pharmacology, 160(7), pp. 1573-1576. (doi: 10.1111/j.1476-5381.2010.00873.x)
2009
Methven, L., McBride, M. , Wallace, G.A. and McGrath, J.C. (2009) The α1B/D-adrenoceptor knockout mouse permits isolation of the vascular α1A-adrenoceptor and elucidates its relationship to the other subtypes. British Journal of Pharmacology, 158(1), pp. 209-224. (doi: 10.1111/j.1476-5381.2009.00269.x) (PMID:19572943) (PMCID:PMC2795267)
Milligan, G. and McGrath, J.C. (2009) GPCR theme editorial. British Journal of Pharmacology, 158(1), pp. 1-4. (doi: 10.1111/j.1476-5381.2009.00422.x)
McGrath, J. C. , Hamill, C., Daly, C. J. and Methven, L. (2009) Correlation of the Patency of Myoendothelial Connections with Endothelial Vasodilator Responses in Spontaneously Hypertensive Rats. Journal of Vascular Research, 46(Sup 1), p. 115. (doi: 10.1159/000222318)
McGrath, J.C. (2009) Endothelium in pharmacology: 30 years on. British Journal of Pharmacology, 157(4), pp. 491-493. (doi: 10.1111/j.1476-5381.2009.00366.x)
Methven, L., Simpson, P.C. and McGrath, J.C. (2009) Alpha 1A/B-Knockout mice explain the native Alpha 1D-adrenoceptor's role in vasoconstriction and show that its location is independent of the other Alpha 1-subtypes. British Journal of Pharmacology, 158(7), pp. 1663-1675. (doi: 10.1111/j.1476-5381.2009.00462.x)
Rang, H. and McGrath, J.C. (2009) Continuity and change. British Journal of Pharmacology, 156(1), pp. 1-3. (doi: 10.1111/j.1476-5381.2008.00076.x)
Wainwright, C. and McGrath, J.C. (2009) Editorial. British Journal of Pharmacology, 158(2), pp. 393-394. (doi: 10.1111/j.1476-5381.2009.00457.x)
2008
Hamill, C., Gonzalez, J. M., Methven, L., Daly, C. J. and McGrath, J. C. (2008) Approaches to visualising myoendothelial connections using laser scanning confocal microscopy. Basic and Clinical Pharmacology and Toxicology, 102(s1), p. 15. (doi: 10.1111/j.1742-7843.2008.00262.x)
McGrath, J.C. , Methven, L., Hamill, C., Macmillan, J., Arribas, S., Briones, A., Vila, E. and Daly, C.J. (2008) Which vascular cells have adrenoceptors? Journal of Vascular Research, 45(Supple), 39--. (doi: 10.1159/000113929)
Methven, L., Hamill, C., MacMillan, J., Daly, C.J. , McGrath, J.C. and Simpson, P.C. (2008) Functional responses in the a1AB- adrenoceptor knockout mouse indicate that the a1D- adrenoceptor has a role in the contraction of small mesenteric arteries. Journal of Vascular Research, 45(Supple), 45--. (doi: 10.1159/000113929)
Bexis, S., Cleary, L., McGrath, J.C. , Tanoue, A., Tsujimoto, G. and Docherty, J. R. (2008) α1D-Adrenoceptors mediate nerve and agonist-evoked contractions in mouse vas deferens: evidence obtained from knockout technology. Autonomic and Autacoid Pharmacology, 28(2-3), pp. 81-85. (doi: 10.1111/j.1474-8673.2008.00420.x)
Daly, C.J. , Wallace, G., White, K., Chris, H., Irving, A. and McGrath, J.C. (2008) Visualisation of Vascular Cannabinoid Receptors and their Potential Interaction with α1-adrenergic Receptors. Proceedings of the Physiological Society 13, King's College London, 2008.
Daly, C.J. , Wallace, G., White, K., Henstridge, C., Irving, A. and McGrath, J.C. (2008) Visualisation of Vascular Cannabinoid Receptors and their Potential Interaction with alpha1-adrenergic Receptors. In: Vascular and Smooth Muscle Physiology. Themed Meeting of the Physiological Society, King's College, London, December 2008,
Hamill, C., Gonzalez, J.M., Methven, L., Daly, C.J. and McGrath, J.C. (2008) Approaches to visualising myoendothelial connections using laser scanning confocal microscopy. Journal of Vascular Research, 45(Supple), p. 8. (doi: 10.1159/000113929)
McGrath, J.C. and Cowan, D.A. (2008) Drugs in Sport. British Journal of Pharmacology, 154(3), pp. 493-495. (doi: 10.1038/bjp.2008.171)
Shafaroudi, M.M., Daly, C.J. and McGrath, J.C. (2008) Multiple action sites of alpha2-AR agonist (UK14304) on different adrenoreceptors in mice aorta. Journal of Damghan University of Basic Sciences, 1(3), pp. 111-122.
White, K., McGrath, J.C. and Daly, C.J. (2008) Selective delivery of dsRNA to resistance artery endothelial cells. Journal of Vascular Research, 45(Supple), p. 7. (doi: 10.1159/000113929)
2007
McGrath, J. C. (2007) Simply removing pressure doesn't work, but youthful drug-taking prevents hereditary mid-life failure. Journal of Hypertension, 25(1), pp. 55-56. (doi: 10.1097/HJH.0b013e3280127606) (PMID:17143173)
Morton, J.S., Daly, C.J. , Jackson, V.M. and McGrath, J.C. (2007) α1A-Adrenoceptors mediate contractions to phenylephrine in rabbit penile arteries. British Journal of Pharmacology, 150(1), pp. 112-120.
Arribas, S. M., González, J. M., Briones, A. M., Somoza, B., Daly, C. J. , Vila, E., González, M. C. and McGrath, J. C. (2007) Confocal myography for the study of hypertensive vascular remodelling. Clinical Hemorheology and Microcirculation, 37(1-2), pp. 205-210.
Morton, J., Daly, C., Jackson, V. and McGrath, J. (2007) alpha(1A)-adrenoceptors mediate contractions to phenylephrine in rabbit penile arteries. British Journal of Pharmacology, 150, pp. 112-120. (doi: 10.1038/sj.bjp.0706956)
Morton, J., Jackson, V., Daly, C. and McGrath, J. (2007) Endothelium dependent relaxation in rabbit genital resistance arteries is predominantly mediated by endothelial-derived hyperpolarizing factor in females and nitric oxide in males. Journal of Urology, 177, pp. 786-791. (doi: 10.1016/j.juro.2006.09.072)
Nasuti, C., Cantalamessa, F., Daly, C. and McGrath, J. (2007) Alterations in rabbit aorta induced by types I and II pyrethroids. Environmental Toxicology and Pharmacology, 23, pp. 250-253. (doi: 10.1016/j.etap.2006.08.008)
2006
Gonzalez, J.M., Briones, A.M., Somoza, B., Daly, C.J., Vila, E., Starcher, B., McGrath, J.C. , Gonzalez, M.C. and Arribas, S.M. (2006) Postnatal alterations in elastic fiber organization precede resistance artery narrowing in SHR. American Journal of Physiology: Heart and Circulatory Physiology, 291, H804-H812. (doi: 10.1152/ajpheart.01262.2005)
Ibrahim, J., McGee, A., Graham, D., McGrath, J.C. and Dominiczak, A.F. (2006) Sex-specific differences in cerebral arterial myogenic tone in hypertensive and normotensive rats. American Journal of Physiology: Heart and Circulatory Physiology, 290(3), H1081-H1089. (doi: 10.1152/ajpheart.00752.2005)
McGrath, J. C. and Daly, C. J. (2006) Use of fluorescent ligands and receptors to visualize adrenergic receptors. In: Perez, D. M. (ed.) The Adrenergic Receptors: In the 21st Century. Series: The receptors, III. Humana Press, pp. 151-172. ISBN 9781588294234 (doi: 10.1385/1-59259-931-1:151)
Papay, R., Gaivin, R., Jha, A., McCune, D., McGrath, J. , Rodrigo, M., Simpson, P., Doze, V. and Perez, D. (2006) Localization of the mouse alpha(1A)-adrenergic receptor (AR) in the brain: alpha(1A)AR is expressed in neurons, GABAergic interneurons, and NG2 oligodendrocyte progenitors. Journal of Comparative Neurology, 497, pp. 209-222. (doi: 10.1002/cne.20992)
2005
Briones, A. M., Daly, C. J. , Jimenez-Altayo, F., Martinez-Revelles, S., Gonzalez, J. M., McGrath, J. C. and Vila, E. (2005) Direct demonstration of β1- and evidence against β2- and β3-adrenoceptors, in smooth muscle cells of rat small mesenteric arteries. British Journal of Pharmacology, 146(5), pp. 679-691. (doi: 10.1038/sj.bjp.0706369)
Briones, A. M., Daly, C. J. , Jimenez-Altayo, F., Martinez-Revelles, S., Gonzalez, J. M., McGrath, J. C. and Vila, E. (2005) Direct demonstration of β1- and evidence against β2- and β3-adrenoceptors, in smooth muscle cells of rat small mesenteric arteries. British Journal of Pharmacology, 146(5), pp. 679-691. (doi: 10.1038/sj.bjp.0706369)
Daly, C. J. , McGrath, I. , Townsend, S. and Berkowitz, D. E. (2005) The role of the 1B-adrenergic receptor in vascular structure and function. Hypertension, 45(6), e20-e21. (doi: 10.1161/01.HYP.0000167153.83102.15)
Adler, J., Arribas, S., Briones, A., Daly, C., Deighan, C., McBride, M. , McGrath, J. , Shafaroudi, M. and Vila, E. (2005) New aspects of vascular remodelling: the involvement of all vascular cell types. Experimental Physiology, 90, pp. 469-475. (doi: 10.1113/expphysiol.2005.030130)
Briones, A., Daly, C., Jimenez-Altayo, F., Martinez-Revelles, S., Gonzalez, J., McGrath, J. and Vila, E. (2005) Direct demonstration of beta(1)- and evidence against beta(2)- and beta(3)- adrenoceptors, in smooth muscle cells of rat small mesenteric arteries. British Journal of Pharmacology, 146, pp. 679-691.
Deighan, C., Methven, L., Naghadeh, M., Wokoma, A., Macmillan, J., Daly, C., Tanoue, A., Tsujimoto, G. and McGrath, J. (2005) Insights into the functional roles of alpha(1)-adrenoceptor subtypes in mouse carotid arteries using knockout mice. British Journal of Pharmacology, 144, pp. 558-565. (doi: 10.1038/sj.bjp.0706089)
Miquel, M. R., Segura, V., Ali, Z., D'Ocon, M. P., McGrath, J. C. and Daly, C. J. (2005) 3D image analysis of fluorescent drug binding. Molecular imaging, 40(1), pp. 40-52. (doi: 10.1162/15353500200504172) (PMID:15967125)
Morton, J.S., Daly, C.J. , McGrath, J.C. and Jackson, V.M. (2005) Development of an in vitro method to study vaginal arteries using myography. In: University of Newcastle Winter Meeting, Newcastle, UK, 2005,
Shafaroudi, M., McBride, M. , Deighan, C., Wokoma, A., Macmillan, J., Daly, C. and McGrath, J. (2005) Two "knockout" mouse models demonstrate that aortic vasodilatation is mediated via alpha(2A)-adrenoceptors located on the endothelium. Journal of Pharmacology and Experimental Therapeutics, 314, pp. 804-810. (doi: 10.1124/jpet.105.085944)
Zacharia, J., Hillier, C., Tanoue, A., Tsujimoto, G., Daly, C., McGrath, J. and MacDonald, A. (2005) Evidence for involvement of alpha(1D)-adrenoceptors in contraction of femoral resistance arteries using knockout mice. British Journal of Pharmacology, 146, pp. 942-951. (doi: 10.1038/sj.bjp.0706395)
2004
Ali, Z., McGrath, J.C. and Daly, C.J. (2004) Adrenergic and Serotonergic Synergism in the Mouse Thoracic Aorta. University of Glasgow 2004, 2004.
Deighan, C., Woollhead, A., Colston, J. and McGrath, J. (2004) Hepatocytes from alpha(1B)-adrenoceptor knockout mice reveal compensatory adrenoceptor subtype substitution. British Journal of Pharmacology, 142, pp. 1031-1037. (doi: 10.1038/sj.bjp.0705872)
McBride, M., Daly, C.J. , McGrath, J.C. and Malekzadeh-Shafaroudi, M. (2004) A Study of α2-adrenoceptor-mediated Vasodilatation in Mesenteric Resistance Arteries From Transgenic Mice. University of Glasgow 2004, 2004.
