Ischaemic Heart Disease
Ischaemic heart disease (IHD) is a leading global cause of premature ill health and death. Our teams lead research and innovation to advance the science underpinning novel diagnostics and therapy for people with IHD.
Staff
Publications
2024
Rankin, S., Fountain, C., Gemmell, A. J., Quinn, D., Henderson, A., McClure, J., Small, S., Venugopal, B., McKay, P., Slomka, P. J., Colville, D., Petrie, M. C., Meléndez, G. C., Lang, N. N. (2024) Arterial effects of anthracycline: structural & inflammatory assessments in non-human primates and lymphoma patients. Clinical Science, (doi: 10.1042/CS20241529)
Wang, X., Vardeny, O., Claggett, B., Vaduganathan, M., Hegde, S. M., Skali, H., Pabon, M. A., Foà, A., Chatur, S., Kosztin, A., O'Meara, E., Rouleau, J., Redfield, M., Lam, C. S.P., Zile, M., Packer, M., Shah, A. M., Cikes, M., Gori, M., Merkely, B., Pfeffer, M. A., McMurray, J. J.V., Solomon, S. D. (2024) Effect of sacubitril/valsartan in heart failure with preserved ejection fraction across the age spectrum in PARAGON‐HF. European Journal of Heart Failure, (doi: 10.1002/ejhf.3535)
Carberry, J. et al. (2024) Empagliflozin to prevent worsening of left ventricular volumes and systolic function after myocardial infarction (EMPRESS-MI) European Journal of Heart Failure, (doi: 10.1002/ejhf.3560)
Leong, D. P., Joseph, P. G., Dokainish, H., Störk, S., McMurray, J. V.V., Mielniczuk, L. M., Sharma, S. K., Orlandini, A., Karaye, K. M., Bayes‐Genis, A., McCready, T., Grinvalds, A., Balasubramanian, K., Branch, K. R., Kragholm, K., Yusuf, S. (2024) The risk of death according to left ventricular ejection fraction and right ventricular dilatation in 17 321 adults with heart failure from 40 high-, middle- and low-income countries – A Global Congestive Heart Failure (G-CHF) study. European Journal of Heart Failure, (doi: 10.1002/ejhf.3550)
Bonaca, M. P. et al. (2024) Cardiovascular safety in oncology clinical trials: JACC: CardioOncology Primer. JACC: CardioOncology, (doi: 10.1016/j.jaccao.2024.09.014)
Monzo, L., Bresso, E., Dickstein, K., Pitt, B., Cleland, J. G.F., Anker, S. D., Lam, C. S.P., Mehra, M. R., van Veldhuisen, D. J., Greenberg, B., Zannad, F., Girerd, N. (2024) Machine learning approach to identify phenotypes in patients with ischemic heart failure with reduced ejection fraction. European Journal of Heart Failure, (doi: 10.1002/ejhf.3547)
Nakada, S., Welsh, P., Celis-Morales, C., Pell, J. P., Ho, F. K. (2024) Predictive values of depression and anxiety disorder over the PREVENT predictors: development of prediction models for 10-year risk of cardiovascular disease. Canadian Medical Association Journal,
De Biase, N., Del Punta, L., L'Hoyes, W., Pellicori, P., Cleland, J. G.F., Masini, G., Gargani, L., Moura-Ferreira, S., Hoedemakers, S., Di Fiore, V., Herbots, L., Stassen, J., Mengozzi, A., Armenia, S., Taddei, S., Masi, S., Verwerft, J., Pugliese, N. R. (2024) Associations of iron deficiency with cardiac function, congestion, exercise capacity and prognosis in heart failure. European Journal of Heart Failure, (doi: 10.1002/ejhf.3534)
Ang, D. T.Y., Carberry, J., Ford, T. J., Kamdar, A., Sykes, R., Sidik, N. P., Carrick, D., McCartney, P. J., Collison, D., Robertson, K., Shaukat, A., Rocchiccioli, J. P., McGeoch, R., Watkins, S., Hood, S., McEntegart, M., Lindsay, M., Eteiba, H., Oldroyd, K. G., Good, R., McConnachie, A., Berry, C. (2024) Coronary microvascular function and atherosclerotic plaque burden in ischaemia and no obstructive coronary arteries: a secondary analysis of the CorMicA trial. Heart, (doi: 10.1136/heartjnl-2024-324677)
Ho, F. K., Dale, C., Mizani, M. A., Bolton, T., Pearson, E. R., Valabhji, J., Delles, C., Welsh, P., Nakada, S., Mackay, D., Pell, J. P., Tomlinson, C., Petersen, S., Bray, B., Ashworth, M., Rahimi, K., Mamas, M., Halcox, J., Sudlow, C., Sofat, R., Sattar, N., CVD-COVID-UK/COVID-IMPACT Consortium, (2024) Routine measurement of cardiometabolic disease risk factors in primary care in England before, during and after the COVID-19 pandemic: a population-based cohort study. PLoS Medicine, 21, (doi: 10.1371/journal.pmed.1004485)
Docherty, K. F., Buendia Lopez, R., Folkvaljon, F., de Boer, R. A., Chen, J., Hammarstedt, A., Kitzman, D. W., Kosiborod, M. N., Langkilde, A. M., Reicher, B., Senni, M., Wilderäng, U., Verma, S., Cowie, M. R., Solomon, S. D., McMurray, J. J.V. (2024) Wearable accelerometer-derived measures of physical activity in heart failure: insights from the DETERMINE trials. Journal of Cardiac Failure, (doi: 10.1016/j.cardfail.2024.10.439)
Badve, S. V., Bilal, A., Lee, M. M. Y., Sattar, N., Gerstein, H. C., Ruff, C. T., McMurray, J. J. V., Rossing, P., Bakris, G., Mahaffey, K. W., Mann, J. F. E., Colhoun, H. M., Tuttle, K. R., Pratley, R. E., Perkovic, V. (2024) Effects of GLP-1 receptor agonists on kidney and cardiovascular disease outcomes: a meta-analysis of randomised controlled trials. Lancet Diabetes and Endocrinology, (doi: 10.1016/S2213-8587(24)00271-7)
Gupta, S. D., Butt, J. H., McMurray, E. G.M., Talebi, A., Matsumoto, S., Rizkala, A. R., Henderson, A. D., Desai, A. S., Lefkowitz, M., Packer, M., Rouleau, J. L., Solomon, S. D., Swedberg, K., Zile, M. R., Jhund, P. S., McMurray, J. J.V. (2024) Effects of sacubitril/valsartan according to background beta-blocker therapy in patients with heart failure and reduced ejection fraction: Insights from PARADIGM-HF. European Journal of Heart Failure, (doi: 10.1002/ejhf.3515)
Seckin, M., Petrie, M. C., Stewart, S., Johnston, B. M. (2024) A descriptive qualitative study of breathlessness and its management of Turkish individuals with self-reported heart failure. BMJ Open, 14, (doi: 10.1136/ bmjopen-2024-088335)
Ho, F. K., Mark, P. B., Lees, J. S., Pell, J. P., Strawbridge, R. J., Kimenai, D. M., Mills, N. L., Woodward, M., McMurray, J. J.V., Sattar, N., Welsh, P. (2024) A proteomics-based approach for prediction of different cardiovascular diseases and dementia. Circulation, (doi: 10.1161/CIRCULATIONAHA.124.070454)
Osmanska, J., Petrie, M. C., Docherty, K. F., Lee, M. M.Y., McMurray, J. J.V., Campbell, R. (2024) Subcutaneous furosemide in heart failure: a systematic review. European Heart Journal: Cardiovascular Pharmacotherapy, (doi: 10.1093/ehjcvp/pvae083)
Averbuch, T., Lee, S. F., Zagorski, B., Pandey, A., Petrie, M. C., Biering‐Sorensen, T., Xie, F., Van Spall, H. G.C. (2024) Long‐term clinical outcomes and healthcare resource utilization in male and female patients following hospitalization for heart failure. European Journal of Heart Failure, (doi: 10.1002/ejhf.3499)
Zervou, S., McAndrew, D. J., Lake, H. A., Kuznecova, E., Preece, C., Davies, B., Neubauer, S., Lygate, C. A. (2024) Cardiac function and energetics in mice with combined genetic augmentation of creatine and creatine kinase activity. Journal of Molecular and Cellular Cardiology, 196, pp. 105-114. (doi: 10.1016/j.yjmcc.2024.09.007)
Fletcher, R. A. et al. (2024) Contemporary epidemiology of hospitalised heart failure with reduced versus preserved ejection fraction in England: a retrospective, cohort study of whole-population electronic health records. Lancet Public Health, 9, pp. e871-e885. (doi: 10.1016/S2468-2667(24)00215-9)
Butt, J. H., Shen, L., Inzucchi, S. E., Docherty, K. F., Jhund, P. S., Martinez, F. A., Sabatine, M. S., Vaduganathan, M., Solomon, S. D., McMurray, J. J.V. (2024) Dapagliflozin in heart failure, type 2 diabetes, and neuropathy. JACC: Heart Failure, 12, pp. 1946-1948. (doi: 10.1016/j.jchf.2024.07.017)
Fullerton, J. L., Hay, J., Bryant-Craig, C., Atkinson, J., Smith, D. H., Stewart, W. (2024) Pediatric traumatic brain injury and microvascular blood-brain barrier pathology. JAMA Network Open, 7, (doi: 10.1001/jamanetworkopen.2024.46767)
Main, A., Mary, S., Sin, Y. Y., Wright, T. A., Ling, J., Blair, C. M., Smith, G. L., Fuller, W., Baillie, G. S. (2024) SUMOylation of cardiac myosin binding protein-C reduces its phosphorylation and results in impaired relaxation following treatment with isoprenaline. International Journal of Biochemistry and Cell Biology, 176, (doi: 10.1016/j.biocel.2024.106668)
Rochmawati, I. D., Deo, S., Lees, J. S., Mark, P. B., Sattar, N., Celis-Morales, C., Pell, J. P., Welsh, P., Ho, F. K. (2024) Adding traditional and emerging biomarkers for risk assessment in secondary prevention: a prospective cohort study of 20,656 patients with cardiovascular disease. European Journal of Preventive Cardiology, (doi: 10.1093/eurjpc/zwae352)
Xiong, X., Lui, D. T.W., Ju, C., Zhou, Z., Xu, C., Welsh, P., Sattar, N., Celis-Morales, C., Pell, J. P., Wong, I. C.K., Wong, C. K.H., Ho, F. (2024) Associations of serum lipid traits with fracture and osteoporosis: a prospective cohort study from the UK Biobank. Journal of Cachexia, Sarcopenia and Muscle, (doi: 10.1002/jcsm.13611)
Dieden, A., Girerd, N., Ottosson, F., Molvin, J., Pareek, M., Melander, O., Bachus, E., Råstam, L., Lindblad, U., Daka, B., Leósdóttir, M., Nilsson, P. M., Olsen, M. H., Clark, A. L., Cleland, J. G.F., Delles, C., González, A., Lamiral, Z., Duarte, K., Rossignol, P., Zannad, F., Gudmundsson, P., Jujić, A., Magnusson, M. (2024) Proteomic biomarkers and pathway analysis for progression to heart failure in three epidemiological representative cohorts. European Journal of Heart Failure, (doi: 10.1002/ejhf.3502)
Foley, P.W., Kalra, P.R., Cleland, J.G.F., Petrie, M.C., Kalra, P.A., Squire, I., Campbell, P., Chapman, C., Donnelly, P., Graham, F., Hannah, A., Lang, N.N., Matthews, I., Leslie, S.J., Pellicori, P., Piper, S., Ray, R., Savage, H.O., Spencer, C., Walsh, J., Wong, Y., Ford, I. (2024) Effect of correcting iron deficiency on the risk of serious infection in heart failure insights from the IRONMAN trial. European Journal of Heart Failure, (doi: 10.1002/ejhf.3504)
Lu, H., Claggett, B. L., Packer, M., Pfeffer, M. A., Swedberg, K., Rouleau, J., Zile, M. R., Lefkowitz, M., Desai, A. S., Jhund, P. S., McMurray, J. J.V., Solomon, S. D., Vaduganathan, M. (2024) Visit‐to‐visit changes in heart rate in heart failure: A pooled participant‐level analysis of the PARADIGM‐HF and PARAGON‐HF trials. European Journal of Heart Failure, (doi: 10.1002/ejhf.3487)
Alharbi, A., Nurfianti, A., Mullen, R. F., McClure, J. D., Miller, W. H. (2024) The effectiveness of simulation-based learning (SBL) on students' knowledge and skills in nursing programs: a systematic review. BMC Medical Education, 24, (doi: 10.1186/s12909-024-06080-z)
Varga, C. R., Cleland, J. G.F., Abraham, W. T., Lip, G. Y.H., Leyva, F., Hatamizadeh, P. (2024) Implantable cardioverter defibrillator and resynchronization therapy in patients with overt chronic kidney disease. Journal of the American College of Cardiology, 84, pp. 1342-1362. (doi: 10.1016/j.jacc.2024.05.081)
Ho, F., Allan, M., Shao, H., Man, K. K.C., Jani, B. D., Lyall, D., Hastie, C., Fleming, M., Mackay, D., Cleland, J. G.F., Delles, C., Dundas, R., Lewsey, J., Ip, P., Wong, I., Welsh, P., Pearce, A., Wright, C. M., Minnis, H., Katikireddi, V., Pell, J. P. (2024) Maternal and pregnancy factors contributing to the association between area deprivation and infant mortality in England: a retrospective cohort study. Lancet Regional Health - Europe, (doi: 10.1016/j.lanepe.2024.101075)
Lee, M., Petrie, M. C., Cleland, J. G.F., Donnelly, P., Francis, M., Hannah, A., Japp, A. G., Labinjoh, C., Lang, N. N., Mainsty, C., Petrie, C. J., Piper, S. E., Williams, S. G., Ford, I., Kalra, P. R., IRONMAN Trial Investigators, (2024) Administration of ferric derisomaltose for iron deficiency and heart failure during hospital admission or at the clinic – insights from the IRONMAN trial. European Journal of Heart Failure, 26, pp. 2293-2295. (doi: 10.1002/ejhf.3394)
Liu, Q., Celis-Morales, C., Lees, J. S., Sattar, N., Ho, F., Pell, J. P., Mark, P. B., Welsh, P. (2024) Change in physical activity and its association with decline in kidney function: A UK Biobank-based cohort study. Journal of Cachexia, Sarcopenia and Muscle, 15, pp. 2046-2055. (doi: 10.1002/jcsm.13551)
Docherty, K. F., Lopez, R. B., Folkvaljon, F., de Boer, R. A., Cowie, M. R., Hammarstedt, A., Kitzman, D. W., Kosiborod, M. N., Langkilde, A. M., Reicher, B., Senni, M., Shah, S. J., Verma, S., Solomon, S. D., McMurray, J. J.V. (2024) Effect of dapagliflozin on accelerometer-based measures of physical activity in patients with heart failure: an analysis of the DETERMINE trials. Circulation: Heart Failure, 17, (doi: 10.1161/CIRCHEARTFAILURE.124.012349)
Cleland, J. G.F. (2024) Home-time is good, but feeling well is better: patient-journey and quality-home-time as endpoints in heart failure trials and registries. Circulation: Heart Failure, 17, (doi: 10.1161/CIRCHEARTFAILURE.124.012263)
