Biomarkers

We measure blood-based biomarkers in observational studies and intervention studies and then use that information to understand the causes and consequences of cardiometabolic disease. 

Staff

Publications

2024

Rankin, S., Fountain, C., Gemmell, A. J., Quinn, D., Henderson, A., McClure, J., Small, S., Venugopal, B., McKay, P., Slomka, P. J., Colville, D., Petrie, M. C., Meléndez, G. C., Lang, N. N. (2024) Arterial effects of anthracycline: structural & inflammatory assessments in non-human primates and lymphoma patients. Clinical Science, (doi: 10.1042/CS20241529)

Carberry, J. et al. (2024) Empagliflozin to prevent worsening of left ventricular volumes and systolic function after myocardial infarction (EMPRESS-MI) European Journal of Heart Failure, (doi: 10.1002/ejhf.3560)

Bonaca, M. P. et al. (2024) Cardiovascular safety in oncology clinical trials: JACC: CardioOncology Primer. JACC: CardioOncology, (doi: 10.1016/j.jaccao.2024.09.014)

Monzo, L., Bresso, E., Dickstein, K., Pitt, B., Cleland, J. G.F., Anker, S. D., Lam, C. S.P., Mehra, M. R., van Veldhuisen, D. J., Greenberg, B., Zannad, F., Girerd, N. (2024) Machine learning approach to identify phenotypes in patients with ischemic heart failure with reduced ejection fraction. European Journal of Heart Failure, (doi: 10.1002/ejhf.3547)

Setjiadi, D., Geddes, C., Delles, C. (2024) Blood pressure measurement technique in clinical practice in the NHS Greater Glasgow and Clyde. Journal of Human Hypertension, (doi: 10.1038/s41371-024-00984-5)

Nakada, S., Welsh, P., Celis-Morales, C., Pell, J. P., Ho, F. K. (2024) Predictive values of depression and anxiety disorder over the PREVENT predictors: development of prediction models for 10-year risk of cardiovascular disease. Canadian Medical Association Journal,

Greenlees, C., Hosseinzadeh, S., Delles, C., Mcginnigle, E. (2024) Hypertension evaluation and management in new young patients: are we doing our female patients a disservice? Blood Pressure, 33, (doi: 10.1080/08037051.2024.2387909)

Smith, C., Wallis, S., Katsas, G., Dincarslan, O., Dawson, J., Cameron, A. (2024) Impact of European Stroke Organisation secondary prevention guideline for ischaemic stroke / transient ischaemic attack. Journal of Stroke and Cerebrovascular Diseases, 33, (doi: 10.1016/j.jstrokecerebrovasdis.2024.108034)

De Biase, N., Del Punta, L., L'Hoyes, W., Pellicori, P., Cleland, J. G.F., Masini, G., Gargani, L., Moura-Ferreira, S., Hoedemakers, S., Di Fiore, V., Herbots, L., Stassen, J., Mengozzi, A., Armenia, S., Taddei, S., Masi, S., Verwerft, J., Pugliese, N. R. (2024) Associations of iron deficiency with cardiac function, congestion, exercise capacity and prognosis in heart failure. European Journal of Heart Failure, (doi: 10.1002/ejhf.3534)

Ang, D. T.Y., Carberry, J., Ford, T. J., Kamdar, A., Sykes, R., Sidik, N. P., Carrick, D., McCartney, P. J., Collison, D., Robertson, K., Shaukat, A., Rocchiccioli, J. P., McGeoch, R., Watkins, S., Hood, S., McEntegart, M., Lindsay, M., Eteiba, H., Oldroyd, K. G., Good, R., McConnachie, A., Berry, C. (2024) Coronary microvascular function and atherosclerotic plaque burden in ischaemia and no obstructive coronary arteries: a secondary analysis of the CorMicA trial. Heart, (doi: 10.1136/heartjnl-2024-324677)

Ho, F. K., Dale, C., Mizani, M. A., Bolton, T., Pearson, E. R., Valabhji, J., Delles, C., Welsh, P., Nakada, S., Mackay, D., Pell, J. P., Tomlinson, C., Petersen, S., Bray, B., Ashworth, M., Rahimi, K., Mamas, M., Halcox, J., Sudlow, C., Sofat, R., Sattar, N., CVD-COVID-UK/COVID-IMPACT Consortium, (2024) Routine measurement of cardiometabolic disease risk factors in primary care in England before, during and after the COVID-19 pandemic: a population-based cohort study. PLoS Medicine, 21, (doi: 10.1371/journal.pmed.1004485)

Badve, S. V., Bilal, A., Lee, M. M. Y., Sattar, N., Gerstein, H. C., Ruff, C. T., McMurray, J. J. V., Rossing, P., Bakris, G., Mahaffey, K. W., Mann, J. F. E., Colhoun, H. M., Tuttle, K. R., Pratley, R. E., Perkovic, V. (2024) Effects of GLP-1 receptor agonists on kidney and cardiovascular disease outcomes: a meta-analysis of randomised controlled trials. Lancet Diabetes and Endocrinology, (doi: 10.1016/S2213-8587(24)00271-7)

McGinley, K. A., Lucas-Herald, A., Connelly, P., Delles, C. (2024) Gender-affirming hormone therapy: effects on cardiovascular risk and vascular function. Endocrine Connections, (doi: 10.1530/EC-24-0222)

An, D.‐W., Martens, D. S., Mokwatsi, G. G., Yu, Y.‐L., Chori, B. S., Latosinska, A., Isiguzo, G., Eder, S., Zhang, D.‐Y., Mayer, G., Kruger, R., Brguljan‐Hitij, J., Delles, C., Mels, C. M.C., Stolarz‐Skrzypek, K., Rajzer, M., Verhamme, P., Schutte, A. E., Nawrot, T. S., Li, Y., Mischak, H., Odili, A. N., Staessen, J. A. (2024) Urinary proteomics and systems biology link eight proteins to the higher risk of hypertension and related complications in blacks versus whites. Proteomics, (doi: 10.1002/pmic.202400207)

Delles, C., Schmieder, R. E., Daly, R., Kannenkeril, D., Bosch, A., Lauder, L., Kunz, M., Böhm, M., Hamilton, G., Schmieder, R. S., Schmid, A., Herzyk, P., Mahfoud, F. (2024) Response of blood pressure to renal denervation is not associated with genetic variants. Hypertension, (doi: 10.1161/HYPERTENSIONAHA.124.23393)

Gupta, S. D., Butt, J. H., McMurray, E. G.M., Talebi, A., Matsumoto, S., Rizkala, A. R., Henderson, A. D., Desai, A. S., Lefkowitz, M., Packer, M., Rouleau, J. L., Solomon, S. D., Swedberg, K., Zile, M. R., Jhund, P. S., McMurray, J. J.V. (2024) Effects of sacubitril/valsartan according to background beta-blocker therapy in patients with heart failure and reduced ejection fraction: Insights from PARADIGM-HF. European Journal of Heart Failure, (doi: 10.1002/ejhf.3515)

Seckin, M., Petrie, M. C., Stewart, S., Johnston, B. M. (2024) A descriptive qualitative study of breathlessness and its management of Turkish individuals with self-reported heart failure. BMJ Open, 14, (doi: 10.1136/ bmjopen-2024-088335)

Ho, F. K., Mark, P. B., Lees, J. S., Pell, J. P., Strawbridge, R. J., Kimenai, D. M., Mills, N. L., Woodward, M., McMurray, J. J.V., Sattar, N., Welsh, P. (2024) A proteomics-based approach for prediction of different cardiovascular diseases and dementia. Circulation, (doi: 10.1161/CIRCULATIONAHA.124.070454)

Osmanska, J., Petrie, M. C., Docherty, K. F., Lee, M. M.Y., McMurray, J. J.V., Campbell, R. (2024) Subcutaneous furosemide in heart failure: a systematic review. European Heart Journal: Cardiovascular Pharmacotherapy, (doi: 10.1093/ehjcvp/pvae083)

Leong, D. P., Waliany, S., Abdel-Qadir, H., Atkins, K. M., Neilan, T. G., Lang, N. N., Liu, J. E., Blaes, A. H., Mian, H. S., Moore, H. N., Hajjar, L. A., Morgans, A. K., Ellis, P. M., Dent, S. (2024) Cardiovascular considerations during cancer therapy: Gaps in evidence and JACC: CardioOncology expert panel recommendations. JACC: CardioOncology, (doi: 10.1016/j.jaccao.2024.06.005)

Averbuch, T., Lee, S. F., Zagorski, B., Pandey, A., Petrie, M. C., Biering‐Sorensen, T., Xie, F., Van Spall, H. G.C. (2024) Long‐term clinical outcomes and healthcare resource utilization in male and female patients following hospitalization for heart failure. European Journal of Heart Failure, (doi: 10.1002/ejhf.3499)

Fletcher, R. A. et al. (2024) Contemporary epidemiology of hospitalised heart failure with reduced versus preserved ejection fraction in England: a retrospective, cohort study of whole-population electronic health records. Lancet Public Health, 9, pp. e871-e885. (doi: 10.1016/S2468-2667(24)00215-9)

Butt, J. H., Shen, L., Inzucchi, S. E., Docherty, K. F., Jhund, P. S., Martinez, F. A., Sabatine, M. S., Vaduganathan, M., Solomon, S. D., McMurray, J. J.V. (2024) Dapagliflozin in heart failure, type 2 diabetes, and neuropathy. JACC: Heart Failure, 12, pp. 1946-1948. (doi: 10.1016/j.jchf.2024.07.017)

Fullerton, J. L., Hay, J., Bryant-Craig, C., Atkinson, J., Smith, D. H., Stewart, W. (2024) Pediatric traumatic brain injury and microvascular blood-brain barrier pathology. JAMA Network Open, 7, (doi: 10.1001/jamanetworkopen.2024.46767)

Main, A., Mary, S., Sin, Y. Y., Wright, T. A., Ling, J., Blair, C. M., Smith, G. L., Fuller, W., Baillie, G. S. (2024) SUMOylation of cardiac myosin binding protein-C reduces its phosphorylation and results in impaired relaxation following treatment with isoprenaline. International Journal of Biochemistry and Cell Biology, 176, (doi: 10.1016/j.biocel.2024.106668)

Pontiroli, A. E., Tagliabue, E., Madotto, F., Leoni, O., Antonelli, B., Carluccio, E., Bandera, F., Galati, G., Pellicori, P., Lund, L. H., Ambrosio, G. (2024) Association of non-cardiac comorbidities and sex with long-term re-hospitalization for heart failure. European Journal of Internal Medicine, (doi: 10.1016/j.ejim.2024.10.018)

Rochmawati, I. D., Deo, S., Lees, J. S., Mark, P. B., Sattar, N., Celis-Morales, C., Pell, J. P., Welsh, P., Ho, F. K. (2024) Adding traditional and emerging biomarkers for risk assessment in secondary prevention: a prospective cohort study of 20,656 patients with cardiovascular disease. European Journal of Preventive Cardiology, (doi: 10.1093/eurjpc/zwae352)

Xiong, X., Lui, D. T.W., Ju, C., Zhou, Z., Xu, C., Welsh, P., Sattar, N., Celis-Morales, C., Pell, J. P., Wong, I. C.K., Wong, C. K.H., Ho, F. (2024) Associations of serum lipid traits with fracture and osteoporosis: a prospective cohort study from the UK Biobank. Journal of Cachexia, Sarcopenia and Muscle, (doi: 10.1002/jcsm.13611)

Stamatakis, E., Ahmadi, M., Biswas, R. K., Del Pozo Cruz, B., Thøgersen-Ntoumani, C., Murphy, M. H., Sabag, A., Lear, S., Chow, C., Gill, J. M.R., Hamer, M. (2024) Device-measured vigorous intermittent lifestyle physical activity (VILPA) and major adverse cardiovascular events: evidence of sex differences. British Journal of Sports Medicine, (doi: 10.1136/bjsports-2024-108484)

Dieden, A., Girerd, N., Ottosson, F., Molvin, J., Pareek, M., Melander, O., Bachus, E., Råstam, L., Lindblad, U., Daka, B., Leósdóttir, M., Nilsson, P. M., Olsen, M. H., Clark, A. L., Cleland, J. G.F., Delles, C., González, A., Lamiral, Z., Duarte, K., Rossignol, P., Zannad, F., Gudmundsson, P., Jujić, A., Magnusson, M. (2024) Proteomic biomarkers and pathway analysis for progression to heart failure in three epidemiological representative cohorts. European Journal of Heart Failure, (doi: 10.1002/ejhf.3502)

Foley, P.W., Kalra, P.R., Cleland, J.G.F., Petrie, M.C., Kalra, P.A., Squire, I., Campbell, P., Chapman, C., Donnelly, P., Graham, F., Hannah, A., Lang, N.N., Matthews, I., Leslie, S.J., Pellicori, P., Piper, S., Ray, R., Savage, H.O., Spencer, C., Walsh, J., Wong, Y., Ford, I. (2024) Effect of correcting iron deficiency on the risk of serious infection in heart failure insights from the IRONMAN trial. European Journal of Heart Failure, (doi: 10.1002/ejhf.3504)

Lu, H., Claggett, B. L., Packer, M., Pfeffer, M. A., Swedberg, K., Rouleau, J., Zile, M. R., Lefkowitz, M., Desai, A. S., Jhund, P. S., McMurray, J. J.V., Solomon, S. D., Vaduganathan, M. (2024) Visit‐to‐visit changes in heart rate in heart failure: A pooled participant‐level analysis of the PARADIGM‐HF and PARAGON‐HF trials. European Journal of Heart Failure, (doi: 10.1002/ejhf.3487)

Riddell, A., Flynn, A., Bergugnat, H., Dowsett, L. B., Miller, A. A. (2024) SDMA as a marker and mediator in cerebrovascular disease. Clinical Science, 138, pp. 1305-1323. (doi: 10.1042/CS20241021)

Alharbi, A., Nurfianti, A., Mullen, R. F., McClure, J. D., Miller, W. H. (2024) The effectiveness of simulation-based learning (SBL) on students' knowledge and skills in nursing programs: a systematic review. BMC Medical Education, 24, (doi: 10.1186/s12909-024-06080-z)

Varga, C. R., Cleland, J. G.F., Abraham, W. T., Lip, G. Y.H., Leyva, F., Hatamizadeh, P. (2024) Implantable cardioverter defibrillator and resynchronization therapy in patients with overt chronic kidney disease. Journal of the American College of Cardiology, 84, pp. 1342-1362. (doi: 10.1016/j.jacc.2024.05.081)

Ho, F., Allan, M., Shao, H., Man, K. K.C., Jani, B. D., Lyall, D., Hastie, C., Fleming, M., Mackay, D., Cleland, J. G.F., Delles, C., Dundas, R., Lewsey, J., Ip, P., Wong, I., Welsh, P., Pearce, A., Wright, C. M., Minnis, H., Katikireddi, V., Pell, J. P. (2024) Maternal and pregnancy factors contributing to the association between area deprivation and infant mortality in England: a retrospective cohort study. Lancet Regional Health - Europe, (doi: 10.1016/j.lanepe.2024.101075)

Lee, M., Petrie, M. C., Cleland, J. G.F., Donnelly, P., Francis, M., Hannah, A., Japp, A. G., Labinjoh, C., Lang, N. N., Mainsty, C., Petrie, C. J., Piper, S. E., Williams, S. G., Ford, I., Kalra, P. R., IRONMAN Trial Investigators, (2024) Administration of ferric derisomaltose for iron deficiency and heart failure during hospital admission or at the clinic – insights from the IRONMAN trial. European Journal of Heart Failure, 26, pp. 2293-2295. (doi: 10.1002/ejhf.3394)

Liu, Q., Celis-Morales, C., Lees, J. S., Sattar, N., Ho, F., Pell, J. P., Mark, P. B., Welsh, P. (2024) Change in physical activity and its association with decline in kidney function: A UK Biobank-based cohort study. Journal of Cachexia, Sarcopenia and Muscle, 15, pp. 2046-2055. (doi: 10.1002/jcsm.13551)

Cleland, J. G.F. (2024) Home-time is good, but feeling well is better: patient-journey and quality-home-time as endpoints in heart failure trials and registries. Circulation: Heart Failure, 17, (doi: 10.1161/CIRCHEARTFAILURE.124.012263)

Abdin, A., Jhund, P. S. (2024) Implementation of guideline‐directed medical therapy for heart failure: Progress achieved, work ahead! European Journal of Heart Failure, 26, pp. 2258-2260. (doi: 10.1002/ejhf.3438)

Sliwa, K., Rakisheva, A., Viljoen, C., Pfeffer, T., Simpson, M., Jackson, A. M., Petrie, M. C., van der Meer, P., Al Farhan, H., Jovanova, S., Mbakwem, A., Sinagra, G., Van Craenenbroeck, E., Hoevelmann, J., Johnson, M. R., Mindham, R., Chioncel, O., Kahl, K. G., Rosano, G., Tschöpe, C., Mebazaa, A., Seferovic, P., Bauersachs, J. (2024) Living with peripartum cardiomyopathy: A statement from the Heart Failure Association and the Association of Cardiovascular Nursing and Allied Professions of the European Society of Cardiology. European Journal of Heart Failure, 26, pp. 2143-2154. (doi: 10.1002/ejhf.3377)

Pellicori, P., Cuthbert, J. J., Clark, A. L., Cleland, J. G.F. (2024) Managing water and salt balance in heart failure: Is there anything else to consider other than diet and diuretics? European Journal of Heart Failure, 26, pp. 2140-2142. (doi: 10.1002/ejhf.3374)

Keene, D. et al. (2024) Predictors of the efficacy of His bundle pacing in patients with a prolonged PR interval: A stratified analysis of the HOPE‐HF randomized controlled trial. European Journal of Heart Failure, 26, pp. 2261-2268. (doi: 10.1002/ejhf.3367)

Lee, M., Aimo, A., Bayés-Genís, A. (2024) Reverse cardiac remodelling: VICTORIA for inflammation and cardiac metabolism. European Journal of Heart Failure, 26, pp. 2240-2242. (doi: 10.1002/ejhf.3421)

Yu, Y.-L. et al. (2024) Urinary proteomic signature of mineralocorticoid receptor antagonism by spironolactone: evidence from the HOMAGE trial. Heart, 110, pp. 1180-1187. (doi: 10.1136/heartjnl-2023-323796)

Lee, M. M.Y., Codina, P., Tomasoni, D., Aimo, A. (2024) What’s new in heart failure? October 2024. European Journal of Heart Failure, 26, pp. 2049-2054. (doi: 10.1002/ejhf.3492)

Beazer, J. D., Sillars, A., Beck, S., Christoffersen, C., Ferraz, M. J., Mulder, M., Graham, D., Karlsson, H., Ljunggren, S. A., Gill, J. M. R., Freeman, D. J. (2024) Favourable HDL composition in endurance athletes is not associated with changes in HDL in vitro antioxidant and endothelial anti-inflammatory function. Bioscience Reports, (doi: 10.1042/BSR20241165)

Cheng, L., Hammersley, D., Ragavan, A., Javed, S., Mukhopadhyay, S., Gregson, J., Han, J., Khalique, Z., Lota, A., Pantazis, A., Baksi, A. J., Carr‐White, G., de Marvao, A., Ware, J., Tayal, U., Pennell, D. J., Cleland, J. G.F., Prasad, S. K., Halliday, B. P. (2024) Long‐term follow‐up of the TRED ‐ HF trial: Implications for therapy in patients with dilated cardiomyopathy and heart failure remission. European Journal of Heart Failure, (doi: 10.1002/ejhf.3475)

Wang, X., Pabon, M. A., Cikes, M., Jering, K., Mullens, W., Kober, L., Jhund, P. S., Kovacs, A., Merkely, B., Zhou, Y., McMurray, J. J.V., Shah, A. M., Hegde, S. M., Claggett, B., Pfeffer, M. A., Solomon, S. D. (2024) Sex differences in cardiac structure and function following acute myocardial infarction: Insights from the PARADISE‐MI echocardiographic substudy. European Journal of Heart Failure, (doi: 10.1002/ejhf.3472)

Jhund, P. S., Talebi, A., Henderson, A. D., Claggett, B. L., Vaduganathan, M., Desai, A. S., Lam, C. S.P., Pitt, B., Senni, M., Shah, S. J., Voors, A. A., Zannad, F., Solomon, S. D., McMurray, J. J.V. (2024) Mineralocorticoid receptor antagonists in heart failure: an individual patient level meta-analysis. Lancet, 404, pp. 1119-1131. (doi: 10.1016/S0140-6736(24)01733-1)

Anderson, J. J., Deo, S. V., Welsh, P., Mackay, D. F., Ho, F. K., Ferguson, L. D., Celis-Morales, C., Gill, J.R., Pell, J. P., Sattar, N. (2024) In which common chronic conditions can (or cannot) obesity and lifestyle factors explain higher concentrations of C-reactive protein? Diabetes, Obesity and Metabolism, (doi: 10.1111/dom.15949)

Pabon, M. A., Vaduganathan, M., Claggett, B. L., Chatur, S., Siqueira, S., Marti‐Castellote, P., de Boer, R. A., Hernandez, A. F., Inzucchi, S. E., Kosiborod, M. N., Lam, C. S.P., Martinez, F., Shah, S. J., Desai, A. S., Jhund, P. S., McMurray, J. J.V., Solomon, S. D., Vardeny, O. (2024) In‐hospital course of patients with heart failure with improved ejection fraction in the DELIVER trial. European Journal of Heart Failure, (doi: 10.1002/ejhf.3410)