Morton, J.S., Daly, C.J. , Jackson, V.M., Van Der Graff, P.H. and McGrath, J. (2004) Development of an in vitro method to study penile resistance vessels using myography. Proceedings of the British Pharmacological Society, 11(4), 038P.
Papay, R., Gaivin, R., McCune, D., Rorabaugh, B., Macklin, W., McGrath, J. and Perez, D. (2004) Mouse alpha(1B)-adrenergic receptor is expressed in neurons and NG2 oligodendrocytes. Journal of Comparative Neurology, 478, pp. 1-10. (doi: 10.1002/cne.20215)
2003
Briones, A.M., Gonzalez, J.M., Somoza, B., Giraldo, J., Daly, C.J. , Vila, E., Gonzalez, M.C., McGrath, J.C. and Arribas, S.M. (2003) Role of elastin in spontaneously hypertensive rat small mesenteric artery remodelling. Journal of Physiology, 552, pp. 185-195. (doi: 10.1113/jphysiol.2003.046904)
Coats, P., Jarajapu, Y.P.R., Hillier, C., McGrath, J.C. and Daly, C. (2003) The use of fluorescent nuclear dyes and laser scanning confocal microscopy to study the cellular aspects of arterial remodelling in human subjects with critical limb ischaemia. Experimental Physiology, 88(4), pp. 547-554. (doi: 10.1113/eph8802552) (PMID:12861343)
McGrath, J.C. and Daly, C.J. (2003) Do fluorescent drugs show you more than you wanted to know? British Journal of Pharmacology, 139(2), pp. 187-189. (doi: 10.1038/sj.bjp.0705288)
Ali, Z., McGrath, J.C. , Tsujimoto, G. and Daly, C.J. (2003) Inhibition of 5-hydroxytryptamine-mediated Contraction by α1-adrenoceptor Antagonist in Mouse Thoracic Aorta. XXXII Congress of the Spanish Society of Physiological Sciences International Joint Meeting with The Physiological Society, Puerto de la Cruz, Tenerife, 13-17 Feb 2003.
Briones, A., González, J. M., Somoza, B., Giraldo, J., Daly, C. , McGrath, I. , Vila, E., González, C. and Arribas, S. M. (2003) Relationship Between Elastin Organisation and Structural and Mechanical Abnormalities in Resistance Arteries From Spontaneously Hypertensive Rats. XXXII Congress of the Spanish Society of Physiological Sciences International Joint Meeting with The Physiological Society, Puerto de la Cruz, Tenerife, 13-17 Feb 2003.
McBride, M., Daly, C.J. , Tsujimoto, G. and McGrath, J.C. (2003) Removal of the α1B-adrenoceptor Uncovers an α1D Component in Mesenteric Resistance Arteries. XXXII Congress of the Spanish Society of Physiological Sciences International Joint Meeting with The Physiological Society, Puerto de la Cruz, Tenerife, 13-17 Feb 2003.
Coats, P., Jarajapu, Y., Hillier, C., McGrath, J. and Daly, C. (2003) The use of fluorescent nuclear dyes and laser scanning confocal microscopy to study the cellular aspects of arterial remodelling in human subjects with critical limb ischaemia. Experimental Physiology, 88, pp. 547-554.
Daly, C. and McGrath, J. (2003) Fluorescent ligands, antibodies, and proteins for the study of receptors. Pharmacology and Therapeutics, 100, pp. 101-118. (doi: 10.1016/j.pharmthera.2003.08.001)
Jarajapu, Y. P. R., McGrath, J. C. , Hillier, C. and MacDonald, A. (2003) The α1-adrenoceptor profile in human skeletal muscle resistance arteries in critical limb ischaemia. Cardiovascular Research, 57, pp. 554-562. (doi: 10.1016/S0008-6363(02)00669-7) (PMID:12566128)
Jimenez-Altayo, F., Giraldo, J., McGrath, J. and Vila, E. (2003) Enhanced noradrenergic transmission in the spontaneously hypertensive rat anococcygeus muscle. British Journal of Pharmacology, 140, pp. 773-779. (doi: 10.1038/sj.bjp.0705480)
2002
Ali, Z., McGrath, J.C. and Daly, C.J. (2002) Characterisation of the contractile alpha1- adrenoceptor response in the mouse thoracic aorta. British Journal of Pharmacology, 137(Suppl.), 92P.
McGrath, J.C. (2002) Bretylium or 6-OHDA-resistant, action potential-evoked Ca 2+ transients in varicosities of the mouse vas deferens: commentary on Jackson and Cunnane. British Journal of Pharmacology, 135(8), pp. 1841-1843. (doi: 10.1038/sj.bjp.0704676) (PMID:11959785) (PMCID:PMC1573332)
Ali, Z., Daly, C., Deighan, C., McBride, M. , McGee, A., McGrath, J. and Mennie, D. (2002) A knockout approach indicates a minor vasoconstrictor role for vascular alpha(1B)-adrenoceptors in mouse. Physiological Genomics, 9, pp. 85-91. (doi: 10.1152/physiolgenomics.00065.2001)
Brahmadevara, N., Macdonald, A., McGrath, J. and Daly, C. (2002) Measurement of cellular and tissue distribution of beta-adrenoceptors in rat thoracic aorta using BODIPY-CGP 12177. British Journal of Pharmacology, 137(Suppl.), 93P.
Daly, C. et al. (2002) Analysing the 3D structure of blood vessels using confocal microscopy. Microscopy and Analysis, 92, pp. 5-8.
Daly, C. , Pediani, J. , Mackenzie, J.F. and McGrath, J. (2002) Visualising agonist and antagonist interactions: the value of fluorescent ligands. Pharmacologist, 44(2), A73.
Jarajapu, Y.P.R., Macdonald, A., Hillier, C., McGrath, J. , Mackenzie, J.F. and Daly, C. (2002) Quantitative imaging of QAPB-associated fluorescence in smooth muscle cells from human skeletal muscle resistance arteries. British Journal of Pharmacology, 135(Suppl.), 303P.
McBride, M., Daly, C. and McGrath, J. (2002) Alpha1 and alpha2-adrenoceptors mediating resistance artery contraction as revealed by receptor “knockouts”. Pharmacologist, 44(2), A79.
McBride, M., Daly, C. and McGrath, J. (2002) Contractile responses to UK 14304 in the mouse tail artery differ when the drug is administered cumulatively or non-cumulatively. In: 7th Annual Meeting of the European Council for Blood Pressure and Cardiovascular Research (ECCR), Seeheim, Germany, 11-13 Oct 2002,
McBride, M., Daly, C. and McGrath, J. (2002) Contractile responses to UK14304 are inhibited by low concentrations of rauwolscine but are unaffected by prazosin in mouse tail artery. British Journal of Pharmacology, 137(Suppl.), 91P.
McBride, M., Daly, C. and McGrath, J. (2002) Tail arteries from D79N mice show reduced responses to UK14304 compared with wild type. British Journal of Pharmacology, 135(Suppl.), 304P.
McGrath, J. and Daly, C. (2002) Fluorescence technologies for the study of receptors. Pharmacologist, 44(2), A73.
Shafaroudi, M., Daly, C. and McGrath, J. (2002) Analysis of alpha2-adrenoceptor- and angiotensin-mediated responses in mouse aorta. Pharmacologist, 44(2), A79.
2001
Jarajapu, Y. P.R., Johnston, F., Berry, C. , Renwick, A., McGrath, J. C. , MacDonald, A. and Hillier, C. (2001) Functional characterization of alpha(1)-adrenoceptor subtypes in human subcutaneous resistance arteries. Journal of Pharmacology and Experimental Therapeutics, 299(2), pp. 729-734. (PMID:11602687)
Jarajapu, Y. P.R., Coats, P., McGrath, J. C. , Hillier, C. and MacDonald, A. (2001) Functional characterization of alpha(1)-adrenoceptor subtypes in human skeletal muscle resistance arteries. British Journal of Pharmacology, 133(5), pp. 679-686. (doi: 10.1038/sj.bjp.0704130) (PMID:11429392) (PMCID:PMC1572837)
Boumaza, S., Arribas, S. M., Osborne-Pellegrin, M., McGrath, J. C. , Laurent, S., Lacolley, P. and Challande, P. (2001) Fenestrations of the carotid internal elastic lamina and structural adaptation in stroke-prone spontaneously hypertensive rats. Hypertension, 37(4), pp. 1101-1107. (doi: 10.1161/01.HYP.37.4.1101) (PMID:11304510)
Jarajapu, Y. P.R., Coats, P., McGrath, J. C. , MacDonald, A. and Hillier, C. (2001) Increased alpha(1)- and alpha(2)-adrenoceptor-mediated contractile responses of human skeletal muscle resistance arteries in chronic limb ischemia. Cardiovascular Research, 49(1), pp. 218-225. (doi: 10.1016/S0008-6363(00)00224-8) (PMID:11121814)
Chalmers, G., Clayton, R., Dagg, K., McGrath, J. , Thomson, L. and Thomson, N. (2001) The effect of acute alteration in oxygen tension on the bronchodilator response to salbutamol in vitro and in vivo in man. Pulmonary Pharmacology and Therapeutics, 14, pp. 99-105.
Zuscik, M.J. et al. (2001) Hypotension, autonomic failure, and cardiac hypertrophy in transgenic mice overexpressing the alpha(1B)-adrenergic receptor. Journal of Biological Chemistry, 276(17), pp. 13738-13743. (doi: 10.1074/jbc.M008693200)
2000
Shang, C., McGrath, J. , Daly, C. and Barker, J. (2000) Modelling and classification of vascular smooth muscle cell images. Electronics Letters, 36(18), pp. 1532-1533. (doi: 10.1049/el:20001106)
Mackenzie, J. F., Daly, C. J. , Pediani, J. D. and McGrath, J. C. (2000) Quantitative imaging in live human cells reveals intracellular alpha(1)-adrenoceptor ligand-binding sites. Journal of Pharmacology and Experimental Therapeutics, 294(2), pp. 434-443.
Pediani, J. D. , Mackenzie, J. F., Heeley, R. P., Daly, C. J. and McGrath, J. C. (2000) Single-cell recombinant pharmacology: bovine α1a-adrenoceptors in rat-1 fibroblasts release intracellular Ca2+, display subtype-characteristic agonism and antagonism, and exhibit an antagonist-reversible inverse concentration-response phase. Journal of Pharmacology and Experimental Therapeutics, 293(3), pp. 887-895.
Daly, C.J. , Vila, E., Arribas, S.M., Pagakis, S., Thebault, B., Maddison, J., Pederson, J. and McGrath, J.C. (2000) 3-dimensional analysis of vascular structure, function & receptor distribution using confocal laser scanning microscopy. In: 10th Porto Meeting on Adrenergic Mechanisms, Porto, Portugal, 25-27 Sep 2000,
Granitsioti, P., Daly, C. , Kirk, D. and McGrath, J. (2000) Physiology of the human vas deferens; Clinical importance. In: 10th Porto Meeting on Adrenergic Mechanisms, Porto, Portugal, 25-27 Sept 2000,
Mackenzie, J.F., Pediani, J. , Daly, C. , Deighan, C. and McGrath, J. (2000) Fluorescent ligand binding to alpha1-adrenoceptors in murine hepatocytes. In: 10th Porto Meeting on Adrenergic Mechanisms, Porto, Portugal, 25-27 Sept 2000, P2.
Shang, C., Daly, C. , McGrath, J. and Barker, J. (2000) Neural network based classification of cell images via estimation of fractal dimensions. In: International Conference on Artificial Neural Networks in Medicine and Biology, Goteburg, Sweden, 13-16 May 2000, pp. 111-116. (doi: 10.1007/978-1-4471-0513-8_15)
1999
Shaw, A. M., Bunton, D. C., Fisher, A., McGrath, J. C. , Montgomery, I., Daly, C. and MacDonald, A. (1999) V-shaped cushion at the origin of bovine pulmonary supernumerary arteries: structure and putative function. Journal of Applied Physiology, 87(6), pp. 2348-2356.
