Healthcare Data

Our researchers lead national and international efforts to improve patient outcomes using healthcare data across cardiovascular, cerebrovascular, kidney disease, diabetes, geriatric care and COVID-19. 

Staff

Publications

2024

Smith, C., Wallis, S., Katsas, G., Dincarslan, O., Dawson, J., Cameron, A. (2024) Impact of European Stroke Organisation secondary prevention guideline for ischaemic stroke / transient ischaemic attack. Journal of Stroke and Cerebrovascular Diseases, 33, (doi: 10.1016/j.jstrokecerebrovasdis.2024.108034)

De Biase, N., Del Punta, L., L'Hoyes, W., Pellicori, P., Cleland, J. G.F., Masini, G., Gargani, L., Moura-Ferreira, S., Hoedemakers, S., Di Fiore, V., Herbots, L., Stassen, J., Mengozzi, A., Armenia, S., Taddei, S., Masi, S., Verwerft, J., Pugliese, N. R. (2024) Associations of iron deficiency with cardiac function, congestion, exercise capacity and prognosis in heart failure. European Journal of Heart Failure,

Rochmawati, I. D., Deo, S., Lees, J. S., Mark, P. B., Sattar, N., Celis-Morales, C., Pell, J. P., Welsh, P., Ho, F. K. (2024) Adding traditional and emerging biomarkers for risk assessment in secondary prevention: a prospective cohort study of 20,656 patients with cardiovascular disease. European Journal of Preventive Cardiology, (doi: 10.1093/eurjpc/zwae352)

Xiong, X., Lui, D. T.W., Ju, C., Zhou, Z., Xu, C., Welsh, P., Sattar, N., Celis-Morales, C., Pell, J. P., Wong, I. C.K., Wong, C. K.H., Ho, F. (2024) Associations of serum lipid traits with fracture and osteoporosis: a prospective cohort study from the UK Biobank. Journal of Cachexia, Sarcopenia and Muscle, (doi: 10.1002/jcsm.13611)

Dieden, A., Girerd, N., Ottosson, F., Molvin, J., Pareek, M., Melander, O., Bachus, E., Råstam, L., Lindblad, U., Daka, B., Leósdóttir, M., Nilsson, P. M., Olsen, M. H., Clark, A. L., Cleland, J. G.F., Delles, C., González, A., Lamiral, Z., Duarte, K., Rossignol, P., Zannad, F., Gudmundsson, P., Jujić, A., Magnusson, M. (2024) Proteomic biomarkers and pathway analysis for progression to heart failure in three epidemiological representative cohorts. European Journal of Heart Failure, (doi: 10.1002/ejhf.3502)

Foley, P.W., Kalra, P.R., Cleland, J.G.F., Petrie, M.C., Kalra, P.A., Squire, I., Campbell, P., Chapman, C., Donnelly, P., Graham, F., Hannah, A., Lang, N.N., Matthews, I., Leslie, S.J., Pellicori, P., Piper, S., Ray, R., Savage, H.O., Spencer, C., Walsh, J., Wong, Y., Ford, I. (2024) Effect of correcting iron deficiency on the risk of serious infection in heart failure insights from the IRONMAN trial. European Journal of Heart Failure, (doi: 10.1002/ejhf.3504)

Lu, H., Claggett, B. L., Packer, M., Pfeffer, M. A., Swedberg, K., Rouleau, J., Zile, M. R., Lefkowitz, M., Desai, A. S., Jhund, P. S., McMurray, J. J.V., Solomon, S. D., Vaduganathan, M. (2024) Visit‐to‐visit changes in heart rate in heart failure: A pooled participant‐level analysis of the PARADIGM‐HF and PARAGON‐HF trials. European Journal of Heart Failure, (doi: 10.1002/ejhf.3487)

Walker, H., Sullivan, M. K., Jani, B. D., Mark, P. B., Gallacher, K. I. (2024) Exploration of patients’ and health care professionals’ perspectives of kidney failure risk and the use of the kidney failure risk equation in MULTIPle lOng-term condItions aNd frailTy (MULTIPOINT) study: a qualitative interview and focus group study protocol. BMJ Open, 14, (doi: 10.1136/bmjopen-2024-085843)

Walker, H., Day, S., Grant, C. H., Jones, C., Ker, R., Sullivan, M. K., Jani, B. D., Gallacher, K., Mark, P. B. (2024) Representation of multimorbidity and frailty in the development and validation of kidney failure prognostic prediction models: a systematic review. BMC Medicine, 22, (doi: 10.1186/s12916-024-03649-9)

MacRae, J., Ciminata, G., Geue, C., Lynch, E., Shenkin, S. D., Quinn, T. J., Burton, J. K. (2024) Mortality among long-term care residents: a retrospective cohort study. BMJ Supportive and Palliative Care, (doi: 10.1136/spcare-2024-005163)

Varga, C. R., Cleland, J. G.F., Abraham, W. T., Lip, G. Y.H., Leyva, F., Hatamizadeh, P. (2024) Implantable cardioverter defibrillator and resynchronization therapy in patients with overt chronic kidney disease. Journal of the American College of Cardiology, 84, pp. 1342-1362. (doi: 10.1016/j.jacc.2024.05.081)

Ho, F., Allan, M., Shao, H., Man, K. K.C., Jani, B. D., Lyall, D., Hastie, C., Fleming, M., Mackay, D., Cleland, J. G.F., Delles, C., Dundas, R., Lewsey, J., Ip, P., Wong, I., Welsh, P., Pearce, A., Wright, C. M., Minnis, H., Katikireddi, V., Pell, J. P. (2024) Maternal and pregnancy factors contributing to the association between area deprivation and infant mortality in England: a retrospective cohort study. Lancet Regional Health - Europe, (doi: 10.1016/j.lanepe.2024.101075)

Lee, M., Petrie, M. C., Cleland, J. G.F., Donnelly, P., Francis, M., Hannah, A., Japp, A. G., Labinjoh, C., Lang, N. N., Mainsty, C., Petrie, C. J., Piper, S. E., Williams, S. G., Ford, I., Kalra, P. R., IRONMAN Trial Investigators, (2024) Administration of ferric derisomaltose for iron deficiency and heart failure during hospital admission or at the clinic – insights from the IRONMAN trial. European Journal of Heart Failure, 26, pp. 2293-2295. (doi: 10.1002/ejhf.3394)

Liu, Q., Celis-Morales, C., Lees, J. S., Sattar, N., Ho, F., Pell, J. P., Mark, P. B., Welsh, P. (2024) Change in physical activity and its association with decline in kidney function: A UK Biobank-based cohort study. Journal of Cachexia, Sarcopenia and Muscle, 15, pp. 2046-2055. (doi: 10.1002/jcsm.13551)

Cleland, J. G.F. (2024) Home-time is good, but feeling well is better: patient-journey and quality-home-time as endpoints in heart failure trials and registries. Circulation: Heart Failure, 17, (doi: 10.1161/CIRCHEARTFAILURE.124.012263)

Abdin, A., Jhund, P. S. (2024) Implementation of guideline‐directed medical therapy for heart failure: Progress achieved, work ahead! European Journal of Heart Failure, 26, pp. 2258-2260. (doi: 10.1002/ejhf.3438)

Pellicori, P., Cuthbert, J. J., Clark, A. L., Cleland, J. G.F. (2024) Managing water and salt balance in heart failure: Is there anything else to consider other than diet and diuretics? European Journal of Heart Failure, 26, pp. 2140-2142. (doi: 10.1002/ejhf.3374)

Keene, D. et al. (2024) Predictors of the efficacy of His bundle pacing in patients with a prolonged PR interval: A stratified analysis of the HOPE‐HF randomized controlled trial. European Journal of Heart Failure, 26, pp. 2261-2268. (doi: 10.1002/ejhf.3367)

Yu, Y.-L. et al. (2024) Urinary proteomic signature of mineralocorticoid receptor antagonism by spironolactone: evidence from the HOMAGE trial. Heart, 110, pp. 1180-1187. (doi: 10.1136/heartjnl-2023-323796)

Cheng, L., Hammersley, D., Ragavan, A., Javed, S., Mukhopadhyay, S., Gregson, J., Han, J., Khalique, Z., Lota, A., Pantazis, A., Baksi, A. J., Carr‐White, G., de Marvao, A., Ware, J., Tayal, U., Pennell, D. J., Cleland, J. G.F., Prasad, S. K., Halliday, B. P. (2024) Long‐term follow‐up of the TRED ‐ HF trial: Implications for therapy in patients with dilated cardiomyopathy and heart failure remission. European Journal of Heart Failure, (doi: 10.1002/ejhf.3475)

Wang, X., Pabon, M. A., Cikes, M., Jering, K., Mullens, W., Kober, L., Jhund, P. S., Kovacs, A., Merkely, B., Zhou, Y., McMurray, J. J.V., Shah, A. M., Hegde, S. M., Claggett, B., Pfeffer, M. A., Solomon, S. D. (2024) Sex differences in cardiac structure and function following acute myocardial infarction: Insights from the PARADISE‐MI echocardiographic substudy. European Journal of Heart Failure, (doi: 10.1002/ejhf.3472)

Jhund, P. S., Talebi, A., Henderson, A. D., Claggett, B. L., Vaduganathan, M., Desai, A. S., Lam, C. S.P., Pitt, B., Senni, M., Shah, S. J., Voors, A. A., Zannad, F., Solomon, S. D., McMurray, J. J.V. (2024) Mineralocorticoid receptor antagonists in heart failure: an individual patient level meta-analysis. Lancet, 404, pp. 1119-1131. (doi: 10.1016/S0140-6736(24)01733-1)

Anderson, J. J., Deo, S. V., Welsh, P., Mackay, D. F., Ho, F. K., Ferguson, L. D., Celis-Morales, C., Gill, J.R., Pell, J. P., Sattar, N. (2024) In which common chronic conditions can (or cannot) obesity and lifestyle factors explain higher concentrations of C-reactive protein? Diabetes, Obesity and Metabolism, (doi: 10.1111/dom.15949)

Pabon, M. A., Vaduganathan, M., Claggett, B. L., Chatur, S., Siqueira, S., Marti‐Castellote, P., de Boer, R. A., Hernandez, A. F., Inzucchi, S. E., Kosiborod, M. N., Lam, C. S.P., Martinez, F., Shah, S. J., Desai, A. S., Jhund, P. S., McMurray, J. J.V., Solomon, S. D., Vardeny, O. (2024) In‐hospital course of patients with heart failure with improved ejection fraction in the DELIVER trial. European Journal of Heart Failure, (doi: 10.1002/ejhf.3410)

Valentova, M., Vatic, M., Garfias-Veitl, T., Sandek, A., Bekfani, T., Jankowska, E. A., Cleland, J. G.F., Clark, A. L., Lainscak, M., Ahmed, A., Jauert, N., Hasenfuss, G., Anker, S. D., Doehner, W., von Haehling, S. (2024) Diabetes mellitus is associated with low exercise capacity and impaired peripheral vasodilation in patients with heart failure – a propensity score-matched stud. Diabetes Research and Clinical Practice,

Drummond, M., Cartin, K., Shenkin, S.D., Burton, J.K. (2024) Facilitating equitable research access for people living in care homes. Age and Ageing,

Greene, S. J. et al. (2024) Cardiovascular and renal treatment in heart failure patients with hyperkalemia or high risk of hyperkalemia: rationale and design of the CARE-HK in HF registry. Journal of Cardiac Failure, (doi: 10.1016/j.cardfail.2024.08.048)

Zhou, M., Mary, S., Delles, C., Padmanabhan, S., Graham, D., McBride, M. W., Dominiczak, A. (2024) Insights into uromodulin and blood pressure. Current Hypertension Reports, (doi: 10.1007/s11906-024-01317-0)

Cuthbert, J. J., Cleland, J. G. F., Pellicori, P., Clark, A. L. (2024) Natriuresis guided diuresis in patients admitted to hospital with heart failure – barking up the wrong tree? Journal of Cardiac Failure,

Lu, H., Claggett, B. L., Packer, M., Pfeffer, M. A., Lam, C. S.P., Zile, M. R., Desai, A. S., Jhund, P., Lefkowitz, M., McMurray, J. J.V., Solomon, S. D., Vaduganathan, M. (2024) Sacubitril/valsartan reduces incident anaemia and iron therapy utilization in heart failure: The PARAGON‐HF trial. European Journal of Heart Failure, (doi: 10.1002/ejhf.3414)

Morrow, A. et al. (2024) Zibotentan in microvascular angina: a randomized, placebo-controlled, crossover trial. Circulation, (doi: 10.1161/CIRCULATIONAHA.124.069901)

Al-Abdullah, L., Ahern, A., Welsh, P., Logue, J. (2024) A predictive model for medium-term weight loss response in people with type 2 diabetes engaging in behavioural weight management interventions. Diabetes, Obesity and Metabolism, 26, pp. 3653-3662. (doi: 10.1111/dom.15706)

Butt, J., Jhund, P. S., Docherty, K. F., Claggett, B. L., Vaduganathan, M., Bachus, E., Hernandez, A. F., Lam, C. S.P., Inzucchi, S. E., Martinez, F. A., de Boer, R. A., Kosiborod, M. N., Desai, A. S., Køber, L., Ponikowski, P., Sabatine, M. S., Solomon, S. D., McMurray, J. J.V. (2024) Dapagliflozin and timing of prior heart failure hospitalization a patient-level meta-analysis of DAPA-HF and DELIVER. JACC: Heart Failure, 12, pp. 1586-1599. (doi: 10.1016/j.jchf.2024.01.018)

Seferović, P. M., Paulus, W. J., Rosano, G., Polovina, M., Petrie, M. C., Jhund, P. S., Tschöpe, C., Sattar, N., Piepoli, M., Papp, Z., Standl, E., Mamas, M. A., Valensi, P., Linhart, A., Lalić, N., Ceriello, A., Döhner, W., Ristić, A., Milinković, I., Seferović, J., Cosentino, F., Metra, M., Coats, A. J.S. (2024) Diabetic myocardial disorder. A clinical consensus statement of the Heart Failure Association of the ESC and the ESC Working Group on Myocardial & Pericardial Diseases. European Journal of Heart Failure, 26, pp. 1893-1903. (doi: 10.1002/ejhf.3347)

Abdin, A., Kondo, T., Böhm, M., Jhund, P. S., Claggett, B. L., Vaduganathan, M., Hernandez, A. F., Lam, C. S.P., Inzucchi, S. E., Martinez, F. A., de Boer, R. A., Desai, A. S., Køber, L., Sabatine, M. S., Petersson, M., Bachus, E., Solomon, S. D., McMurray, J. (2024) Effects of dapagliflozin according to QRS duration across the spectrum of left ventricular ejection fraction: an analysis of DAPA-HF and DELIVER. European Journal of Heart Failure, 26, pp. 1952-1963. (doi: 10.1002/ejhf.3350)

Butt, J. H., McMurray, J. J.V., Claggett, B. L., Jhund, P. S., Neuen, B. L., McCausland, F., Desai, A., Lam, C. S.P., Pitt, B., Pfeffer, M. A., Packer, M., Beldhuis, I., Voors, A. A., Zannad, F., Heerspink, H. J.L., Solomon, S. D., Vaduganathan, M. (2024) Therapeutic effects of heart failure medical therapies on standardized kidney outcomes: Comprehensive individual participant-level analysis of 6 randomized clinical trials. Circulation, (doi: 10.1161/circulationaha.124.071110)

Matsumoto, S., Henderson, A. D., Shen, L., Kondo, T., Yang, M., Campbell, R. T., Anand, I. S., de Boer, R. A., Desai, A. S., Lam, C. S.P., Maggioni, A. P., Martinez, F. A., Packer, M., Redfield, M. M., Rouleau, J. L., Van Veldhuisen, D. J., Vaduganathan, M., Zannad, F., Zile, M. R., Jhund, P. S., Solomon, S. D., McMurray, J. J.V. (2024) Beta‐blocker use and outcomes in patients with heart failure and mildly reduced and preserved ejection fraction. European Journal of Heart Failure, (doi: 10.1002/ejhf.3383)

Ponikowski, P. et al. (2024) Hospitalization of symptomatic patients with heart failure and moderate to severe functional mitral regurgitation treated with MitraClip: insights from RESHAPE-HF2. JACC: Heart Failure, (doi: 10.1016/j.jacc.2024.08.027)

Giannitsis, E., Frey, N., Jhund, P. S. (2024) Improving the rate of heart failure with improved ejection fraction. European Journal of Heart Failure, (doi: 10.1002/ejhf.3427)

Yang, M., Kondo, T., Anand, I. S., de Boer, R. A., Campbell, R. T., Køber, L., Lam, C. S.P., Maggioni, A. P., Martinez, F. A., O'Meara, E., Packer, M., Sabatine, M. S., Kerr Saraiva, J. F., Shah, S. J., Zannad, F., Zile, M. R., Jhund, P. S., Solomon, S. D., McMurray, J. J.V. (2024) Clinical characteristics and outcomes of patients aged 80 years and over with heart failure: Need for better treatment. European Journal of Heart Failure, (doi: 10.1002/ejhf.3417)

Liu, Q., Celis-Morales, C., Sattar, N., Welsh, P. (2024) Association of glycaemic control with intraocular pressure in a large general population: Results from the UK Biobank. Diabetes, Obesity and Metabolism, (doi: 10.1111/dom.15865)

Liu, Q., Celis-Morales, C., Sattar, N., Welsh, P. (2024) Association of glycemic control with intraocular pressure in a large general population: results from the UK Biobank. Diabetes, Obesity and Metabolism, (doi: 10.1111/dom.15865)

Graham, F. J., Guha, K., Cleland, J. G., Kalra, P. R. (2024) Treating iron deficiency in patients with heart failure: what, why, when, how, where and who. Heart, (doi: 10.1136/heartjnl-2022-322030)

Cleland, J., Pellicori, P., Graham, F. J., Lane, R., Petrie, M. C., Ahmed, F., Squire, I. B., Ludman, A., Japp, A., Al-Mohammad, A., Clark, A. L., Szwejkowski, B., Critoph, C., Chong, V., Schiff, R., Nageh, T., Glover, J., McMurray, J. J.V., Thomson, E. A., Robertson, M., Ford, I., Kalra, P. A., Kalra, P. R. (2024) The IRONMAN trial of intravenous iron for heart failure. Adjudication of hospitalizations and deaths. Journal of the American College of Cardiology,

Cameron, A., Arnold, M., Katsas, G., Yang, J., Quinn, T. J., Abdul-Rahim, A. H., Campbell, R., Docherty, K., De Marchis, G. M., Arnold, M., Kahles, T., Nedeltchev, K., Cereda, C., Kaegi, G., Bustamante, A., Montaner, J., Ntaios, G., Foerch, C., Spanaus, K., Von Eckardstein, A., Dawson, J., Katan, M. (2024) Natriuretic peptides to classify risk of atrial fibrillation detection after stroke: analysis of the BIOSIGNAL and PRECISE cohort studies. Neurology, 103, (doi: 10.1212/WNL.0000000000209625)

Elyan, B. M.P., Sullivan, M. K., Hedley, J., De La Mata, N., Webster, A. C., Venugopal, B., Jones, R. J., Lang, N. N., Mark, P. B., Lees, J. S. (2024) The impact of VEGF signalling pathway inhibitors and/or immune checkpoint inhibitors on kidney function over time: a single centre retrospective analysis. BJC Reports, 2, (doi: 10.1038/s44276-024-00081-7)

Cao, T. H., Tay, W. T., Jones, D. J.L., Cleland, J. G.F., Tromp, J., Emmens, J. E., Teng, T.‐H. K., Chandramouli, C., Slingsby, O. C., Anker, S. D., Dickstein, K., Filippatos, G., Lang, C. C., Metra, M., Ponikowski, P., Samani, N. J., Van Veldhuisen, D. J., Zannad, F., Anand, I. S., Lam, C. S.P., Voors, A. A., Ng, L. L. (2024) Heart failure with improved versus persistently reduced left ventricular ejection fraction: A comparison of the BIOSTAT‐CHF (European) study with the ASIAN‐HF registry. European Journal of Heart Failure, (doi: 10.1002/ejhf.3378)

Kazmi, S., Kambhampati, C., Rigby, A. S., Cleland, J. G.F., Kazmi, K. S., Cuthbert, J., Pellicori, P., Clark, A. L. (2024) Disease progression in chronic heart failure is linear: insights from multistate modelling. European Journal of Heart Failure, (doi: 10.1002/ejhf.3400)