Abdin, A., Jhund, P. S. (2024) Implementation of guideline‐directed medical therapy for heart failure: Progress achieved, work ahead! European Journal of Heart Failure, 26, pp. 2258-2260. (doi: 10.1002/ejhf.3438)
Sliwa, K., Rakisheva, A., Viljoen, C., Pfeffer, T., Simpson, M., Jackson, A. M., Petrie, M. C., van der Meer, P., Al Farhan, H., Jovanova, S., Mbakwem, A., Sinagra, G., Van Craenenbroeck, E., Hoevelmann, J., Johnson, M. R., Mindham, R., Chioncel, O., Kahl, K. G., Rosano, G., Tschöpe, C., Mebazaa, A., Seferovic, P., Bauersachs, J. (2024) Living with peripartum cardiomyopathy: A statement from the Heart Failure Association and the Association of Cardiovascular Nursing and Allied Professions of the European Society of Cardiology. European Journal of Heart Failure, 26, pp. 2143-2154. (doi: 10.1002/ejhf.3377)
Pellicori, P., Cuthbert, J. J., Clark, A. L., Cleland, J. G.F. (2024) Managing water and salt balance in heart failure: Is there anything else to consider other than diet and diuretics? European Journal of Heart Failure, 26, pp. 2140-2142. (doi: 10.1002/ejhf.3374)
Keene, D. et al. (2024) Predictors of the efficacy of His bundle pacing in patients with a prolonged PR interval: A stratified analysis of the HOPE‐HF randomized controlled trial. European Journal of Heart Failure, 26, pp. 2261-2268. (doi: 10.1002/ejhf.3367)
Chatur, S., Beldhuis, I. E., Claggett, B. L., McCausland, F. R., Neuen, B. L., Desai, A. S., Rouleau, J. L., Zile, M. R., Packer, M., Pfeffer, M. A., Lefkowitz, M. P., McMurray, J. J.V., Solomon, S. D., Vaduganathan, M. (2024) Sacubitril/valsartan in patients with heart failure and deterioration in eGFR to <30 mL/min/1.73 m2. JACC: Heart Failure, 12, pp. 1692-1703. (doi: 10.1016/j.jchf.2024.03.014)
Yu, Y.-L. et al. (2024) Urinary proteomic signature of mineralocorticoid receptor antagonism by spironolactone: evidence from the HOMAGE trial. Heart, 110, pp. 1180-1187. (doi: 10.1136/heartjnl-2023-323796)
Cheng, L., Hammersley, D., Ragavan, A., Javed, S., Mukhopadhyay, S., Gregson, J., Han, J., Khalique, Z., Lota, A., Pantazis, A., Baksi, A. J., Carr‐White, G., de Marvao, A., Ware, J., Tayal, U., Pennell, D. J., Cleland, J. G.F., Prasad, S. K., Halliday, B. P. (2024) Long‐term follow‐up of the TRED ‐ HF trial: Implications for therapy in patients with dilated cardiomyopathy and heart failure remission. European Journal of Heart Failure, (doi: 10.1002/ejhf.3475)
Wang, X., Pabon, M. A., Cikes, M., Jering, K., Mullens, W., Kober, L., Jhund, P. S., Kovacs, A., Merkely, B., Zhou, Y., McMurray, J. J.V., Shah, A. M., Hegde, S. M., Claggett, B., Pfeffer, M. A., Solomon, S. D. (2024) Sex differences in cardiac structure and function following acute myocardial infarction: Insights from the PARADISE‐MI echocardiographic substudy. European Journal of Heart Failure, (doi: 10.1002/ejhf.3472)
Jhund, P. S., Talebi, A., Henderson, A. D., Claggett, B. L., Vaduganathan, M., Desai, A. S., Lam, C. S.P., Pitt, B., Senni, M., Shah, S. J., Voors, A. A., Zannad, F., Solomon, S. D., McMurray, J. J.V. (2024) Mineralocorticoid receptor antagonists in heart failure: an individual patient level meta-analysis. Lancet, 404, pp. 1119-1131. (doi: 10.1016/S0140-6736(24)01733-1)
Anderson, J. J., Deo, S. V., Welsh, P., Mackay, D. F., Ho, F. K., Ferguson, L. D., Celis-Morales, C., Gill, J.R., Pell, J. P., Sattar, N. (2024) In which common chronic conditions can (or cannot) obesity and lifestyle factors explain higher concentrations of C-reactive protein? Diabetes, Obesity and Metabolism, (doi: 10.1111/dom.15949)
Pabon, M. A., Vaduganathan, M., Claggett, B. L., Chatur, S., Siqueira, S., Marti‐Castellote, P., de Boer, R. A., Hernandez, A. F., Inzucchi, S. E., Kosiborod, M. N., Lam, C. S.P., Martinez, F., Shah, S. J., Desai, A. S., Jhund, P. S., McMurray, J. J.V., Solomon, S. D., Vardeny, O. (2024) In‐hospital course of patients with heart failure with improved ejection fraction in the DELIVER trial. European Journal of Heart Failure, (doi: 10.1002/ejhf.3410)
Valentova, M., Vatic, M., Garfias-Veitl, T., Sandek, A., Bekfani, T., Jankowska, E. A., Cleland, J. G.F., Clark, A. L., Lainscak, M., Ahmed, A., Jauert, N., Hasenfuss, G., Anker, S. D., Doehner, W., von Haehling, S. (2024) Diabetes mellitus is associated with low exercise capacity and impaired peripheral vasodilation in patients with heart failure – a propensity score-matched stud. Diabetes Research and Clinical Practice,
Greene, S. J. et al. (2024) Cardiovascular and renal treatment in heart failure patients with hyperkalemia or high risk of hyperkalemia: rationale and design of the CARE-HK in HF registry. Journal of Cardiac Failure, (doi: 10.1016/j.cardfail.2024.08.048)
Cuthbert, J. J., Cleland, J. G. F., Pellicori, P., Clark, A. L. (2024) Natriuresis guided diuresis in patients admitted to hospital with heart failure – barking up the wrong tree? Journal of Cardiac Failure,
Lu, H., Claggett, B. L., Packer, M., Pfeffer, M. A., Lam, C. S.P., Zile, M. R., Desai, A. S., Jhund, P., Lefkowitz, M., McMurray, J. J.V., Solomon, S. D., Vaduganathan, M. (2024) Sacubitril/valsartan reduces incident anaemia and iron therapy utilization in heart failure: The PARAGON‐HF trial. European Journal of Heart Failure, (doi: 10.1002/ejhf.3414)
Morrow, A. et al. (2024) Zibotentan in microvascular angina: a randomized, placebo-controlled, crossover trial. Circulation, (doi: 10.1161/CIRCULATIONAHA.124.069901)
Al-Abdullah, L., Ahern, A., Welsh, P., Logue, J. (2024) A predictive model for medium-term weight loss response in people with type 2 diabetes engaging in behavioural weight management interventions. Diabetes, Obesity and Metabolism, 26, pp. 3653-3662. (doi: 10.1111/dom.15706)
Mc Causland, F. R., McGrath, M. M., Claggett, B. L., Barkoudah, E., East, C., Fernandez, A., Jering, K. S., Lewis, E. F., McMurray, J. J.V., Mody, F. V., Solomon, S. D., Tokmakova, M., van der Meer, P., Zhou, Y., Pfeffer, M. A. (2024) Acute changes in kidney function and outcomes following an acute myocardial infarction: Insights from PARADISE-MI. European Journal of Heart Failure, 26, pp. 1984-1992. (doi: 10.1002/ejhf.3386)
van der Meer, P., van Essen, B., Viljoen, C., Böhm, M., Jackson, A., Hilfiker-Kleiner, D., Hoevelmann, J., Mebazaa, A., Farhan, H. A., Goland, S., Ouwerkerk, W., Petrie, M. C., Seferović, P. M., Tromp, J., Sliwa, K., Bauersachs, J. (2024) Bromocriptine treatment and outcomes in peripartum cardiomyopathy: the EORP PPCM registry. European Heart Journal, (doi: 10.1093/eurheartj/ehae559)
Butt, J., Jhund, P. S., Docherty, K. F., Claggett, B. L., Vaduganathan, M., Bachus, E., Hernandez, A. F., Lam, C. S.P., Inzucchi, S. E., Martinez, F. A., de Boer, R. A., Kosiborod, M. N., Desai, A. S., Køber, L., Ponikowski, P., Sabatine, M. S., Solomon, S. D., McMurray, J. J.V. (2024) Dapagliflozin and timing of prior heart failure hospitalization a patient-level meta-analysis of DAPA-HF and DELIVER. JACC: Heart Failure, 12, pp. 1586-1599. (doi: 10.1016/j.jchf.2024.01.018)
Seferović, P. M., Paulus, W. J., Rosano, G., Polovina, M., Petrie, M. C., Jhund, P. S., Tschöpe, C., Sattar, N., Piepoli, M., Papp, Z., Standl, E., Mamas, M. A., Valensi, P., Linhart, A., Lalić, N., Ceriello, A., Döhner, W., Ristić, A., Milinković, I., Seferović, J., Cosentino, F., Metra, M., Coats, A. J.S. (2024) Diabetic myocardial disorder. A clinical consensus statement of the Heart Failure Association of the ESC and the ESC Working Group on Myocardial & Pericardial Diseases. European Journal of Heart Failure, 26, pp. 1893-1903. (doi: 10.1002/ejhf.3347)
Ryan, M., Taylor, D., Dodd, M., Spertus, J. A., Kosiborod, M. N., Shaukat, A., Docherty, K. F., Clayton, T., Perera, D., Petrie, M. C., REVIVED-BCIS2 Investigators, (2024) Effect of PCI on health status in ischemic left ventricular dysfunction: insights from REVIVED-BCIS2. JACC: Heart Failure, 12, pp. 1553-1562. (doi: 10.1016/j.jchf.2024.03.010)
Abdin, A., Kondo, T., Böhm, M., Jhund, P. S., Claggett, B. L., Vaduganathan, M., Hernandez, A. F., Lam, C. S.P., Inzucchi, S. E., Martinez, F. A., de Boer, R. A., Desai, A. S., Køber, L., Sabatine, M. S., Petersson, M., Bachus, E., Solomon, S. D., McMurray, J. (2024) Effects of dapagliflozin according to QRS duration across the spectrum of left ventricular ejection fraction: an analysis of DAPA-HF and DELIVER. European Journal of Heart Failure, 26, pp. 1952-1963. (doi: 10.1002/ejhf.3350)
Tabish, T. A., Hussain, M. Z., Zhu, Y., Xu, J., Huang, W. E., Diotallevi, M., Narayan, R. J., Crabtree, M. J., Khademhosseini, A., Winyard, P. G., Lygate, C. (2024) Synthesis and characterization of amine-functionalized graphene as a nitric oxide-generating coating for vascular stents. Applied Physics Reviews, 11, (doi: 10.1063/5.0192379)
Butt, J. H., McMurray, J. J.V., Claggett, B. L., Jhund, P. S., Neuen, B. L., McCausland, F., Desai, A., Lam, C. S.P., Pitt, B., Pfeffer, M. A., Packer, M., Beldhuis, I., Voors, A. A., Zannad, F., Heerspink, H. J.L., Solomon, S. D., Vaduganathan, M. (2024) Therapeutic effects of heart failure medical therapies on standardized kidney outcomes: Comprehensive individual participant-level analysis of 6 randomized clinical trials. Circulation, (doi: 10.1161/circulationaha.124.071110)
Matsumoto, S., Henderson, A. D., Shen, L., Kondo, T., Yang, M., Campbell, R. T., Anand, I. S., de Boer, R. A., Desai, A. S., Lam, C. S.P., Maggioni, A. P., Martinez, F. A., Packer, M., Redfield, M. M., Rouleau, J. L., Van Veldhuisen, D. J., Vaduganathan, M., Zannad, F., Zile, M. R., Jhund, P. S., Solomon, S. D., McMurray, J. J.V. (2024) Beta‐blocker use and outcomes in patients with heart failure and mildly reduced and preserved ejection fraction. European Journal of Heart Failure, (doi: 10.1002/ejhf.3383)
Ponikowski, P. et al. (2024) Hospitalization of symptomatic patients with heart failure and moderate to severe functional mitral regurgitation treated with MitraClip: insights from RESHAPE-HF2. JACC: Heart Failure, (doi: 10.1016/j.jacc.2024.08.027)
McNeilly, S. et al. (2024) Collagen IV deficiency causes hypertrophic remodeling and endothelium-dependent hyperpolarization in small vessel disease with intracerebral hemorrhage. EBioMedicine, 107, (doi: 10.1016/j.ebiom.2024.105315)
Giannitsis, E., Frey, N., Jhund, P. S. (2024) Improving the rate of heart failure with improved ejection fraction. European Journal of Heart Failure, (doi: 10.1002/ejhf.3427)
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2023
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2022
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2021
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Burton, R. F., Burton, F. L. (2021) When is sitting height a better measure of adult body size than total height, and why? The contrasting examples of body mass, waist circumference and lung volume. American Journal of Human Biology, 33, (doi: 10.1002/ajhb.23433)
Mortensen, P., Gao, H., Smith, G., Simitev, R. D. (2021) Addendum: Action potential propagation and block in a model of atrial tissue with myocyte-fibroblast coupling. Mathematical Medicine and Biology, 38, pp. 292-298. (doi: 10.1093/imammb/dqab005)
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2020
Brown, R., Welsh, P., Logue, J. (2020) Systematic review of clinical guidelines for lipid-lowering in the secondary prevention of cardiovascular disease events. Open Heart, 7, (doi: 10.1136/openhrt-2020-001396)
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2019
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2018
Lemme, M., Ulmer, B. M., Lemoine, M. D., Zech, A. T.L., Flenner, F., Ravens, U., Reichenspurner, H., Rol-Garcia, M., Smith, G., Hansen, A., Christ, T., Eschenhagen, T. (2018) Atrial-like engineered heart tissue: an in vitro model of the human atrium. Stem Cell Reports, 11, pp. 1378-1390. (doi: 10.1016/j.stemcr.2018.10.008)
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Pellicori, P., Urbinati, A., Zhang, J., Joseph, A. C., Costanzo, P., Lukaschuk, E., Capucci, A., Cleland, J. G.F., Clark, A. L. (2018) Clinical and prognostic relationships of pulmonary artery to aorta diameter ratio in patients with heart failure: a cardiac magnetic resonance imaging study. Clinical Cardiology, 41, pp. 20-27. (doi: 10.1002/clc.22840)
Patel, N., Hellmuth, C., Uhl, O., Godfrey, K., Briley, A., Welsh, P., Pasupathy, D., Seed, P., Koletzko, B., Poston, L. (2018) Cord metabolic profiles In obese pregnant women; insights into offspring growth and body composition. Journal of Clinical Endocrinology and Metabolism, 103, pp. 346-355. (doi: 10.1210/jc.2017-00876)