McGrath, J.C. , Mackenzie, J.F. and Daly, C. J. (1999) Pharmacological implications of cellular localization of α1-adrenoceptors in native smooth muscle cells. Journal of Autonomic Pharmacology, 19(6), pp. 303-310. (doi: 10.1111/j.1365-2680.1999.tb00002.x)
Mackenzie, J.F., Daly, C.J. , Luo, D. and McGrath, J.C. (1999) Cellular localisation of alpha1 -adrenoceptors in human primary smooth muscle cells derived from the prostate of patients with benign prostatic hypertrophy. European Urology, 36(S1), p. 115. (doi: 10.1159/000052331)
McGrath, J.C. , Nagadeh, M.A., Pediani, J.D. , Mackenzie, J.F. and Daly, C.J. (1999) Importance of agonists in α-adrenoceptor classification and localisation of α1-adrenoceptors in human prostate. European Urology, 36(S1), pp. 80-88. (doi: 10.1159/000052326)
McGrath, J.C. , Mackenzie, J.F. and Daly, C.J. (1999) Sub-cellular localisation of alpha1-adrenoceptors in live cells and tissues. In: British Pharmacological Societ Joint Spring Meeting with Portuguese Pharmacological Society, Porto, Portugal, 8-9 Apr 1999, 133P.
1998
Luo, D., Barker, J., McGrath, J.C. and Daly, C.J. (1998) Iterative multilevel thresholding and splitting for 3D segmentation of live cell nuclei using laser scanning confocal microscopy. Journal of Computer-Assisted Microscopy, 10(4), pp. 151-162. (doi: 10.1023/A:1023482003483)
Daly, C.J. , Milligan, C.M., Milligan, G. , Mackenzie, J.F. and McGrath, J.C. (1998) Cellular localization and pharmacological characterization of functioning alpha-1 adrenoceptors by fluorescent ligand binding and image analysis reveals identical binding properties of clustered and diffuse populations of receptors. Journal of Pharmacology and Experimental Therapeutics, 286(2), pp. 984-990.
Daly, C.J. , Cotecchia, S. and McGrath, J.C. (1998) Low frequency electrical field stimulation elicits responses in segments of mouse tail artery which are slower in alpha1B-knockout mice than in control mice. Naunyn-Schmiedeberg's Archives of Pharmacology, 358(S2), P6.40.
Giummelly, P., Colas, T., Atkinson, J., Robert, A., Daly, C.J. , Luo, D. and McGrath, J.C. (1998) Fluorescence of the medial aortic elastic lamella in elastocalcinotic rats. Naunyn-Schmiedeberg's Archives of Pharmacology, 358(S1), P37.36.
Luo, D., Daly, C.J. , Mackenzie, J.F., McGrory, S.P., Robert, A. and McGrath, J.C. (1998) 3D remodelling of alpha1-adrenoceptors in live cells using a fluorescent ligand, QAPB and confocal laser scanning microscopy. Naunyn-Schmiedeberg's Archives of Pharmacology, 358(S2), P6.44.
Mackenzie, J.F., Daly, C.D. and McGrath, J.C. (1998) Comparison and validation of human a1-adrenoceptor binding characteristics on live, whole cells using radioligand binding and confocal laser scanning microscopic techniques. Naunyn-Schmiedeberg's Archives of Pharmacology, 358(S2), P6.45.
Pediani, J.D. , Mackenzie, J.F., Daly, C.J. and McGrath, J.C. (1998) Functional pharmacological properties of the cloned bovine a 1a-adrenoceptor (a 1a-AR) stably expressed in rat-1 fibroblasts. Naunyn-Schmiedeberg's Archives of Pharmacology, 358(Supp.2), p. 646.
Pediani, J. , Mackenzie, J.F., Daly, C. and McGrath, J. (1998) Comparison of functional and binding pharmacological properties of the cloned bovine a 1a-adrenoceptor (a 1a-AR) stably expressed in rat-1 fibroblasts. Naunyn-Schmiedeberg's Archives of Pharmacology, 358(S2), P6.47.
Robert, A., Daly, C.J. , Luo, D., Montgomery, I. and McGrath, J.C. (1998) Decrease of the medial carotid elastin componentin rabbit ligated coronary heart failure model. Naunyn-Schmiedeberg's Archives of Pharmacology, 358(S2), P57.22.
Robert, A., Daly, C.J. and McGrath, J.C. (1998) Decrease of in vitro carotid compliance in rabbit heart failure model. In: Heart Failure Update, Glasgow, UK, 1998, p. 8.
1997
Daly, C.J., , de la Rue, S.A., Luo, D. and McGrath, J.C. (1997) 3D-distribution of a-adrenoceptors in blood vessel lack of staining on endothelial cells. Journal of Vascular Research, 34(Sup 1), p. 34. (doi: 10.1159/000317489)
1996
McGrath, J. C. , Arribas, S. and Daly, C. J. (1996) Fluorescent ligands for the study of receptors. Trends in Pharmacological Sciences, 17(11), pp. 393-399. (doi: 10.1016/S0165-6147(96)40004-9)
Arribas, S. M., Gordon, J. F., Daly, C. J. , Dominiczak, A. F. and McGrath, J. C. (1996) Confocal microscopic characterization of a lesion in a cerebral vessel of the stroke-prone spontaneously hypertensive rat. Stroke, 27(6), pp. 1118-1123. (doi: 10.1161/01.STR.27.6.1118)
McGrath, J. and Daly, C. (1996) Functional antagonism and receptor-induced fluorescence in rat anococcygeus. FASEB Journal, 10(3), p. 2448.
1995
McGrath, J.C. , Arribas, S., Daly, C.J. and Gordon, J.F. (1995) Confocal microscopy for structure and realtime pharmacology in blood vessels. Journal of Human Hypertension, 9(8), pp. 645-647.
McGrath, J.C. et al. (1995) The relationship between the adrenoceptor and nonadrenoceptor-mediated effects of imidazoline- and imidazole-containing compounds. Annals of the New York Academy of Sciences, 763(1), pp. 591-605. (doi: 10.1111/j.1749-6632.1995.tb32454.x)
Arribas, S., Daly, C. , Dominiczak, A. and McGrath, J. (1995) Reduced vasodilator responses to noradrenaline correlates with decreased density of -adrenoceptor flurophore binding in the basilar artery from old WKY rats. Methods and Finding in Experimental and Clinical Pharmacology, 17, CO30.
Arribas, S.M., Gordon, J.F., Daly, C.J. , Davidson, A., Dominiczak, A. and McGrath, J.C. (1995) Structural and functional alterations in the basilar artery from stroke prone spontaneously hypertensive rats. In: 7th European Meeting on Hypertension, Milan, Italy, 9-12 Jun 1995, p. 12.
McGrath, J. and Daly, C. (1995) Viewing adrenoceptors; past, present, and future; commentary and a new technique. Pharmacology Communications, 1(6), pp. 269-279.
1994
Arribas, S., Gordon, J.F., Daly, C. , Davidson, A., Dominiczak, A. and McGrath, J.C. (1994) Vascular smooth muscle rearrangement and impaired contractions in basilar artery of the stroke-prone spontaneously hypertensive rat. Journal of Hypertension, 12(11), p. 1319.
Arriba, S.M., Daly, C.J. , Gordon, J.F. and McGrath, J.C. (1994) Confocal myography: applications for the study of resistance arteries. In: Halpern, W., Bevan, J.A., Brayden, J., Dustan, H. and Nelson, M. (eds.) The Resistance Arteries: Integration of the Regulatory Pathways. Series: Experimental biology and medicine (26). Humana Press: New York, NY, pp. 259-264. ISBN 9781617370083
Daly, C.J. , Gordon, J.F. and McGrath, J.C. (1994) The use of confocal microscopy for the study of resistance artery structure and function. Journal of Vascular Research, 31(Sup 1), p. 10. (doi: 10.1159/000159068)
Macmillan, J.M., Daly, C.J. and McGrath, J.C. (1994) The innervation and alpha-adrenoceptor profile of rabbit isolated dorsal cutaneous and sub-cutaneous resistance arteries. Journal of Vascular Research, 31(Sup 1), p. 30. (doi: 10.1159/000317452)
1993
Daly, C.J. , Gordon, J.F. and McGrath, J.C. (1993) Dimensional analysis of smooth muscle cell reactivity within the rat resistance artery using confocal microscopy. In: XXXII Congress of the International Union of Physiological Sciences, Glasgow, UK, 1-6 Aug 1993,
Daly, C.J. , Gordon, J.F. and McGrath, J.C. (1993) Observation of vasodilatation in small arteries with confocal microscopy. In: XXXII Congress of the International Union of Physiological Sciences, Glasgow, UK, 1-6 Aug 1993,
Gordon, J.F., Daly, C.J. and McGrath, J.C. (1993) Analysis of rat resistance artery structure in pressurised vessels using confocal microscopy. In: XXXII Congress of the International Union of Physiological Sciences, Glasgow, UK, 1-6 Aug 1993,
1992
Gordon, J.F., Baird, M., Daly, C.J. and McGrath, J.C. (1992) Endogenous nitric oxide modulates sympathetic neuroeffector transmission in the isolated rabbit lateral saphenous vein. Journal of Cardiovascular Pharmacology, 20(Sup 12), S68-S71.
MacDonald, A., Daly, C.J. , Bulloch, J.M. and McGrath, J.C. (1992) Contributions of α1-adrenoceptors, α2-adrenoceptors and P2x-purinoceptors to neurotransmission in several rabbit isolated blood vessels: role of neuronal uptake and autofeedback. British Journal of Pharmacology, 105(2), pp. 347-354. (doi: 10.1111/j.1476-5381.1992.tb14257.x)
Daly, C.J. , Gordon, J.F. and McGrath, J.C. (1992) Endogenous nitric oxide modulates sympathetic neuroeffector transmission in the rabbit isolated lateral saphenous vein. Journal of Vascular Research, 29(2), p. 99. (doi: 10.1159/000317442)
Daly, C.J. , Gordon, J.F. and McGrath, J.C. (1992) The use of fluorescent nuclear dyes for the study of blood vessel structure and function: novel applications of existing techniques. Journal of Vascular Research, 29(1), pp. 41-48. (doi: 10.1159/000158930)
Daly, C.J. , MacLean, M.R. and McGrath, J.C. (1992) Electrical field stimulation of rabbit isolated cutaneous and pulmonary microvessels demonstrates the diversity of innervation within the microcirculation. British Journal of Pharmacology, 107(S2), 453P. (doi: 10.1111/j.1476-5381.1992.tb16283.x)
1991
Bulloch, J.M., MacDonald, A., Daly, C.J. and McGrath, J.C. (1991) Effect of cocaine on neurotransmission in rabbit isolated blood vessels. Fundamental and Clinical Pharmacology, 5(5), p. 454. (doi: 10.1111/j.1472-8206.1991.tb00732.x)
Dunn, W.R., Daly, C.J. , McGrath, J.C. and Wilson, V.G. (1991) A comparison of the effects of angiotensin II and Bay K 8644 on responses to noradrenaline mediated via postjunctional α1-and α2-adrenoceptors in rabbit isolated blood vessels. British Journal of Pharmacology, 103(2), pp. 1475-1483. (doi: 10.1111/j.1476-5381.1991.tb09814.x)
Dunn, W.R., Daly, C.J. , McGrath, J.C. and Wilson, V.G. (1991) The effects of nifedipine on alpha 2-adrenoceptor-mediated contractions in several isolated blood vessels from the rabbit. British Journal of Pharmacology, 103(2), pp. 1493-1499. (doi: 10.1111/j.1476-5381.1991.tb09816.x)
Daly, C. , Gordon, J.F. and McGrath, J. (1991) A fluorescence image analysis method for the study of smooth muscle cell interaction within the vascular wall of small blood vessels. Journal of Vascular Research, 28(4), p. 281. (doi: 10.1159/000158878)
Daly, C.J. , Gordon, J.F. and McGrath, J.C. (1991) Assessment of cell viability within the wall of rat mesenteric arteries. Journal of Vascular Research, 28(4), p. 282. (doi: 10.1159/000158878)
Daly, C.J. , Gordon, J.F. and McGrath, J.C. (1991) Fluorescence image analysis methods for the study of smooth muscle cell interaction within the vascular wall of small blood vessels. In: Mulvany, M. J. (ed.) Resistance Arteries, Structure and Function. Excerpta Medica: Amsterdam, pp. 339-343. ISBN 9780444891938
Daly, C.J. , Gordon, J.F., McGrath, J.C. and Spedding, M. (1991) Quantification of experimentally induced ischaemic damage to smooth muscle cell membranes within the wall of resistance arteries. Blood Vessels, 28(4), p. 281. (doi: 10.1159/000158878)
1990
Bulloch, J.M., Daly, C.J. , Dunn, W.R., MacDonald, A. and McGrath, J.C. (1990) α,β-methylene ATP can potentiate as well as inhibit nerve mediated responses of rabbit blood vessels and guinea pig vas deferens. European Journal of Pharmacology, 183(2), pp. 543-544. (doi: 10.1016/0014-2999(90)93450-5)
Daly, C.J. , McGrath, J.C. and Wilson, V.G. (1990) Activation of venous alpha2-adrenoceptors by UK-14304 in the presence of low extracellular Ca2+ is associated with an initial transient contraction. British Journal of Pharmacology, 100(S1), 465P. (doi: 10.1111/j.1476-5381.1990.tb16988.x)
MacDonald, A., Daly, C.J. , Wilson, V.G. and McGrath, J.C. (1990) Effects of prejunctional a-adrenoceptor activation on neurotransmission in the rabbit saphenous artery. British Journal of Pharmacology, 99(S1), 53P. (doi: 10.1111/j.1476-5381.1990.tb16587.x)
Daly, C.J. , Dunn, W.R., McGrath, J.C. , Miller, D.J. and Wilson, V.G. (1990) An examination of the sources of calcium for contractions mediated by postjunctional α1- and α2-adrenoceptors in several blood vessels isolated from the rabbit. British Journal of Pharmacology, 99(2), pp. 253-260. (doi: 10.1111/j.1476-5381.1990.tb14690.x)
Daly, C.J. , McGrath, J.C. and Wilson, V.G. (1990) Angiotensin II selectively potentiates "innervated" post-junctional alpha2-adrenoceptors in the rabbit isolated plantaris vein. Journal of Autonomic Pharmacology, 10(1), 17P. (doi: 10.1111/j.1474-8673.1990.tb00002.x)
Daly, C.J. , McGrath, J.C. and Wilson, V.G. (1990) Ca++ coupling mechanisms and veinous alpha2-adrenoceptors - the effect of angiotensin II. Journal of Autonomic Pharmacology, 10(1), 16P. (doi: 10.1111/j.1474-8673.1990.tb00002.x)
Daly, C.J. , Gordon, J., Boyle, F.C., Gillespie, J.S., McGrath, J.C. , Moss, V.A. and Spurway, N.C. (1990) Fluorescent myography: the analysis of isolated vascular smooth muscle cells of the rat labelled with bisbenzamide during vasoconstriction. Journal of Physiology, 429(Suppl.), 11P.