Gustafsson, F., Petrie, M. C., Komtebedde, J., Swarup, V., Winkler, S., Hasenfuß, G., Borlaug, B. A., Mohan, R. C., Flaherty, J. D., Sverdlov, A. L., Fail, P. S., Chung, E. S., Lurz, P., Lilly, S., Kaye, D. M., Cleland, J. G.F., Cikes, M., Leon, M. B., Cutlip, D. E., van Veldhuisen, D. J., Solomon, S. D., Shah, S. J. (2024) 2-year outcomes of an atrial shunt device in HFpEF/HFmrEF: results from REDUCE LAP-HF II. JACC: Heart Failure, 12, pp. 1425-1438. (doi: 10.1016/j.jchf.2024.04.011)

Sudesh, S., Abraham, W. T., Cleland, J. G.F., Curtis, A. B., Friedman, D. J., Gold, M. R., Kutyifa, V., Linde, C., Tang, A. S., Olivas-Martinez, A., Inoue, L. Y.T., Sanders, G. D., Al-Khatib, S. M. (2024) Cardiac resynchronization therapy in ischemic versus non-ischemic cardiomyopathy: patient-level meta-analysis of seven randomized clinical trials. JACC: Heart Failure,

Carberry, J., Petrie, M. C., Lee, M. M.Y., Brooksbank, K., Campbell, R. T., Good, R., Jhund, P. S., Kellman, P., Lang, N. N., Mangion, K., Mark, P. B., McConnachie, A., McMurray, J. J.V., Meyer, B., Orchard, V., Shaukat, A., Watkins, S., Welsh, P., Sattar, N., Berry, C., Docherty, K. F. (2024) Empagliflozin to prevent progressive adverse remodelling after myocardial infarction (EMPRESS-MI): rationale and design. ESC Heart Failure, 11, pp. 2001-2012. (doi: 10.1002/ehf2.14830)

Grobbee, D. E., Filippatos, G., Desai, N. R., Coats, A. J.S., Pinto, F., Rosano, G. M.C., Cleland, J., Kammerer, J., Ramirez de Arellano, A. (2024) Epidemiology and risk factors for hyperkalaemia in heart failure. ESC Heart Failure, 11, pp. 1821-1840. (doi: 10.1002/ehf2.14661)

Yang, M., Kondo, T., Jhund, P. S., Alcocer‐Gamba, M. A., Borleffs, C. J. W., Chiang, C.‐E., Comin‐Colet, J., Desai, A. S., Dobreanu, D., Drożdż, J., Han, Y., Janssens, S. P., Katova, T., Kosiborod, M. N., Lam, C. S.P., Merkely, B., Pham, V. N., Thierer, J., Vaduganathan, M., Verma, S., Solomon, S. D., McMurray, J. J.V. (2024) Geographical variation in patient characteristics and outcomes in heart failure with mildly reduced and preserved ejection fraction. European Journal of Heart Failure, 26, pp. 1788-1803. (doi: 10.1002/ejhf.3352)

Docherty, K. F., McMurray, J. J.V., Kalra, P., Cleland, J. G.F., Lang, N. N., Petrie, M. C., Robertson, M., Ford, I. (2024) Intravenous iron and SGLT2 inhibitors in iron-deficient patients with heart failure and reduced ejection fraction. ESC Heart Failure, 11, pp. 1875-1879. (doi: 10.1002/ehf2.14742)

Kondo, T., Campbell, R., Jhund, P. S., Anand, I. S., Carson, P. E., Lam, C. S.P., Shah, S. J., Vaduganathan, M., Zannad, F., Zile, M. R., Solomon, S. D., McMurray, J. J.V. (2024) Low natriuretic peptide levels and outcomes in patients with heart failure and preserved ejection fraction. JACC: Heart Failure, 12, pp. 1442-1455. (doi: 10.1016/j.jchf.2024.04.027)

Minnis, M., Burton, J. K., Kelbling, E., Gallacher, K. I., Quinn, T. J. (2024) Not daily, sometimes not ever – mixed methods exploration of the contemporary relevance of tasks contained in extended activities of daily living scales. Age and Ageing, 53, (doi: 10.1093/ageing/afae185)

Zahir Anjum, D., Strange, J. E., Fosbøl, E., Garred, C. H., Elmegaard, M., Andersson, C., Jhund, P. S., McMurray, J. J.V., Petrie, M. C., Kober, L., Schou, M. (2024) Use of medical therapy and risk of clinical events according to frailty in heart failure patients – A real‐life cohort study. European Journal of Heart Failure, 26, pp. 1717-1726. (doi: 10.1002/ejhf.3249)

McCallum, L., Lip, S., McConnachie, A., Brooksbank, K., MacIntyre, I., Doney, A., Llano, A., Aman, A., Caparrotta, T. M., Ingram, G., Mackenzie, I. S., Dominiczak, A. F., MacDonald, T. M., Webb, D. J., Padmanabhan, S. (2024) UMOD genotype-dependent effects of Torasemide on ambulatory blood pressure: a multicentre genotype-blinded trial. Hypertension, (doi: 10.1161/HYPERTENSIONAHA.124.23122)

Bahar, J., Rahman, A., Wong, G. W.Y., Sankaranarayanan, R., Ahmed, F. Z., Taylor, R., Fuat, A., Squire, I., Cleland, J., Lip, G. Y.H., Gamble, J. H.P., Masudi, S., Joseph, P. J. S., Wong, K. (2024) Outpatient treatment of decompensated heart failure: a systematic review and study level meta-analysis. ESC Heart Failure, (doi: 10.1002/ehf2.14841)

Rubiś, P. P., Dziewięcka, E., González, A., Cleland, J. G.F. (2024) High variability in assays of blood markers of collagen turnover in cardiovascular disease: Implications for research and clinical practice. European Journal of Heart Failure, (doi: 10.1002/ejhf.3375)

Aguiar-Neves, I., Diaz, S. O., Ferreira, J. P., Girerd, N., Pellicori, P., Mariottoni, B., Cosmi, F., Hazebroek, M., Verdonschot, J. A.J., Cuthbert, J., Petutschnigg, J., Heymans, S., Staessen, J. A., Pieske, B., Edelmann, F., Clark, A. L., Rossignol, P., Fontes-Carvalho, R., Cleland, J. G., Zannad, F. (2024) Health status and effects of spironolactone in people at high risk of heart failure: the Heart OMics in AGEing (HOMAGE) randomised trial. Clinical Cardiology,

Churuangsuk, C., Catchpole, A., Talwar, D., Welsh, P., Sattar, N., Combet Aspray, E., Lean, M. E.J. (2024) Low thiamine status in adults following low-carbohydrate / ketogenic diets: a cross-sectional comparative study of micronutrient intake and status. European Journal of Nutrition, (doi: 10.1007/s00394-024-03459-y)

Ostrominski, J. W., Claggett, B. L., Miao, Z. M., Mc Causland, F. R., Anand, I. S., Desai, A. S., Jhund, P. S., Lam, C. S.P., Pfeffer, M. A., Pitt, B., Zannad, F., Zile, M. R., Bomfim Wirtz, A., Lay-Flurrie, J., Viswanathan, P., McMurray, J. J.V., Solomon, S. D., Vaduganathan, M. (2024) Cardiovascular-kidney-metabolic overlap in heart failure with mildly reduced or preserved ejection fraction a trial-level analysis. Journal of the American College of Cardiology, 84, pp. 223-228. (doi: 10.1016/j.jacc.2024.05.005)

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2023

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Welsh, P., Kimenai, D. M., Shah, A. S.V., Gadd, D. A., Marioni, R. E., Woodward, M., Sudlow, C. L.M., Campbell, A., Cleland, J. G.F., Pellicori, P., Hayward, C., Mills, N. L., Sattar, N. (2023) Multiple cardiac biomarkers to improve prediction of cardiovascular events: findings from the Generation Scotland Scottish Family Health Study. Clinical Chemistry, 70, pp. 403-413. (doi: 10.1093/clinchem/hvad205)

Vardeny, O., Fang, J. C., Desai, A. S., Jhund, P. S., Claggett, B., Vaduganathan, M., de Boer, R. A., Hernandez, A. F., Lam, C. S. P., Inzucchi, S. E., Martinez, F. A., Kosiborod, M. N., DeMets, D., O’Meara, E., Zieroth, S., Comin-Colet, J., Drozdz, J., Chiang, C.-E., Kitakaze, M., Petersson, M., Lindholm, D., Langkilde, A. M., McMurray, J. J.V., Solomon, S. D. (2023) Author Correction: Dapagliflozin in heart failure with improved ejection fraction: a prespecified analysis of the DELIVER trial. Nature Medicine, 29, pp. 3269-3269. (doi: 10.1038/s41591-023-02302-x)

Matsumoto, S., Kondo, T., Yang, M., Campbell, R. T., Docherty, K. F., de Boer, R. A., Desai, A. S., Lam, C. S.P., Packer, M., Pitt, B., Rouleau, J. L., Vaduganathan, M., Zannad, F., Zile, M. R., Solomon, S. D., Jhund, P. S., McMurray, J. J.V. (2023) Calcium channel blocker use and outcomes in patients with heart failure and mildly reduced and preserved ejection fraction. European Journal of Heart Failure, 25, pp. 2202-2214. (doi: 10.1002/ejhf.3044)

Kondo, T., Butt, J. H., Curtain, J. P., Jhund, P. S., Docherty, K. F., Claggett, B. L., Vaduganathan, M., Bachus, E., Hernandez, A. F., Lam, C. S.P., Inzucchi, S. E., Martinez, F. A., de Boer, R. A., Kosiborod, M. N., Desai, A. S., Køber, L., Ponikowski, P., Sabatine, M. S., Solomon, S. D., McMurray, J. J.V. (2023) Efficacy of dapagliflozin according to heart rate: A patient-level pooled analysis of DAPA-HF and DELIVER. Circulation: Heart Failure, 16, (doi: 10.1161/CIRCHEARTFAILURE.123.010898)

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Zahir Anjum, D., Strange, J. E., Fosbøl, E., Garred, C. H., Malik, M. E., Andersson, C., Jhund, P. S., McMurray, J. J.V., Petrie, M. C., Kober, L., Schou, M. (2023) Initiation of medical therapy for heart failure patients according to kidney function: a Danish nationwide study. Clinical Epidemiology, 15, pp. 855-866. (doi: 10.2147/clep.s412787)

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Chatur, S., Vaduganathan, M., Claggett, B. L., Cunningham, J. W., Docherty, K. F., Desai, A. S., Jhund, P. S., De Boer, R. A., Hernandez, A. F., Inzucchi, S. E., Kosiborod, M. N., Lam, C. S. P., Martinez, F. A., Shah, S. J., Petersson, M., Langkilde, A.-M., McMurray, J. J. V., Solomon, S. D. (2023) Outpatient worsening among patients with mildly reduced and preserved ejection fraction heart failure in the DELIVER trial. Circulation, 148, pp. 1735-1745. (doi: 10.1161/circulationaha.123.066506)

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Hanratty, B., Wolters, A.T., Towers, A.M., Spilsbury, K., Meyer, J., Killett, A., Jones, L., Gordon, A., Burton, J.K., Akdur, G., Irvine, L., Warmoth, K., Liddle, J., Goodman, C. (2023) Data collection in care homes for older adults: A national survey in England. Journal of Long-Term Care, 2023, pp. 288-296. (doi: 10.31389/jltc.199)

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Ostrominski, J. W., Claggett, B. L., Packer, M., Pfeffer, M. A., Lam, C. S.P., Zile, M. R., Desai, A. S., Jhund, P. S., Lefkowitz, M., McMurray, J. J.V., Solomon, S. D., Vaduganathan, M. (2023) Duration of heart failure with preserved ejection fraction and outcomes with sacubitril/valsartan: insights from the PARAGON-HF trial. Journal of Cardiac Failure, 29, pp. 1494-1503. (doi: 10.1016/j.cardfail.2023.05.003)

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Butt, J. H., Lu, H., Kondo, T., Bachus, E., de Boer, R. A., Inzucchi, S. E., Jhund, P. S., Kosiborod, M. N., Lam, C. S.P., Martinez, F. A., Vaduganathan, M., Solomon, S. D., McMurray, J. J.V. (2023) Heart failure, chronic obstructive pulmonary disease and efficacy and safety of dapagliflozin in heart failure with mildly reduced or preserved ejection fraction: insights from DELIVER. European Journal of Heart Failure, 25, pp. 2078-2090. (doi: 10.1002/ejhf.3000)

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Burger, P. M. et al. (2023) Personalized lifetime prediction of survival and treatment benefit in patients with heart failure with reduced ejection fraction: the LIFE-HF model. European Journal of Heart Failure, 25, pp. 1962-1975. (doi: 10.1002/ejhf.3028)

Sattar, N., Taheri, S., Astling, D. P., Chadwick, J., Hinterberg, M. A., Holmes, M. V., Troth, E. V., Welsh, P., Zaghloul, H., Chagoury, O., Lean, M., Taylor, R., Williams, S. (2023) Prediction of cardiometabolic health through changes in plasma proteins with intentional weight loss in the DiRECT and DIADEM-I randomised clinical trials of type 2 diabetes remission. Diabetes Care, 46, pp. 1949-1957. (doi: 10.2337/dc23-0602)

Bradley, C. P., Orchard, V., McKinley, G., Heggie, R., Wu, O., Good, R., Watkins, S., Lindsay, M., Eteiba, H., McGowan, J., McGeoch, R., Corcoran, D., Kellman, P., McConnachie, A., Berry, C. (2023) The coronary microvascular angina cardiovascular magnetic resonance imaging trial: rationale and design. American Heart Journal, 265, pp. 213-224. (doi: 10.1016/j.ahj.2023.08.067)

Kondo, T., Gasparyan, S. B., Jhund, P. S., Bengtsson, O., Claggett, B. L., de Boer, R. A., Hernandez, A. F., Inzucchi, S. E., Kosiborod, M. N., Køber, L., Lam, C. S.P., Langkilde, A. M., Martinez, F. A., Petersson, M., Ponikowski, P., Sabatine, M. S., Shah, S. J., Sjostrand, M., Wilderang, U., Vaduganathan, M., Solomon, S. D., McMurray, J. J.V. (2023) Use of win statistics to analyze outcomes in the DAPA-HF and DELIVER trials. NEJM Evidence, 2, (doi: 10.1056/EVIDoa2300042)

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Graham, F. J., Pellicori, P., Masini, G., Cuthbert, J. J., Clark, A. L., Cleland, J. G.F. (2023) Influence of serum transferrin concentration on diagnostic criteria for iron deficiency in chronic heart failure. ESC Heart Failure, 10, pp. 2826-2836. (doi: 10.1002/ehf2.14438)

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Cuthbert, J. J., Cleland, J. G.F. (2023) Should we resurrect acetazolamide as a diuretic for congestion due to heart failure? Cardiovascular Research, 119, pp. e149-e151. (doi: 10.1093/cvr/cvad148)

Al Ozairi, E., Alsaeed, D., Al Rhoudan, D., Jalali, M., Mashankar, A., Taliping, D., Abdulla, A., Gill, J. M.R., Sattar, N., Welsh, P., Gray, S. R. (2023) The effect of home-based resistance exercise training in people with type 2 diabetes: a randomized controlled trial. Diabetes/Metabolism Research and Reviews, 39, (doi: 10.1002/dmrr.3677)

Wei, L., Phillippo, D. M., Shah, A., Cleland, J. G.F., Lewsey, J., McAllister, D. A. (2023) Transportability of two heart failure trials to a disease registry using individual patient data. Journal of Clinical Epidemiology, 162, pp. 160-168. (doi: 10.1016/j.jclinepi.2023.08.019)

Logan, G., Somers, C., Baker, G., Connell, H., Gray, S., Kelly, P., McIntosh, E., Welsh, P., Gray, C., Gill, J. M. (2023) Benefits, risks, barriers, and facilitators to cycling: a narrative review. Frontiers in Sports and Active Living, 5, (doi: 10.3389/fspor.2023.1168357)

Burton, J. K., Drummond, M., Gallacher, K. I., Quinn, T. J. (2023) Listening and learning: a qualitative study of Scottish care home staff experiences of managing COVID-19 between March 2020-August 2022. BMC Geriatrics, 23, (doi: 10.1186/s12877-023-04251-z)

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Kondo, T., Wang, X., Yang, M., Jhund, P. S., Claggett, B. L., Vaduganathan, M., Hernandez, A. F., Lam, C. S. P., Inzucchi, S. E., Martinez, F. A., de Boer, R. A., Kosiborod, M. N., Desai, A. S., Køber, L., Ponikowski, P., Sabatine, M. S., Langkilde, A. M., Petersson, M., Zaozerska, N., Bachus, E., Solomon, S. D., McMurray, J. J. V. (2023) Efficacy of dapagliflozin according to geographic location of patients with heart failure. Journal of the American College of Cardiology, 82, pp. 1014-1026. (doi: 10.1016/j.jacc.2023.05.056)

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2022

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2021

Mooney, L., Hawkins, N. M., Jhund, P. S., Redfield, M. M., Muthiah Vaduganathan, M., Desai, A. S., Rouleau, J. L., Minamisawa, M., Shah, A. M., Lefkowitz, M. P., Zile, M. R., Van Veldhuisen, D. J., Pfeffer, M. A., Anand, I. S., Maggioni, A. P., Senni, M., Claggett, B. L., Solomon, S. D., McMurray, J. J. V. (2021) Impact of chronic obstructive pulmonary disease in patients with heart failure with preserved ejection fraction: insights from PARAGON‐HF. Journal of the American Heart Association, 10, (doi: 10.1161/JAHA.121.021494)

Petermann-Rocha, F., Lyall, D. M., Gray, S. R., Gill, J. M.R., Sattar, N., Welsh, P., Quinn, T. J., Stewart, W., Pell, J. P., Ho, F. K., Celis-Morales, C. (2021) Dose-response association between device-measured physical activity and incident dementia: a prospective study from UK Biobank. BMC Medicine, 19, (doi: 10.1186/s12916-021-02172-5)

Macpherson, J. M., Gray, S. R., Ip, P., McCallum, M., Hanlon, P., Welsh, P., Chan, K. L., Mair, F. S., Celis-Morales, C., Minnis, H., Pell, J. P., Ho, F. K. (2021) Child maltreatment and incident mental disorders in middle and older ages: a retrospective UK Biobank cohort study. Lancet Regional Health - Europe, 11, (doi: 10.1016/j.lanepe.2021.100224)

Butt, J. H., Adamson, C., Docherty, K. F., de Boer, R. A., Petrie, M. C., Inzucchi, S. E., Kosiborod, M. N., Maria Langkilde, A., Lindholm, D., Martinez, F. A., Bengtsson, O., Schou, M., O’Meara, E., Ponikowski, P., Sabatine, M. S., Sjöstrand, M., Solomon, S. D., Jhund, P. S., McMurray, J. J.V., Køber, L. (2021) Efficacy and safety of dapagliflozin in heart failure with reduced ejection fraction according to N-terminal pro-B-type natriuretic peptide: insights from the DAPA-HF trial. Circulation: Heart Failure, 14, (doi: 10.1161/CIRCHEARTFAILURE.121.008837)

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Inzucchi, S. E., Docherty, K. F., Køber, L., Kosiborod, M. N., Martinez, F. A., Ponikowski, P., Sabatine, M. S., Solomon, S. D., Verma, S., Bělohlávek, J., Böhm, M., Chiang, C.-E., de Boer, R. A., Diez, M., Dukát, A., Ljungman, C. E.A., Bengtsson, O., Langkilde, A. M., Sjöstrand, M., Jhund, P. S., McMurray, J. J.V. (2021) Dapagliflozin and the incidence of type 2 diabetes in patients with heart failure and reduced ejection fraction: an exploratory analysis from DAPA-HF. Diabetes Care, 44, pp. 586-594. (doi: 10.2337/dc20-1675)

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Felker, G. M. et al. (2021) Effects of a novel nitroxyl donor in acute heart failure: the STAND-UP AHF Study. JACC: Heart Failure, 9, pp. 146-157. (doi: 10.1016/j.jchf.2020.10.012)

Donin, A. S., Nightingale, C. M., Perkin, M. R., Ussher, M., Jebb, S. A., Landberg, R., Welsh, P., Sattar, N., Adab, P., Owen, C. G., Rudnicka, A. R., Cook, D. G., Whincup, P. H. (2021) Evaluating an intervention to increase cereal fiber intake in children: a randomized controlled feasibility trial. Journal of Nutrition, 151, pp. 379-386. (doi: 10.1093/jn/nxaa347)

