Dr Christina Elliott
- Postdoctoral research associate working on joint project(s) (School of Cardiovascular & Metabolic Health)
email:
Christina.Elliott@glasgow.ac.uk
Lab 535, Wolfson Link, Glasgow, G12 8qq
Publications
2024
Lipina, T. et al. (2024) PDE4B missense variant increases susceptibility to post-traumatic stress disorder-relevant phenotypes in mice. Journal of Neuroscience, (Accepted for Publication)
2020
Glennon, E. B. et al. (2020) Bridging integrator 1 protein loss in Alzheimer’s disease promotes synaptic tau accumulation and disrupts tau release. Brain Communications, 2(1), fcaa011. (doi: 10.1093/braincomms/fcaa011) (PMID:32500121) (PMCID:PMC7272218)
2018
Elliott, C. et al. (2018) A role for APP in Wnt signalling links synapse loss with β-amyloid production. Translational Psychiatry, 8, 179. (doi: 10.1038/s41398-018-0231-6) (PMID:30232325) (PMCID:PMC6145937)
Engelhardt, B., Holze, J., Elliott, C. , Baillie, G.S. , Kschischo, M. and Fröhlich, H. (2018) Modelling and mathematical analysis of the M2 receptor-dependent joint signalling and secondary messenger network in CHO cells. Mathematical Medicine and Biology, 35(3), pp. 279-297. (doi: 10.1093/imammb/dqx003) (PMID:28505258)
Sellers, K. J. et al. (2018) Amyloid β synaptotoxicity is Wnt-PCP dependent and blocked by fasudil. Alzheimer's and Dementia, 14(3), pp. 306-317. (doi: 10.1016/j.jalz.2017.09.008) (PMID:29055813) (PMCID:PMC5869054)
Yalla, K. et al. (2018) FBXW7 regulates DISC1 stability via the ubiquitin-proteosome system. Molecular Psychiatry, 23(5), pp. 1278-1286. (doi: 10.1038/mp.2017.138) (PMID:28727686) (PMCID:PMC5984089)
2017
Ashton, N.J., Hye, A., Leckey, C.A., Jones, A.R., Elliott, C. , Wetherell, J.L., Lenze, E.J., Killick, R. and Marchant, N.L. (2017) Plasma REST: a novel candidate biomarker of Alzheimer’s disease is modified by psychological intervention in an at-risk population. Translational Psychiatry, 7, e1148. (doi: 10.1038/tp.2017.113) (PMID:28585932) (PMCID:PMC5537638)
2016
Allan, D., Fairlie-Clarke, K. J., Elliott, C. , Schuh, C., Barnett, S. C. , Lassmann, H., Linnington, C. and Jiang, H.-R. (2016) Role of IL-33 and ST2 signalling pathway in multiple sclerosis: expression by oligodendrocytes and inhibition of myelination in central nervous system. Acta Neuropathologica Communications, 4(1), 75. (doi: 10.1186/s40478-016-0344-1) (PMID:27455844) (PMCID:PMC4960877)
Roscoe, R. B., Elliott, C. , Zarros, A. and Baillie, G. S. (2016) Non-genetic therapeutic approaches to Canavan disease. Journal of the Neurological Sciences, 366, pp. 116-124. (doi: 10.1016/j.jns.2016.05.012) (PMID:27288788)
Al Nimer, F. et al. (2016) Lipocalin-2 is increased in progressive multiple sclerosis and inhibits remyelination. Neurology: Neuroimmunology and Neuroinflammation, 3(1), e191. (doi: 10.1212/NXI.0000000000000191) (PMID:26770997) (PMCID:PMC4708925)
Dachtler, J., Elliott, C. , Rodgers, R. J., Baillie, G. S. and Clapcote, S. J. (2016) Missense mutation in DISC1 C-terminal coiled-coil has GSK3β signaling and sex-dependent behavioral effects in mice. Scientific Reports, 6, 18748. (doi: 10.1038/srep18748) (PMID:26728762) (PMCID:PMC4700527)
Tankou, S. et al. (2016) SUMOylation of DISC1: a potential role in neural progenitor proliferation in the developing cortex. Molecular Neuropsychiatry, 2(1), pp. 20-27. (doi: 10.1159/000444257) (PMID:27525255) (PMCID:PMC4979612)
2015