Gordon, J.F., Daly, C.J. , Boyle, F.C., Kusel, J.R., Gillespie, J.S. and McGrath, J.C. (1990) A simple fluorescence-based cell viability assay for use in rat blood vessels in vitro. Journal of Physiology, 429(s), 10P.
Melville, C.A. , Trainor, M., McGrath, J.C. , Daly, C. , O'Dowd, J.J. and Miller, D.J. (1990) Carnosine shows alpha-adrenoceptor agonist and antagonist properties in saphenous vein isolated from rabbit. Journal of Physiology, 427(Suppl.), 29P.
McGrath, J.C. , Bulloch, J., Daly, C.J. and MacDonald, A. (1990) Contributions of different receptors to vasoconstrictor co-transmission in rabbit isolated arteries and veins. Journal of Vascular Research, 27(1), pp. 28-63. (doi: 10.1159/000158794)
1989
Daly, C.J. , Dunn, W.R., McGrath, J. and Wilson, V.G. (1989) A Comparison of the actions of BAY K-8644 and angiotensin II on extracellular calcium-dependent contractile responses mediated by postjunctional alpha2-adrenoceptors. Annals of the New York Academy of Sciences, 560, pp. 440-443. (doi: 10.1111/j.1749-6632.1989.tb24131.x)
Daly, C.J. , McGrath, J.C. and Wilson, V.G. (1989) Preliminary evidence for the release of cellular-bound calcium by post-junctional alpha2-adrenoceptors in the rabbit isolated ear vein. Journal of Physiology, 414(Suppl.), 57P.
McGrath, J.C. , Daly, C.J. , Dunn, W.R., MacDonald, A., Macmillan, J.B., Templeton, A.G.B. and Wilson, V.G. (1989) Variation in participation of postjunctional alpha1 and alpha2-adrenoceptors and P2y purinoceptors in vascular sympathetic co-transmission: modulation by drugs and hormones. In: XXXIst International Congress of Physiological Sciences, Helsinki, Finland, 9-14 Jul 1989, p. 4376.
McGrath, J.C. , Daly, C.J. , Dunn, W.R., MacLennan, S.J., Macmillan, J.B., Templeton, A.G.B. and Wilson, V.G. (1989) Physiological modulation of alpha-adreno- and 5HT- receptor expression in blood vessels. Journal of Vascular Medicine and Biology, 1, p. 187.
Wilson, V.G., McGrath, J.C. and Daly, C.J. (1989) Does basal release of an endothelium-derived relaxing factor modulate alpha-adrenoceptor function in the rabbit saphenous vein? Journal of Vascular Medicine and Biology, 1, p. 211.
1988
Bulloch, J.M., Daly, C.J. , MacDonald, A., McGrath, J.C. and Wilson, V.G. (1988) The effect of nifedipine on nerve-mediated responses of blood vessels in vitro and in vivo. British Journal of Pharmacology, 95(S1), 563P. (doi: 10.1111/j.1476-5381.1988.tb16614.x)
Daly, C.J. , Dunn, W.R., McGrath, J.C. and Wilson, V.G. (1988) An attempt at selective protection from phenoxybenzamine of postjunctional α-adrenoceptor subtypes mediating contractions to noradrenaline in the rabbit isolated saphenous vein. British Journal of Pharmacology, 95(2), pp. 501-511. (doi: 10.1111/j.1476-5381.1988.tb11670.x)
Daly, C.J. , Dunn, W.R., McGrath, J.C. and Wilson, V.G. (1988) Effect of angiotensin II on responses to noradrenaline mediated via post-junctional alpha-1 and alpha2-adrenoceptors in isolated rabbit blood vessels. British Journal of Pharmacology, 95(S1), 475P-589P. (doi: 10.1111/j.1476-5381.1988.tb16614.x)
Daly, C.J. , McGrath, J.C. and Wilson, V.G. (1988) An examination of the postjunctional α-adrenoceptor subtypes for (−)-noradrenaline in several isolated blood vessels from the rabbit. British Journal of Pharmacology, 95(2), pp. 473-484. (doi: 10.1111/j.1476-5381.1988.tb11668.x)
Daly, C.J. , McGrath, J.C. and Wilson, V.G. (1988) Pharmacological analysis of postjunctional α-adrenoceptors mediating contractions to (−)-noradrenaline in the rabbit isolated lateral saphenous vein can be explained by interacting responses to simultaneous activation of α1-and α2-adrenoceptors. British Journal of Pharmacology, 95(2), pp. 485-500. (doi: 10.1111/j.1476-5381.1988.tb11669.x)
Daly, C.J. , McGrath, J.C. and Wilson, V.G. (1988) Evidence that the population of postjunctional-adrenoceptors mediating contraction of smooth muscle in the rabbit isolated ear vein is predominantly α2. British Journal of Pharmacology, 94(4), pp. 1085-1090. (doi: 10.1111/j.1476-5381.1988.tb11626.x)
1987
Daly, C.J. , McGrath, J.C. and Wilson, V.G. (1987) α-Adrenoceptor-mediated contractions in the rabbit saphenous vein : the influence of endothelial cells. British Journal of Pharmacology, 92(S1), 776P. (doi: 10.1111/j.1476-5381.1987.tb16603.x)
Daly, C.J. , McGrath, J.C. and Wilson, V.G. (1987) Isolation of post-junctional alpha2-adrenoceptors in the rabbit isolated saphenous vein with phenoxybenzamine. British Journal of Pharmacology, 92(S1), 775P. (doi: 10.1111/j.1476-5381.1987.tb16603.x)
Dainty, I.A., Daly, C.J. , McGrath, J.C. , Sinclair, J. and Spedding, M. (1987) Measurement and analysis of analogue signals from a Linseis chart recorder using a BBC microcomputer. British Journal of Pharmacology, 91(Suppl.), p. 506.
Daly, C.J. , McGrath, J.C. and Wilson, V.G. (1987) Post-junctional alpha-adrenoceptors subtype(s) for(-)-noradrenaline in the rabbit isolated saphenous vein. British Journal of Pharmacology, 91(Suppl.), p. 397.
Dainty, I.A., Daly, C.J. , McGrath, J.C. , Sinclair, J. and Spedding, M. (1987) A simple, inexpensive method of collection, storage and analysis of data for the BBC microcomputer. In: Glasgow Meeting of the Physiological Society, Glasgow, UK, 19-20 Jun 1987, p. 22.