McMurray, J. J.V., Ponikowski, P., Bolli, G. B., Lukashevich, V., Kozlovski, P., Kothny, W., Lewsey, J. D., Krum, H. (2018) Effects of vildagliptin on ventricular function in patients with type 2 diabetes mellitus and heart failure: a randomized placebo-controlled trial. JACC: Heart Failure, 6, pp. 8-17. (doi: 10.1016/j.jchf.2017.08.004)
Rørth, R., Fosbøl, E. L., Mogensen, U. M., Kragholm, K., Jhund, P. S., Petrie, M. C., Schou, M., Gislason, G. H., McMurray, J. J.V., Torp-Pedersen, C., Køber, L., Kristensen, S. L. (2018) Evidence based therapy and its association with workforce detachment following first hospitalization for heart failure. JACC: Heart Failure, 6, pp. 41-48. (doi: 10.1016/j.jchf.2017.09.019)
Beggs, S. A.S., Jhund, P. S., Jackson, C. E., McMurray, J. J.V., Gardner, R. S. (2018) Non-ischaemic cardiomyopathy, sudden death and implantable defibrillators: a review and meta-analysis. Heart, 104, pp. 144-150. (doi: 10.1136/heartjnl-2016-310850)
Maznyczka, A. M., McCartney, P., Berry, C. (2018) Reference invasive tests of microvascular injury in myocardial infarction. BMJ Open, 104, pp. 90-92. (doi: 10.1136/heartjnl-2017-311695)
Lee, M. M.Y. et al. (2018) Routine Non-invasive vs Invasive Management in Patients With Prior CABG With a NSTE-ACS: a Randomised Controlled Trial. (doi: 10.1136/heartjnl-2018-BCIS.9)
Souteyrand, G., Valladier, M., Amabile, N., Derimay, F., Harbaoui, B., Leddet, P., Barnay, P., Malcles, G., Mulliez, A., Berry, C., Eschalier, R., Combaret, N., Motreff, P. (2018) Diagnosis and management of spontaneously recanalized coronary thrombus guided by optical coherence tomography ― lessons from the French “Lotus Root” registry ― Circulation Journal, 82, pp. 783-790. (doi: 10.1253/circj.cj-17-0810)
Chuaiphichai, S., Rashbrook, V. S., Hale, A. B., Trelfa, L., Patel, J., McNeill, E., Lygate, C. A., Channon, K. M., Douglas, G. (2018) Endothelial cell tetrahydrobiopterin modulates sensitivity to ang (angiotensin) II–induced vascular remodeling, blood pressure, and abdominal aortic aneurysm. Hypertension, 72, pp. 128-138. (doi: 10.1161/HYPERTENSIONAHA.118.11144)
Lachaud, Q., MacQuaide, N., Burton, F., Smith, G. (2018) High-throughput study of rabbit ventricle action potential populations in MI model. Biophysical Journal, 114, pp. 625A. (doi: 10.1016/j.bpj.2017.11.3377)
Berry, C., Carberry, J., Mangion, K. (2018) How to mend a broken heart? JACC: Cardiovascular Imaging, 11, pp. 420-422. (doi: 10.1016/j.jcmg.2017.02.017)
McAllister, D. A., Read, S., Kerssens, J., Livingstone, S., McGurnaghan, S., Jhund, P., Petrie, J., Sattar, N., Fischbacher, C., Kristensen, S. L., McMurray, J., Colhoun, H. M., Wild, S. (2018) Incidence of hospitalisation for heart failure and case-fatality among 3.25 million people with and without diabetes. Circulation, 138, pp. 2774-2785. (doi: 10.1161/CIRCULATIONAHA.118.034986)
Rørth, R., Fosbøl, E. L., Kragholm, K., Mogensen, U. M., Jhund, P. S., Petrie, M. C., Torp-Pedersen, C., Gislason, G. H., McMurray, J. J.V., Køber, L., Kristensen, S. L. (2018) Initiation of domiciliary care and nursing home admission following first hospitalization for heart failure: a nationwide cohort study. Clinical Epidemiology, 10, pp. 917-930. (doi: 10.2147/CLEP.S164795)
Macdougall, I. C., White, C., Anker, S. D., Bhandari, S., Farrington, K., Kalra, P. A., McMurray, J. J.V., Murray, H., Steenkamp, R., Tomson, C. R.V., Wheeler, D. C., Winearls, C. G., Ford, I. (2018) Randomized trial comparing proactive, high-dose versus reactive, low-dose intravenous iron supplementation in hemodialysis (PIVOTAL): study design and baseline data. American Journal of Nephrology, 48, pp. 260-268. (doi: 10.1159/000493551)
Kraus, W. E., Yates, T., Tuomilehto, J., Sun, J.-L., Thomas, L., McMurray, J. J.V., Bethel, M. A., Holman, R. R. (2018) Relationship between baseline physical activity assessed by pedometer count and new-onset diabetes in the NAVIGATOR trial. BMJ Open Diabetes Research and Care, 6, (doi: 10.1136/bmjdrc-2018-000523)
Seferovic, J. P., Bentley-Lewis, R., Claggett, B., Diaz, R., Gerstein, H. C., Køber, L. V., Lawson, F. C., Lewis, E. F., Maggioni, A. P., McMurray, J. J.V., Probstfield, J. L., Riddle, M. C., Solomon, S. D., Tardif, J.-C., Pfeffer, M. A. (2018) Retinopathy, neuropathy, and subsequent cardiovascular events in patients with type 2 diabetes and acute coronary syndrome in the ELIXA: the importance of disease duration. Journal of Diabetes Research, 2018, (doi: 10.1155/2018/1631263)
Verma, S., McMurray, J. J.V. (2018) SGLT2 inhibitors and mechanisms of cardiovascular benefit: a state-of-the-art review. Diabetologia, 61, pp. 2108-2117. (doi: 10.1007/s00125-018-4670-7)
Layland, J., Tong, D., Lee, M., Berry, C. (2018) ST and T-Wave Abnormality as Footprint of Myocardial Oedema in Non–ST-Elevation Myocardial Infarction. (doi: 10.1016/j.hlc.2018.06.515)
Bouabdallaoui, N. et al. (2018) Society of Thoracic Surgeons risk score and EuroSCORE-2 appropriately assess 30-day postoperative mortality in the STICH trial and a contemporary cohort of patients with left ventricular dysfunction undergoing surgical revascularization. Circulation: Heart Failure, 11, (doi: 10.1161/circheartfailure.118.005531)
2017
Avtaar Singh, S. S., Das De, S., Spadaccio, C., Berry, C., Al-Attar, N. (2017) An overview of different methods of myocardial protection currently employed peri-transplantation. Vessel Plus, 1, pp. 213-229. (doi: 10.20517/2574-1209.2017.26)
Van't Veer, M., Pijls, N. H.J., Hennigan, B., Watkins, S., Ali, Z. A., De Bruyne, B., Zimmermann, F. M., van Nunen, L. X., Barbato, E., Berry, C., Oldroyd, K. G. (2017) Comparison of different diastolic resting indexes to iFR: are they all equal? Journal of the American College of Cardiology, 70, pp. 3088-3096. (doi: 10.1016/j.jacc.2017.10.066)
Ford, T. J., Berry, C., De Bruyne, B., Yong, A. C.S., Barlis, P., Fearon, W. F., Ng, M. K.C. (2017) Physiological predictors of acute coronary syndromes: emerging insights from the plaque to the vulnerable patient. JACC: Cardiovascular Interventions, 10, pp. 2539-2547. (doi: 10.1016/j.jcin.2017.08.059)
Berry, C., McClure, J. D., Oldroyd, K. G. (2017) Meta-analysis of death and myocardial infarction in the DEFINE-FLAIR and iFR-SWEDEHEART trials: a hypothesis generating note of caution. Circulation, 136, pp. 2389-2391. (doi: 10.1161/CIRCULATIONAHA.117.030430)
Lei, C. L., Wang, K., Clerx, M., Johnstone, R. H., Hortigon-Vinagre, M. P., Zamora, V., Allan, A., Smith, G. L., Gavaghan, D. J., Mirams, G. R., Polonchuk, L. (2017) Tailoring mathematical models to stem-cell derived cardiomyocyte lines can improve predictions of drug-induced changes to their electrophysiology. Frontiers in Physiology, 8, (doi: 10.3389/fphys.2017.00986)
Duncan, G., Firth, K., George, V., Hoang, M. D., Staniforth, A., Smith, G., Denning, C. (2017) Drug-mediated shortening of action potentials in LQTS2 human induced pluripotent stem cell-derived cardiomyocytes. Stem Cells and Development, 26, pp. 1695-1705. (doi: 10.1089/scd.2017.0172)
Celis-Morales, C. A., Petermann, F., Hui, L., Lyall, D. M., Iliodromiti, S., McLaren, J., Anderson, J., Welsh, P., Mackay, D. F., Pell, J. P., Sattar, N., Gill, J. M.R., Gray, S. R. (2017) Associations between diabetes and both cardiovascular disease and all-cause mortality are modified by grip strength: evidence from UK Biobank, a prospective population-based cohort study. Diabetes Care, 40, pp. 1710-1718. (doi: 10.2337/dc17-0921)
Kaye, D. M., Silvestry, F. E., Gustafsson, F., Cleland, J. G., van Veldhuisen, D. J., Ponikowski, P., Komtebedde, J., Nanayakkara, S., Burkhoff, D., Shah, S. J. (2017) Impact of atrial fibrillation on rest and exercise haemodynamics in heart failure with mid-range and preserved ejection fraction. European Journal of Heart Failure, 19, pp. 1690-1697. (doi: 10.1002/ejhf.930)
Hilfiker-Kleiner, D., Haghikia, A., Masuko, D., Nonhoff, J., Held, D., Libhaber, E., Petrie, M. C., Walker, N. L., Podewski, E., Berliner, D., Bauersachs, J., Sliwa, K. (2017) Outcome of subsequent pregnancies in patients with a history of peripartum cardiomyopathy. European Journal of Heart Failure, 19, pp. 1723-1728. (doi: 10.1002/ejhf.808)
Carberry, J., Carrick, D., Haig, C., Ahmed, N., Mordi, I., McEntegart, M., Petrie, M. C., Eteiba, H., Hood, S., Watkins, S., Lindsay, M., Davie, A., Mahrous, A., Ford, I., Sattar, N., Welsh, P., Radjenovic, A., Oldroyd, K. G., Berry, C. (2017) Persistence of infarct zone T2 hyperintensity at 6 months after acute ST-elevation myocardial infarction: incidence, pathophysiology and prognostic implications. Circulation: Cardiovascular Imaging, 10, (doi: 10.1161/CIRCIMAGING.117.006586)
Kristensen, S. L., Jhund, P. S., Lee, M. M.Y., Køber, L., Solomon, S. D., Granger, C. B., Yusuf, S., Pfeffer, M. A., Swedberg, K., McMurray, J. J.V. (2017) Prevalence of prediabetes and undiagnosed diabetes in patients with HFpEF and HFrEF and associated clinical outcomes. Cardiovascular Drugs and Therapy, 31, pp. 545-549. (doi: 10.1007/s10557-017-6754-x)
Senni, M., McMurray, J. J.V., Wachter, R., McIntyre, H. F., Anand, I. S., Duino, V., Sarkar, A., Shi, V., Charney, A. (2017) Impact of systolic blood pressure on the safety and tolerability of initiating and up-titrating sacubitril/valsartan in patients with heart failure and reduced ejection fraction: insights from the TITRATION study. European Journal of Heart Failure, 20, pp. 491-500. (doi: 10.1002/ejhf.1054)
Wang, G., Durussel, J., Shurlock, J., Mooses, M., Fuku, N., Bruinvels, G., Pedlar, C., Burden, R., Murray, A., Yee, B., Keenan, A., McClure, J. D., Sottas, P.-E., Pitsiladis, Y. P. (2017) Validation of whole-blood transcriptome signature during microdose recombinant human erythropoietin (rHuEpo) administration. BMC Genomics, 18, (doi: 10.1186/s12864-017-4191-7)
Vieira, M. C., White, S. L., Patel, N., Seed, P. T., Briley, A. L., Sandall, J., Welsh, P., Sattar, N., Nelson, S. M., Lawlor, D. A., Poston, L., Pasupathy, D. (2017) Prediction of uncomplicated pregnancies in obese women: a prospective multicentre study. BMC Medicine, 15, (doi: 10.1186/s12916-017-0956-8)
Sartini, C., Whincup, P. H., Wannamethee, S. G., Jefferis, B. J., Lennon, L., Lowe, G. D.O., Welsh, P., Sattar, N., Morris, R. W. (2017) Associations of time of day with cardiovascular disease risk factors measured in older men: results from the British Regional Heart Study. BMJ Open, 7, (doi: 10.1136/bmjopen-2017-018264)
Shen, L., Ramires, F., Martinez, F., Bodanese, L. C., Echeverría, L. E., Gómez, E. a., Abraham, W. t., Dickstein, K., Køber, L., Packer, M., Rouleau, J. L., Solomon, S. D., Swedberg, K., Zile, M. R., Jhund, P. S., Gimpelewicz, C. R., McMurray, J. J.V. (2017) Contemporary characteristics and outcomes in chagasic heart failure compared with other nonischemic and ischemic cardiomyopathy. Circulation: Heart Failure, 10, (doi: 10.1161/CIRCHEARTFAILURE.117.004361)
Holman, R. R., Coleman, R. L., Chan, J. C. N., Chiasson, J.-L., Feng, H., Ge, J., Gerstein, H. C., Gray, R., Huo, Y., Lang, Z., McMurray, J. J., Rydén, L., Schröder, S., Sun, Y., Theodorakis, M. J., Tendera, M., Tucker, L., Tuomilehto, J., Wei, Y., Yang, W., Wang, D., Hu, D., Pan, C., ACE Study Group, (2017) Effects of acarbose on cardiovascular and diabetes outcomes in patients with coronary heart disease and impaired glucose tolerance (ACE): a randomised, double-blind, placebo-controlled trial. Lancet Diabetes and Endocrinology, 5, pp. 877-886. (doi: 10.1016/S2213-8587(17)30309-1)
Wong, C. M., Hawkins, N. M., Ezekowitz, J. A., Jhund, P. S., Savu, A., MacDonald, M. R., Kristensen, S. L., Petrie, M. C., McMurray, J. J.V., McAlister, F. A., Kaul, P. (2017) Heart failure in young adults is associated with high mortality: a contemporary population-level analysis. Canadian Journal of Cardiology, 33, pp. 1472-1477. (doi: 10.1016/j.cjca.2017.05.009)
MacDonald, E. A., Stoyek, M. R., Rose, R. A., Quinn, T. A. (2017) Intrinsic regulation of sinoatrial node function and the zebrafish as a model of stretch effects on pacemaking. Progress in Biophysics and Molecular Biology, 130, pp. 198-211. (doi: 10.1016/j.pbiomolbio.2017.07.012)
McDonald, M. A., Ashley, E. A., Fedak, P. W.M., Hawkins, N., Januzzi, J. L., McMurray, J. J.V., Parikh, V. N., Rao, V., Svystonyuk, D., Teerlink, J. R., Virani, S. (2017) Mind the gap: current challenges and future state of heart failure care. Canadian Journal of Cardiology, 33, pp. 1434-1449. (doi: 10.1016/j.cjca.2017.08.023)
Stewart, S., Keates, A. K., Redfern, A., McMurray, J. J.V. (2017) Seasonal variations in cardiovascular disease. Nature Reviews Cardiology, 14, pp. 654-664. (doi: 10.1038/nrcardio.2017.76)
Welsh, P., Grassia, G., Botha, S., Sattar, N., Maffia, P. (2017) Targeting inflammation to reduce cardiovascular disease risk: a realistic clinical prospect? British Journal of Pharmacology, 174, pp. 3898-3913. (doi: 10.1111/bph.13818)
