Biomarkers
We measure blood-based biomarkers in observational studies and intervention studies and then use that information to understand the causes and consequences of cardiometabolic disease.
Staff
Publications
2024
Greenlees, C., Hosseinzadeh, S., Delles, C., Mcginnigle, E. (2024) Hypertension evaluation and management in new young patients: are we doing our female patients a disservice? Blood Pressure, 33, (doi: 10.1080/08037051.2024.2387909)
Smith, C., Wallis, S., Katsas, G., Dincarslan, O., Dawson, J., Cameron, A. (2024) Impact of European Stroke Organisation secondary prevention guideline for ischaemic stroke / transient ischaemic attack. Journal of Stroke and Cerebrovascular Diseases, 33, (doi: 10.1016/j.jstrokecerebrovasdis.2024.108034)
De Biase, N., Del Punta, L., L'Hoyes, W., Pellicori, P., Cleland, J. G.F., Masini, G., Gargani, L., Moura-Ferreira, S., Hoedemakers, S., Di Fiore, V., Herbots, L., Stassen, J., Mengozzi, A., Armenia, S., Taddei, S., Masi, S., Verwerft, J., Pugliese, N. R. (2024) Associations of iron deficiency with cardiac function, congestion, exercise capacity and prognosis in heart failure. European Journal of Heart Failure,
Osmanska, J., Petrie, M. C., Docherty, K. F., Lee, M. M.Y., McMurray, J. J.V., Campbell, R. (2024) Subcutaneous furosemide in heart failure: a systematic review. European Heart Journal: Cardiovascular Pharmacotherapy, (doi: 10.1093/ehjcvp/pvae083)
Averbuch, T., Lee, S. F., Zagorski, B., Pandey, A., Petrie, M. C., Biering‐Sorensen, T., Xie, F., Van Spall, H. G.C. (2024) Long‐term clinical outcomes and healthcare resource utilization in male and female patients following hospitalization for heart failure. European Journal of Heart Failure, (doi: 10.1002/ejhf.3499)
Main, A., Mary, S., Sin, Y. Y., Wright, T. A., Ling, J., Blair, C. M., Smith, G. L., Fuller, W., Baillie, G. S. (2024) SUMOylation of cardiac myosin binding protein-C reduces its phosphorylation and results in impaired relaxation following treatment with isoprenaline. International Journal of Biochemistry and Cell Biology, 176, (doi: 10.1016/j.biocel.2024.106668)
Rochmawati, I. D., Deo, S., Lees, J. S., Mark, P. B., Sattar, N., Celis-Morales, C., Pell, J. P., Welsh, P., Ho, F. K. (2024) Adding traditional and emerging biomarkers for risk assessment in secondary prevention: a prospective cohort study of 20,656 patients with cardiovascular disease. European Journal of Preventive Cardiology, (doi: 10.1093/eurjpc/zwae352)
Xiong, X., Lui, D. T.W., Ju, C., Zhou, Z., Xu, C., Welsh, P., Sattar, N., Celis-Morales, C., Pell, J. P., Wong, I. C.K., Wong, C. K.H., Ho, F. (2024) Associations of serum lipid traits with fracture and osteoporosis: a prospective cohort study from the UK Biobank. Journal of Cachexia, Sarcopenia and Muscle, (doi: 10.1002/jcsm.13611)
Dieden, A., Girerd, N., Ottosson, F., Molvin, J., Pareek, M., Melander, O., Bachus, E., Råstam, L., Lindblad, U., Daka, B., Leósdóttir, M., Nilsson, P. M., Olsen, M. H., Clark, A. L., Cleland, J. G.F., Delles, C., González, A., Lamiral, Z., Duarte, K., Rossignol, P., Zannad, F., Gudmundsson, P., Jujić, A., Magnusson, M. (2024) Proteomic biomarkers and pathway analysis for progression to heart failure in three epidemiological representative cohorts. European Journal of Heart Failure, (doi: 10.1002/ejhf.3502)
Foley, P.W., Kalra, P.R., Cleland, J.G.F., Petrie, M.C., Kalra, P.A., Squire, I., Campbell, P., Chapman, C., Donnelly, P., Graham, F., Hannah, A., Lang, N.N., Matthews, I., Leslie, S.J., Pellicori, P., Piper, S., Ray, R., Savage, H.O., Spencer, C., Walsh, J., Wong, Y., Ford, I. (2024) Effect of correcting iron deficiency on the risk of serious infection in heart failure insights from the IRONMAN trial. European Journal of Heart Failure, (doi: 10.1002/ejhf.3504)
Pontiroli, A. E., Tagliabue, E., Madotto, F., Leoni, O., Antonelli, B., Carluccio, E., Bandera, F., Galati, G., Pellicori, P., Lund, L. H., Ambrosio, G. (2024) Association of non-cardiac comorbidities and sex with long-term re-hospitalization for heart failure. European Journal of Internal Medicine,
Lu, H., Claggett, B. L., Packer, M., Pfeffer, M. A., Swedberg, K., Rouleau, J., Zile, M. R., Lefkowitz, M., Desai, A. S., Jhund, P. S., McMurray, J. J.V., Solomon, S. D., Vaduganathan, M. (2024) Visit‐to‐visit changes in heart rate in heart failure: A pooled participant‐level analysis of the PARADIGM‐HF and PARAGON‐HF trials. European Journal of Heart Failure, (doi: 10.1002/ejhf.3487)
Riddell, A., Flynn, A., Bergugnat, H., Dowsett, L. B., Miller, A. A. (2024) SDMA as a marker and mediator in cerebrovascular disease. Clinical Science, 138, pp. 1305-1323. (doi: 10.1042/CS20241021)
Alharbi, A., Nurfianti, A., Mullen, R. F., McClure, J. D., Miller, W. H. (2024) The effectiveness of simulation-based learning (SBL) on students' knowledge and skills in nursing programs: a systematic review. BMC Medical Education, 24, (doi: 10.1186/s12909-024-06080-z)
Varga, C. R., Cleland, J. G.F., Abraham, W. T., Lip, G. Y.H., Leyva, F., Hatamizadeh, P. (2024) Implantable cardioverter defibrillator and resynchronization therapy in patients with overt chronic kidney disease. Journal of the American College of Cardiology, 84, pp. 1342-1362. (doi: 10.1016/j.jacc.2024.05.081)
Ho, F., Allan, M., Shao, H., Man, K. K.C., Jani, B. D., Lyall, D., Hastie, C., Fleming, M., Mackay, D., Cleland, J. G.F., Delles, C., Dundas, R., Lewsey, J., Ip, P., Wong, I., Welsh, P., Pearce, A., Wright, C. M., Minnis, H., Katikireddi, V., Pell, J. P. (2024) Maternal and pregnancy factors contributing to the association between area deprivation and infant mortality in England: a retrospective cohort study. Lancet Regional Health - Europe, (doi: 10.1016/j.lanepe.2024.101075)
Lee, M., Petrie, M. C., Cleland, J. G.F., Donnelly, P., Francis, M., Hannah, A., Japp, A. G., Labinjoh, C., Lang, N. N., Mainsty, C., Petrie, C. J., Piper, S. E., Williams, S. G., Ford, I., Kalra, P. R., IRONMAN Trial Investigators, (2024) Administration of ferric derisomaltose for iron deficiency and heart failure during hospital admission or at the clinic – insights from the IRONMAN trial. European Journal of Heart Failure, 26, pp. 2293-2295. (doi: 10.1002/ejhf.3394)
Liu, Q., Celis-Morales, C., Lees, J. S., Sattar, N., Ho, F., Pell, J. P., Mark, P. B., Welsh, P. (2024) Change in physical activity and its association with decline in kidney function: A UK Biobank-based cohort study. Journal of Cachexia, Sarcopenia and Muscle, 15, pp. 2046-2055. (doi: 10.1002/jcsm.13551)
Cleland, J. G.F. (2024) Home-time is good, but feeling well is better: patient-journey and quality-home-time as endpoints in heart failure trials and registries. Circulation: Heart Failure, 17, (doi: 10.1161/CIRCHEARTFAILURE.124.012263)
Abdin, A., Jhund, P. S. (2024) Implementation of guideline‐directed medical therapy for heart failure: Progress achieved, work ahead! European Journal of Heart Failure, 26, pp. 2258-2260. (doi: 10.1002/ejhf.3438)
Sliwa, K., Rakisheva, A., Viljoen, C., Pfeffer, T., Simpson, M., Jackson, A. M., Petrie, M. C., van der Meer, P., Al Farhan, H., Jovanova, S., Mbakwem, A., Sinagra, G., Van Craenenbroeck, E., Hoevelmann, J., Johnson, M. R., Mindham, R., Chioncel, O., Kahl, K. G., Rosano, G., Tschöpe, C., Mebazaa, A., Seferovic, P., Bauersachs, J. (2024) Living with peripartum cardiomyopathy: A statement from the Heart Failure Association and the Association of Cardiovascular Nursing and Allied Professions of the European Society of Cardiology. European Journal of Heart Failure, 26, pp. 2143-2154. (doi: 10.1002/ejhf.3377)
Pellicori, P., Cuthbert, J. J., Clark, A. L., Cleland, J. G.F. (2024) Managing water and salt balance in heart failure: Is there anything else to consider other than diet and diuretics? European Journal of Heart Failure, 26, pp. 2140-2142. (doi: 10.1002/ejhf.3374)
Keene, D. et al. (2024) Predictors of the efficacy of His bundle pacing in patients with a prolonged PR interval: A stratified analysis of the HOPE‐HF randomized controlled trial. European Journal of Heart Failure, 26, pp. 2261-2268. (doi: 10.1002/ejhf.3367)
Lee, M., Aimo, A., Bayés-Genís, A. (2024) Reverse cardiac remodelling: VICTORIA for inflammation and cardiac metabolism. European Journal of Heart Failure, 26, pp. 2240-2242. (doi: 10.1002/ejhf.3421)
Yu, Y.-L. et al. (2024) Urinary proteomic signature of mineralocorticoid receptor antagonism by spironolactone: evidence from the HOMAGE trial. Heart, 110, pp. 1180-1187. (doi: 10.1136/heartjnl-2023-323796)
Lee, M. M.Y., Codina, P., Tomasoni, D., Aimo, A. (2024) What’s new in heart failure? October 2024. European Journal of Heart Failure, 26, pp. 2049-2054. (doi: 10.1002/ejhf.3492)
Beazer, J. D., Sillars, A., Beck, S., Christoffersen, C., Ferraz, M. J., Mulder, M., Graham, D., Karlsson, H., Ljunggren, S. A., Gill, J. M. R., Freeman, D. J. (2024) Favourable HDL composition in endurance athletes is not associated with changes in HDL in vitro antioxidant and endothelial anti-inflammatory function. Bioscience Reports, (doi: 10.1042/BSR20241165)
Cheng, L., Hammersley, D., Ragavan, A., Javed, S., Mukhopadhyay, S., Gregson, J., Han, J., Khalique, Z., Lota, A., Pantazis, A., Baksi, A. J., Carr‐White, G., de Marvao, A., Ware, J., Tayal, U., Pennell, D. J., Cleland, J. G.F., Prasad, S. K., Halliday, B. P. (2024) Long‐term follow‐up of the TRED ‐ HF trial: Implications for therapy in patients with dilated cardiomyopathy and heart failure remission. European Journal of Heart Failure, (doi: 10.1002/ejhf.3475)
Wang, X., Pabon, M. A., Cikes, M., Jering, K., Mullens, W., Kober, L., Jhund, P. S., Kovacs, A., Merkely, B., Zhou, Y., McMurray, J. J.V., Shah, A. M., Hegde, S. M., Claggett, B., Pfeffer, M. A., Solomon, S. D. (2024) Sex differences in cardiac structure and function following acute myocardial infarction: Insights from the PARADISE‐MI echocardiographic substudy. European Journal of Heart Failure, (doi: 10.1002/ejhf.3472)
Jhund, P. S., Talebi, A., Henderson, A. D., Claggett, B. L., Vaduganathan, M., Desai, A. S., Lam, C. S.P., Pitt, B., Senni, M., Shah, S. J., Voors, A. A., Zannad, F., Solomon, S. D., McMurray, J. J.V. (2024) Mineralocorticoid receptor antagonists in heart failure: an individual patient level meta-analysis. Lancet, 404, pp. 1119-1131. (doi: 10.1016/S0140-6736(24)01733-1)