1985
Daly, C.J. , McGrath, J.C. , Muir, A.G.H. and O'Brien, J.W. (1985) Ca++-dependence of noradrenaline-induced contraction in rat aortic smooth muscle. British Journal of Pharmacology, 86(S2), 659P-815P. (doi: 10.1111/j.1476-5381.1985.tb14737.x)
Articles
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Southan, C. et al. (2016) The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. Nucleic Acids Research, 44(D1), D1054-D1068. (doi: 10.1093/nar/gkv1037) (PMID:26464438) (PMCID:PMC4702778)
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McGrath, J. C. (2015) Localization of α-adrenoceptors: JR Vane Medal Lecture. British Journal of Pharmacology, 172(5), pp. 1179-1194. (doi: 10.1111/bph.13008) (PMID:25377869)
Pawson, A.J. et al. (2014) The IUPHAR/BPS guide to PHARMACOLOGY: an expert-driven knowledgebase of drug targets and their ligands. Nucleic Acids Research, 42(D1), D1098-D1106. (doi: 10.1093/nar/gkt1143)
Alexander, S.P.H., Benson, H.E., Faccenda, E., Pawson, A.J., Sharman, J.L., McGrath, J.C. , Catterall, W.A., Spedding, M., Peters, J.A. and Harmar, A.J. (2013) The concise guide to PHARMACOLOGY 2013/14: overview. British Journal of Pharmacology, 170(8), pp. 1449-1458. (doi: 10.1111/bph.12444)
Flacco, N., Parés, J., Serna, E., Segura, V., Vicente, D., Pérez-Aso, M., Noguera, M.A., Ivorra, M.D., McGrath, J.C. and D'Ocon, P. (2013) α1D-Adrenoceptors are responsible for the high sensitivity and the slow time-course of noradrenaline-mediated contraction in conductance arteries. Pharmacology Research and Perspectives, 1(1), e00001. (doi: 10.1002/prp2.1)
McGrath, J. C. (2013) BJP goes online after 66 years on paper. British Journal of Pharmacology, 168(1), (doi: 10.1111/bph.12078) (PMCID:PMC3569995)
Segura, V., Pérez-Aso, M., Montó, F., Carceller, E., Noguera, M.A., Pediani, J. , Milligan, G. , McGrath, I.C. and D’Ocon, P. (2013) Differences in the signaling pathways of α1A- and α1B-adrenoceptors are related to different endosomal targeting. PLoS ONE, 8(5), e64996. (doi: 10.1371/journal.pone.0064996) (PMID:23717684) (PMCID:PMC3663791)
McGrath, J.C. , Spedding, M., Brüün, J. and Harmar, A. (2012) Calling all pharmacologists with time to spare! We need you! Build the drug discovery knowledge base, GuidetoPharmacology.org. British Journal of Pharmacology, 167(7), pp. 1393-1394. (doi: 10.1111/j.1476-5381.2012.02233.x)
Alexander, S.P.H., Benson, H.E., Davenport, A., Mathie, A., McGrath, I.J.C. , Pawson, A.J., Peters, J.A., Sharman, J.L., Spedding, M. and Harmar, A.J. (2012) GuideToPharmacology.org - an update. British Journal of Pharmacology, 167(4), pp. 697-698. (doi: 10.1111/j.1476-5381.2012.02141.x)
Daly, C. J. , Parmryd, I. and McGrath, J. C. (2012) Visualization and analysis of vascular receptors using confocal laser scanning microscopy and fluorescent ligands. Methods in Molecular Biology, 897, pp. 95-107. (doi: 10.1007/978-1-61779-909-9_5)
McGrath, J.C. (2011) Comment from the Editor-in-Chief on correspondence in this issue on immuno-techniques. British Journal of Pharmacology, 163(6), pp. 1111-1112. (doi: 10.1111/j.1476-5381.2011.01261.x) (PMID:21707586) (PMCID:PMC3144524)
Drummond, G. B., Paterson, D. J., McLoughlin, P. and McGrath, J. C. (2011) Statistics: all together now, one step at a time. Advances in Physiology Education, 35(2), p. 129. (doi: 10.1152/advan.00029.2011) (PMID:21652495)
Daly, C.J. and McGrath, J.C. (2011) Previously unsuspected widespread cellular and tissue distribution of β-adrenoceptors and its relevance to drug action. Trends in Pharmacological Sciences, 32(4), pp. 219-226. (doi: 10.1016/j.tips.2011.02.008)
Alexander, S., Harmar, A. and McGrath, J.C. (2011) New updated GRAC Fifth Edition with searchable online version Launch of new portal Guide to Pharmacology in association with NC-IUPHAR Transporter-Themed Issue. British Journal of Pharmacology, 164(7), pp. 1749-1750. (doi: 10.1111/j.1476-5381.2011.01751.x)
Drummond, G. B., Paterson, D. J. and McGrath, J. C. (2010) ARRIVE: new guidelines for reporting animal research. Experimental Physiology, 95(8), p. 841. (doi: 10.1113/expphysiol.2010.053785) (PMID:20610775)
NC3Rs Reporting Guidelines Working Group, (2010) Animal research: reporting in vivo experiments: the ARRIVE guidelines. Experimental Physiology, 95(8), pp. 842-844. (doi: 10.1113/expphysiol.2010.053793) (PMID:20610776)
Daly, C.J., Ross, R.A., Whyte, J., Henstridge, C.M., Irving, A.J. and McGrath, J.C. (2010) Fluorescent ligand binding reveals heterogeneous distribution of adrenoceptors and ‘cannabinoid-like’ receptors in small arteries. British Journal of Pharmacology, 159(4), pp. 787-796. (doi: 10.1111/j.1476-5381.2009.00608.x)
McGrath, J.C. (2010) 2010 re-launch of BJP [British Journal of Pharmacology]. British Journal of Pharmacology, 159(1), pp. 1-4. (doi: 10.1111/j.1476-5381.2009.00635.x)
Drummond, G.B., Paterson, D.J. and McGrath, J.C. (2010) ARRIVE: new guidelines for reporting animal research. Journal of Physiology, 588(14), p. 2517. (doi: 10.1113/jphysiol.2010.192260)
McGrath, J.C. and Bond, R. A. (2010) Sir James Black (1924-2010). British Journal of Pharmacology, 160, S2. (doi: 10.1111/j.1476-5381.2010.00843.x)
McGrath, J.C. , Drummond, G., McLachlan, E., Kilkenny, C. and Wainwright, C. (2010) Guidelines for reporting experiments involving animals: the ARRIVE guidelines. British Journal of Pharmacology, 160(7), pp. 1573-1576. (doi: 10.1111/j.1476-5381.2010.00873.x)
Methven, L., McBride, M. , Wallace, G.A. and McGrath, J.C. (2009) The α1B/D-adrenoceptor knockout mouse permits isolation of the vascular α1A-adrenoceptor and elucidates its relationship to the other subtypes. British Journal of Pharmacology, 158(1), pp. 209-224. (doi: 10.1111/j.1476-5381.2009.00269.x) (PMID:19572943) (PMCID:PMC2795267)
Milligan, G. and McGrath, J.C. (2009) GPCR theme editorial. British Journal of Pharmacology, 158(1), pp. 1-4. (doi: 10.1111/j.1476-5381.2009.00422.x)
McGrath, J. C. , Hamill, C., Daly, C. J. and Methven, L. (2009) Correlation of the Patency of Myoendothelial Connections with Endothelial Vasodilator Responses in Spontaneously Hypertensive Rats. Journal of Vascular Research, 46(Sup 1), p. 115. (doi: 10.1159/000222318)
McGrath, J.C. (2009) Endothelium in pharmacology: 30 years on. British Journal of Pharmacology, 157(4), pp. 491-493. (doi: 10.1111/j.1476-5381.2009.00366.x)
Methven, L., Simpson, P.C. and McGrath, J.C. (2009) Alpha 1A/B-Knockout mice explain the native Alpha 1D-adrenoceptor's role in vasoconstriction and show that its location is independent of the other Alpha 1-subtypes. British Journal of Pharmacology, 158(7), pp. 1663-1675. (doi: 10.1111/j.1476-5381.2009.00462.x)
Rang, H. and McGrath, J.C. (2009) Continuity and change. British Journal of Pharmacology, 156(1), pp. 1-3. (doi: 10.1111/j.1476-5381.2008.00076.x)
Wainwright, C. and McGrath, J.C. (2009) Editorial. British Journal of Pharmacology, 158(2), pp. 393-394. (doi: 10.1111/j.1476-5381.2009.00457.x)
Hamill, C., Gonzalez, J. M., Methven, L., Daly, C. J. and McGrath, J. C. (2008) Approaches to visualising myoendothelial connections using laser scanning confocal microscopy. Basic and Clinical Pharmacology and Toxicology, 102(s1), p. 15. (doi: 10.1111/j.1742-7843.2008.00262.x)
McGrath, J.C. , Methven, L., Hamill, C., Macmillan, J., Arribas, S., Briones, A., Vila, E. and Daly, C.J. (2008) Which vascular cells have adrenoceptors? Journal of Vascular Research, 45(Supple), 39--. (doi: 10.1159/000113929)
Methven, L., Hamill, C., MacMillan, J., Daly, C.J. , McGrath, J.C. and Simpson, P.C. (2008) Functional responses in the a1AB- adrenoceptor knockout mouse indicate that the a1D- adrenoceptor has a role in the contraction of small mesenteric arteries. Journal of Vascular Research, 45(Supple), 45--. (doi: 10.1159/000113929)
Bexis, S., Cleary, L., McGrath, J.C. , Tanoue, A., Tsujimoto, G. and Docherty, J. R. (2008) α1D-Adrenoceptors mediate nerve and agonist-evoked contractions in mouse vas deferens: evidence obtained from knockout technology. Autonomic and Autacoid Pharmacology, 28(2-3), pp. 81-85. (doi: 10.1111/j.1474-8673.2008.00420.x)
Hamill, C., Gonzalez, J.M., Methven, L., Daly, C.J. and McGrath, J.C. (2008) Approaches to visualising myoendothelial connections using laser scanning confocal microscopy. Journal of Vascular Research, 45(Supple), p. 8. (doi: 10.1159/000113929)
McGrath, J.C. and Cowan, D.A. (2008) Drugs in Sport. British Journal of Pharmacology, 154(3), pp. 493-495. (doi: 10.1038/bjp.2008.171)
Shafaroudi, M.M., Daly, C.J. and McGrath, J.C. (2008) Multiple action sites of alpha2-AR agonist (UK14304) on different adrenoreceptors in mice aorta. Journal of Damghan University of Basic Sciences, 1(3), pp. 111-122.
White, K., McGrath, J.C. and Daly, C.J. (2008) Selective delivery of dsRNA to resistance artery endothelial cells. Journal of Vascular Research, 45(Supple), p. 7. (doi: 10.1159/000113929)
McGrath, J. C. (2007) Simply removing pressure doesn't work, but youthful drug-taking prevents hereditary mid-life failure. Journal of Hypertension, 25(1), pp. 55-56. (doi: 10.1097/HJH.0b013e3280127606) (PMID:17143173)
Morton, J.S., Daly, C.J. , Jackson, V.M. and McGrath, J.C. (2007) α1A-Adrenoceptors mediate contractions to phenylephrine in rabbit penile arteries. British Journal of Pharmacology, 150(1), pp. 112-120.
Arribas, S. M., González, J. M., Briones, A. M., Somoza, B., Daly, C. J. , Vila, E., González, M. C. and McGrath, J. C. (2007) Confocal myography for the study of hypertensive vascular remodelling. Clinical Hemorheology and Microcirculation, 37(1-2), pp. 205-210.
Morton, J., Daly, C., Jackson, V. and McGrath, J. (2007) alpha(1A)-adrenoceptors mediate contractions to phenylephrine in rabbit penile arteries. British Journal of Pharmacology, 150, pp. 112-120. (doi: 10.1038/sj.bjp.0706956)
Morton, J., Jackson, V., Daly, C. and McGrath, J. (2007) Endothelium dependent relaxation in rabbit genital resistance arteries is predominantly mediated by endothelial-derived hyperpolarizing factor in females and nitric oxide in males. Journal of Urology, 177, pp. 786-791. (doi: 10.1016/j.juro.2006.09.072)
Nasuti, C., Cantalamessa, F., Daly, C. and McGrath, J. (2007) Alterations in rabbit aorta induced by types I and II pyrethroids. Environmental Toxicology and Pharmacology, 23, pp. 250-253. (doi: 10.1016/j.etap.2006.08.008)
Gonzalez, J.M., Briones, A.M., Somoza, B., Daly, C.J., Vila, E., Starcher, B., McGrath, J.C. , Gonzalez, M.C. and Arribas, S.M. (2006) Postnatal alterations in elastic fiber organization precede resistance artery narrowing in SHR. American Journal of Physiology: Heart and Circulatory Physiology, 291, H804-H812. (doi: 10.1152/ajpheart.01262.2005)
Ibrahim, J., McGee, A., Graham, D., McGrath, J.C. and Dominiczak, A.F. (2006) Sex-specific differences in cerebral arterial myogenic tone in hypertensive and normotensive rats. American Journal of Physiology: Heart and Circulatory Physiology, 290(3), H1081-H1089. (doi: 10.1152/ajpheart.00752.2005)
Papay, R., Gaivin, R., Jha, A., McCune, D., McGrath, J. , Rodrigo, M., Simpson, P., Doze, V. and Perez, D. (2006) Localization of the mouse alpha(1A)-adrenergic receptor (AR) in the brain: alpha(1A)AR is expressed in neurons, GABAergic interneurons, and NG2 oligodendrocyte progenitors. Journal of Comparative Neurology, 497, pp. 209-222. (doi: 10.1002/cne.20992)
Briones, A. M., Daly, C. J. , Jimenez-Altayo, F., Martinez-Revelles, S., Gonzalez, J. M., McGrath, J. C. and Vila, E. (2005) Direct demonstration of β1- and evidence against β2- and β3-adrenoceptors, in smooth muscle cells of rat small mesenteric arteries. British Journal of Pharmacology, 146(5), pp. 679-691. (doi: 10.1038/sj.bjp.0706369)
Briones, A. M., Daly, C. J. , Jimenez-Altayo, F., Martinez-Revelles, S., Gonzalez, J. M., McGrath, J. C. and Vila, E. (2005) Direct demonstration of β1- and evidence against β2- and β3-adrenoceptors, in smooth muscle cells of rat small mesenteric arteries. British Journal of Pharmacology, 146(5), pp. 679-691. (doi: 10.1038/sj.bjp.0706369)
Daly, C. J. , McGrath, I. , Townsend, S. and Berkowitz, D. E. (2005) The role of the 1B-adrenergic receptor in vascular structure and function. Hypertension, 45(6), e20-e21. (doi: 10.1161/01.HYP.0000167153.83102.15)
Adler, J., Arribas, S., Briones, A., Daly, C., Deighan, C., McBride, M. , McGrath, J. , Shafaroudi, M. and Vila, E. (2005) New aspects of vascular remodelling: the involvement of all vascular cell types. Experimental Physiology, 90, pp. 469-475. (doi: 10.1113/expphysiol.2005.030130)
Briones, A., Daly, C., Jimenez-Altayo, F., Martinez-Revelles, S., Gonzalez, J., McGrath, J. and Vila, E. (2005) Direct demonstration of beta(1)- and evidence against beta(2)- and beta(3)- adrenoceptors, in smooth muscle cells of rat small mesenteric arteries. British Journal of Pharmacology, 146, pp. 679-691.