Mogensen, U. M., Jhund, P. S., Abraham, W. T., Desai, A. S., Dickstein, K., Packer, M., Rouleau, J. L., Solomon, S. D., Swedberg, K., Zile, M. R., Køber, L., McMurray, J. J.V. (2017) Type of atrial fibrillation and clinical outcomes in patients with heart failure and reduced ejection fraction. Journal of the American College of Cardiology, 70, pp. 2490-2500. (doi: 10.1016/j.jacc.2017.09.027)
Rutherford, E., Mangion, K., Mccomb, C., Bell, E., Cockburn, S., Talle, M., Roditi, G., Welsh, P., Woodward, R., Radjenovic, A., Struthers, A. D., Jardine, A., Berry, C., Patel, R. K., Mark, P. B. (2017) Myocardial changes in incident haemodialysis patients over 6-months: an observational cardiac magnetic resonance imaging study. Scientific Reports, 7, (doi: 10.1038/s41598-017-14481-y)
Kobayashi, Y., Johnson, N. P., Zimmermann, F. M., Witt, N., Berry, C., Jeremias, A., Koo, B.-K., Esposito, G., Rioufol, G., Park, S.-J., Nishi, T., Choi, D.-H., Oldroyd, K. G., Barbato, E., Pijls, N. H. J., De Bruyne, B., Fearon, W. F. (2017) Agreement of the resting distal to aortic coronary pressure with the instantaneous wave-free ratio. Journal of the American College of Cardiology, 70, pp. 2105-2113. (doi: 10.1016/j.jacc.2017.08.049)
Bayes-Genis, A., Núñez, J., Zannad, F., Ferreira, J. P., Anker, S. D., Cleland, J. G., Dickstein, K., Filippatos, G., Lang, C. C., Ng, L. L., Ponikowski, P., Samani, N. J., van Veldhuisen, D. J., Zwinderman, A. H., Metra, M., Lupón, J., Voors, A. A. (2017) The PCSK9-LDL receptor axis and outcomes in heart failure: BIOSTAT-CHF subanalysis. Journal of the American College of Cardiology, 70, pp. 2128-2136. (doi: 10.1016/j.jacc.2017.08.057)
Gao, H., Mangion, K., Carrick, D., Husmeier, D., Luo, X., Berry, C. (2017) Estimating prognosis in patients with acute myocardial infarction using personalized computational heart models. Scientific Reports, 7, (doi: 10.1038/s41598-017-13635-2)
Wolsk, E., Claggett, B., Diaz, R., Dickstein, K., Gerstein, H. C., Køber, L., Lawson, F. C., Lewis, E. F., Maggioni, A. P., McMurray, J. J.V., Probstfield, J. L., Riddle, M. C., Solomon, S. D., Tardif, J.-C., Pfeffer, M. A. (2017) Increases in natriuretic peptides precede heart failure hospitalization in patients with a recent coronary event and type 2 diabetes mellitus. Circulation, 136, pp. 1560-1562. (doi: 10.1161/CIRCULATIONAHA.117.029503)
Sharma, A., Demissei, B. G., Tromp, J., Hillege, H. L., Cleland, J. G.F., O'Connor, C. M., Metra, M., Ponikowski, P., Teerlink, J. R., Davison, B. A., Givertz, M. M., Bloomfield, D. M., Dittrich, H., van Veldhuisen, D. J., Cotter, G., Ezekowitz, J. A., Khan, M. A.F., Voors, A. A. (2017) A network analysis to compare biomarker profiles in patients with and without diabetes mellitus in acute heart failure. European Journal of Heart Failure, 19, pp. 1310-1320. (doi: 10.1002/ejhf.912)
Stevens, K., Denby, L., Patel, R. K., Mark, P. B., Kettlewell, S., Smith, G. L., Clancy, M. J., Delles, C., Jardine, A. G. (2017) Deleterious effects of phosphate on vascular and endothelial function via disruption to the nitric oxide pathway. Nephrology Dialysis Transplantation, 32, pp. 1617-1627. (doi: 10.1093/ndt/gfw252)
Charytan, D. M., Solomon, S. D., Ivanovich, P., Remuzzi, G., Cooper, M. E., McGill, J. B., Parving, H.-H., Parfrey, P., Singh, A. K., Burdmann, E. A., Levey, A. S., de Zeeuw, D., Eckardt, K.-U., McMurray, J. J.V., Claggett, B., Lewis, E. F., Pfeffer, M. A. (2017) ESRD after heart failure, myocardial infarction, or stroke in type 2 diabetic patients with CKD. American Journal of Kidney Diseases, 70, pp. 522-531. (doi: 10.1053/j.ajkd.2017.04.018)
Nishi, T., Johnson, N. P., De Bruyne, B., Berry, C., Gould, K. L., Jeremias, A., Oldroyd, K. G., Kobayashi, Y., Choi, D.-H., Pijls, N. H.J., Fearon, W. F. (2017) Influence of contrast media dose and osmolality on the diagnostic performance of contrast fractional flow reserve. Circulation: Cardiovascular Interventions, 10, (doi: 10.1161/CIRCINTERVENTIONS.117.004985)
White, S. L., Pasupathy, D., Sattar, N., Nelson, S. M., Lawlor, D. A., Briley, A. L., Seed, P. T., Welsh, P., Poston, L. (2017) Metabolic profiling of gestational diabetes in obese women during pregnancy. Diabetologia, 60, pp. 1903-1912. (doi: 10.1007/s00125-017-4380-6)
Ferreira, J. P., Rossignol, P., Machu, J.-L., Sharma, A., Girerd, N., Anker, S. D., Cleland, J. G., Dickstein, K., Filippatos, G., Hillege, H. L., Lang, C. C., Ter Maaten, J., Metra, M., Ng, L., Ponikowski, P., Samani, N. J., van Veldhuisen, D. J., Zwinderman, A. H., Voors, A., Zannad, F. (2017) Mineralocorticoid receptor antagonist pattern of use in heart failure with reduced ejection fraction: findings from BIOSTAT-CHF. European Journal of Heart Failure, 19, pp. 1284-1293. (doi: 10.1002/ejhf.900)
Gao, H., Qi, N., Feng, L., Ma, X., Danton, M., Berry, C., Luo, X. (2017) Modelling mitral valvular dynamics–current trend and future directions. International Journal for Numerical Methods in Biomedical Engineering, 33, (doi: 10.1002/cnm.2858)
Nassif, M. E., Tang, Y., Cleland, J. G.F., Abraham, W. T., Linde, C., Gold, M. R., Young, J. B., Daubert, J. C., Sherfesee, L., Schaber, D., Tang, A. S.L., Jones, P. G., Arnold, S. V., Spertus, J. A. (2017) Precision medicine for cardiac resynchronization: predicting quality of life benefits for individual patients-an analysis from 5 clinical trials. Circulation: Heart Failure, 10, (doi: 10.1161/CIRCHEARTFAILURE.117.004111)
Kristensen, S. L., Jhund, P. S., Mogensen, U. M., Rørth, R., Abraham, W. T., Desai, A., Dickstein, K., Rouleau, J. L., Zile, M. R., Swedberg, K., Packer, M., Solomon, S. D., Køber, L., McMurray, J. J.V. (2017) Prognostic value of N-terminal pro-B-type natriuretic peptide levels in heart failure patients with and without atrial fibrillation. Circulation: Heart Failure, 10, (doi: 10.1161/CIRCHEARTFAILURE.117.004409)
Cleland, J. G.F., Halliday, B. P., Prasad, S. K. (2017) Selecting patients with nonischemic dilated cardiomyopathy for ICDs. Journal of the American College of Cardiology, 70, pp. 1228-1231. (doi: 10.1016/j.jacc.2017.07.748)
Peterzan, M. A., Lygate, C. A., Neubauer, S., Rider, O. J. (2017) Metabolic remodeling in hypertrophied and failing myocardium: a review. American Journal of Physiology: Heart and Circulatory Physiology, 313, pp. H597-H616. (doi: 10.1152/ajpheart.00731.2016)
Gao, H., Feng, L., Qi, N., Berry, C., Griffith, B. E., Luo, X. (2017) A coupled mitral valve - left ventricle model with fluid-structure interaction. Medical Engineering and Physics, 47, pp. 128-136. (doi: 10.1016/j.medengphy.2017.06.042)
Lu, H.R., Hortigon-Vinagre, M.P., Zamora, V., Kopljar, I., De Bondt, A., Gallacher, D.J., Smith, G. (2017) Application of optical action potentials in human induced pluripotent stem cells-derived cardiomyocytes to predict drug-induced cardiac arrhythmias. Journal of Pharmacological and Toxicological Methods, 87, pp. 53-67. (doi: 10.1016/j.vascn.2017.05.001)
Fröhlich, H., Torres, L., Täger, T., Schellberg, D., Corletto, A., Kazmi, S., Goode, K., Grundtvig, M., Hole, T., Katus, H. A., Cleland, J. G.F., Atar, D., Clark, A. L., Agewall, S., Frankenstein, L. (2017) Bisoprolol compared with carvedilol and metoprolol succinate in the treatment of patients with chronic heart failure. Clinical Research in Cardiology, 106, pp. 711-721. (doi: 10.1007/s00392-017-1115-0)
Wannamethee, S. G., Welsh, P., Papacosta, O., Ellins, E. A., Halcox, J. P.J., Whincup, P. H., Sattar, N. (2017) Circulating soluble receptor for advanced glycation end product: cross-sectional associations with cardiac markers and subclinical vascular disease in older men with and without diabetes. Atherosclerosis, 264, pp. 36-43. (doi: 10.1016/j.atherosclerosis.2017.07.008)
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Miro, Ò., Peacock, F. W., McMurray, J. J., Bueno, H., Christ, M., Maisel, A. S., Cullen, L., Cowie, M. R., Di Somma, S., Martin Sanchez, F. J., Platz, E., Masip, J., Zeymer, U., Vrints, C., Price, S., Mebazaa, A., Mueller, C. (2017) European Society of Cardiology - Acute Cardiovascular Care Association position paper on safe discharge of acute heart failure patients from the emergency department. European Heart Journal: Acute Cardiovascular Care, 6, pp. 311-320. (doi: 10.1177/2048872616633853)
Harumi Higuchi dos Santos, M., Sharma, A., Sun, J.‐L., Pieper, K., McMurray, J. J.V., Holman, R. R., Lopes, R. D. (2017) International variation in outcomes among people with cardiovascular disease or cardiovascular risk factors and impaired glucose tolerance: insights from the NAVIGATOR Trial. Journal of the American Heart Association, 6, (doi: 10.1161/JAHA.116.003892)
Arain, F., Gullestad, L., Nymo, S., Kjekshus, J., Cleland, J. G.F., Michelsen, A., McMurray, J. J.V., Wikstrand, J., Aukrust, P., Ueland, T. (2017) Low YKL-40 in Chronic Heart Failure may predict beneficial effects of statins: Analysis from the Controlled Rosuvastatin Multinational Trial in Heart Failure (CORONA) Biomarkers, 22, pp. 261-267. (doi: 10.1080/1354750X.2016.1204003)
2016
Torabi, A., Cleland, J. G.F., Sherwi, N., Atkin, P., Panahi, H., Kilpatrick, E., Thackray, S., Hoye, A., Alamgir, F., Goode, K., Rigby, A., Clark, A. L. (2016) Influence of case definition on incidence and outcome of acute coronary syndromes. Open Heart, 3, (doi: 10.1136/openhrt-2016-000487)
Khder, Y., Shi, V., McMurray, J. J.V., Lefkowitz, M. P. (2016) Sacubitril/valsartan (LCZ696) in heart failure. Springer
Fattah, C., Nather, K., McCarroll, C. S., Hortigon-Vinagre, M. P., Zamora Rodriguez, V., Flores-Munoz, M., McArthur, L., Zentilin, L., Giacca, M., Touyz, R. M., Smith, G. L., Loughrey, C. M., Nicklin, S. A. (2016) Gene therapy with Angiotensin-(1-9) preserves left ventricular systolic function after myocardial infarction. Journal of the American College of Cardiology, 68, pp. 2652-2666. (doi: 10.1016/j.jacc.2016.09.946)
Mangion, K., Gao, H., Mccomb, C., Carrick, D., Clerfond, G., Zhong, X., Luo, X., Haig, C., Berry, C. (2016) A novel method for estimating myocardial strain: assessment of deformation tracking against reference magnetic resonance methods in healthy volunteers. Scientific Reports, 6, (doi: 10.1038/srep38774)
Huethorst, E., Hortigon, M., Zamora-Rodriguez, V., Reynolds, P.M., Burton, F., Smith, G., Gadegaard, N. (2016) Enhanced human-induced pluripotent stem cell derived cardiomyocyte maturation using a dual microgradient substrate. ACS Biomaterials Science and Engineering, 2, pp. 2231-2239. (doi: 10.1021/acsbiomaterials.6b00426)
Kobayashi, Y., Johnson, N. P., Berry, C., De Bruyne, B., Gould, K. L., Jeremias, A., Oldroyd, K. G., Pijls, N. H.J., Fearon, W. F. (2016) The influence of lesion location on the diagnostic accuracy of adenosine-free coronary pressure wire measurements. JACC: Cardiovascular Interventions, 9, pp. 2390-2399. (doi: 10.1016/j.jcin.2016.08.041)
Teerlink, J. R., Felker, G. M., McMurray, J. J.V., Solomon, S. D., Adams, Jr., K. F., Cleland, J. G.F., Ezekowitz, J. A., Goudev, A., Macdonald, P., Metra, M., Mitrovic, V., Ponikowski, P., Serpytis, P., Spinar, J., Tomcsányi, J., Vandekerckhove, H. J., Voors, A. A., Monsalvo, M. L., Johnston, J., Malik, F. I., Honarpour, N. (2016) Chronic oral study of myosin activation to increase contractility in heart failure (COSMIC-HF): a phase 2, pharmacokinetic, randomised, placebo-controlled trial. Lancet, 388, pp. 2895-2903. (doi: 10.1016/S0140-6736(16)32049-9)
White, S. L., Lawlor, D. A., Briley, A. L., Godfrey, K. M., Nelson, S. M., Oteng-Ntim, E., Robson, S. C., Sattar, N., Seed, P. T., Vieira, M. C., Welsh, P., Whitworth, M., Poston, L., Pasupathy, D. (2016) Early antenatal prediction of gestational diabetes in obese women: development of prediction tools for targeted intervention. PLoS ONE, 11, (doi: 10.1371/journal.pone.0167846)
Carrick, D., Haig, C., Ahmed, N., Carberry, J., Teng Yue May, V., McEntegart, M., Petrie, M. C., Eteiba, H., Lindsay, M., Hood, S., Watkins, S., Davies, A., Abouzaid, A. M., Mordi, I., Ford, I., Radjenovic, A., Oldroyd, K. G., Berry, C. (2016) Comparative prognostic utility of indexes of microvascular function alone or in combination in patients with an acute ST-segment elevation myocardial infarction. Circulation, 134, pp. 1833-1847. (doi: 10.1161/CIRCULATIONAHA.116.022603)
Zile, M. R., Claggett, B. L., Prescott, M. F., McMurray, J. J.V., Packer, M., Rouleau, J. L., Swedberg, K., Desai, A. S., Gong, J., Shi, V. C., Solomon, S. D. (2016) Prognostic implications of changes in N-terminal pro-B-type natriuretic peptide in patients with heart failure. Journal of the American College of Cardiology, 68, pp. 2425-2436. (doi: 10.1016/j.jacc.2016.09.931)
