Dr Fiona Leiper
- Research Associate (Cardiovascular & Metabolic Health)
telephone:
0141 3302757
email:
Fiona.Leiper@glasgow.ac.uk
pronouns:
She/her/hers
https://orcid.org/0000-0001-6681-681XResearch interests
Publications
2024
Hanson Ng, Y. Y. et al. (2024) Asymmetric dimethylarginine enables depolarizing spikes and vasospasm in mesenteric and coronary resistance arteries. Hypertension, 81(4), pp. 764-775. (doi: 10.1161/HYPERTENSIONAHA.123.22454) (PMID:38226470) (PMCID:PMC10956675)
2020
Dowsett, L. , Higgins, E., Alanazi, S., Alshuwayer, N. A., Leiper, F. C. and Leiper, J. (2020) ADMA: A key player in the relationship between vascular dysfunction and inflammation in atherosclerosis. Journal of Clinical Medicine, 9(9), 3026. (doi: 10.3390/jcm9093026) (PMID:32962225) (PMCID:PMC7563400)
2015
Rousset, C. I., Leiper, F. C. , Kichev, A., Gressens, P., Carling, D., Hagberg, H. and Thornton, C. (2015) A dual role for AMP-activated protein kinase (AMPK) during neonatal hypoxic-ischaemic brain injury in mice. Journal of Neurochemistry, 133(2), pp. 242-252. (doi: 10.1111/jnc.13034) (PMID:25598140) (PMCID:PMC4855681)
2011
Mayer, F. V. et al. (2011) ADP regulates SNF1, the saccharomyces cerevisiae homolog of AMP-activated protein kinase. Cell Metabolism, 14(5), pp. 707-714. (doi: 10.1016/j.cmet.2011.09.009) (PMID:22019086) (PMCID:PMC3241989)
2007
Dranchak, P. K., Leiper, F. C. , Valberg, S. J., Piercy, R. J., Carling, D., McCue, M. E. and Mickelson, J. R. (2007) Biochemical and genetic evaluation of the role of AMP-activated protein kinase in polysaccharide storage myopathy in Quarter Horses. American Journal of Veterinary Research, 68(10), pp. 1079-1084. (doi: 10.2460/ajvr.68.10.1079) (PMID:17916014)
Xiao, B. et al. (2007) Structural basis for AMP binding to mammalian AMP-activated protein kinase. Nature, 449(7161), pp. 496-500. (doi: 10.1038/nature06161) (PMID:17851531)
2003
Hong, S.-P., Leiper, F.C. , Woods, A., Carling, D. and Carlson, M. (2003) Activation of yeast Snf1 and mammalian AMP-activated protein kinase by upstream kinases. Proceedings of the National Academy of Sciences of the United States of America, 100(15), pp. 8839-8843. (doi: 10.1073/pnas.1533136100) (PMID:12847291) (PMCID:PMC166400)
Woods, A., Johnstone, S. R., Dickerson, K., Leiper, F. C. , Fryer, L. G.D., Neumann, D., Schlattner, U., Wallimann, T., Carlson, M. and Carling, D. (2003) LKB1 Is the upstream kinase in the AMP-activated protein kinase cascade. Current Biology, 13(22), pp. 2004-2008. (doi: 10.1016/j.cub.2003.10.031) (PMID:14614828)
2002
Brandão, R.L. et al. (2002) Evidence for involvement of Saccharomyces cerevisiae protein kinase C in glucose induction of HXTgenes and derepression of SUC2. FEMS Yeast Research, 2(2), pp. 93-102. (doi: 10.1111/j.1567-1364.2002.tb00074.x) (PMID:12702297)
Salgado, A.P.C., Schuller, D., Casal, M., Leão, C., Leiper, F.C. , Carling, D., Fietto, L.G., Trópia, M.J., Castro, I.M. and Brandão, R.L. (2002) Relationship between protein kinase C and derepression of different enzymes. FEBS Letters, 532(3), pp. 324-332. (doi: 10.1016/S0014-5793(02)03695-5) (PMID:12482587)
1999
Smith, F. C. , Davies, S. P., Wilson, W. A., Carling, D. and Hardie, D. G. (1999) The SNF1 kinase complex from Saccharomyces cerevisiae phosphorylates the transcriptional repressor protein Mig1p in vitro at four sites within or near regulatory domain 1. FEBS Letters, 453(1-2), pp. 219-223. (doi: 10.1016/S0014-5793(99)00725-5) (PMID:10403407)
1997
Carling, D., Woods, A., Thornton, C., Cheung, P.C., Leiper, F.C. , Ponticos, M. and Stein, S.C. (1997) Molecular characterization of the AMP-activated protein kinase and its role in cellular metabolism. Biochemical Society Transactions, 25(4), pp. 1224-1228. (doi: 10.1042/bst0251224) (PMID:9449980)
Munn, E. A., Smith, T. S., Smith, H., James, F. M., Smith, F. C. and Andrews, S. J. (1997) Vaccination against Haemonchus contortus with denatured forms of the protective antigen H11. Parasite Immunology, 19(6), pp. 243-248. (doi: 10.1046/j.1365-3024.1997.d01-205.x) (PMID:9364553)
1996
Woods, A., Cheung, P. C. F., Smith, F. C. , Davison, M. D., Scott, J., Beri, R. K. and Carling, D. (1996) Characterization of AMP-activated protein kinase beta and gamma subunits. Journal of Biological Chemistry, 271(17), pp. 10282-10290. (doi: 10.1074/jbc.271.17.10282) (PMID:8626596)