Duncan Millar, J., van Wijck, F., Pollock, A., Ali, M. (2021) International consensus recommendations for outcome measurement in poststroke arm rehabilitation trials. European Journal of Physical and Rehabilitation Medicine, 57, pp. 61-68. (doi: 10.23736/S1973-9087.20.06575-2)

Halliday, B. P., Owen, R., Gregson, J., Vassiliou, V., Chen, X., Wage, R., Lota, A. S., Khalique, Z., Tayal, U., Hammersley, D. J., Jones, R. E., Baksi, A. J., Cowie, M. R., Cleland, J. G.F., Pennell, D. J., Prasad, S. K. (2021) Myocardial remodelling after withdrawing therapy for heart failure in patients with recovered dilated cardiomyopathy – insights from TRED‐HF. European Journal of Heart Failure, 23, pp. 293-301. (doi: 10.1002/ejhf.2063)

Docherty, K. F., Campbell, R. T., Brooksbank, K. J.M., Godeseth, R. L., Forsyth, P., McConnachie, A., Roditi, G., Stanley, B., Welsh, P., Jhund, P. S., Petrie, M. C., McMurray, J. J.V. (2021) Rationale and methods of a randomized trial evaluating the effect of neprilysin inhibition on left ventricular remodelling. ESC Heart Failure, 8, pp. 129-138. (doi: 10.1002/ehf2.13137)

Platz, E., Jhund, P. S. (2021) Risk stratification in patients presenting with acute heart failure. European Heart Journal: Acute Cardiovascular Care, 10, pp. 113-115. (doi: 10.1093/ehjacc/zuab005)

Al Ozairi, E., Alroudhan, D., Alsaeed, D., Voase, N., Hasan, A., Gill, J. M.R., Sattar, N., Welsh, P., Gray, C. M., Boonpor, J., Celis-Morales, C., Gray, S. R. (2021) Skeletal muscle and metabolic health – how do we increase muscle mass and function in people with type 2 diabetes. Journal of Clinical Endocrinology and Metabolism, 106, pp. 309-317. (doi: 10.1210/clinem/dgaa835)

Gill, D., Cameron, A. C., Burgess, S., Liu, X., Doherty, D. J., Karhunen, V., Abdul-Rahim, A., Taylor-Rowan, M., Zuber, V., Tsao, P. S., Klarin, D., VA Million Veteran Program, , Evangelou, E., Elliott, P., Damrauer, S. M., Quinn, T. J., Dehghan, A., Theodoratou, E., Dawson, J., Tzoulaki, I. (2021) Urate, blood pressure, and cardiovascular disease: evidence from Mendelian randomization and meta-analysis of clinical trials. Hypertension, 77, pp. 383-392. (doi: 10.1161/HYPERTENSIONAHA.120.16547)

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Samuel, N. A., Cuthbert, J. J., Brown, O. I., Kazmi, S., Cleland, J. G.F., Rigby, A. S., Clark, A. L. (2021) Relation between thyroid function and mortality in patients with chronic heart failure. American Journal of Cardiology, 139, pp. 57-63. (doi: 10.1016/j.amjcard.2020.10.034)

Teerlink, J. R. et al. (2021) Cardiac myosin activation with omecamtiv mecarbil in systolic heart failure. New England Journal of Medicine, 384, pp. 105-116. (doi: 10.1056/NEJMoa2025797)

Bekfani, T., Fudim, M., Cleland, J. G.F., Jorbenadze, A., Haehling, S., Lorber, A., Rothman, A. M.‐K., Stein, K., Abraham, W. T., Sievert, H., Anker, S. D. (2021) A current and future outlook on upcoming technologies in the remote monitoring of patients with heart failure. European Journal of Heart Failure, 23, pp. 175-185. (doi: 10.1002/ejhf.2033)

MacRae, C., Henderson, D. A.G., Mercer, S. W., Burton, J., De Sousa, N., Grill, P., Marwick, C., Guthrie, B. (2021) Excessive polypharmacy and potentially inappropriate prescribing in 147 care homes: a cross-sectional study. BJGP Open, 5, pp. BJGPO.2021.0167. (doi: 10.3399/BJGPO.2021.0167)

Davison, B. A., Senger, S., Sama, I. E., Koch, G. G., Mebazaa, A., Dickstein, K., Samani, N. J., Metra, M., Anker, S. D., Cleland, J. G., Ng, L. L., Mordi, I. R., Zannad, F., Filippatos, G. S., Hillege, H. L., Ponikowski, P., Veldhuisen, D. J., Lang, C. C., Meer, P., Núñez, J., Bayés‐Genís, A., Edwards, C., Voors, A. A., Cotter, G. (2021) Is acute heart failure a distinctive disorder? An analysis from BIOSTAT‐CHF. European Journal of Heart Failure, 23, pp. 43-57. (doi: 10.1002/ejhf.2077)

McCallum, L., Brooksbank, K., McConnachie, A., Aman, A., Lip, S., Dawson, J., MacIntyre, I. M., MacDonald, T. M., Webb, D. J., Padmanabhan, S. (2021) Rationale and design of the genotype-blinded trial of torasemide for the treatment of hypertension (BHF UMOD) American Journal of Hypertension, 34, pp. 92-99. (doi: 10.1093/ajh/hpaa166)

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Grill, P., Marwick, C., De Souza, N., Burton, J. K., Hughes, C., Guthrie, B. (2021) The burden of psychotropic and anticholinergic medicines use in care homes: population-based analysis in 147 care homes. Age and Ageing, 50, pp. 183-189. (doi: 10.1093/ageing/afaa122)

Anderson, J. J., Welsh, P., Ho, F. K., Ferguson, L. D., Welsh, C. E., Pellicori, P., Cleland, J. G.F., Forbes, J., Iliodromiti, S., Boyle, J., Lindsay, R., Celis-Morales, C., Gray, S. R., Katikireddi, S. V., Gill, J. M. R., Pell, J. P., Sattar, N. (2021) Ethnic differences in prevalence of actionable HbA1c levels in UK Biobank: implications for screening. BMJ Open Diabetes Research and Care, 9, (doi: 10.1136/bmjdrc-2021-002176)

Farina, N., Suemoto, C. K., Burton, J. K., Oliveira, D., Frost, R. (2021) Perceptions of dementia amongst the general public across Latin America: a systematic review. Aging and Mental Health, 25, pp. 787-796. (doi: 10.1080/13607863.2020.1725738)

Wijkman, M. O., Malachias, M. V.B., Claggett, B. L., Cheng, S., Matsushita, K., Shah, A. M., Jhund, P. S., Coresh, J., Solomon, S. D., Vardeny, O. (2021) Resistance to antihypertensive treatment and long-term risk: The Atherosclerosis Risk in Communities study. Journal of Clinical Hypertension, 23, pp. 1887-1896. (doi: 10.1111/jch.14269)

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2020

Brown, R., Welsh, P., Logue, J. (2020) Systematic review of clinical guidelines for lipid-lowering in the secondary prevention of cardiovascular disease events. Open Heart, 7, (doi: 10.1136/openhrt-2020-001396)

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Ferreira, J. P., Docherty, K. F., Stienen, S., Jhund, P. S., Claggett, B. L., Solomon, S. D., Petrie, M. C., Gregsone, J., Pocock, S. L., Zannad, F., McMurray, J. (2020) Estimating the lifetime benefits of treatments for heart failure. JACC: Heart Failure, 8, pp. 984-995. (doi: 10.1016/j.jchf.2020.08.004)

Kristensen, S. L., Castagno, D., Shen, L., Jhund, P., Docherty, K., Rørth, R., Abraham, W. T., Desai, A., Dickstein, K., Rouleau, J. L., Zile, M. R., Swedberg, K., Packer, M., Solomon, S. D., Køber, L., McMurray, J. J.V. (2020) Prevalence and incidence of intra-ventricular conduction delays and outcomes in patients with heart failure and reduced ejection fraction: insights from PARADIGM‐HF and ATMOSPHERE. European Journal of Heart Failure, 22, pp. 2370-2379. (doi: 10.1002/ejhf.1972)

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Mackenzie, I. S. et al. (2020) Long-term cardiovascular safety of febuxostat compared with allopurinol in patients with gout (FAST): a multicentre, prospective, randomised, open-label, non-inferiority trial. Lancet, 396, pp. 1745-1757. (doi: 10.1016/S0140-6736(20)32234-0)

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Ho, F. K., Gray, S. R., Welsh, P., Petermann-Rocha, F., Foster, H., Waddell, H., Anderson, J., Lyall, D., Sattar, N., Gill, J. M.R., Mathers, J. C., Pell, J. P., Celis-Morales, C. (2020) Associations of fat and carbohydrate intake with cardiovascular disease and mortality: prospective cohort study of UK Biobank participants. British Medical Journal, 368, (doi: 10.1136/bmj.m688)

Shen, L., Jhund, P., McMurray, J. (2020) Dyslipidaemia, a factor worthy of adjustment: reply. European Journal of Heart Failure, 22, pp. 564-565. (doi: 10.1002/ejhf.1718)

Tromp, J., Bamadhaj, S., Cleland, J. G.F., Angermann, C. E., Dahlstrom, U., Ouwerkerk, W., Tay, W. T., Dickstein, K., Ertl, G., Hassanein, M., Hu, D., Perrone, S. V., Ghadanfar, M., Schweizer, A., Obergfell, A., Lam, C. S.P., Filippatos, G., Collins, S. P. (2020) Post-discharge prognosis of patients admitted to hospital for heart failure by world region, and national level of income and income disparity (REPORT-HF): a cohort study. Lancet Global Health, 8, pp. e411-e422. (doi: 10.1016/S2214-109X(20)30004-8)

Docherty, K. F., Shen, L., Castagno, D., Petrie, M. C., Abraham, W. T., Böhm, M., Desai, A. S., Dickstein, K., Køber, L. V., Packer, M., Rouleau, J. L., Solomon, S. D., Swedberg, K., Vazir, A., Zile, M. R., Jhund, P. S., McMurray, J. J.V. (2020) Relationship between heart rate and outcomes in patients in sinus rhythm or atrial fibrillation with heart failure and reduced ejection fraction. European Journal of Heart Failure, 22, pp. 528-538. (doi: 10.1002/ejhf.1682)

Santema, B. T., Chan, M. M.Y., Tromp, J., Dokter, M., van der Wal, H. H., Emmens, J. E., Takens, J., Samani, N. J., Ng, L. L., Lang, C. C., van der Meer, P., ter Maaten, J. M., Damman, K., Dickstein, K., Cleland, J. G., Zannad, F., Anker, S. D., Metra, M., van der Harst, P., de Boer, R. A., van Veldhuisen, D. J., Rienstra, M., Lam, C. S.P., Voors, A. A. (2020) The influence of atrial fibrillation on the levels of NT-proBNP versus GDF-15 in patients with heart failure. Clinical Research in Cardiology, 109, pp. 331-338. (doi: 10.1007/s00392-019-01513-y)

Serenelli, M., Jackson, A., Dewan, P., Jhund, P. S., Petrie, M. C., Rossignol, P., Campo, G., Pitt, B., Zannad, F., Ferreira, J. P., McMurray, J. J.V. (2020) Mineralocorticoid receptor antagonists, blood pressure, and outcomes in heart failure with reduced ejection fraction. JACC: Heart Failure, 8, pp. 188-198. (doi: 10.1016/j.jchf.2019.09.011)

Rorth, R., Jhund, P. S., Yilmaz, M. B., Kristensen, S. L., Welsh, P., Desai, A. S., Køber, L., Prescott, M. F., Rouleau, J. L., Solomon, S. D., Swedberg, K., Zile, M. R., Packer, M., McMurray, J. J.V. (2020) Comparison of BNP and NT-proBNP in patients with heart failure and reduced ejection fraction. Circulation: Heart Failure, 13, (doi: 10.1161/CIRCHEARTFAILURE.119.006541)

McMurray, J. J.V. et al. (2020) Effects of Sacubitril-Valsartan, versus Valsartan, in Women Compared to Men with Heart Failure and Preserved Ejection Fraction: Insights from PARAGON-HF. Circulation, 141, pp. 338-351. (doi: 10.1161/CIRCULATIONAHA.119.044491)

Maznyczka, A. M., McCartney, P. J., Oldroyd, K. G., Lindsay, M., McEntegart, M., Eteiba, H., Rocchiccioli, P., Good, R., Shaukat, A., Robertson, K., Kodoth, V., Greenwood, J. P., Cotton, J. M., Hood, S., Watkins, S., Macfarlane, P. W., Kennedy, J., Tait, C., Welsh, P., Sattar, N., Collison, D., Gillespie, L., McConnachie, A., Berry, C. (2020) Effects of intracoronary alteplase on microvascular function in acute myocardial infarction. Journal of the American Heart Association, 9, (doi: 10.1161/JAHA.119.014066)

Cameron, A. C., Welsh, P., Neves, K. B., Newby, D., Touyz, R. M., Lang, N. (2020) Acute vascular effects of vascular endothelial growth factor inhibition in the forearm arterial circulation. Journal of Hypertension, 38, pp. 257-265. (doi: 10.1097/HJH.0000000000002230)

Seferović, P. M. et al. (2020) European Society of Cardiology/Heart Failure Association position paper on the role and safety of new glucose‐lowering drugs in patients with heart failure. European Journal of Heart Failure, 22, pp. 196-213. (doi: 10.1002/ejhf.1673)

Bégué, C., Mörner, S., Brito, D., Hengstenberg, C., Cleland, J. G.F., Arbustini, E., Galve, E., Wichter, T., Richter, A., Golmard, J.-L., Bernard, M., Dubourg, O., Komajda, M., Charron, P., Isnard, R. (2020) Mid-regional proatrial natriuretic peptide for predicting prognosis in hypertrophic cardiomyopathy. Heart, 106, pp. 196-202. (doi: 10.1136/heartjnl-2019-314826)

Jhund, P. S. (2020) The recurring problem of heart failure hospitalisations. European Journal of Heart Failure, 22, pp. 249-250. (doi: 10.1002/ejhf.1721)

Welsh, C., Welsh, P., Celis Morales, C. A., Mark, P., Mackay, D., Ghouri, N., Ho, F., Ferguson, L. D., Brown, R., Lewsey, J., Cleland, J. G., Gray, S. R., Lyall, D. M., Anderson, J., Jhund, P. S., Pell, J., McGuire, D. K., Gill, J. M.R., Sattar, N. (2020) Glycated hemoglobin, prediabetes and the links to cardiovascular disease: data from UK Biobank. Diabetes Care, 43, pp. 440-445. (doi: 10.2337/dc19-1683)

Kosiborod, M. N., Jhund, P., Docherty, K. F., Diez, M., Petrie, M. C., Verma, S., Nicolau, J. C., Merkely, B., Kitakaze, M., DeMets, D. L., Inzucchi, S. E., Køeber, L., Martinez, F. A., Ponikowski, P., Sabatine, M. S., Solomon, S. D., Bengtsson, O., Lindholm, D., Niklasson, A., Sjöstrand, M., Langkilde, A. M., McMurray, J. J.V. (2020) Effects of dapagliflozin on symptoms, function and quality of life in patients with heart failure and reduced ejection fraction: results from the DAPA-HF trial. Circulation, 141, pp. 90-99. (doi: 10.1161/CIRCULATIONAHA.119.044138)

Martinez, F. A., Serenelli, M., Nicolau, J. C., Petrie, M. C., Chiang, C.-E., Tereshchenko, S., Solomon, S. D., Inzucchi, S. E., Køber, L., Kosiborod, M. N., Ponikowski, P., Sabatine, M. S., DeMets, D. L., Dutkiewicz-Piasecka, M., Bengtsson, O., Sjöstrand, M., Langkilde, A. M., Jhund, P., McMurray, J. J.V. (2020) Efficacy and safety of dapagliflozin in heart failure with reduced ejection fraction according to age: insights from DAPA-HF. Circulation, 141, pp. 100-111. (doi: 10.1161/CIRCULATIONAHA.119.044133)

Filippatos, G., Angermann, C. E., Cleland, J. G.F., Lam, C. S.P., Dahlström, U., Dickstein, K., Ertl, G., Hassanein, M., Hart, K. W., Lindsell, C. J., Perrone, S. V., Guerin, T., Ghadanfar, M., Schweizer, A., Obergfell, A., Collins, S. P. (2020) Global differences in characteristics, precipitants, and initial management of patients presenting with acute heart failure. JAMA Cardiology, 5, pp. 401-410. (doi: 10.1001/jamacardio.2019.5108)

Ferreira, J. P., Ouwerkerk, W., Tromp, J., Ng, L., Dickstein, K., Anker, S., Filippatos, G., Cleland, J. G., Metra, M., van Veldhuisen, D. J., Voors, A. A., Zannad, F. (2020) Cardiovascular and non‐cardiovascular death distinction: the utility of troponin beyond N‐terminal pro‐B‐type natriuretic peptide. Findings from the BIOSTAT‐CHF study. European Journal of Heart Failure, 22, pp. 81-89. (doi: 10.1002/ejhf.1654)

Pellicori, P., Cleland, J. G.F., Clark, A. L. (2020) Chronic obstructive pulmonary disease and heart failure: a breathless conspiracy. Heart Failure Clinics, 16, pp. 33-44. (doi: 10.1016/j.hfc.2019.08.003)

Nikolaidou, T., Samuel, N. A., Marincowitz, C., Fox, D. J., Cleland, J. G.F., Clark, A. L. (2020) Electrocardiographic characteristics in patients with heart failure and normal ejection fraction: a systematic review and meta‐analysis. Annals of Noninvasive Electrocardiology, 25, (doi: 10.1111/anec.12710)

Kobayashi, M., Voors, A. A., Girerd, N., Billotte, M., Anker, S. D., Cleland, J. G., Lang, C. C., Ng, L. L., van Veldhuisen, D. J., Dickstein, K., Metra, M., Duarte, K., Rossignol, P., Zannad, F., Ferreira, J. P. (2020) Heart failure etiologies and clinical factors precipitating for worsening heart failure: Findings from BIOSTAT-CHF. European Journal of Internal Medicine, 71, pp. 62-69. (doi: 10.1016/j.ejim.2019.10.017)

Pellicori, P., Zhang, J., Cuthbert, J., Urbinati, A., Shah, P., Kazmi, S., Clark, A. L., Cleland, J. G.F. (2020) High sensitivity C-reactive protein in chronic heart failure: patient characteristics, phenotypes, and mode of death. Cardiovascular Research, 116, pp. 91-100. (doi: 10.1093/cvr/cvz198)

Pellicori, P., Khan, M. J. I., Graham, F. J., Cleland, J. G.F. (2020) New perspectives and future directions in the treatment of heart failure. Heart Failure Reviews, 25, pp. 147-159. (doi: 10.1007/s10741-019-09829-7)

Cao, T. H., Jones, D. J.L., Voors, A. A., Quinn, P. A., Sandhu, J. K., Chan, D. C.S., Parry, H. M., Mohan, M., Mordi, I. R., Sama, I. E., Anker, S. D., Cleland, J. G., Dickstein, K., Filippatos, G., Hillege, H. L., Metra, M., Ponikowski, P., Samani, N. J., Van Veldhuisen, D. J., Zannad, F., Lang, C. C., Ng, L. L. (2020) Plasma proteomic approach in patients with heart failure: insights into pathogenesis of disease progression and potential novel treatment targets. European Journal of Heart Failure, 22, pp. 70-80. (doi: 10.1002/ejhf.1608)

Kao, D., Purohit, S., Jhund, P. (2020) Therapeutic futility and phenotypic heterogeneity in heart failure with preserved ejection fraction: what is the role of bionic learning? European Journal of Heart Failure, 22, pp. 159-161. (doi: 10.1002/ejhf.1658)

Anker, M. S., Hülsmann, M., Cleland, J. G. (2020) What do patients with heart failure die from? A single assassin or a conspiracy? European Journal of Heart Failure, 22, pp. 26-28. (doi: 10.1002/ejhf.1689)

Coll, A. P. et al. (2020) GDF15 mediates the effects of metformin on body weight and energy balance. Nature, 578, pp. 444-448. (doi: 10.1038/s41586-019-1911-y)

Israr, M. Z. et al. (2020) Implications of serial measurements of natriuretic peptides in heart failure: insights from BIOSTAT‐CHF. European Journal of Heart Failure, 22, pp. 1486-1490. (doi: 10.1002/ejhf.1951)

McCartney, P. J., Maznyczka, A. M., Eteiba, H., McEntegart, M., Oldroyd, K. G., Greenwood, J. P., Mareida, N., Schmitt, M., McCann, G. P., Fairbairn, T., McAlindon, E., Tait, C., Welsh, P., Sattar, N., Orchard, V., Corcoran, D., Ford, T. J., Radjenovic, A., Ford, I., McConnachie, A., Berry, C. (2020) Low-dose alteplase during primary percutaneous coronary intervention according to ischemic time. Journal of the American College of Cardiology, 75, pp. 1406-1421. (doi: 10.1016/j.jacc.2020.01.041)