Teh, I., McClymont, D., Zdora, M.-C., Whittington, H. J., Davidoiu, V., Lee, J., Lygate, C. A., Rau, C., Zanette, I., Schneider, J. E. (2016) Validation of diffusion tensor MRI measurements of cardiac microstructure with structure tensor synchrotron radiation imaging. Journal of Cardiovascular Magnetic Resonance, 19, (doi: 10.1186/s12968-017-0342-x)
Vegter, E. L., Schmitter, D., Hagemeijer, Y., Ovchinnikova, E. S., van der Harst, P., Teerlink, J. R., O'Connor, C. M., Metra, M., Davison, B. A., Bloomfield, D., Cotter, G., Cleland, J. G.F., Givertz, M. M., Ponikowski, P., van Veldhuisen, D. J., van der Meer, P., Berezikov, E., Voors, A. A., Khan, M. A.F. (2016) Use of biomarkers to establish potential role and function of circulating microRNAs in acute heart failure. International Journal of Cardiology, 224, pp. 231-239. (doi: 10.1016/j.ijcard.2016.09.010)
Ponikowski, P. et al. (2016) 2016 ESC guidelines for the diagnosis and treatment of acute and chronic heart failure [Guía ESC 2016 sobre el diagnóstico y tratamiento de la insuficiencia cardiaca aguda y crónica] Revista Española de Cardiología, 69, pp. 1167.e1-1167.e85. (doi: 10.1016/j.recesp.2016.10.014)
Zak, J. et al. (2016) ASPP2 deficiency causes features of 1q41q42 microdeletion syndrome. Cell Death and Differentiation, 23, pp. 1973-1984. (doi: 10.1038/cdd.2016.76)
Mc Causland, F. R., Claggett, B., Burdmann, E. A., Eckardt, K.-U., Kewalramani, R., Levey, A. S., McMurray, J. J.V., Parfrey, P., Remuzzi, G., Singh, A. K., Solomon, S. D., Toto, R. D., Pfeffer, M. A. (2016) C-Reactive protein and risk of ESRD: results from the Trial to Reduce Cardiovascular Events With Aranesp Therapy (TREAT) American Journal of Kidney Diseases, 68, pp. 873-881. (doi: 10.1053/j.ajkd.2016.07.022)
Pellicori, P., Cleland, J. G.F., Zhang, J., Kallvikbacka-Bennett, A., Urbinati, A., Shah, P., Kazmi, S., Clark, A. L. (2016) Cardiac dysfunction, congestion and loop diuretics: their relationship to prognosis in heart failure. Cardiovascular Drugs and Therapy, 30, pp. 599-609. (doi: 10.1007/s10557-016-6697-7)
Nagaraja, V., Ooi, S.-Y., Nolan, J., Large, A., De Belder, M., Ludman, P., Bagur, R., Curzen, N., Matsukage, T., Yoshimachi, F., Kwok, C. S., Berry, C., Mamas, M. A. (2016) Impact of incomplete percutaneous revascularization in patients With multivessel coronary artery disease: a systematic review and meta-analysis. Journal of the American Heart Association, 5, (doi: 10.1161/JAHA.116.004598)
Kaye, D. M., Hasenfuß, G., Neuzil, P., Post, M. C., Doughty, R., Trochu, J.-N., Kolodziej, A., Westenfeld, R., Penicka, M., Rosenberg, M., Walton, A., Muller, D., Walters, D., Hausleiter, J., Raake, P., Petrie, M. C., Bergmann, M., Jondeau, G., Feldman, T., van Veldhuisen, D. J., Ponikowski, P., Silvestry, F. E., Burkhoff, D., Hayward, C. (2016) One-year outcomes after transcatheter insertion of an interatrial shunt device for the management of heart failure with preserved ejection fraction. Circulation: Heart Failure, 9, (doi: 10.1161/CIRCHEARTFAILURE.116.003662)
Hortigon-Vinagre, M.P., Zamora, V., Burton, F.L., Green, J., Gintant, G.A., Smith, G.L. (2016) The use of ratiometric fluorescence measurements of the voltage sensitive dye Di-4-ANEPPS to examine action potential characteristics and drug effects on human induced pluripotent stem cell-derived cardiomyocytes. Toxicological Sciences, 154, pp. 320-331. (doi: 10.1093/toxsci/kfw171)
Pitts, R., Gunzburger, E., Ballantyne, C. M., Barter, P. J., Kallend, D., Leiter, L. A., Leitersdorf, E., McMurray, J. J.V., Nicholls, S. J., Niesor, E. J., Olsson, A. G., Shah, P. K., Tardif, J.-C., Kittelson, J., Schwartz, G. G. (2016) Treatment with Dalcetrapib modifies the relationship between high-density lipoprotein cholesterol and C-reactive protein. Journal of the American College of Cardiology, 68, pp. 2488-2490. (doi: 10.1016/j.jacc.2016.09.932)
Damman, K., Solomon, S. D., Pfeffer, M. A., Swedberg, K., Yusuf, S., Young, J. B., Rouleau, J. L., Granger, C. B., McMurray, J. J.V. (2016) Worsening renal function and outcome in heart failure patients with reduced and preserved ejection fraction and the impact of angiotensin receptor blocker treatment: data from the CHARM-study programme. European Journal of Heart Failure, 18, pp. 1508-1517. (doi: 10.1002/ejhf.609)
Napp, A. E. et al. (2016) Computed tomography versus invasive coronary angiography: design and methods of the pragmatic randomised multicentre DISCHARGE trial. European Radiology, 27, pp. 2957-2968. (doi: 10.1007/s00330-016-4620-z)
Inglis, S. C., Clark, R. A., Dierckx, R., Prieto-Merino, D., Cleland, J. G.F. (2016) Structured telephone support or non-invasive telemonitoring for patients with heart failure. Heart, 103, pp. 255-257. (doi: 10.1136/heartjnl-2015-309191)
Demissei, B. G., Postmus, D., Liu, L. C.Y., Cleland, J. G.F., O'Connor, C. M., Metra, M., Ponikowski, P., Teerlink, J. R., Cotter, G., Davison, B. A., Edwards, C., Givertz, M. M., Bloomfield, D. M., Dittrich, H. C., Voors, A. A., Hillege, H. L. (2016) Risk-based evaluation of efficacy of rolofylline in patients hospitalized with acute heart failure — Post-hoc analysis of the PROTECT trial. International Journal of Cardiology, 223, pp. 967-975. (doi: 10.1016/j.ijcard.2016.08.271)
Ferreira, J. P., Girerd, N., Pellicori, P., Duarte, K., Girerd, S., Pfeffer, M. A., McMurray, J. J.V., Pitt, B., Dickstein, K., Jacobs, L., Staessen, J. A., Butler, J., Latini, R., Masson, S., Mebazaa, A., Rocca, H. P. B.-L., Delles, C., Heymans, S., Sattar, N., Jukema, J. W., Cleland, J. G.F., Zannad, F., Rossignol, P. (2016) Renal function estimation and Cockroft–Gault formulas for predicting cardiovascular mortality in population-based, cardiovascular risk, heart failure and post-myocardial infarction cohorts: the Heart ‘OMics’ in AGEing (HOMAGE) and the high-risk myocardial infarction database initiatives. BMC Medicine, 14, (doi: 10.1186/s12916-016-0731-2)
Jhund, P. S. (2016) Geographic variation in heart failure - a matter of celebration or condemnation? European Journal of Heart Failure, 18, pp. 1329-1330. (doi: 10.1002/ejhf.652)
Pfeffer, M. A., McMurray, J. J.V. (2016) Lessons in uncertainty and humility — Clinical trials involving hypertension. New England Journal of Medicine, 375, pp. 1756-1766. (doi: 10.1056/NEJMra1510067)
Weinberger, F., Breckwoldt, K., Pecha, S., Kelly, A., Geertz, B., Starbatty, J., Yorgan, T., Cheng, K.-H., Lessmann, K., Stolen, T., Scherrer-Crosbie, M., Smith, G., Reichenspurner, H., Hansen, A., Eschenhagen, T. (2016) Cardiac repair in guinea pigs with human engineered heart tissue from induced pluripotent stem cells. Science Translational Medicine, 8, pp. 363ra148-363ra148. (doi: 10.1126/scitranslmed.aaf8781)
Martín-Sánchez, F. J., Christ, M., Miró, Ò., Peacock, W. F., McMurray, J. J., Bueno, H., Maisel, A. S., Cullen, L., Cowie, M. R., Di Somma, S., Platz, E., Masip, J., Zeymer, U., Vrints, C., Price, S., Mueller, C. (2016) Practical approach on frail older patients attended for acute heart failure. International Journal of Cardiology, 222, pp. 62-71. (doi: 10.1016/j.ijcard.2016.07.151)
Bekfani, T., Pellicori, P., Morris, D. A., Ebner, N., Valentova, M., Steinbeck, L., Wachter, R., Elsner, S., Sliziuk, V., Schefold, J. C., Sandek, A., Doehner, W., Cleland, J. G.F., Lainscak, M., Anker, S. D., von Haehling, S. (2016) Sarcopenia in patients with heart failure with preserved ejection fraction: impact on muscle strength, exercise capacity and quality of life. International Journal of Cardiology, 222, pp. 41-46. (doi: 10.1016/j.ijcard.2016.07.135)
Petrie, M. C., Jhund, P. S., She, L., Adlbrecht, C., Doenst, T., Panza, J. A., Hill, J. A., Lee, K. L., Rouleau, J. L., Prior, D. L., Ali, I. S., Maddury, J., Golba, K. S., White, H. D., Carson, P., Chrzanowski, L., Romanov, A., Miller, A. B., Velazquez, E. J. (2016) Ten-year outcomes after coronary artery bypass grafting according to age in patients with heart failure and left ventricular systolic dysfunction: an analysis of the extended follow-up of the STICH Trial (Surgical Treatment for Ischemic Heart Failure) Circulation, 134, pp. 1314-1324. (doi: 10.1161/CIRCULATIONAHA.116.024800)
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Hennigan, B., Oldroyd, K. G., Berry, C., Johnson, N., McClure, J., McCartney, P., McEntegart, M. B., Eteiba, H., Petrie, M. C., Rocchiccioli, P., Good, R., Lindsay, M. M., Hood, S., Watkins, S. (2016) Discordance between resting and hyperemic indices of coronary stenosis severity: the VERIFY 2 study (a comparative study of resting coronary pressure gradient, instantaneous wave-free ratio and fractional flow reserve in an unselected population referred for invasive angiography) Circulation: Cardiovascular Interventions, 9, (doi: 10.1161/CIRCINTERVENTIONS.116.004016)
Welsh, P., Tuckwell, K., McInnes, I. B., Sattar, N. (2016) Effect of IL-6 receptor blockade on high-sensitivity troponin T and NT-proBNP in rheumatoid arthritis. Atherosclerosis, 254, pp. 167-171. (doi: 10.1016/j.atherosclerosis.2016.10.016)
Preiss, D., Rankin, N., Welsh, P., Holman, R.R., Kangas, A.J., Soininen, P., Würtz, P., Ala-Korpela, M., Sattar, N. (2016) Effect of metformin therapy on circulating amino acids in a randomized trial: the CAMERA study. Diabetic Medicine, 33, pp. 1569-1574. (doi: 10.1111/dme.13097)
Savarese, G., Giugliano, R. P., Rosano, G. M.C., McMurray, J., Magnani, G., Filippatos, G., Dellegrottaglie, S., Lund, L. H., Trimarco, B., Perrone-Filardi, P. (2016) Efficacy and safety of novel oral anticoagulants in patients with atrial fibrillation and heart failure: a meta-analysis. JACC: Heart Failure, 4, pp. 881-884. (doi: 10.1016/j.jchf.2016.07.012)
Sirker, A., Kwok, C. S., Kotronias, R., Bagur, R., Bertrand, O., Butler, R., Berry, C., Nolan, J., Oldroyd, K., Mamas, M. (2016) Influence of access site choice for cardiac catheterization on risk of adverse neurological events: A systematic review and meta-analysis. American Heart Journal, 181, pp. 107-119. (doi: 10.1016/j.ahj.2016.06.027)
Mangion, K., Clerfond, G., Mccomb, C., Carrick, D., Rauhalammi, S. M., McClure, J., Corcoran, D. S., Woodward, R., Orchard, V., Radjenovic, A., Zhong, X., Berry, C. (2016) Myocardial strain in healthy adults across a broad age range as revealed by cardiac magnetic resonance imaging at 1.5 and 3.0T: associations of myocardial strain with myocardial region, age, and sex. Journal of Magnetic Resonance Imaging, 44, pp. 1197-1205. (doi: 10.1002/jmri.25280)
Ahmed, N., Carberry, J., Teng, V., Carrick, D., Berry, C. (2016) Risk assessment in patients with an acute ST-elevation myocardial infarction. Journal of Comparative Effectiveness Research, 5, pp. 581-593. (doi: 10.2217/cer-2016-0017)
Crocini, C., Ferrantini, C., Coppini, R., Scardigli, M., Yan, P., Loew, L. M., Smith, G., Cerbai, E., Poggesi, C., Pavone, F. S., Sacconi, L. (2016) Optogenetics design of mechanistically-based stimulation patterns for cardiac defibrillation. Scientific Reports, 6, (doi: 10.1038/srep35628)
Tromp, J., Meyer, S., Mentz, R. J., O'Connor, C. M., Metra, M., Dittrich, H. C., Ponikowski, P., Teerlink, J. R., Cotter, G., Davison, B., Cleland, J. G.F., Givertz, M. M., Bloomfield, D. M., van Veldhuisen, D. J., Hillege, H. L., Voors, A. A., van der Meer, P. (2016) Acute heart failure in the young: clinical characteristics and biomarker profiles. International Journal of Cardiology, 221, pp. 1067-1072. (doi: 10.1016/j.ijcard.2016.06.339)
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Solomon, S. D., Claggett, B., McMurray, J. J.V., Hernandez, A. F., Fonarow, G. C. (2016) Combined neprilysin and renin-angiotensin system inhibition in heart failure with reduced ejection fraction: a meta-analysis. European Journal of Heart Failure, 18, pp. 1238-1243. (doi: 10.1002/ejhf.603)
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Solomon, S. D., Claggett, B., Packer, M., Desai, A., Zile, M. R., Swedberg, K., Rouleau, J., Shi, V., Lefkowitz, M., McMurray, J. J.V. (2016) Efficacy of sacubitril/valsartan relative to a prior decompensation: the PARADIGM-HF trial. JACC: Heart Failure, 4, pp. 816-822. (doi: 10.1016/j.jchf.2016.05.002)
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Cannon, J. A., Shen, L., Jhund, P., Anand, I. S., Komajda, M., McKelvie, R. S., Zile, M. R., Carson, P. E., McMurray, J. J. V. (2016) Clinical outcomes according to QRS duration and morphology in the irbesartan in patients with heart failure and preserved systolic function (I-Preserve) trial. European Journal of Heart Failure, 18, pp. 1021-1031. (doi: 10.1002/ejhf.547)
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Emdin, C. A., Conrad, N., Kiran, A., Salimi-Khorshidi, G., Woodward, M., Anderson, S. G., Mohseni, H., Dargie, H. J., Hardman, S. M.C., McDonagh, T., McMurray, J. J.V., Cleland, J. G.F., Rahimi, K. (2016) Variation in hospital performance for heart failure management in the National Heart Failure Audit for England and Wales. Heart, 103, pp. 55-62. (doi: 10.1136/heartjnl-2016-309706)