Anderson, J. J., Deo, S. V., Welsh, P., Mackay, D. F., Ho, F. K., Ferguson, L. D., Celis-Morales, C., Gill, J.R., Pell, J. P., Sattar, N. (2024) In which common chronic conditions can (or cannot) obesity and lifestyle factors explain higher concentrations of C-reactive protein? Diabetes, Obesity and Metabolism, (doi: 10.1111/dom.15949)
Pabon, M. A., Vaduganathan, M., Claggett, B. L., Chatur, S., Siqueira, S., Marti‐Castellote, P., de Boer, R. A., Hernandez, A. F., Inzucchi, S. E., Kosiborod, M. N., Lam, C. S.P., Martinez, F., Shah, S. J., Desai, A. S., Jhund, P. S., McMurray, J. J.V., Solomon, S. D., Vardeny, O. (2024) In‐hospital course of patients with heart failure with improved ejection fraction in the DELIVER trial. European Journal of Heart Failure, (doi: 10.1002/ejhf.3410)
Valentova, M., Vatic, M., Garfias-Veitl, T., Sandek, A., Bekfani, T., Jankowska, E. A., Cleland, J. G.F., Clark, A. L., Lainscak, M., Ahmed, A., Jauert, N., Hasenfuss, G., Anker, S. D., Doehner, W., von Haehling, S. (2024) Diabetes mellitus is associated with low exercise capacity and impaired peripheral vasodilation in patients with heart failure – a propensity score-matched stud. Diabetes Research and Clinical Practice,
Greene, S. J. et al. (2024) Cardiovascular and renal treatment in heart failure patients with hyperkalemia or high risk of hyperkalemia: rationale and design of the CARE-HK in HF registry. Journal of Cardiac Failure, (doi: 10.1016/j.cardfail.2024.08.048)
Zhou, M., Mary, S., Delles, C., Padmanabhan, S., Graham, D., McBride, M. W., Dominiczak, A. (2024) Insights into uromodulin and blood pressure. Current Hypertension Reports, (doi: 10.1007/s11906-024-01317-0)
Cuthbert, J. J., Cleland, J. G. F., Pellicori, P., Clark, A. L. (2024) Natriuresis guided diuresis in patients admitted to hospital with heart failure – barking up the wrong tree? Journal of Cardiac Failure,
Coats, C. J. et al. (2024) Cardiac biomarkers and effects of aficamten in obstructive hypertrophic cardiomyopathy: the SEQUOIA-HCM trial. European Heart Journal, (doi: 10.1093/eurheartj/ehae590)
Lu, H., Claggett, B. L., Packer, M., Pfeffer, M. A., Lam, C. S.P., Zile, M. R., Desai, A. S., Jhund, P., Lefkowitz, M., McMurray, J. J.V., Solomon, S. D., Vaduganathan, M. (2024) Sacubitril/valsartan reduces incident anaemia and iron therapy utilization in heart failure: The PARAGON‐HF trial. European Journal of Heart Failure, (doi: 10.1002/ejhf.3414)
Morrow, A. et al. (2024) Zibotentan in microvascular angina: a randomized, placebo-controlled, crossover trial. Circulation, (doi: 10.1161/CIRCULATIONAHA.124.069901)
Al-Abdullah, L., Ahern, A., Welsh, P., Logue, J. (2024) A predictive model for medium-term weight loss response in people with type 2 diabetes engaging in behavioural weight management interventions. Diabetes, Obesity and Metabolism, 26, pp. 3653-3662. (doi: 10.1111/dom.15706)
van der Meer, P., van Essen, B., Viljoen, C., Böhm, M., Jackson, A., Hilfiker-Kleiner, D., Hoevelmann, J., Mebazaa, A., Farhan, H. A., Goland, S., Ouwerkerk, W., Petrie, M. C., Seferović, P. M., Tromp, J., Sliwa, K., Bauersachs, J. (2024) Bromocriptine treatment and outcomes in peripartum cardiomyopathy: the EORP PPCM registry. European Heart Journal, (doi: 10.1093/eurheartj/ehae559)
Butt, J., Jhund, P. S., Docherty, K. F., Claggett, B. L., Vaduganathan, M., Bachus, E., Hernandez, A. F., Lam, C. S.P., Inzucchi, S. E., Martinez, F. A., de Boer, R. A., Kosiborod, M. N., Desai, A. S., Køber, L., Ponikowski, P., Sabatine, M. S., Solomon, S. D., McMurray, J. J.V. (2024) Dapagliflozin and timing of prior heart failure hospitalization a patient-level meta-analysis of DAPA-HF and DELIVER. JACC: Heart Failure, 12, pp. 1586-1599. (doi: 10.1016/j.jchf.2024.01.018)
Seferović, P. M., Paulus, W. J., Rosano, G., Polovina, M., Petrie, M. C., Jhund, P. S., Tschöpe, C., Sattar, N., Piepoli, M., Papp, Z., Standl, E., Mamas, M. A., Valensi, P., Linhart, A., Lalić, N., Ceriello, A., Döhner, W., Ristić, A., Milinković, I., Seferović, J., Cosentino, F., Metra, M., Coats, A. J.S. (2024) Diabetic myocardial disorder. A clinical consensus statement of the Heart Failure Association of the ESC and the ESC Working Group on Myocardial & Pericardial Diseases. European Journal of Heart Failure, 26, pp. 1893-1903. (doi: 10.1002/ejhf.3347)
Ryan, M., Taylor, D., Dodd, M., Spertus, J. A., Kosiborod, M. N., Shaukat, A., Docherty, K. F., Clayton, T., Perera, D., Petrie, M. C., REVIVED-BCIS2 Investigators, (2024) Effect of PCI on health status in ischemic left ventricular dysfunction: insights from REVIVED-BCIS2. JACC: Heart Failure, 12, pp. 1553-1562. (doi: 10.1016/j.jchf.2024.03.010)
Abdin, A., Kondo, T., Böhm, M., Jhund, P. S., Claggett, B. L., Vaduganathan, M., Hernandez, A. F., Lam, C. S.P., Inzucchi, S. E., Martinez, F. A., de Boer, R. A., Desai, A. S., Køber, L., Sabatine, M. S., Petersson, M., Bachus, E., Solomon, S. D., McMurray, J. (2024) Effects of dapagliflozin according to QRS duration across the spectrum of left ventricular ejection fraction: an analysis of DAPA-HF and DELIVER. European Journal of Heart Failure, 26, pp. 1952-1963. (doi: 10.1002/ejhf.3350)
Reza, N., Pellicori, P., Starling, R. C. (2024) REVOLUTION in heart failure care and SELECT highlights from the European Society of Cardiology-Heart Failure Association Heart Failure and World Congress on Acute Heart Failure 2024. Journal of Cardiac Failure, 30, pp. 1157-1160. (doi: 10.1016/j.cardfail.2024.05.004)
Butt, J. H., McMurray, J. J.V., Claggett, B. L., Jhund, P. S., Neuen, B. L., McCausland, F., Desai, A., Lam, C. S.P., Pitt, B., Pfeffer, M. A., Packer, M., Beldhuis, I., Voors, A. A., Zannad, F., Heerspink, H. J.L., Solomon, S. D., Vaduganathan, M. (2024) Therapeutic effects of heart failure medical therapies on standardized kidney outcomes: Comprehensive individual participant-level analysis of 6 randomized clinical trials. Circulation, (doi: 10.1161/circulationaha.124.071110)
Matsumoto, S., Henderson, A. D., Shen, L., Kondo, T., Yang, M., Campbell, R. T., Anand, I. S., de Boer, R. A., Desai, A. S., Lam, C. S.P., Maggioni, A. P., Martinez, F. A., Packer, M., Redfield, M. M., Rouleau, J. L., Van Veldhuisen, D. J., Vaduganathan, M., Zannad, F., Zile, M. R., Jhund, P. S., Solomon, S. D., McMurray, J. J.V. (2024) Beta‐blocker use and outcomes in patients with heart failure and mildly reduced and preserved ejection fraction. European Journal of Heart Failure, (doi: 10.1002/ejhf.3383)
Ponikowski, P. et al. (2024) Hospitalization of symptomatic patients with heart failure and moderate to severe functional mitral regurgitation treated with MitraClip: insights from RESHAPE-HF2. JACC: Heart Failure, (doi: 10.1016/j.jacc.2024.08.027)
McNeilly, S. et al. (2024) Collagen IV deficiency causes hypertrophic remodeling and endothelium-dependent hyperpolarization in small vessel disease with intracerebral hemorrhage. EBioMedicine, 107, (doi: 10.1016/j.ebiom.2024.105315)
Di Fiore, V., Del Punta, L., De Biase, N., Pellicori, P., Gargani, L., Dini, F. L., Armenia, S., Vigni, M. L., Maremmani, D., Masi, S., Taddei, S., Pugliese, N. R. (2024) Integrative assessment of congestion in heart failure using ultrasound imaging. Internal and Emergency Medicine,
Giannitsis, E., Frey, N., Jhund, P. S. (2024) Improving the rate of heart failure with improved ejection fraction. European Journal of Heart Failure, (doi: 10.1002/ejhf.3427)
Yang, M., Kondo, T., Anand, I. S., de Boer, R. A., Campbell, R. T., Køber, L., Lam, C. S.P., Maggioni, A. P., Martinez, F. A., O'Meara, E., Packer, M., Sabatine, M. S., Kerr Saraiva, J. F., Shah, S. J., Zannad, F., Zile, M. R., Jhund, P. S., Solomon, S. D., McMurray, J. J.V. (2024) Clinical characteristics and outcomes of patients aged 80 years and over with heart failure: Need for better treatment. European Journal of Heart Failure, (doi: 10.1002/ejhf.3417)
Liu, Q., Celis-Morales, C., Sattar, N., Welsh, P. (2024) Association of glycaemic control with intraocular pressure in a large general population: Results from the UK Biobank. Diabetes, Obesity and Metabolism, (doi: 10.1111/dom.15865)
Liu, Q., Celis-Morales, C., Sattar, N., Welsh, P. (2024) Association of glycemic control with intraocular pressure in a large general population: results from the UK Biobank. Diabetes, Obesity and Metabolism, (doi: 10.1111/dom.15865)
Graham, F. J., Guha, K., Cleland, J. G., Kalra, P. R. (2024) Treating iron deficiency in patients with heart failure: what, why, when, how, where and who. Heart, (doi: 10.1136/heartjnl-2022-322030)
McLaren, J., Gao, X., Ghouri, N., Freeman, D. J., Richardson, J., Sattar, N., Gill, J. M.R. (2024) Weight gain leads to greater adverse metabolic responses in South Asian compared with white European men: the GlasVEGAS study. Nature Metabolism, 6, pp. 1632-1645. (doi: 10.1038/s42255-024-01101-z)
Cleland, J., Pellicori, P., Graham, F. J., Lane, R., Petrie, M. C., Ahmed, F., Squire, I. B., Ludman, A., Japp, A., Al-Mohammad, A., Clark, A. L., Szwejkowski, B., Critoph, C., Chong, V., Schiff, R., Nageh, T., Glover, J., McMurray, J. J.V., Thomson, E. A., Robertson, M., Ford, I., Kalra, P. A., Kalra, P. R. (2024) The IRONMAN trial of intravenous iron for heart failure. Adjudication of hospitalizations and deaths. Journal of the American College of Cardiology,
Cameron, A., Arnold, M., Katsas, G., Yang, J., Quinn, T. J., Abdul-Rahim, A. H., Campbell, R., Docherty, K., De Marchis, G. M., Arnold, M., Kahles, T., Nedeltchev, K., Cereda, C., Kaegi, G., Bustamante, A., Montaner, J., Ntaios, G., Foerch, C., Spanaus, K., Von Eckardstein, A., Dawson, J., Katan, M. (2024) Natriuretic peptides to classify risk of atrial fibrillation detection after stroke: analysis of the BIOSIGNAL and PRECISE cohort studies. Neurology, 103, (doi: 10.1212/WNL.0000000000209625)
Elyan, B. M.P., Sullivan, M. K., Hedley, J., De La Mata, N., Webster, A. C., Venugopal, B., Jones, R. J., Lang, N. N., Mark, P. B., Lees, J. S. (2024) The impact of VEGF signalling pathway inhibitors and/or immune checkpoint inhibitors on kidney function over time: a single centre retrospective analysis. BJC Reports, 2, (doi: 10.1038/s44276-024-00081-7)