Brady, M. C. et al. (2020) RELEASE: a protocol for a systematic review based, individual participant data, meta- and network meta-analysis, of complex speech-language therapy interventions for stroke-related aphasia. Aphasiology, 34, pp. 137-157. (doi: 10.1080/02687038.2019.1643003)

2019

Kotecha, D., Gill, S. K., Flather, M. D., Holmes, J., Packer, M., Rosano, G., Böhm, M., McMurray, J. J.V., Wikstrand, J., Anker, S. D., van Veldhuisen, D. J., Manzano, L., von Lueder, T. G., Rigby, A. S., Andersson, B., Kjekshus, J., Wedel, H., Ruschitzka, F., Cleland, J. G.F., Damman, K., Redon, J., Coats, A. J.S. (2019) Impact of renal impairment on beta-blocker efficacy in patients with heart failure. Journal of the American College of Cardiology, 74, pp. 2893-2904. (doi: 10.1016/j.jacc.2019.09.059)

Dewan, P., Rorth, R., Raparelli, V., Campbell, R. T., Shen, L., Jhund, P. S., Petrie, M. C., Anand, I. S., Carson, P. E., Desai, A. S., Granger, C. B., Køber, L., Komajda, M., McKelvie, R. S., O'Meara, E., Pfeffer, M. A., Pitt, B., Solomon, S. D., Swedberg, K., Zile, M. R., McMurray, J. J.V. (2019) Sex-related differences in heart failure with preserved ejection fraction. Circulation: Heart Failure, 12, (doi: 10.1161/CIRCHEARTFAILURE.119.006539)

Teumer, A. et al. (2019) KCND3 potassium channel gene variant confers susceptibility to electrocardiographic early repolarization pattern. JCI Insight, 4, (doi: 10.1172/jci.insight.131156)

Ferguson, L. D., Brown, R., Celis-Morales, C., Welsh, P., Lyall, D. M., Pell, J. P., McInnes, I. B., Siebert, S., Sattar, N. (2019) Association of central adiposity with psoriasis, psoriatic arthritis and rheumatoid arthritis: a cross-sectional study of the UK Biobank. Rheumatology, 58, pp. 2137-2142. (doi: 10.1093/rheumatology/kez192)

Eastwood, S. V., Chaturvedi, N., Sattar, N., Welsh, P. I., Hughes, A. D., Tillin, T. (2019) Impact of kidney function on cardiovascular risk and mortality: a comparison of South Asian and European cohorts. American Journal of Nephrology, 50, pp. 425-433. (doi: 10.1159/000503873)

Johnson, M. J., Cockayne, S., Currow, D. C., Bell, K., Hicks, K., Fairhurst, C., Gabe, R., Torgerson, D., Jefferson, L., Oxberry, S., Ghosh, J., Hogg, K. J., Murphy, J., Allgar, V., Cleland, J. G.F., Clark, A. L. (2019) Oral modified release morphine for breathlessness in chronic heart failure: a randomised placebo-controlled trial. ESC Heart Failure, 6, pp. 1149-1160. (doi: 10.1002/ehf2.12498)

Cameron, A. C., Lang, N. N., Dominiczak, A. F., Jennings, G. L.R., Batlle, D., Bursztyn, M., Chugh, A. R., Floras, J. S., Taler, S. J., Touyz, R. M., Delles, C. (2019) Progressive hypertension and severe left ventricular outflow tract obstruction. Hypertension, 74, pp. 1216-1225. (doi: 10.1161/hypertensionaha.119.13343)

Sharma, V. et al. (2019) Report from the Annual Conference of the British Society of Echocardiography, November 2017, Edinburgh International Conference Centre, Edinburgh. Echo Research and Practice, 6, pp. M1-M2. (doi: 10.1530/ERP-19-0056)

Jackson, A. M., Jhund, P. S. (2019) The price of a failing heart. European Journal of Heart Failure, 21, pp. 1532-1533. (doi: 10.1002/ejhf.1605)

Mehra, M. R., Vaduganathan, M., Fu, M., Ferreira, J. P., Anker, S. A., Cleland, J. G.F., Lam, C. S.P., van Veldhuisen, D. J., Byra, W. M., Spiro, T., Deng, H., Zannad, F., Greenberg, B. (2019) A comprehensive analysis of the effects of rivaroxaban on stroke or transient ischaemic attack in patients with heart failure, coronary artery disease, and sinus rhythm: the COMMANDER HF trial. European Heart Journal, 40, pp. 3593-3602. (doi: 10.1093/eurheartj/ehz427)

McMurray, J. J.V. et al. (2019) Dapagliflozin in patients with heart failure and reduced ejection fraction. New England Journal of Medicine, 381, pp. 1995-2008. (doi: 10.1056/NEJMoa1911303)

Tillin, T., Tuson, C., Sowa, B., Chattopadhyay, K., Sattar, N., Welsh, P., Roberts, I., Ebrahim, S., Kinra, S., Hughes, A., Chaturvedi, N. (2019) Yoga and Cardiovascular Health Trial (YACHT): a UK-based randomised mechanistic study of a yoga intervention plus usual care versus usual care alone following an acute coronary event. BMJ Open, 9, (doi: 10.1136/bmjopen-2019-030119)

Sillars, A., Celis-Morales, C. A., Ho, F., Petermann, F., Welsh, P., Iliodromiti, S., Ferguson, L. D., Lyall, D. M., Anderson, J., Mackay, D., Pellicori, P., Cleland, J., Pell, J. P., Gill, J. M.R., Gray, S. R., Sattar, N. (2019) Association of fitness and grip-strength with heart failure: findings from the UK Biobank population-based study. Mayo Clinic Proceedings, 94, pp. 2230-2240. (doi: 10.1016/j.mayocp.2019.04.041)

Steell, L., Ho, F. K., Sillars, A., Petermann, F., Li, H., Lyall, D. M., Iliodromiti, S., Welsh, P., Anderson, J., Mackay, D. F., Pell, J. P., Sattar, N., Gill, J. M.R., Gray, S. R., Celis-Morales, C. A. (2019) Dose-response associations of cardiorespiratory fitness with all-cause mortality and incidence and mortality of cancer and cardiovascular and respiratory diseases: the UK Biobank cohort study. British Journal of Sports Medicine, 53, pp. 1371-1378. (doi: 10.1136/bjsports-2018-099093)

Ferguson, L., Welsh, P., Brown, R., Tindell, A., Kerrigan, S., Sattar, N., McInnes, I., Siebert, S. (2019) Effect of Phosphodiesterase 4 Inhibition with Apremilast on Cardiometabolic Outcomes in Psoriatic Arthritis – Initial Results from the Immune Metabolic Associations in Psoriatic Arthritis (IMAPA) Study.

Lees, J. S., Welsh, C. E., Celis-Morales, C. A., Mackay, D., Lewsey, J., Gray, S. R., Lyall, D. M., Cleland, J. G., Gill, J. M.R., Jhund, P. S., Pell, J., Sattar, N., Welsh, P., Mark, P. B. (2019) Glomerular filtration rate by differing measures, albuminuria and prediction of cardiovascular disease, mortality and end-stage kidney disease. Nature Medicine, 25, pp. 1753-1760. (doi: 10.1038/s41591-019-0627-8)

Beusekamp, J. C., Tromp, J., Cleland, J. G.F., Givertz, M. M., Metra, M., O’Connor, C. M., Teerlink, J. R., Ponikowski, P., Ouwerkerk, W., van Veldhuisen, D. J., Voors, A. A., van der Meer, P. (2019) Hyperkalemia and treatment with RAAS inhibitors during acute heart failure hospitalizations and their association with mortality. JACC: Heart Failure, 7, pp. 970-979. (doi: 10.1016/j.jchf.2019.07.010)

Pellicori, P., Urbinati, A., Kaur, K., Zhang, J., Shah, P., Kazmi, S., Capucci, A., Cleland, J. G.F., Clark, A. L. (2019) Prevalence and incidence of atrial fibrillation in ambulatory patients with heart failure. American Journal of Cardiology, 124, pp. 1554-1560. (doi: 10.1016/j.amjcard.2019.08.018)

Conrad, N., Judge, A., Canoy, D., Tran, J., Pinho-Gomes, A. C., Millett, E. R.C., Salimi-Khorshidi, G., Cleland, J. G., McMurray, J. J.V., Rahimi, K. (2019) Temporal trends and patterns in mortality after incident heart failure: a longitudinal analysis of 86 000 individuals. JAMA Cardiology, 4, pp. 1102-1111. (doi: 10.1001/jamacardio.2019.3593)

Beldhuis, I. E., Streng, K. W., van der Meer, P., Ter Maaten, J. M., O'Connor, C. M., Metra, M., Dittrich, H. C., Ponikowski, P., Cotter, G., Cleland, J. G.F., Davison, B. A., Givertz, M. M., Teerlink, J. R., Bloomfield, D. M., Voors, A. A., Damman, K. (2019) Trajectories of changes in renal function in patients with acute heart failure. Journal of Cardiac Failure, 25, pp. 866-874. (doi: 10.1016/j.cardfail.2019.07.004)

Clark, D. W. et al. (2019) Associations of autozygosity with a broad range of human phenotypes. Nature Communications, 10, (doi: 10.1038/s41467-019-12283-6)

Schmidt, A. F. et al. (2019) Phenome-wide association analysis of LDL-cholesterol lowering genetic variants in PCSK9. BMC Cardiovascular Disorders, 19, (doi: 10.1186/s12872-019-1187-z)

Solomon, S. D. et al. (2019) Angiotensin–neprilysin inhibition in heart failure with preserved ejection fraction. New England Journal of Medicine, 381, pp. 1609-1620. (doi: 10.1056/NEJMoa1908655)

Selvaraj, S., Claggett, B., Pozzi, A., McMurray, J. J.V., Jhund, P. S., Packer, M., Desai, A. S., Lewis, E. F., Vaduganathan, M., Lefkowitz, M. P., Rouleau, J. L., Shi, V. C., Zile, M. R., Swedberg, K., Solomon, S. D. (2019) Prognostic implications of congestion on physical examination among contemporary patients with heart failure and reduced ejection fraction: PARADIGM-HF. Circulation, 140, pp. 1369-1379. (doi: 10.1161/CIRCULATIONAHA.119.039920)

Menni, C., McCallum, L., Pietzner, M., Zierer, J., Aman, A., Suhre, K., Mohney, R. P., Mangino, M., Friedrich, N., Spector, T. D., Padmanabhan, S. (2019) Metabolomic profiling identifies novel associations with electrolyte and acid-base homeostatic patterns. Scientific Reports, 9, (doi: 10.1038/s41598-019-51492-3)

Santema, B. T. et al. (2019) Identifying optimal doses of heart failure medications in men compared with women: a prospective, observational, cohort study. Lancet, 394, (doi: 10.1016/S0140-6736(19)31792-1)

Tin, A. et al. (2019) Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels. Nature Genetics, 51, pp. 1459-1474. (doi: 10.1038/s41588-019-0504-x)

McDicken, J. A., Elliott, E., Blayney, G., Makin, S., Ali, M., Larner, A. J., Quinn, T. J. (2019) Accuracy of the short-form Montreal Cognitive Assessment: systematic review and validation. International Journal of Geriatric Psychiatry, 34, pp. 1515-1525. (doi: 10.1002/gps.5162)

Howlett, J. G., Stebbins, A., Petrie, M. C., Jhund, P. S., Castelvecchio, S., Cherniavsky, A., Sueta, C. A., Roy, A., Piña, I. L., Wurm, R., Drazner, M. H., Andersson, B., Batlle, C., Senni, M., Chrzanowski, L., Merkely, B., Carson, P., Desvigne-Nickens, P. M., Lee, K. L., Velazquez, E. J., Al-Khalidi, H. R. (2019) CABG improves outcomes in patients with ischemic cardiomyopathy 10-year follow-up of the STICH trial. JACC: Heart Failure, 7, pp. 878-887. (doi: 10.1016/j.jchf.2019.04.018)

Seferovic, P. M. et al. (2019) Clinical practice update on heart failure 2019: pharmacotherapy, procedures, devices and patient management. An expert consensus meeting report of The Heart Failure Association of the European Society of Cardiology. European Journal of Heart Failure, 21, pp. 1169-1186. (doi: 10.1002/ejhf.1531)

Muilwijk, M., Ho, F., Waddell, H., Sillars, A., Welsh, P., Iliodromiti, S., Brown, R., Ferguson, L., Stronks, K., van Valkengoed, I., Pell, J. P., Gray, S. R., Gill, J. M. R., Sattar, N., Celis-Morales, C. (2019) Contribution of type 2 diabetes to all-cause mortality, cardiovascular disease incidence and cancer incidence in white Europeans and South Asians: findings from the UK Biobank population-based cohort study. BMJ Open Diabetes Research and Care, 7, (doi: 10.1136/bmjdrc-2019-000765)

Lip, S., Tan, L. E., Jeemon, P., McCallum, L., Dominiczak, A. F., Padmanabhan, S. (2019) Diastolic blood pressure J-curve phenomenon in a tertiary-care hypertension clinic. Hypertension, 74, pp. 767-775. (doi: 10.1161/HYPERTENSIONAHA.119.12787)

Yazaki, Y., Salzano, A., Nelson, C. P., Voors, A. A., Anker, S. D., Cleland, J. G., Lang, C. C., Metra, M., Samani, N. J., Ng, L. L., Suzuki, T. (2019) Geographical location affects the levels and association of trimethylamine N‐oxide with heart failure mortality in BIOSTAT‐CHF: a post‐hoc analysis. European Journal of Heart Failure, 21, pp. 1291-1294. (doi: 10.1002/ejhf.1550)

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2018

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Rush, C. J., Campbell, R. T., Jhund, P. S., Petrie, M. C., McMurray, J. J.V. (2018) Association is not causation: treatment effects cannot be estimated from observational data in heart failure. European Heart Journal, 39, pp. 3417-3438. (doi: 10.1093/eurheartj/ehy407)

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Stewart, R. A.H., Szalewska, D., Stebbins, A., Al-Khalidi, H. R., Cleland, J. G.H., Rynkiewicz, A., Drazner, M. H., White, H. D., Mark, D. B., Roy, A., Kosevic, D., Rajda, M., Jasinski, M., Leng, C. Y., Tungsubutra, W., Desvigne-Nickens, P., Velazquez, E. J., Petrie, M. C. (2018) Six-minute walk distance after coronary artery bypass grafting compared with medical therapy in ischaemic cardiomyopathy. Open Heart, 5, (doi: 10.1136/openhrt-2017-000752)

ter Maaten, J. M., Voors, A. A., Damman, K., van der Meer, P., Anker, S. D., Cleland, J. G.F., Dickstein, K., Filippatos, G., van der Harst, P., Hillege, H. L., Lang, C. C., Metra, M., Navis, G., Ng, L., Ouwerkerk, W., Ponikowski, P., Samani, N. J., van Veldhuisen, D. J., Zannad, F., Zwinderman, A. H., de Borst, M. H. (2018) Fibroblast growth factor 23 is related to profiles indicating volume overload, poor therapy optimization and prognosis in patients with new-onset and worsening heart failure. International Journal of Cardiology, 253, pp. 84-90. (doi: 10.1016/j.ijcard.2017.10.010)

Lean, M. E.J. et al. (2018) Primary care-led weight management for remission of type 2 diabetes (DiRECT): an open-label, cluster-randomised trial. Lancet, 391, pp. 541-551. (doi: 10.1016/S0140-6736(17)33102-1)

Conrad, N., Judge, A., Tran, J., Mohseni, H., Hedgecott, D., Crespillo, A. P., Allison, M., Hemingway, H., Cleland, J. G., McMurray, J. J.V., Rahimi, K. (2018) Temporal trends and patterns in heart failure incidence: a population-based study of 4 million individuals. Lancet, 391, pp. 10-16. (doi: 10.1016/S0140-6736(17)32520-5)

Corcoran, D., Young, R., Cialdella, P., McCartney, P., Bajrangee, A., Hennigan, B., Collison, D., Carrick, D., Shaukat, A., Good, R., Watkins, S., McEntegart, M., Watt, J., Welsh, P., Sattar, N., McConnachie, A., Oldroyd, K.G., Berry, C. (2018) The effects of remote ischaemic preconditioning on coronary artery function in patients with stable coronary artery disease. International Journal of Cardiology, 252, pp. 24-30. (doi: 10.1016/j.ijcard.2017.10.082)

Magnus, M. C., Lawlor, D. A., Iliodromiti, S., Padmanabhan, S., Nelson, S. M., Fraser, A. (2018) Age at menarche and cardiometabolic health: a sibling analysis in the Scottish Family Health Study. Journal of the American Heart Association, 7, (doi: 10.1161/JAHA.117.007780)

Welsh, P. (2018) Correlating changes in metabolic status with arterial health: modest associations but any clinical implications? Hypertension, 71, pp. 227-228. (doi: 10.1161/HYPERTENSIONAHA.117.10595)

Rørth, R., Fosbøl, E. L., Mogensen, U. M., Kragholm, K., Numé, A.-k., Gislason, G. H.,, Jhund, P. S., Petrie, M. C., McMurray, J. J.V., Torp-Pedersen, C., Køber, L., Kristensen, S. L. (2018) Employment status at time of first hospitalization for heart failure is associated with death and rehospitalization for heart failure. European Journal of Heart Failure, 20, pp. 240-247. (doi: 10.1002/ejhf.1046)

Cleland, J. G.F. (2018) Physicians Addicted to Prescribing Aspirin-a Disorder Of Cardiologists (PAPA-DOC) Syndrome: the headache of nonevidence-based medicine for ischemic heart disease? JACC: Heart Failure, 6, pp. 168-171. (doi: 10.1016/j.jchf.2017.11.014)

Platz, E., Jhund, P. S., Claggett, B. L., Pfeffer, M. A., Swedberg, K., Granger, C. B., Yusuf, S., Solomon, S. D., McMurray, J. J. (2018) Prevalence and prognostic importance of precipitating factors leading to heart failure hospitalization: recurrent hospitalizations and mortality. European Journal of Heart Failure, 20, pp. 295-303. (doi: 10.1002/ejhf.901)

Nikolaidou, T., Pellicori, P., Zhang, J., Kazmi, S., Goode, K. M., Cleland, J. G., Clark, A. L. (2018) Prevalence, predictors, and prognostic implications of PR interval prolongation in patients with heart failure. Clinical Research in Cardiology, 107, pp. 108-119. (doi: 10.1007/s00392-017-1162-6)

Welsh, P., Kou, L., Yu, C., Anand, I., van Veldhuisen, D. J., Maggioni, A. P., Desai, A. S., Solomon, S. D., Pfeffer, M. A., Cheng, S., Gullestad, L., Aukrust, P., Ueland, T., Swedberg, K., Young, J. B., Kattan, M. W., Sattar, N., McMurray, J. J.V. (2018) Prognostic importance of emerging cardiac, inflammatory, and renal biomarkers in chronic heart failure patients with reduced ejection fraction and anaemia: RED-HF study. European Journal of Heart Failure, 20, pp. 268-277. (doi: 10.1002/ejhf.988)

Emmens, J. E., Jones, D. J.L., Cao, T. H., Chan, D. C.S., Romaine, S. P.R., Quinn, P. A., Anker, S. D., Cleland, J. G., Dickstein, K., Filippatos, G., Hillege, H. L., Lang, C. C., Ponikowski, P., Samani, N. J., van Veldhuisen, D. J., Zannad, F., Zwinderman, A. H., Metra, M., de Boer, R. A., Voors, A. A., Ng, L. L. (2018) Proteomic diversity of high-density lipoprotein explains its association with clinical outcome in patients with heart failure. European Journal of Heart Failure, 20, pp. 260-267. (doi: 10.1002/ejhf.1101)

Cotter, G., Metra, M., Davison, B. A., Jondeau, G., Cleland, J. G.F., Bourge, R. C., Milo, O., O'Connor, C. M., Parker, J. D., Torre-Amione, G., van Veldhuisen, D. J., Kobrin, I., Rainisio, M., Senger, S., Edwards, C., McMurray, J. J.V., Teerlink, J. R. (2018) Systolic blood pressure reduction during the first 24 h in acute heart failure admission: friend or foe? European Journal of Heart Failure, 20, pp. 317-322. (doi: 10.1002/ejhf.889)