2015
Cannon, J. A., McKean, A. R., Jhund, P. S., McMurray, J. J.V. (2015) What can we learn from RELAX-AHF compared to previous AHF trials and what does the future hold? Open Heart, 2, (doi: 10.1136/openhrt-2015-000283)
Cleland, J. G.F., Mareev, Y. (2015) CRT for heart failure and ESRD: more trials or more thought needed? Journal of the American College of Cardiology, 66, pp. 2630-2632. (doi: 10.1016/j.jacc.2015.10.022)
Pocock, S. J., McMurray, J. J.V., Collier, T. J. (2015) Statistical controversies in reporting of clinical trials: part 2 of a 4-part series on statistics for clinical trials. Journal of the American College of Cardiology, 66, pp. 2648-62. (doi: 10.1016/j.jacc.2015.10.023)
Pocock, S. J., McMurray, J. J.V., Collier, T. J. (2015) Making sense of statistics in clinical trial reports: Part 1 of a 4-part series on statistics for clinical trials. Journal of the American College of Cardiology, 66, pp. 2536-2549. (doi: 10.1016/j.jacc.2015.10.014)
Claggett, B., Packer, M., McMurray, J. J.V., Swedberg, K., Rouleau, J., Zile, M. R., Jhund, P., Lefkowitz, M., Shi, V., Solomon, S. D. (2015) Estimating the long-term treatment benefits of Sacubitril–Valsartan. New England Journal of Medicine, 373, pp. 2289-2290. (doi: 10.1056/NEJMc1509753)
Gheorghiade, M., Greene, S. J., Butler, J., Filippatos, G., Lam, C. S. P., Maggioni, A. P., Ponikowski, P., Shah, S. J., Solomon, S. D., Kraigher-Krainer, E., Samano, E. T., Müller, K., Roessig, L., Pieske, B., McMurray, J., for the SOCRATES-REDUCED Investigators and Coordinators, . (2015) Effect of vericiguat, a soluble guanylate cyclase stimulator, on natriuretic peptide levels in patients with worsening chronic heart failure and reduced ejection fraction. JAMA: Journal of the American Medical Association, 314, pp. 2251-2262. (doi: 10.1001/jama.2015.15734)
Berry, C., Corcoran, D., Hennigan, B., Watkins, S., Layland, J., Oldroyd, K. G. (2015) Fractional flow reserve-guided management in stable coronary disease and acute myocardial infarction: recent developments. European Heart Journal, 36, pp. 3155-3164. (doi: 10.1093/eurheartj/ehv206)
Nam, J., Briggs, A., Layland, J., Oldroyd, K. G., Curzen, N., Sood, A., Balachandran, K., Das, R., Junejo, S., Eteiba, H., Petrie, M. C., Lindsay, M., Watkins, S., Corbett, S., O'Rourke, B., O'Donnell, A., Stewart, A., Hannah, A., McConnachie, A., Henderson, R., Berry, C. (2015) Fractional flow reserve (FFR) versus angiography in guiding management to optimise outcomes in non-ST segment elevation myocardial infarction (FAMOUS-NSTEMI) developmental trial: cost-effectiveness using a mixed trial- and model-based methods. Cost Effectiveness and Resource Allocation, 2015, (doi: 10.1186/s12962-015-0045-9)
McMurray, J. J.J.V. (2015) Improving outcomes in heart failure: a personal perspective. European Heart Journal, 36, pp. 3467-3470. (doi: 10.1093/eurheartj/ehv565)
Pfeffer, M. A., Claggett, B., Diaz, R., Dickstein, K., Gerstein, H. C., Køber, L. V., Lawson, F. C., Ping, L., Wei, X., Lewis, E. F., Maggioni, A. P., McMurray, J. J.V., Probstfield, J. L., Riddle, M. C., Solomon, S. D., Tardif, J.-C. (2015) Lixisenatide in patients with type 2 diabetes and acute coronary syndrome. New England Journal of Medicine, 373, pp. 2247-2257. (doi: 10.1056/NEJMoa1509225)
Gao, H., Li, W.G., Cai, L., Berry, C., Luo, X.Y. (2015) Parameter estimation in a Holzapfel–Ogden law for healthy myocardium. Journal of Engineering Mathematics, 95, pp. 231-248. (doi: 10.1007/s10665-014-9740-3)
Zinman, B., Wanner, C., Lachin, J. M., Fitchett, D., Bluhmki, E., Hantel, S., Mattheus, M., Devins, T., Johansen, O. E., Woerle, H. J., Broedl, U. C., Inzucchi, S. E., EMPA-REG OUTCOME Investigators, (2015) Empagliflozin, cardiovascular outcomes, and mortality in type 2 diabetes. New England Journal of Medicine, 373, pp. 2117-2128. (doi: 10.1056/NEJMoa1504720)
Layland, J., Nerlekar, N., Palmer, S., Berry, C., Oldroyd, K. (2015) Invasive assessment of the coronary microcirculation in the catheter laboratory. International Journal of Cardiology, 199, pp. 141-149. (doi: 10.1016/j.ijcard.2015.05.190)
Simpson, J., Jhund, P. S., Silva Cardoso, J., Martinez, F., Mosterd, A., Ramires, F., Rizkala, A. R., Senni, M., Squire, I., Gong, J., Lefkowitz, M. P., Shi, V. C., Desai, A. S., Rouleau, J. L., Swedberg, K., Zile, M. R., McMurray, J. J.V., Packer, M., Solomon, S. D. (2015) Comparing LCZ696 with Enalapril according to baseline risk using the MAGGIC and EMPHASIS-HF risk scores. Journal of the American College of Cardiology, 66, pp. 2059-2071. (doi: 10.1016/j.jacc.2015.08.878)
Jolicœur, E. M., Dunning, A., Castelvecchio, S., Dabrowski, R., Waclawiw, M. A., Petrie, M. C., Stewart, R., Jhund, P. S., Desvigne-Nickens, P., Panza, J. A., Bonow, R. O., Sun, B., San, T. R., Al-Khalidi, H. R., Rouleau, J. L., Velazquez, E. J., Cleland, J. G.F. (2015) Importance of angina in patients with coronary disease, heart failure, and left ventricular systolic dysfunction. Journal of the American College of Cardiology, 66, pp. 2092-2100. (doi: 10.1016/j.jacc.2015.08.882)
McMurray, J.J., Cowie, M.R., Cohen, A.A., Briggs, A., de Pouvourville, G., Taylor, M., Hancock, E., Trueman, D., Mumby-Croft, J., Haroun, R., Deschaseaux, C. (2015) A new cost-effectiveness modelling approach in chronic heart failure with reduced ejection fraction - PCV118. Value in Health, 18, (doi: 10.1016/j.jval.2015.09.887)
Aitken, E., Kerr, D., Geddes, C., Berry, C., Kingsmore, D. (2015) Cardiovascular changes occurring with occlusion of a mature arteriovenous fistula. Journal of Vascular Access, 16, pp. 459-466. (doi: 10.5301/jva.5000336)
Wang, N., Hung, C.-L., Shin, S.-H., Claggett, B., Skali, H., Thune, J. J., Køber, L., Shah, A., McMurray, J. J.V., Pfeffer, M. A., Solomon, S. D. (2015) Regional cardiac dysfunction and outcome in patients with left ventricular dysfunction, heart failure, or both after myocardial infarction. European Heart Journal, (doi: 10.1093/eurheartj/ehv558)
Bello, N. A., Lewis, E. F., Desai, A. S., Anand, I. S., Krum, H., McMurray, J. J.V., Olson, K., Solomon, S. D., Swedberg, K., van Veldhuisen, D. J., Young, J. B., Pfeffer, M. A. (2015) Increased risk of stroke with darbepoetin alfa in anaemic heart failure patients with diabetes and chronic kidney disease. European Journal of Heart Failure, 17, pp. 1201-1207. (doi: 10.1002/ejhf.412)
Simpson, J., Castagno, D., Doughty, R. N., Poppe, K. K., Earle, N., Squire, I., Richards, M., Andersson, B., Ezekowitz, J. A., Komajda, M., Petrie, M. C., McAlister, F. A., Gamble, G. D., Whalley, G. A., McMurray, J. J.V. (2015) Is heart rate a risk marker in patients with chronic heart failure and concomitant atrial fibrillation? Results from the MAGGIC meta-analysis. European Journal of Heart Failure, 17, pp. 1182-1191. (doi: 10.1002/ejhf.346)
Pellicori, P., Joseph, A. C., Zhang, J., Lukaschuk, E., Sherwi, N., Bourantas, C. V., Loh, H., Clark, A. L., Cleland, J. G.F. (2015) The relationship of QRS morphology with cardiac structure and function in patients with heart failure. Clinical Research in Cardiology, 104, pp. 935-945. (doi: 10.1007/s00392-015-0861-0)
Inglis, S. C., Clark, R. A., Dierckx, R., Prieto-Merino, D., Cleland, J. G.F. (2015) Structured telephone support or non-invasive telemonitoring for patients with heart failure. Cochrane Database of Systematic Reviews, 2015, (doi: 10.1002/14651858.CD007228.pub3)
Deng, L., Blanco Lopez, F. J., Stevens, H., Lu, R., Caudrillier, A., McBride, M., McClure, J. D., Grant, J., Thomas, M., Frid, M., Stenmark, K., White, K., Seto, A. G., Morrell, N. W., Bradshaw, A. C., MacLean, M. R., Baker, A. H. (2015) MicroRNA-143 activation regulates smooth muscle and endothelial cell crosstalk in pulmonary arterial hypertension. Circulation Research, 117, pp. 870-883. (doi: 10.1161/CIRCRESAHA.115.306806)
Jhund, P., Fu, M., Bayram, E., Chen, C.-H., Negrusz-Kawecka, M., Rosenthal, A., Desai, A. S., Lefkowitz, M. P., Rizkala, A. R., Rouleau, J. L., Shi, V. C., Solomon, S. D., Swedberg, K., Zile, M. R., McMurray, J. J.V., Packer, M. (2015) Efficacy and safety of LCZ696 (sacubitril-valsartan) according to age: insights from PARADIGM-HF. European Heart Journal, 36, pp. 2576-2584. (doi: 10.1093/eurheartj/ehv330)
Farag, M., Mabote, T., Shoaib, A., Zhang, J., Nabhan, A. F., Clark, A. L., Cleland, J. G. (2015) Hydralazine and nitrates alone or combined for the management of chronic heart failure: a systematic review. International Journal of Cardiology, 196, pp. 61-69. (doi: 10.1016/j.ijcard.2015.05.160)
Mareev, Y., Cleland, J. G.F. (2015) Should β-blockers be used in patients with heart failure and atrial fibrillation? Clinical Therapeutics, 37, pp. 2215-2224. (doi: 10.1016/j.clinthera.2015.08.017)
Shadman, R., Poole, J. E., Dardas, T. F., Mozaffarian, D., Cleland, J. G.F., Swedberg, K., Maggioni, A. P., Anand, I. S., Carson, P. E., Miller, A. B., Levy, W. C. (2015) A novel method to predict the proportional risk of sudden cardiac death in heart failure: derivation of the Seattle Proportional Risk Model. Heart Rhythm, 12, pp. 2069-2077. (doi: 10.1016/j.hrthm.2015.06.039)
Butcher, C., Mareev, Y., Markides, V., Mason, M., Wong, T., Cleland, J.G.F. (2015) Cardiac resynchronization therapy update: evolving indications, expanding benefit? Current Cardiology Reports, 17, (doi: 10.1007/s11886-015-0641-5)
Grodin, J. L., Perez, A. L., Wu, Y., Hernandez, A. F., Butler, J., Metra, M., Felker, G. M., Voors, A. A., McMurray, J. J., Armstrong, P. W., Califf, R. M., Starling, R. C., O'Connor, C. M., Tang, W.H. W. (2015) Circulating kidney injury molecule-1 levels in acute heart failure. JACC: Heart Failure, 3, pp. 777-785. (doi: 10.1016/j.jchf.2015.06.006)
Akehurst, C., Small, H., Sharafetdinova, L., Forrest, R., Beattie, W., Brown, C. E., Robinson, S. W., McClure, J. D., Work, L. M., Carty, D. M., McBride, M. W., Freeman, D. J., Delles, C. (2015) Differential expression of microRNA-206 and its target genes in pre-eclampsia. Journal of Hypertension, 33, pp. 2068-2074. (doi: 10.1097/HJH.0000000000000656)
Frankenstein, L., Fröhlich, H., Cleland, J. G.F. (2015) Multidisciplinary approach for patients hospitalized with heart failure. Revista Española de Cardiología (English Edition), 68, pp. 885-891. (doi: 10.1016/j.rec.2015.05.008)
Krum, H., McMurray, J. J.V., Abraham, W. T., Dickstein, K., Køber, L., Desai, A. S., Solomon, S. D., Chiang, Y., Gimpelewicz, C., Reimund, B., Ali, M. A., Tarnesby, G., Massie, B. M. (2015) The Aliskiren trial to minimize outcomes in patients with heart failure trial (ATMOSPHERE): revised statistical analysis plan and baseline characteristics. European Journal of Heart Failure, 17, pp. 1075-1083. (doi: 10.1002/ejhf.408)
Jhund, P., McMurray, J. J.V., Chaturvedi, N., Brunel, P., Desai, A. S., Finn, P. V., Haffner, S. M., Solomon, S. D., Weinrauch, L. A., Claggett, B. L., Pfeffer, M. A. (2015) Mortality following a cardiovascular or renal event in patients with type 2 diabetes in the ALTITUDE trial. European Heart Journal, 36, pp. 2463-2469. (doi: 10.1093/eurheartj/ehv295)
Cleland, J. G.F., Freemantle, N. (2015) QRS morphology as a predictor of the response to cardiac resynchronisation therapy: fact or fashion? Heart, 101, pp. 1441-1443. (doi: 10.1136/heartjnl-2015-307553)
Girerd, N., Collier, T., Pocock, S., Krum, H., McMurray, J. J., Swedberg, K., Van Veldhuisen, D. J., Vincent, J., Pitt, B., Zannad, F. (2015) Clinical benefits of eplerenone in patients with systolic heart failure and mild symptoms when initiated shortly after hospital discharge: analysis from the EMPHASIS-HF trial. European Heart Journal, 36, pp. 2310-2317. (doi: 10.1093/eurheartj/ehv273)
Wannamethee, S. G., Welsh, P., Papacosta, O., Lennon, L., Whincup, P. H., Sattar, N. (2015) Copeptin, insulin resistance, and risk of incident diabetes in older men. Journal of Clinical Endocrinology and Metabolism, 100, pp. 3332-3339. (doi: 10.1210/JC.2015-2362)
Corcoran, D., Grant, P., Berry, C. (2015) Risk stratification in non-ST elevation acute coronary syndromes: risk scores, biomarkers and clinical judgment. International Journal of Cardiology: Heart and Vasculature, 8, pp. 131-137. (doi: 10.1016/j.ijcha.2015.06.009)
Platz, E., Jhund, P. S., Campbell, R. T., McMurray, J. (2015) Assessment and prevalence of pulmonary oedema in contemporary acute heart failure trials: a systematic review. European Journal of Heart Failure, 17, pp. 906-916. (doi: 10.1002/ejhf.321)