Cao, T. H., Tay, W. T., Jones, D. J.L., Cleland, J. G.F., Tromp, J., Emmens, J. E., Teng, T.‐H. K., Chandramouli, C., Slingsby, O. C., Anker, S. D., Dickstein, K., Filippatos, G., Lang, C. C., Metra, M., Ponikowski, P., Samani, N. J., Van Veldhuisen, D. J., Zannad, F., Anand, I. S., Lam, C. S.P., Voors, A. A., Ng, L. L. (2024) Heart failure with improved versus persistently reduced left ventricular ejection fraction: A comparison of the BIOSTAT‐CHF (European) study with the ASIAN‐HF registry. European Journal of Heart Failure, (doi: 10.1002/ejhf.3378)
Kazmi, S., Kambhampati, C., Rigby, A. S., Cleland, J. G.F., Kazmi, K. S., Cuthbert, J., Pellicori, P., Clark, A. L. (2024) Disease progression in chronic heart failure is linear: insights from multistate modelling. European Journal of Heart Failure, (doi: 10.1002/ejhf.3400)
Coats, C. J. et al. (2024) Dosing and safety profile of aficamten in symptomatic obstructive hypertrophic cardiomyopathy: results from from SEQUOIA‐HCM. Journal of the American Heart Association, 13, (doi: 10.1161/JAHA.124.035993)
Richardson, S. H., Mackenzie, J., Thekkethil, N., Feng, L., Lee, J., Berry, C., Hill, N., Luo, X., Gao, H. (2024) Cardiac perfusion coupled with a structured coronary network tree. Computer Methods in Applied Mechanics and Engineering, 428, (doi: 10.1016/j.cma.2024.117083)
Gustafsson, F., Petrie, M. C., Komtebedde, J., Swarup, V., Winkler, S., Hasenfuß, G., Borlaug, B. A., Mohan, R. C., Flaherty, J. D., Sverdlov, A. L., Fail, P. S., Chung, E. S., Lurz, P., Lilly, S., Kaye, D. M., Cleland, J. G.F., Cikes, M., Leon, M. B., Cutlip, D. E., van Veldhuisen, D. J., Solomon, S. D., Shah, S. J. (2024) 2-year outcomes of an atrial shunt device in HFpEF/HFmrEF: results from REDUCE LAP-HF II. JACC: Heart Failure, 12, pp. 1425-1438. (doi: 10.1016/j.jchf.2024.04.011)
Sudesh, S., Abraham, W. T., Cleland, J. G.F., Curtis, A. B., Friedman, D. J., Gold, M. R., Kutyifa, V., Linde, C., Tang, A. S., Olivas-Martinez, A., Inoue, L. Y.T., Sanders, G. D., Al-Khatib, S. M. (2024) Cardiac resynchronization therapy in ischemic versus non-ischemic cardiomyopathy: patient-level meta-analysis of seven randomized clinical trials. JACC: Heart Failure,
Rosano, G. M.C. et al. (2024) Differences in presentation, diagnosis and management of heart failure in women. A scientific statement of the Heart Failure Association of the ESC. European Journal of Heart Failure, 26, pp. 1669-1686. (doi: 10.1002/ejhf.3284)
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2023
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2021
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Platz, E., Jhund, P. S. (2021) Risk stratification in patients presenting with acute heart failure. European Heart Journal: Acute Cardiovascular Care, 10, pp. 113-115. (doi: 10.1093/ehjacc/zuab005)
Al Ozairi, E., Alroudhan, D., Alsaeed, D., Voase, N., Hasan, A., Gill, J. M.R., Sattar, N., Welsh, P., Gray, C. M., Boonpor, J., Celis-Morales, C., Gray, S. R. (2021) Skeletal muscle and metabolic health – how do we increase muscle mass and function in people with type 2 diabetes. Journal of Clinical Endocrinology and Metabolism, 106, pp. 309-317. (doi: 10.1210/clinem/dgaa835)
Connelly, P. J., Clark, A., Touyz, R. M., Delles, C. (2021) Transgender adults, gender-affirming hormone therapy and blood pressure: a systematic review. Journal of Hypertension, 39, pp. 223-230. (doi: 10.1097/HJH.0000000000002632)
Gill, D., Cameron, A. C., Burgess, S., Liu, X., Doherty, D. J., Karhunen, V., Abdul-Rahim, A., Taylor-Rowan, M., Zuber, V., Tsao, P. S., Klarin, D., VA Million Veteran Program, , Evangelou, E., Elliott, P., Damrauer, S. M., Quinn, T. J., Dehghan, A., Theodoratou, E., Dawson, J., Tzoulaki, I. (2021) Urate, blood pressure, and cardiovascular disease: evidence from Mendelian randomization and meta-analysis of clinical trials. Hypertension, 77, pp. 383-392. (doi: 10.1161/HYPERTENSIONAHA.120.16547)
Jhund, P. S. et al. (2021) Efficacy of dapagliflozin on renal function and outcomes in patients with heart failure with reduced ejection fraction: results of DAPA-HF. Circulation, 143, pp. 289-309. (doi: 10.1161/CIRCULATIONAHA.120.050391)
Samuel, N. A., Cuthbert, J. J., Brown, O. I., Kazmi, S., Cleland, J. G.F., Rigby, A. S., Clark, A. L. (2021) Relation between thyroid function and mortality in patients with chronic heart failure. American Journal of Cardiology, 139, pp. 57-63. (doi: 10.1016/j.amjcard.2020.10.034)
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Corcoran, D., Radjenovic, A., Mordi, I., Nazir, S. A., Wilson, S. J., Hinder, M., Yates, D. P., Machineni, S., Alcantara, J., Prescott, M. F., Gugliotta, B., Pang, Y., Tzemos, N., Semple, S. I., Newby, D. E., McCann, G. P., Squire, I., Berry, C. (2021) Vascular effects of serelaxin in patients with stable coronary artery disease: a randomized placebo-controlled trial. Cardiovascular Research, 117, pp. 320-329. (doi: 10.1093/cvr/cvz345)
Bekfani, T., Fudim, M., Cleland, J. G.F., Jorbenadze, A., Haehling, S., Lorber, A., Rothman, A. M.‐K., Stein, K., Abraham, W. T., Sievert, H., Anker, S. D. (2021) A current and future outlook on upcoming technologies in the remote monitoring of patients with heart failure. European Journal of Heart Failure, 23, pp. 175-185. (doi: 10.1002/ejhf.2033)
Moreton, F. C., Cullen, B., Dickie, D. A., Lopez Gonzalez, R., Santosh, C., Delles, C., Muir, K. W. (2021) Brain imaging factors associated with progression of subcortical hyperintensities in CADASIL over two year follow up. European Journal of Neurology, 28, pp. 220-228. (doi: 10.1111/ene.14534)
Dobbin, S. J.H., Petrie, M. C., Myles, R. C., Touyz, R. M., Lang, N. N. (2021) Cardiotoxic effects of angiogenesis inhibitors. Clinical Science, 135, pp. 71-100. (doi: 10.1042/CS20200305)
Davison, B. A., Senger, S., Sama, I. E., Koch, G. G., Mebazaa, A., Dickstein, K., Samani, N. J., Metra, M., Anker, S. D., Cleland, J. G., Ng, L. L., Mordi, I. R., Zannad, F., Filippatos, G. S., Hillege, H. L., Ponikowski, P., Veldhuisen, D. J., Lang, C. C., Meer, P., Núñez, J., Bayés‐Genís, A., Edwards, C., Voors, A. A., Cotter, G. (2021) Is acute heart failure a distinctive disorder? An analysis from BIOSTAT‐CHF. European Journal of Heart Failure, 23, pp. 43-57. (doi: 10.1002/ejhf.2077)
He, T., Melgarejo, J. D., Clark, A. L., Yu, Y.‐L., Thijs, L., Díez, J., López, B., González, A., Cleland, J. G., Schanstra, J. P., Vlahou, A., Latosinska, A., Mischak, H., Staessen, J. A., Zhang, Z.‐Y., Jankowski, V. (2021) Serum and urinary biomarkers of collagen type‐I turnover predict prognosis in patients with heart failure. Clinical and Translational Medicine, 11, (doi: 10.1002/ctm2.267)
Willder, J. M., McCall, P., Messow, C.-M., Gillies, M., Berry, C., Shelley, B. (2021) Study protocol for COVID-RV: a multicentre prospective observational cohort study of right ventricular dysfunction in ventilated patients with COVID-19. BMJ Open, 11, (doi: 10.1136/bmjopen-2020-042098)
Mortensen, P., Gao, H., Smith, G., Simitev, R. D. (2021) Addendum: Action potential propagation and block in a model of atrial tissue with myocyte-fibroblast coupling. Mathematical Medicine and Biology, 38, pp. 292-298. (doi: 10.1093/imammb/dqab005)
Jacobs, M., Benovoy, M., Chang, L.-C., Corcoran, D., Berry, C., Arai, A. E., Hsu, L.-Y. (2021) Automated segmental analysis of fully quantitative myocardial blood flow maps by first-pass perfusion cardiovascular magnetic resonance. IEEE Access, 9, pp. 52796-52811. (doi: 10.1109/ACCESS.2021.3070320)
Kamdar, A., Sykes, R., Morrow, A., Mangion, K., Berry, C. (2021) Cardiovascular outcomes of glucose lowering therapy in chronic kidney disease patients: a systematic review with meta-analysis. Reviews in Cardiovascular Medicine, 22, pp. 1479-1490. (doi: 10.31083/j.rcm2204152)
Da Silva Costa, A., Mortensen, P., Hortigon-Vinagre, M. P., van der Heyden, M. A. G., Burton, F. L., Gao, H., Simitev, R. D., Smith, G. L. (2021) Electrophysiology of hiPSC-cardiomyocytes co-cultured with HEK cells expressing the inward rectifier channel. International Journal of Molecular Sciences, 22, (doi: 10.3390/ijms22126621)
Anderson, J. J., Welsh, P., Ho, F. K., Ferguson, L. D., Welsh, C. E., Pellicori, P., Cleland, J. G.F., Forbes, J., Iliodromiti, S., Boyle, J., Lindsay, R., Celis-Morales, C., Gray, S. R., Katikireddi, S. V., Gill, J. M. R., Pell, J. P., Sattar, N. (2021) Ethnic differences in prevalence of actionable HbA1c levels in UK Biobank: implications for screening. BMJ Open Diabetes Research and Care, 9, (doi: 10.1136/bmjdrc-2021-002176)
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Wijkman, M. O., Malachias, M. V.B., Claggett, B. L., Cheng, S., Matsushita, K., Shah, A. M., Jhund, P. S., Coresh, J., Solomon, S. D., Vardeny, O. (2021) Resistance to antihypertensive treatment and long-term risk: The Atherosclerosis Risk in Communities study. Journal of Clinical Hypertension, 23, pp. 1887-1896. (doi: 10.1111/jch.14269)
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Sykes, R., Briscoe, M., Krystofiak, T., Peck, O., Mangion, K., Berry, C. (2021) Type 2 myocardial infarction and myocardial injury: eligibility for novel medical therapy to de-risk clinical trials. Open Heart, 8, (doi: 10.1136/openhrt-2021-001633)
Ang, D. T. Y., Berry, C. (2021) What an interventionalist needs to know about INOCA. Interventional Cardiology Review, 16, (doi: 10.15420/icr.2021.16)
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2020
Brown, R., Welsh, P., Logue, J. (2020) Systematic review of clinical guidelines for lipid-lowering in the secondary prevention of cardiovascular disease events. Open Heart, 7, (doi: 10.1136/openhrt-2020-001396)
Rossitto, G., Mary, S., McAllister, C., Neves, K. B., Haddow, L., Rocchiccioli, J. P., Lang, N. N., Murphy, C. L., Touyz, R. M., Petrie, M. C., Delles, C. (2020) Reduced lymphatic reserve in heart failure with preserved ejection fraction. Journal of the American College of Cardiology, 76, pp. 2817-2829. (doi: 10.1016/j.jacc.2020.10.022)
Lee, M. (2020) Studies of Empagliflozin and its Cardiovascular, Renal and Metabolic Effects in Patients With Diabetes Mellitus (or Prediabetes) and Heart Failure: a Randomized Controlled Trial (SUGAR-DM-HF) (doi: 10.1161/CIR.0000000000000940)
Goncalves Soares, A., Kilpi, F., Fraser, A., Nelson, S. M., Sattar, N., Welsh, P. I., Tilling, K., Lawlor, D. A. (2020) Longitudinal changes in reproductive hormones through the menopause transition in the Avon Longitudinal Study of Parents and Children (ALSPAC) Scientific Reports, 10, (doi: 10.1038/s41598-020-77871-9)