Stoumpos, S., Lees, J., Welsh, P., Hund, M., Geddes, C. C., Nelson, S. M., Mark, P. B. (2018) The utility of anti-Müllerian hormone in women with chronic kidney disease, on haemodialysis and after kidney transplantation. Reproductive BioMedicine Online, 36, pp. 219-226. (doi: 10.1016/j.rbmo.2017.11.003)

Ouwerkerk, W., Zwinderman, A. H., Ng, L. L., Demissei, B., Hillege, H. L., Zannad, F., van Veldhuisen, D. J., Samani, N. J., Ponikowski, P., Metra, M., ter Maaten, J. M., Lang, C. C., van der Harst, P., Filippatos, G., Dickstein, K., Cleland, J. G., Anker, S. D., Voors, A. A. (2018) Biomarker-guided versus guideline-based treatment of patients with heart failure: results from BIOSTAT-CHF. Journal of the American College of Cardiology, 71, pp. 386-398. (doi: 10.1016/j.jacc.2017.11.041)

van der Wardt, V., Burton, J. K., Conroy, S., Welsh, T., Logan, P., Taggar, J., Tanajewski, L., Gladman, J. (2018) Withdrawal of antihypertensive therapy in people with dementia: feasibility study. Pilot and Feasibility Studies, 4, (doi: 10.1186/s40814-017-0221-0)

Cleland, J. G.F., Flather, M. D., Altman, D. G., Kotecha, D. (2018) Reply: an incomplete story. Journal of the American College of Cardiology, 71, pp. 105. (doi: 10.1016/j.jacc.2017.10.078)

Cleland, J. G.F., Bunting, K. V., Flather, M. D., Altman, D. G., Holmes, J., Coats, A. J.S., Manzano, L., McMurray, J. J.V., Ruschitzka, F., van Veldhuisen, D. J., von Lueder, T. G., Böhm, M., Andersson, B., Kjekshus, J., Packer, M., Rigby, A. S., Rosano, G., Wedel, H., Hjalmarson, Å., Wikstrand, J., Kotecha, D. (2018) Beta-blockers for heart failure with reduced, mid-range, and preserved ejection fraction: an individual patient-level analysis of double-blind randomized trials. European Heart Journal, 39, pp. 26-35. (doi: 10.1093/eurheartj/ehx564)

Kristensen, S. L., Mogensen, U. M., Tarnesby, G., Gimpelewicz, C. R., Ali, M. A., Shao, Q., Chiang, Y., Jhund, P. S., Abraham, W. T., Dickstein, K., McMurray, J. J.V., Køber, L. (2018) Aliskiren alone or in combination with enalapril vs. enalapril among patients with chronic heart failure with and without diabetes: a subgroup analysis from the ATMOSPHERE trial. European Journal of Heart Failure, 20, pp. 136-147. (doi: 10.1002/ejhf.896)

Pellicori, P., Urbinati, A., Zhang, J., Joseph, A. C., Costanzo, P., Lukaschuk, E., Capucci, A., Cleland, J. G.F., Clark, A. L. (2018) Clinical and prognostic relationships of pulmonary artery to aorta diameter ratio in patients with heart failure: a cardiac magnetic resonance imaging study. Clinical Cardiology, 41, pp. 20-27. (doi: 10.1002/clc.22840)

Patel, N., Hellmuth, C., Uhl, O., Godfrey, K., Briley, A., Welsh, P., Pasupathy, D., Seed, P., Koletzko, B., Poston, L. (2018) Cord metabolic profiles In obese pregnant women; insights into offspring growth and body composition. Journal of Clinical Endocrinology and Metabolism, 103, pp. 346-355. (doi: 10.1210/jc.2017-00876)

Arba, F., Quinn, T. J., Hankey, G. J., Lees, K. R., Wardlaw, J. M., Ali, M., Inzitari, D. (2018) Enlarged perivascular spaces and cognitive impairment after stroke and transient ischemic attack. International Journal of Stroke, 13, pp. 47-56. (doi: 10.1177/1747493016666091)

Rørth, R., Fosbøl, E. L., Mogensen, U. M., Kragholm, K., Jhund, P. S., Petrie, M. C., Schou, M., Gislason, G. H., McMurray, J. J.V., Torp-Pedersen, C., Køber, L., Kristensen, S. L. (2018) Evidence based therapy and its association with workforce detachment following first hospitalization for heart failure. JACC: Heart Failure, 6, pp. 41-48. (doi: 10.1016/j.jchf.2017.09.019)

Bihlmeyer, N. A. et al. (2018) ExomeChip-wide analysis of 95 626 individuals identifies 10 novel loci associated with QT and JT intervals. Circulation: Genomic and Precision Medicine, 11, (doi: 10.1161/CIRCGEN.117.001758)

Beggs, S. A.S., Jhund, P. S., Jackson, C. E., McMurray, J. J.V., Gardner, R. S. (2018) Non-ischaemic cardiomyopathy, sudden death and implantable defibrillators: a review and meta-analysis. Heart, 104, pp. 144-150. (doi: 10.1136/heartjnl-2016-310850)

Burton, J. K., Ferguson, E. E.C., Barugh, A. J., Walesby, K. E., MacLullich, A. M.J., Shenkin, S. D., Quinn, T. J. (2018) Predicting discharge to institutional long-term care after stroke: a systematic review and metaanalysis. Journal of the American Geriatrics Society, 66, pp. 161-169. (doi: 10.1111/jgs.15101)

Turcot, V. et al. (2018) Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity. Nature Genetics, 50, pp. 26-41. (doi: 10.1038/s41588-017-0011-x)

Padmanabhan, S., Tan, L.-E., Dominiczak, A. F. (2018) Genetics of blood pressure and hypertension. Springer

McAllister, D. A., Read, S., Kerssens, J., Livingstone, S., McGurnaghan, S., Jhund, P., Petrie, J., Sattar, N., Fischbacher, C., Kristensen, S. L., McMurray, J., Colhoun, H. M., Wild, S. (2018) Incidence of hospitalisation for heart failure and case-fatality among 3.25 million people with and without diabetes. Circulation, 138, pp. 2774-2785. (doi: 10.1161/CIRCULATIONAHA.118.034986)

Rørth, R., Fosbøl, E. L., Kragholm, K., Mogensen, U. M., Jhund, P. S., Petrie, M. C., Torp-Pedersen, C., Gislason, G. H., McMurray, J. J.V., Køber, L., Kristensen, S. L. (2018) Initiation of domiciliary care and nursing home admission following first hospitalization for heart failure: a nationwide cohort study. Clinical Epidemiology, 10, pp. 917-930. (doi: 10.2147/CLEP.S164795)

2017

Todd, A., Blackley, S., Burton, J. K., Stott, D. J., Ely, E. W., Tieges, Z., MacLullich, A. M.J., Shenkin, S. D. (2017) Reduced level of arousal and increased mortality in adult acute medical admissions: a systematic review and meta-analysis. BMC Geriatrics, 17, (doi: 10.1186/s12877-017-0661-7)

Celis-Morales, C. A., Petermann, F., Hui, L., Lyall, D. M., Iliodromiti, S., McLaren, J., Anderson, J., Welsh, P., Mackay, D. F., Pell, J. P., Sattar, N., Gill, J. M.R., Gray, S. R. (2017) Associations between diabetes and both cardiovascular disease and all-cause mortality are modified by grip strength: evidence from UK Biobank, a prospective population-based cohort study. Diabetes Care, 40, pp. 1710-1718. (doi: 10.2337/dc17-0921)

Kaye, D. M., Silvestry, F. E., Gustafsson, F., Cleland, J. G., van Veldhuisen, D. J., Ponikowski, P., Komtebedde, J., Nanayakkara, S., Burkhoff, D., Shah, S. J. (2017) Impact of atrial fibrillation on rest and exercise haemodynamics in heart failure with mid-range and preserved ejection fraction. European Journal of Heart Failure, 19, pp. 1690-1697. (doi: 10.1002/ejhf.930)

Carberry, J., Carrick, D., Haig, C., Ahmed, N., Mordi, I., McEntegart, M., Petrie, M. C., Eteiba, H., Hood, S., Watkins, S., Lindsay, M., Davie, A., Mahrous, A., Ford, I., Sattar, N., Welsh, P., Radjenovic, A., Oldroyd, K. G., Berry, C. (2017) Persistence of infarct zone T2 hyperintensity at 6 months after acute ST-elevation myocardial infarction: incidence, pathophysiology and prognostic implications. Circulation: Cardiovascular Imaging, 10, (doi: 10.1161/CIRCIMAGING.117.006586)

Kristensen, S. L., Jhund, P. S., Lee, M. M.Y., Køber, L., Solomon, S. D., Granger, C. B., Yusuf, S., Pfeffer, M. A., Swedberg, K., McMurray, J. J.V. (2017) Prevalence of prediabetes and undiagnosed diabetes in patients with HFpEF and HFrEF and associated clinical outcomes. Cardiovascular Drugs and Therapy, 31, pp. 545-549. (doi: 10.1007/s10557-017-6754-x)

Vieira, M. C., White, S. L., Patel, N., Seed, P. T., Briley, A. L., Sandall, J., Welsh, P., Sattar, N., Nelson, S. M., Lawlor, D. A., Poston, L., Pasupathy, D. (2017) Prediction of uncomplicated pregnancies in obese women: a prospective multicentre study. BMC Medicine, 15, (doi: 10.1186/s12916-017-0956-8)

Sartini, C., Whincup, P. H., Wannamethee, S. G., Jefferis, B. J., Lennon, L., Lowe, G. D.O., Welsh, P., Sattar, N., Morris, R. W. (2017) Associations of time of day with cardiovascular disease risk factors measured in older men: results from the British Regional Heart Study. BMJ Open, 7, (doi: 10.1136/bmjopen-2017-018264)

MacDonald, T. M., Williams, B., Webb, D. J., Morant, S., Caulfield, M., Cruickshank, J. K., Ford, I., Sever, P., Mackenzie, I. S., Padmanabhan, S., McCann, G. P., Salsbury, J., McInnes, G., Brown, M. J. (2017) Combination therapy is superior to sequential monotherapy for the initial treatment of hypertension: a double-blind randomized controlled trial. Journal of the American Heart Association, 6, (doi: 10.1161/JAHA.117.006986)

Shen, L., Ramires, F., Martinez, F., Bodanese, L. C., Echeverría, L. E., Gómez, E. a., Abraham, W. t., Dickstein, K., Køber, L., Packer, M., Rouleau, J. L., Solomon, S. D., Swedberg, K., Zile, M. R., Jhund, P. S., Gimpelewicz, C. R., McMurray, J. J.V. (2017) Contemporary characteristics and outcomes in chagasic heart failure compared with other nonischemic and ischemic cardiomyopathy. Circulation: Heart Failure, 10, (doi: 10.1161/CIRCHEARTFAILURE.117.004361)

Holman, R. R., Coleman, R. L., Chan, J. C. N., Chiasson, J.-L., Feng, H., Ge, J., Gerstein, H. C., Gray, R., Huo, Y., Lang, Z., McMurray, J. J., Rydén, L., Schröder, S., Sun, Y., Theodorakis, M. J., Tendera, M., Tucker, L., Tuomilehto, J., Wei, Y., Yang, W., Wang, D., Hu, D., Pan, C., ACE Study Group, (2017) Effects of acarbose on cardiovascular and diabetes outcomes in patients with coronary heart disease and impaired glucose tolerance (ACE): a randomised, double-blind, placebo-controlled trial. Lancet Diabetes and Endocrinology, 5, pp. 877-886. (doi: 10.1016/S2213-8587(17)30309-1)

Wong, C. M., Hawkins, N. M., Ezekowitz, J. A., Jhund, P. S., Savu, A., MacDonald, M. R., Kristensen, S. L., Petrie, M. C., McMurray, J. J.V., McAlister, F. A., Kaul, P. (2017) Heart failure in young adults is associated with high mortality: a contemporary population-level analysis. Canadian Journal of Cardiology, 33, pp. 1472-1477. (doi: 10.1016/j.cjca.2017.05.009)

Welsh, P., Grassia, G., Botha, S., Sattar, N., Maffia, P. (2017) Targeting inflammation to reduce cardiovascular disease risk: a realistic clinical prospect? British Journal of Pharmacology, 174, pp. 3898-3913. (doi: 10.1111/bph.13818)

Mogensen, U. M., Jhund, P. S., Abraham, W. T., Desai, A. S., Dickstein, K., Packer, M., Rouleau, J. L., Solomon, S. D., Swedberg, K., Zile, M. R., Køber, L., McMurray, J. J.V. (2017) Type of atrial fibrillation and clinical outcomes in patients with heart failure and reduced ejection fraction. Journal of the American College of Cardiology, 70, pp. 2490-2500. (doi: 10.1016/j.jacc.2017.09.027)

Rutherford, E., Mangion, K., Mccomb, C., Bell, E., Cockburn, S., Talle, M., Roditi, G., Welsh, P., Woodward, R., Radjenovic, A., Struthers, A. D., Jardine, A., Berry, C., Patel, R. K., Mark, P. B. (2017) Myocardial changes in incident haemodialysis patients over 6-months: an observational cardiac magnetic resonance imaging study. Scientific Reports, 7, (doi: 10.1038/s41598-017-14481-y)

Bayes-Genis, A., Núñez, J., Zannad, F., Ferreira, J. P., Anker, S. D., Cleland, J. G., Dickstein, K., Filippatos, G., Lang, C. C., Ng, L. L., Ponikowski, P., Samani, N. J., van Veldhuisen, D. J., Zwinderman, A. H., Metra, M., Lupón, J., Voors, A. A. (2017) The PCSK9-LDL receptor axis and outcomes in heart failure: BIOSTAT-CHF subanalysis. Journal of the American College of Cardiology, 70, pp. 2128-2136. (doi: 10.1016/j.jacc.2017.08.057)

Sharma, A., Demissei, B. G., Tromp, J., Hillege, H. L., Cleland, J. G.F., O'Connor, C. M., Metra, M., Ponikowski, P., Teerlink, J. R., Davison, B. A., Givertz, M. M., Bloomfield, D. M., Dittrich, H., van Veldhuisen, D. J., Cotter, G., Ezekowitz, J. A., Khan, M. A.F., Voors, A. A. (2017) A network analysis to compare biomarker profiles in patients with and without diabetes mellitus in acute heart failure. European Journal of Heart Failure, 19, pp. 1310-1320. (doi: 10.1002/ejhf.912)

Clarke, T.-K., Adams, M.J., Davies, G., Howard, D.M., Hall, L.S., Padmanabhan, S., Murray, A.D., Smith, B.H., Campbell, A., Hayward, C., Porteous, D.J., Deary, I.J., McIntosh, A.M. (2017) Genome-wide association study of alcohol consumption and genetic overlap with other health-related traits in UK Biobank (N=112 117) Molecular Psychiatry, 22, pp. 1376-1384. (doi: 10.1038/mp.2017.153)

White, S. L., Pasupathy, D., Sattar, N., Nelson, S. M., Lawlor, D. A., Briley, A. L., Seed, P. T., Welsh, P., Poston, L. (2017) Metabolic profiling of gestational diabetes in obese women during pregnancy. Diabetologia, 60, pp. 1903-1912. (doi: 10.1007/s00125-017-4380-6)

Ferreira, J. P., Rossignol, P., Machu, J.-L., Sharma, A., Girerd, N., Anker, S. D., Cleland, J. G., Dickstein, K., Filippatos, G., Hillege, H. L., Lang, C. C., Ter Maaten, J., Metra, M., Ng, L., Ponikowski, P., Samani, N. J., van Veldhuisen, D. J., Zwinderman, A. H., Voors, A., Zannad, F. (2017) Mineralocorticoid receptor antagonist pattern of use in heart failure with reduced ejection fraction: findings from BIOSTAT-CHF. European Journal of Heart Failure, 19, pp. 1284-1293. (doi: 10.1002/ejhf.900)

Kraja, A. T. et al. (2017) New blood pressure–associated loci identified in meta-analyses of 475 000 individuals. Circulation: Cardiovascular Genetics, 10, (doi: 10.1161/CIRCGENETICS.117.001778)

Nassif, M. E., Tang, Y., Cleland, J. G.F., Abraham, W. T., Linde, C., Gold, M. R., Young, J. B., Daubert, J. C., Sherfesee, L., Schaber, D., Tang, A. S.L., Jones, P. G., Arnold, S. V., Spertus, J. A. (2017) Precision medicine for cardiac resynchronization: predicting quality of life benefits for individual patients-an analysis from 5 clinical trials. Circulation: Heart Failure, 10, (doi: 10.1161/CIRCHEARTFAILURE.117.004111)

Kristensen, S. L., Jhund, P. S., Mogensen, U. M., Rørth, R., Abraham, W. T., Desai, A., Dickstein, K., Rouleau, J. L., Zile, M. R., Swedberg, K., Packer, M., Solomon, S. D., Køber, L., McMurray, J. J.V. (2017) Prognostic value of N-terminal pro-B-type natriuretic peptide levels in heart failure patients with and without atrial fibrillation. Circulation: Heart Failure, 10, (doi: 10.1161/CIRCHEARTFAILURE.117.004409)

Padmanabhan, S., Joe, B. (2017) Towards precision medicine for hypertension: a review of genomic, epigenomic, and microbiomic effects on blood pressure in experimental rat models and humans. Physiological Reviews, 97, pp. 1469-1528. (doi: 10.1152/physrev.00035.2016)

Cleland, J. G.F., Halliday, B. P., Prasad, S. K. (2017) Selecting patients with nonischemic dilated cardiomyopathy for ICDs. Journal of the American College of Cardiology, 70, pp. 1228-1231. (doi: 10.1016/j.jacc.2017.07.748)

Zeng, Y. et al. (2017) Genome-wide regional heritability mapping identifies a locus within the TOX2 gene associated with major depressive disorder. Biological Psychiatry, 82, pp. 312-321. (doi: 10.1016/j.biopsych.2016.12.012)

Che Roos, N. A., Alsanosi, S. M., Alsieni, M. A., Gupta, M., Padmanabhan, S. (2017) Antihypertensive Drugs and Risk of Cancer: A Systematic Review and Meta-Analysis of 391, 790 Patients. (doi: 10.1161/hyp.70.suppl_1.p129)

Fröhlich, H., Torres, L., Täger, T., Schellberg, D., Corletto, A., Kazmi, S., Goode, K., Grundtvig, M., Hole, T., Katus, H. A., Cleland, J. G.F., Atar, D., Clark, A. L., Agewall, S., Frankenstein, L. (2017) Bisoprolol compared with carvedilol and metoprolol succinate in the treatment of patients with chronic heart failure. Clinical Research in Cardiology, 106, pp. 711-721. (doi: 10.1007/s00392-017-1115-0)

Wannamethee, S. G., Welsh, P., Papacosta, O., Ellins, E. A., Halcox, J. P.J., Whincup, P. H., Sattar, N. (2017) Circulating soluble receptor for advanced glycation end product: cross-sectional associations with cardiac markers and subclinical vascular disease in older men with and without diabetes. Atherosclerosis, 264, pp. 36-43. (doi: 10.1016/j.atherosclerosis.2017.07.008)

Price, A. H., Weir, C. J., Welsh, P., McLachlan, S., Strachan, M. W.J., Sattar, N., Price, J. F. (2017) Comparison of non-traditional biomarkers, and combinations of biomarkers, for vascular risk prediction in people with type 2 diabetes: The Edinburgh Type 2 Diabetes Study. Atherosclerosis, 264, pp. 67-73. (doi: 10.1016/j.atherosclerosis.2017.07.009)

Cleland, J. G.F. (2017) Does aspirin detract from the benefits of mineralocorticoid receptor antagonists in patients with heart failure and a reduced left ventricular ejection fraction? Probably! European Journal of Heart Failure, 19, pp. 1086-1088. (doi: 10.1002/ejhf.697)

Platz, E., Merz, A. A., Jhund, P. S., Vazir, A., Campbell, R., McMurray, J. J. (2017) Dynamic changes and prognostic value of pulmonary congestion by lung ultrasound in acute and chronic heart failure: a systematic review. European Journal of Heart Failure, 19, pp. 1154-1163. (doi: 10.1002/ejhf.839)

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Matsue, Y., ter Maaten, J. M., Struck, J., Metra, M., O'Connor, C. M., Ponikowski, P., Teerlink, J. R., Cotter, G., Davison, B., Cleland, J. G.F., Givertz, M. M., Bloomfield, D. M., Dittrich, H. C., van Veldhuisen, D. J., van der Meer, P., Damman, K., Voors, A. A. (2017) Clinical correlates and prognostic value of proenkephalin in acute and chronic heart failure. Journal of Cardiac Failure, 23, pp. 231-239. (doi: 10.1016/j.cardfail.2016.09.007)