Lindner, M. et al. (2015) Fibroblast growth factor signalling in multiple sclerosis: inhibition of myelination and induction of pro-inflammatory environment by FGF9. Brain, 138(7), pp. 1875-1893. (doi: 10.1093/brain/awv102) (PMID:25907862) (PMCID:PMC7185739)
Byrne, A. M., Elliott, C. , Hoffmann, R. and Baillie, G. S. (2015) The activity of cAMP-Phosphodiesterase 4D7 (PDE4D7) is regulated by protein kinase A-dependent phosphorylation within its unique N-terminus. FEBS Letters, 589(6), pp. 750-755. (doi: 10.1016/j.febslet.2015.02.004) (PMID:25680530) (PMCID:PMC4346272)
McGirr, A. et al. (2015) Specific inhibition of phosphodiesterase-4B results in anxiolysis and facilitates memory acquisition. Neuropsychopharmacology, 41(4), pp. 1080-1092. (doi: 10.1038/npp.2015.240)
2014
Martin, T. P. , Hortigon-Vinagre, M. P. , Findlay, J. E., Elliott, C. , Currie, S. and Baillie, G. S. (2014) Targeted disruption of the heat shock protein 20–phosphodiesterase 4D (PDE4D) interaction protects against pathological cardiac remodelling in a mouse model of hypertrophy. FEBS Open Bio, 4, pp. 923-927. (doi: 10.1016/j.fob.2014.10.011) (PMID:25426411) (PMCID:PMC4239479)
Mohan, H. et al. (2014) Transcript profiling of different types of multiple sclerosis lesions yields FGF1 as a promoter of remyelination. Acta Neuropathologica Communications, 2, 178. (doi: 10.1186/s40478-014-0168-9) (PMID:25589163) (PMCID:PMC4359505)
2012
Elliott, C. et al. (2012) Functional identification of pathogenic autoantibody responses in patients with multiple sclerosis. Brain, 135(6), pp. 1819-1833. (doi: 10.1093/brain/aws105)
2011
Brennan, K.M. et al. (2011) Lipid arrays identify myelin-derived lipids and lipid complexes as prominent targets for oligoclonal band antibodies in multiple sclerosis. Journal of Neuroimmunology, 238(1-2), pp. 87-95. (doi: 10.1016/j.jneuroim.2011.08.002)
Articles
Lipina, T. et al. (2024) PDE4B missense variant increases susceptibility to post-traumatic stress disorder-relevant phenotypes in mice. Journal of Neuroscience, (Accepted for Publication)
Glennon, E. B. et al. (2020) Bridging integrator 1 protein loss in Alzheimer’s disease promotes synaptic tau accumulation and disrupts tau release. Brain Communications, 2(1), fcaa011. (doi: 10.1093/braincomms/fcaa011) (PMID:32500121) (PMCID:PMC7272218)
Elliott, C. et al. (2018) A role for APP in Wnt signalling links synapse loss with β-amyloid production. Translational Psychiatry, 8, 179. (doi: 10.1038/s41398-018-0231-6) (PMID:30232325) (PMCID:PMC6145937)
Engelhardt, B., Holze, J., Elliott, C. , Baillie, G.S. , Kschischo, M. and Fröhlich, H. (2018) Modelling and mathematical analysis of the M2 receptor-dependent joint signalling and secondary messenger network in CHO cells. Mathematical Medicine and Biology, 35(3), pp. 279-297. (doi: 10.1093/imammb/dqx003) (PMID:28505258)
Sellers, K. J. et al. (2018) Amyloid β synaptotoxicity is Wnt-PCP dependent and blocked by fasudil. Alzheimer's and Dementia, 14(3), pp. 306-317. (doi: 10.1016/j.jalz.2017.09.008) (PMID:29055813) (PMCID:PMC5869054)
Yalla, K. et al. (2018) FBXW7 regulates DISC1 stability via the ubiquitin-proteosome system. Molecular Psychiatry, 23(5), pp. 1278-1286. (doi: 10.1038/mp.2017.138) (PMID:28727686) (PMCID:PMC5984089)
Ashton, N.J., Hye, A., Leckey, C.A., Jones, A.R., Elliott, C. , Wetherell, J.L., Lenze, E.J., Killick, R. and Marchant, N.L. (2017) Plasma REST: a novel candidate biomarker of Alzheimer’s disease is modified by psychological intervention in an at-risk population. Translational Psychiatry, 7, e1148. (doi: 10.1038/tp.2017.113) (PMID:28585932) (PMCID:PMC5537638)