Purcell, C., Daw, P., Kerr, C., Cleland, J., Cowie, A., Dalal, H., Ibbotson, T., Murphy, C., Taylor, R. (2020) Protocol for an implementation study of an evidence-based home cardiac rehabilitation programme for people with heart failure and their caregivers in Scotland (SCOT:REACH-HF) BMJ Open, 10, (doi: 10.1136/bmjopen-2020-040771)
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Ferguson, A. C., Tank, R., Lyall, L. M., Ward, J., Welsh, P., Celis-Morales, C., McQueenie, R., Strawbridge, R. J., Mackay, D. F., Pell, J. P., Smith, D. J., Sattar, N., Cavanagh, J., Lyall, D. M. (2020) Association of SBP and BMI with cognitive and structural brain phenotypes in UK Biobank. Journal of Hypertension, 38, pp. 2482-2489. (doi: 10.1097/HJH.0000000000002579)
Kelly, P., Williamson, C., Baker, G., Davis, A., Broadfield, S., Coles, A., Logan, G., Connell, H., Pell, J. P., Gray, C., Gill, J. M.R. (2020) Beyond cycle lanes and large-scale infrastructure: a scoping review of initiatives that groups and organisations can implement to promote cycling for the Cycle Nation Project. British Journal of Sports Medicine, 54, pp. 1405-1415. (doi: 10.1136/bjsports-2019-101447)
Mangion, K., Loughrey, C., Auger, D. A., McComb, C., Lee, M. M., Corcoran, D., McEntegart, M., Davie, A., Good, R., Lindsay, M., Eteiba, H., Rocchiccioli, J. P., Watkins, S., Hood, S., Shaukat, A., Haig, C., Epstein, F. H., Berry, C. (2020) Displacement encoding with stimulated echoes enables the identification of infarct transmurality early postmyocardial infarction. Journal of Magnetic Resonance Imaging, 52, pp. 1722-1731. (doi: 10.1002/jmri.27295)
Pellicori, P., Ofstad, A. P., Fitchett, D., Zeller, C., Wanner, C., George, J., Zinman, B., Brueckmann, M., Lindenfeld, J. (2020) Early benefits of empagliflozin in patients with or without heart failure: findings from EMPA-REG OUTCOME. ESC Heart Failure, 7, pp. 3401-3407. (doi: 10.1002/ehf2.12891)
Felker, G. M., Solomon, S. D., McMurray, J. J.V., Cleland, J. G.F., Abbasi, S. A., Malik, F. I., Zhang, H., Globe, G., Teerlink, J. R. (2020) Effects of omecamtiv mecarbil on symptoms and health-related quality of life in patients with chronic heart failure: results from the COSMIC-HF study. Circulation: Heart Failure, 13, (doi: 10.1161/CIRCHEARTFAILURE.120.007814)
Ferreira, J. P., Docherty, K. F., Stienen, S., Jhund, P. S., Claggett, B. L., Solomon, S. D., Petrie, M. C., Gregsone, J., Pocock, S. L., Zannad, F., McMurray, J. (2020) Estimating the lifetime benefits of treatments for heart failure. JACC: Heart Failure, 8, pp. 984-995. (doi: 10.1016/j.jchf.2020.08.004)
Kristensen, S. L., Castagno, D., Shen, L., Jhund, P., Docherty, K., Rørth, R., Abraham, W. T., Desai, A., Dickstein, K., Rouleau, J. L., Zile, M. R., Swedberg, K., Packer, M., Solomon, S. D., Køber, L., McMurray, J. J.V. (2020) Prevalence and incidence of intra-ventricular conduction delays and outcomes in patients with heart failure and reduced ejection fraction: insights from PARADIGM‐HF and ATMOSPHERE. European Journal of Heart Failure, 22, pp. 2370-2379. (doi: 10.1002/ejhf.1972)
Brown, O., Costanzo, P., Clark, A. L., Condorelli, G., Cleland, J. G.F., Sathyapalan, T., Hepburn, D., Kilpatrick, E. S., Atkin, S. L. (2020) Relationship between a single measurement at baseline of body mass index, glycated hemoglobin, and the risk of mortality and cardiovascular morbidity in type 2 diabetes mellitus. Cardiovascular Endocrinology and Metabolism, 9, pp. 177-182. (doi: 10.1097/XCE.0000000000000202)
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Beazer, J. D., Patanapirunhakit, P., Gill, J. M.R., Graham, D., Karlsson, H., Ljunggren, S., Mulder, M., Freeman, D. J. (2020) High-density lipoprotein’s vascular protective functions in metabolic and cardiovascular disease - could extracellular vesicles be at play? Clinical Science, 134, pp. 2977-2986. (doi: 10.1042/CS20200892)
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2018
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Adamson, P. D., Hunter, A., Williams, M. C., Shah, A. S.V., McAllister, D. A., Pawade, T. A., Dweck, M. R., Mills, N. L., Berry, C., Boon, N. A., Clark, E., Flather, M., Forbes, J., McLean, S., Roditi, G., van Beek, E. J.R., Timmis, A. D., Newby, D. E. (2018) Diagnostic and prognostic benefits of computed tomography coronary angiography using the 2016 National Institute for Health and Care Excellence guidance within a randomised trial. Heart, 104, pp. 207-214. (doi: 10.1136/heartjnl-2017-311508)
Rørth, R., Fosbøl, E. L., Mogensen, U. M., Kragholm, K., Numé, A.-k., Gislason, G. H.,, Jhund, P. S., Petrie, M. C., McMurray, J. J.V., Torp-Pedersen, C., Køber, L., Kristensen, S. L. (2018) Employment status at time of first hospitalization for heart failure is associated with death and rehospitalization for heart failure. European Journal of Heart Failure, 20, pp. 240-247. (doi: 10.1002/ejhf.1046)
Adamson, P. D., Hunter, A., Madsen, D. M., Shah, A. S.V., McAllister, D. A., Pawade, T. A., Williams, M. C., Berry, C., Boon, N. A., Flather, M., Forbes, J., McLean, S., Roditi, G., Timmis, A. D., van Beek, E. J.R., Dweck, M. R., Mickley, H., Mills, N. L., Newby, D. E. (2018) High-sensitivity cardiac troponin I and the diagnosis of coronary artery disease in patients with suspected angina pectoris. Circulation: Cardiovascular Quality and Outcomes, 11, (doi: 10.1161/CIRCOUTCOMES.117.004227)
Ferguson, L.D., Ntuk, U.E., Celis-Morales, C., Mackay, D.F., Pell, J.P., Gill, J.M.R., Sattar, N. (2018) Men across a range of ethnicities have a higher prevalence of diabetes: findings from a cross-sectional study of 500000 UK Biobank participants. Diabetic Medicine, 35, pp. 270-276. (doi: 10.1111/dme.13551)
Cleland, J. G.F. (2018) Physicians Addicted to Prescribing Aspirin-a Disorder Of Cardiologists (PAPA-DOC) Syndrome: the headache of nonevidence-based medicine for ischemic heart disease? JACC: Heart Failure, 6, pp. 168-171. (doi: 10.1016/j.jchf.2017.11.014)
Platz, E., Jhund, P. S., Claggett, B. L., Pfeffer, M. A., Swedberg, K., Granger, C. B., Yusuf, S., Solomon, S. D., McMurray, J. J. (2018) Prevalence and prognostic importance of precipitating factors leading to heart failure hospitalization: recurrent hospitalizations and mortality. European Journal of Heart Failure, 20, pp. 295-303. (doi: 10.1002/ejhf.901)
Nikolaidou, T., Pellicori, P., Zhang, J., Kazmi, S., Goode, K. M., Cleland, J. G., Clark, A. L. (2018) Prevalence, predictors, and prognostic implications of PR interval prolongation in patients with heart failure. Clinical Research in Cardiology, 107, pp. 108-119. (doi: 10.1007/s00392-017-1162-6)
Welsh, P., Kou, L., Yu, C., Anand, I., van Veldhuisen, D. J., Maggioni, A. P., Desai, A. S., Solomon, S. D., Pfeffer, M. A., Cheng, S., Gullestad, L., Aukrust, P., Ueland, T., Swedberg, K., Young, J. B., Kattan, M. W., Sattar, N., McMurray, J. J.V. (2018) Prognostic importance of emerging cardiac, inflammatory, and renal biomarkers in chronic heart failure patients with reduced ejection fraction and anaemia: RED-HF study. European Journal of Heart Failure, 20, pp. 268-277. (doi: 10.1002/ejhf.988)
Emmens, J. E., Jones, D. J.L., Cao, T. H., Chan, D. C.S., Romaine, S. P.R., Quinn, P. A., Anker, S. D., Cleland, J. G., Dickstein, K., Filippatos, G., Hillege, H. L., Lang, C. C., Ponikowski, P., Samani, N. J., van Veldhuisen, D. J., Zannad, F., Zwinderman, A. H., Metra, M., de Boer, R. A., Voors, A. A., Ng, L. L. (2018) Proteomic diversity of high-density lipoprotein explains its association with clinical outcome in patients with heart failure. European Journal of Heart Failure, 20, pp. 260-267. (doi: 10.1002/ejhf.1101)
Anderson, J. J., Darwis, N. D.M., Mackay, D. F., Celis-Morales, C., Lyall, D. M., Sattar, N., Gill, J. M.R., Pell, J. P. (2018) Red and processed meat consumption and breast cancer: UK Biobank cohort study and meta-analysis. European Journal of Cancer, 90, pp. 73-82. (doi: 10.1016/j.ejca.2017.11.022)
Ford, T. J., Corcoran, D., Berry, C. (2018) Stable coronary syndromes: pathophysiology, diagnostic advances and therapeutic need. Heart, 104, pp. 284-292. (doi: 10.1136/heartjnl-2017-311446)
Cotter, G., Metra, M., Davison, B. A., Jondeau, G., Cleland, J. G.F., Bourge, R. C., Milo, O., O'Connor, C. M., Parker, J. D., Torre-Amione, G., van Veldhuisen, D. J., Kobrin, I., Rainisio, M., Senger, S., Edwards, C., McMurray, J. J.V., Teerlink, J. R. (2018) Systolic blood pressure reduction during the first 24 h in acute heart failure admission: friend or foe? European Journal of Heart Failure, 20, pp. 317-322. (doi: 10.1002/ejhf.889)
Stoumpos, S., Lees, J., Welsh, P., Hund, M., Geddes, C. C., Nelson, S. M., Mark, P. B. (2018) The utility of anti-Müllerian hormone in women with chronic kidney disease, on haemodialysis and after kidney transplantation. Reproductive BioMedicine Online, 36, pp. 219-226. (doi: 10.1016/j.rbmo.2017.11.003)
Ouwerkerk, W., Zwinderman, A. H., Ng, L. L., Demissei, B., Hillege, H. L., Zannad, F., van Veldhuisen, D. J., Samani, N. J., Ponikowski, P., Metra, M., ter Maaten, J. M., Lang, C. C., van der Harst, P., Filippatos, G., Dickstein, K., Cleland, J. G., Anker, S. D., Voors, A. A. (2018) Biomarker-guided versus guideline-based treatment of patients with heart failure: results from BIOSTAT-CHF. Journal of the American College of Cardiology, 71, pp. 386-398. (doi: 10.1016/j.jacc.2017.11.041)
Feldman, T., Mauri, L., Kahwash, R., Litwin, S., Ricciardi, M. J., van der Harst, P., Penicka, M., Fail, P. S., Kaye, D. M., Petrie, M. C., Basuray, A., Hummel, S. L., Forde-McLean, R., Nielsen, C. D., Lilly, S., Massaro, J. M., Burkhoff, D., Shah, S. J. (2018) Transcatheter interatrial shunt device for the treatment of heart failure with preserved ejection fraction (REDUCE LAP-HF I [Reduce Elevated Left Atrial Pressure in Patients With Heart Failure]): A phase 2, randomized, sham-controlled trial. Circulation, 137, pp. 364-375. (doi: 10.1161/CIRCULATIONAHA.117.032094)
Gale, C. R. et al. (2018) The epigenetic clock and objectively measured sedentary and walking behavior in older adults: the Lothian Birth Cohort 1936. Clinical Epigenetics, 10, (doi: 10.1186/s13148-017-0438-z)