Deighan, C., Methven, L., Naghadeh, M., Wokoma, A., Macmillan, J., Daly, C., Tanoue, A., Tsujimoto, G. and McGrath, J. (2005) Insights into the functional roles of alpha(1)-adrenoceptor subtypes in mouse carotid arteries using knockout mice. British Journal of Pharmacology, 144, pp. 558-565. (doi: 10.1038/sj.bjp.0706089)
Miquel, M. R., Segura, V., Ali, Z., D'Ocon, M. P., McGrath, J. C. and Daly, C. J. (2005) 3D image analysis of fluorescent drug binding. Molecular imaging, 40(1), pp. 40-52. (doi: 10.1162/15353500200504172) (PMID:15967125)
Shafaroudi, M., McBride, M. , Deighan, C., Wokoma, A., Macmillan, J., Daly, C. and McGrath, J. (2005) Two "knockout" mouse models demonstrate that aortic vasodilatation is mediated via alpha(2A)-adrenoceptors located on the endothelium. Journal of Pharmacology and Experimental Therapeutics, 314, pp. 804-810. (doi: 10.1124/jpet.105.085944)
Zacharia, J., Hillier, C., Tanoue, A., Tsujimoto, G., Daly, C., McGrath, J. and MacDonald, A. (2005) Evidence for involvement of alpha(1D)-adrenoceptors in contraction of femoral resistance arteries using knockout mice. British Journal of Pharmacology, 146, pp. 942-951. (doi: 10.1038/sj.bjp.0706395)
Deighan, C., Woollhead, A., Colston, J. and McGrath, J. (2004) Hepatocytes from alpha(1B)-adrenoceptor knockout mice reveal compensatory adrenoceptor subtype substitution. British Journal of Pharmacology, 142, pp. 1031-1037. (doi: 10.1038/sj.bjp.0705872)
Morton, J.S., Daly, C.J. , Jackson, V.M., Van Der Graff, P.H. and McGrath, J. (2004) Development of an in vitro method to study penile resistance vessels using myography. Proceedings of the British Pharmacological Society, 11(4), 038P.
Papay, R., Gaivin, R., McCune, D., Rorabaugh, B., Macklin, W., McGrath, J. and Perez, D. (2004) Mouse alpha(1B)-adrenergic receptor is expressed in neurons and NG2 oligodendrocytes. Journal of Comparative Neurology, 478, pp. 1-10. (doi: 10.1002/cne.20215)
Briones, A.M., Gonzalez, J.M., Somoza, B., Giraldo, J., Daly, C.J. , Vila, E., Gonzalez, M.C., McGrath, J.C. and Arribas, S.M. (2003) Role of elastin in spontaneously hypertensive rat small mesenteric artery remodelling. Journal of Physiology, 552, pp. 185-195. (doi: 10.1113/jphysiol.2003.046904)
Coats, P., Jarajapu, Y.P.R., Hillier, C., McGrath, J.C. and Daly, C. (2003) The use of fluorescent nuclear dyes and laser scanning confocal microscopy to study the cellular aspects of arterial remodelling in human subjects with critical limb ischaemia. Experimental Physiology, 88(4), pp. 547-554. (doi: 10.1113/eph8802552) (PMID:12861343)
McGrath, J.C. and Daly, C.J. (2003) Do fluorescent drugs show you more than you wanted to know? British Journal of Pharmacology, 139(2), pp. 187-189. (doi: 10.1038/sj.bjp.0705288)
Coats, P., Jarajapu, Y., Hillier, C., McGrath, J. and Daly, C. (2003) The use of fluorescent nuclear dyes and laser scanning confocal microscopy to study the cellular aspects of arterial remodelling in human subjects with critical limb ischaemia. Experimental Physiology, 88, pp. 547-554.
Daly, C. and McGrath, J. (2003) Fluorescent ligands, antibodies, and proteins for the study of receptors. Pharmacology and Therapeutics, 100, pp. 101-118. (doi: 10.1016/j.pharmthera.2003.08.001)
Jarajapu, Y. P. R., McGrath, J. C. , Hillier, C. and MacDonald, A. (2003) The α1-adrenoceptor profile in human skeletal muscle resistance arteries in critical limb ischaemia. Cardiovascular Research, 57, pp. 554-562. (doi: 10.1016/S0008-6363(02)00669-7) (PMID:12566128)
Jimenez-Altayo, F., Giraldo, J., McGrath, J. and Vila, E. (2003) Enhanced noradrenergic transmission in the spontaneously hypertensive rat anococcygeus muscle. British Journal of Pharmacology, 140, pp. 773-779. (doi: 10.1038/sj.bjp.0705480)
Ali, Z., McGrath, J.C. and Daly, C.J. (2002) Characterisation of the contractile alpha1- adrenoceptor response in the mouse thoracic aorta. British Journal of Pharmacology, 137(Suppl.), 92P.
McGrath, J.C. (2002) Bretylium or 6-OHDA-resistant, action potential-evoked Ca 2+ transients in varicosities of the mouse vas deferens: commentary on Jackson and Cunnane. British Journal of Pharmacology, 135(8), pp. 1841-1843. (doi: 10.1038/sj.bjp.0704676) (PMID:11959785) (PMCID:PMC1573332)
Ali, Z., Daly, C., Deighan, C., McBride, M. , McGee, A., McGrath, J. and Mennie, D. (2002) A knockout approach indicates a minor vasoconstrictor role for vascular alpha(1B)-adrenoceptors in mouse. Physiological Genomics, 9, pp. 85-91. (doi: 10.1152/physiolgenomics.00065.2001)
Brahmadevara, N., Macdonald, A., McGrath, J. and Daly, C. (2002) Measurement of cellular and tissue distribution of beta-adrenoceptors in rat thoracic aorta using BODIPY-CGP 12177. British Journal of Pharmacology, 137(Suppl.), 93P.
Daly, C. et al. (2002) Analysing the 3D structure of blood vessels using confocal microscopy. Microscopy and Analysis, 92, pp. 5-8.
Daly, C. , Pediani, J. , Mackenzie, J.F. and McGrath, J. (2002) Visualising agonist and antagonist interactions: the value of fluorescent ligands. Pharmacologist, 44(2), A73.
Jarajapu, Y.P.R., Macdonald, A., Hillier, C., McGrath, J. , Mackenzie, J.F. and Daly, C. (2002) Quantitative imaging of QAPB-associated fluorescence in smooth muscle cells from human skeletal muscle resistance arteries. British Journal of Pharmacology, 135(Suppl.), 303P.
McBride, M., Daly, C. and McGrath, J. (2002) Alpha1 and alpha2-adrenoceptors mediating resistance artery contraction as revealed by receptor “knockouts”. Pharmacologist, 44(2), A79.
McBride, M., Daly, C. and McGrath, J. (2002) Contractile responses to UK14304 are inhibited by low concentrations of rauwolscine but are unaffected by prazosin in mouse tail artery. British Journal of Pharmacology, 137(Suppl.), 91P.
McBride, M., Daly, C. and McGrath, J. (2002) Tail arteries from D79N mice show reduced responses to UK14304 compared with wild type. British Journal of Pharmacology, 135(Suppl.), 304P.
McGrath, J. and Daly, C. (2002) Fluorescence technologies for the study of receptors. Pharmacologist, 44(2), A73.
Shafaroudi, M., Daly, C. and McGrath, J. (2002) Analysis of alpha2-adrenoceptor- and angiotensin-mediated responses in mouse aorta. Pharmacologist, 44(2), A79.
Jarajapu, Y. P.R., Johnston, F., Berry, C. , Renwick, A., McGrath, J. C. , MacDonald, A. and Hillier, C. (2001) Functional characterization of alpha(1)-adrenoceptor subtypes in human subcutaneous resistance arteries. Journal of Pharmacology and Experimental Therapeutics, 299(2), pp. 729-734. (PMID:11602687)
Jarajapu, Y. P.R., Coats, P., McGrath, J. C. , Hillier, C. and MacDonald, A. (2001) Functional characterization of alpha(1)-adrenoceptor subtypes in human skeletal muscle resistance arteries. British Journal of Pharmacology, 133(5), pp. 679-686. (doi: 10.1038/sj.bjp.0704130) (PMID:11429392) (PMCID:PMC1572837)
Boumaza, S., Arribas, S. M., Osborne-Pellegrin, M., McGrath, J. C. , Laurent, S., Lacolley, P. and Challande, P. (2001) Fenestrations of the carotid internal elastic lamina and structural adaptation in stroke-prone spontaneously hypertensive rats. Hypertension, 37(4), pp. 1101-1107. (doi: 10.1161/01.HYP.37.4.1101) (PMID:11304510)
Jarajapu, Y. P.R., Coats, P., McGrath, J. C. , MacDonald, A. and Hillier, C. (2001) Increased alpha(1)- and alpha(2)-adrenoceptor-mediated contractile responses of human skeletal muscle resistance arteries in chronic limb ischemia. Cardiovascular Research, 49(1), pp. 218-225. (doi: 10.1016/S0008-6363(00)00224-8) (PMID:11121814)
Chalmers, G., Clayton, R., Dagg, K., McGrath, J. , Thomson, L. and Thomson, N. (2001) The effect of acute alteration in oxygen tension on the bronchodilator response to salbutamol in vitro and in vivo in man. Pulmonary Pharmacology and Therapeutics, 14, pp. 99-105.
Zuscik, M.J. et al. (2001) Hypotension, autonomic failure, and cardiac hypertrophy in transgenic mice overexpressing the alpha(1B)-adrenergic receptor. Journal of Biological Chemistry, 276(17), pp. 13738-13743. (doi: 10.1074/jbc.M008693200)
Shang, C., McGrath, J. , Daly, C. and Barker, J. (2000) Modelling and classification of vascular smooth muscle cell images. Electronics Letters, 36(18), pp. 1532-1533. (doi: 10.1049/el:20001106)
Mackenzie, J. F., Daly, C. J. , Pediani, J. D. and McGrath, J. C. (2000) Quantitative imaging in live human cells reveals intracellular alpha(1)-adrenoceptor ligand-binding sites. Journal of Pharmacology and Experimental Therapeutics, 294(2), pp. 434-443.
Pediani, J. D. , Mackenzie, J. F., Heeley, R. P., Daly, C. J. and McGrath, J. C. (2000) Single-cell recombinant pharmacology: bovine α1a-adrenoceptors in rat-1 fibroblasts release intracellular Ca2+, display subtype-characteristic agonism and antagonism, and exhibit an antagonist-reversible inverse concentration-response phase. Journal of Pharmacology and Experimental Therapeutics, 293(3), pp. 887-895.
Shaw, A. M., Bunton, D. C., Fisher, A., McGrath, J. C. , Montgomery, I., Daly, C. and MacDonald, A. (1999) V-shaped cushion at the origin of bovine pulmonary supernumerary arteries: structure and putative function. Journal of Applied Physiology, 87(6), pp. 2348-2356.
McGrath, J.C. , Mackenzie, J.F. and Daly, C. J. (1999) Pharmacological implications of cellular localization of α1-adrenoceptors in native smooth muscle cells. Journal of Autonomic Pharmacology, 19(6), pp. 303-310. (doi: 10.1111/j.1365-2680.1999.tb00002.x)
Mackenzie, J.F., Daly, C.J. , Luo, D. and McGrath, J.C. (1999) Cellular localisation of alpha1 -adrenoceptors in human primary smooth muscle cells derived from the prostate of patients with benign prostatic hypertrophy. European Urology, 36(S1), p. 115. (doi: 10.1159/000052331)
McGrath, J.C. , Nagadeh, M.A., Pediani, J.D. , Mackenzie, J.F. and Daly, C.J. (1999) Importance of agonists in α-adrenoceptor classification and localisation of α1-adrenoceptors in human prostate. European Urology, 36(S1), pp. 80-88. (doi: 10.1159/000052326)
Luo, D., Barker, J., McGrath, J.C. and Daly, C.J. (1998) Iterative multilevel thresholding and splitting for 3D segmentation of live cell nuclei using laser scanning confocal microscopy. Journal of Computer-Assisted Microscopy, 10(4), pp. 151-162. (doi: 10.1023/A:1023482003483)
Daly, C.J. , Milligan, C.M., Milligan, G. , Mackenzie, J.F. and McGrath, J.C. (1998) Cellular localization and pharmacological characterization of functioning alpha-1 adrenoceptors by fluorescent ligand binding and image analysis reveals identical binding properties of clustered and diffuse populations of receptors. Journal of Pharmacology and Experimental Therapeutics, 286(2), pp. 984-990.
Daly, C.J. , Cotecchia, S. and McGrath, J.C. (1998) Low frequency electrical field stimulation elicits responses in segments of mouse tail artery which are slower in alpha1B-knockout mice than in control mice. Naunyn-Schmiedeberg's Archives of Pharmacology, 358(S2), P6.40.