Valentova, M., Vatic, M., Garfias-Veitl, T., Sandek, A., Bekfani, T., Jankowska, E. A., Cleland, J. G.F., Clark, A. L., Lainscak, M., Ahmed, A., Jauert, N., Hasenfuss, G., Anker, S. D., Doehner, W., von Haehling, S. (2024) Diabetes mellitus is associated with low exercise capacity and impaired peripheral vasodilation in patients with heart failure – a propensity score-matched stud. Diabetes Research and Clinical Practice,

Greene, S. J. et al. (2024) Cardiovascular and renal treatment in heart failure patients with hyperkalemia or high risk of hyperkalemia: rationale and design of the CARE-HK in HF registry. Journal of Cardiac Failure, (doi: 10.1016/j.cardfail.2024.08.048)

Zhou, M., Mary, S., Delles, C., Padmanabhan, S., Graham, D., McBride, M. W., Dominiczak, A. (2024) Insights into uromodulin and blood pressure. Current Hypertension Reports, (doi: 10.1007/s11906-024-01317-0)

Cuthbert, J. J., Cleland, J. G. F., Pellicori, P., Clark, A. L. (2024) Natriuresis guided diuresis in patients admitted to hospital with heart failure – barking up the wrong tree? Journal of Cardiac Failure,

Coats, C. J. et al. (2024) Cardiac biomarkers and effects of aficamten in obstructive hypertrophic cardiomyopathy: the SEQUOIA-HCM trial. European Heart Journal, (doi: 10.1093/eurheartj/ehae590)

Lu, H., Claggett, B. L., Packer, M., Pfeffer, M. A., Lam, C. S.P., Zile, M. R., Desai, A. S., Jhund, P., Lefkowitz, M., McMurray, J. J.V., Solomon, S. D., Vaduganathan, M. (2024) Sacubitril/valsartan reduces incident anaemia and iron therapy utilization in heart failure: The PARAGON‐HF trial. European Journal of Heart Failure, (doi: 10.1002/ejhf.3414)

Morrow, A. et al. (2024) Zibotentan in microvascular angina: a randomized, placebo-controlled, crossover trial. Circulation, (doi: 10.1161/CIRCULATIONAHA.124.069901)

Al-Abdullah, L., Ahern, A., Welsh, P., Logue, J. (2024) A predictive model for medium-term weight loss response in people with type 2 diabetes engaging in behavioural weight management interventions. Diabetes, Obesity and Metabolism, 26, pp. 3653-3662. (doi: 10.1111/dom.15706)

van der Meer, P., van Essen, B., Viljoen, C., Böhm, M., Jackson, A., Hilfiker-Kleiner, D., Hoevelmann, J., Mebazaa, A., Farhan, H. A., Goland, S., Ouwerkerk, W., Petrie, M. C., Seferović, P. M., Tromp, J., Sliwa, K., Bauersachs, J. (2024) Bromocriptine treatment and outcomes in peripartum cardiomyopathy: the EORP PPCM registry. European Heart Journal, (doi: 10.1093/eurheartj/ehae559)

Butt, J., Jhund, P. S., Docherty, K. F., Claggett, B. L., Vaduganathan, M., Bachus, E., Hernandez, A. F., Lam, C. S.P., Inzucchi, S. E., Martinez, F. A., de Boer, R. A., Kosiborod, M. N., Desai, A. S., Køber, L., Ponikowski, P., Sabatine, M. S., Solomon, S. D., McMurray, J. J.V. (2024) Dapagliflozin and timing of prior heart failure hospitalization a patient-level meta-analysis of DAPA-HF and DELIVER. JACC: Heart Failure, 12, pp. 1586-1599. (doi: 10.1016/j.jchf.2024.01.018)

Seferović, P. M., Paulus, W. J., Rosano, G., Polovina, M., Petrie, M. C., Jhund, P. S., Tschöpe, C., Sattar, N., Piepoli, M., Papp, Z., Standl, E., Mamas, M. A., Valensi, P., Linhart, A., Lalić, N., Ceriello, A., Döhner, W., Ristić, A., Milinković, I., Seferović, J., Cosentino, F., Metra, M., Coats, A. J.S. (2024) Diabetic myocardial disorder. A clinical consensus statement of the Heart Failure Association of the ESC and the ESC Working Group on Myocardial & Pericardial Diseases. European Journal of Heart Failure, 26, pp. 1893-1903. (doi: 10.1002/ejhf.3347)

Ryan, M., Taylor, D., Dodd, M., Spertus, J. A., Kosiborod, M. N., Shaukat, A., Docherty, K. F., Clayton, T., Perera, D., Petrie, M. C., REVIVED-BCIS2 Investigators, (2024) Effect of PCI on health status in ischemic left ventricular dysfunction: insights from REVIVED-BCIS2. JACC: Heart Failure, 12, pp. 1553-1562. (doi: 10.1016/j.jchf.2024.03.010)

Abdin, A., Kondo, T., Böhm, M., Jhund, P. S., Claggett, B. L., Vaduganathan, M., Hernandez, A. F., Lam, C. S.P., Inzucchi, S. E., Martinez, F. A., de Boer, R. A., Desai, A. S., Køber, L., Sabatine, M. S., Petersson, M., Bachus, E., Solomon, S. D., McMurray, J. (2024) Effects of dapagliflozin according to QRS duration across the spectrum of left ventricular ejection fraction: an analysis of DAPA-HF and DELIVER. European Journal of Heart Failure, 26, pp. 1952-1963. (doi: 10.1002/ejhf.3350)

Reza, N., Pellicori, P., Starling, R. C. (2024) REVOLUTION in heart failure care and SELECT highlights from the European Society of Cardiology-Heart Failure Association Heart Failure and World Congress on Acute Heart Failure 2024. Journal of Cardiac Failure, 30, pp. 1157-1160. (doi: 10.1016/j.cardfail.2024.05.004)

Butt, J. H., McMurray, J. J.V., Claggett, B. L., Jhund, P. S., Neuen, B. L., McCausland, F., Desai, A., Lam, C. S.P., Pitt, B., Pfeffer, M. A., Packer, M., Beldhuis, I., Voors, A. A., Zannad, F., Heerspink, H. J.L., Solomon, S. D., Vaduganathan, M. (2024) Therapeutic effects of heart failure medical therapies on standardized kidney outcomes: Comprehensive individual participant-level analysis of 6 randomized clinical trials. Circulation, (doi: 10.1161/circulationaha.124.071110)

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Pellicori, P., Hunter, D., Khin, H. H. E., Cleland, J. G.F. (2024) How to diagnose and treat venous congestion in heart failure. European Heart Journal, (doi: 10.1093/eurheartj/ehad883)

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2023

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Glen, C., Adam, S., Coats, C. J., Lang, N. N. (2023) Reply: Cardiotoxicity of BRAF/MEK inhibitors according to HFA/ICOS cardiotoxicity risk category. JACC: CardioOncology, 5, pp. 850. (doi: 10.1016/j.jaccao.2023.10.003)

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Zahir Anjum, D., Strange, J. E., Fosbøl, E., Garred, C. H., Malik, M. E., Andersson, C., Jhund, P. S., McMurray, J. J.V., Petrie, M. C., Kober, L., Schou, M. (2023) Initiation of medical therapy for heart failure patients according to kidney function: a Danish nationwide study. Clinical Epidemiology, 15, pp. 855-866. (doi: 10.2147/clep.s412787)

Flett, A., Cebula, A., Nicholas, Z., Adam, R., Ewings, S., Prasad, S., Cleland, J. G.F., Eminton, Z., Curzen, N. (2023) Rationale and study protocol for the BRITISH randomised trial (using cardiovascular magnetic resonance identified scar as the Benchmark Risk Indication Tool for Implantable cardioverter defibrillators in patients with non-ischaemic cardiomyopathy and severe systolic heart failure) American Heart Journal, 266, pp. 149-158. (doi: 10.1016/j.ahj.2023.09.008)

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2022

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Collet, C., Collison, D., Mizukami, T., McCartney, P., Sonck, J., Ford, T., Munhoz, D., Berry, C., De Bruyne, B., Oldroyd, K. (2022) Differential improvement in angina and health-related quality of life after PCI in focal and diffuse coronary artery disease. JACC: Cardiovascular Interventions, 15, pp. 2506-2518. (doi: 10.1016/j.jcin.2022.09.048)

Kalra, P. R., Cleland, J. G.F., Petrie, M. C., Thomson, E. A., Kalra, P. A., Squire, I. B., Ahmed, F. Z., Al-Mohammad, A., Cowburn, P. J., Foley, P. W.X., Graham, F. J., Japp, A. G., Lane, R. E., Lang, N. N., Ludman, A. J., Macdougall, I. C., Pellicori, P., Ray, R., Robertson, M., Seed, A., Ford, I. (2022) Intravenous ferric derisomaltose in patients with heart failure and iron deficiency in the UK (IRONMAN): an investigator-initiated, prospective, randomised, open-label, blinded-endpoint trial. Lancet, 400, pp. 2199-2209. (doi: 10.1016/S0140-6736(22)02083-9)

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Alnuwaysir, R. I.S., Grote Beverborg, N., Hoes, M. F., Markousis‐Mavrogenis, G., Gomez, K. A., van der Wal, H. H., Cleland, J. G.F., Dickstein, K., Lang, C. C., Ng, L. L., Ponikowski, P., Anker, S. D., van Veldhuisen, D. J., Voors, A. A., van der Meer, P. (2022) Additional burden of iron deficiency in heart failure patients beyond the cardio‐renal anaemia syndrome: findings from the BIOSTAT‐CHF study. European Journal of Heart Failure, 24, pp. 192-204. (doi: 10.1002/ejhf.2393)

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2021

Andersen, E., van der Ploeg, H. P., van Mechelen, W., Gray, C. M., Mutrie, N., van Nassau, F., Jelsma, J. G. M., Anderson, A. S., Silva, M. N., Pereira, H. V., McConnachie, A., Sattar, N., Sørensen, M., Røynesdal, Ø. B., Hunt, K., Roberts, G. C., Wyke, S., Gill, J. M.R. (2021) Contributions of changes in physical activity, sedentary time, diet and body weight to changes in cardiometabolic risk. International Journal of Behavioral Nutrition and Physical Activity, 18, (doi: 10.1186/s12966-021-01237-1)

Mooney, L., Hawkins, N. M., Jhund, P. S., Redfield, M. M., Muthiah Vaduganathan, M., Desai, A. S., Rouleau, J. L., Minamisawa, M., Shah, A. M., Lefkowitz, M. P., Zile, M. R., Van Veldhuisen, D. J., Pfeffer, M. A., Anand, I. S., Maggioni, A. P., Senni, M., Claggett, B. L., Solomon, S. D., McMurray, J. J. V. (2021) Impact of chronic obstructive pulmonary disease in patients with heart failure with preserved ejection fraction: insights from PARAGON‐HF. Journal of the American Heart Association, 10, (doi: 10.1161/JAHA.121.021494)

Petermann-Rocha, F., Lyall, D. M., Gray, S. R., Gill, J. M.R., Sattar, N., Welsh, P., Quinn, T. J., Stewart, W., Pell, J. P., Ho, F. K., Celis-Morales, C. (2021) Dose-response association between device-measured physical activity and incident dementia: a prospective study from UK Biobank. BMC Medicine, 19, (doi: 10.1186/s12916-021-02172-5)

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Butt, J. H., Adamson, C., Docherty, K. F., de Boer, R. A., Petrie, M. C., Inzucchi, S. E., Kosiborod, M. N., Maria Langkilde, A., Lindholm, D., Martinez, F. A., Bengtsson, O., Schou, M., O’Meara, E., Ponikowski, P., Sabatine, M. S., Sjöstrand, M., Solomon, S. D., Jhund, P. S., McMurray, J. J.V., Køber, L. (2021) Efficacy and safety of dapagliflozin in heart failure with reduced ejection fraction according to N-terminal pro-B-type natriuretic peptide: insights from the DAPA-HF trial. Circulation: Heart Failure, 14, (doi: 10.1161/CIRCHEARTFAILURE.121.008837)

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Desai, A. S., Vaduganathan, M., Cleland, J. G., Claggett, B. L., Barkoudah, E., Finn, P., McCausland, F. R., Yilmaz, M. B., Lefkowitz, M., Shi, V., Pfeffer, M. A., McMurray, J. J.V., Soloman, S. D. (2021) Mode of death in patients with heart failure and preserved ejection fraction: insights from PARAGON-HF. Circulation: Heart Failure, 14, (doi: 10.1161/CIRCHEARTFAILURE.121.008597)

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Butt, J. H., Nicolau, J. C., Verma, S., Docherty, K. F., Petrie, M. C., Inzucchi, S. E., Schou, M., Kosiborod, M. N., Langkilde, A. M., Martinez, F. A., Ponikowski, P., Sabatine, M. S., Sjöstrand, M., Solomon, S. D., Bengtsson, O., Jhund, P. S., McMurray, J., Køber, L. (2021) Efficacy and safety of dapagliflozin according to aetiology in heart failure with reduced ejection fraction: insights from the DAPA-HF trial. European Journal of Heart Failure, 23, pp. 601-613. (doi: 10.1002/ejhf.2124)

Mbakwem, A. C., Bauersachs, J., Viljoen, C., Hoevelmann, J., Meer, P., Petrie, M. C., Mebazaa, A., Goland, S., Karaye, K., Laroche, C., Sliwa, K. (2021) Electrocardiographic features and their echocardiographic correlates in peripartum cardiomyopathy: results from the ESC EORP PPCM registry. ESC Heart Failure, 8, pp. 879-889. (doi: 10.1002/ehf2.13172)

van Dorst, D. C.H., Dobbin, S. J.H., Neves, K. B., Herrmann, J., Herrmann, S. M., Versmissen, J., Mathijssen, R. H.J., Danser, A.H. J., Lang, N. N. (2021) Hypertension and prohypertensive antineoplastic therapies in cancer patients. Circulation Research, 128, pp. 1040-1061. (doi: 10.1161/CIRCRESAHA.121.318051)

Ferreira, J. P., Lam, C. S. P., Anker, S. D., Mehra, M. R., van Veldhuisen, D. J., Byra, W. M., La Police, D. A., Cleland, J. G.F., Greenberg, B., Zannad, F. (2021) Plasma D‐dimer concentrations predicting stroke risk and rivaroxaban benefit in patients with heart failure and sinus rhythm: an analysis from the COMMANDER‐HF trial. European Journal of Heart Failure, 23, pp. 648-656. (doi: 10.1002/ejhf.2003)

Ferreira, J. P. et al. (2021) Proteomic and mechanistic analysis of spironolactone in patients at risk for HF. JACC: Heart Failure, 9, pp. 268-277. (doi: 10.1016/j.jchf.2020.11.010)

Ferguson, L. D., Linge, J., Leinhard, O. D., Woodward, R., Hall Barrientos, P., Roditi, G., Radjenovic, A., McInnes, I. B., Siebert, S., Sattar, N. (2021) Psoriatic arthritis is associated with adverse body composition predictive of greater coronary heart disease and type 2 diabetes propensity – a cross-sectional study. Rheumatology, 60, pp. 1858-1862. (doi: 10.1093/rheumatology/keaa604)

Sliwa, K. et al. (2021) Risk stratification and management of women with cardiomyopathy/heart failure planning pregnancy or presenting during/after pregnancy: a position statement from the Heart Failure Association of the European Society of Cardiology Study Group on Peripartum Cardiomyopathy. European Journal of Heart Failure, 23, pp. 527-540. (doi: 10.1002/ejhf.2133)

Petermann-Rocha, F., Parra-Soto, S., Gray, S., Anderson, J., Welsh, P., Gill, J., Sattar, N., Ho, F. K., Celis-Morales, C., Pell, J. P. (2021) Vegetarians, fish, poultry and meat-eaters: who has higher risk of CVD incidence and mortality? A prospective study from UK Biobank. European Heart Journal, 42, pp. 1136-1143. (doi: 10.1093/eurheartj/ehaa939)

Sigfrid, L. et al. (2021) What is the recovery rate and risk of long-term consequences following a diagnosis of COVID-19? A harmonised, global longitudinal observational study protocol. BMJ Open, 11, (doi: 10.1136/bmjopen-2020-043887)

Uijl, A., Vaartjes, I., Denaxas, S., Hemingway, H., Shah, A. D., Cleland, J., Grobbee, D. E., Hoes, A. W., Asselbergs, F. W., Koudstaal, S. (2021) Temporal trends in heart failure medication prescription in a population-based cohort study. BMJ Open, 11, (doi: 10.1136/bmjopen-2020-043290)

Mortensen, P., Gao, H., Smith, G., Simitev, R. D. (2021) Action potential propagation and block in a model of atrial tissue with myocyte-fibroblast coupling. Mathematical Medicine and Biology, 38, pp. 106-131. (doi: 10.1093/imammb/dqaa014)

Pellicori, P., Doolub, G., Wong, C. M., Lee, K. S., Mangion, K., Ahmad, M., Berry, C., Squire, I., Lambiase, P., Lyon, A. R., McConnachie, A., Taylor, R. S., Cleland, J. G.F. (2021) COVID-19 and its cardiovascular effects: a systematic review of prevalence studies. Cochrane Database of Systematic Reviews, 2021, (doi: 10.1002/14651858.CD013879)

Briscoe, M., Sykes, R., Krystofiak, T., Peck, O., Mangion, K., Berry, C. (2021) Clinical significance of coronavirus disease 2019 in hospitalized patients with myocardial injury. Clinical Cardiology, 44, pp. 332-339. (doi: 10.1002/clc.23530)

Smart, N. A., Pearson, M. J., Taylor, R. S., Cleland, J. (2021) Exercise training for heart failure with preserved ejection fraction (ExTraMATCH III): protocol for an individual patient data meta-analysis. Journal of Clinical Exercise Physiology, 10, pp. 3-11. (doi: 10.31189/2165-7629-10.1.3)

Mordi, I. R., Ouwerkerk, W., Anker, S. D., Cleland, J. G., Dickstein, K., Metra, M., Ng, L. L., Samani, N. J., van Veldhuisen, D. J., Zannad, F., Voors, A. A., Lang, C. C. (2021) Heart failure treatment up-titration and outcome and age: an analysis of BIOSTAT-CHF. European Journal of Heart Failure, 23, pp. 436-444. (doi: 10.1002/ejhf.1799)

Ferreira, J. P., Cleland, J. G.F., Lam, C. S.P., van Veldhuisen, D., Byra, W. M., La Police, D. A., Anker, S. D., Mehra, M. R., Leroy, C., Eschwege, V., Toussaint-Hacquard, M., Rossignol, P., Greenberg, B., Zannad, F. (2021) Impact of geographic region on the COMMANDER-HF Trial. JACC: Heart Failure, 9, pp. 201-211. (doi: 10.1016/j.jchf.2020.11.007)

Crouch, S. H., Botha-Le Roux, S., Delles, C., Graham, L. A., Schutte, A. E. (2021) Inflammation and salt in young adults: the African-PREDICT study. European Journal of Nutrition, 60, pp. 873-882. (doi: 10.1007/s00394-020-02292-3)

Ferguson, L. D., Sattar, N., McInnes, I. B. (2021) Managing cardiovascular risk in patients with rheumatic disease. Medical Clinics of North America, 105, pp. 247-262. (doi: 10.1016/j.mcna.2020.09.010)

Sykes, R. A., Mohamed, M. O., Kwok, C. S., Mamas, M. A., Berry, C. (2021) Percutaneous coronary intervention and 30-day unplanned readmission with chest pain in the United States (nationwide readmissions database) Clinical Cardiology, 44, pp. 291-306. (doi: 10.1002/clc.23543)

Neves, K. B., Morris, H., Alves-Lopes, R., Muir, K. W., Moreton, F., Delles, C., Montezano, A. C., Touyz, R. M. (2021) Peripheral arteriopathy caused by Notch3 gain-of-function mutation involves ER and oxidative stress and blunting of NO∕sGC∕cGMP pathway. Clinical Science, 135, pp. 753-773. (doi: 10.1042/CS20201412)

Doherty, D. J., Sykes, R., Mangion, K., Berry, C. (2021) Predictors of microvascular reperfusion after myocardial infarction. Current Cardiology Reports, 23, (doi: 10.1007/s11886-021-01442-1)

Tomasoni, D., Petrie, M. C., Adamo, M., Metra, M. (2021) Renin-angiotensin-aldosterone inhibitors and COVID-19: nearing the end of a media-fuelled controversy. European Journal of Heart Failure, 23, pp. 486-488. (doi: 10.1002/ejhf.2098)

Cameron, A. C., Neves, K. B., White, J., Touyz, R. M., Lang, N. N. (2021) Reply: Cisplatin-associated aortic thrombosis: a review of cases reported to the FDA adverse event reporting system. JACC: CardioOncology, 3, pp. 166. (doi: 10.1016/j.jaccao.2021.01.005)

Sze, S., Pellicori, P., Zhang, J., Weston, J., Clark, A. L. (2021) The impact of malnutrition on short-term morbidity and mortality in ambulatory patients with heart failure. American Journal of Clinical Nutrition, 113, pp. 695-705. (doi: 10.1093/ajcn/nqaa311)

Hortigon-Vinagre, M.P., Zamora, V., Burton, F. L., Smith, G. L. (2021) The use of voltage sensitive dye di-4-ANEPPS and video-based contractility measurements to assess drug effects on excitation-contraction coupling in human induced pluripotent stem cell-derived cardiomyocytes. Journal of Cardiovascular Pharmacology, 77, pp. 280-290. (doi: 10.1097/FJC.0000000000000937)