Cleland, J. G.F., Flather, M. D., Altman, D. G., Kotecha, D. (2018) Reply: an incomplete story. Journal of the American College of Cardiology, 71, pp. 105. (doi: 10.1016/j.jacc.2017.10.078)
McCarroll, C. S. et al. (2018) Runx1 deficiency protects against adverse cardiac remodeling after myocardial infarction. Circulation, 137, pp. 57-70. (doi: 10.1161/CIRCULATIONAHA.117.028911)
Cleland, J. G.F., Bunting, K. V., Flather, M. D., Altman, D. G., Holmes, J., Coats, A. J.S., Manzano, L., McMurray, J. J.V., Ruschitzka, F., van Veldhuisen, D. J., von Lueder, T. G., Böhm, M., Andersson, B., Kjekshus, J., Packer, M., Rigby, A. S., Rosano, G., Wedel, H., Hjalmarson, Å., Wikstrand, J., Kotecha, D. (2018) Beta-blockers for heart failure with reduced, mid-range, and preserved ejection fraction: an individual patient-level analysis of double-blind randomized trials. European Heart Journal, 39, pp. 26-35. (doi: 10.1093/eurheartj/ehx564)
Kristensen, S. L., Mogensen, U. M., Tarnesby, G., Gimpelewicz, C. R., Ali, M. A., Shao, Q., Chiang, Y., Jhund, P. S., Abraham, W. T., Dickstein, K., McMurray, J. J.V., Køber, L. (2018) Aliskiren alone or in combination with enalapril vs. enalapril among patients with chronic heart failure with and without diabetes: a subgroup analysis from the ATMOSPHERE trial. European Journal of Heart Failure, 20, pp. 136-147. (doi: 10.1002/ejhf.896)
Pellicori, P., Urbinati, A., Zhang, J., Joseph, A. C., Costanzo, P., Lukaschuk, E., Capucci, A., Cleland, J. G.F., Clark, A. L. (2018) Clinical and prognostic relationships of pulmonary artery to aorta diameter ratio in patients with heart failure: a cardiac magnetic resonance imaging study. Clinical Cardiology, 41, pp. 20-27. (doi: 10.1002/clc.22840)
Patel, N., Hellmuth, C., Uhl, O., Godfrey, K., Briley, A., Welsh, P., Pasupathy, D., Seed, P., Koletzko, B., Poston, L. (2018) Cord metabolic profiles In obese pregnant women; insights into offspring growth and body composition. Journal of Clinical Endocrinology and Metabolism, 103, pp. 346-355. (doi: 10.1210/jc.2017-00876)
Rørth, R., Fosbøl, E. L., Mogensen, U. M., Kragholm, K., Jhund, P. S., Petrie, M. C., Schou, M., Gislason, G. H., McMurray, J. J.V., Torp-Pedersen, C., Køber, L., Kristensen, S. L. (2018) Evidence based therapy and its association with workforce detachment following first hospitalization for heart failure. JACC: Heart Failure, 6, pp. 41-48. (doi: 10.1016/j.jchf.2017.09.019)
Beggs, S. A.S., Jhund, P. S., Jackson, C. E., McMurray, J. J.V., Gardner, R. S. (2018) Non-ischaemic cardiomyopathy, sudden death and implantable defibrillators: a review and meta-analysis. Heart, 104, pp. 144-150. (doi: 10.1136/heartjnl-2016-310850)
Muilwijk, M., Celis-Morales, C., Nicolaou, M., Snijder, M. B., Gill, J. M.R., van Valkengoed, I. G.M. (2018) Plasma cholesteryl ester fatty acids do not mediate the association of ethnicity with type 2 diabetes: results from the HELIUS study. Molecular Nutrition and Food Research, 62, (doi: 10.1002/mnfr.201700528)
Maznyczka, A. M., McCartney, P., Berry, C. (2018) Reference invasive tests of microvascular injury in myocardial infarction. BMJ Open, 104, pp. 90-92. (doi: 10.1136/heartjnl-2017-311695)
Lee, M. M.Y. et al. (2018) Routine Non-invasive vs Invasive Management in Patients With Prior CABG With a NSTE-ACS: a Randomised Controlled Trial. (doi: 10.1136/heartjnl-2018-BCIS.9)
Souteyrand, G., Valladier, M., Amabile, N., Derimay, F., Harbaoui, B., Leddet, P., Barnay, P., Malcles, G., Mulliez, A., Berry, C., Eschalier, R., Combaret, N., Motreff, P. (2018) Diagnosis and management of spontaneously recanalized coronary thrombus guided by optical coherence tomography ― lessons from the French “Lotus Root” registry ― Circulation Journal, 82, pp. 783-790. (doi: 10.1253/circj.cj-17-0810)
Lachaud, Q., MacQuaide, N., Burton, F., Smith, G. (2018) High-throughput study of rabbit ventricle action potential populations in MI model. Biophysical Journal, 114, pp. 625A. (doi: 10.1016/j.bpj.2017.11.3377)
Berry, C., Carberry, J., Mangion, K. (2018) How to mend a broken heart? JACC: Cardiovascular Imaging, 11, pp. 420-422. (doi: 10.1016/j.jcmg.2017.02.017)
McAllister, D. A., Read, S., Kerssens, J., Livingstone, S., McGurnaghan, S., Jhund, P., Petrie, J., Sattar, N., Fischbacher, C., Kristensen, S. L., McMurray, J., Colhoun, H. M., Wild, S. (2018) Incidence of hospitalisation for heart failure and case-fatality among 3.25 million people with and without diabetes. Circulation, 138, pp. 2774-2785. (doi: 10.1161/CIRCULATIONAHA.118.034986)
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Layland, J., Tong, D., Lee, M., Berry, C. (2018) ST and T-Wave Abnormality as Footprint of Myocardial Oedema in Non–ST-Elevation Myocardial Infarction. (doi: 10.1016/j.hlc.2018.06.515)
Bouabdallaoui, N. et al. (2018) Society of Thoracic Surgeons risk score and EuroSCORE-2 appropriately assess 30-day postoperative mortality in the STICH trial and a contemporary cohort of patients with left ventricular dysfunction undergoing surgical revascularization. Circulation: Heart Failure, 11, (doi: 10.1161/circheartfailure.118.005531)
Delles, C., Carrick, E., Graham, D., Nicklin, S. A. (2018) Utilising proteomics to understand and define hypertension: where are we and where do we go? Expert Review of Proteomics, 15, pp. 581-592. (doi: 10.1080/14789450.2018.1493927)
2017
Avtaar Singh, S. S., Das De, S., Spadaccio, C., Berry, C., Al-Attar, N. (2017) An overview of different methods of myocardial protection currently employed peri-transplantation. Vessel Plus, 1, pp. 213-229. (doi: 10.20517/2574-1209.2017.26)
Van't Veer, M., Pijls, N. H.J., Hennigan, B., Watkins, S., Ali, Z. A., De Bruyne, B., Zimmermann, F. M., van Nunen, L. X., Barbato, E., Berry, C., Oldroyd, K. G. (2017) Comparison of different diastolic resting indexes to iFR: are they all equal? Journal of the American College of Cardiology, 70, pp. 3088-3096. (doi: 10.1016/j.jacc.2017.10.066)
Ford, T. J., Berry, C., De Bruyne, B., Yong, A. C.S., Barlis, P., Fearon, W. F., Ng, M. K.C. (2017) Physiological predictors of acute coronary syndromes: emerging insights from the plaque to the vulnerable patient. JACC: Cardiovascular Interventions, 10, pp. 2539-2547. (doi: 10.1016/j.jcin.2017.08.059)
Berry, C., McClure, J. D., Oldroyd, K. G. (2017) Meta-analysis of death and myocardial infarction in the DEFINE-FLAIR and iFR-SWEDEHEART trials: a hypothesis generating note of caution. Circulation, 136, pp. 2389-2391. (doi: 10.1161/CIRCULATIONAHA.117.030430)
Lei, C. L., Wang, K., Clerx, M., Johnstone, R. H., Hortigon-Vinagre, M. P., Zamora, V., Allan, A., Smith, G. L., Gavaghan, D. J., Mirams, G. R., Polonchuk, L. (2017) Tailoring mathematical models to stem-cell derived cardiomyocyte lines can improve predictions of drug-induced changes to their electrophysiology. Frontiers in Physiology, 8, (doi: 10.3389/fphys.2017.00986)
Dybus, A., Paul, L., Wyke, S., Brewster, S., Gill, J. M.R., Ramsay, A., Campbell, E. (2017) Validation of smartphone step count algorithm used in STARFISH smartphone application. Technology and Health Care, 25, pp. 1157-1162. (doi: 10.3233/thc-170970)
Duncan, G., Firth, K., George, V., Hoang, M. D., Staniforth, A., Smith, G., Denning, C. (2017) Drug-mediated shortening of action potentials in LQTS2 human induced pluripotent stem cell-derived cardiomyocytes. Stem Cells and Development, 26, pp. 1695-1705. (doi: 10.1089/scd.2017.0172)
Celis-Morales, C. A., Petermann, F., Hui, L., Lyall, D. M., Iliodromiti, S., McLaren, J., Anderson, J., Welsh, P., Mackay, D. F., Pell, J. P., Sattar, N., Gill, J. M.R., Gray, S. R. (2017) Associations between diabetes and both cardiovascular disease and all-cause mortality are modified by grip strength: evidence from UK Biobank, a prospective population-based cohort study. Diabetes Care, 40, pp. 1710-1718. (doi: 10.2337/dc17-0921)
Kaye, D. M., Silvestry, F. E., Gustafsson, F., Cleland, J. G., van Veldhuisen, D. J., Ponikowski, P., Komtebedde, J., Nanayakkara, S., Burkhoff, D., Shah, S. J. (2017) Impact of atrial fibrillation on rest and exercise haemodynamics in heart failure with mid-range and preserved ejection fraction. European Journal of Heart Failure, 19, pp. 1690-1697. (doi: 10.1002/ejhf.930)
Hilfiker-Kleiner, D., Haghikia, A., Masuko, D., Nonhoff, J., Held, D., Libhaber, E., Petrie, M. C., Walker, N. L., Podewski, E., Berliner, D., Bauersachs, J., Sliwa, K. (2017) Outcome of subsequent pregnancies in patients with a history of peripartum cardiomyopathy. European Journal of Heart Failure, 19, pp. 1723-1728. (doi: 10.1002/ejhf.808)
Carberry, J., Carrick, D., Haig, C., Ahmed, N., Mordi, I., McEntegart, M., Petrie, M. C., Eteiba, H., Hood, S., Watkins, S., Lindsay, M., Davie, A., Mahrous, A., Ford, I., Sattar, N., Welsh, P., Radjenovic, A., Oldroyd, K. G., Berry, C. (2017) Persistence of infarct zone T2 hyperintensity at 6 months after acute ST-elevation myocardial infarction: incidence, pathophysiology and prognostic implications. Circulation: Cardiovascular Imaging, 10, (doi: 10.1161/CIRCIMAGING.117.006586)
Kristensen, S. L., Jhund, P. S., Lee, M. M.Y., Køber, L., Solomon, S. D., Granger, C. B., Yusuf, S., Pfeffer, M. A., Swedberg, K., McMurray, J. J.V. (2017) Prevalence of prediabetes and undiagnosed diabetes in patients with HFpEF and HFrEF and associated clinical outcomes. Cardiovascular Drugs and Therapy, 31, pp. 545-549. (doi: 10.1007/s10557-017-6754-x)
O'Neill, D.G., Riddell, A., Church, D.B., Owen, L., Brodbelt, D.C., Hall, J.L. (2017) Urinary incontinence in bitches under primary veterinary care in England: prevalence and risk factors. Journal of Small Animal Practice, 58, pp. 685-693. (doi: 10.1111/jsap.12731)
Yates, T., Zaccardi, F., Dhalwani, N. N., Davies, M. J., Bakrania, K., Celis-Morales, C. A., Gill, J. M.R., Franks, P. W., Khunti, K. (2017) Association of walking pace and handgrip strength with all-cause, cardiovascular, and cancer mortality: a UK biobank observational study. European Heart Journal, 38, pp. 3232-3240. (doi: 10.1093/eurheartj/ehx449)
Wang, G., Durussel, J., Shurlock, J., Mooses, M., Fuku, N., Bruinvels, G., Pedlar, C., Burden, R., Murray, A., Yee, B., Keenan, A., McClure, J. D., Sottas, P.-E., Pitsiladis, Y. P. (2017) Validation of whole-blood transcriptome signature during microdose recombinant human erythropoietin (rHuEpo) administration. BMC Genomics, 18, (doi: 10.1186/s12864-017-4191-7)