Articles
Hanson Ng, Y. Y. et al. (2024) Asymmetric dimethylarginine enables depolarizing spikes and vasospasm in mesenteric and coronary resistance arteries. Hypertension, 81(4), pp. 764-775. (doi: 10.1161/HYPERTENSIONAHA.123.22454) (PMID:38226470) (PMCID:PMC10956675)
Dowsett, L. , Higgins, E., Alanazi, S., Alshuwayer, N. A., Leiper, F. C. and Leiper, J. (2020) ADMA: A key player in the relationship between vascular dysfunction and inflammation in atherosclerosis. Journal of Clinical Medicine, 9(9), 3026. (doi: 10.3390/jcm9093026) (PMID:32962225) (PMCID:PMC7563400)
Rousset, C. I., Leiper, F. C. , Kichev, A., Gressens, P., Carling, D., Hagberg, H. and Thornton, C. (2015) A dual role for AMP-activated protein kinase (AMPK) during neonatal hypoxic-ischaemic brain injury in mice. Journal of Neurochemistry, 133(2), pp. 242-252. (doi: 10.1111/jnc.13034) (PMID:25598140) (PMCID:PMC4855681)
Mayer, F. V. et al. (2011) ADP regulates SNF1, the saccharomyces cerevisiae homolog of AMP-activated protein kinase. Cell Metabolism, 14(5), pp. 707-714. (doi: 10.1016/j.cmet.2011.09.009) (PMID:22019086) (PMCID:PMC3241989)
Dranchak, P. K., Leiper, F. C. , Valberg, S. J., Piercy, R. J., Carling, D., McCue, M. E. and Mickelson, J. R. (2007) Biochemical and genetic evaluation of the role of AMP-activated protein kinase in polysaccharide storage myopathy in Quarter Horses. American Journal of Veterinary Research, 68(10), pp. 1079-1084. (doi: 10.2460/ajvr.68.10.1079) (PMID:17916014)
Xiao, B. et al. (2007) Structural basis for AMP binding to mammalian AMP-activated protein kinase. Nature, 449(7161), pp. 496-500. (doi: 10.1038/nature06161) (PMID:17851531)
Hong, S.-P., Leiper, F.C. , Woods, A., Carling, D. and Carlson, M. (2003) Activation of yeast Snf1 and mammalian AMP-activated protein kinase by upstream kinases. Proceedings of the National Academy of Sciences of the United States of America, 100(15), pp. 8839-8843. (doi: 10.1073/pnas.1533136100) (PMID:12847291) (PMCID:PMC166400)
Woods, A., Johnstone, S. R., Dickerson, K., Leiper, F. C. , Fryer, L. G.D., Neumann, D., Schlattner, U., Wallimann, T., Carlson, M. and Carling, D. (2003) LKB1 Is the upstream kinase in the AMP-activated protein kinase cascade. Current Biology, 13(22), pp. 2004-2008. (doi: 10.1016/j.cub.2003.10.031) (PMID:14614828)
Brandão, R.L. et al. (2002) Evidence for involvement of Saccharomyces cerevisiae protein kinase C in glucose induction of HXTgenes and derepression of SUC2. FEMS Yeast Research, 2(2), pp. 93-102. (doi: 10.1111/j.1567-1364.2002.tb00074.x) (PMID:12702297)
Salgado, A.P.C., Schuller, D., Casal, M., Leão, C., Leiper, F.C. , Carling, D., Fietto, L.G., Trópia, M.J., Castro, I.M. and Brandão, R.L. (2002) Relationship between protein kinase C and derepression of different enzymes. FEBS Letters, 532(3), pp. 324-332. (doi: 10.1016/S0014-5793(02)03695-5) (PMID:12482587)
Smith, F. C. , Davies, S. P., Wilson, W. A., Carling, D. and Hardie, D. G. (1999) The SNF1 kinase complex from Saccharomyces cerevisiae phosphorylates the transcriptional repressor protein Mig1p in vitro at four sites within or near regulatory domain 1. FEBS Letters, 453(1-2), pp. 219-223. (doi: 10.1016/S0014-5793(99)00725-5) (PMID:10403407)
Carling, D., Woods, A., Thornton, C., Cheung, P.C., Leiper, F.C. , Ponticos, M. and Stein, S.C. (1997) Molecular characterization of the AMP-activated protein kinase and its role in cellular metabolism. Biochemical Society Transactions, 25(4), pp. 1224-1228. (doi: 10.1042/bst0251224) (PMID:9449980)
Munn, E. A., Smith, T. S., Smith, H., James, F. M., Smith, F. C. and Andrews, S. J. (1997) Vaccination against Haemonchus contortus with denatured forms of the protective antigen H11. Parasite Immunology, 19(6), pp. 243-248. (doi: 10.1046/j.1365-3024.1997.d01-205.x) (PMID:9364553)
Woods, A., Cheung, P. C. F., Smith, F. C. , Davison, M. D., Scott, J., Beri, R. K. and Carling, D. (1996) Characterization of AMP-activated protein kinase beta and gamma subunits. Journal of Biological Chemistry, 271(17), pp. 10282-10290. (doi: 10.1074/jbc.271.17.10282) (PMID:8626596)