Ali, M., MacIsaac, R., Quinn, T. J., Bath, P. M., Veenstra, D. L., Xu, Y., Brady, M. C., Patel, A., Lees, K. R. (2017) Dependency and health utilities in stroke: Data to inform cost-effectiveness analyses. European Stroke Journal, 2, pp. 70-76. (doi: 10.1177/2396987316683780)

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Parsons, T. J., Sartini, C., Welsh, P., Sattar, N., Ash, S., Lennon, L. T., Wannamethee, S. G., Lee, I.-M., Whincup, P. H., Jefferis, B. J. (2017) Physical activity, sedentary behavior, and inflammatory and hemostatic markers in men. Medicine and Science in Sports and Exercise, 49, pp. 459-465. (doi: 10.1249/MSS.0000000000001113)

Sartini, C., Barry, S. J.E., Whincup, P. H., Wannamethee, S. G., Lowe, G. D.O., Jefferis, B. J., Lennon, L., Welsh, P., Ford, I., Sattar, N., Morris, R. W. (2017) Relationship between outdoor temperature and cardiovascular disease risk factors in older people. European Journal of Preventive Cardiology, 24, pp. 349-356. (doi: 10.1177/2047487316682119)

Masters, J., Morton, G., Anton, I., Szymanski, J., Greenwood, E., Grogono, J., Flett, A. S., Cleland, J. G.F., Cowburn, P. J. (2017) Specialist intervention is associated with improved patient outcomes in patients with decompensated heart failure: evaluation of the impact of a multidisciplinary inpatient heart failure team. Open Heart, 4, (doi: 10.1136/openhrt-2016-000547)

Preiss, D., Dawed, A., Welsh, P., Heggie, A., Jones, A. G., Dekker, J., Koivula, R., Hansen, T. H., Stewart, C., Holman, R. R., Franks, P. W., Walker, M., Pearson, E. R., Sattar, N. (2017) Sustained influence of metformin therapy on circulating glucagon-like peptide-1 levels in individuals with and without type 2 diabetes. Diabetes, Obesity and Metabolism, 19, pp. 356-363. (doi: 10.1111/dom.12826)

Dierckx, R., Inglis, S. C., Clark, R. A., Prieto-Merino, D., Cleland, J. G.F. (2017) Telemedicine in heart failure: new insights from the Cochrane meta-analyses. European Journal of Heart Failure, 19, pp. 304-306. (doi: 10.1002/ejhf.759)

Carty, D. M., Doogan, F., Welsh, P., Dominiczak, A. F., Delles, C. (2017) Thyroid stimulating hormone (TSH) ≥2.5mU/l in early pregnancy: prevalence and subsequent outcomes. European Journal of Obstetrics and Gynecology and Reproductive Biology, 210, pp. 366-369. (doi: 10.1016/j.ejogrb.2017.01.048)

MacIsaac, R. L., Ali, M., Taylor-Rowan, M., Rodgers, H., Lees, K. R., Quinn, T. J. (2017) Use of a 3-item short-form version of the Barthel Index for use in stroke. Stroke, 48, pp. 618-623. (doi: 10.1161/STROKEAHA.116.014789)

van Hecke, O., Hocking, L. J., Torrance, N., Campbell, A., Padmanabhan, S., Porteous, D. J., McIntosh, A. M., Burri, A. V., Tanaka, H., Williams, F. M.K.>, Smith, B. H. (2017) Chronic pain, depression and cardiovascular disease linked through a shared genetic predisposition: Analysis of a family-based cohort and twin study. PLoS ONE, 12, (doi: 10.1371/journal.pone.0170653)

Zeng, Y., Navarro, P., Fernandez-Pujals, A. M., Hall, L. S., Clarke, T.-K., Thomson, P. A., Smith, B. H., Hocking, L. J., Padmanabhan, S., Hayward, C., MacIntyre, D. J., Wray, N. R., Deary, I. J., Porteous, D. J., Haley, C. S., McIntosh, A. M. (2017) A combined pathway and regional heritability analysis indicates NETRIN1 pathway is associated with major depressive disorder. Biological Psychiatry, 81, pp. 336-346. (doi: 10.1016/j.biopsych.2016.04.017)

Marouli, E. et al. (2017) Rare and low-frequency coding variants alter human adult height. Nature, 542, pp. 186-190. (doi: 10.1038/nature21039)

Docherty, K. F., Campbell, R. T., Jhund, P., Petrie, M. C., McMurray, J. J.V. (2017) How robust are clinical trials in heart failure? European Heart Journal, 38, pp. 338-345. (doi: 10.1093/eurheartj/ehw427)

Emdin, C. A., Hsiao, A. J., Kiran, A., Conrad, N., Salimi-Khorshidi, G., Woodward, M., Anderson, S. G., Mohseni, H., McMurray, J. J.V., Cleland, J. G.F., Dargie, H., Hardman, S., McDonagh, T., Rahimi, K. (2017) Referral for specialist follow-up and its association with post-discharge mortality among patients with systolic heart failure (from the National Heart Failure Audit for England and Wales) American Journal of Cardiology, 119, pp. 440-444. (doi: 10.1016/j.amjcard.2016.10.021)

Arba, F., Quinn, T., Hankey, G.J., Ali, M., Lees, K. R., Inzitari, D. (2017) Cerebral small vessel disease, medial temporal lobe atrophy and cognitive status in patients with ischaemic stroke and transient ischaemic attack. European Journal of Neurology, 24, pp. 276-282. (doi: 10.1111/ene.13191)

Schmidt, A. F. et al. (2017) PCSK9 genetic variants and risk of type 2 diabetes: a mendelian randomisation study. Lancet Diabetes and Endocrinology, 5, pp. 97-105. (doi: 10.1016/S2213-8587(16)30396-5)

Gastelurrutia, P., Lupón, J., Domingo, M., Stut, W., Dovancescu, S., Cleland, J., Frankenstein, L., Bayes-Genis, A. (2017) Potential role for clinical calibration to increase engagement with and application of home telemonitoring: a report from the HeartCycle programme. ESC Heart Failure, 4, pp. 66-70. (doi: 10.1002/ehf2.12104)

Zhang, J., Dierckx, R., Mohee, K., Clark, A. L., Cleland, J. G.F. (2017) Xanthine oxidase inhibition for the treatment of cardiovascular disease: an updated systematic review and meta-analysis. ESC Heart Failure, 4, pp. 40-45. (doi: 10.1002/ehf2.12112)

Schulz, C., Padmanabhan, S. (2017) Methods to assess genetic risk prediction. Springer

Tsiropoulou, S., McBride, M., Padmanabhan, S. (2017) Urine metabolomics in hypertension research. Springer

Jeemon, P., Harikrishnan, S., Sanjay, G., Sivasubramonian, S., Lekha, T.R., Padmanabhan, S., Tandon, N., Prabhakaran, D. (2017) A PROgramme of Lifestyle Intervention in Families for Cardiovascular risk reduction (PROLIFIC Study): design and rationale of a family based randomized controlled trial in individuals with family history of premature coronary heart disease. BMC Public Health, 17, (doi: 10.1186/s12889-016-3928-6)

Cannon, J. A., Shen, L., Jhund, P. S., Kristensen, S. L., Køber, L., Chen, F., Gong, J., Lefkowitz, M. P., Rouleau, J. L., Shi, V. C., Swedberg, K., Zile, M. R., Solomon, S. D., Packer, M., McMurray, J. J.V. (2017) Dementia-related adverse events in PARADIGM-HF and other trials in heart failure with reduced ejection fraction. European Journal of Heart Failure, 19, pp. 129-137. (doi: 10.1002/ejhf.687)

Streng, K. W., ter Maaten, J. M., Cleland, J. G.F., O’Connor, C. M., Davison, B. A., Metra, M., Givertz, M. M., Teerlink, J. R., Ponikowski, P., Bloomfield, D. M., Dittrich, H. C., Hillege, H. L., van Veldhuisen, D. J., Voors, A. A., van der Meer, P. (2017) Associations of body mass index with laboratory and biomarkers in patients with acute heart failure. Circulation: Heart Failure, 10, (doi: 10.1161/CIRCHEARTFAILURE.116.003350)

Kristensen, S. L., Mogensen, U. M., Jhund, P. S., Petrie, M. C., Preiss, D., Win, S., Køber, L., McKelvie, R. S., Zile, M. R., Anand, I. S., Komajda, M., Gottdiener, J. S., Carson, P. E., McMurray, J. J.V. (2017) Clinical and echocardiographic characteristics and cardiovascular outcomes according to diabetes status in patients with heart failure and preserved ejection fraction. A report from the Irbesartan in Heart Failure with Preserved Ejection Fraction Trial (I-Preserve) Circulation, 135, pp. 724-735. (doi: 10.1161/CIRCULATIONAHA.116.024593)

Salvi, E. et al. (2017) Genome-wide and gene-based meta-analyses identify novel loci influencing blood pressure response to hydrochlorothiazide. Hypertension, 69, pp. 51-59. (doi: 10.1161/HYPERTENSIONAHA.116.08267)

Tromp, J., ter Maaten, J., Damman, K., O’Connor, C. M., Metra, M., Dittrich, H. C., Ponikowski, P., Teerlink, J. R., Cotter, G., Davison, B., Cleland, J. G.F., Givertz, M. M., Bloomfield, D. M., van der Wal, M. H.L., Jaarsma, T., van Veldhuisen, D. J., Hillege, H. L., Voors, A. A., van der Meer, P. (2017) Serum potassium levels and outcome in acute heart failure (data from the PROTECT and COACH trials) American Journal of Cardiology, 119, pp. 290-296. (doi: 10.1016/j.amjcard.2016.09.038)

Cameron, A. C., Lang, N. N., Touyz, R. M. (2017) Cardiovascular complications from cancer therapy: hypertension-focus on vascular endothelial growth factor inhibitors. Elesvier

Ridker, P. M. et al. (2017) Cardiovascular efficacy and safety of Bococizumab in high-risk patients. New England Journal of Medicine, 376, pp. 1527-1539. (doi: 10.1056/NEJMoa1701488)

Celis-Morales, C., Lyall, D. M., Gray, S., Steell, L., Anderson, J., Iliodromiti, S., Welsh, P., Guo, Y., Petermann, F., Mackay, D. F., Bailey, M. E.S., Pell, J., Gill, J. M.R., Sattar, N. (2017) Dietary fat and total energy intake modifies the association of genetic profile risk score on obesity: evidence from 48 170 UK Biobank participants. International Journal of Obesity, 41, pp. 1761-1768. (doi: 10.1038/ijo.2017.169)

Liu, D. J. et al. (2017) Exome-wide association study of plasma lipids in >300,000 individuals. Nature Genetics, 49, pp. 1758-1766. (doi: 10.1038/ng.3977)

Power, R. A. et al. (2017) Genome-wide association for major depression through age at onset stratification: major depressive disorder working group of the psychiatric genomics consortium. Biological Psychiatry, 81, pp. 325-335. (doi: 10.1016/j.biopsych.2016.05.010)

Burton, J.K., Quinn, T.J., Gordon, A.L., MacLullich, A.M.J., Reynish, E.L., Shenkin, S.D. (2017) Identifying published studies of care home research: an international survey of researchers. Journal of Nursing Home Research, 3, pp. 99-102. (doi: 10.14283/jnhrs.2017.15)

Arain, F., Gullestad, L., Nymo, S., Kjekshus, J., Cleland, J. G.F., Michelsen, A., McMurray, J. J.V., Wikstrand, J., Aukrust, P., Ueland, T. (2017) Low YKL-40 in Chronic Heart Failure may predict beneficial effects of statins: Analysis from the Controlled Rosuvastatin Multinational Trial in Heart Failure (CORONA) Biomarkers, 22, pp. 261-267. (doi: 10.1080/1354750X.2016.1204003)

2016

Torabi, A., Cleland, J. G.F., Sherwi, N., Atkin, P., Panahi, H., Kilpatrick, E., Thackray, S., Hoye, A., Alamgir, F., Goode, K., Rigby, A., Clark, A. L. (2016) Influence of case definition on incidence and outcome of acute coronary syndromes. Open Heart, 3, (doi: 10.1136/openhrt-2016-000487)

Teerlink, J. R., Felker, G. M., McMurray, J. J.V., Solomon, S. D., Adams, Jr., K. F., Cleland, J. G.F., Ezekowitz, J. A., Goudev, A., Macdonald, P., Metra, M., Mitrovic, V., Ponikowski, P., Serpytis, P., Spinar, J., Tomcsányi, J., Vandekerckhove, H. J., Voors, A. A., Monsalvo, M. L., Johnston, J., Malik, F. I., Honarpour, N. (2016) Chronic oral study of myosin activation to increase contractility in heart failure (COSMIC-HF): a phase 2, pharmacokinetic, randomised, placebo-controlled trial. Lancet, 388, pp. 2895-2903. (doi: 10.1016/S0140-6736(16)32049-9)

White, S. L., Lawlor, D. A., Briley, A. L., Godfrey, K. M., Nelson, S. M., Oteng-Ntim, E., Robson, S. C., Sattar, N., Seed, P. T., Vieira, M. C., Welsh, P., Whitworth, M., Poston, L., Pasupathy, D. (2016) Early antenatal prediction of gestational diabetes in obese women: development of prediction tools for targeted intervention. PLoS ONE, 11, (doi: 10.1371/journal.pone.0167846)

Vegter, E. L., Schmitter, D., Hagemeijer, Y., Ovchinnikova, E. S., van der Harst, P., Teerlink, J. R., O'Connor, C. M., Metra, M., Davison, B. A., Bloomfield, D., Cotter, G., Cleland, J. G.F., Givertz, M. M., Ponikowski, P., van Veldhuisen, D. J., van der Meer, P., Berezikov, E., Voors, A. A., Khan, M. A.F. (2016) Use of biomarkers to establish potential role and function of circulating microRNAs in acute heart failure. International Journal of Cardiology, 224, pp. 231-239. (doi: 10.1016/j.ijcard.2016.09.010)

Pellicori, P., Cleland, J. G.F., Zhang, J., Kallvikbacka-Bennett, A., Urbinati, A., Shah, P., Kazmi, S., Clark, A. L. (2016) Cardiac dysfunction, congestion and loop diuretics: their relationship to prognosis in heart failure. Cardiovascular Drugs and Therapy, 30, pp. 599-609. (doi: 10.1007/s10557-016-6697-7)

Zeng, Y., Navarro, P., Xia, C., Amador, C., Fernandez-Pujals, A. M., Thomson, P. A., Campbell, A., Nagy, R., Clarke, T.-K., Hafferty, J. D., Smith, B. H., Hocking, L. J., Padmanabhan, S., Hayward, C., MacIntyre, D. J., Porteous, D. J., Haley, C. S., McIntosh, A. M. (2016) Shared genetics and couple-associated environment are major contributors to the risk of both clinical and self-declared depression. EBioMedicine, 14, pp. 161-167. (doi: 10.1016/j.ebiom.2016.11.003)

Harrison, J. K., Stott, D. J., McShane, R., Noel-Storr, A. H., Swann-Price, R. S., Quinn, T. J. (2016) Informant questionnaire on cognitive decline in the elderly (IQCODE) for the early diagnosis of dementia across a variety of healthcare settings. Cochrane Database of Systematic Reviews, 2016, (doi: 10.1002/14651858.cd011333.pub2)

Harrison, J. K., Noel-Storr, A. H., Demeyere, N., Reynish, E. L., Quinn, T. J. (2016) Outcomes measures in a decade of dementia and mild cognitive impairment trials. Alzheimer's Research and Therapy, 8, (doi: 10.1186/s13195-016-0216-8)

Inglis, S. C., Clark, R. A., Dierckx, R., Prieto-Merino, D., Cleland, J. G.F. (2016) Structured telephone support or non-invasive telemonitoring for patients with heart failure. Heart, 103, pp. 255-257. (doi: 10.1136/heartjnl-2015-309191)

Demissei, B. G., Postmus, D., Liu, L. C.Y., Cleland, J. G.F., O'Connor, C. M., Metra, M., Ponikowski, P., Teerlink, J. R., Cotter, G., Davison, B. A., Edwards, C., Givertz, M. M., Bloomfield, D. M., Dittrich, H. C., Voors, A. A., Hillege, H. L. (2016) Risk-based evaluation of efficacy of rolofylline in patients hospitalized with acute heart failure — Post-hoc analysis of the PROTECT trial. International Journal of Cardiology, 223, pp. 967-975. (doi: 10.1016/j.ijcard.2016.08.271)

Ferreira, J. P., Girerd, N., Pellicori, P., Duarte, K., Girerd, S., Pfeffer, M. A., McMurray, J. J.V., Pitt, B., Dickstein, K., Jacobs, L., Staessen, J. A., Butler, J., Latini, R., Masson, S., Mebazaa, A., Rocca, H. P. B.-L., Delles, C., Heymans, S., Sattar, N., Jukema, J. W., Cleland, J. G.F., Zannad, F., Rossignol, P. (2016) Renal function estimation and Cockroft–Gault formulas for predicting cardiovascular mortality in population-based, cardiovascular risk, heart failure and post-myocardial infarction cohorts: the Heart ‘OMics’ in AGEing (HOMAGE) and the high-risk myocardial infarction database initiatives. BMC Medicine, 14, (doi: 10.1186/s12916-016-0731-2)

Jhund, P. S. (2016) Geographic variation in heart failure - a matter of celebration or condemnation? European Journal of Heart Failure, 18, pp. 1329-1330. (doi: 10.1002/ejhf.652)

Harrison, J. K., Van Der Wardt, V., Conroy, S. P., Stott, D. J., Dening, T., Gordon, A. L., Logan, P., Welsh, T. J., Taggar, J., Harwood, R., Gladman, J. R.F. (2016) New horizons: the management of hypertension in people with dementia. Age and Ageing, 45, pp. 740-746. (doi: 10.1093/ageing/afw155)

Jongstra, S., Harrison, J. K., Quinn, T. J., Richard, E. (2016) Antihypertensive withdrawal for the prevention of cognitive decline. Cochrane Database of Systematic Reviews, 2016, (doi: 10.1002/14651858.cd011971.pub2)

Bekfani, T., Pellicori, P., Morris, D. A., Ebner, N., Valentova, M., Steinbeck, L., Wachter, R., Elsner, S., Sliziuk, V., Schefold, J. C., Sandek, A., Doehner, W., Cleland, J. G.F., Lainscak, M., Anker, S. D., von Haehling, S. (2016) Sarcopenia in patients with heart failure with preserved ejection fraction: impact on muscle strength, exercise capacity and quality of life. International Journal of Cardiology, 222, pp. 41-46. (doi: 10.1016/j.ijcard.2016.07.135)

Petrie, M. C., Jhund, P. S., She, L., Adlbrecht, C., Doenst, T., Panza, J. A., Hill, J. A., Lee, K. L., Rouleau, J. L., Prior, D. L., Ali, I. S., Maddury, J., Golba, K. S., White, H. D., Carson, P., Chrzanowski, L., Romanov, A., Miller, A. B., Velazquez, E. J. (2016) Ten-year outcomes after coronary artery bypass grafting according to age in patients with heart failure and left ventricular systolic dysfunction: an analysis of the extended follow-up of the STICH Trial (Surgical Treatment for Ischemic Heart Failure) Circulation, 134, pp. 1314-1324. (doi: 10.1161/CIRCULATIONAHA.116.024800)

Desai, A. S., Jhund, P. S. (2016) After TOPCAT: what to do now in heart failure with preserved ejection fraction. European Heart Journal, 37, pp. 3135-3140. (doi: 10.1093/eurheartj/ehw114)

Welsh, P., Tuckwell, K., McInnes, I. B., Sattar, N. (2016) Effect of IL-6 receptor blockade on high-sensitivity troponin T and NT-proBNP in rheumatoid arthritis. Atherosclerosis, 254, pp. 167-171. (doi: 10.1016/j.atherosclerosis.2016.10.016)

Preiss, D., Rankin, N., Welsh, P., Holman, R.R., Kangas, A.J., Soininen, P., Würtz, P., Ala-Korpela, M., Sattar, N. (2016) Effect of metformin therapy on circulating amino acids in a randomized trial: the CAMERA study. Diabetic Medicine, 33, pp. 1569-1574. (doi: 10.1111/dme.13097)

Gillespie, J., Beverland, I. J., Hamilton, S., Padmanabhan, S. (2016) Development, evaluation, and comparison of land use regression modeling methods to estimate residential exposure to nitrogen dioxide in a cohort study. Environmental Science and Technology, 50, pp. 11085-11093. (doi: 10.1021/acs.est.6b02089)