Lee, M. M.Y. et al. (2021) Invasive versus medically managed acute coronary syndromes with prior bypass (CABG-ACS): insights into the registry versus randomised trial populations. Open Heart, 8, (doi: 10.1136/openhrt-2020-001453)

Ehteshami-Afshar, S., Mooney, L., Dewan, P., Desai, A. S., Lang, N. N., Lefkowitz, M. P., Petrie, M. C., Rizkala, A. R., Rouleau, J. L., Solomon, S. D., Swedberg, K., Shi, V. C., Zile, M. R., Packer, M., McMurray, J. J.V., Jhund, P. S., Hawkins, N. M. (2021) Clinical characteristics and outcomes of patients with heart failure with reduced ejection fraction and chronic obstructive pulmonary disease: insights from PARADIGM-HF. Journal of the American Heart Association, 10, (doi: 10.1161/JAHA.120.019238)

Thom, G., McIntosh, A., Messow, C.-M., Leslie, W. S., Barnes, A. C., Brosnahan, N., McCombie, L., Malkova, D., Al-Mrabeh, A., Zhyzhneuskaya, S., Welsh, P., Sattar, N., Taylor, R., Lean, M. E.J. (2021) Weight loss induced increase in fasting ghrelin concentration is a predictor of weight regain: evidence from the Diabetes Remission Clinical Trial. Diabetes, Obesity and Metabolism, 23, pp. 711-719. (doi: 10.1111/dom.14274)

Lee, M. M.Y. et al. (2021) Effect of empagliflozin on left ventricular volumes in patients with type 2 diabetes, or prediabetes, and heart failure with reduced ejection fraction (SUGAR-DM-HF) Circulation, 143, pp. 516-525. (doi: 10.1161/CIRCULATIONAHA.120.052186)

Petrie, M. C., Lee, M. M., Lang, N. N. (2021) EMPEROR-REDUCED reigns while EMPERIAL whimpers. European Heart Journal, 42, pp. 711-714. (doi: 10.1093/eurheartj/ehaa965)

Cleland, J. G.F. et al. (2021) The effect of spironolactone on cardiovascular function and markers of fibrosis in people at increased risk of developing heart failure: the heart 'OMics' in AGEing (HOMAGE) randomized clinical trial. European Heart Journal, 42, pp. 684-696. (doi: 10.1093/eurheartj/ehaa758)

Li, W., Gao, H., Mangion, K., Berry, C., Luo, X. (2021) Apparent growth tensor of left ventricular post myocardial infarction – in human first natural history study. Computers in Biology and Medicine, 129, (doi: 10.1016/j.compbiomed.2020.104168)

Inzucchi, S. E., Docherty, K. F., Køber, L., Kosiborod, M. N., Martinez, F. A., Ponikowski, P., Sabatine, M. S., Solomon, S. D., Verma, S., Bělohlávek, J., Böhm, M., Chiang, C.-E., de Boer, R. A., Diez, M., Dukát, A., Ljungman, C. E.A., Bengtsson, O., Langkilde, A. M., Sjöstrand, M., Jhund, P. S., McMurray, J. J.V. (2021) Dapagliflozin and the incidence of type 2 diabetes in patients with heart failure and reduced ejection fraction: an exploratory analysis from DAPA-HF. Diabetes Care, 44, pp. 586-594. (doi: 10.2337/dc20-1675)

Bhopal, R., Douglas, A., Sheikh, A., Wild, S.H., Gill, J.M.R., Sattar, N., Lean, M.E.J., McKnight, J., Tuomilehto, J., Wallia, S., Cezard, G. (2021) Diabetes incidence in a high-risk UK population at 7 years: linkage of the Prevention of Diabetes and Obesity in South Asians (PODOSA) trial to the Scottish Diabetes Register. Diabetic Medicine, 38, (doi: 10.1111/dme.14369)

Maznyczka, A. M., McCartney, P., Duklas, P., McEntegart, M., Oldroyd, K., Greenwood, J., Muir, D., Chowdhary, S., Gershlick, A. H., Eteiba, H., Cotton, J., Wragg, A., Curzen, N., Tait, R., Macfarlane, P., Welsh, P., Sattar, N., Petrie, M., Ford, I., Fox, K., McConnachie, A., Berry, C. (2021) Effect of coronary flow on intracoronary alteplase: a prespecified analysis from a randomised trial. Heart, 107, pp. 299-312. (doi: 10.1136/heartjnl-2020-317828)

Felker, G. M. et al. (2021) Effects of a novel nitroxyl donor in acute heart failure: the STAND-UP AHF Study. JACC: Heart Failure, 9, pp. 146-157. (doi: 10.1016/j.jchf.2020.10.012)

Donin, A. S., Nightingale, C. M., Perkin, M. R., Ussher, M., Jebb, S. A., Landberg, R., Welsh, P., Sattar, N., Adab, P., Owen, C. G., Rudnicka, A. R., Cook, D. G., Whincup, P. H. (2021) Evaluating an intervention to increase cereal fiber intake in children: a randomized controlled feasibility trial. Journal of Nutrition, 151, pp. 379-386. (doi: 10.1093/jn/nxaa347)

Halliday, B. P., Owen, R., Gregson, J., Vassiliou, V., Chen, X., Wage, R., Lota, A. S., Khalique, Z., Tayal, U., Hammersley, D. J., Jones, R. E., Baksi, A. J., Cowie, M. R., Cleland, J. G.F., Pennell, D. J., Prasad, S. K. (2021) Myocardial remodelling after withdrawing therapy for heart failure in patients with recovered dilated cardiomyopathy – insights from TRED‐HF. European Journal of Heart Failure, 23, pp. 293-301. (doi: 10.1002/ejhf.2063)

Docherty, K. F., Campbell, R. T., Brooksbank, K. J.M., Godeseth, R. L., Forsyth, P., McConnachie, A., Roditi, G., Stanley, B., Welsh, P., Jhund, P. S., Petrie, M. C., McMurray, J. J.V. (2021) Rationale and methods of a randomized trial evaluating the effect of neprilysin inhibition on left ventricular remodelling. ESC Heart Failure, 8, pp. 129-138. (doi: 10.1002/ehf2.13137)

Maznyczka, A. M., McCartney, P. J., Oldroyd, K. G., Lindsay, M., McEntegart, M., Eteiba, H., Rocchiccioli, J. P., Good, R., Shaukat, A., Robertson, K., Malkin, C. J., Greenwood, J. P., Cotton, J. M., Hood, S., Watkins, S., Collison, D., Gillespie, L., Ford, T. J., Weir, R. A.P., McConnachie, A., Berry, C. (2021) Risk stratification guided by the index of microcirculatory resistance and left ventricular end-diastolic pressure in acute myocardial infarction. Circulation: Cardiovascular Interventions, 14, (doi: 10.1161/CIRCINTERVENTIONS.120.009529)

Platz, E., Jhund, P. S. (2021) Risk stratification in patients presenting with acute heart failure. European Heart Journal: Acute Cardiovascular Care, 10, pp. 113-115. (doi: 10.1093/ehjacc/zuab005)

Al Ozairi, E., Alroudhan, D., Alsaeed, D., Voase, N., Hasan, A., Gill, J. M.R., Sattar, N., Welsh, P., Gray, C. M., Boonpor, J., Celis-Morales, C., Gray, S. R. (2021) Skeletal muscle and metabolic health – how do we increase muscle mass and function in people with type 2 diabetes. Journal of Clinical Endocrinology and Metabolism, 106, pp. 309-317. (doi: 10.1210/clinem/dgaa835)

Connelly, P. J., Clark, A., Touyz, R. M., Delles, C. (2021) Transgender adults, gender-affirming hormone therapy and blood pressure: a systematic review. Journal of Hypertension, 39, pp. 223-230. (doi: 10.1097/HJH.0000000000002632)

Gill, D., Cameron, A. C., Burgess, S., Liu, X., Doherty, D. J., Karhunen, V., Abdul-Rahim, A., Taylor-Rowan, M., Zuber, V., Tsao, P. S., Klarin, D., VA Million Veteran Program, , Evangelou, E., Elliott, P., Damrauer, S. M., Quinn, T. J., Dehghan, A., Theodoratou, E., Dawson, J., Tzoulaki, I. (2021) Urate, blood pressure, and cardiovascular disease: evidence from Mendelian randomization and meta-analysis of clinical trials. Hypertension, 77, pp. 383-392. (doi: 10.1161/HYPERTENSIONAHA.120.16547)

Jhund, P. S. et al. (2021) Efficacy of dapagliflozin on renal function and outcomes in patients with heart failure with reduced ejection fraction: results of DAPA-HF. Circulation, 143, pp. 289-309. (doi: 10.1161/CIRCULATIONAHA.120.050391)

Samuel, N. A., Cuthbert, J. J., Brown, O. I., Kazmi, S., Cleland, J. G.F., Rigby, A. S., Clark, A. L. (2021) Relation between thyroid function and mortality in patients with chronic heart failure. American Journal of Cardiology, 139, pp. 57-63. (doi: 10.1016/j.amjcard.2020.10.034)

Teerlink, J. R. et al. (2021) Cardiac myosin activation with omecamtiv mecarbil in systolic heart failure. New England Journal of Medicine, 384, pp. 105-116. (doi: 10.1056/NEJMoa2025797)

Lyall, D. M., Ward, J., Banach, M., Smith, G. D., Gill, J. G., Pell, J. P., Holmes, M. V., Sattar, N. (2021) PCSK9 genetic variants and cognitive abilities: a large-scale Mendelian randomization study. Archives of Medical Science, 17, pp. 241-244. (doi: 10.5114/aoms/127226)

Corcoran, D., Radjenovic, A., Mordi, I., Nazir, S. A., Wilson, S. J., Hinder, M., Yates, D. P., Machineni, S., Alcantara, J., Prescott, M. F., Gugliotta, B., Pang, Y., Tzemos, N., Semple, S. I., Newby, D. E., McCann, G. P., Squire, I., Berry, C. (2021) Vascular effects of serelaxin in patients with stable coronary artery disease: a randomized placebo-controlled trial. Cardiovascular Research, 117, pp. 320-329. (doi: 10.1093/cvr/cvz345)

Bekfani, T., Fudim, M., Cleland, J. G.F., Jorbenadze, A., Haehling, S., Lorber, A., Rothman, A. M.‐K., Stein, K., Abraham, W. T., Sievert, H., Anker, S. D. (2021) A current and future outlook on upcoming technologies in the remote monitoring of patients with heart failure. European Journal of Heart Failure, 23, pp. 175-185. (doi: 10.1002/ejhf.2033)

Moreton, F. C., Cullen, B., Dickie, D. A., Lopez Gonzalez, R., Santosh, C., Delles, C., Muir, K. W. (2021) Brain imaging factors associated with progression of subcortical hyperintensities in CADASIL over two year follow up. European Journal of Neurology, 28, pp. 220-228. (doi: 10.1111/ene.14534)

Dobbin, S. J.H., Petrie, M. C., Myles, R. C., Touyz, R. M., Lang, N. N. (2021) Cardiotoxic effects of angiogenesis inhibitors. Clinical Science, 135, pp. 71-100. (doi: 10.1042/CS20200305)

Davison, B. A., Senger, S., Sama, I. E., Koch, G. G., Mebazaa, A., Dickstein, K., Samani, N. J., Metra, M., Anker, S. D., Cleland, J. G., Ng, L. L., Mordi, I. R., Zannad, F., Filippatos, G. S., Hillege, H. L., Ponikowski, P., Veldhuisen, D. J., Lang, C. C., Meer, P., Núñez, J., Bayés‐Genís, A., Edwards, C., Voors, A. A., Cotter, G. (2021) Is acute heart failure a distinctive disorder? An analysis from BIOSTAT‐CHF. European Journal of Heart Failure, 23, pp. 43-57. (doi: 10.1002/ejhf.2077)

He, T., Melgarejo, J. D., Clark, A. L., Yu, Y.‐L., Thijs, L., Díez, J., López, B., González, A., Cleland, J. G., Schanstra, J. P., Vlahou, A., Latosinska, A., Mischak, H., Staessen, J. A., Zhang, Z.‐Y., Jankowski, V. (2021) Serum and urinary biomarkers of collagen type‐I turnover predict prognosis in patients with heart failure. Clinical and Translational Medicine, 11, (doi: 10.1002/ctm2.267)

Willder, J. M., McCall, P., Messow, C.-M., Gillies, M., Berry, C., Shelley, B. (2021) Study protocol for COVID-RV: a multicentre prospective observational cohort study of right ventricular dysfunction in ventilated patients with COVID-19. BMJ Open, 11, (doi: 10.1136/bmjopen-2020-042098)

Mortensen, P., Gao, H., Smith, G., Simitev, R. D. (2021) Addendum: Action potential propagation and block in a model of atrial tissue with myocyte-fibroblast coupling. Mathematical Medicine and Biology, 38, pp. 292-298. (doi: 10.1093/imammb/dqab005)

Jacobs, M., Benovoy, M., Chang, L.-C., Corcoran, D., Berry, C., Arai, A. E., Hsu, L.-Y. (2021) Automated segmental analysis of fully quantitative myocardial blood flow maps by first-pass perfusion cardiovascular magnetic resonance. IEEE Access, 9, pp. 52796-52811. (doi: 10.1109/ACCESS.2021.3070320)

Kamdar, A., Sykes, R., Morrow, A., Mangion, K., Berry, C. (2021) Cardiovascular outcomes of glucose lowering therapy in chronic kidney disease patients: a systematic review with meta-analysis. Reviews in Cardiovascular Medicine, 22, pp. 1479-1490. (doi: 10.31083/j.rcm2204152)

Da Silva Costa, A., Mortensen, P., Hortigon-Vinagre, M. P., van der Heyden, M. A. G., Burton, F. L., Gao, H., Simitev, R. D., Smith, G. L. (2021) Electrophysiology of hiPSC-cardiomyocytes co-cultured with HEK cells expressing the inward rectifier channel. International Journal of Molecular Sciences, 22, (doi: 10.3390/ijms22126621)

Anderson, J. J., Welsh, P., Ho, F. K., Ferguson, L. D., Welsh, C. E., Pellicori, P., Cleland, J. G.F., Forbes, J., Iliodromiti, S., Boyle, J., Lindsay, R., Celis-Morales, C., Gray, S. R., Katikireddi, S. V., Gill, J. M. R., Pell, J. P., Sattar, N. (2021) Ethnic differences in prevalence of actionable HbA1c levels in UK Biobank: implications for screening. BMJ Open Diabetes Research and Care, 9, (doi: 10.1136/bmjdrc-2021-002176)

Small, H. Y., Delles, C. (2021) Letter to the Editor regarding Cunningham et al. 2020. Hypertension in Pregnancy, 40, pp. 133. (doi: 10.1080/10641955.2021.1899201)

McGettrick, M., MacLellan, A., McCaughey, P., Bagot, C., Brewis, M.J., Lang, N.N., Johnson, M.K., Church, A.C. (2021) Pulmonary thromboembolism in hospitalised patients with COVID-19: a retrospective national study of patients managed in critical care and ward environments in Scotland. BMJ Open, 11, (doi: 10.1136/bmjopen-2021-050281)

Wijkman, M. O., Malachias, M. V.B., Claggett, B. L., Cheng, S., Matsushita, K., Shah, A. M., Jhund, P. S., Coresh, J., Solomon, S. D., Vardeny, O. (2021) Resistance to antihypertensive treatment and long-term risk: The Atherosclerosis Risk in Communities study. Journal of Clinical Hypertension, 23, pp. 1887-1896. (doi: 10.1111/jch.14269)

Shoaib, A., Van Spall, H. G.C., Wu, J., Cleland, J. G.F., McDonagh, T. A., Rashid, M., Mohamed, M. O., Ahmed, F. Z., Deanfield, J., de Belder, M., Gale, C. P., Mamas, M. A. (2021) Substantial decline in hospital admissions for heart failure accompanied by increased community mortality during COVID-19 pandemic. European Heart Journal: Quality of Care and Clinical Outcomes, 7, pp. 378-387. (doi: 10.1093/ehjqcco/qcab040)

Shah, P., Pellicori, P., Hanning, I., Zhang, J., Clark, A. L., Bhandari, S. (2021) The effect of digoxin on renal function in patients with heart failure. BMC Nephrology, 22, (doi: 10.1186/s12882-021-02562-0)

Sykes, R., Briscoe, M., Krystofiak, T., Peck, O., Mangion, K., Berry, C. (2021) Type 2 myocardial infarction and myocardial injury: eligibility for novel medical therapy to de-risk clinical trials. Open Heart, 8, (doi: 10.1136/openhrt-2021-001633)

Ang, D. T. Y., Berry, C. (2021) What an interventionalist needs to know about INOCA. Interventional Cardiology Review, 16, (doi: 10.15420/icr.2021.16)

Sykes, R., Doherty, D., Mangion, K., Morrow, A., Berry, C. (2021) What an interventionalist needs to know about MI with non-obstructive coronary arteries. Interventional Cardiology Review, 16, (doi: 10.15420/icr.2021.10)

2020

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2019

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Budu-Aggrey, A. et al. (2019) Evidence of a causal relationship between body mass index and psoriasis: A mendelian randomization study. PLoS Medicine, 16, (doi: 10.1371/journal.pmed.1002739)

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MacKenzie, S. M., Nguyen Dinh Cat, A., van Kralingen, J., Davies, E. (2019) Aldosterone. Springer

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2018

Lemme, M., Ulmer, B. M., Lemoine, M. D., Zech, A. T.L., Flenner, F., Ravens, U., Reichenspurner, H., Rol-Garcia, M., Smith, G., Hansen, A., Christ, T., Eschenhagen, T. (2018) Atrial-like engineered heart tissue: an in vitro model of the human atrium. Stem Cell Reports, 11, pp. 1378-1390. (doi: 10.1016/j.stemcr.2018.10.008)

Ford, T. J., Stanley, B., Good, R., Rocchiccioli, P., McEntegart, M., Watkins, S., Eteiba, H., Shaukat, A., Lindsay, M., Robertson, K., Hood, S., McGeoch, R., McDade, R., Yii, E., Sidik, N., McCartney, P., Corcoran, D., Collison, D., Rush, C., McConnachie, A., Touyz, R., Oldroyd, K., Berry, C. (2018) Stratified medical therapy using invasive coronary function testing in angina: CorMicA trial. Journal of the American College of Cardiology, 72, pp. 2841-2855. (doi: 10.1016/j.jacc.2018.09.006)

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Rossitto, G., Touyz, R. M., Petrie, M. C., Delles, C. (2018) Much Ado about N...atrium: modelling tissuesodium as a highly sensitive marker of subclinicaland localized oedema. Clinical Science, 132, pp. 2609-2613. (doi: 10.1042/CS20180575)

Tromp, J., Ouwerkerk, W., Demissei, B.G., Anker, S.D., Cleland, J.G., Dickstein, K., Filippatos, G., van der Harst, P., Hillege, H.L., Lang, C.C., Metra, M., Ng, L.L., Ponikowski, P., Samani, N.J., van Veldhuisen, D.J., Zannad, F., Zwinderman, A.H., Voors, A.A., van der Meer, P. (2018) Novel endotypes in heart failure: effects on guideline-directed medical therapy. European Heart Journal, 39, pp. 4269-4276. (doi: 10.1093/eurheartj/ehy712)

Shiraishi, Y., Nagai, T., Kohsaka, S., Goda, A., Nagatomo, Y., Mizuno, A., Kohno, T., Rigby, A., Fukuda, K., Yoshikawa, T., Clark, A. L., Cleland, J. G.F. (2018) Outcome of hospitalised heart failure in Japan and the United Kingdom stratified by plasma N-terminal pro-B-type natriuretic peptide. Clinical Research in Cardiology, 107, pp. 1103-1110. (doi: 10.1007/s00392-018-1283-6)

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Hills, A. P., Misra, A., Gill, J. M.R., Byrne, N. M., Soares, M. J., Ramachandran, A., Palaniappan, L., Street, S. J., Jayawardena, R., Khunti, K., Arena, R. (2018) Public health and health systems: implications for the prevention and management of type 2 diabetes in south Asia. Lancet Diabetes and Endocrinology, 6, pp. 992-1002. (doi: 10.1016/S2213-8587(18)30203-1)

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Gillis, K., Stevens, K. K., Bell, E., Patel, R. K., Jardine, A. G., Morris, S. T.W., Schneider, M. P., Delles, C., Mark, P. B. (2018) Ascorbic acid lowers central blood pressure and asymmetric dimethylarginine in chronic kidney disease. Clinical Kidney Journal, 11, pp. 532-539. (doi: 10.1093/ckj/sfx158)

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Cosmi, F. et al. (2018) Treatment with insulin is associated with worse outcome in patients with chronic heart failure and diabetes. European Journal of Heart Failure, 20, pp. 888-895. (doi: 10.1002/ejhf.1146)

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Delles, C., Rankin, N. J., Boachie, C., McConnachie, A., Ford, I., Kangas, A., Soininen, P., Trompet, S., Mooijaart, S. P., Jukema, J. W., Zannad, F., Ala-Korpela, M., Salomaa, V., Havulinna, A. S., Welsh, P., Würtz, P., Sattar, N. (2018) Nuclear magnetic resonance-based metabolomics identifies phenylalanine as a novel predictor of incident heart failure hospitalisation: results from PROSPER and FINRISK 1997. European Journal of Heart Failure, 20, pp. 663-673. (doi: 10.1002/ejhf.1076)

