Dr Eilidh MacDonald

  • Research Fellow (Cardiovascular & Metabolic Health)

Biography

Eilidh is a Postdoctoral Research Fellow in the School of Cardiovascular and Metabolic Health at the University of Glasgow. Eilidh comes from Canada, which is also where she completed her PhD at Dalhousie University in Halifax, Nova Scotia under the supervision of Prof Alex Quinn. Her work investigated intrinsic regulation of the heart’s natural pacemaker and the effects of mechano-electric interactions on heart rhythm. During this time, she was awarded a travel grant which allowed her to spend a year at the Institute for Experimental Cardiovascular Medicine working under the supervision of Prof Peter Kohl.

In January 2021 Eilidh moved to Glasgow to work as a postdoc with Prof Chris Loughrey investigating cardiac dysfunction. Specifically, she has been working to understand mechanisms by which cardiac disease leads to changes in heart architecture and function, and how this adverse cardiac remodelling leads to heart failure and arrhythmia. She is fascinated by the heart and loves working to understand the complex and intricate ways in which it self-regulates both in health and disease in order to perform its very simple (yet essential to life) task – to pump.

Eilidh is a member of the International Society for Heart Research, the Physiological Society, and the British Society for Cardiovascular Research. In 2022 she was awarded the British Society for Cardiovascular Research Early Career Researcher Award and in 2023 was selected for a Journal of Physiology Editorial Board Fellowship.

Research interests

Research Theme: Cardiac Diseases

Research groups

Publications

List by: Type | Date

Jump to: 2025 | 2023 | 2022 | 2021 | 2020 | 2018 | 2017
Number of items: 10.

2025

Elbassioni, A. A. M. et al. (2025) Targeting Runx1 protects against heart failure with preserved ejection fraction. bioRxiv, (doi: 10.1101/2025.01.24.634831)

McIntosh, B., Elbassioni, A., Raheem, A., MacDonald, E. A. , Nicklin, S. A. , Koay, Y. C., Cameron, E. R. , Loughrey, C. M. and O'Sullivan, J. F. (2025) Optimized protocols for commonly-used murine models of heart failure with preserved ejection fraction. bioRxiv, (doi: 10.1101/2025.01.22.634221)

2023

Martin, T. P. et al. (2023) Ribonucleicacid interference or small molecule inhibition of Runx1 in the border zone prevents cardiac contractile dysfunction following myocardial infarction. Cardiovascular Research, 119(16), 2663–2671-2663–2671. (doi: 10.1093/cvr/cvad107) (PMID:37433039) (PMCID:PMC10730241)

2022

Martin, T. P. , MacDonald, E. A. , Elbassioni, A. A., Zaeri, A. A. I., O'Toole, D., Nicklin, S. A. , Gray, G. A. and Loughrey, C. M. (2022) Pre-clinical models of myocardial infarction: from mechanism to translation. British Journal of Pharmacology, 179(5), pp. 770-791. (doi: 10.1111/bph.15595) (PMID:34131903)

Stoyek, M. R., MacDonald, E. , Mantifel, M., Baillie, J. S., Selig, B. M., Croll, R. P., Smith, F. M. and Quinn, T. A. (2022) Drivers of sinoatrial node automaticity in zebrafish: comparison with mechanisms of mammalian pacemaker function. Frontiers in Physiology, 13, 818122. (doi: 10.3389/fphys.2022.818122) (PMID:35295582) (PMCID:PMC8919049)

2021

MacDonald, E. A. and Quinn, T. A. (2021) What keeps us ticking? Sinoatrial node mechano-sensitivity: the grandfather clock of cardiac rhythm. Biophysical Reviews, 13(5), pp. 707-716. (doi: 10.1007/s12551-021-00831-8) (PMID:34777615)

2020

MacDonald, E. A. , Madl, J., Greiner, J., Ramadan, A. F., Wells, S. M., Torrente, A. G., Kohl, P., Rog-Zielinska, E. A. and Quinn, T. A. (2020) Sinoatrial node structure, mechanics, electrophysiology and the chronotropic response to stretch in rabbit and mouse. Frontiers in Physiology, 11, 809. (doi: 10.3389/fphys.2020.00809) (PMID:32774307) (PMCID:PMC7388775)

MacDonald, E. A. , Rose, R. A. and Quinn, T. A. (2020) Neurohumoral control of sinoatrial node activity and heart rate: insight from experimental models and findings from humans. Frontiers in Physiology, 11, 170. (doi: 10.3389/fphys.2020.00170) (PMID:32194439) (PMCID:PMC7063087)