Tromp, J., Meyer, S., Mentz, R. J., O'Connor, C. M., Metra, M., Dittrich, H. C., Ponikowski, P., Teerlink, J. R., Cotter, G., Davison, B., Cleland, J. G.F., Givertz, M. M., Bloomfield, D. M., van Veldhuisen, D. J., Hillege, H. L., Voors, A. A., van der Meer, P. (2016) Acute heart failure in the young: clinical characteristics and biomarker profiles. International Journal of Cardiology, 221, pp. 1067-1072. (doi: 10.1016/j.ijcard.2016.06.339)

Boal, A. H., Smith, D. J., Mccallum, L., Muir, S., Touyz, R. M., Dominiczak, A. F., Padmanabhan, S. (2016) Monotherapy with major antihypertensive drug classes and risk of hospital admissions for mood disorders. Hypertension, 68, pp. 1132-1138. (doi: 10.1161/HYPERTENSIONAHA.116.08188)

Rørth, R., Wong, C., Kragholm, K., Fosbøl, E. L., Mogensen, U. M., Lamberts, M., Petrie, M. C., Jhund, P. S., Gerds, T. A., Torp-Pedersen, C., Gislason, G. H., McMurray, J. J.V., Køber, L., Kristensen, S. L. (2016) Return to the workforce following first hospitalization for heart failure: a Danish nationwide cohort study. Circulation, 134, pp. 999-1009. (doi: 10.1161/CIRCULATIONAHA.116.021859)

Sokoreli, I., de Vries, J.J.G., Riistama, J.M., Pauws, S.C., Steyerberg, E.W., Tesanovic, A., Geleijnse, G., Goode, K.M., Crundall-Goode, A., Kazmi, S., Cleland, J.G.F., Clark, A.L. (2016) Depression as an independent prognostic factor for all-cause mortality after a hospital admission for worsening heart failure. International Journal of Cardiology, 220, pp. 202-207. (doi: 10.1016/j.ijcard.2016.06.068)

Rutherford, E., Talle, M. A., Mangion, K., Bell, E., Rauhalammi, S. M., Roditi, G., McComb, C., Radjenovic, A., Welsh, P., Woodward, R., Struthers, A. D., Jardine, A. G., Patel, R. K., Berry, C., Mark, P. B. (2016) Definition of myocardial tissue abnormalities in end stage renal failure with cardiac magnetic resonance imaging using T1 mapping. Kidney International, 90, pp. 845-852. (doi: 10.1016/j.kint.2016.06.014)

Cameron, A. C., Lang, N. N., Touyz, R. M. (2016) Drug treatment of hypertension: focus on vascular health. Drugs, 76, pp. 1529-1550. (doi: 10.1007/s40265-016-0642-8)

Willeit, P. et al. (2016) Natriuretic peptides and integrated risk assessment for cardiovascular disease: an individual-participant-data meta-analysis. Lancet Diabetes and Endocrinology, 4, pp. 840-849. (doi: 10.1016/S2213-8587(16)30196-6)

Cleland, J. G.F., Pellicori, P. (2016) PARADIGM-HF: does dose matter? European Journal of Heart Failure, 18, pp. 1235-1237. (doi: 10.1002/ejhf.634)

Cotter, G., Davison, B. A., Milo, O., Bourge, R. C., Cleland, J. G.F., Jondeau, G., Krum, H., O'Connor, C. M., Metra, M., Parker, J. D., Torre-Amione, G., van Veldhuisen, D. J., Kobrin, I., Rainisio, M., Senger, S., Edwards, C., McMurray, J. J.V., Teerlink, J. R. (2016) Predictors and associations with outcomes of length of hospital stay in patients with acute heart failure: results from VERITAS. Journal of Cardiac Failure, 22, pp. 815-822. (doi: 10.1016/j.cardfail.2015.12.017)

Surendran, P. et al. (2016) Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension. Nature Genetics, 48, pp. 1151-1161. (doi: 10.1038/ng.3654)

van der Harst, P. et al. (2016) 52 genetic loci influencing myocardial mass. Journal of the American College of Cardiology, 68, pp. 1435-1448. (doi: 10.1016/j.jacc.2016.07.729)

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Welsh, P., Hart, C., Papacosta, O., Preiss, D., McConnachie, A., Murray, H., Ramsay, S., Upton, M., Watt, G., Whincup, P., Wannamethee, G., Sattar, N. (2016) Prediction of cardiovascular disease risk by cardiac biomarkers in 2 United Kingdom cohort studies: does utility depend on risk thresholds for treatment? Hypertension, 2016, pp. 309-315. (doi: 10.1161/HYPERTENSIONAHA.115.06501)

Johnson, M. R. et al. (2016) Systems genetics identifies a convergent gene network for cognition and neurodevelopmental disease. Nature Neuroscience, 19, pp. 223-232. (doi: 10.1038/nn.4205)

Carrick, D., Haig, C., Rauhalammi, S., Clerfond, G., Ahmed, N., Mordi, I., McEntegart, M., Petrie, M., Eteiba, H., Hood, S., Watkins, S., Lindsay, M. M., Mahrous, A., Welsh, P., Sattar, N., Ford, I., Oldroyd, K., Radjenovic, A., Berry, C. (2016) Temporal evolution of myocardial hemorrhage and edema in patients after acute ST-elevation myocardial infarction: pathophysiologic insights and clinical implications. Journal of the American Heart Association, 5, (doi: 10.1161/JAHA.115.002834)

Rankinen, T. et al. (2016) No evidence of a common DNA variant profile specific to world class endurance athletes. PLoS ONE, 11, (doi: 10.1371/journal.pone.0147330)

Bruno, N., ter Maaten, J. M., Ovchinnikova, E. S., Vegter, E. L., Valente, M. A.E., van der Meer, P., de Boer, R. A., van der Harst, P., Schmitter, D., Metra, M., O'Connor, C. M., Ponikowski, P., Teerlink, J. R., Cotter, G., Davison, B., Cleland, J. G.F., Givertz, M. M., Bloomfield, D. M., Dittrich, H. C., Pinto, Y. M., van Veldhuisen, D. J., Hillege, H. L., Berezikov, E., Voors, A. A. (2016) MicroRNAs relate to early worsening of renal function in patients with acute heart failure. International Journal of Cardiology, 203, pp. 564-569. (doi: 10.1016/j.ijcard.2015.10.217)

Zhang, J., Hobkirk, J., Carroll, S., Pellicori, P., Clark, A. L., Cleland, J. G.F. (2016) Exploring quality of life in patients with and without heart failure. International Journal of Cardiology, 202, pp. 676-684. (doi: 10.1016/j.ijcard.2015.09.076)

Zile, M. R., Jhund, P., Baicu, C. F., Claggett, B. L., Pieske, B., Voors, A. A., Prescott, M. F., Shi, V., Lefkowitz, M., McMurray, J., Solomon, S. D. (2016) Plasma biomarkers reflecting profibrotic processes in heart failure with a preserved ejection fraction. Circulation: Heart Failure, 9, (doi: 10.1161/circheartfailure.115.002551)

Kristensen, S. L., Preiss, D., Jhund, P. S., Squire, I., Cardoso, J. S., Merkely, B., Martinez, F., Starling, R. C., Desai, A. S., Lefkowitz, M. P., Rizkala, A. R., Rouleau, J. L., Shi, V. C., Solomon, S. D., Swedberg, K., Zile, M. R., McMurray, J. J.V., Packer, M. (2016) Risk related to pre–diabetes mellitus and diabetes mellitus in heart failure with reduced ejection fraction: insights from prospective comparison of ARNI with ACEI to determine impact on global mortality and morbidity in heart failure trial. Circulation: Heart Failure, 9, (doi: 10.1161/CIRCHEARTFAILURE.115.002560)

Jenkins, P., Sng, S., Brooksbank, K., Brooksbank, A.J. (2016) Socioeconomic deprivation and age are barriers to the online collection of patient reported outcome measures in orthopaedic patients. Annals of the Royal College of Surgeons of England, 98, pp. 40-44. (doi: 10.1308/rcsann.2016.0007)

Cowie, M. R., Bax, J., Bruining, N., Cleland, J. G.F., Koehler, F., Malik, M., Pinto, F., van der Velde, E., Vardas, P. (2016) e-Health: a position statement of the European Society of Cardiology. European Heart Journal, 37, pp. 63-66. (doi: 10.1093/eurheartj/ehv416)

Ponikowski, P., Voors, A. A., Anker, S. D., Bueno, H., Cleland, J. G.F., Coats, A. J.S., Falk, V., González-Juanatey, J. R., Harjola, V.-P., Jankowska, E. A., Jessup, M., Linde, C., Nihoyannopoulos, P., Parissis, J. T., Pieske, B., Riley, J. P., Rosano, G. M.C., Ruilope, L. M., Ruschitzka, F., Rutten, F. H., van der Meer, P., McMurray, J. J.V., Petrie, M. C. (2016) 2016 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure. European Heart Journal, 37, pp. 2129-2200. (doi: 10.1093/eurheartj/ehw128)

Nuesch, E. et al. (2016) Adult height, coronary heart disease and stroke: a multi-locus Mendelian randomization meta-analysis. International Journal of Epidemiology, 45, pp. 1927-1937. (doi: 10.1093/ije/dyv074)

Rankin, N. J., Preiss, D., Welsh, P., Sattar, N. (2016) Applying metabolomics to cardiometabolic intervention studies and trials: past experiences and a roadmap for the future. International Journal of Epidemiology, 45, pp. 1351-1371. (doi: 10.1093/ije/dyw271)

Platz, E., Lewis, E. F., Uno, H., Peck, J., Pivetta, E., Merz, A. A., Hempel, D., Wilson, C., Frasure, S. E., Jhund, P. S., Cheng, S., Solomon, S. D. (2016) Detection and prognostic value of pulmonary congestion by lung ultrasound in ambulatory heart failure patients. European Heart Journal, 37, pp. 1244-1251. (doi: 10.1093/eurheartj/ehv745)

Kristensen, S. L. et al. (2016) Geographic variations in the PARADIGM-HF heart failure trial. European Heart Journal, 37, pp. 3167-3174. (doi: 10.1093/eurheartj/ehw226)

Carrick, D., Haig, C., Watkins, S., Ahmed, N., McEntegart, M., Petrie, M. C., Eteiba, H., Hood, S., Watkins, S., Lindsay, M. M., Davie, A., Mahrous, A., Mordi, I., Rauhalammi, S., Sattar, N., Welsh, P., Radjenovic, A., Ford, I., Oldroyd, K., Berry, C. (2016) Myocardial hemorrhage after acute reperfused ST-segment-elevation myocardial infarction. Circulation: Cardiovascular Imaging, 9, (doi: 10.1161/CIRCIMAGING.115.004148)

Jackson, C. E., Haig, C., Welsh, P., Dalzell, J. R., Tsorlalis, I. K., McConnachie, A., Preiss, D., Anker, S. D., Sattar, N., Petrie, M. C., Gardner, R. S., McMurray, J. J. V. (2016) The incremental prognostic and clinical value of multiple novel biomarkers in heart failure. European Journal of Heart Failure, 18, pp. 1491-1498. (doi: 10.1002/ejhf.543)

Emdin, C. A., Conrad, N., Kiran, A., Salimi-Khorshidi, G., Woodward, M., Anderson, S. G., Mohseni, H., Dargie, H. J., Hardman, S. M.C., McDonagh, T., McMurray, J. J.V., Cleland, J. G.F., Rahimi, K. (2016) Variation in hospital performance for heart failure management in the National Heart Failure Audit for England and Wales. Heart, 103, pp. 55-62. (doi: 10.1136/heartjnl-2016-309706)

2015

Cameron, A. C., Touyz, R. M., Lang, N. N. (2015) Vascular complications of cancer chemotherapy. Canadian Journal of Cardiology, 32, pp. 852-862. (doi: 10.1016/j.cjca.2015.12.023)

Cleland, J. G.F., Mareev, Y. (2015) CRT for heart failure and ESRD: more trials or more thought needed? Journal of the American College of Cardiology, 66, pp. 2630-2632. (doi: 10.1016/j.jacc.2015.10.022)

Solbu, M. D., Thomson, P. C., Macpherson, S., Findlay, M. D., Stevens, K. K., Patel, R. K., Padmanabhan, S., Jardine, A. G., Mark, P. B. (2015) Serum phosphate and social deprivation independently predict all-cause mortality in chronic kidney disease. BMC Nephrology, 16, (doi: 10.1186/s12882-015-0187-1)

Linneberg, A. et al. (2015) Effect of smoking on blood pressure and resting heart rate: a Mendelian randomization meta-analysis in the CARTA Consortium. Circulation: Cardiovascular Genetics, 8, pp. 832-841. (doi: 10.1161/circgenetics.115.001225)

Day, F. R. et al. (2015) Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility, and BRCA1-mediated DNA repair [editorial comment] Obstetrical and Gynecological Survey, 70, pp. 758-762. (doi: 10.1097/01.ogx.0000473766.71624.99)

Artigas, M. S. et al. (2015) Sixteen new lung function signals identified through 1000 Genomes Project reference panel imputation. Nature Communications, 6, (doi: 10.1038/ncomms9658)

Williams, B., MacDonald, T. M., Morant, S., Webb, D. J., Sever, P., McInnes, G., Ford, I., Cruickshank, J. K., Caulfield, M. J., Salsbury, J., Mackenzie, I., Padmanabhan, S., Brown, M. J. (2015) Spironolactone versus placebo, bisoprolol, and doxazosin to determine the optimal treatment for drug-resistant hypertension (PATHWAY-2): a randomised, double-blind, crossover trial. Lancet, 386, pp. 2059-2068. (doi: 10.1016/S0140-6736(15)00257-3)

van Leeuwen, E. M. et al. (2015) Fine mapping the CETP region reveals a common intronic insertion associated to HDL-C. npj Aging and Mechanisms of Disease, 1, (doi: 10.1038/npjamd.2015.11)

Simpson, J., Jhund, P. S., Silva Cardoso, J., Martinez, F., Mosterd, A., Ramires, F., Rizkala, A. R., Senni, M., Squire, I., Gong, J., Lefkowitz, M. P., Shi, V. C., Desai, A. S., Rouleau, J. L., Swedberg, K., Zile, M. R., McMurray, J. J.V., Packer, M., Solomon, S. D. (2015) Comparing LCZ696 with Enalapril according to baseline risk using the MAGGIC and EMPHASIS-HF risk scores. Journal of the American College of Cardiology, 66, pp. 2059-2071. (doi: 10.1016/j.jacc.2015.08.878)

Jolicœur, E. M., Dunning, A., Castelvecchio, S., Dabrowski, R., Waclawiw, M. A., Petrie, M. C., Stewart, R., Jhund, P. S., Desvigne-Nickens, P., Panza, J. A., Bonow, R. O., Sun, B., San, T. R., Al-Khalidi, H. R., Rouleau, J. L., Velazquez, E. J., Cleland, J. G.F. (2015) Importance of angina in patients with coronary disease, heart failure, and left ventricular systolic dysfunction. Journal of the American College of Cardiology, 66, pp. 2092-2100. (doi: 10.1016/j.jacc.2015.08.882)

Cameron, A. C., Mccallum, L., Gardiner, T., Darroch, C., Walters, M. R., Oldroyd, K. G. (2015) Impact of treatment algorithms on the prescribing of antithrombotic therapy in patients with suspected acute coronary syndrome - a prospective audit. British Journal of Clinical Pharmacology, 80, pp. 1176-1184. (doi: 10.1111/bcp.12714)

Day, F. R. et al. (2015) Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair. Nature Genetics, 47, pp. 1294-1303. (doi: 10.1038/ng.3412)

Gong, Y., McDonough, C. W., Beitelshees, A. L., Rouby, N. E., Hiltunen, T. P., O’Connell, J. R., Padmanabhan, S., Langaee, T. Y., Hall, K., Schmidt, S. O.F., Curry, R. W., Gums, J. G., Donner, K. M., Kontula, K. K., Bailey, K. R., Boerwinkle, E., Takahashi, A., Tanaka, T., Kubo, M., Chapman, A. B., Turner, S. T., Pepine, C. J., Cooper-DeHoff, R. M., Johnson, J. A. (2015) PTPRD gene associated with blood pressure response to atenolol and resistant hypertension. Journal of Hypertension, 33, pp. 2278-2285. (doi: 10.1097/hjh.0000000000000714)

Pellicori, P., Joseph, A. C., Zhang, J., Lukaschuk, E., Sherwi, N., Bourantas, C. V., Loh, H., Clark, A. L., Cleland, J. G.F. (2015) The relationship of QRS morphology with cardiac structure and function in patients with heart failure. Clinical Research in Cardiology, 104, pp. 935-945. (doi: 10.1007/s00392-015-0861-0)

Inglis, S. C., Clark, R. A., Dierckx, R., Prieto-Merino, D., Cleland, J. G.F. (2015) Structured telephone support or non-invasive telemonitoring for patients with heart failure. Cochrane Database of Systematic Reviews, 2015, (doi: 10.1002/14651858.CD007228.pub3)

Jhund, P., Fu, M., Bayram, E., Chen, C.-H., Negrusz-Kawecka, M., Rosenthal, A., Desai, A. S., Lefkowitz, M. P., Rizkala, A. R., Rouleau, J. L., Shi, V. C., Solomon, S. D., Swedberg, K., Zile, M. R., McMurray, J. J.V., Packer, M. (2015) Efficacy and safety of LCZ696 (sacubitril-valsartan) according to age: insights from PARADIGM-HF. European Heart Journal, 36, pp. 2576-2584. (doi: 10.1093/eurheartj/ehv330)

Farag, M., Mabote, T., Shoaib, A., Zhang, J., Nabhan, A. F., Clark, A. L., Cleland, J. G. (2015) Hydralazine and nitrates alone or combined for the management of chronic heart failure: a systematic review. International Journal of Cardiology, 196, pp. 61-69. (doi: 10.1016/j.ijcard.2015.05.160)

Mareev, Y., Cleland, J. G.F. (2015) Should β-blockers be used in patients with heart failure and atrial fibrillation? Clinical Therapeutics, 37, pp. 2215-2224. (doi: 10.1016/j.clinthera.2015.08.017)

Shadman, R., Poole, J. E., Dardas, T. F., Mozaffarian, D., Cleland, J. G.F., Swedberg, K., Maggioni, A. P., Anand, I. S., Carson, P. E., Miller, A. B., Levy, W. C. (2015) A novel method to predict the proportional risk of sudden cardiac death in heart failure: derivation of the Seattle Proportional Risk Model. Heart Rhythm, 12, pp. 2069-2077. (doi: 10.1016/j.hrthm.2015.06.039)

Patel, R., Jeemon, P., Stevens, K., Mccallum, L., Hastie, C., Schneider, A., Jardine, A., Mark, P., Padmanabhan, S. (2015) Association between serum phosphate and calcium, long-term blood pressure, and mortality in treated hypertensive adults. Journal of Hypertension, 33, pp. 2046-2053. (doi: 10.1097/hjh.0000000000000659)

Butcher, C., Mareev, Y., Markides, V., Mason, M., Wong, T., Cleland, J.G.F. (2015) Cardiac resynchronization therapy update: evolving indications, expanding benefit? Current Cardiology Reports, 17, (doi: 10.1007/s11886-015-0641-5)

Frankenstein, L., Fröhlich, H., Cleland, J. G.F. (2015) Multidisciplinary approach for patients hospitalized with heart failure. Revista Española de Cardiología (English Edition), 68, pp. 885-891. (doi: 10.1016/j.rec.2015.05.008)

Jhund, P., McMurray, J. J.V., Chaturvedi, N., Brunel, P., Desai, A. S., Finn, P. V., Haffner, S. M., Solomon, S. D., Weinrauch, L. A., Claggett, B. L., Pfeffer, M. A. (2015) Mortality following a cardiovascular or renal event in patients with type 2 diabetes in the ALTITUDE trial. European Heart Journal, 36, pp. 2463-2469. (doi: 10.1093/eurheartj/ehv295)

Cleland, J. G.F., Freemantle, N. (2015) QRS morphology as a predictor of the response to cardiac resynchronisation therapy: fact or fashion? Heart, 101, pp. 1441-1443. (doi: 10.1136/heartjnl-2015-307553)

Wannamethee, S. G., Welsh, P., Papacosta, O., Lennon, L., Whincup, P. H., Sattar, N. (2015) Copeptin, insulin resistance, and risk of incident diabetes in older men. Journal of Clinical Endocrinology and Metabolism, 100, pp. 3332-3339. (doi: 10.1210/JC.2015-2362)