Sokoreli, I., Pauws, S. C., Steyerberg, E. W., de Vries, G.-J., Riistama, J. M., Tesanovic, A., Kazmi, S., Pellicori, P., Cleland, J. G., Clark, A. L. (2018) Prognostic value of psychosocial factors for first and recurrent hospitalizations and mortality in heart failure patients: insights from the OPERA-HF study. European Journal of Heart Failure, 20, pp. 689-696. (doi: 10.1002/ejhf.1112)

Botha, S., Forde, L., MacNaughton, S., Shearer, R., Lindsay, R., Sattar, N., Morrison, D., Welsh, P., Logue, J. (2018) The effect of non-surgical weight management on weight and glycaemic control in people with type 2 diabetes: a comparison of interventional and non-interventional outcomes at three years. Diabetes, Obesity and Metabolism, 20, pp. 879-888. (doi: 10.1111/dom.13171)

Linde, C., Cleland, J. G.F., Gold, M. R., Daubert, J. C., Tang, A. S.L., Young, J. B., Sherfesee, L., Abraham, W. T. (2018) The interaction of sex, height, and QRS duration on the effects of cardiac resynchronization therapy on morbidity and mortality: an individual-patient data meta-analysis. European Journal of Heart Failure, 20, pp. 780-791. (doi: 10.1002/ejhf.1133)

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Malmo, V., Kelly, A., Garten, K. S., Stolen, T., Rolim, N. P. L., Wisloff, U., Smith, G., Loennechen, J. P. (2018) Aerobic interval training prevents age-dependent vulnerability to atrial fibrillation in rodents. Frontiers in Physiology, 9, (doi: 10.3389/fphys.2018.00206)

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Feng, Y.-M., Thijs, L., Zhang, Z.-Y., Yang, W.-Y., Huang, Q.-F., Wei, F.-F., Kuznetsova, T., Jennings, A.-M., Delles, C., Lennox, R., Verhamme, P., Dominiczak, A., Staessen, J. A. (2018) Glomerular function in relation to circulating adhesion molecules and inflammation markers in a general population. Nephrology Dialysis Transplantation, 33, pp. 426-435. (doi: 10.1093/ndt/gfx256)

Parsons, T. J., Sartini, C., Welsh, P., Sattar, N., Ash, S., Lennon, L. T., Wannamethee, S. G., Lee, I.-M., Whincup, P. H., Jefferis, B. J. (2018) Objectively measured physical activity and cardiac biomarkers: A cross sectional population based study in older men. International Journal of Cardiology, 254, pp. 322-327. (doi: 10.1016/j.ijcard.2017.11.003)

Gho, J. M.I.H., Schmidt, A. F., Pasea, L., Koudstaal, S., Pujades-Rodriguez, M., Denaxas, S., Shah, A. D., Patel, R. S., Gale, C. P., Hoes, A. W., Cleland, J. G., Hemingway, H., Asselbergs, F. W. (2018) An electronic health records cohort study on heart failure following myocardial infarction in England: incidence and predictors. BMJ Open, 8, (doi: 10.1136/bmjopen-2017-018331)

Taylor, R., Leslie, W. S., Barnes, A. C., Brosnahan, N., Thom, G., McCombie, L., Sattar, N., Welsh, P., Peters, C., Zhyzhneuskaya, S., Hollingsworth, K. G., Al-Mrabeh, A., Rodrigues, A. M., Rehackova, L., Adamson, A. J., Sniehotta, F. F., Mathers, J. C., Ross, H. M., McIlvenna, Y., Kean, S., Ford, I., McConnachie, A., Lean, M. E.J. (2018) Clinical and metabolic features of the randomised controlled Diabetes Remission Clinical Trial (DiRECT) cohort. Diabetologia, 61, pp. 589-598. (doi: 10.1007/s00125-017-4503-0)

Cameron, A. C., Bogie, J., Abdul-Rahim, A. H., Ahmed, N., Mazya, M., Mikulik, R., Hacke, W., Lees, K. R. (2018) Professional guideline versus product label selection for treatment with IV thrombolysis: an analysis from SITS registry. European Stroke Journal, 3, pp. 39-46. (doi: 10.1177/2396987317747737)

Mogensen, U. M., Køber, L., Jhund, P. S., Desai, A. S., Senni, M., Kristensen, S. L., Dukát, A., Chen, C.-H., Ramires, F., Lefkowitz, M. P., Prescott, M. F., Shi, V. C., Rouleau, J. L., Solomon, S. D., Swedberg, K., Packer, M., McMurray, J. J.V. (2018) Sacubitril/valsartan reduces serum uric acid concentration, an independent predictor of adverse outcomes in PARADIGM-HF. European Journal of Heart Failure, 20, pp. 514-522. (doi: 10.1002/ejhf.1056)

Stewart, R. A.H., Szalewska, D., Stebbins, A., Al-Khalidi, H. R., Cleland, J. G.H., Rynkiewicz, A., Drazner, M. H., White, H. D., Mark, D. B., Roy, A., Kosevic, D., Rajda, M., Jasinski, M., Leng, C. Y., Tungsubutra, W., Desvigne-Nickens, P., Velazquez, E. J., Petrie, M. C. (2018) Six-minute walk distance after coronary artery bypass grafting compared with medical therapy in ischaemic cardiomyopathy. Open Heart, 5, (doi: 10.1136/openhrt-2017-000752)

Gill, J. M.R., Hawari, N. S.A., Maxwell, D. J., Louden, D., Mourselas, N., Bunn, C., Gray, C. M., van der Ploeg, H. P., Hunt, K., Martin, A., Wyke, S., Mutrie, N. (2018) Validation of a novel device to measure and provide feedback on sedentary behavior. Medicine and Science in Sports and Exercise, 50, pp. 525-532. (doi: 10.1249/MSS.0000000000001458)

Petrie, M. C., Connelly, D. T., Gardner, R. S. (2018) Who needs an implantable cardioverter-defibrillator? Controversies and opportunities after DANISH. European Journal of Heart Failure, 20, pp. 413-416. (doi: 10.1002/ejhf.1135)

Velazquez, E. J., Petrie, M. C. (2018) CABG or PCI for diabetic patients with left ventricular dysfunction: closing in on the truth? Journal of the American College of Cardiology, 71, pp. 828-831. (doi: 10.1016/j.jacc.2018.01.014)

Chastin, S.F.M., Dontje, M.L., Skelton, D.A., Čukić, I., Shaw, R.J., Gill, J.M.R., Greig, C.A., Gale, C.R., Deary, I., Der, G., Dall, P.M. (2018) Systematic comparative validation of self-report measures of sedentary time against an objective measure of postural sitting (activPAL) International Journal of Behavioral Nutrition and Physical Activity, 15, (doi: 10.1186/s12966-018-0652-x)

ter Maaten, J. M., Voors, A. A., Damman, K., van der Meer, P., Anker, S. D., Cleland, J. G.F., Dickstein, K., Filippatos, G., van der Harst, P., Hillege, H. L., Lang, C. C., Metra, M., Navis, G., Ng, L., Ouwerkerk, W., Ponikowski, P., Samani, N. J., van Veldhuisen, D. J., Zannad, F., Zwinderman, A. H., de Borst, M. H. (2018) Fibroblast growth factor 23 is related to profiles indicating volume overload, poor therapy optimization and prognosis in patients with new-onset and worsening heart failure. International Journal of Cardiology, 253, pp. 84-90. (doi: 10.1016/j.ijcard.2017.10.010)

Lean, M. E.J. et al. (2018) Primary care-led weight management for remission of type 2 diabetes (DiRECT): an open-label, cluster-randomised trial. Lancet, 391, pp. 541-551. (doi: 10.1016/S0140-6736(17)33102-1)

Conrad, N., Judge, A., Tran, J., Mohseni, H., Hedgecott, D., Crespillo, A. P., Allison, M., Hemingway, H., Cleland, J. G., McMurray, J. J.V., Rahimi, K. (2018) Temporal trends and patterns in heart failure incidence: a population-based study of 4 million individuals. Lancet, 391, pp. 10-16. (doi: 10.1016/S0140-6736(17)32520-5)

Sala, L. et al. (2018) MUSCLEMOTION: a versatile open software tool to quantify cardiomyocyte and cardiac muscle contraction in vitro and in vivo. Circulation Research, 122, pp. e5-e16. (doi: 10.1161/CIRCRESAHA.117.312067)

Corcoran, D., Young, R., Cialdella, P., McCartney, P., Bajrangee, A., Hennigan, B., Collison, D., Carrick, D., Shaukat, A., Good, R., Watkins, S., McEntegart, M., Watt, J., Welsh, P., Sattar, N., McConnachie, A., Oldroyd, K.G., Berry, C. (2018) The effects of remote ischaemic preconditioning on coronary artery function in patients with stable coronary artery disease. International Journal of Cardiology, 252, pp. 24-30. (doi: 10.1016/j.ijcard.2017.10.082)

Currie, G., Delles, C. (2018) Blood pressure targets in the elderly. Journal of Hypertension, 36, pp. 234-236. (doi: 10.1097/HJH.0000000000001576)

Welsh, P. (2018) Correlating changes in metabolic status with arterial health: modest associations but any clinical implications? Hypertension, 71, pp. 227-228. (doi: 10.1161/HYPERTENSIONAHA.117.10595)

Adamson, P. D., Hunter, A., Williams, M. C., Shah, A. S.V., McAllister, D. A., Pawade, T. A., Dweck, M. R., Mills, N. L., Berry, C., Boon, N. A., Clark, E., Flather, M., Forbes, J., McLean, S., Roditi, G., van Beek, E. J.R., Timmis, A. D., Newby, D. E. (2018) Diagnostic and prognostic benefits of computed tomography coronary angiography using the 2016 National Institute for Health and Care Excellence guidance within a randomised trial. Heart, 104, pp. 207-214. (doi: 10.1136/heartjnl-2017-311508)

Rørth, R., Fosbøl, E. L., Mogensen, U. M., Kragholm, K., Numé, A.-k., Gislason, G. H.,, Jhund, P. S., Petrie, M. C., McMurray, J. J.V., Torp-Pedersen, C., Køber, L., Kristensen, S. L. (2018) Employment status at time of first hospitalization for heart failure is associated with death and rehospitalization for heart failure. European Journal of Heart Failure, 20, pp. 240-247. (doi: 10.1002/ejhf.1046)

Adamson, P. D., Hunter, A., Madsen, D. M., Shah, A. S.V., McAllister, D. A., Pawade, T. A., Williams, M. C., Berry, C., Boon, N. A., Flather, M., Forbes, J., McLean, S., Roditi, G., Timmis, A. D., van Beek, E. J.R., Dweck, M. R., Mickley, H., Mills, N. L., Newby, D. E. (2018) High-sensitivity cardiac troponin I and the diagnosis of coronary artery disease in patients with suspected angina pectoris. Circulation: Cardiovascular Quality and Outcomes, 11, (doi: 10.1161/CIRCOUTCOMES.117.004227)

Ferguson, L.D., Ntuk, U.E., Celis-Morales, C., Mackay, D.F., Pell, J.P., Gill, J.M.R., Sattar, N. (2018) Men across a range of ethnicities have a higher prevalence of diabetes: findings from a cross-sectional study of 500000 UK Biobank participants. Diabetic Medicine, 35, pp. 270-276. (doi: 10.1111/dme.13551)

Cleland, J. G.F. (2018) Physicians Addicted to Prescribing Aspirin-a Disorder Of Cardiologists (PAPA-DOC) Syndrome: the headache of nonevidence-based medicine for ischemic heart disease? JACC: Heart Failure, 6, pp. 168-171. (doi: 10.1016/j.jchf.2017.11.014)

Platz, E., Jhund, P. S., Claggett, B. L., Pfeffer, M. A., Swedberg, K., Granger, C. B., Yusuf, S., Solomon, S. D., McMurray, J. J. (2018) Prevalence and prognostic importance of precipitating factors leading to heart failure hospitalization: recurrent hospitalizations and mortality. European Journal of Heart Failure, 20, pp. 295-303. (doi: 10.1002/ejhf.901)

Nikolaidou, T., Pellicori, P., Zhang, J., Kazmi, S., Goode, K. M., Cleland, J. G., Clark, A. L. (2018) Prevalence, predictors, and prognostic implications of PR interval prolongation in patients with heart failure. Clinical Research in Cardiology, 107, pp. 108-119. (doi: 10.1007/s00392-017-1162-6)

Welsh, P., Kou, L., Yu, C., Anand, I., van Veldhuisen, D. J., Maggioni, A. P., Desai, A. S., Solomon, S. D., Pfeffer, M. A., Cheng, S., Gullestad, L., Aukrust, P., Ueland, T., Swedberg, K., Young, J. B., Kattan, M. W., Sattar, N., McMurray, J. J.V. (2018) Prognostic importance of emerging cardiac, inflammatory, and renal biomarkers in chronic heart failure patients with reduced ejection fraction and anaemia: RED-HF study. European Journal of Heart Failure, 20, pp. 268-277. (doi: 10.1002/ejhf.988)

Emmens, J. E., Jones, D. J.L., Cao, T. H., Chan, D. C.S., Romaine, S. P.R., Quinn, P. A., Anker, S. D., Cleland, J. G., Dickstein, K., Filippatos, G., Hillege, H. L., Lang, C. C., Ponikowski, P., Samani, N. J., van Veldhuisen, D. J., Zannad, F., Zwinderman, A. H., Metra, M., de Boer, R. A., Voors, A. A., Ng, L. L. (2018) Proteomic diversity of high-density lipoprotein explains its association with clinical outcome in patients with heart failure. European Journal of Heart Failure, 20, pp. 260-267. (doi: 10.1002/ejhf.1101)

Anderson, J. J., Darwis, N. D.M., Mackay, D. F., Celis-Morales, C., Lyall, D. M., Sattar, N., Gill, J. M.R., Pell, J. P. (2018) Red and processed meat consumption and breast cancer: UK Biobank cohort study and meta-analysis. European Journal of Cancer, 90, pp. 73-82. (doi: 10.1016/j.ejca.2017.11.022)

Ford, T. J., Corcoran, D., Berry, C. (2018) Stable coronary syndromes: pathophysiology, diagnostic advances and therapeutic need. Heart, 104, pp. 284-292. (doi: 10.1136/heartjnl-2017-311446)

Cotter, G., Metra, M., Davison, B. A., Jondeau, G., Cleland, J. G.F., Bourge, R. C., Milo, O., O'Connor, C. M., Parker, J. D., Torre-Amione, G., van Veldhuisen, D. J., Kobrin, I., Rainisio, M., Senger, S., Edwards, C., McMurray, J. J.V., Teerlink, J. R. (2018) Systolic blood pressure reduction during the first 24 h in acute heart failure admission: friend or foe? European Journal of Heart Failure, 20, pp. 317-322. (doi: 10.1002/ejhf.889)

Stoumpos, S., Lees, J., Welsh, P., Hund, M., Geddes, C. C., Nelson, S. M., Mark, P. B. (2018) The utility of anti-Müllerian hormone in women with chronic kidney disease, on haemodialysis and after kidney transplantation. Reproductive BioMedicine Online, 36, pp. 219-226. (doi: 10.1016/j.rbmo.2017.11.003)

Ouwerkerk, W., Zwinderman, A. H., Ng, L. L., Demissei, B., Hillege, H. L., Zannad, F., van Veldhuisen, D. J., Samani, N. J., Ponikowski, P., Metra, M., ter Maaten, J. M., Lang, C. C., van der Harst, P., Filippatos, G., Dickstein, K., Cleland, J. G., Anker, S. D., Voors, A. A. (2018) Biomarker-guided versus guideline-based treatment of patients with heart failure: results from BIOSTAT-CHF. Journal of the American College of Cardiology, 71, pp. 386-398. (doi: 10.1016/j.jacc.2017.11.041)

Feldman, T., Mauri, L., Kahwash, R., Litwin, S., Ricciardi, M. J., van der Harst, P., Penicka, M., Fail, P. S., Kaye, D. M., Petrie, M. C., Basuray, A., Hummel, S. L., Forde-McLean, R., Nielsen, C. D., Lilly, S., Massaro, J. M., Burkhoff, D., Shah, S. J. (2018) Transcatheter interatrial shunt device for the treatment of heart failure with preserved ejection fraction (REDUCE LAP-HF I [Reduce Elevated Left Atrial Pressure in Patients With Heart Failure]): A phase 2, randomized, sham-controlled trial. Circulation, 137, pp. 364-375. (doi: 10.1161/CIRCULATIONAHA.117.032094)

Gale, C. R. et al. (2018) The epigenetic clock and objectively measured sedentary and walking behavior in older adults: the Lothian Birth Cohort 1936. Clinical Epigenetics, 10, (doi: 10.1186/s13148-017-0438-z)

Cleland, J. G.F., Flather, M. D., Altman, D. G., Kotecha, D. (2018) Reply: an incomplete story. Journal of the American College of Cardiology, 71, pp. 105. (doi: 10.1016/j.jacc.2017.10.078)

McCarroll, C. S. et al. (2018) Runx1 deficiency protects against adverse cardiac remodeling after myocardial infarction. Circulation, 137, pp. 57-70. (doi: 10.1161/CIRCULATIONAHA.117.028911)

Cleland, J. G.F., Bunting, K. V., Flather, M. D., Altman, D. G., Holmes, J., Coats, A. J.S., Manzano, L., McMurray, J. J.V., Ruschitzka, F., van Veldhuisen, D. J., von Lueder, T. G., Böhm, M., Andersson, B., Kjekshus, J., Packer, M., Rigby, A. S., Rosano, G., Wedel, H., Hjalmarson, Å., Wikstrand, J., Kotecha, D. (2018) Beta-blockers for heart failure with reduced, mid-range, and preserved ejection fraction: an individual patient-level analysis of double-blind randomized trials. European Heart Journal, 39, pp. 26-35. (doi: 10.1093/eurheartj/ehx564)

Kristensen, S. L., Mogensen, U. M., Tarnesby, G., Gimpelewicz, C. R., Ali, M. A., Shao, Q., Chiang, Y., Jhund, P. S., Abraham, W. T., Dickstein, K., McMurray, J. J.V., Køber, L. (2018) Aliskiren alone or in combination with enalapril vs. enalapril among patients with chronic heart failure with and without diabetes: a subgroup analysis from the ATMOSPHERE trial. European Journal of Heart Failure, 20, pp. 136-147. (doi: 10.1002/ejhf.896)

Pellicori, P., Urbinati, A., Zhang, J., Joseph, A. C., Costanzo, P., Lukaschuk, E., Capucci, A., Cleland, J. G.F., Clark, A. L. (2018) Clinical and prognostic relationships of pulmonary artery to aorta diameter ratio in patients with heart failure: a cardiac magnetic resonance imaging study. Clinical Cardiology, 41, pp. 20-27. (doi: 10.1002/clc.22840)

Patel, N., Hellmuth, C., Uhl, O., Godfrey, K., Briley, A., Welsh, P., Pasupathy, D., Seed, P., Koletzko, B., Poston, L. (2018) Cord metabolic profiles In obese pregnant women; insights into offspring growth and body composition. Journal of Clinical Endocrinology and Metabolism, 103, pp. 346-355. (doi: 10.1210/jc.2017-00876)

Rørth, R., Fosbøl, E. L., Mogensen, U. M., Kragholm, K., Jhund, P. S., Petrie, M. C., Schou, M., Gislason, G. H., McMurray, J. J.V., Torp-Pedersen, C., Køber, L., Kristensen, S. L. (2018) Evidence based therapy and its association with workforce detachment following first hospitalization for heart failure. JACC: Heart Failure, 6, pp. 41-48. (doi: 10.1016/j.jchf.2017.09.019)

Beggs, S. A.S., Jhund, P. S., Jackson, C. E., McMurray, J. J.V., Gardner, R. S. (2018) Non-ischaemic cardiomyopathy, sudden death and implantable defibrillators: a review and meta-analysis. Heart, 104, pp. 144-150. (doi: 10.1136/heartjnl-2016-310850)

Muilwijk, M., Celis-Morales, C., Nicolaou, M., Snijder, M. B., Gill, J. M.R., van Valkengoed, I. G.M. (2018) Plasma cholesteryl ester fatty acids do not mediate the association of ethnicity with type 2 diabetes: results from the HELIUS study. Molecular Nutrition and Food Research, 62, (doi: 10.1002/mnfr.201700528)

Maznyczka, A. M., McCartney, P., Berry, C. (2018) Reference invasive tests of microvascular injury in myocardial infarction. BMJ Open, 104, pp. 90-92. (doi: 10.1136/heartjnl-2017-311695)

Lee, M. M.Y. et al. (2018) Routine Non-invasive vs Invasive Management in Patients With Prior CABG With a NSTE-ACS: a Randomised Controlled Trial. (doi: 10.1136/heartjnl-2018-BCIS.9)

Souteyrand, G., Valladier, M., Amabile, N., Derimay, F., Harbaoui, B., Leddet, P., Barnay, P., Malcles, G., Mulliez, A., Berry, C., Eschalier, R., Combaret, N., Motreff, P. (2018) Diagnosis and management of spontaneously recanalized coronary thrombus guided by optical coherence tomography ― lessons from the French “Lotus Root” registry ― Circulation Journal, 82, pp. 783-790. (doi: 10.1253/circj.cj-17-0810)

Lachaud, Q., MacQuaide, N., Burton, F., Smith, G. (2018) High-throughput study of rabbit ventricle action potential populations in MI model. Biophysical Journal, 114, pp. 625A. (doi: 10.1016/j.bpj.2017.11.3377)