Allan, D., Fairlie-Clarke, K. J., Elliott, C. , Schuh, C., Barnett, S. C. , Lassmann, H., Linnington, C. and Jiang, H.-R. (2016) Role of IL-33 and ST2 signalling pathway in multiple sclerosis: expression by oligodendrocytes and inhibition of myelination in central nervous system. Acta Neuropathologica Communications, 4(1), 75. (doi: 10.1186/s40478-016-0344-1) (PMID:27455844) (PMCID:PMC4960877)
Roscoe, R. B., Elliott, C. , Zarros, A. and Baillie, G. S. (2016) Non-genetic therapeutic approaches to Canavan disease. Journal of the Neurological Sciences, 366, pp. 116-124. (doi: 10.1016/j.jns.2016.05.012) (PMID:27288788)
Al Nimer, F. et al. (2016) Lipocalin-2 is increased in progressive multiple sclerosis and inhibits remyelination. Neurology: Neuroimmunology and Neuroinflammation, 3(1), e191. (doi: 10.1212/NXI.0000000000000191) (PMID:26770997) (PMCID:PMC4708925)
Dachtler, J., Elliott, C. , Rodgers, R. J., Baillie, G. S. and Clapcote, S. J. (2016) Missense mutation in DISC1 C-terminal coiled-coil has GSK3β signaling and sex-dependent behavioral effects in mice. Scientific Reports, 6, 18748. (doi: 10.1038/srep18748) (PMID:26728762) (PMCID:PMC4700527)
Tankou, S. et al. (2016) SUMOylation of DISC1: a potential role in neural progenitor proliferation in the developing cortex. Molecular Neuropsychiatry, 2(1), pp. 20-27. (doi: 10.1159/000444257) (PMID:27525255) (PMCID:PMC4979612)
Lindner, M. et al. (2015) Fibroblast growth factor signalling in multiple sclerosis: inhibition of myelination and induction of pro-inflammatory environment by FGF9. Brain, 138(7), pp. 1875-1893. (doi: 10.1093/brain/awv102) (PMID:25907862) (PMCID:PMC7185739)
Byrne, A. M., Elliott, C. , Hoffmann, R. and Baillie, G. S. (2015) The activity of cAMP-Phosphodiesterase 4D7 (PDE4D7) is regulated by protein kinase A-dependent phosphorylation within its unique N-terminus. FEBS Letters, 589(6), pp. 750-755. (doi: 10.1016/j.febslet.2015.02.004) (PMID:25680530) (PMCID:PMC4346272)
McGirr, A. et al. (2015) Specific inhibition of phosphodiesterase-4B results in anxiolysis and facilitates memory acquisition. Neuropsychopharmacology, 41(4), pp. 1080-1092. (doi: 10.1038/npp.2015.240)
Martin, T. P. , Hortigon-Vinagre, M. P. , Findlay, J. E., Elliott, C. , Currie, S. and Baillie, G. S. (2014) Targeted disruption of the heat shock protein 20–phosphodiesterase 4D (PDE4D) interaction protects against pathological cardiac remodelling in a mouse model of hypertrophy. FEBS Open Bio, 4, pp. 923-927. (doi: 10.1016/j.fob.2014.10.011) (PMID:25426411) (PMCID:PMC4239479)
Mohan, H. et al. (2014) Transcript profiling of different types of multiple sclerosis lesions yields FGF1 as a promoter of remyelination. Acta Neuropathologica Communications, 2, 178. (doi: 10.1186/s40478-014-0168-9) (PMID:25589163) (PMCID:PMC4359505)
Elliott, C. et al. (2012) Functional identification of pathogenic autoantibody responses in patients with multiple sclerosis. Brain, 135(6), pp. 1819-1833. (doi: 10.1093/brain/aws105)
Brennan, K.M. et al. (2011) Lipid arrays identify myelin-derived lipids and lipid complexes as prominent targets for oligoclonal band antibodies in multiple sclerosis. Journal of Neuroimmunology, 238(1-2), pp. 87-95. (doi: 10.1016/j.jneuroim.2011.08.002)