Giummelly, P., Colas, T., Atkinson, J., Robert, A., Daly, C.J. , Luo, D. and McGrath, J.C. (1998) Fluorescence of the medial aortic elastic lamella in elastocalcinotic rats. Naunyn-Schmiedeberg's Archives of Pharmacology, 358(S1), P37.36.
Luo, D., Daly, C.J. , Mackenzie, J.F., McGrory, S.P., Robert, A. and McGrath, J.C. (1998) 3D remodelling of alpha1-adrenoceptors in live cells using a fluorescent ligand, QAPB and confocal laser scanning microscopy. Naunyn-Schmiedeberg's Archives of Pharmacology, 358(S2), P6.44.
Mackenzie, J.F., Daly, C.D. and McGrath, J.C. (1998) Comparison and validation of human a1-adrenoceptor binding characteristics on live, whole cells using radioligand binding and confocal laser scanning microscopic techniques. Naunyn-Schmiedeberg's Archives of Pharmacology, 358(S2), P6.45.
Pediani, J.D. , Mackenzie, J.F., Daly, C.J. and McGrath, J.C. (1998) Functional pharmacological properties of the cloned bovine a 1a-adrenoceptor (a 1a-AR) stably expressed in rat-1 fibroblasts. Naunyn-Schmiedeberg's Archives of Pharmacology, 358(Supp.2), p. 646.
Pediani, J. , Mackenzie, J.F., Daly, C. and McGrath, J. (1998) Comparison of functional and binding pharmacological properties of the cloned bovine a 1a-adrenoceptor (a 1a-AR) stably expressed in rat-1 fibroblasts. Naunyn-Schmiedeberg's Archives of Pharmacology, 358(S2), P6.47.
Robert, A., Daly, C.J. , Luo, D., Montgomery, I. and McGrath, J.C. (1998) Decrease of the medial carotid elastin componentin rabbit ligated coronary heart failure model. Naunyn-Schmiedeberg's Archives of Pharmacology, 358(S2), P57.22.
Daly, C.J., , de la Rue, S.A., Luo, D. and McGrath, J.C. (1997) 3D-distribution of a-adrenoceptors in blood vessel lack of staining on endothelial cells. Journal of Vascular Research, 34(Sup 1), p. 34. (doi: 10.1159/000317489)
McGrath, J. C. , Arribas, S. and Daly, C. J. (1996) Fluorescent ligands for the study of receptors. Trends in Pharmacological Sciences, 17(11), pp. 393-399. (doi: 10.1016/S0165-6147(96)40004-9)
Arribas, S. M., Gordon, J. F., Daly, C. J. , Dominiczak, A. F. and McGrath, J. C. (1996) Confocal microscopic characterization of a lesion in a cerebral vessel of the stroke-prone spontaneously hypertensive rat. Stroke, 27(6), pp. 1118-1123. (doi: 10.1161/01.STR.27.6.1118)
McGrath, J. and Daly, C. (1996) Functional antagonism and receptor-induced fluorescence in rat anococcygeus. FASEB Journal, 10(3), p. 2448.
McGrath, J.C. , Arribas, S., Daly, C.J. and Gordon, J.F. (1995) Confocal microscopy for structure and realtime pharmacology in blood vessels. Journal of Human Hypertension, 9(8), pp. 645-647.
McGrath, J.C. et al. (1995) The relationship between the adrenoceptor and nonadrenoceptor-mediated effects of imidazoline- and imidazole-containing compounds. Annals of the New York Academy of Sciences, 763(1), pp. 591-605. (doi: 10.1111/j.1749-6632.1995.tb32454.x)
Arribas, S., Daly, C. , Dominiczak, A. and McGrath, J. (1995) Reduced vasodilator responses to noradrenaline correlates with decreased density of -adrenoceptor flurophore binding in the basilar artery from old WKY rats. Methods and Finding in Experimental and Clinical Pharmacology, 17, CO30.
McGrath, J. and Daly, C. (1995) Viewing adrenoceptors; past, present, and future; commentary and a new technique. Pharmacology Communications, 1(6), pp. 269-279.
Arribas, S., Gordon, J.F., Daly, C. , Davidson, A., Dominiczak, A. and McGrath, J.C. (1994) Vascular smooth muscle rearrangement and impaired contractions in basilar artery of the stroke-prone spontaneously hypertensive rat. Journal of Hypertension, 12(11), p. 1319.
Daly, C.J. , Gordon, J.F. and McGrath, J.C. (1994) The use of confocal microscopy for the study of resistance artery structure and function. Journal of Vascular Research, 31(Sup 1), p. 10. (doi: 10.1159/000159068)
Macmillan, J.M., Daly, C.J. and McGrath, J.C. (1994) The innervation and alpha-adrenoceptor profile of rabbit isolated dorsal cutaneous and sub-cutaneous resistance arteries. Journal of Vascular Research, 31(Sup 1), p. 30. (doi: 10.1159/000317452)
Gordon, J.F., Baird, M., Daly, C.J. and McGrath, J.C. (1992) Endogenous nitric oxide modulates sympathetic neuroeffector transmission in the isolated rabbit lateral saphenous vein. Journal of Cardiovascular Pharmacology, 20(Sup 12), S68-S71.
MacDonald, A., Daly, C.J. , Bulloch, J.M. and McGrath, J.C. (1992) Contributions of α1-adrenoceptors, α2-adrenoceptors and P2x-purinoceptors to neurotransmission in several rabbit isolated blood vessels: role of neuronal uptake and autofeedback. British Journal of Pharmacology, 105(2), pp. 347-354. (doi: 10.1111/j.1476-5381.1992.tb14257.x)
Daly, C.J. , Gordon, J.F. and McGrath, J.C. (1992) Endogenous nitric oxide modulates sympathetic neuroeffector transmission in the rabbit isolated lateral saphenous vein. Journal of Vascular Research, 29(2), p. 99. (doi: 10.1159/000317442)
Daly, C.J. , Gordon, J.F. and McGrath, J.C. (1992) The use of fluorescent nuclear dyes for the study of blood vessel structure and function: novel applications of existing techniques. Journal of Vascular Research, 29(1), pp. 41-48. (doi: 10.1159/000158930)
Daly, C.J. , MacLean, M.R. and McGrath, J.C. (1992) Electrical field stimulation of rabbit isolated cutaneous and pulmonary microvessels demonstrates the diversity of innervation within the microcirculation. British Journal of Pharmacology, 107(S2), 453P. (doi: 10.1111/j.1476-5381.1992.tb16283.x)
Bulloch, J.M., MacDonald, A., Daly, C.J. and McGrath, J.C. (1991) Effect of cocaine on neurotransmission in rabbit isolated blood vessels. Fundamental and Clinical Pharmacology, 5(5), p. 454. (doi: 10.1111/j.1472-8206.1991.tb00732.x)
Dunn, W.R., Daly, C.J. , McGrath, J.C. and Wilson, V.G. (1991) A comparison of the effects of angiotensin II and Bay K 8644 on responses to noradrenaline mediated via postjunctional α1-and α2-adrenoceptors in rabbit isolated blood vessels. British Journal of Pharmacology, 103(2), pp. 1475-1483. (doi: 10.1111/j.1476-5381.1991.tb09814.x)
Dunn, W.R., Daly, C.J. , McGrath, J.C. and Wilson, V.G. (1991) The effects of nifedipine on alpha 2-adrenoceptor-mediated contractions in several isolated blood vessels from the rabbit. British Journal of Pharmacology, 103(2), pp. 1493-1499. (doi: 10.1111/j.1476-5381.1991.tb09816.x)
Daly, C. , Gordon, J.F. and McGrath, J. (1991) A fluorescence image analysis method for the study of smooth muscle cell interaction within the vascular wall of small blood vessels. Journal of Vascular Research, 28(4), p. 281. (doi: 10.1159/000158878)
Daly, C.J. , Gordon, J.F. and McGrath, J.C. (1991) Assessment of cell viability within the wall of rat mesenteric arteries. Journal of Vascular Research, 28(4), p. 282. (doi: 10.1159/000158878)
Daly, C.J. , Gordon, J.F., McGrath, J.C. and Spedding, M. (1991) Quantification of experimentally induced ischaemic damage to smooth muscle cell membranes within the wall of resistance arteries. Blood Vessels, 28(4), p. 281. (doi: 10.1159/000158878)
Bulloch, J.M., Daly, C.J. , Dunn, W.R., MacDonald, A. and McGrath, J.C. (1990) α,β-methylene ATP can potentiate as well as inhibit nerve mediated responses of rabbit blood vessels and guinea pig vas deferens. European Journal of Pharmacology, 183(2), pp. 543-544. (doi: 10.1016/0014-2999(90)93450-5)
Daly, C.J. , McGrath, J.C. and Wilson, V.G. (1990) Activation of venous alpha2-adrenoceptors by UK-14304 in the presence of low extracellular Ca2+ is associated with an initial transient contraction. British Journal of Pharmacology, 100(S1), 465P. (doi: 10.1111/j.1476-5381.1990.tb16988.x)
MacDonald, A., Daly, C.J. , Wilson, V.G. and McGrath, J.C. (1990) Effects of prejunctional a-adrenoceptor activation on neurotransmission in the rabbit saphenous artery. British Journal of Pharmacology, 99(S1), 53P. (doi: 10.1111/j.1476-5381.1990.tb16587.x)
Daly, C.J. , Dunn, W.R., McGrath, J.C. , Miller, D.J. and Wilson, V.G. (1990) An examination of the sources of calcium for contractions mediated by postjunctional α1- and α2-adrenoceptors in several blood vessels isolated from the rabbit. British Journal of Pharmacology, 99(2), pp. 253-260. (doi: 10.1111/j.1476-5381.1990.tb14690.x)
Daly, C.J. , McGrath, J.C. and Wilson, V.G. (1990) Angiotensin II selectively potentiates "innervated" post-junctional alpha2-adrenoceptors in the rabbit isolated plantaris vein. Journal of Autonomic Pharmacology, 10(1), 17P. (doi: 10.1111/j.1474-8673.1990.tb00002.x)
Daly, C.J. , McGrath, J.C. and Wilson, V.G. (1990) Ca++ coupling mechanisms and veinous alpha2-adrenoceptors - the effect of angiotensin II. Journal of Autonomic Pharmacology, 10(1), 16P. (doi: 10.1111/j.1474-8673.1990.tb00002.x)
Daly, C.J. , Gordon, J., Boyle, F.C., Gillespie, J.S., McGrath, J.C. , Moss, V.A. and Spurway, N.C. (1990) Fluorescent myography: the analysis of isolated vascular smooth muscle cells of the rat labelled with bisbenzamide during vasoconstriction. Journal of Physiology, 429(Suppl.), 11P.
Gordon, J.F., Daly, C.J. , Boyle, F.C., Kusel, J.R., Gillespie, J.S. and McGrath, J.C. (1990) A simple fluorescence-based cell viability assay for use in rat blood vessels in vitro. Journal of Physiology, 429(s), 10P.
Melville, C.A. , Trainor, M., McGrath, J.C. , Daly, C. , O'Dowd, J.J. and Miller, D.J. (1990) Carnosine shows alpha-adrenoceptor agonist and antagonist properties in saphenous vein isolated from rabbit. Journal of Physiology, 427(Suppl.), 29P.
McGrath, J.C. , Bulloch, J., Daly, C.J. and MacDonald, A. (1990) Contributions of different receptors to vasoconstrictor co-transmission in rabbit isolated arteries and veins. Journal of Vascular Research, 27(1), pp. 28-63. (doi: 10.1159/000158794)
Daly, C.J. , Dunn, W.R., McGrath, J. and Wilson, V.G. (1989) A Comparison of the actions of BAY K-8644 and angiotensin II on extracellular calcium-dependent contractile responses mediated by postjunctional alpha2-adrenoceptors. Annals of the New York Academy of Sciences, 560, pp. 440-443. (doi: 10.1111/j.1749-6632.1989.tb24131.x)
Daly, C.J. , McGrath, J.C. and Wilson, V.G. (1989) Preliminary evidence for the release of cellular-bound calcium by post-junctional alpha2-adrenoceptors in the rabbit isolated ear vein. Journal of Physiology, 414(Suppl.), 57P.