Berry, C., Carberry, J., Mangion, K. (2018) How to mend a broken heart? JACC: Cardiovascular Imaging, 11, pp. 420-422. (doi: 10.1016/j.jcmg.2017.02.017)

McAllister, D. A., Read, S., Kerssens, J., Livingstone, S., McGurnaghan, S., Jhund, P., Petrie, J., Sattar, N., Fischbacher, C., Kristensen, S. L., McMurray, J., Colhoun, H. M., Wild, S. (2018) Incidence of hospitalisation for heart failure and case-fatality among 3.25 million people with and without diabetes. Circulation, 138, pp. 2774-2785. (doi: 10.1161/CIRCULATIONAHA.118.034986)

Rørth, R., Fosbøl, E. L., Kragholm, K., Mogensen, U. M., Jhund, P. S., Petrie, M. C., Torp-Pedersen, C., Gislason, G. H., McMurray, J. J.V., Køber, L., Kristensen, S. L. (2018) Initiation of domiciliary care and nursing home admission following first hospitalization for heart failure: a nationwide cohort study. Clinical Epidemiology, 10, pp. 917-930. (doi: 10.2147/CLEP.S164795)

Layland, J., Tong, D., Lee, M., Berry, C. (2018) ST and T-Wave Abnormality as Footprint of Myocardial Oedema in Non–ST-Elevation Myocardial Infarction. (doi: 10.1016/j.hlc.2018.06.515)

Bouabdallaoui, N. et al. (2018) Society of Thoracic Surgeons risk score and EuroSCORE-2 appropriately assess 30-day postoperative mortality in the STICH trial and a contemporary cohort of patients with left ventricular dysfunction undergoing surgical revascularization. Circulation: Heart Failure, 11, (doi: 10.1161/circheartfailure.118.005531)

Delles, C., Carrick, E., Graham, D., Nicklin, S. A. (2018) Utilising proteomics to understand and define hypertension: where are we and where do we go? Expert Review of Proteomics, 15, pp. 581-592. (doi: 10.1080/14789450.2018.1493927)

2017

Avtaar Singh, S. S., Das De, S., Spadaccio, C., Berry, C., Al-Attar, N. (2017) An overview of different methods of myocardial protection currently employed peri-transplantation. Vessel Plus, 1, pp. 213-229. (doi: 10.20517/2574-1209.2017.26)

Van't Veer, M., Pijls, N. H.J., Hennigan, B., Watkins, S., Ali, Z. A., De Bruyne, B., Zimmermann, F. M., van Nunen, L. X., Barbato, E., Berry, C., Oldroyd, K. G. (2017) Comparison of different diastolic resting indexes to iFR: are they all equal? Journal of the American College of Cardiology, 70, pp. 3088-3096. (doi: 10.1016/j.jacc.2017.10.066)

Ford, T. J., Berry, C., De Bruyne, B., Yong, A. C.S., Barlis, P., Fearon, W. F., Ng, M. K.C. (2017) Physiological predictors of acute coronary syndromes: emerging insights from the plaque to the vulnerable patient. JACC: Cardiovascular Interventions, 10, pp. 2539-2547. (doi: 10.1016/j.jcin.2017.08.059)

Berry, C., McClure, J. D., Oldroyd, K. G. (2017) Meta-analysis of death and myocardial infarction in the DEFINE-FLAIR and iFR-SWEDEHEART trials: a hypothesis generating note of caution. Circulation, 136, pp. 2389-2391. (doi: 10.1161/CIRCULATIONAHA.117.030430)

Lei, C. L., Wang, K., Clerx, M., Johnstone, R. H., Hortigon-Vinagre, M. P., Zamora, V., Allan, A., Smith, G. L., Gavaghan, D. J., Mirams, G. R., Polonchuk, L. (2017) Tailoring mathematical models to stem-cell derived cardiomyocyte lines can improve predictions of drug-induced changes to their electrophysiology. Frontiers in Physiology, 8, (doi: 10.3389/fphys.2017.00986)

Dybus, A., Paul, L., Wyke, S., Brewster, S., Gill, J. M.R., Ramsay, A., Campbell, E. (2017) Validation of smartphone step count algorithm used in STARFISH smartphone application. Technology and Health Care, 25, pp. 1157-1162. (doi: 10.3233/thc-170970)

Duncan, G., Firth, K., George, V., Hoang, M. D., Staniforth, A., Smith, G., Denning, C. (2017) Drug-mediated shortening of action potentials in LQTS2 human induced pluripotent stem cell-derived cardiomyocytes. Stem Cells and Development, 26, pp. 1695-1705. (doi: 10.1089/scd.2017.0172)

Celis-Morales, C. A., Petermann, F., Hui, L., Lyall, D. M., Iliodromiti, S., McLaren, J., Anderson, J., Welsh, P., Mackay, D. F., Pell, J. P., Sattar, N., Gill, J. M.R., Gray, S. R. (2017) Associations between diabetes and both cardiovascular disease and all-cause mortality are modified by grip strength: evidence from UK Biobank, a prospective population-based cohort study. Diabetes Care, 40, pp. 1710-1718. (doi: 10.2337/dc17-0921)

Kaye, D. M., Silvestry, F. E., Gustafsson, F., Cleland, J. G., van Veldhuisen, D. J., Ponikowski, P., Komtebedde, J., Nanayakkara, S., Burkhoff, D., Shah, S. J. (2017) Impact of atrial fibrillation on rest and exercise haemodynamics in heart failure with mid-range and preserved ejection fraction. European Journal of Heart Failure, 19, pp. 1690-1697. (doi: 10.1002/ejhf.930)

Hilfiker-Kleiner, D., Haghikia, A., Masuko, D., Nonhoff, J., Held, D., Libhaber, E., Petrie, M. C., Walker, N. L., Podewski, E., Berliner, D., Bauersachs, J., Sliwa, K. (2017) Outcome of subsequent pregnancies in patients with a history of peripartum cardiomyopathy. European Journal of Heart Failure, 19, pp. 1723-1728. (doi: 10.1002/ejhf.808)

Carberry, J., Carrick, D., Haig, C., Ahmed, N., Mordi, I., McEntegart, M., Petrie, M. C., Eteiba, H., Hood, S., Watkins, S., Lindsay, M., Davie, A., Mahrous, A., Ford, I., Sattar, N., Welsh, P., Radjenovic, A., Oldroyd, K. G., Berry, C. (2017) Persistence of infarct zone T2 hyperintensity at 6 months after acute ST-elevation myocardial infarction: incidence, pathophysiology and prognostic implications. Circulation: Cardiovascular Imaging, 10, (doi: 10.1161/CIRCIMAGING.117.006586)

Kristensen, S. L., Jhund, P. S., Lee, M. M.Y., Køber, L., Solomon, S. D., Granger, C. B., Yusuf, S., Pfeffer, M. A., Swedberg, K., McMurray, J. J.V. (2017) Prevalence of prediabetes and undiagnosed diabetes in patients with HFpEF and HFrEF and associated clinical outcomes. Cardiovascular Drugs and Therapy, 31, pp. 545-549. (doi: 10.1007/s10557-017-6754-x)

O'Neill, D.G., Riddell, A., Church, D.B., Owen, L., Brodbelt, D.C., Hall, J.L. (2017) Urinary incontinence in bitches under primary veterinary care in England: prevalence and risk factors. Journal of Small Animal Practice, 58, pp. 685-693. (doi: 10.1111/jsap.12731)

Yates, T., Zaccardi, F., Dhalwani, N. N., Davies, M. J., Bakrania, K., Celis-Morales, C. A., Gill, J. M.R., Franks, P. W., Khunti, K. (2017) Association of walking pace and handgrip strength with all-cause, cardiovascular, and cancer mortality: a UK biobank observational study. European Heart Journal, 38, pp. 3232-3240. (doi: 10.1093/eurheartj/ehx449)

Wang, G., Durussel, J., Shurlock, J., Mooses, M., Fuku, N., Bruinvels, G., Pedlar, C., Burden, R., Murray, A., Yee, B., Keenan, A., McClure, J. D., Sottas, P.-E., Pitsiladis, Y. P. (2017) Validation of whole-blood transcriptome signature during microdose recombinant human erythropoietin (rHuEpo) administration. BMC Genomics, 18, (doi: 10.1186/s12864-017-4191-7)

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Dierckx, R., Inglis, S. C., Clark, R. A., Prieto-Merino, D., Cleland, J. G.F. (2017) Telemedicine in heart failure: new insights from the Cochrane meta-analyses. European Journal of Heart Failure, 19, pp. 304-306. (doi: 10.1002/ejhf.759)

Currie, G., Delles, C. (2017) The future of "omics" in hypertension. Canadian Journal of Cardiology, 33, pp. 601-610. (doi: 10.1016/j.cjca.2016.11.023)

Carty, D. M., Doogan, F., Welsh, P., Dominiczak, A. F., Delles, C. (2017) Thyroid stimulating hormone (TSH) ≥2.5mU/l in early pregnancy: prevalence and subsequent outcomes. European Journal of Obstetrics and Gynecology and Reproductive Biology, 210, pp. 366-369. (doi: 10.1016/j.ejogrb.2017.01.048)

Graham-Brown, M. P.M., Rutherford, E., Levelt, E., March, D. S., Churchward, D. R., Stensel, D. J., McComb, C., Mangion, K., Cockburn, S., Berry, C., Moon, J. C., Mark, P. B., Burton, J. O., McCann, G. P. (2017) Native T1 mapping: inter-study, inter-observer and inter-center reproducibility in hemodialysis patients. Journal of Cardiovascular Magnetic Resonance, 19, (doi: 10.1186/s12968-017-0337-7)

Lyall, D. M., Celis-Morales, C. A., Anderson, J., Gill, J. M.R., Mackay, D. F., McIntosh, A. M., Smith, D. J., Deary, I. J., Sattar, N., Pell, J. P. (2017) Associations between single and multiple cardiometabolic diseases and cognitive abilities in 474 129 UK Biobank participants. European Heart Journal, 38, pp. 577-583. (doi: 10.1093/eurheartj/ehw528)

Mary, S., Kulkarni, M. J., Malakar, D., Joshi, S. R., Mehendale, S. S., Giri, A. P. (2017) Placental proteomics provides insights into pathophysiology of pre-eclampsia and predicts possible markers in plasma. Journal of Proteome Research, 16, pp. 1050-1060. (doi: 10.1021/acs.jproteome.6b00955)

Docherty, K. F., Campbell, R. T., Jhund, P., Petrie, M. C., McMurray, J. J.V. (2017) How robust are clinical trials in heart failure? European Heart Journal, 38, pp. 338-345. (doi: 10.1093/eurheartj/ehw427)

Emdin, C. A., Hsiao, A. J., Kiran, A., Conrad, N., Salimi-Khorshidi, G., Woodward, M., Anderson, S. G., Mohseni, H., McMurray, J. J.V., Cleland, J. G.F., Dargie, H., Hardman, S., McDonagh, T., Rahimi, K. (2017) Referral for specialist follow-up and its association with post-discharge mortality among patients with systolic heart failure (from the National Heart Failure Audit for England and Wales) American Journal of Cardiology, 119, pp. 440-444. (doi: 10.1016/j.amjcard.2016.10.021)

Koh-Tan, H.H. C., Dashti, M., Wang, T., Beattie, W., Mcclure, J., Young, B., Dominiczak, A. F., McBride, M. W., Graham, D. (2017) Dissecting the genetic components of a quantitative trait locus for blood pressure and renal pathology on rat chromosome 3. Journal of Hypertension, 35, pp. 319-329. (doi: 10.1097/HJH.0000000000001155)

Gastelurrutia, P., Lupón, J., Domingo, M., Stut, W., Dovancescu, S., Cleland, J., Frankenstein, L., Bayes-Genis, A. (2017) Potential role for clinical calibration to increase engagement with and application of home telemonitoring: a report from the HeartCycle programme. ESC Heart Failure, 4, pp. 66-70. (doi: 10.1002/ehf2.12104)

Zhang, J., Dierckx, R., Mohee, K., Clark, A. L., Cleland, J. G.F. (2017) Xanthine oxidase inhibition for the treatment of cardiovascular disease: an updated systematic review and meta-analysis. ESC Heart Failure, 4, pp. 40-45. (doi: 10.1002/ehf2.12112)

Delles, C., Husi, H. (2017) Systems biology approach in hypertension research. Springer

Mancini, S. J., White, A. D., Bijland, S., Rutherford, C., Graham, D., Richter, E. A., Viollet, B., Touyz, R. M., Palmer, T. M., Salt, I. P. (2017) Activation of AMP-activated protein kinase rapidly suppresses multiple pro-inflammatory pathways in adipocytes including IL-1 receptorassociated kinase-4 phosphorylation. Molecular and Cellular Endocrinology, 440, pp. 44-56. (doi: 10.1016/j.mce.2016.11.010)

Celis-Morales, C. A., Lyall, D. M., Anderson, J., Iliodromiti, S., Fan, Y., Ntuk, U. E., Mackay, D. F., Pell, J. P., Sattar, N., Gill, J. M.R. (2017) The association between physical activity and risk of mortality is modulated by grip strength and cardiorespiratory fitness: evidence from 498 135 UK-Biobank participants. European Heart Journal, 38, pp. 116-122. (doi: 10.1093/eurheartj/ehw249)

Gebhard, C., Rhéaume, E., Berry, C., Brand, G., Kernaleguen, A.-E., Théberge-Julien, G., Alam, M. A., Lee, C. Y.W., Boileau, L., Chabot-Blanchet, M., Guertin, M.-C., Lavoie, M.-A., Grégoire, J., Ibrahim, R., L'Allier, P., Tardif, J.-C. (2017) Beneficial effects of reconstituted high-density lipoprotein (rHDL) on circulating CD34+ cells in patients after an acute coronary syndrome. PLoS ONE, 12, (doi: 10.1371/journal.pone.0168448)

Cannon, J. A., Shen, L., Jhund, P. S., Kristensen, S. L., Køber, L., Chen, F., Gong, J., Lefkowitz, M. P., Rouleau, J. L., Shi, V. C., Swedberg, K., Zile, M. R., Solomon, S. D., Packer, M., McMurray, J. J.V. (2017) Dementia-related adverse events in PARADIGM-HF and other trials in heart failure with reduced ejection fraction. European Journal of Heart Failure, 19, pp. 129-137. (doi: 10.1002/ejhf.687)

Paul, L., Brewster, S., Wyke, S., McFadyen, A. K., Sattar, N., Gill, J., Dybus, A., Gray, C. M. (2017) Increasing physical activity in older adults using STARFISH, an interactive smartphone application (app); a pilot study. Journal of Rehabilitation and Assistive Technologies Engineering, 4, (doi: 10.1177/2055668317696236)

Streng, K. W., ter Maaten, J. M., Cleland, J. G.F., O’Connor, C. M., Davison, B. A., Metra, M., Givertz, M. M., Teerlink, J. R., Ponikowski, P., Bloomfield, D. M., Dittrich, H. C., Hillege, H. L., van Veldhuisen, D. J., Voors, A. A., van der Meer, P. (2017) Associations of body mass index with laboratory and biomarkers in patients with acute heart failure. Circulation: Heart Failure, 10, (doi: 10.1161/CIRCHEARTFAILURE.116.003350)

Kristensen, S. L., Mogensen, U. M., Jhund, P. S., Petrie, M. C., Preiss, D., Win, S., Køber, L., McKelvie, R. S., Zile, M. R., Anand, I. S., Komajda, M., Gottdiener, J. S., Carson, P. E., McMurray, J. J.V. (2017) Clinical and echocardiographic characteristics and cardiovascular outcomes according to diabetes status in patients with heart failure and preserved ejection fraction. A report from the Irbesartan in Heart Failure with Preserved Ejection Fraction Trial (I-Preserve) Circulation, 135, pp. 724-735. (doi: 10.1161/CIRCULATIONAHA.116.024593)

Blinova, K., Stohlman, J., Vicente, J., Chan, D., Johannesen, L., Hortigon-Vinagre, M. P., Zamora Rodriguez, V., Smith, G., Crumb, W. J., Pang, L., Lyn-Cook, B., Ross, J., Brock, M., Chvatal, S., Millard, D., Galeotti, L., Stockbridge, N., Strauss, D. G. (2017) Comprehensive translational assessment of human-induced pluripotent stem cell derived cardiomyocytes for evaluating drug-induced arrhythmias. Toxicological Sciences, 155, pp. 234-247. (doi: 10.1093/toxsci/kfw200)

Tromp, J., ter Maaten, J., Damman, K., O’Connor, C. M., Metra, M., Dittrich, H. C., Ponikowski, P., Teerlink, J. R., Cotter, G., Davison, B., Cleland, J. G.F., Givertz, M. M., Bloomfield, D. M., van der Wal, M. H.L., Jaarsma, T., van Veldhuisen, D. J., Hillege, H. L., Voors, A. A., van der Meer, P. (2017) Serum potassium levels and outcome in acute heart failure (data from the PROTECT and COACH trials) American Journal of Cardiology, 119, pp. 290-296. (doi: 10.1016/j.amjcard.2016.09.038)

Wyse, C. A., Celis Morales, C. A., Graham, N., Fan, Y., Ward, J., Curtis, A. M., Mackay, D., Smith, D. J., Bailey, M. E.S., Biello, S., Gill, J. M.R., Pell, J. P. (2017) Adverse metabolic and mental health outcomes associated with shiftwork in a population-based study of 277,168 workers in UK biobank. Annals of Medicine, 49, pp. 411-420. (doi: 10.1080/07853890.2017.1292045)

MacKenzie, S. M., Davies, E., Alvarez-Madrazo, S. (2017) Analysis of the aldosterone synthase (CYP11B2) and 11β-hydroxylase (CYP11B1) genes. Springer

Cameron, A. C., Lang, N. N., Touyz, R. M. (2017) Cardiovascular complications from cancer therapy: hypertension-focus on vascular endothelial growth factor inhibitors. Elesvier

Ridker, P. M. et al. (2017) Cardiovascular efficacy and safety of Bococizumab in high-risk patients. New England Journal of Medicine, 376, pp. 1527-1539. (doi: 10.1056/NEJMoa1701488)

Delles, C., Vanholder, R. (2017) Chronic kidney disease. Clinical Science, 131, pp. 225-226. (doi: 10.1042/CS20160624)

Celis-Morales, C., Lyall, D. M., Gray, S., Steell, L., Anderson, J., Iliodromiti, S., Welsh, P., Guo, Y., Petermann, F., Mackay, D. F., Bailey, M. E.S., Pell, J., Gill, J. M.R., Sattar, N. (2017) Dietary fat and total energy intake modifies the association of genetic profile risk score on obesity: evidence from 48 170 UK Biobank participants. International Journal of Obesity, 41, pp. 1761-1768. (doi: 10.1038/ijo.2017.169)

Cuthbert, J. J., Pellicori, P., Clark, A. L. (2017) Interatrial shunt devices for heart failure with normal ejection fraction: a technology update. Medical Devices: Evidence and Research, 10, pp. 123-132. (doi: 10.2147/mder.s113105)

Arain, F., Gullestad, L., Nymo, S., Kjekshus, J., Cleland, J. G.F., Michelsen, A., McMurray, J. J.V., Wikstrand, J., Aukrust, P., Ueland, T. (2017) Low YKL-40 in Chronic Heart Failure may predict beneficial effects of statins: Analysis from the Controlled Rosuvastatin Multinational Trial in Heart Failure (CORONA) Biomarkers, 22, pp. 261-267. (doi: 10.1080/1354750X.2016.1204003)

Pellicori, P., Carubelli, V. (2017) Terapia diuretica nell’insufficienza cardiaca cronica: evidenze, esperienze, prospettive = Diuretic treatment in patients with chronic heart failure: evidences, experiences, and current perspectives. Giornale Italiano di Cardiologia, 18, pp. 129-138. (doi: 10.1714/2663.27298)

Pellicori, P., Salekin, D., Pan, D., Clark, A. L. (2017) This patient is not breathing properly: is this COPD, heart failure, or neither? Expert Review of Cardiovascular Therapy, 15, pp. 389-396. (doi: 10.1080/14779072.2017.1317592)

2016

Torabi, A., Cleland, J. G.F., Sherwi, N., Atkin, P., Panahi, H., Kilpatrick, E., Thackray, S., Hoye, A., Alamgir, F., Goode, K., Rigby, A., Clark, A. L. (2016) Influence of case definition on incidence and outcome of acute coronary syndromes. Open Heart, 3, (doi: 10.1136/openhrt-2016-000487)

Fattah, C., Nather, K., McCarroll, C. S., Hortigon-Vinagre, M. P., Zamora Rodriguez, V., Flores-Munoz, M., McArthur, L., Zentilin, L., Giacca, M., Touyz, R. M., Smith, G. L., Loughrey, C. M., Nicklin, S. A. (2016) Gene therapy with Angiotensin-(1-9) preserves left ventricular systolic function after myocardial infarction. Journal of the American College of Cardiology, 68, pp. 2652-2666. (doi: 10.1016/j.jacc.2016.09.946)

Mangion, K., Gao, H., Mccomb, C., Carrick, D., Clerfond, G., Zhong, X., Luo, X., Haig, C., Berry, C. (2016) A novel method for estimating myocardial strain: assessment of deformation tracking against reference magnetic resonance methods in healthy volunteers. Scientific Reports, 6, (doi: 10.1038/srep38774)

Huethorst, E., Hortigon, M., Zamora-Rodriguez, V., Reynolds, P.M., Burton, F., Smith, G., Gadegaard, N. (2016) Enhanced human-induced pluripotent stem cell derived cardiomyocyte maturation using a dual microgradient substrate. ACS Biomaterials Science and Engineering, 2, pp. 2231-2239. (doi: 10.1021/acsbiomaterials.6b00426)