Krochmal, M., Kontostathi, G., Magalhães, P., Makridakis, M., Klein, J., Husi, H., Leierer, J., Mayer, G., Bascands, J.-L., Denis, C., Zoidakis, J., Zürbig, P., Delles, C., Schanstra, J. P., Mischak, H., Vlahou, A. (2017) Urinary peptidomics analysis reveals proteases involved in diabetic nephropathy. Scientific Reports, 7, (doi: 10.1038/s41598-017-15359-9)
Vieira, M. C., White, S. L., Patel, N., Seed, P. T., Briley, A. L., Sandall, J., Welsh, P., Sattar, N., Nelson, S. M., Lawlor, D. A., Poston, L., Pasupathy, D. (2017) Prediction of uncomplicated pregnancies in obese women: a prospective multicentre study. BMC Medicine, 15, (doi: 10.1186/s12916-017-0956-8)
Sartini, C., Whincup, P. H., Wannamethee, S. G., Jefferis, B. J., Lennon, L., Lowe, G. D.O., Welsh, P., Sattar, N., Morris, R. W. (2017) Associations of time of day with cardiovascular disease risk factors measured in older men: results from the British Regional Heart Study. BMJ Open, 7, (doi: 10.1136/bmjopen-2017-018264)
Shah, P., Pellicori, P., Macnamara, A., Urbinati, A., Clark, A. L. (2017) Is swimming safe in heart failure? A systematic review. Cardiology in Review, 25, pp. 321-325. (doi: 10.1097/CRD.0000000000000154)
Shen, L., Ramires, F., Martinez, F., Bodanese, L. C., Echeverría, L. E., Gómez, E. a., Abraham, W. t., Dickstein, K., Køber, L., Packer, M., Rouleau, J. L., Solomon, S. D., Swedberg, K., Zile, M. R., Jhund, P. S., Gimpelewicz, C. R., McMurray, J. J.V. (2017) Contemporary characteristics and outcomes in chagasic heart failure compared with other nonischemic and ischemic cardiomyopathy. Circulation: Heart Failure, 10, (doi: 10.1161/CIRCHEARTFAILURE.117.004361)
Mary, S., Kulkarni, M. J., Mehendale, S. S., Joshi, S. R., Giri, A. P. (2017) Differential accumulation of vimentin fragments in preeclamptic placenta. Cytoskeleton, 74, pp. 420-425. (doi: 10.1002/cm.21390)
Holman, R. R., Coleman, R. L., Chan, J. C. N., Chiasson, J.-L., Feng, H., Ge, J., Gerstein, H. C., Gray, R., Huo, Y., Lang, Z., McMurray, J. J., Rydén, L., Schröder, S., Sun, Y., Theodorakis, M. J., Tendera, M., Tucker, L., Tuomilehto, J., Wei, Y., Yang, W., Wang, D., Hu, D., Pan, C., ACE Study Group, (2017) Effects of acarbose on cardiovascular and diabetes outcomes in patients with coronary heart disease and impaired glucose tolerance (ACE): a randomised, double-blind, placebo-controlled trial. Lancet Diabetes and Endocrinology, 5, pp. 877-886. (doi: 10.1016/S2213-8587(17)30309-1)
Wong, C. M., Hawkins, N. M., Ezekowitz, J. A., Jhund, P. S., Savu, A., MacDonald, M. R., Kristensen, S. L., Petrie, M. C., McMurray, J. J.V., McAlister, F. A., Kaul, P. (2017) Heart failure in young adults is associated with high mortality: a contemporary population-level analysis. Canadian Journal of Cardiology, 33, pp. 1472-1477. (doi: 10.1016/j.cjca.2017.05.009)
Pontillo, C. et al. (2017) Prediction of chronic kidney disease stage 3 by CKD273, a urinary proteomic biomarker. Kidney International Reports, 2, pp. 1066-1075. (doi: 10.1016/j.ekir.2017.06.004)
Welsh, P., Grassia, G., Botha, S., Sattar, N., Maffia, P. (2017) Targeting inflammation to reduce cardiovascular disease risk: a realistic clinical prospect? British Journal of Pharmacology, 174, pp. 3898-3913. (doi: 10.1111/bph.13818)
Schmieder, R. E., Wagner, F., Mayr, M., Delles, C., Ott, C., Keicher, C., Hrabak-Paar, M., Heye, T., Aichner, S., Khder, Y., Yates, D., Albrecht, D., Langenickel, T., Freyhardt, P., Janka, R., Bremerich, J. (2017) The effect of sacubitril/valsartan compared to olmesartan on cardiovascular remodelling in subjects with essential hypertension: the results of a randomized, double-blind, active-controlled study. European Heart Journal, 38, pp. 3308-3317. (doi: 10.1093/eurheartj/ehx525)
Mogensen, U. M., Jhund, P. S., Abraham, W. T., Desai, A. S., Dickstein, K., Packer, M., Rouleau, J. L., Solomon, S. D., Swedberg, K., Zile, M. R., Køber, L., McMurray, J. J.V. (2017) Type of atrial fibrillation and clinical outcomes in patients with heart failure and reduced ejection fraction. Journal of the American College of Cardiology, 70, pp. 2490-2500. (doi: 10.1016/j.jacc.2017.09.027)
Rutherford, E., Mangion, K., Mccomb, C., Bell, E., Cockburn, S., Talle, M., Roditi, G., Welsh, P., Woodward, R., Radjenovic, A., Struthers, A. D., Jardine, A., Berry, C., Patel, R. K., Mark, P. B. (2017) Myocardial changes in incident haemodialysis patients over 6-months: an observational cardiac magnetic resonance imaging study. Scientific Reports, 7, (doi: 10.1038/s41598-017-14481-y)
Kobayashi, Y., Johnson, N. P., Zimmermann, F. M., Witt, N., Berry, C., Jeremias, A., Koo, B.-K., Esposito, G., Rioufol, G., Park, S.-J., Nishi, T., Choi, D.-H., Oldroyd, K. G., Barbato, E., Pijls, N. H. J., De Bruyne, B., Fearon, W. F. (2017) Agreement of the resting distal to aortic coronary pressure with the instantaneous wave-free ratio. Journal of the American College of Cardiology, 70, pp. 2105-2113. (doi: 10.1016/j.jacc.2017.08.049)
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Wilson, R., Aung, H., Ju, X., Paterson, C., Sayer, R., McIntyre, A., Going, J., Irvine, R., Berry, C. (2016) Optical coherence tomography: an experimental validation for vascular imaging of saphenous vein bypass grafts. Biomedical Physics and Engineering Express, 2, (doi: 10.1088/2057-1976/2/2/025002)
Cuba Gyllensten, I., Bonomi, A. G., Goode, K. M., Reiter, H., Habetha, J., Amft, O., Cleland, J. G.F. (2016) Early indication of decompensated heart failure in patients on home-telemonitoring: a comparison of prediction algorithms based on daily weight and noninvasive transthoracic bio-impedance. JMIR Medical Informatics, 4, (doi: 10.2196/medinform.4842)
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Currie, G., Delles, C., Touyz, R. M., Staessen, J. A., Dominiczak, A. F., Jennings, G. L. R., Wang, J.-G. (2016) A woman with treatment-resistant hypertension. Hypertension, 67, pp. 243-250. (doi: 10.1161/HYPERTENSIONAHA.115.06756)
Bhandari, S., Ives, N., Brettell, E. A., Valente, M., Cockwell, P., Topham, P. S., Cleland, J. G.F., Khwaja, A., El Nahas, M. (2016) Multicentre randomized controlled trial of angiotensin-converting enzyme inhibitor/angiotensin receptor blocker withdrawal in advanced renal disease: the STOP-ACEi trial. Nephrology Dialysis Transplantation, 31, pp. 255-261. (doi: 10.1093/ndt/gfv346)
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Small, H. Y., Currie, G. E., Delles, C. (2016) Prostasin, proteases, and preeclampsia. Journal of Hypertension, 34, pp. 193-195. (doi: 10.1097/hjh.0000000000000828)
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Watt, J., Kennedy, S., Ahmed, N., Hayhurst, J., McClure, J. D., Berry, C., Wadsworth, R. M., Oldroyd, K. G. (2016) The relationship between oxidised LDL, endothelial progenitor cells and coronary endothelial function in patients with CHD. Open Heart, 3, (doi: 10.1136/openhrt-2015-000342)
Mangion, K., Gao, H., Radjenovic, A., Luo, X., Haig, C., Berry, C. (2016) Pixel-tracking derived strain using the GlasgowHeart Method. Journal of Cardiovascular Magnetic Resonance, 18, (doi: 10.1186/1532-429X-18-S1-P9)
Bruno, N., ter Maaten, J. M., Ovchinnikova, E. S., Vegter, E. L., Valente, M. A.E., van der Meer, P., de Boer, R. A., van der Harst, P., Schmitter, D., Metra, M., O'Connor, C. M., Ponikowski, P., Teerlink, J. R., Cotter, G., Davison, B., Cleland, J. G.F., Givertz, M. M., Bloomfield, D. M., Dittrich, H. C., Pinto, Y. M., van Veldhuisen, D. J., Hillege, H. L., Berezikov, E., Voors, A. A. (2016) MicroRNAs relate to early worsening of renal function in patients with acute heart failure. International Journal of Cardiology, 203, pp. 564-569. (doi: 10.1016/j.ijcard.2015.10.217)
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Zhang, J., Hobkirk, J., Carroll, S., Pellicori, P., Clark, A. L., Cleland, J. G.F. (2016) Exploring quality of life in patients with and without heart failure. International Journal of Cardiology, 202, pp. 676-684. (doi: 10.1016/j.ijcard.2015.09.076)
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Cowie, M. R., Bax, J., Bruining, N., Cleland, J. G.F., Koehler, F., Malik, M., Pinto, F., van der Velde, E., Vardas, P. (2016) e-Health: a position statement of the European Society of Cardiology. European Heart Journal, 37, pp. 63-66. (doi: 10.1093/eurheartj/ehv416)
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Platz, E., Lewis, E. F., Uno, H., Peck, J., Pivetta, E., Merz, A. A., Hempel, D., Wilson, C., Frasure, S. E., Jhund, P. S., Cheng, S., Solomon, S. D. (2016) Detection and prognostic value of pulmonary congestion by lung ultrasound in ambulatory heart failure patients. European Heart Journal, 37, pp. 1244-1251. (doi: 10.1093/eurheartj/ehv745)
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McCallum, J. E., Mackenzie, A. E., Divorty, N., Clarke, C., Delles, C., Milligan, G., Nicklin, S. A. (2016) G protein-coupled receptor 35 mediates human saphenous vein vascular smooth muscle cell migration and endothelial cell proliferation. Journal of Vascular Research, 52, pp. 383-395. (doi: 10.1159/000444754)
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Carrick, D., Haig, C., Watkins, S., Ahmed, N., McEntegart, M., Petrie, M. C., Eteiba, H., Hood, S., Watkins, S., Lindsay, M. M., Davie, A., Mahrous, A., Mordi, I., Rauhalammi, S., Sattar, N., Welsh, P., Radjenovic, A., Ford, I., Oldroyd, K., Berry, C. (2016) Myocardial hemorrhage after acute reperfused ST-segment-elevation myocardial infarction. Circulation: Cardiovascular Imaging, 9, (doi: 10.1161/CIRCIMAGING.115.004148)
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O'Donovan, G., Bakrania, K., Ghouri, N., Yates, T., Gray, L. J., Hamer, M., Stamatakis, E., Khunti, K., Davies, M., Sattar, N., Gill, J. M.R. (2016) Non-exercise equations to estimate fitness in white European and South Asian men. Medicine and Science in Sports and Exercise, 48, pp. 854-859. (doi: 10.1249/MSS.0000000000000836)
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2015
Cameron, A. C., Touyz, R. M., Lang, N. N. (2015) Vascular complications of cancer chemotherapy. Canadian Journal of Cardiology, 32, pp. 852-862. (doi: 10.1016/j.cjca.2015.12.023)