McGrath, J.C. , Daly, C.J. , Dunn, W.R., MacLennan, S.J., Macmillan, J.B., Templeton, A.G.B. and Wilson, V.G. (1989) Physiological modulation of alpha-adreno- and 5HT- receptor expression in blood vessels. Journal of Vascular Medicine and Biology, 1, p. 187.
Wilson, V.G., McGrath, J.C. and Daly, C.J. (1989) Does basal release of an endothelium-derived relaxing factor modulate alpha-adrenoceptor function in the rabbit saphenous vein? Journal of Vascular Medicine and Biology, 1, p. 211.
Bulloch, J.M., Daly, C.J. , MacDonald, A., McGrath, J.C. and Wilson, V.G. (1988) The effect of nifedipine on nerve-mediated responses of blood vessels in vitro and in vivo. British Journal of Pharmacology, 95(S1), 563P. (doi: 10.1111/j.1476-5381.1988.tb16614.x)
Daly, C.J. , Dunn, W.R., McGrath, J.C. and Wilson, V.G. (1988) An attempt at selective protection from phenoxybenzamine of postjunctional α-adrenoceptor subtypes mediating contractions to noradrenaline in the rabbit isolated saphenous vein. British Journal of Pharmacology, 95(2), pp. 501-511. (doi: 10.1111/j.1476-5381.1988.tb11670.x)
Daly, C.J. , Dunn, W.R., McGrath, J.C. and Wilson, V.G. (1988) Effect of angiotensin II on responses to noradrenaline mediated via post-junctional alpha-1 and alpha2-adrenoceptors in isolated rabbit blood vessels. British Journal of Pharmacology, 95(S1), 475P-589P. (doi: 10.1111/j.1476-5381.1988.tb16614.x)
Daly, C.J. , McGrath, J.C. and Wilson, V.G. (1988) An examination of the postjunctional α-adrenoceptor subtypes for (−)-noradrenaline in several isolated blood vessels from the rabbit. British Journal of Pharmacology, 95(2), pp. 473-484. (doi: 10.1111/j.1476-5381.1988.tb11668.x)
Daly, C.J. , McGrath, J.C. and Wilson, V.G. (1988) Pharmacological analysis of postjunctional α-adrenoceptors mediating contractions to (−)-noradrenaline in the rabbit isolated lateral saphenous vein can be explained by interacting responses to simultaneous activation of α1-and α2-adrenoceptors. British Journal of Pharmacology, 95(2), pp. 485-500. (doi: 10.1111/j.1476-5381.1988.tb11669.x)
Daly, C.J. , McGrath, J.C. and Wilson, V.G. (1988) Evidence that the population of postjunctional-adrenoceptors mediating contraction of smooth muscle in the rabbit isolated ear vein is predominantly α2. British Journal of Pharmacology, 94(4), pp. 1085-1090. (doi: 10.1111/j.1476-5381.1988.tb11626.x)
Daly, C.J. , McGrath, J.C. and Wilson, V.G. (1987) α-Adrenoceptor-mediated contractions in the rabbit saphenous vein : the influence of endothelial cells. British Journal of Pharmacology, 92(S1), 776P. (doi: 10.1111/j.1476-5381.1987.tb16603.x)
Daly, C.J. , McGrath, J.C. and Wilson, V.G. (1987) Isolation of post-junctional alpha2-adrenoceptors in the rabbit isolated saphenous vein with phenoxybenzamine. British Journal of Pharmacology, 92(S1), 775P. (doi: 10.1111/j.1476-5381.1987.tb16603.x)
Dainty, I.A., Daly, C.J. , McGrath, J.C. , Sinclair, J. and Spedding, M. (1987) Measurement and analysis of analogue signals from a Linseis chart recorder using a BBC microcomputer. British Journal of Pharmacology, 91(Suppl.), p. 506.
Daly, C.J. , McGrath, J.C. and Wilson, V.G. (1987) Post-junctional alpha-adrenoceptors subtype(s) for(-)-noradrenaline in the rabbit isolated saphenous vein. British Journal of Pharmacology, 91(Suppl.), p. 397.
Daly, C.J. , McGrath, J.C. , Muir, A.G.H. and O'Brien, J.W. (1985) Ca++-dependence of noradrenaline-induced contraction in rat aortic smooth muscle. British Journal of Pharmacology, 86(S2), 659P-815P. (doi: 10.1111/j.1476-5381.1985.tb14737.x)
Book Sections
McGrath, J. C. and Daly, C. J. (2006) Use of fluorescent ligands and receptors to visualize adrenergic receptors. In: Perez, D. M. (ed.) The Adrenergic Receptors: In the 21st Century. Series: The receptors, III. Humana Press, pp. 151-172. ISBN 9781588294234 (doi: 10.1385/1-59259-931-1:151)
Arriba, S.M., Daly, C.J. , Gordon, J.F. and McGrath, J.C. (1994) Confocal myography: applications for the study of resistance arteries. In: Halpern, W., Bevan, J.A., Brayden, J., Dustan, H. and Nelson, M. (eds.) The Resistance Arteries: Integration of the Regulatory Pathways. Series: Experimental biology and medicine (26). Humana Press: New York, NY, pp. 259-264. ISBN 9781617370083
Daly, C.J. , Gordon, J.F. and McGrath, J.C. (1991) Fluorescence image analysis methods for the study of smooth muscle cell interaction within the vascular wall of small blood vessels. In: Mulvany, M. J. (ed.) Resistance Arteries, Structure and Function. Excerpta Medica: Amsterdam, pp. 339-343. ISBN 9780444891938
Conference or Workshop Item
Stevenson, C., Methven, L., McLachlan, E., Daly, C. and McGrath, J.C. (2011) Investigating the Role of α2-adrenoceptors in Tail Artery of Wild Type Mice and Mice Lacking α1-adrenoceptors (α1-null). Vascular and Smooth Muscle Physiology Themed Meeting, Edinburgh, UK, 06-08 Dec 2011.
Daly, C.J. , Wallace, G., White, K., Chris, H., Irving, A. and McGrath, J.C. (2008) Visualisation of Vascular Cannabinoid Receptors and their Potential Interaction with α1-adrenergic Receptors. Proceedings of the Physiological Society 13, King's College London, 2008.
Ali, Z., McGrath, J.C. and Daly, C.J. (2004) Adrenergic and Serotonergic Synergism in the Mouse Thoracic Aorta. University of Glasgow 2004, 2004.
McBride, M., Daly, C.J. , McGrath, J.C. and Malekzadeh-Shafaroudi, M. (2004) A Study of α2-adrenoceptor-mediated Vasodilatation in Mesenteric Resistance Arteries From Transgenic Mice. University of Glasgow 2004, 2004.
Ali, Z., McGrath, J.C. , Tsujimoto, G. and Daly, C.J. (2003) Inhibition of 5-hydroxytryptamine-mediated Contraction by α1-adrenoceptor Antagonist in Mouse Thoracic Aorta. XXXII Congress of the Spanish Society of Physiological Sciences International Joint Meeting with The Physiological Society, Puerto de la Cruz, Tenerife, 13-17 Feb 2003.
Briones, A., González, J. M., Somoza, B., Giraldo, J., Daly, C. , McGrath, I. , Vila, E., González, C. and Arribas, S. M. (2003) Relationship Between Elastin Organisation and Structural and Mechanical Abnormalities in Resistance Arteries From Spontaneously Hypertensive Rats. XXXII Congress of the Spanish Society of Physiological Sciences International Joint Meeting with The Physiological Society, Puerto de la Cruz, Tenerife, 13-17 Feb 2003.
McBride, M., Daly, C.J. , Tsujimoto, G. and McGrath, J.C. (2003) Removal of the α1B-adrenoceptor Uncovers an α1D Component in Mesenteric Resistance Arteries. XXXII Congress of the Spanish Society of Physiological Sciences International Joint Meeting with The Physiological Society, Puerto de la Cruz, Tenerife, 13-17 Feb 2003.
Conference Proceedings
Daly, C.J. , Wallace, G., White, K., Henstridge, C., Irving, A. and McGrath, J.C. (2008) Visualisation of Vascular Cannabinoid Receptors and their Potential Interaction with alpha1-adrenergic Receptors. In: Vascular and Smooth Muscle Physiology. Themed Meeting of the Physiological Society, King's College, London, December 2008,
Morton, J.S., Daly, C.J. , McGrath, J.C. and Jackson, V.M. (2005) Development of an in vitro method to study vaginal arteries using myography. In: University of Newcastle Winter Meeting, Newcastle, UK, 2005,
McBride, M., Daly, C. and McGrath, J. (2002) Contractile responses to UK 14304 in the mouse tail artery differ when the drug is administered cumulatively or non-cumulatively. In: 7th Annual Meeting of the European Council for Blood Pressure and Cardiovascular Research (ECCR), Seeheim, Germany, 11-13 Oct 2002,
Daly, C.J. , Vila, E., Arribas, S.M., Pagakis, S., Thebault, B., Maddison, J., Pederson, J. and McGrath, J.C. (2000) 3-dimensional analysis of vascular structure, function & receptor distribution using confocal laser scanning microscopy. In: 10th Porto Meeting on Adrenergic Mechanisms, Porto, Portugal, 25-27 Sep 2000,
Granitsioti, P., Daly, C. , Kirk, D. and McGrath, J. (2000) Physiology of the human vas deferens; Clinical importance. In: 10th Porto Meeting on Adrenergic Mechanisms, Porto, Portugal, 25-27 Sept 2000,
Mackenzie, J.F., Pediani, J. , Daly, C. , Deighan, C. and McGrath, J. (2000) Fluorescent ligand binding to alpha1-adrenoceptors in murine hepatocytes. In: 10th Porto Meeting on Adrenergic Mechanisms, Porto, Portugal, 25-27 Sept 2000, P2.
Shang, C., Daly, C. , McGrath, J. and Barker, J. (2000) Neural network based classification of cell images via estimation of fractal dimensions. In: International Conference on Artificial Neural Networks in Medicine and Biology, Goteburg, Sweden, 13-16 May 2000, pp. 111-116. (doi: 10.1007/978-1-4471-0513-8_15)
McGrath, J.C. , Mackenzie, J.F. and Daly, C.J. (1999) Sub-cellular localisation of alpha1-adrenoceptors in live cells and tissues. In: British Pharmacological Societ Joint Spring Meeting with Portuguese Pharmacological Society, Porto, Portugal, 8-9 Apr 1999, 133P.
Robert, A., Daly, C.J. and McGrath, J.C. (1998) Decrease of in vitro carotid compliance in rabbit heart failure model. In: Heart Failure Update, Glasgow, UK, 1998, p. 8.
Arribas, S.M., Gordon, J.F., Daly, C.J. , Davidson, A., Dominiczak, A. and McGrath, J.C. (1995) Structural and functional alterations in the basilar artery from stroke prone spontaneously hypertensive rats. In: 7th European Meeting on Hypertension, Milan, Italy, 9-12 Jun 1995, p. 12.
Daly, C.J. , Gordon, J.F. and McGrath, J.C. (1993) Dimensional analysis of smooth muscle cell reactivity within the rat resistance artery using confocal microscopy. In: XXXII Congress of the International Union of Physiological Sciences, Glasgow, UK, 1-6 Aug 1993,
Daly, C.J. , Gordon, J.F. and McGrath, J.C. (1993) Observation of vasodilatation in small arteries with confocal microscopy. In: XXXII Congress of the International Union of Physiological Sciences, Glasgow, UK, 1-6 Aug 1993,
Gordon, J.F., Daly, C.J. and McGrath, J.C. (1993) Analysis of rat resistance artery structure in pressurised vessels using confocal microscopy. In: XXXII Congress of the International Union of Physiological Sciences, Glasgow, UK, 1-6 Aug 1993,
McGrath, J.C. , Daly, C.J. , Dunn, W.R., MacDonald, A., Macmillan, J.B., Templeton, A.G.B. and Wilson, V.G. (1989) Variation in participation of postjunctional alpha1 and alpha2-adrenoceptors and P2y purinoceptors in vascular sympathetic co-transmission: modulation by drugs and hormones. In: XXXIst International Congress of Physiological Sciences, Helsinki, Finland, 9-14 Jul 1989, p. 4376.
Dainty, I.A., Daly, C.J. , McGrath, J.C. , Sinclair, J. and Spedding, M. (1987) A simple, inexpensive method of collection, storage and analysis of data for the BBC microcomputer. In: Glasgow Meeting of the Physiological Society, Glasgow, UK, 19-20 Jun 1987, p. 22.