Kobayashi, Y., Johnson, N. P., Berry, C., De Bruyne, B., Gould, K. L., Jeremias, A., Oldroyd, K. G., Pijls, N. H.J., Fearon, W. F. (2016) The influence of lesion location on the diagnostic accuracy of adenosine-free coronary pressure wire measurements. JACC: Cardiovascular Interventions, 9, pp. 2390-2399. (doi: 10.1016/j.jcin.2016.08.041)

Teerlink, J. R., Felker, G. M., McMurray, J. J.V., Solomon, S. D., Adams, Jr., K. F., Cleland, J. G.F., Ezekowitz, J. A., Goudev, A., Macdonald, P., Metra, M., Mitrovic, V., Ponikowski, P., Serpytis, P., Spinar, J., Tomcsányi, J., Vandekerckhove, H. J., Voors, A. A., Monsalvo, M. L., Johnston, J., Malik, F. I., Honarpour, N. (2016) Chronic oral study of myosin activation to increase contractility in heart failure (COSMIC-HF): a phase 2, pharmacokinetic, randomised, placebo-controlled trial. Lancet, 388, pp. 2895-2903. (doi: 10.1016/S0140-6736(16)32049-9)

White, S. L., Lawlor, D. A., Briley, A. L., Godfrey, K. M., Nelson, S. M., Oteng-Ntim, E., Robson, S. C., Sattar, N., Seed, P. T., Vieira, M. C., Welsh, P., Whitworth, M., Poston, L., Pasupathy, D. (2016) Early antenatal prediction of gestational diabetes in obese women: development of prediction tools for targeted intervention. PLoS ONE, 11, (doi: 10.1371/journal.pone.0167846)

Carrick, D., Haig, C., Ahmed, N., Carberry, J., Teng Yue May, V., McEntegart, M., Petrie, M. C., Eteiba, H., Lindsay, M., Hood, S., Watkins, S., Davies, A., Abouzaid, A. M., Mordi, I., Ford, I., Radjenovic, A., Oldroyd, K. G., Berry, C. (2016) Comparative prognostic utility of indexes of microvascular function alone or in combination in patients with an acute ST-segment elevation myocardial infarction. Circulation, 134, pp. 1833-1847. (doi: 10.1161/CIRCULATIONAHA.116.022603)

Vegter, E. L., Schmitter, D., Hagemeijer, Y., Ovchinnikova, E. S., van der Harst, P., Teerlink, J. R., O'Connor, C. M., Metra, M., Davison, B. A., Bloomfield, D., Cotter, G., Cleland, J. G.F., Givertz, M. M., Ponikowski, P., van Veldhuisen, D. J., van der Meer, P., Berezikov, E., Voors, A. A., Khan, M. A.F. (2016) Use of biomarkers to establish potential role and function of circulating microRNAs in acute heart failure. International Journal of Cardiology, 224, pp. 231-239. (doi: 10.1016/j.ijcard.2016.09.010)

Pellicori, P., Cleland, J. G.F., Zhang, J., Kallvikbacka-Bennett, A., Urbinati, A., Shah, P., Kazmi, S., Clark, A. L. (2016) Cardiac dysfunction, congestion and loop diuretics: their relationship to prognosis in heart failure. Cardiovascular Drugs and Therapy, 30, pp. 599-609. (doi: 10.1007/s10557-016-6697-7)

Hawari, N. S.A., Al-Shayji, I., Wilson, J., Gill, J. M.R. (2016) Frequency of breaks in sedentary time and postprandial metabolic responses. Medicine and Science in Sports and Exercise, 48, pp. 2495-2502. (doi: 10.1249/MSS.0000000000001034)

Nagaraja, V., Ooi, S.-Y., Nolan, J., Large, A., De Belder, M., Ludman, P., Bagur, R., Curzen, N., Matsukage, T., Yoshimachi, F., Kwok, C. S., Berry, C., Mamas, M. A. (2016) Impact of incomplete percutaneous revascularization in patients With multivessel coronary artery disease: a systematic review and meta-analysis. Journal of the American Heart Association, 5, (doi: 10.1161/JAHA.116.004598)

Kaye, D. M., Hasenfuß, G., Neuzil, P., Post, M. C., Doughty, R., Trochu, J.-N., Kolodziej, A., Westenfeld, R., Penicka, M., Rosenberg, M., Walton, A., Muller, D., Walters, D., Hausleiter, J., Raake, P., Petrie, M. C., Bergmann, M., Jondeau, G., Feldman, T., van Veldhuisen, D. J., Ponikowski, P., Silvestry, F. E., Burkhoff, D., Hayward, C. (2016) One-year outcomes after transcatheter insertion of an interatrial shunt device for the management of heart failure with preserved ejection fraction. Circulation: Heart Failure, 9, (doi: 10.1161/CIRCHEARTFAILURE.116.003662)

Hortigon-Vinagre, M.P., Zamora, V., Burton, F.L., Green, J., Gintant, G.A., Smith, G.L. (2016) The use of ratiometric fluorescence measurements of the voltage sensitive dye Di-4-ANEPPS to examine action potential characteristics and drug effects on human induced pluripotent stem cell-derived cardiomyocytes. Toxicological Sciences, 154, pp. 320-331. (doi: 10.1093/toxsci/kfw171)

Napp, A. E. et al. (2016) Computed tomography versus invasive coronary angiography: design and methods of the pragmatic randomised multicentre DISCHARGE trial. European Radiology, 27, pp. 2957-2968. (doi: 10.1007/s00330-016-4620-z)

Inglis, S. C., Clark, R. A., Dierckx, R., Prieto-Merino, D., Cleland, J. G.F. (2016) Structured telephone support or non-invasive telemonitoring for patients with heart failure. Heart, 103, pp. 255-257. (doi: 10.1136/heartjnl-2015-309191)

Demissei, B. G., Postmus, D., Liu, L. C.Y., Cleland, J. G.F., O'Connor, C. M., Metra, M., Ponikowski, P., Teerlink, J. R., Cotter, G., Davison, B. A., Edwards, C., Givertz, M. M., Bloomfield, D. M., Dittrich, H. C., Voors, A. A., Hillege, H. L. (2016) Risk-based evaluation of efficacy of rolofylline in patients hospitalized with acute heart failure — Post-hoc analysis of the PROTECT trial. International Journal of Cardiology, 223, pp. 967-975. (doi: 10.1016/j.ijcard.2016.08.271)

Ferreira, J. P., Girerd, N., Pellicori, P., Duarte, K., Girerd, S., Pfeffer, M. A., McMurray, J. J.V., Pitt, B., Dickstein, K., Jacobs, L., Staessen, J. A., Butler, J., Latini, R., Masson, S., Mebazaa, A., Rocca, H. P. B.-L., Delles, C., Heymans, S., Sattar, N., Jukema, J. W., Cleland, J. G.F., Zannad, F., Rossignol, P. (2016) Renal function estimation and Cockroft–Gault formulas for predicting cardiovascular mortality in population-based, cardiovascular risk, heart failure and post-myocardial infarction cohorts: the Heart ‘OMics’ in AGEing (HOMAGE) and the high-risk myocardial infarction database initiatives. BMC Medicine, 14, (doi: 10.1186/s12916-016-0731-2)

Rutherford, C., Speirs, C., Williams, J. J.L., Ewart, M.-A., Mancini, S. J., Hawley, S. A., Delles, C., Viollet, B., Costa-Pereira, A. P., Baillie, G. S., Salt, I. P., Palmer, T. M. (2016) Phosphorylation of Janus kinase 1 (JAK1) by AMP-activated protein kinase (AMPK) links energy sensing to anti-inflammatory signaling. Science Signaling, 9, (doi: 10.1126/scisignal.aaf8566)

Jhund, P. S. (2016) Geographic variation in heart failure - a matter of celebration or condemnation? European Journal of Heart Failure, 18, pp. 1329-1330. (doi: 10.1002/ejhf.652)

Weinberger, F., Breckwoldt, K., Pecha, S., Kelly, A., Geertz, B., Starbatty, J., Yorgan, T., Cheng, K.-H., Lessmann, K., Stolen, T., Scherrer-Crosbie, M., Smith, G., Reichenspurner, H., Hansen, A., Eschenhagen, T. (2016) Cardiac repair in guinea pigs with human engineered heart tissue from induced pluripotent stem cells. Science Translational Medicine, 8, pp. 363ra148-363ra148. (doi: 10.1126/scitranslmed.aaf8781)

Bekfani, T., Pellicori, P., Morris, D. A., Ebner, N., Valentova, M., Steinbeck, L., Wachter, R., Elsner, S., Sliziuk, V., Schefold, J. C., Sandek, A., Doehner, W., Cleland, J. G.F., Lainscak, M., Anker, S. D., von Haehling, S. (2016) Sarcopenia in patients with heart failure with preserved ejection fraction: impact on muscle strength, exercise capacity and quality of life. International Journal of Cardiology, 222, pp. 41-46. (doi: 10.1016/j.ijcard.2016.07.135)

Petrie, M. C., Jhund, P. S., She, L., Adlbrecht, C., Doenst, T., Panza, J. A., Hill, J. A., Lee, K. L., Rouleau, J. L., Prior, D. L., Ali, I. S., Maddury, J., Golba, K. S., White, H. D., Carson, P., Chrzanowski, L., Romanov, A., Miller, A. B., Velazquez, E. J. (2016) Ten-year outcomes after coronary artery bypass grafting according to age in patients with heart failure and left ventricular systolic dysfunction: an analysis of the extended follow-up of the STICH Trial (Surgical Treatment for Ischemic Heart Failure) Circulation, 134, pp. 1314-1324. (doi: 10.1161/CIRCULATIONAHA.116.024800)

Desai, A. S., Jhund, P. S. (2016) After TOPCAT: what to do now in heart failure with preserved ejection fraction. European Heart Journal, 37, pp. 3135-3140. (doi: 10.1093/eurheartj/ehw114)

Lyall, D. M., Celis-Morales, C., Ward, J., Iliodromiti, S., Anderson, J. J., Gill, J. M.R., Smith, D. J., Ntuk, U. E., Mackay, D. F., Holmes, M. V., Sattar, N., Pell, J. P. (2016) Body-mass index and cardiometabolic disease: a Mendelian randomisation study of UK Biobank Participants. Lancet, 388, pp. S9-S9. (doi: 10.1016/S0140-6736(16)32245-0)

Hennigan, B., Oldroyd, K. G., Berry, C., Johnson, N., McClure, J., McCartney, P., McEntegart, M. B., Eteiba, H., Petrie, M. C., Rocchiccioli, P., Good, R., Lindsay, M. M., Hood, S., Watkins, S. (2016) Discordance between resting and hyperemic indices of coronary stenosis severity: the VERIFY 2 study (a comparative study of resting coronary pressure gradient, instantaneous wave-free ratio and fractional flow reserve in an unselected population referred for invasive angiography) Circulation: Cardiovascular Interventions, 9, (doi: 10.1161/CIRCINTERVENTIONS.116.004016)

Welsh, P., Tuckwell, K., McInnes, I. B., Sattar, N. (2016) Effect of IL-6 receptor blockade on high-sensitivity troponin T and NT-proBNP in rheumatoid arthritis. Atherosclerosis, 254, pp. 167-171. (doi: 10.1016/j.atherosclerosis.2016.10.016)

Preiss, D., Rankin, N., Welsh, P., Holman, R.R., Kangas, A.J., Soininen, P., Würtz, P., Ala-Korpela, M., Sattar, N. (2016) Effect of metformin therapy on circulating amino acids in a randomized trial: the CAMERA study. Diabetic Medicine, 33, pp. 1569-1574. (doi: 10.1111/dme.13097)

Sirker, A., Kwok, C. S., Kotronias, R., Bagur, R., Bertrand, O., Butler, R., Berry, C., Nolan, J., Oldroyd, K., Mamas, M. (2016) Influence of access site choice for cardiac catheterization on risk of adverse neurological events: A systematic review and meta-analysis. American Heart Journal, 181, pp. 107-119. (doi: 10.1016/j.ahj.2016.06.027)

Mangion, K., Clerfond, G., Mccomb, C., Carrick, D., Rauhalammi, S. M., McClure, J., Corcoran, D. S., Woodward, R., Orchard, V., Radjenovic, A., Zhong, X., Berry, C. (2016) Myocardial strain in healthy adults across a broad age range as revealed by cardiac magnetic resonance imaging at 1.5 and 3.0T: associations of myocardial strain with myocardial region, age, and sex. Journal of Magnetic Resonance Imaging, 44, pp. 1197-1205. (doi: 10.1002/jmri.25280)

Ahmed, N., Carberry, J., Teng, V., Carrick, D., Berry, C. (2016) Risk assessment in patients with an acute ST-elevation myocardial infarction. Journal of Comparative Effectiveness Research, 5, pp. 581-593. (doi: 10.2217/cer-2016-0017)

Small, H. Y., Nosalski, R., Morgan, H., Beattie, E., Guzik, T., Graham, D., Delles, C. (2016) The role of tumor necrosis factor-α and natural killer cells in uterine artery function and pregnancy outcome in the stroke prone spontaneously hypertensive rat. Hypertension, 68, pp. 1298-1307. (doi: 10.1161/HYPERTENSIONAHA.116.07933)

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Berry, C., Carrick, D., Haig, C., Oldroyd, K. G. (2016) “Waves of Edema” seem implausible. Journal of the American College of Cardiology, 67, pp. 1868-1869. (doi: 10.1016/j.jacc.2015.11.073)

Abdul-Rahim, A. H., MacIsaac, R. L., Jhund, P. S., Petrie, M. C., Lees, K. R., McMurray, J. J.V. (2016) Efficacy and safety of digoxin in patients with heart failure and reduced ejection fraction according to diabetes status: An analysis of the Digitalis Investigation Group (DIG) trial. International Journal of Cardiology, 209, pp. 310-316. (doi: 10.1016/j.ijcard.2016.02.074)

Wan Sulaiman, W.N., Caslake, M.J., Delles, C., Karlsson, H., Mulder, M.T., Graham, D., Freeman, D.J. (2016) Does high-density lipoprotein protect vascular function in healthy pregnancy? Clinical Science, 130, pp. 491-497. (doi: 10.1042/cs20150475)

Carrick, D., Haig, C., Rauhalammi, S., Ahmed, N., Mordi, I., McEntegart, M., Petrie, M. C., Eteiba, H., Hood, S., Lindsay, M., Mahrous, A., Ford, I., Tzemos, N., Sattar, N., Welsh, P., Radjenovic, A., Oldroyd, K. G., Berry, C. (2016) Prognostic significance of infarct core pathology revealed by quantitative non-contrast in comparison to contrast cardiac magnetic resonance imaging in reperfused ST-elevation myocardial infarction survivors. European Heart Journal, 37, pp. 1044-1059. (doi: 10.1093/eurheartj/ehv372)

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Diver, L. A., MacKenzie, S. M., Fraser, R., McManus, F., Freel, E. M., Alvarez-Madrazo, S., McClure, J. D., Friel, E. C., Hanley, N. A., Dominiczak, A. F., Caulfield, M. J., Munroe, P. B., Connell, J. M., Davies, E. (2016) Common polymorphisms at the CYP17A1 locus associate with steroid phenotype: support for blood pressure genome-wide association study signals at this locus. Hypertension, 67, pp. 724-732. (doi: 10.1161/HYPERTENSIONAHA.115.06925)

Paul, L., Wyke, S., Brewster, S., Sattar, N., Gill, J. M.R., Alexander, G., Rafferty, D., McFadyen, A. K., Ramsay, A., Dybus, A. (2016) Increasing physical activity in stroke survivors using STARFISH, an interactive mobile phone application: a pilot study. Topics in Stroke Rehabilitation, 23, pp. 170-177. (doi: 10.1080/10749357.2015.1122266)

Eisele, N., Albrecht, C., Mistry, H. D., Dick, B., Baumann, M., Surbek, D., Currie, G., Delles, C., Mohaupt, M. G., Escher, G., Gennari-Moser, C. (2016) Placental expression of the angiogenic placental growth factor is stimulated by both aldosterone and simulated starvation. Placenta, 40, pp. 18-24. (doi: 10.1016/j.placenta.2016.02.004)

Ovchinnikova, E. S. et al. (2016) Signature of circulating microRNAs in patients with acute heart failure. European Journal of Heart Failure, 18, pp. 414-423. (doi: 10.1002/ejhf.332)

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Wilson, R., Aung, H., Ju, X., Paterson, C., Sayer, R., McIntyre, A., Going, J., Irvine, R., Berry, C. (2016) Optical coherence tomography: an experimental validation for vascular imaging of saphenous vein bypass grafts. Biomedical Physics and Engineering Express, 2, (doi: 10.1088/2057-1976/2/2/025002)

Cuba Gyllensten, I., Bonomi, A. G., Goode, K. M., Reiter, H., Habetha, J., Amft, O., Cleland, J. G.F. (2016) Early indication of decompensated heart failure in patients on home-telemonitoring: a comparison of prediction algorithms based on daily weight and noninvasive transthoracic bio-impedance. JMIR Medical Informatics, 4, (doi: 10.2196/medinform.4842)

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Currie, G., Delles, C., Touyz, R. M., Staessen, J. A., Dominiczak, A. F., Jennings, G. L. R., Wang, J.-G. (2016) A woman with treatment-resistant hypertension. Hypertension, 67, pp. 243-250. (doi: 10.1161/HYPERTENSIONAHA.115.06756)

Bhandari, S., Ives, N., Brettell, E. A., Valente, M., Cockwell, P., Topham, P. S., Cleland, J. G.F., Khwaja, A., El Nahas, M. (2016) Multicentre randomized controlled trial of angiotensin-converting enzyme inhibitor/angiotensin receptor blocker withdrawal in advanced renal disease: the STOP-ACEi trial. Nephrology Dialysis Transplantation, 31, pp. 255-261. (doi: 10.1093/ndt/gfv346)

Welsh, P., Hart, C., Papacosta, O., Preiss, D., McConnachie, A., Murray, H., Ramsay, S., Upton, M., Watt, G., Whincup, P., Wannamethee, G., Sattar, N. (2016) Prediction of cardiovascular disease risk by cardiac biomarkers in 2 United Kingdom cohort studies: does utility depend on risk thresholds for treatment? Hypertension, 2016, pp. 309-315. (doi: 10.1161/HYPERTENSIONAHA.115.06501)

Small, H. Y., Currie, G. E., Delles, C. (2016) Prostasin, proteases, and preeclampsia. Journal of Hypertension, 34, pp. 193-195. (doi: 10.1097/hjh.0000000000000828)

Carrick, D., Haig, C., Rauhalammi, S., Clerfond, G., Ahmed, N., Mordi, I., McEntegart, M., Petrie, M., Eteiba, H., Hood, S., Watkins, S., Lindsay, M. M., Mahrous, A., Welsh, P., Sattar, N., Ford, I., Oldroyd, K., Radjenovic, A., Berry, C. (2016) Temporal evolution of myocardial hemorrhage and edema in patients after acute ST-elevation myocardial infarction: pathophysiologic insights and clinical implications. Journal of the American Heart Association, 5, (doi: 10.1161/JAHA.115.002834)

Watt, J., Kennedy, S., Ahmed, N., Hayhurst, J., McClure, J. D., Berry, C., Wadsworth, R. M., Oldroyd, K. G. (2016) The relationship between oxidised LDL, endothelial progenitor cells and coronary endothelial function in patients with CHD. Open Heart, 3, (doi: 10.1136/openhrt-2015-000342)

Mangion, K., Gao, H., Radjenovic, A., Luo, X., Haig, C., Berry, C. (2016) Pixel-tracking derived strain using the GlasgowHeart Method. Journal of Cardiovascular Magnetic Resonance, 18, (doi: 10.1186/1532-429X-18-S1-P9)

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Bakrania, K., Edwardson, C. L., Bodicoat, D. H., Esliger, D. W., Gill, J. M. R., Kazi, A., Velayudhan, L., Sinclair, A. J., Sattar, N., Biddle, S. J. H., Khunti, K., Davies, M., Yates, T. (2016) Associations of mutually exclusive categories of physical activity and sedentary time with markers of cardiometabolic health in English adults: a cross-sectional analysis of the Health Survey for England. BMC Public Health, 16, (doi: 10.1186/s12889-016-2694-9)

Zhang, J., Hobkirk, J., Carroll, S., Pellicori, P., Clark, A. L., Cleland, J. G.F. (2016) Exploring quality of life in patients with and without heart failure. International Journal of Cardiology, 202, pp. 676-684. (doi: 10.1016/j.ijcard.2015.09.076)

Ahmed, N., Layland, J., Carrick, D., Petrie, M. C., McEntegart, M., Eteiba, H., Hood, S., Lindsay, M., Watkins, S., Davie, A., Mahrous, A., Carberry, J., Teng, V., McConnachie, A., Curzen, N., Oldroyd, K. G., Berry, C. (2016) Safety of guidewire-based measurement of fractional flow reserve and the index of microvascular resistance using intravenous adenosine in patients with acute or recent myocardial infarction. International Journal of Cardiology, 202, pp. 305-310. (doi: 10.1016/j.ijcard.2015.09.014)

Small, H. Y., Morgan, H., Beattie, E., Griffin, S., Indahl, M., Delles, C., Graham, D. (2016) Abnormal uterine artery remodelling in the stroke prone spontaneously hypertensive rat. Placenta, 37, pp. 34-44. (doi: 10.1016/j.placenta.2015.10.022)