Harrison, J. K., Clegg, A., Conroy, S. P., Young, J. (2015) Managing frailty as a long-term condition. Age and Ageing, 44, pp. 732-735. (doi: 10.1093/ageing/afv085)

Platz, E., Jhund, P. S., Campbell, R. T., McMurray, J. (2015) Assessment and prevalence of pulmonary oedema in contemporary acute heart failure trials: a systematic review. European Journal of Heart Failure, 17, pp. 906-916. (doi: 10.1002/ejhf.321)

Damy, T., Hobkirk, J., Walters, M., Ciobanu, A., Rigby, A. S., Kallvikbacka-Bennett, A., Guellich, A., Dubois-Randé, J.-L., Hittinger, L., Clark, A. L., Cleland, J. G.F. (2015) Development of a human model for the study of effects of hypoxia, exercise, and sildenafil on cardiac and vascular function in chronic heart failure. Journal of Cardiovascular Pharmacology, 66, pp. 229-238. (doi: 10.1097/FJC.0000000000000262)

Dierckx, R., Cleland, J. G.F., Pellicori, P., Zhang, J., Goode, K., Putzu, P., Boyalla, V., Clark, A. L. (2015) If home telemonitoring reduces mortality in heart failure, is this just due to better guideline-based treatment? Journal of Telemedicine and Telecare, 21, pp. 331-339. (doi: 10.1177/1357633X15574947)

Stut, W., Deighan, C., Cleland, J. G., Jaarsma, T. (2015) Adherence to self-care in patients with heart failure in the HeartCycle study. Patient Preference and Adherence, 9, pp. 1195-1206. (doi: 10.2147/PPA.S88482)

Morris, R. W. et al. (2015) Heavier smoking may lead to a relative increase in waist circumference: evidence for a causal relationship from a Mendelian randomisation meta-analysis. The CARTA consortium: Table 1. BMJ Open, 5, (doi: 10.1136/bmjopen-2015-008808)

Quinn, T. J., Alghamdi, J., Padmanabhan, S., Porteous, D. J., Smith, B. H., Hocking, L., Deary, I. J., Gallacher, J., Messow, M., Stott, D. J. (2015) Association between cognition and gene polymorphisms involved in thrombosis and haemostasis. Age, 37, pp. 80. (doi: 10.1007/s11357-015-9820-y)

Jhund, P. S., Anand, I. S., Komajda, M., Claggett, B. L., McKelvie, R. S., Zile, M. R., Carson, P. E., McMurray, J. J.V. (2015) Changes in N-terminal pro-B-type natriuretic peptide levels and outcomes in heart failure with preserved ejection fraction: an analysis of the I-Preserve study. European Journal of Heart Failure, 17, pp. 809-817. (doi: 10.1002/ejhf.274)

Jackson, C. E., Haig, C., Welsh, P., Dalzell, J. R., Tsorlalis, I. K., McConnachie, A., Preiss, D., McInnes, I. B., Sattar, N., Petrie, M. C., Gardner, R. S., McMurray, J. J.V. (2015) Combined free light chains are novel predictors of prognosis in heart failure. JACC: Heart Failure, 3, pp. 618-625. (doi: 10.1016/j.jchf.2015.03.014)

Blyth, M., Anthony, I., Francq, B., Brooksbank, K., Downie, P., Powell, A., Jones, B., MacLean, A., McConnachie, A., Norrie, J. (2015) Diagnostic accuracy of the Thessaly test, standardised clinical history and other clinical examination tests (Apley's, McMurray's and joint line tenderness) for meniscal tears in comparison with magnetic resonance imaging diagnosis. Health Technology Assessment, 19, pp. 1-62. (doi: 10.3310/hta19620)

Rush, C. J., Campbell, R. T., Jhund, P. S., Connolly, E. C., Preiss, D., Gardner, R. S., Petrie, M. C., McMurray, J. J.V. (2015) Falling cardiovascular mortality in heart failure with reduced ejection fraction and implications for clinical trials. JACC: Heart Failure, 3, pp. 603-614. (doi: 10.1016/j.jchf.2015.03.013)

Menni, C. et al. (2015) Metabolomic identification of a novel pathway of blood pressure regulation involving hexadecanedioate. Hypertension, 66, pp. 422-429. (doi: 10.1161/HYPERTENSIONAHA.115.05544)

Cleland, J. G.F., Mareev, Y., Linde, C. (2015) Reflections on EchoCRT: sound guidance on QRS duration and morphology for CRT? European Heart Journal, 36, pp. 1948-1951. (doi: 10.1093/eurheartj/ehv264)

Askevold, E. T., Gullestad, L., Nymo, S., Kjekshus, J., Yndestad, A., Latini, R., Cleland, J. G.F., McMurray, J. J.V., Aukrust, P., Ueland, T. (2015) Secreted frizzled related protein 3 in chronic heart failure: analysis from the controlled rosuvastatin multinational trial in heart failure (CORONA) PLoS ONE, 10, (doi: 10.1371/journal.pone.0133970)

Joshi, P. K. et al. (2015) Directional dominance on stature and cognition in diverse human populations. Nature, 523, pp. 459-462. (doi: 10.1038/nature14618)

Raphael, C. E., Finegold, J. A., Barron, A. J., Whinnett, Z. I., Mayet, J., Linde, C., Cleland, J. G.F., Levy, W. C., Francis, D. P. (2015) The effect of duration of follow-up and presence of competing risk on lifespan-gain from implantable cardioverter defibrillator therapy: who benefits the most? European Heart Journal, 36, pp. 1676-1688. (doi: 10.1093/eurheartj/ehv102)

Mentz, R. J., Metra, M., Cotter, G., Milo, O., McKendry, C., Chiswell, K., Davison, B. A., Cleland, J. G.F., Bloomfield, D. M., Dittrich, H. C., Fiuzat, M., Ponikowski, P., Givertz, M. M., Voors, A. A., Teerlink, J. R., O'Connor, C. M. (2015) Early vs. late worsening heart failure during acute heart failure hospitalization: insights from the PROTECT trial. European Journal of Heart Failure, 17, pp. 697-706. (doi: 10.1002/ejhf.308)

Ferrari, R., Böhm, M., Cleland, J. G.F., Paulus, W. J.S., Pieske, B., Rapezzi, C., Tavazzi, L. (2015) Heart failure with preserved ejection fraction: uncertainties and dilemmas. European Journal of Heart Failure, 17, pp. 665-671. (doi: 10.1002/ejhf.304)

Mccallum, L., Panniyammakal, J., Hastie, C. E., Hewitt, J., Patel, R., Jones, G. C., Muir, S., Walters, M., Sattar, N., Dominiczak, A., Padmanabhan, S. (2015) Longitudinal blood pressure control, long-term mortality and predictive utility of serum liver enzymes and bilirubin in hypertensive patients. Hypertension, 66, pp. 37-43. (doi: 10.1161/HYPERTENSIONAHA.114.04915)

Carrick, D., Haig, C., Rauhalammi, S., Ahmed, N., Mordi, I., McEntegart, M., Petrie, M., Eteiba, H., Lindsay, M., Watkins, S., Hood, S., Davie, A., Marous, A., Sattar, N., Welsh, P., Tzemos, N., Radjenovic, A., Ford, I., Oldroyd, K., Berry, C. (2015) Pathophysiology of LV remodeling in survivors of STEMI : inflammation, remote myocardium, and prognosis. JACC: Cardiovascular Imaging, 8, pp. 779-789. (doi: 10.1016/j.jcmg.2015.03.007)

Pellicori, P., Kallvikbacka-Bennett, A., Dierckx, R., Zhang, J., Putzu, P., Cuthbert, J., Boyalla, V., Shoaib, A., Clark, A. L., Cleland, J. G.F. (2015) Prognostic significance of ultrasound-assessed jugular vein distensibility in heart failure. Heart, 101, pp. 1149-1158. (doi: 10.1136/heartjnl-2015-307558)

Zannad, F., Greenberg, B., Cleland, J. G.F., Gheorghiade, M., van Veldhuisen, D. J., Mehra, M. R., Anker, S. D., Byra, W. M., Fu, M., Mills, R. M. (2015) Rationale and design of a randomized, double-blind, event-driven, multicentre study comparing the efficacy and safety of oral rivaroxaban with placebo for reducing the risk of death, myocardial infarction or stroke in subjects with heart failure and significant coronary artery disease following an exacerbation of heart failure: the COMMANDER HF trial. European Journal of Heart Failure, 17, pp. 735-742. (doi: 10.1002/ejhf.266)

Lip, S., Carlin, C., McCallum, L., Touyz, R.H., Dominiczak, A.F., Padmanabhan, S. (2015) Incidence and prognosis of cancer associated with digoxin and common antihypertensive drugs. Journal of Hypertension, 33, pp. e45. (doi: 10.1097/01.hjh.0000467465.54504.ae)

Inglis, S. C., Conway, A., Cleland, J. G.F., Clark, R. A. (2015) Is age a factor in the success or failure of remote monitoring in heart failure? Telemonitoring and structured telephone support in elderly heart failure patients. European Journal of Cardiovascular Nursing, 14, pp. 248-255. (doi: 10.1177/1474515114530611)

Clarke, T.-K., Hall, L.S., Fernandez-Pujals, A.M., MacIntyre, D.J., Thomson, P., Hayward, C., Smith, B.H., Padmanabhan, S., Hocking, L.J., Deary, I.J., Porteous, D.J., McIntosh, A.M. (2015) Major depressive disorder and current psychological distress moderate the effect of polygenic risk for obesity on body mass index. Translational Psychiatry, 5, (doi: 10.1038/tp.2015.83)

Goncalves, A., Jhund, P.S., Claggett, B., Shah, A.M., Konety, S., Butler, K., Kitzman, D.W., Rosamond, W., Fuchs, F.D., Solomon, S.D. (2015) Relationship between alcohol consumption and cardiac structure and function in the elderly: the atherosclerosis tisk in communities study. Circulation: Cardiovascular Imaging, 8, (doi: 10.1161/circimaging.114.002846)

Kristensen, S. L., Jhund, P. S., Køber, L., McKelvie, R. S., Zile, M. R., Anand, I. S., Komajda, M., Cleland, J. G.F., Carson, P. E., McMurray, J. J.V. (2015) Relative importance of history of heart failure hospitalization and N-terminal pro–B-type natriuretic peptide level as predictors of outcomes in patients with heart failure and preserved ejection fraction. JACC: Heart Failure, 3, pp. 478-486. (doi: 10.1016/j.jchf.2015.01.014)

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Costanzo, P., Cleland, J. G.F., Pellicori, P., Clark, A. L., Hepburn, D., Kilpatrick, E. S., Perrone-Filardi, P., Zhang, J., Atkin, S. L. (2015) The obesity paradox in type 2 diabetes mellitus: relationship of body mass index to prognosis: a cohort study. Annals of Internal Medicine, 162, pp. 610-618. (doi: 10.7326/M14-1551)

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Filippatos, G., Khan, S. S., Ambrosy, A. P., Cleland, J. G.F., Collins, S. P., Lam, C. S.P., Angermann, C. E., Ertl, G., Dahlström, U., Hu, D., Dickstein, K., Perrone, S. V., Ghadanfar, M., Bermann, G., Noe, A., Schweizer, A., Maier, T., Gheorghiade, M. (2015) International REgistry to assess medical practice with lOngitudinal obseRvation for Treatment of Heart Failure (REPORT-HF): rationale for and design of a global registry. European Journal of Heart Failure, 17, pp. 527-533. (doi: 10.1002/ejhf.262)

Davison, B. A., Metra, M., Cotter, G., Massie, B. M., Cleland, J. G.F., Dittrich, H. C., Edwards, C., Filippatos, G., Givertz, M. M., Greenberg, B., Ponikowski, P., Voors, A. A., O’Connor, C. M., Teerlink, J. R. (2015) Worsening heart failure following admission for acute heart failure: a pooled analysis of the PROTECT and RELAX-AHF studies. JACC: Heart Failure, 3, pp. 395-403. (doi: 10.1016/j.jchf.2015.01.007)

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Feinstein, M. J., Jhund, P., Kang, J., Ning, H., Maggioni, A., Wikstrand, J., Kjekshus, J., Tavazzi, L., McMurray, J., Lloyd-Jones, D. M. (2015) Do statins reduce the risk of myocardial infarction in patients with heart failure? A pooled individual-level reanalysis of CORONA and GISSI-HF. European Journal of Heart Failure, 17, pp. 434-441. (doi: 10.1002/ejhf.247)

Menni, C., Mangino, M., Cecelja, M., Psatha, M., Brosnan, M. J., Trimmer, J., Mohney, R. P., Chowienczyk, P., Padmanabhan, S., Spector, T. D., Valdes, A. M. (2015) Metabolomic study of carotid–femoral pulse-wave velocity in women. Journal of Hypertension, 33, pp. 791-796. (doi: 10.1097/HJH.0000000000000467)

Abdul-Rahim, A. H., Perez, A.-C., Fulton, R. L., Jhund, P. S., Latini, R., Tognoni, G., Wikstrand, J., Kjekshus, J., Lip, G. Y.H., Maggioni, A. P., Tavazzi, L., Lees, K. R., McMurray, J. (2015) Risk of stroke in chronic heart failure patients without atrial fibrillation: analysis of the controlled rosuvastatin in multinational trial heart failure (corona) and the gruppo italiano per lo studio della sopravvivenza nell'insufficienza cardiaca-heart failure (gissi-hf) trials. Circulation, 131, pp. 1486-1494. (doi: 10.1161/CIRCULATIONAHA.114.013760)

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Pellicori, P., Zhang, J., Lukaschuk, E., Joseph, A. C., Bourantas, C. V., Loh, H., Bragadeesh, T., Clark, A. L., Cleland, J. G.F. (2015) Left atrial function measured by cardiac magnetic resonance imaging in patients with heart failure: clinical associations and prognostic value. European Heart Journal, 36, pp. 733-742. (doi: 10.1093/eurheartj/ehu405)

Vazir, A., Claggett, B., Jhund, P., Castagno, D., Skali, H., Yusuf, S., Swedberg, K., Granger, C.B., McMurray, J.J.V., Pfeffer, M. A., Solomon, S.D. (2015) Prognostic importance of temporal changes in resting heart rate in heart failure patients: an analysis of the CHARM program. European Heart Journal, 36, pp. 669-675. (doi: 10.1093/eurheartj/ehu401)

Jankowska, E. A., Wojtas, K., Kasztura, M., Mazur, G., Butrym, A., Kalicinska, E., Rybinska, I., Skiba, J., von Haehling, S., Doehner, W., Anker, S. D., Banasiak, W., Cleland, J. G.F., Ponikowski, P. (2015) Bone marrow iron depletion is common in patients with coronary artery disease. International Journal of Cardiology, 182, pp. 517-522. (doi: 10.1016/j.ijcard.2014.10.006)

Metra, M., Cotter, G., El-Khorazaty, J., Davison, B. A., Milo, O., Carubelli, V., Bourge, R. C., Cleland, J. G., Jondeau, G., Krum, H., O'Connor, C. M., Parker, J. D., Torre-Amione, G., van Veldhuisen, D. J., Rainisio, M., Kobrin, I., McMurray, J. J., Teerlink, J. R. (2015) Acute heart failure in the elderly: differences in clinical characteristics, outcomes, and prognostic factors in the VERITAS Study. Journal of Cardiac Failure, 21, pp. 179-88. (doi: 10.1016/j.cardfail.2014.12.012)

Harrison, J. K., Clipsham, L. E., Cooke, C. M., Warwick, G., Burton, J. O. (2015) Establishing a supportive care register improves end-of-life care for patients with advanced chronic kidney disease. Nephron, 129, pp. 209-213. (doi: 10.1159/000371888)

Padmanabhan, S., Caulfield, M., Dominiczak, A. (2015) Genetic and molecular aspects of hypertensin. Circulation Research, 116, pp. 937-959. (doi: 10.1161/CIRCRESAHA.116.303647)

Pellicori, P., Cleland, J. G.F. (2015) Is the epidemic of heart disease really over or just evolving? American Journal of Medicine, 128, pp. e17. (doi: 10.1016/j.amjmed.2014.09.018)

Dierckx, R., Cleland, J. G.F., Parsons, S., Putzu, P., Pellicori, P., Dicken, B., Boyalla, V., Clark, A. L. (2015) Prescribing patterns to optimize heart rate: analysis of 1,000 consecutive outpatient appointments to a single heart failure clinic over a 6-month period. JACC: Heart Failure, 3, pp. 224-230. (doi: 10.1016/j.jchf.2014.11.003)

Khand, A. U., Chew, P. G., Douglas, H., Jones, J., Jan, A., Cleland, J.G.F. (2015) The effect of carvedilol on b-type natriuretic peptide and cardiac function in patients with heart failure and persistent atrial fibrillation. Cardiology, 130, pp. 153-158. (doi: 10.1159/000368746)

McCallum, L., Lip, S., Padmanabhan, S. (2015) The hidden hand of chloride in hypertension. Pflügers Archiv - European Journal of Physiology, 467, pp. 595-603. (doi: 10.1007/s00424-015-1690-8)

Pellicori, P., Cleland, J. G.F. (2015) Update on management of heart failure with preserved ejection fraction. Current Opinion in Cardiology, 30, pp. 173-178. (doi: 10.1097/HCO.0000000000000152)

Badar, A. A., Perez-Moreno, A. C., Hawkins, N. M., Brunton, A. P.T., Jhund, P. S., Wong, C. M., Solomon, S. D., Granger, C. B., Yusuf, S., Pfeffer, M. A., Swedberg, K., Gardner, R. S., Petrie, M. C., McMurray, J. J.V. (2015) Clinical characteristics and outcomes of patients with angina and heart failure in the CHARM (Candesartan in Heart Failure Assessment of Reduction in Mortality and Morbidity) programme. European Journal of Heart Failure, 17, pp. 196-204. (doi: 10.1002/ejhf.221)

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Wade, K. H., Forouhi, N. G., Cook, D. G., Johnson, P., McConnachie, A., Morris, R. W., Rodriguez, S., Ye, Z., Ebrahim, S., Padmanabhan, S., Watt, G., Bruckdorfer, K. R., Wareham, N. J., Whincup, P. H., Chanock, S., Sattar, N., Lawlor, D. A., Davey Smith, G., Timpson, N. J. (2015) Variation in the SLC23A1 gene does not influence cardiometabolic outcomes to the extent expected given its association with L-ascorbic acid. American Journal of Clinical Nutrition, 101, pp. 202-209. (doi: 10.3945/ajcn.114.092981)

Metra, M., Mentz, R. J., Chiswell, K., Bloomfield, D. M., Cleland, J. G.F., Cotter, G., Davison, B. A., Dittrich, H. C., Fiuzat, M., Givertz, M. M., Lazzarini, V., Mansoor, G. A., Massie, B. M., Ponikowski, P., Teerlink, J. R., Voors, A. A., O'Connor, C. M. (2015) Acute heart failure in elderly patients: worse outcomes and differential utility of standard prognostic variables. Insights from the PROTECT trial. European Journal of Heart Failure, 17, pp. 109-118. (doi: 10.1002/ejhf.207)

Dickstein, K., Normand, C., Anker, S.D., Auricchio, A., Lundqvist Blomstrom, C., Bogale, N., Cleland, J., Filippatos, G., Gasparini, M., Gitt, A., Hindricks, G., Kuck, K.-H., Ponikowski, P., Stellbrink, C., Ruschitzka, F., Linde, C. (2015) European cardiac resynchronization therapy survey II: rationale and design. Europace, 17, pp. 137-141. (doi: 10.1093/europace/euu312)

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What types of healthcare data do we use?

  • Research cohorts: our researchers have substantial experience and expertise working with the UK Biobank cohort.
  • Linked routine healthcare data: West of Scotland Safe Haven, Clinical Practice Research Datalink (CPRD), Secure Anonymised Data Linkage (SAIL) Wales, Understanding Pathways into Care homes using Data (UnPiCD study) including linkage to national renal and cancer registries.
  • Trial data: individual participant-level data (IPD) from trials via publicly available data-sharing platforms (e.g., Vivli), Glasgow-run repositories for trial IPD (Virtual Trials Archives), and Glasgow-generated IPD from practice-changing trials in heart failure, stroke and chronic kidney disease.

What can we offer with our healthcare data?

  • Practice-changing evidence-based-medicine.
  • Pilot data for grant/funding applications.
  • Strong links with industry partners.
  • Strong collaboration with NHS data providers.