Cleland, J. G.F., Mareev, Y. (2015) CRT for heart failure and ESRD: more trials or more thought needed? Journal of the American College of Cardiology, 66, pp. 2630-2632. (doi: 10.1016/j.jacc.2015.10.022)
Henson, J., Davies, M. J., Bodicoat, D. H., Edwardson, C. L., Gill, J. M.R., Stensel, D. J., Tolfrey, K., Dunstan, D. W., Khunti, K., Yates, T. (2015) Breaking up prolonged sitting with standing or walking attenuates the postprandial metabolic response in postmenopausal women: a randomized acute study. Diabetes Care, (doi: 10.2337/dc15-1240)
Berry, C., Corcoran, D., Hennigan, B., Watkins, S., Layland, J., Oldroyd, K. G. (2015) Fractional flow reserve-guided management in stable coronary disease and acute myocardial infarction: recent developments. European Heart Journal, 36, pp. 3155-3164. (doi: 10.1093/eurheartj/ehv206)
Nam, J., Briggs, A., Layland, J., Oldroyd, K. G., Curzen, N., Sood, A., Balachandran, K., Das, R., Junejo, S., Eteiba, H., Petrie, M. C., Lindsay, M., Watkins, S., Corbett, S., O'Rourke, B., O'Donnell, A., Stewart, A., Hannah, A., McConnachie, A., Henderson, R., Berry, C. (2015) Fractional flow reserve (FFR) versus angiography in guiding management to optimise outcomes in non-ST segment elevation myocardial infarction (FAMOUS-NSTEMI) developmental trial: cost-effectiveness using a mixed trial- and model-based methods. Cost Effectiveness and Resource Allocation, 2015, (doi: 10.1186/s12962-015-0045-9)
Gao, H., Li, W.G., Cai, L., Berry, C., Luo, X.Y. (2015) Parameter estimation in a Holzapfel–Ogden law for healthy myocardium. Journal of Engineering Mathematics, 95, pp. 231-248. (doi: 10.1007/s10665-014-9740-3)
Sattar, N., Gill, J. M.R. (2015) Type 2 diabetes in migrant south Asians: mechanisms, mitigation, and management. Lancet Diabetes and Endocrinology, 3, pp. 1004-1016. (doi: 10.1016/S2213-8587(15)00326-5)
Zinman, B., Wanner, C., Lachin, J. M., Fitchett, D., Bluhmki, E., Hantel, S., Mattheus, M., Devins, T., Johansen, O. E., Woerle, H. J., Broedl, U. C., Inzucchi, S. E., EMPA-REG OUTCOME Investigators, (2015) Empagliflozin, cardiovascular outcomes, and mortality in type 2 diabetes. New England Journal of Medicine, 373, pp. 2117-2128. (doi: 10.1056/NEJMoa1504720)
Layland, J., Nerlekar, N., Palmer, S., Berry, C., Oldroyd, K. (2015) Invasive assessment of the coronary microcirculation in the catheter laboratory. International Journal of Cardiology, 199, pp. 141-149. (doi: 10.1016/j.ijcard.2015.05.190)
Simpson, J., Jhund, P. S., Silva Cardoso, J., Martinez, F., Mosterd, A., Ramires, F., Rizkala, A. R., Senni, M., Squire, I., Gong, J., Lefkowitz, M. P., Shi, V. C., Desai, A. S., Rouleau, J. L., Swedberg, K., Zile, M. R., McMurray, J. J.V., Packer, M., Solomon, S. D. (2015) Comparing LCZ696 with Enalapril according to baseline risk using the MAGGIC and EMPHASIS-HF risk scores. Journal of the American College of Cardiology, 66, pp. 2059-2071. (doi: 10.1016/j.jacc.2015.08.878)
Jolicœur, E. M., Dunning, A., Castelvecchio, S., Dabrowski, R., Waclawiw, M. A., Petrie, M. C., Stewart, R., Jhund, P. S., Desvigne-Nickens, P., Panza, J. A., Bonow, R. O., Sun, B., San, T. R., Al-Khalidi, H. R., Rouleau, J. L., Velazquez, E. J., Cleland, J. G.F. (2015) Importance of angina in patients with coronary disease, heart failure, and left ventricular systolic dysfunction. Journal of the American College of Cardiology, 66, pp. 2092-2100. (doi: 10.1016/j.jacc.2015.08.882)
Aitken, E., Kerr, D., Geddes, C., Berry, C., Kingsmore, D. (2015) Cardiovascular changes occurring with occlusion of a mature arteriovenous fistula. Journal of Vascular Access, 16, pp. 459-466. (doi: 10.5301/jva.5000336)
Cameron, A. C., Mccallum, L., Gardiner, T., Darroch, C., Walters, M. R., Oldroyd, K. G. (2015) Impact of treatment algorithms on the prescribing of antithrombotic therapy in patients with suspected acute coronary syndrome - a prospective audit. British Journal of Clinical Pharmacology, 80, pp. 1176-1184. (doi: 10.1111/bcp.12714)
Simpson, J., Castagno, D., Doughty, R. N., Poppe, K. K., Earle, N., Squire, I., Richards, M., Andersson, B., Ezekowitz, J. A., Komajda, M., Petrie, M. C., McAlister, F. A., Gamble, G. D., Whalley, G. A., McMurray, J. J.V. (2015) Is heart rate a risk marker in patients with chronic heart failure and concomitant atrial fibrillation? Results from the MAGGIC meta-analysis. European Journal of Heart Failure, 17, pp. 1182-1191. (doi: 10.1002/ejhf.346)
Pellicori, P., Joseph, A. C., Zhang, J., Lukaschuk, E., Sherwi, N., Bourantas, C. V., Loh, H., Clark, A. L., Cleland, J. G.F. (2015) The relationship of QRS morphology with cardiac structure and function in patients with heart failure. Clinical Research in Cardiology, 104, pp. 935-945. (doi: 10.1007/s00392-015-0861-0)
Inglis, S. C., Clark, R. A., Dierckx, R., Prieto-Merino, D., Cleland, J. G.F. (2015) Structured telephone support or non-invasive telemonitoring for patients with heart failure. Cochrane Database of Systematic Reviews, 2015, (doi: 10.1002/14651858.CD007228.pub3)
Deng, L., Blanco Lopez, F. J., Stevens, H., Lu, R., Caudrillier, A., McBride, M., McClure, J. D., Grant, J., Thomas, M., Frid, M., Stenmark, K., White, K., Seto, A. G., Morrell, N. W., Bradshaw, A. C., MacLean, M. R., Baker, A. H. (2015) MicroRNA-143 activation regulates smooth muscle and endothelial cell crosstalk in pulmonary arterial hypertension. Circulation Research, 117, pp. 870-883. (doi: 10.1161/CIRCRESAHA.115.306806)
Jhund, P., Fu, M., Bayram, E., Chen, C.-H., Negrusz-Kawecka, M., Rosenthal, A., Desai, A. S., Lefkowitz, M. P., Rizkala, A. R., Rouleau, J. L., Shi, V. C., Solomon, S. D., Swedberg, K., Zile, M. R., McMurray, J. J.V., Packer, M. (2015) Efficacy and safety of LCZ696 (sacubitril-valsartan) according to age: insights from PARADIGM-HF. European Heart Journal, 36, pp. 2576-2584. (doi: 10.1093/eurheartj/ehv330)
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Skogstrand, T., Leh, S., McClure, J., Dashti, M., Iversen, B. M., Graham, D., McBride, M., Hultström, M. (2015) Identification of a common molecular pathway in hypertensive renal damage. Journal of Hypertension, 33, pp. 584-596. (doi: 10.1097/HJH.0000000000000395)
Pellicori, P., Cleland, J. G.F. (2015) Is the epidemic of heart disease really over or just evolving? American Journal of Medicine, 128, pp. e17. (doi: 10.1016/j.amjmed.2014.09.018)
Campbell, R. T., Jackson, C., Wright, A., Gardner, R. S., Ford, I., Davidson, P. M., Denvir, M. A., Hogg, K. J., Johnson, M. J., Petrie, M. C., McMurray, J. J. V. (2015) Palliative care needs in patients hospitalized with heart failure (PCHF) study: rationale and design. ESC Heart Failure, 2, pp. 25-36. (doi: 10.1002/ehf2.12027)
Dierckx, R., Cleland, J. G.F., Parsons, S., Putzu, P., Pellicori, P., Dicken, B., Boyalla, V., Clark, A. L. (2015) Prescribing patterns to optimize heart rate: analysis of 1,000 consecutive outpatient appointments to a single heart failure clinic over a 6-month period. JACC: Heart Failure, 3, pp. 224-230. (doi: 10.1016/j.jchf.2014.11.003)
Khand, A. U., Chew, P. G., Douglas, H., Jones, J., Jan, A., Cleland, J.G.F. (2015) The effect of carvedilol on b-type natriuretic peptide and cardiac function in patients with heart failure and persistent atrial fibrillation. Cardiology, 130, pp. 153-158. (doi: 10.1159/000368746)
Pellicori, P., Cleland, J. G.F. (2015) Update on management of heart failure with preserved ejection fraction. Current Opinion in Cardiology, 30, pp. 173-178. (doi: 10.1097/HCO.0000000000000152)
McManus, F., Fraser, R., Davies, E., Connell, J.M.C., Freel, E.M. (2015) Plasma steroid profiling and response to trophins to illustrate intra-adrenal dynamics. Journal of Endocrinology, 224, pp. 149-157. (doi: 10.1530/JOE-14-0561)
Badar, A. A., Perez-Moreno, A. C., Hawkins, N. M., Brunton, A. P.T., Jhund, P. S., Wong, C. M., Solomon, S. D., Granger, C. B., Yusuf, S., Pfeffer, M. A., Swedberg, K., Gardner, R. S., Petrie, M. C., McMurray, J. J.V. (2015) Clinical characteristics and outcomes of patients with angina and heart failure in the CHARM (Candesartan in Heart Failure Assessment of Reduction in Mortality and Morbidity) programme. European Journal of Heart Failure, 17, pp. 196-204. (doi: 10.1002/ejhf.221)
Kristensen, S. L., Jhund, P. S., Køber, L., Preiss, D., Kjekshus, J., McKelvie, R. S., Zile, M. R., Anand, I. S., Wikstrand, J. G.F., Wedel, H., Komajda, M., Carson, P. E., Cleland, J., McMurray, J. J.V. (2015) Comparison of outcomes after hospitalization for worsening heart failure, myocardial infarction, and stroke in patients with heart failure and reduced and preserved ejection fraction. European Journal of Heart Failure, 17, pp. 169-176. (doi: 10.1002/ejhf.211)
Boyalla, V., Putzu, P., Dierckx, R., Clark, A. L., Pellicori, P. (2015) Patent Ductus Arteriosus in older adults: incidental finding or relevant pathology? Journal of the American Geriatrics Society, 63, pp. 409-411. (doi: 10.1111/jgs.13256)
Layland, J. et al. (2015) Fractional flow reserve vs. angiography in guiding management to optimize outcomes in non-ST-segment elevation myocardial infarction: the British Heart Foundation FAMOUS-NSTEMI randomized trial. European Heart Journal, 36, pp. 100-111. (doi: 10.1093/eurheartj/ehu338)
Ghouri, I. A., Kelly, A., Burton, F. L., Smith, G. L., Kemi, O. J. (2015) 2-photon excitation fluorescence microscopy enables deeper high-resolution imaging of voltage and Ca2+in intact mice, rat, and rabbit hearts. Journal of Biophotonics, 8, pp. 112-123. (doi: 10.1002/jbio.201300109)
Metra, M., Mentz, R. J., Chiswell, K., Bloomfield, D. M., Cleland, J. G.F., Cotter, G., Davison, B. A., Dittrich, H. C., Fiuzat, M., Givertz, M. M., Lazzarini, V., Mansoor, G. A., Massie, B. M., Ponikowski, P., Teerlink, J. R., Voors, A. A., O'Connor, C. M. (2015) Acute heart failure in elderly patients: worse outcomes and differential utility of standard prognostic variables. Insights from the PROTECT trial. European Journal of Heart Failure, 17, pp. 109-118. (doi: 10.1002/ejhf.207)
Malkova, D., Gill, J. M.R., Manthou, E. (2015) Effect of exercise programmes with aerobic exercise sessions of similar intensity but different frequency and duration on health related measures in overweight women. Journal of Physical Activity and Health, 12, pp. 80-86. (doi: 10.1123/jpah.2013-0047)