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Kristensen, S. L., Preiss, D., Jhund, P. S., Squire, I., Cardoso, J. S., Merkely, B., Martinez, F., Starling, R. C., Desai, A. S., Lefkowitz, M. P., Rizkala, A. R., Rouleau, J. L., Shi, V. C., Solomon, S. D., Swedberg, K., Zile, M. R., McMurray, J. J.V., Packer, M. (2016) Risk related to pre–diabetes mellitus and diabetes mellitus in heart failure with reduced ejection fraction: insights from prospective comparison of ARNI with ACEI to determine impact on global mortality and morbidity in heart failure trial. Circulation: Heart Failure, 9, (doi: 10.1161/CIRCHEARTFAILURE.115.002560)

Cowie, M. R., Bax, J., Bruining, N., Cleland, J. G.F., Koehler, F., Malik, M., Pinto, F., van der Velde, E., Vardas, P. (2016) e-Health: a position statement of the European Society of Cardiology. European Heart Journal, 37, pp. 63-66. (doi: 10.1093/eurheartj/ehv416)

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Olsen, M. H., Angell, S. Y., Asma, S., Boutouyrie, P., Burger, D., Chirinos, J. A., Damasceno, A., Delles, C., Gimenez-Roqueplo, A.-P., Hering, D., López-Jaramillo, P., Martinez, F., Perkovic, V., Rietzschel, E. R., Schillaci, G., Schutte, A. E., Scuteri, A., Sharman, J. E., Wachtell, K., Wang, J. G. (2016) A call to action and a lifecourse strategy to address the global burden of raised blood pressure on current and future generations: the Lancet Commission on hypertension. Lancet, 388, pp. 2665-2712. (doi: 10.1016/S0140-6736(16)31134-5)

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McCallum, J. E., Mackenzie, A. E., Divorty, N., Clarke, C., Delles, C., Milligan, G., Nicklin, S. A. (2016) G protein-coupled receptor 35 mediates human saphenous vein vascular smooth muscle cell migration and endothelial cell proliferation. Journal of Vascular Research, 52, pp. 383-395. (doi: 10.1159/000444754)

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Carrick, D., Haig, C., Watkins, S., Ahmed, N., McEntegart, M., Petrie, M. C., Eteiba, H., Hood, S., Watkins, S., Lindsay, M. M., Davie, A., Mahrous, A., Mordi, I., Rauhalammi, S., Sattar, N., Welsh, P., Radjenovic, A., Ford, I., Oldroyd, K., Berry, C. (2016) Myocardial hemorrhage after acute reperfused ST-segment-elevation myocardial infarction. Circulation: Cardiovascular Imaging, 9, (doi: 10.1161/CIRCIMAGING.115.004148)

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2015

Cameron, A. C., Touyz, R. M., Lang, N. N. (2015) Vascular complications of cancer chemotherapy. Canadian Journal of Cardiology, 32, pp. 852-862. (doi: 10.1016/j.cjca.2015.12.023)

Cleland, J. G.F., Mareev, Y. (2015) CRT for heart failure and ESRD: more trials or more thought needed? Journal of the American College of Cardiology, 66, pp. 2630-2632. (doi: 10.1016/j.jacc.2015.10.022)

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Berry, C., Corcoran, D., Hennigan, B., Watkins, S., Layland, J., Oldroyd, K. G. (2015) Fractional flow reserve-guided management in stable coronary disease and acute myocardial infarction: recent developments. European Heart Journal, 36, pp. 3155-3164. (doi: 10.1093/eurheartj/ehv206)

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Mareev, Y., Cleland, J. G.F. (2015) Should β-blockers be used in patients with heart failure and atrial fibrillation? Clinical Therapeutics, 37, pp. 2215-2224. (doi: 10.1016/j.clinthera.2015.08.017)

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Frankenstein, L., Fröhlich, H., Cleland, J. G.F. (2015) Multidisciplinary approach for patients hospitalized with heart failure. Revista Española de Cardiología (English Edition), 68, pp. 885-891. (doi: 10.1016/j.rec.2015.05.008)

Zoccarato, A. et al. (2015) Cardiac hypertrophy is inhibited by a local pool of cAMP regulated by phosphodiesterase 2. Circulation Research, 117, pp. 707-719. (doi: 10.1161/CIRCRESAHA.114.305892)

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Platz, E., Jhund, P. S., Campbell, R. T., McMurray, J. (2015) Assessment and prevalence of pulmonary oedema in contemporary acute heart failure trials: a systematic review. European Journal of Heart Failure, 17, pp. 906-916. (doi: 10.1002/ejhf.321)

Fisher, M., Petrie, M., Ambery, P., Donaldson, J., McMurray, J. J.V., Ye, J. (2015) Cardiovascular safety of albiglutide in the Harmony programme: a meta-analysis. Lancet Diabetes and Endocrinology, 3, pp. 697-703. (doi: 10.1016/s2213-8587(15)00233-8)

Pellicori, P., Clark, A. L. (2015) Clinical trials update from the European Society of Cardiology-Heart Failure meeting 2015: AUGMENT-HF, TITRATION, STOP-HF, HARMONIZE, LION HEART, MOOD-HF, and renin-angiotensin inhibitors in patients with heart and renal failure. European Journal of Heart Failure, 17, pp. 979-983. (doi: 10.1002/ejhf.340)

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Campbell, R. T., Petrie, C. J., Payne, A. R., McEntegart, M. (2015) Elderly woman presenting after a collapse. Annals of Emergency Medicine, 66, pp. 338-345. (doi: 10.1016/j.annemergmed.2014.10.017)

Dierckx, R., Cleland, J. G.F., Pellicori, P., Zhang, J., Goode, K., Putzu, P., Boyalla, V., Clark, A. L. (2015) If home telemonitoring reduces mortality in heart failure, is this just due to better guideline-based treatment? Journal of Telemedicine and Telecare, 21, pp. 331-339. (doi: 10.1177/1357633X15574947)

Mordi, I., Radjenovic, A., Stanton, T., Gardner, R., McPhaden, A., Carrick, D., Berry, C., Tzemos, N. (2015) Prevalence and prognostic significance of lipomatous metaplasia in poatients with prior myocardial infarction. JACC: Cardiovascular Imaging, 8, pp. 1111-1112. (doi: 10.1016/j.jcmg.2014.07.024)

Stut, W., Deighan, C., Cleland, J. G., Jaarsma, T. (2015) Adherence to self-care in patients with heart failure in the HeartCycle study. Patient Preference and Adherence, 9, pp. 1195-1206. (doi: 10.2147/PPA.S88482)

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Jackson, C. E., Haig, C., Welsh, P., Dalzell, J. R., Tsorlalis, I. K., McConnachie, A., Preiss, D., McInnes, I. B., Sattar, N., Petrie, M. C., Gardner, R. S., McMurray, J. J.V. (2015) Combined free light chains are novel predictors of prognosis in heart failure. JACC: Heart Failure, 3, pp. 618-625. (doi: 10.1016/j.jchf.2015.03.014)

Abdalrahaman, N., Mccomb, C., Foster, J. E., McLean, J., Lindsay, R. S., McClure, J., McMillan, M., Drummond, R., Gordon, D., McKay, G. A., Shaikh, M. G., Perry, C. G., Ahmed, S. F. (2015) Deficits in trabecular bone microarchitecture in young women with Type 1 diabetes mellitus. Journal of Bone and Mineral Research, 30, pp. 1386-1393. (doi: 10.1002/jbmr.2465)

Schanstra, J.P. et al. (2015) Diagnosis and prediction of CKD progression by assessment of urinary peptides. Journal of the American Society of Nephrology, 26, pp. 1999-2010. (doi: 10.1681/asn.2014050423)

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Menni, C. et al. (2015) Metabolomic identification of a novel pathway of blood pressure regulation involving hexadecanedioate. Hypertension, 66, pp. 422-429. (doi: 10.1161/HYPERTENSIONAHA.115.05544)

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Cleland, J. G.F., Mareev, Y., Linde, C. (2015) Reflections on EchoCRT: sound guidance on QRS duration and morphology for CRT? European Heart Journal, 36, pp. 1948-1951. (doi: 10.1093/eurheartj/ehv264)

Askevold, E. T., Gullestad, L., Nymo, S., Kjekshus, J., Yndestad, A., Latini, R., Cleland, J. G.F., McMurray, J. J.V., Aukrust, P., Ueland, T. (2015) Secreted frizzled related protein 3 in chronic heart failure: analysis from the controlled rosuvastatin multinational trial in heart failure (CORONA) PLoS ONE, 10, (doi: 10.1371/journal.pone.0133970)

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Garg, S., Anderson, S.G., Oldroyd, K., Berry, C., Emdin, C.A., Peters, S.A.E., West, N.E.J., Kelly, D., Balachandran, K., McDonald, J., Singh, R., Devadathan, S., Redwood, S., Ludman, P.F., Rahimi, K., Woodward, M. (2015) Outcomes of percutaneous coronary intervention performed at offsite versus onsite surgical centers in the United Kingdom. Journal of the American College of Cardiology, 66, pp. 363-372. (doi: 10.1016/j.jacc.2015.05.052)

Raphael, C. E., Finegold, J. A., Barron, A. J., Whinnett, Z. I., Mayet, J., Linde, C., Cleland, J. G.F., Levy, W. C., Francis, D. P. (2015) The effect of duration of follow-up and presence of competing risk on lifespan-gain from implantable cardioverter defibrillator therapy: who benefits the most? European Heart Journal, 36, pp. 1676-1688. (doi: 10.1093/eurheartj/ehv102)

MacDonald, M. R., She, L., Doenst, T., Binkley, P. F., Rouleau, J. L., Tan, R.-S., Lee, K. L., Miller, A. B., Sopko, G., Szalewska, D., Waclawiw, M. A., Dabrowski, R., Castelvecchio, S., Adlbrecht, C., Michler, R. E., Oh, J. K., Velazquez, E. J., Petrie, M. C. (2015) Clinical characteristics and outcomes of patients with and without diabetes in the Surgical Treatment for Ischemic Heart Failure (STICH) trial. European Journal of Heart Failure, 17, pp. 725-734. (doi: 10.1002/ejhf.288)

Mentz, R. J., Metra, M., Cotter, G., Milo, O., McKendry, C., Chiswell, K., Davison, B. A., Cleland, J. G.F., Bloomfield, D. M., Dittrich, H. C., Fiuzat, M., Ponikowski, P., Givertz, M. M., Voors, A. A., Teerlink, J. R., O'Connor, C. M. (2015) Early vs. late worsening heart failure during acute heart failure hospitalization: insights from the PROTECT trial. European Journal of Heart Failure, 17, pp. 697-706. (doi: 10.1002/ejhf.308)

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Ferrari, R., Böhm, M., Cleland, J. G.F., Paulus, W. J.S., Pieske, B., Rapezzi, C., Tavazzi, L. (2015) Heart failure with preserved ejection fraction: uncertainties and dilemmas. European Journal of Heart Failure, 17, pp. 665-671. (doi: 10.1002/ejhf.304)

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Pellicori, P., Kallvikbacka-Bennett, A., Dierckx, R., Zhang, J., Putzu, P., Cuthbert, J., Boyalla, V., Shoaib, A., Clark, A. L., Cleland, J. G.F. (2015) Prognostic significance of ultrasound-assessed jugular vein distensibility in heart failure. Heart, 101, pp. 1149-1158. (doi: 10.1136/heartjnl-2015-307558)

Zannad, F., Greenberg, B., Cleland, J. G.F., Gheorghiade, M., van Veldhuisen, D. J., Mehra, M. R., Anker, S. D., Byra, W. M., Fu, M., Mills, R. M. (2015) Rationale and design of a randomized, double-blind, event-driven, multicentre study comparing the efficacy and safety of oral rivaroxaban with placebo for reducing the risk of death, myocardial infarction or stroke in subjects with heart failure and significant coronary artery disease following an exacerbation of heart failure: the COMMANDER HF trial. European Journal of Heart Failure, 17, pp. 735-742. (doi: 10.1002/ejhf.266)

Johnson, N.P., Johnson, D.T., Kirkeeide, R.L., Berry, C., De Bruyne, B., Fearon, W.F., Oldroyd, K.G., Pijls, N.H.J., Gould, K.L. (2015) Repeatability of fractional flow reserve despite variations in systemic and coronary hemodynamics. JACC: Cardiovascular Interventions, 8, pp. 1018-1027. (doi: 10.1016/j.jcin.2015.01.039)

Petrie, M.C., Boyle, J.G., McKay, G.A. (2015) Use of metformin in chronic kidney disease should continue to be based on common sense in the absence of an evidence base. Diabetic Medicine, 32, pp. 981-982. (doi: 10.1111/dme.12709)

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McArthur, L., Chilton, L., Smith, G. L., Nicklin, S. A. (2015) Electrical consequences of cardiac myocyte: fibroblast coupling. Biochemical Society Transactions, 43, pp. 513-518. (doi: 10.1042/BST20150035)

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Ferguson, L., Sattar, N. (2015) Endothelial function measures: not for clinical prime time? International Journal of Clinical Practice, 69, pp. 624-625. (doi: 10.1111/ijcp.12642)

Inglis, S. C., Conway, A., Cleland, J. G.F., Clark, R. A. (2015) Is age a factor in the success or failure of remote monitoring in heart failure? Telemonitoring and structured telephone support in elderly heart failure patients. European Journal of Cardiovascular Nursing, 14, pp. 248-255. (doi: 10.1177/1474515114530611)

GHAFOURI, K., Cooney, J., Bedford, D. K., Wilson, J., Caslake, M. J., Gill, J. M.R. (2015) Moderate exercise increases affinity of large very low density lipoproteins for hydrolysis by lipoprotein lipase. Journal of Clinical Endocrinology and Metabolism, 100, pp. 2205-2213. (doi: 10.1210/jc.2015-1196)

Goncalves, A., Jhund, P.S., Claggett, B., Shah, A.M., Konety, S., Butler, K., Kitzman, D.W., Rosamond, W., Fuchs, F.D., Solomon, S.D. (2015) Relationship between alcohol consumption and cardiac structure and function in the elderly: the atherosclerosis tisk in communities study. Circulation: Cardiovascular Imaging, 8, (doi: 10.1161/circimaging.114.002846)

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Preiss, D. et al. (2015) The effect of statin therapy on heart failure events: a collaborative meta-analysis of unpublished data from major randomized trials. European Heart Journal, 36, pp. 1536-1546. (doi: 10.1093/eurheartj/ehv072)

Dalzell, J. R., Rocchiccioli, J. P., Weir, R. A.P., Jackson, C. E., Padmanabhan, N., Gardner, R. S., Petrie, M. C., McMurray, J. J.V. (2015) The emerging potential of the apelin-APJ system in heart failure. Journal of Cardiac Failure, 21, pp. 489-498. (doi: 10.1016/j.cardfail.2015.03.007)

Dakin, R. S., Parker, A. L., Delles, C., Nicklin, S. A., Baker, A. H. (2015) Efficient transduction of primary vascular cells by the rare adenovirus serotype 49 vector. Human Gene Therapy, 26, pp. 312-319. (doi: 10.1089/hum.2015.019)

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Costanzo, P., Cleland, J. G.F., Pellicori, P., Clark, A. L., Hepburn, D., Kilpatrick, E. S., Perrone-Filardi, P., Zhang, J., Atkin, S. L. (2015) The obesity paradox in type 2 diabetes mellitus: relationship of body mass index to prognosis: a cohort study. Annals of Internal Medicine, 162, pp. 610-618. (doi: 10.7326/M14-1551)

Kukulski, T., She, L., Racine, N., Gradinac, S., Panza, J. A., Velazquez, E. J., Chan, K., Petrie, M. C., Lee, K. L., Pellikka, P. A., Romanov, A., Biernat, J., Rouleau, J. L., Batlle, C., Rogowski, J., Ferrazzi, P., Zembala, M., Oh, J. K. (2015) Implication of right ventricular dysfunction on long-term outcome in patients with ischemic cardiomyopathy undergoing coronary artery bypass grafting with or without surgical ventricular reconstruction. Journal of Thoracic and Cardiovascular Surgery, 149, pp. 1312-1321. (doi: 10.1016/j.jtcvs.2014.09.117)

Filippatos, G., Khan, S. S., Ambrosy, A. P., Cleland, J. G.F., Collins, S. P., Lam, C. S.P., Angermann, C. E., Ertl, G., Dahlström, U., Hu, D., Dickstein, K., Perrone, S. V., Ghadanfar, M., Bermann, G., Noe, A., Schweizer, A., Maier, T., Gheorghiade, M. (2015) International REgistry to assess medical practice with lOngitudinal obseRvation for Treatment of Heart Failure (REPORT-HF): rationale for and design of a global registry. European Journal of Heart Failure, 17, pp. 527-533. (doi: 10.1002/ejhf.262)

Davison, B. A., Metra, M., Cotter, G., Massie, B. M., Cleland, J. G.F., Dittrich, H. C., Edwards, C., Filippatos, G., Givertz, M. M., Greenberg, B., Ponikowski, P., Voors, A. A., O’Connor, C. M., Teerlink, J. R. (2015) Worsening heart failure following admission for acute heart failure: a pooled analysis of the PROTECT and RELAX-AHF studies. JACC: Heart Failure, 3, pp. 395-403. (doi: 10.1016/j.jchf.2015.01.007)

Ravassa, S., Kuznetsova, T., Varo, N., Thijs, L., Delles, C., Dominiczak, A., Díez, J., Staessen, J. A. (2015) Biomarkers of cardiomyocyte injury and stress identify left atrial and left ventricular remodelling and dysfunction: a population-based study. International Journal of Cardiology, 185, pp. 177-185. (doi: 10.1016/j.ijcard.2015.03.046)

Smith, G. L., MacQuaide, N. (2015) The direct actions of flecainide on the human cardiac ryanodine receptor: keeping open the debate on the mechanism of action of local anesthetics in CPVT. Circulation Research, 116, pp. 1284-1286. (doi: 10.1161/CIRCRESAHA.115.306298)

Goncalves, A., Claggett, B., Jhund, P. S., Rosamond, W., Deswal, A., Aguilar, D., Shah, A. M., Cheng, S., Solomon, S. D. (2015) Alcohol consumption and risk of heart failure: the Atherosclerosis Risk in Communities Study. European Heart Journal, 36, pp. 939-945. (doi: 10.1093/eurheartj/ehu514)

Ghouri, N., Purves, D., Deans, K. A., Logan, G., McConnachie, A., Wilson, J., Gill, J. M. R., Sattar, N. (2015) An investigation of two-dimensional ultrasound carotid plaque presence and intima media thickness in middle-aged South Asian and European men living in the United Kingdom. PLoS ONE, 10, (doi: 10.1371/journal.pone.0123317)

Feinstein, M. J., Jhund, P., Kang, J., Ning, H., Maggioni, A., Wikstrand, J., Kjekshus, J., Tavazzi, L., McMurray, J., Lloyd-Jones, D. M. (2015) Do statins reduce the risk of myocardial infarction in patients with heart failure? A pooled individual-level reanalysis of CORONA and GISSI-HF. European Journal of Heart Failure, 17, pp. 434-441. (doi: 10.1002/ejhf.247)

McInnes, I. B., Thompson, L., Giles, J. T., Bathon, J. M., Salmon, J. E., Beaulieu, A. D., Codding, C. E., Carlson, T. H., Delles, C., Lee, J. S., Sattar, N. (2015) Effect of interleukin-6 receptor blockade on surrogates of vascular risk in rheumatoid arthritis: MEASURE, a randomised, placebo-controlled study. Annals of the Rheumatic Diseases, 74, pp. 694-702. (doi: 10.1136/annrheumdis-2013-204345)

Mischak, H., Delles, C., Vlahou, A., Vanholder, R. (2015) Proteomic biomarkers in kidney disease: issues in development and implementation. Nature Reviews Nephrology, 11, pp. 221-232. (doi: 10.1038/nrneph.2014.247)

Abdul-Rahim, A. H., Perez, A.-C., Fulton, R. L., Jhund, P. S., Latini, R., Tognoni, G., Wikstrand, J., Kjekshus, J., Lip, G. Y.H., Maggioni, A. P., Tavazzi, L., Lees, K. R., McMurray, J. (2015) Risk of stroke in chronic heart failure patients without atrial fibrillation: analysis of the controlled rosuvastatin in multinational trial heart failure (corona) and the gruppo italiano per lo studio della sopravvivenza nell'insufficienza cardiaca-heart failure (gissi-hf) trials. Circulation, 131, pp. 1486-1494. (doi: 10.1161/CIRCULATIONAHA.114.013760)

Cleland, J. G.F., Butcher, C. (2015) When is it appropriate to withdraw cardiac resynchronization therapy? Guesses and evidence. JACC: Heart Failure, 3, pp. 337-339. (doi: 10.1016/j.jchf.2015.01.003)

Pellicori, P., Zhang, J., Lukaschuk, E., Joseph, A. C., Bourantas, C. V., Loh, H., Bragadeesh, T., Clark, A. L., Cleland, J. G.F. (2015) Left atrial function measured by cardiac magnetic resonance imaging in patients with heart failure: clinical associations and prognostic value. European Heart Journal, 36, pp. 733-742. (doi: 10.1093/eurheartj/ehu405)

Vazir, A., Claggett, B., Jhund, P., Castagno, D., Skali, H., Yusuf, S., Swedberg, K., Granger, C.B., McMurray, J.J.V., Pfeffer, M. A., Solomon, S.D. (2015) Prognostic importance of temporal changes in resting heart rate in heart failure patients: an analysis of the CHARM program. European Heart Journal, 36, pp. 669-675. (doi: 10.1093/eurheartj/ehu401)