2018

MacDonald, E. and Quinn, T. A. (2018) Mechanical Determinants of the Chronotropic Response to Sinoatrial Stretch. Journal of Molecular and Cellular Cardiology 124:91. Meeting Abstract: 2018 ISHR-NAS annual meeting, Halifax, NS, Canada, 29 May - 1 Jun 2018. (doi: 10.1016/j.yjmcc.2018.07.030)

2017

MacDonald, E. A. , Stoyek, M. R., Rose, R. A. and Quinn, T. A. (2017) Intrinsic regulation of sinoatrial node function and the zebrafish as a model of stretch effects on pacemaking. Progress in Biophysics and Molecular Biology, 130(Part B), pp. 198-211. (doi: 10.1016/j.pbiomolbio.2017.07.012) (PMID:28743586)

This list was generated on Wed Mar 26 16:19:30 2025 GMT.
Jump to: Articles | Conference or Workshop Item
Number of items: 10.

Articles

Elbassioni, A. A. M. et al. (2025) Targeting Runx1 protects against heart failure with preserved ejection fraction. bioRxiv, (doi: 10.1101/2025.01.24.634831)

McIntosh, B., Elbassioni, A., Raheem, A., MacDonald, E. A. , Nicklin, S. A. , Koay, Y. C., Cameron, E. R. , Loughrey, C. M. and O'Sullivan, J. F. (2025) Optimized protocols for commonly-used murine models of heart failure with preserved ejection fraction. bioRxiv, (doi: 10.1101/2025.01.22.634221)

Martin, T. P. et al. (2023) Ribonucleicacid interference or small molecule inhibition of Runx1 in the border zone prevents cardiac contractile dysfunction following myocardial infarction. Cardiovascular Research, 119(16), 2663–2671-2663–2671. (doi: 10.1093/cvr/cvad107) (PMID:37433039) (PMCID:PMC10730241)

Martin, T. P. , MacDonald, E. A. , Elbassioni, A. A., Zaeri, A. A. I., O'Toole, D., Nicklin, S. A. , Gray, G. A. and Loughrey, C. M. (2022) Pre-clinical models of myocardial infarction: from mechanism to translation. British Journal of Pharmacology, 179(5), pp. 770-791. (doi: 10.1111/bph.15595) (PMID:34131903)

Stoyek, M. R., MacDonald, E. , Mantifel, M., Baillie, J. S., Selig, B. M., Croll, R. P., Smith, F. M. and Quinn, T. A. (2022) Drivers of sinoatrial node automaticity in zebrafish: comparison with mechanisms of mammalian pacemaker function. Frontiers in Physiology, 13, 818122. (doi: 10.3389/fphys.2022.818122) (PMID:35295582) (PMCID:PMC8919049)

MacDonald, E. A. and Quinn, T. A. (2021) What keeps us ticking? Sinoatrial node mechano-sensitivity: the grandfather clock of cardiac rhythm. Biophysical Reviews, 13(5), pp. 707-716. (doi: 10.1007/s12551-021-00831-8) (PMID:34777615)

MacDonald, E. A. , Madl, J., Greiner, J., Ramadan, A. F., Wells, S. M., Torrente, A. G., Kohl, P., Rog-Zielinska, E. A. and Quinn, T. A. (2020) Sinoatrial node structure, mechanics, electrophysiology and the chronotropic response to stretch in rabbit and mouse. Frontiers in Physiology, 11, 809. (doi: 10.3389/fphys.2020.00809) (PMID:32774307) (PMCID:PMC7388775)

MacDonald, E. A. , Rose, R. A. and Quinn, T. A. (2020) Neurohumoral control of sinoatrial node activity and heart rate: insight from experimental models and findings from humans. Frontiers in Physiology, 11, 170. (doi: 10.3389/fphys.2020.00170) (PMID:32194439) (PMCID:PMC7063087)

MacDonald, E. A. , Stoyek, M. R., Rose, R. A. and Quinn, T. A. (2017) Intrinsic regulation of sinoatrial node function and the zebrafish as a model of stretch effects on pacemaking. Progress in Biophysics and Molecular Biology, 130(Part B), pp. 198-211. (doi: 10.1016/j.pbiomolbio.2017.07.012) (PMID:28743586)

Conference or Workshop Item

MacDonald, E. and Quinn, T. A. (2018) Mechanical Determinants of the Chronotropic Response to Sinoatrial Stretch. Journal of Molecular and Cellular Cardiology 124:91. Meeting Abstract: 2018 ISHR-NAS annual meeting, Halifax, NS, Canada, 29 May - 1 Jun 2018. (doi: 10.1016/j.yjmcc.2018.07.030)

This list was generated on Wed Mar 26 16:19:30 2025 GMT.

Grants

Grants and Awards listed are those received whilst working with the University of Glasgow.

  • Targeting RUNX1 to prevent adverse cardiac remodelling
    Wellcome Trust
    2022 - 2023
     

Supervision


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