Fisher, M., Petrie, M., Ambery, P., Donaldson, J., McMurray, J. J.V., Ye, J. (2015) Cardiovascular safety of albiglutide in the Harmony programme: a meta-analysis. Lancet Diabetes and Endocrinology, 3, pp. 697-703. (doi: 10.1016/s2213-8587(15)00233-8)
Charytan, D. M., Lewis, E. F., Desai, A. S., Weinrauch, L. A., Ivanovich, P., Toto, R. D., Claggett, B., Liu, J., Hartley, L. H., Finn, P., Singh, A. K., Levey, A. S., Pfeffer, M. A., McMurray, J. J.V., Solomon, S. D. (2015) Cause of death in patients with diabetic CKD enrolled in the trial to reduce cardiovascular events with aranesp therapy (TREAT) American Journal of Kidney Diseases, 66, pp. 429-440. (doi: 10.1053/j.ajkd.2015.02.324)
Kao, D. P., Lewsey, J. D., Anand, I. S., Massie, B. M., Zile, M. R., Carson, P. E., McKelvie, R. S., Komajda, M., McMurray, J. J.V., Lindenfeld, J. (2015) Characterization of subgroups of heart failure patients with preserved ejection fraction with possible implications for prognosis and treatment response. European Journal of Heart Failure, 17, pp. 925-935. (doi: 10.1002/ejhf.327)
Damy, T., Hobkirk, J., Walters, M., Ciobanu, A., Rigby, A. S., Kallvikbacka-Bennett, A., Guellich, A., Dubois-Randé, J.-L., Hittinger, L., Clark, A. L., Cleland, J. G.F. (2015) Development of a human model for the study of effects of hypoxia, exercise, and sildenafil on cardiac and vascular function in chronic heart failure. Journal of Cardiovascular Pharmacology, 66, pp. 229-238. (doi: 10.1097/FJC.0000000000000262)
Dierckx, R., Cleland, J. G.F., Pellicori, P., Zhang, J., Goode, K., Putzu, P., Boyalla, V., Clark, A. L. (2015) If home telemonitoring reduces mortality in heart failure, is this just due to better guideline-based treatment? Journal of Telemedicine and Telecare, 21, pp. 331-339. (doi: 10.1177/1357633X15574947)
Mordi, I., Radjenovic, A., Stanton, T., Gardner, R., McPhaden, A., Carrick, D., Berry, C., Tzemos, N. (2015) Prevalence and prognostic significance of lipomatous metaplasia in poatients with prior myocardial infarction. JACC: Cardiovascular Imaging, 8, pp. 1111-1112. (doi: 10.1016/j.jcmg.2014.07.024)
Stut, W., Deighan, C., Cleland, J. G., Jaarsma, T. (2015) Adherence to self-care in patients with heart failure in the HeartCycle study. Patient Preference and Adherence, 9, pp. 1195-1206. (doi: 10.2147/PPA.S88482)
McMurray, J. J.V. (2015) It is BEAUTIFUL we should be concerned about, not SIGNIFY: is ivabradine less effective in ischaemic compared with non-ischaemic LVSD? European Heart Journal, 36, pp. 2047-2049. (doi: 10.1093/eurheartj/ehv190)
Desai, A. S., McMurray, J. J.V., Packer, M., Swedberg, K., Rouleau, J. L., Chen, F., Gong, J., Rizkala, A. R., Brahimi, A., Claggett, B., Finn, P. V., Hartley, L. H., Liu, J., Lefkowitz, M., Shi, V., Zile, M. R., Solomon, S. D. (2015) Effect of the angiotensin-receptor-neprilysin inhibitor LCZ696 compared with enalapril on mode of death in heart failure patients. European Heart Journal, 36, pp. 1990-1997. (doi: 10.1093/eurheartj/ehv186)
Mebazaa, A. et al. (2015) Recommendations on pre-hospital and early hospital management of acute heart failure: a consensus paper from the Heart Failure Association of the European Society of Cardiology, the European Society of Emergency Medicine and the Society of Academic Emergency Medicine – short version. European Heart Journal, 36, pp. 1958-1966. (doi: 10.1093/eurheartj/ehv066)
McComb, C., Carrick, D., McClure, J. D., Woodward, R., Radjenovic, A., Foster, J. E., Berry, C. (2015) Assessment of the relationships between myocardial contractility and infarct tissue revealed by serial magnetic resonance imaging in patients with acute myocardial infarction. International Journal of Cardiovascular Imaging, 31, pp. 1201-1209. (doi: 10.1007/s10554-015-0678-y)
Jhund, P. S., Anand, I. S., Komajda, M., Claggett, B. L., McKelvie, R. S., Zile, M. R., Carson, P. E., McMurray, J. J.V. (2015) Changes in N-terminal pro-B-type natriuretic peptide levels and outcomes in heart failure with preserved ejection fraction: an analysis of the I-Preserve study. European Journal of Heart Failure, 17, pp. 809-817. (doi: 10.1002/ejhf.274)
Jackson, C. E., Haig, C., Welsh, P., Dalzell, J. R., Tsorlalis, I. K., McConnachie, A., Preiss, D., McInnes, I. B., Sattar, N., Petrie, M. C., Gardner, R. S., McMurray, J. J.V. (2015) Combined free light chains are novel predictors of prognosis in heart failure. JACC: Heart Failure, 3, pp. 618-625. (doi: 10.1016/j.jchf.2015.03.014)
Abdalrahaman, N., Mccomb, C., Foster, J. E., McLean, J., Lindsay, R. S., McClure, J., McMillan, M., Drummond, R., Gordon, D., McKay, G. A., Shaikh, M. G., Perry, C. G., Ahmed, S. F. (2015) Deficits in trabecular bone microarchitecture in young women with Type 1 diabetes mellitus. Journal of Bone and Mineral Research, 30, pp. 1386-1393. (doi: 10.1002/jbmr.2465)
Rush, C. J., Campbell, R. T., Jhund, P. S., Connolly, E. C., Preiss, D., Gardner, R. S., Petrie, M. C., McMurray, J. J.V. (2015) Falling cardiovascular mortality in heart failure with reduced ejection fraction and implications for clinical trials. JACC: Heart Failure, 3, pp. 603-614. (doi: 10.1016/j.jchf.2015.03.013)
Yates, T., Davies, M.J., Haffner, S.M., Schulte, P.J., Thomas, L., Huffman, K.M., Bales, C.W., Preiss, D., Califf, R.M., Holman, R.R., McMurray, J.J.V., Bethel, M.A., Tuomilehto, J., Kraus, W.E. (2015) Physical activity as a determinant of fasting and 2-h post-challenge glucose: a prospective cohort analysis of the NAVIGATOR trial. Diabetic Medicine, 32, pp. 1090-1096. (doi: 10.1111/dme.12762)
Khazanie, P., Heizer, G. M., Hasselblad, V., Armstrong, P. W., Califf, R. M., Ezekowitz, J., Dickstein, K., Levy, W. C., McMurray, J. J.V., Metra, M., Wilson Tang, W.H., Teerlink, J. R., Voors, A. A., O’Connor, C. M., Hernandez, A. F., Starling, R. (2015) Predictors of clinical outcomes in acute decompensated heart failure: Acute Study of Clinical Effectiveness of Nesiritide in Decompensated heart failure outcome models. American Heart Journal, 170, pp. 290-297. (doi: 10.1016/j.ahj.2015.04.006)
Preiss, D., Thomas, L. E., Wojdyla, D. M., Haffner, S. M., Gill, J. M. R., Yates, T., Davies, M. J., Holman, R. R., McMurray, J. J., Califf, R. M., Kraus, W. E. (2015) Prospective relationships between body weight and physical activity: an observational analysis from the NAVIGATOR study. BMJ Open, 5, (doi: 10.1136/bmjopen-2015-007901)
Lewis, E. F., Claggett, B., Parfrey, P. S., Burdmann, E. A., McMurray, J. J.V., Solomon, S. D., Levey, A. S., Ivanovich, P., Eckardt, K.-U., Kewalramani, R., Toto, R., Pfeffer, M. A. (2015) Race and ethnicity influences on cardiovascular and renal events in patients with diabetes mellitus. American Heart Journal, 170, pp. 322-329.e4. (doi: 10.1016/j.ahj.2015.05.008)
Cleland, J. G.F., Mareev, Y., Linde, C. (2015) Reflections on EchoCRT: sound guidance on QRS duration and morphology for CRT? European Heart Journal, 36, pp. 1948-1951. (doi: 10.1093/eurheartj/ehv264)
Askevold, E. T., Gullestad, L., Nymo, S., Kjekshus, J., Yndestad, A., Latini, R., Cleland, J. G.F., McMurray, J. J.V., Aukrust, P., Ueland, T. (2015) Secreted frizzled related protein 3 in chronic heart failure: analysis from the controlled rosuvastatin multinational trial in heart failure (CORONA) PLoS ONE, 10, (doi: 10.1371/journal.pone.0133970)
Garg, S., Anderson, S.G., Oldroyd, K., Berry, C., Emdin, C.A., Peters, S.A.E., West, N.E.J., Kelly, D., Balachandran, K., McDonald, J., Singh, R., Devadathan, S., Redwood, S., Ludman, P.F., Rahimi, K., Woodward, M. (2015) Outcomes of percutaneous coronary intervention performed at offsite versus onsite surgical centers in the United Kingdom. Journal of the American College of Cardiology, 66, pp. 363-372. (doi: 10.1016/j.jacc.2015.05.052)
Raphael, C. E., Finegold, J. A., Barron, A. J., Whinnett, Z. I., Mayet, J., Linde, C., Cleland, J. G.F., Levy, W. C., Francis, D. P. (2015) The effect of duration of follow-up and presence of competing risk on lifespan-gain from implantable cardioverter defibrillator therapy: who benefits the most? European Heart Journal, 36, pp. 1676-1688. (doi: 10.1093/eurheartj/ehv102)
Emdin, C. A., Callender, T., Cao, J., McMurray, J. J.V., Rahimi, K. (2015) Meta-analysis of large-scale randomized trials to determine the effectiveness of inhibition of the renin-angiotensin aldosterone system in heart failure. American Journal of Cardiology, 116, pp. 155-61. (doi: 10.1016/j.amjcard.2015.03.052)
MacDonald, M. R., She, L., Doenst, T., Binkley, P. F., Rouleau, J. L., Tan, R.-S., Lee, K. L., Miller, A. B., Sopko, G., Szalewska, D., Waclawiw, M. A., Dabrowski, R., Castelvecchio, S., Adlbrecht, C., Michler, R. E., Oh, J. K., Velazquez, E. J., Petrie, M. C. (2015) Clinical characteristics and outcomes of patients with and without diabetes in the Surgical Treatment for Ischemic Heart Failure (STICH) trial. European Journal of Heart Failure, 17, pp. 725-734. (doi: 10.1002/ejhf.288)
Cannon, J.A., Collier, T.J., Shen, L., Swedberg, K., Krum, H., Van Veldhuisen, D.J., Vincent, J., Pocock, S.J., Pitt, B., Zannad, F., McMurray, J.J.V. (2015) Clinical outcomes according to QRS duration and morphology in the eplerenone in mild patients: hospitalization and survIval study in heart failure (EMPHASIS-HF) European Journal of Heart Failure, 17, pp. 707-716. (doi: 10.1002/ejhf.303)
Mentz, R. J., Metra, M., Cotter, G., Milo, O., McKendry, C., Chiswell, K., Davison, B. A., Cleland, J. G.F., Bloomfield, D. M., Dittrich, H. C., Fiuzat, M., Ponikowski, P., Givertz, M. M., Voors, A. A., Teerlink, J. R., O'Connor, C. M. (2015) Early vs. late worsening heart failure during acute heart failure hospitalization: insights from the PROTECT trial. European Journal of Heart Failure, 17, pp. 697-706. (doi: 10.1002/ejhf.308)
Green, J. B., Bethel, M. A., Armstrong, P. W., Buse, J. B., Engel, S. S., Garg, J., Josse, R., Kaufman, K. D., Koglin, J., Korn, S., Lachin, J. M., McGuire, D. K., Pencina, M. J., Standl, E., Stein, P. P., Suryawanshi, S., Van de Werf, F., Peterson, E. D., Holman, R. R., McMurray, J. (2015) Effect of sitagliptin on cardiovascular outcomes in type 2 diabetes. New England Journal of Medicine, 373, pp. 232-242. (doi: 10.1056/NEJMoa1501352)
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Ripley, D. P., Brown, J., Everett, C. C., Bijsterveld, P., Walker, S., Sculpher, M., McCann, G. P., Berry, C., Plein, S., Greenwood, J. P. (2015) Rationale and design of the Clinical Evaluation of Magnetic Resonance Imaging in Coronary heart disease 2 trial (CE-MARC 2): a prospective, multicenter, randomized trial of diagnostic strategies in suspected coronary heart disease. American Heart Journal, 169, pp. 17-24.e1. (doi: 10.1016/j.ahj.2014.10.008)
Dierckx, R., Pellicori, P., Cleland, J.G.F., Clark, A.L. (2015) Telemonitoring in heart failure: Big Brother watching over you. Heart Failure Reviews, 20, pp. 107-116. (doi: 10.1007/s10741-014-9449-4)
Abualnaja, S., Podder, M., Hernandez, A. F., McMurray, J. J. V., Starling, R. C., O'Connor, C. M., Califf, R. M., Armstrong, P. W., Ezekowitz, J. A. (2015) Acute heart failure and atrial fibrillation: insights from the acute study of clinical effectiveness of nesiritide in decompensated heart failure (ASCEND‐HF) trial. Journal of the American Heart Association, 4, (doi: 10.1161/JAHA.115.002092)
Layland, J., Rauhalammi, S., Watkins, S., Ahmed, N., McClure, J., Lee, M. M.Y., Carrick, D., O’Donnell, A., Sood, A., Petrie, M. C., Teng Yue May, V., Eteiba, H., Lindsay, M., McEntegart, M., Oldroyd, K. G., Radjenovic, A., Berry, C. (2015) Assessment of fractional flow reserve in patients with recent Non–ST-Segment–Elevation Myocardial Infarction. Circulation: Cardiovascular Interventions, 8, (doi: 10.1161/circinterventions.114.002207)
Welsh, P., Preiss, D., Touyz, R. M. (2015) Biomarkers of hypertension and cardiovascular disease. Royal Society of Chemistry
Welsh, P., Preiss, D., Tsiropoulou, S., Rios, F. J., Harvey, A., Dulak-Lis, M. G., Montezano, A. C., Touyz, R. M. (2015) Biomarkers of vascular inflammation and cardiovascular disease. Springer
Newby, D. et al. (2015) CT coronary angiography in patients with suspected angina due to coronary heart disease (SCOT-HEART): an open-label, parallel-group, multicentre trial. Lancet, 385, pp. 2383-2391. (doi: 10.1016/S0140-6736(15)60291-4)
Badar, A. A., Perez-Moreno, A. C., Hawkins, N. M., Jhund, P. S., Brunton, A. P.T., Anand, I. S., McKelvie, R. S., Komajda, M., Zile, M. R., Carson, P. E., Gardner, R. S., Petrie, M. C., McMurray, J. J.V. (2015) Clinical characteristics and outcomes of patients with coronary artery disease and angina. Circulation: Heart Failure, 8, pp. 717-724. (doi: 10.1161/CIRCHEARTFAILURE.114.002024)
Corcoran, D., Berry, C., Oldroyd, K. (2015) Current frontiers in the clinical research of coronary physiology. Interventional Cardiology, 7, pp. 97-106.