Dickstein, K., Normand, C., Anker, S.D., Auricchio, A., Lundqvist Blomstrom, C., Bogale, N., Cleland, J., Filippatos, G., Gasparini, M., Gitt, A., Hindricks, G., Kuck, K.-H., Ponikowski, P., Stellbrink, C., Ruschitzka, F., Linde, C. (2015) European cardiac resynchronization therapy survey II: rationale and design. Europace, 17, pp. 137-141. (doi: 10.1093/europace/euu312)
Kristensen, S. L. L., Køber, L., Jhund, P. S., Solomon, S. D., Kjekshus, J., McKelvie, R. S., Zile, M. R., Granger, C. B., Wikstrand, J., Komajda, M., Carson, P. E., Pfeffer, M. A., Swedberg, K., Wedel, H., Yusuf, S., McMurray, J. J. V. (2015) International geographic variation in event rates in trials of heart failure with preserved and reduced ejection fraction. Circulation, 131, pp. 43-53. (doi: 10.1161/CIRCULATIONAHA.114.012284)
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Ripley, D. P., Brown, J., Everett, C. C., Bijsterveld, P., Walker, S., Sculpher, M., McCann, G. P., Berry, C., Plein, S., Greenwood, J. P. (2015) Rationale and design of the Clinical Evaluation of Magnetic Resonance Imaging in Coronary heart disease 2 trial (CE-MARC 2): a prospective, multicenter, randomized trial of diagnostic strategies in suspected coronary heart disease. American Heart Journal, 169, pp. 17-24.e1. (doi: 10.1016/j.ahj.2014.10.008)
Dierckx, R., Pellicori, P., Cleland, J.G.F., Clark, A.L. (2015) Telemonitoring in heart failure: Big Brother watching over you. Heart Failure Reviews, 20, pp. 107-116. (doi: 10.1007/s10741-014-9449-4)
Layland, J., Rauhalammi, S., Watkins, S., Ahmed, N., McClure, J., Lee, M. M.Y., Carrick, D., O’Donnell, A., Sood, A., Petrie, M. C., Teng Yue May, V., Eteiba, H., Lindsay, M., McEntegart, M., Oldroyd, K. G., Radjenovic, A., Berry, C. (2015) Assessment of fractional flow reserve in patients with recent Non–ST-Segment–Elevation Myocardial Infarction. Circulation: Cardiovascular Interventions, 8, (doi: 10.1161/circinterventions.114.002207)
Musunuru, K., Hickey, K. T., Al-Khatib, S. M., Delles, C., Fornage, M., Fox, C. S., Frazier, L., Gelb, B. D., Herrington, D. M., Lanfear, D. E., Rosand, J. (2015) Basic concepts and potential applications of genetics and genomics for cardiovascular and stroke clinicians: a scientific statement from the American Heart Association. Circulation: Cardiovascular Genetics, 8, pp. 216-242. (doi: 10.1161/HCG.0000000000000020)
Pellicori, P., Costanzo, P. (2015) Betabloccanti in pazienti con scompenso cardiaco e fibrillazione atriale = [Betablockers in patients with heart failure and atrial fibrillation] Giornale italiano di cardiologia, 16, pp. 613-616. (doi: 10.1714/2066.22428)
Welsh, P., Preiss, D., Touyz, R. M. (2015) Biomarkers of hypertension and cardiovascular disease. Royal Society of Chemistry
Welsh, P., Preiss, D., Tsiropoulou, S., Rios, F. J., Harvey, A., Dulak-Lis, M. G., Montezano, A. C., Touyz, R. M. (2015) Biomarkers of vascular inflammation and cardiovascular disease. Springer
Newby, D. et al. (2015) CT coronary angiography in patients with suspected angina due to coronary heart disease (SCOT-HEART): an open-label, parallel-group, multicentre trial. Lancet, 385, pp. 2383-2391. (doi: 10.1016/S0140-6736(15)60291-4)
Badar, A. A., Perez-Moreno, A. C., Hawkins, N. M., Jhund, P. S., Brunton, A. P.T., Anand, I. S., McKelvie, R. S., Komajda, M., Zile, M. R., Carson, P. E., Gardner, R. S., Petrie, M. C., McMurray, J. J.V. (2015) Clinical characteristics and outcomes of patients with coronary artery disease and angina. Circulation: Heart Failure, 8, pp. 717-724. (doi: 10.1161/CIRCHEARTFAILURE.114.002024)
Corcoran, D., Berry, C., Oldroyd, K. (2015) Current frontiers in the clinical research of coronary physiology. Interventional Cardiology, 7, pp. 97-106.
Campbell, R. T., Jhund, P. S., Dalzell, J. R., Cannon, J., Mordi, I., Sonecki, P., Tzemos, N. (2015) Diagnosis and resolution of loeffler endocarditis secondary to eosinphilic granulomatosis with polyangiitis demonstrated by cardiac magnetic resonance-t2 mapping. Circulation, 131, pp. 114-117. (doi: 10.1161/CIRCULATIONAHA.114.011291)
Pellicori, P., Kaur, K., Clark, A. L. (2015) Fluid management in patients with chronic heart failure. Cardiac Failure Review, 1, pp. 90-95. (doi: 10.15420/cfr.2015.1.2.90)
Gao, H., Qi, N., Ma, X., Griffith, B. E., Berry, C., Luo, X. (2015) Fluid-structure interaction model of human mitral valve within left ventricle. Springer International Publishing
Lopez, L. M., Hill, W. D., Harris, S. E., Valdes Hernandez, M., Munoz Maniega, S., Bastin, M. E., Bailey, E., Smith, C., McBride, M., McClure, J., Graham, D., Dominiczak, A., Yang, Q., Fornage, M., Ikram, M. A., Debette, S., Launer, L., Bis, J. C., Schmidt, R., Seshadri, S., Porteous, D. J., Starr, J., Deary, I. J., Wardlaw, J. M. (2015) Genes from a translational analysis support a multifactorial nature of white matter hyperintensities. Stroke, 46, pp. 341-347. (doi: 10.1161/STROKEAHA.114.007649)
Mistry, H.D., Eisele, N., Escher, G., Dick, B., Surbek, D., Delles, C., Currie, G., Schlembach, D., Mohaupt, M.G., Gennari-Moser, C. (2015) Gestation-specific reference intervals for comprehensive spot urinary steroid hormone metabolite analysis in normal singleton pregnancy and 6 weeks postpartum. Reproductive Biology and Endocrinology, 13, (doi: 10.1186/s12958-015-0100-6)
Ferguson, L.D., Logue, J. (2015) Has IMPROVE-IT improved cardiovascular outcome? Journal of the Royal College of Physicians of Edinburgh, 45, pp. 215-217.
Jhund, P. S. (2015) Heart failure management: continuing to fail or signs of success? Cardiovascular Drugs and Therapy, 29, pp. 5-6. (doi: 10.1007/s10557-015-6574-9)
Gao, H., Berry, C., Luo, X. (2015) Image-derived human left ventricular modelling with fluid-structure interaction. Springer International Publishing
Aitken, E., Geddes, C., Thomson, P., Kasthuri, R., Chandramohan, M., Berry, C., Kingsmore, D. (2015) Immediate access arteriovenous grafts versus tunnelled central venous catheters: study protocol for a randomised controlled trial. Trials, 16, (doi: 10.1186/s13063-015-0556-x)
Dalzell, J. R., Cannon, J. A., Simpson, J., Gardner, R. S., Petrie, M. C. (2015) Improving outcomes in peripartum cardiomyopathy. Expert Review of Cardiovascular Therapy, 13, pp. 665-671. (doi: 10.1586/14779072.2015.1040767)
Mangion, K., Carrick, D., Payne, A., McClure, J., Mason, M., Petrie, M., McEntegart, M., Eteiba, H., Oldroyd, K., Berry, C. (2015) Infarct burden following multivessel PCI vs. infarct-only PCI in patients with acute STEMI: the Glasgow PRAMI CMR sub-study. Journal of Cardiovascular Magnetic Resonance, 17, (doi: 10.1186/1532-429X-17-S1-O9)
Souteyrand, G., Amabile, N., Combaret, N., Hammas, S., Prati, F., Berry, C., Pereira, B., Lusson, J.-R., Caussin, C., Motreff, P. (2015) Invasive management without stents in selected acute coronary syndrome patients with a large thrombus burden: a prospective study of optical coherence tomography guided treatment decisions. EuroIntervention, 11, pp. 895-904. (doi: 10.4244/eijy14m07_18)
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Mangion, K., Carrick, D., Payne, A. R., McClure, J., Mason, M., Petrie, M., McEntegart, M., Eteiba, H., Oldroyd, K. G., Berry, C. (2015) Left ventricular outcomes following multivessel PCI vs. infarct artery-only PCI in patients with acute STEMI: the Glasgow PRAMI CMR sub-study. Journal of Cardiovascular Magnetic Resonance, 17, (doi: 10.1186/1532-429X-17-S1-P104)
MacCannell, K.A., Chilton, L., Smith, G.L., Giles, W.R. (2015) Mathematical simulations of sphingosine-1-phosphate actions on mammalian ventricular myofibroblasts and myocytes. Springer
Carrick, D., Haig, C., Rauhalammi, S., Ahmed, N., Mordi, I., McEntegart, M., Petrie, M., Eteiba, H., Hood, S., Watkins, S., Lindsay, M., Marous, A., Radjenovic, A., Ford, I., Tzemos, N., Oldroyd, K., Berry, C. (2015) Pathophysiology of myocardial remodeling in survivors of ST-elevation myocardial infarction revealed by native T1 mapping: inflammation, remote myocardium and prognostic significance. Journal of Cardiovascular Magnetic Resonance, 17, (doi: 10.1186/1532-429X-17-S1-Q52)
Paul, L., Brewster, S., Wyke, S., Gill, J. M.R., Alexander, G., Dybus, A., Rafferty, D. (2015) Physical activity profiles and sedentary behaviour in people following stroke: a cross-sectional study. Disability and Rehabilitation, (doi: 10.3109/09638288.2015.1041615)
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The Glasgow Biomarker Research Unit (GlasBRU) is a facility that conducts blood and urine tests for research purposes. This includes conducting tests that are often routinely conducted as part of clinical care, as well as more experimental blood tests. We then use that information to change our understanding of the causes and consequences of cardiometabolic disease, and the way we use blood tests in real clinical practice.
How do we conduct research?
We have large biobanks of blood samples from different populations and studies that we use, or we use existing data from studies that are available to healthcare researchers such as UK Biobank, SAIL, and NHS Safehaven data. For example,
- We conduct blood tests in ongoing clinical trials to better understand the consequences of interventions like weight loss or new pharmacological treatments for heart failure.
- We conduct blood tests in population-based studies (observational studies) to better understand who develops cardiometabolic diseases and why, or what the biological consequences of health and disease are.
- We use information from blood tests to understand who is at risk of disease, and then use that information to better understand which patients might be screened for disease, allowing early intervention or prevention in clinical practice.
Our collaborators and funders include researchers from across the world, industrial biomarker companies, industrial pharmacological companies, as well as charitable and UKRI funders.
Impact
Our world-class research has had an impact in a wide range of conditions and studies including:
- Weight Loss in The Diabetes Remission Clinical Trial (DiRECT)
- Heart Failure treatments (such as the DAPA-HF trial)
- Cardiovascular risk screening studies (in studies such as UK Biobank and Generation Scotland Family Study)