Jankowska, E. A., Wojtas, K., Kasztura, M., Mazur, G., Butrym, A., Kalicinska, E., Rybinska, I., Skiba, J., von Haehling, S., Doehner, W., Anker, S. D., Banasiak, W., Cleland, J. G.F., Ponikowski, P. (2015) Bone marrow iron depletion is common in patients with coronary artery disease. International Journal of Cardiology, 182, pp. 517-522. (doi: 10.1016/j.ijcard.2014.10.006)

Metra, M., Cotter, G., El-Khorazaty, J., Davison, B. A., Milo, O., Carubelli, V., Bourge, R. C., Cleland, J. G., Jondeau, G., Krum, H., O'Connor, C. M., Parker, J. D., Torre-Amione, G., van Veldhuisen, D. J., Rainisio, M., Kobrin, I., McMurray, J. J., Teerlink, J. R. (2015) Acute heart failure in the elderly: differences in clinical characteristics, outcomes, and prognostic factors in the VERITAS Study. Journal of Cardiac Failure, 21, pp. 179-88. (doi: 10.1016/j.cardfail.2014.12.012)

Skogstrand, T., Leh, S., McClure, J., Dashti, M., Iversen, B. M., Graham, D., McBride, M., Hultström, M. (2015) Identification of a common molecular pathway in hypertensive renal damage. Journal of Hypertension, 33, pp. 584-596. (doi: 10.1097/HJH.0000000000000395)

Pellicori, P., Cleland, J. G.F. (2015) Is the epidemic of heart disease really over or just evolving? American Journal of Medicine, 128, pp. e17. (doi: 10.1016/j.amjmed.2014.09.018)

Campbell, R. T., Jackson, C., Wright, A., Gardner, R. S., Ford, I., Davidson, P. M., Denvir, M. A., Hogg, K. J., Johnson, M. J., Petrie, M. C., McMurray, J. J. V. (2015) Palliative care needs in patients hospitalized with heart failure (PCHF) study: rationale and design. ESC Heart Failure, 2, pp. 25-36. (doi: 10.1002/ehf2.12027)

Dierckx, R., Cleland, J. G.F., Parsons, S., Putzu, P., Pellicori, P., Dicken, B., Boyalla, V., Clark, A. L. (2015) Prescribing patterns to optimize heart rate: analysis of 1,000 consecutive outpatient appointments to a single heart failure clinic over a 6-month period. JACC: Heart Failure, 3, pp. 224-230. (doi: 10.1016/j.jchf.2014.11.003)

Khand, A. U., Chew, P. G., Douglas, H., Jones, J., Jan, A., Cleland, J.G.F. (2015) The effect of carvedilol on b-type natriuretic peptide and cardiac function in patients with heart failure and persistent atrial fibrillation. Cardiology, 130, pp. 153-158. (doi: 10.1159/000368746)

Pellicori, P., Cleland, J. G.F. (2015) Update on management of heart failure with preserved ejection fraction. Current Opinion in Cardiology, 30, pp. 173-178. (doi: 10.1097/HCO.0000000000000152)

McManus, F., Fraser, R., Davies, E., Connell, J.M.C., Freel, E.M. (2015) Plasma steroid profiling and response to trophins to illustrate intra-adrenal dynamics. Journal of Endocrinology, 224, pp. 149-157. (doi: 10.1530/JOE-14-0561)

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Kristensen, S. L., Jhund, P. S., Køber, L., Preiss, D., Kjekshus, J., McKelvie, R. S., Zile, M. R., Anand, I. S., Wikstrand, J. G.F., Wedel, H., Komajda, M., Carson, P. E., Cleland, J., McMurray, J. J.V. (2015) Comparison of outcomes after hospitalization for worsening heart failure, myocardial infarction, and stroke in patients with heart failure and reduced and preserved ejection fraction. European Journal of Heart Failure, 17, pp. 169-176. (doi: 10.1002/ejhf.211)

Boyalla, V., Putzu, P., Dierckx, R., Clark, A. L., Pellicori, P. (2015) Patent Ductus Arteriosus in older adults: incidental finding or relevant pathology? Journal of the American Geriatrics Society, 63, pp. 409-411. (doi: 10.1111/jgs.13256)

Layland, J. et al. (2015) Fractional flow reserve vs. angiography in guiding management to optimize outcomes in non-ST-segment elevation myocardial infarction: the British Heart Foundation FAMOUS-NSTEMI randomized trial. European Heart Journal, 36, pp. 100-111. (doi: 10.1093/eurheartj/ehu338)

Ghouri, I. A., Kelly, A., Burton, F. L., Smith, G. L., Kemi, O. J. (2015) 2-photon excitation fluorescence microscopy enables deeper high-resolution imaging of voltage and Ca2+in intact mice, rat, and rabbit hearts. Journal of Biophotonics, 8, pp. 112-123. (doi: 10.1002/jbio.201300109)

Metra, M., Mentz, R. J., Chiswell, K., Bloomfield, D. M., Cleland, J. G.F., Cotter, G., Davison, B. A., Dittrich, H. C., Fiuzat, M., Givertz, M. M., Lazzarini, V., Mansoor, G. A., Massie, B. M., Ponikowski, P., Teerlink, J. R., Voors, A. A., O'Connor, C. M. (2015) Acute heart failure in elderly patients: worse outcomes and differential utility of standard prognostic variables. Insights from the PROTECT trial. European Journal of Heart Failure, 17, pp. 109-118. (doi: 10.1002/ejhf.207)

Malkova, D., Gill, J. M.R., Manthou, E. (2015) Effect of exercise programmes with aerobic exercise sessions of similar intensity but different frequency and duration on health related measures in overweight women. Journal of Physical Activity and Health, 12, pp. 80-86. (doi: 10.1123/jpah.2013-0047)

Dickstein, K., Normand, C., Anker, S.D., Auricchio, A., Lundqvist Blomstrom, C., Bogale, N., Cleland, J., Filippatos, G., Gasparini, M., Gitt, A., Hindricks, G., Kuck, K.-H., Ponikowski, P., Stellbrink, C., Ruschitzka, F., Linde, C. (2015) European cardiac resynchronization therapy survey II: rationale and design. Europace, 17, pp. 137-141. (doi: 10.1093/europace/euu312)

Kristensen, S. L. L., Køber, L., Jhund, P. S., Solomon, S. D., Kjekshus, J., McKelvie, R. S., Zile, M. R., Granger, C. B., Wikstrand, J., Komajda, M., Carson, P. E., Pfeffer, M. A., Swedberg, K., Wedel, H., Yusuf, S., McMurray, J. J. V. (2015) International geographic variation in event rates in trials of heart failure with preserved and reduced ejection fraction. Circulation, 131, pp. 43-53. (doi: 10.1161/CIRCULATIONAHA.114.012284)

McArthur, L., Johnston, L., Sattar, N., Logue, J., Welsh, P. (2015) Preanalytical study of fetuin-A: effect of sample type, processing speed and freeze-thaw cycles. Annals of Clinical Biochemistry, 52, pp. 165-168. (doi: 10.1177/0004563214529550)

Ripley, D. P., Brown, J., Everett, C. C., Bijsterveld, P., Walker, S., Sculpher, M., McCann, G. P., Berry, C., Plein, S., Greenwood, J. P. (2015) Rationale and design of the Clinical Evaluation of Magnetic Resonance Imaging in Coronary heart disease 2 trial (CE-MARC 2): a prospective, multicenter, randomized trial of diagnostic strategies in suspected coronary heart disease. American Heart Journal, 169, pp. 17-24.e1. (doi: 10.1016/j.ahj.2014.10.008)

Dierckx, R., Pellicori, P., Cleland, J.G.F., Clark, A.L. (2015) Telemonitoring in heart failure: Big Brother watching over you. Heart Failure Reviews, 20, pp. 107-116. (doi: 10.1007/s10741-014-9449-4)

Layland, J., Rauhalammi, S., Watkins, S., Ahmed, N., McClure, J., Lee, M. M.Y., Carrick, D., O’Donnell, A., Sood, A., Petrie, M. C., Teng Yue May, V., Eteiba, H., Lindsay, M., McEntegart, M., Oldroyd, K. G., Radjenovic, A., Berry, C. (2015) Assessment of fractional flow reserve in patients with recent Non–ST-Segment–Elevation Myocardial Infarction. Circulation: Cardiovascular Interventions, 8, (doi: 10.1161/circinterventions.114.002207)

Musunuru, K., Hickey, K. T., Al-Khatib, S. M., Delles, C., Fornage, M., Fox, C. S., Frazier, L., Gelb, B. D., Herrington, D. M., Lanfear, D. E., Rosand, J. (2015) Basic concepts and potential applications of genetics and genomics for cardiovascular and stroke clinicians: a scientific statement from the American Heart Association. Circulation: Cardiovascular Genetics, 8, pp. 216-242. (doi: 10.1161/HCG.0000000000000020)

Pellicori, P., Costanzo, P. (2015) Betabloccanti in pazienti con scompenso cardiaco e fibrillazione atriale = [Betablockers in patients with heart failure and atrial fibrillation] Giornale italiano di cardiologia, 16, pp. 613-616. (doi: 10.1714/2066.22428)

Welsh, P., Preiss, D., Touyz, R. M. (2015) Biomarkers of hypertension and cardiovascular disease. Royal Society of Chemistry

Welsh, P., Preiss, D., Tsiropoulou, S., Rios, F. J., Harvey, A., Dulak-Lis, M. G., Montezano, A. C., Touyz, R. M. (2015) Biomarkers of vascular inflammation and cardiovascular disease. Springer

Newby, D. et al. (2015) CT coronary angiography in patients with suspected angina due to coronary heart disease (SCOT-HEART): an open-label, parallel-group, multicentre trial. Lancet, 385, pp. 2383-2391. (doi: 10.1016/S0140-6736(15)60291-4)

Badar, A. A., Perez-Moreno, A. C., Hawkins, N. M., Jhund, P. S., Brunton, A. P.T., Anand, I. S., McKelvie, R. S., Komajda, M., Zile, M. R., Carson, P. E., Gardner, R. S., Petrie, M. C., McMurray, J. J.V. (2015) Clinical characteristics and outcomes of patients with coronary artery disease and angina. Circulation: Heart Failure, 8, pp. 717-724. (doi: 10.1161/CIRCHEARTFAILURE.114.002024)

Corcoran, D., Berry, C., Oldroyd, K. (2015) Current frontiers in the clinical research of coronary physiology. Interventional Cardiology, 7, pp. 97-106.

Campbell, R. T., Jhund, P. S., Dalzell, J. R., Cannon, J., Mordi, I., Sonecki, P., Tzemos, N. (2015) Diagnosis and resolution of loeffler endocarditis secondary to eosinphilic granulomatosis with polyangiitis demonstrated by cardiac magnetic resonance-t2 mapping. Circulation, 131, pp. 114-117. (doi: 10.1161/CIRCULATIONAHA.114.011291)

Pellicori, P., Kaur, K., Clark, A. L. (2015) Fluid management in patients with chronic heart failure. Cardiac Failure Review, 1, pp. 90-95. (doi: 10.15420/cfr.2015.1.2.90)

Gao, H., Qi, N., Ma, X., Griffith, B. E., Berry, C., Luo, X. (2015) Fluid-structure interaction model of human mitral valve within left ventricle. Springer International Publishing

Lopez, L. M., Hill, W. D., Harris, S. E., Valdes Hernandez, M., Munoz Maniega, S., Bastin, M. E., Bailey, E., Smith, C., McBride, M., McClure, J., Graham, D., Dominiczak, A., Yang, Q., Fornage, M., Ikram, M. A., Debette, S., Launer, L., Bis, J. C., Schmidt, R., Seshadri, S., Porteous, D. J., Starr, J., Deary, I. J., Wardlaw, J. M. (2015) Genes from a translational analysis support a multifactorial nature of white matter hyperintensities. Stroke, 46, pp. 341-347. (doi: 10.1161/STROKEAHA.114.007649)

Mistry, H.D., Eisele, N., Escher, G., Dick, B., Surbek, D., Delles, C., Currie, G., Schlembach, D., Mohaupt, M.G., Gennari-Moser, C. (2015) Gestation-specific reference intervals for comprehensive spot urinary steroid hormone metabolite analysis in normal singleton pregnancy and 6 weeks postpartum. Reproductive Biology and Endocrinology, 13, (doi: 10.1186/s12958-015-0100-6)

Ferguson, L.D., Logue, J. (2015) Has IMPROVE-IT improved cardiovascular outcome? Journal of the Royal College of Physicians of Edinburgh, 45, pp. 215-217.

Jhund, P. S. (2015) Heart failure management: continuing to fail or signs of success? Cardiovascular Drugs and Therapy, 29, pp. 5-6. (doi: 10.1007/s10557-015-6574-9)

Gao, H., Berry, C., Luo, X. (2015) Image-derived human left ventricular modelling with fluid-structure interaction. Springer International Publishing

Aitken, E., Geddes, C., Thomson, P., Kasthuri, R., Chandramohan, M., Berry, C., Kingsmore, D. (2015) Immediate access arteriovenous grafts versus tunnelled central venous catheters: study protocol for a randomised controlled trial. Trials, 16, (doi: 10.1186/s13063-015-0556-x)

Dalzell, J. R., Cannon, J. A., Simpson, J., Gardner, R. S., Petrie, M. C. (2015) Improving outcomes in peripartum cardiomyopathy. Expert Review of Cardiovascular Therapy, 13, pp. 665-671. (doi: 10.1586/14779072.2015.1040767)

Mangion, K., Carrick, D., Payne, A., McClure, J., Mason, M., Petrie, M., McEntegart, M., Eteiba, H., Oldroyd, K., Berry, C. (2015) Infarct burden following multivessel PCI vs. infarct-only PCI in patients with acute STEMI: the Glasgow PRAMI CMR sub-study. Journal of Cardiovascular Magnetic Resonance, 17, (doi: 10.1186/1532-429X-17-S1-O9)

Souteyrand, G., Amabile, N., Combaret, N., Hammas, S., Prati, F., Berry, C., Pereira, B., Lusson, J.-R., Caussin, C., Motreff, P. (2015) Invasive management without stents in selected acute coronary syndrome patients with a large thrombus burden: a prospective study of optical coherence tomography guided treatment decisions. EuroIntervention, 11, pp. 895-904. (doi: 10.4244/eijy14m07_18)

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Mangion, K., Carrick, D., Payne, A. R., McClure, J., Mason, M., Petrie, M., McEntegart, M., Eteiba, H., Oldroyd, K. G., Berry, C. (2015) Left ventricular outcomes following multivessel PCI vs. infarct artery-only PCI in patients with acute STEMI: the Glasgow PRAMI CMR sub-study. Journal of Cardiovascular Magnetic Resonance, 17, (doi: 10.1186/1532-429X-17-S1-P104)

MacCannell, K.A., Chilton, L., Smith, G.L., Giles, W.R. (2015) Mathematical simulations of sphingosine-1-phosphate actions on mammalian ventricular myofibroblasts and myocytes. Springer

Carrick, D., Haig, C., Rauhalammi, S., Ahmed, N., Mordi, I., McEntegart, M., Petrie, M., Eteiba, H., Hood, S., Watkins, S., Lindsay, M., Marous, A., Radjenovic, A., Ford, I., Tzemos, N., Oldroyd, K., Berry, C. (2015) Pathophysiology of myocardial remodeling in survivors of ST-elevation myocardial infarction revealed by native T1 mapping: inflammation, remote myocardium and prognostic significance. Journal of Cardiovascular Magnetic Resonance, 17, (doi: 10.1186/1532-429X-17-S1-Q52)

Paul, L., Brewster, S., Wyke, S., Gill, J. M.R., Alexander, G., Dybus, A., Rafferty, D. (2015) Physical activity profiles and sedentary behaviour in people following stroke: a cross-sectional study. Disability and Rehabilitation, (doi: 10.3109/09638288.2015.1041615)

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Carrick, D., Haig, C., Rauhalammi, S. M., Ahmed, N., Mordi, I., McEntegart, M., Petrie, M., Eteiba, H., Hood, S., Watkins, S., Lindsay, M., Marous, A., Radjenovic, A., Ford, I., Tzemos, N., Oldroyd, K. G., Berry, C. (2015) Prognostic significance of infarct core pathology in ST-elevation myocardial infarction survivors revealed by non-contrast T1 mapping cardiac magnetic resonance. Journal of Cardiovascular Magnetic Resonance, 17, (doi: 10.1186/1532-429X-17-S1-O26)

Carrick, D., Haig, C., Rauhalammi, S., Ahmed, N., Mordi, I., McEntegart, M., Petrie, M., Eteiba, H., Hood, S., Watkins, S., Lindsay, M., Marous, A., Radjenovic, A., Ford, I., Tzemos, N., Oldroyd, K., Berry, C. (2015) Prognostic significance of infarct core pathology in ST-elevation myocardial infarction survivors revealed by quantitative T2-weighted cardiac magnetic resonance. Journal of Cardiovascular Magnetic Resonance, 17, (doi: 10.1186/1532-429X-17-S1-O54)

Carrick, D., Haig, C., Rauhalammi, S., Ahmed, N., Mordi, I., McEntegart, M., Petrie, M., Eteiba, H., Hood, S., Watkins, S., Lindsay, M., Marous, A., Radjenovic, A., Ford, I., Tzemos, N., Oldroyd, K., Berry, C. (2015) Prognostic significance of quantitative measures of myocardial infarct pathology using native T1 mapping, in survivors of ST-elevation myocardial infarction. Journal of Cardiovascular Magnetic Resonance, 17, pp. O53. (doi: 10.1186/1532-429X-17-S1-O53)

Abdul-Rahim, A. H., Perez, A.-C., Fulton, R. L., Jhund, P. S., Latini, R., Tognoni, G., Wikstrand, J., Kjekshus, J., Lip, G. Y.H., Maggioni, A. P., Tavazzi, L., Lees, K. R., McMurray, J. J.V. (2015) Response to Letter Regarding Article, “Risk of Stroke in Chronic Heart Failure Patients Without Atrial Fibrillation: Analysis of the Controlled Rosuvastatin in Multinational Trial Heart Failure (CORONA) and the Gruppo Italiano per lo Studio della Sopravvivenza nell’Insufficienza Cardiaca-Heart Failure (GISSI-HF) Trials.” Circulation, 132, (doi: 10.1161/CIRCULATIONAHA.115.018395)

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Lewsey, J., Ebueku, O., Jhund, P. S., Gillies, M., Chalmers, J. W.T., Redpath, A., Briggs, A., Walters, M., Langhorne, P., Capewell, S., McMurray, J. J.V., MacIntyre, K. (2015) Temporal trends and risk factors for readmission for infections, gastrointestinal and immobility complications after an incident hospitalisation for stroke in Scotland between 1997 and 2005. BMC Neurology, 15, (doi: 10.1186/s12883-014-0257-1)

Sattar, N., Welsh, P., Preiss, D. (2015) The insulin resistance syndrome. John Wiley & Sons, Ltd

Badar, A. A., Brunton, A. P.T., Mahmood, A. H., Dobbin, S., Pozzi, A., McMinn, J. F., Sinclair, A. J.E., Gardner, R. S., Petrie, M. C., Curry, P. A., Al-Attar, N. H.K., Pettit, S. J. (2015) The management of patients with aortic regurgitation and severe left ventricular dysfunction: a systematic review. Expert Review of Cardiovascular Therapy, 13, pp. 915-922. (doi: 10.1586/14779072.2015.1067139)

Brown, C. E., McCarthy, N. S., Hughes, A. D.,, Sever, P., Stalmach, A., Mullen, W., Dominiczak, A. F., Sattar, N., Mischak, H., Thom, S., Mayet, J., Stanton, A. V., Delles, C. (2015) Urinary proteomic biomarkers to predict cardiovascular events. Proteomics Clinical Applications, 9, pp. 610-617. (doi: 10.1002/prca.201400195)

PGR Students

Kai Wang

  • Postgraduate Research Student
  • Research title: Metabolic drivers of hypertension: focus on the microcirculation

The Glasgow Biomarker Research Unit (GlasBRU) is a facility that conducts blood and urine tests for research purposes. This includes conducting tests that are often routinely conducted as part of clinical care, as well as more experimental blood tests. We then use that information to change our understanding of the causes and consequences of cardiometabolic disease, and the way we use blood tests in real clinical practice. 

How do we conduct research? 

We have large biobanks of blood samples from different populations and studies that we use, or we use existing data from studies that are available to healthcare researchers such as UK Biobank, SAIL, and NHS Safehaven data. For example, 

  • We conduct blood tests in ongoing clinical trials to better understand the consequences of interventions like weight loss or new pharmacological treatments for heart failure. 
  • We conduct blood tests in population-based studies (observational studies) to better understand who develops cardiometabolic diseases and why, or what the biological consequences of health and disease are. 
  • We use information from blood tests to understand who is at risk of disease, and then use that information to better understand which patients might be screened for disease, allowing early intervention or prevention in clinical practice. 

Our collaborators and funders include researchers from across the world, industrial biomarker companies, industrial pharmacological companies, as well as charitable and UKRI funders. 

Impact 

Our world-class research has had an impact in a wide range of conditions and studies including: 

  • Weight Loss in The Diabetes Remission Clinical Trial (DiRECT) 
  • Heart Failure treatments (such as the DAPA-HF trial) 
  • Cardiovascular risk screening studies (in studies such as UK Biobank and Generation Scotland Family Study)