Campbell, R. T., Jhund, P. S., Dalzell, J. R., Cannon, J., Mordi, I., Sonecki, P., Tzemos, N. (2015) Diagnosis and resolution of loeffler endocarditis secondary to eosinphilic granulomatosis with polyangiitis demonstrated by cardiac magnetic resonance-t2 mapping. Circulation, 131, pp. 114-117. (doi: 10.1161/CIRCULATIONAHA.114.011291)
Jackson, C. E., Castagno, D., Maggioni, A. P., Køber, L., Squire, I. B., Swedberg, K., Andersson, B., Richards, A. M., Bayes-Genis, A., Tribouilloy, C., Dobson, J., Ariti, C. A., Poppe, K. K., Earle, N., Whalley, G., Pocock, S. J., Doughty, R. N., McMurray, J. J.V. (2015) Differing prognostic value of pulse pressure in patients with heart failure with reduced or preserved ejection fraction: results from the MAGGIC individual patient meta-analysis. European Heart Journal, 36, pp. 1106-14. (doi: 10.1093/eurheartj/ehu490)
McMurray, J. (2015) Ethnic-specific normative reference values for echocardiographic LA and LV size, LV mass, and systolic function: the EchoNoRMAL Study. JACC: Cardiovascular Imaging, 8, pp. 656-665. (doi: 10.1016/j.jcmg.2015.02.014)
Gao, H., Qi, N., Ma, X., Griffith, B. E., Berry, C., Luo, X. (2015) Fluid-structure interaction model of human mitral valve within left ventricle. Springer International Publishing
Lopez, L. M., Hill, W. D., Harris, S. E., Valdes Hernandez, M., Munoz Maniega, S., Bastin, M. E., Bailey, E., Smith, C., McBride, M., McClure, J., Graham, D., Dominiczak, A., Yang, Q., Fornage, M., Ikram, M. A., Debette, S., Launer, L., Bis, J. C., Schmidt, R., Seshadri, S., Porteous, D. J., Starr, J., Deary, I. J., Wardlaw, J. M. (2015) Genes from a translational analysis support a multifactorial nature of white matter hyperintensities. Stroke, 46, pp. 341-347. (doi: 10.1161/STROKEAHA.114.007649)
Jhund, P. S. (2015) Heart failure management: continuing to fail or signs of success? Cardiovascular Drugs and Therapy, 29, pp. 5-6. (doi: 10.1007/s10557-015-6574-9)
Gao, H., Berry, C., Luo, X. (2015) Image-derived human left ventricular modelling with fluid-structure interaction. Springer International Publishing
Aitken, E., Geddes, C., Thomson, P., Kasthuri, R., Chandramohan, M., Berry, C., Kingsmore, D. (2015) Immediate access arteriovenous grafts versus tunnelled central venous catheters: study protocol for a randomised controlled trial. Trials, 16, (doi: 10.1186/s13063-015-0556-x)
Dalzell, J. R., Cannon, J. A., Simpson, J., Gardner, R. S., Petrie, M. C. (2015) Improving outcomes in peripartum cardiomyopathy. Expert Review of Cardiovascular Therapy, 13, pp. 665-671. (doi: 10.1586/14779072.2015.1040767)
Mangion, K., Carrick, D., Payne, A., McClure, J., Mason, M., Petrie, M., McEntegart, M., Eteiba, H., Oldroyd, K., Berry, C. (2015) Infarct burden following multivessel PCI vs. infarct-only PCI in patients with acute STEMI: the Glasgow PRAMI CMR sub-study. Journal of Cardiovascular Magnetic Resonance, 17, (doi: 10.1186/1532-429X-17-S1-O9)
Souteyrand, G., Amabile, N., Combaret, N., Hammas, S., Prati, F., Berry, C., Pereira, B., Lusson, J.-R., Caussin, C., Motreff, P. (2015) Invasive management without stents in selected acute coronary syndrome patients with a large thrombus burden: a prospective study of optical coherence tomography guided treatment decisions. EuroIntervention, 11, pp. 895-904. (doi: 10.4244/eijy14m07_18)
Hennigan, B., Robertson, K., Berry, C., Oldroyd, K. G. (2015) Is hyperaemia essential for accurate functional assessment of coronary stenosis severity? Interventional Cardiology Review, 10, pp. 72-78. (doi: 10.15420/icr.2015.10.2.72)
Mangion, K., Carrick, D., Payne, A. R., McClure, J., Mason, M., Petrie, M., McEntegart, M., Eteiba, H., Oldroyd, K. G., Berry, C. (2015) Left ventricular outcomes following multivessel PCI vs. infarct artery-only PCI in patients with acute STEMI: the Glasgow PRAMI CMR sub-study. Journal of Cardiovascular Magnetic Resonance, 17, (doi: 10.1186/1532-429X-17-S1-P104)
MacCannell, K.A., Chilton, L., Smith, G.L., Giles, W.R. (2015) Mathematical simulations of sphingosine-1-phosphate actions on mammalian ventricular myofibroblasts and myocytes. Springer
McMurray, J., Zhu, L., McKillop, I., Chen, H. (2015) Modelling system level health information exchange: an ontological approach. Studies in Health Technology and Informatics, 208, pp. 269-274.
McMurray, J. J.V. (2015) Neprilysin inhibition to treat heart failure: a tale of science, serendipity, and second chances. European Journal of Heart Failure, 17, pp. 242-7. (doi: 10.1002/ejhf.250)
Carrick, D., Haig, C., Rauhalammi, S., Ahmed, N., Mordi, I., McEntegart, M., Petrie, M., Eteiba, H., Hood, S., Watkins, S., Lindsay, M., Marous, A., Radjenovic, A., Ford, I., Tzemos, N., Oldroyd, K., Berry, C. (2015) Pathophysiology of myocardial remodeling in survivors of ST-elevation myocardial infarction revealed by native T1 mapping: inflammation, remote myocardium and prognostic significance. Journal of Cardiovascular Magnetic Resonance, 17, (doi: 10.1186/1532-429X-17-S1-Q52)
Robertson, K. E., Hennigan, B., Berry, C., Oldroyd, K. G. (2015) Physiological assessment of coronary lesion severity. Coronary Artery Disease, 26, pp. e8-e14. (doi: 10.1097/MCA.0000000000000212)
Carrick, D., Haig, C., Rauhalammi, S. M., Ahmed, N., Mordi, I., McEntegart, M., Petrie, M., Eteiba, H., Hood, S., Watkins, S., Lindsay, M., Marous, A., Radjenovic, A., Ford, I., Tzemos, N., Oldroyd, K. G., Berry, C. (2015) Prognostic significance of infarct core pathology in ST-elevation myocardial infarction survivors revealed by non-contrast T1 mapping cardiac magnetic resonance. Journal of Cardiovascular Magnetic Resonance, 17, (doi: 10.1186/1532-429X-17-S1-O26)
Carrick, D., Haig, C., Rauhalammi, S., Ahmed, N., Mordi, I., McEntegart, M., Petrie, M., Eteiba, H., Hood, S., Watkins, S., Lindsay, M., Marous, A., Radjenovic, A., Ford, I., Tzemos, N., Oldroyd, K., Berry, C. (2015) Prognostic significance of infarct core pathology in ST-elevation myocardial infarction survivors revealed by quantitative T2-weighted cardiac magnetic resonance. Journal of Cardiovascular Magnetic Resonance, 17, (doi: 10.1186/1532-429X-17-S1-O54)
Carrick, D., Haig, C., Rauhalammi, S., Ahmed, N., Mordi, I., McEntegart, M., Petrie, M., Eteiba, H., Hood, S., Watkins, S., Lindsay, M., Marous, A., Radjenovic, A., Ford, I., Tzemos, N., Oldroyd, K., Berry, C. (2015) Prognostic significance of quantitative measures of myocardial infarct pathology using native T1 mapping, in survivors of ST-elevation myocardial infarction. Journal of Cardiovascular Magnetic Resonance, 17, pp. O53. (doi: 10.1186/1532-429X-17-S1-O53)
Voors, A. A., Gori, M., Liu, L. C.Y., Claggett, B., Zile, M. R., Pieske, B., McMurray, J. J.V., Packer, M., Shi, V., Lefkowitz, M. P., Solomon, S. D. (2015) Renal effects of the angiotensin receptor neprilysin inhibitor LCZ696 in patients with heart failure and preserved ejection fraction. European Journal of Heart Failure, 17, pp. 510-517. (doi: 10.1002/ejhf.232)
Abdul-Rahim, A. H., Perez, A.-C., Fulton, R. L., Jhund, P. S., Latini, R., Tognoni, G., Wikstrand, J., Kjekshus, J., Lip, G. Y.H., Maggioni, A. P., Tavazzi, L., Lees, K. R., McMurray, J. J.V. (2015) Response to Letter Regarding Article, “Risk of Stroke in Chronic Heart Failure Patients Without Atrial Fibrillation: Analysis of the Controlled Rosuvastatin in Multinational Trial Heart Failure (CORONA) and the Gruppo Italiano per lo Studio della Sopravvivenza nell’Insufficienza Cardiaca-Heart Failure (GISSI-HF) Trials.” Circulation, 132, (doi: 10.1161/CIRCULATIONAHA.115.018395)
Lam, C. S. P., McEntegart, M., Claggett, B., Liu, J., Skali, H., Lewis, E., Køber, L., Rouleau, J., Velazquez, E., Califf, R., McMurray, J. J.V., Pfeffer, M., Solomon, S. (2015) Sex differences in clinical characteristics and outcomes after myocardial infarction: insights from the valsartan in acute myocardial infarction trial (VALIANT) European Journal of Heart Failure, 17, pp. 301-312. (doi: 10.1002/ejhf.238)
Kwok, C. S., Kontopantelis, E., Myint, P. K., Zaman, A., Berry, C., Keavney, B., Nolan, J., Ludman, P. F., de Belder, M. A., Buchan, I., Mamas, M. A. (2015) Stroke following percutaneous coronary intervention: type-specific incidence, outcomes and determinants seen by the British Cardiovascular Intervention Society 2007–12. European Heart Journal, 36, pp. 1618-1628. (doi: 10.1093/eurheartj/ehv113)
Lewsey, J., Ebueku, O., Jhund, P. S., Gillies, M., Chalmers, J. W.T., Redpath, A., Briggs, A., Walters, M., Langhorne, P., Capewell, S., McMurray, J. J.V., MacIntyre, K. (2015) Temporal trends and risk factors for readmission for infections, gastrointestinal and immobility complications after an incident hospitalisation for stroke in Scotland between 1997 and 2005. BMC Neurology, 15, (doi: 10.1186/s12883-014-0257-1)
Roberts, E., Ludman, A. J., Dworzynski, K., Al-Mohammad, A., Cowie, M. R., McMurray, J. J. V., Mant, J. (2015) The diagnostic accuracy of the natriuretic peptides in heart failure: systematic review and diagnostic meta-analysis in the acute care setting. British Medical Journal, 350, (doi: 10.1136/bmj.h910)
Carson, P. E., Anand, I. S., Win, S., Rector, T., Haass, M., Lopez-Sendon, J., Miller, A., Teerlink, J. R., White, M., McKelvie, R. S., Komajda, M., Zile, M. R., McMurray, J. J., Massie, B. (2015) The hospitalization burden and post-hospitalization mortality risk in heart failure with preserved ejection fraction: results from the I-PRESERVE Trial (Irbesartan in Heart Failure and Preserved Ejection Fraction) JACC: Heart Failure, 3, pp. 429-441. (doi: 10.1016/j.jchf.2014.12.017)
Sattar, N., Welsh, P., Preiss, D. (2015) The insulin resistance syndrome. John Wiley & Sons, Ltd
Badar, A. A., Brunton, A. P.T., Mahmood, A. H., Dobbin, S., Pozzi, A., McMinn, J. F., Sinclair, A. J.E., Gardner, R. S., Petrie, M. C., Curry, P. A., Al-Attar, N. H.K., Pettit, S. J. (2015) The management of patients with aortic regurgitation and severe left ventricular dysfunction: a systematic review. Expert Review of Cardiovascular Therapy, 13, pp. 915-922. (doi: 10.1586/14779072.2015.1067139)
Cannon, J. A., McMurray, J. J.V., Quinn, T. J. (2015) ‘Hearts and minds’: association, causation and implication of cognitive impairment in heart failure. Alzheimer's Research and Therapy, 7, (doi: 10.1186/s13195-015-0106-5)
PGR Students
- Postgraduate Research Student
- Research title: Developing Therapeutic Approaches for Hemorrhagic Stroke
- Postgraduate Research Student
- Research title: Investigating the mechanisms of acute preservation of cardiac function post-MI following angiotensin-(1-9) gene therapy
Our academic unit is integral to the School of Cardiovascular and Metabolic Health within the University of Glasgow and the National Health Service. The unit is led by Colin Berry, Professor of Cardiology and Imaging supported by Richard Good, Senior Clinical Lecturer and Consultant Interventional Cardiologist, and a team of post-doctoral and doctoral researchers. We prioritize careers development and diversity within our teams. Our clinical research is conducted in collaboration with clinical and academic colleagues in NHS Greater Glasgow and Clyde, NHS Lanarkshire and the Golden Jubilee National Hospital. Together these health boards provide care for a population of 2.5 million people and the NHS Golden Jubilee also provides national services for advanced heart failure and transplantation, adult congenital heart disease and pulmonary vascular disease. Beyond the west of Scotland, we lead and support national and international collaborations to deliver impactful research and innovation in ischaemic heart disease.
We have advanced the agenda for a more inclusive approach to research and healthcare in ischaemic heart disease. Coronary heart disease (CHD), ischaemia with no obstructive arteries (INOCA) and myocardial infarction with no obstructive coronary arteries (MINOCA) and distinct conditions that may cause angina, myocardial infarction, arrhythmias, heart failure and systemic health problems, including vascular dementia. We prioritise research relevant to underserved groups, notably heart disease in women, and persons living with socio-economic deprivation. Our research has led to changes in clinical practice guidelines of the European Society of Cardiology and North American societies and had a direct impact on society, for example the Women’s Health Plan of the Scottish Government policy reports issued by the British Heart Foundation such as Bias and Biology (2019) and Igniting Change (2022).
We investigate complex problems through an interdisciplinary, population-bedside-bench approach. We target unanswered health problems through clinical trials and cohort studies. We implement deep clinical phenotyping involving noninvasive and invasive methods (biochemistry, imaging, physiology, biostatistics) and collect tissue (blood, biopsies (cells, arteries)) enabling laboratory-based cardiovascular science and collaborations with biomedical and fundamental scientists. To direct impact on clinical practice, population health and health policies, we collaborate with the Health Economics and Health Technology Assessment (HEHTA) research group and the Robertson Centre for Biostatistics/Clinical Trials Unit in the University of Glasgow. We are privileged to collaborate with commercial partners.
Clinical expertise
- coronary angiography and physiology testing
- intravascular coronary imaging
- percutaneous coronary intervention (PCI) and coronary artery bypass surgery (CABG)
- cardiovascular magnetic resonance imaging (CMR)
- computed tomography coronary angiography (CCTA)
Biomedical expertise
- Biomarkers
- Vascular science - physiology and pharmacology; genomics, cell culture, signalling and transcriptomics.
Our group has a track-record of peer-reviewed research awards. We have led major awards from the British Heart Foundation (Centre of Research Excellence, Programme Grants), Engineering and Physical Sciences Research Council and Medical Research Council of UKRI, the European Commission and industry. Careers development is central to our work, and we prioritise support for early career researchers within the Graduate Schools of the College of Medicine, Veterinary Medicine and Life Sciences (MVLS) and the College of Science and Engineering at the University of Glasgow.
Our group actively contributes to national and international forums. We also have leadership roles in international forums including COVADIS (Coronary Vasomotor Disorders International Study Group) and the European Society of Cardiology. We support the British Cardiovascular Society (BCS), the British Society of Cardiovascular Magnetic Resonance (BSCMR), the British Cardiovascular Intervention Society (BCIS) and the British Society for Cardiovascular Research (BSCR). We have the privilege of contributing to patient forums including INOCA International and the International Heart Spasms Alliance.
Current and recent clinical trials:
- CorMicA – Stratified Medical Therapy Using Invasive Coronary Function Testing in Angina: The CorMicA Trial. https://www.jacc.org/doi/abs/10.1016/j.jacc.2018.09.006
- iCorMicA – an international clinical trial of stratified management of angina. https://clinicaltrials.gov/study/NCT04674449
- CorCTA - Invasive Endotyping in Patients With Angina and No Obstructive Coronary Artery Disease: A Randomized Controlled Trial; published in Circulation (2024) as a Featured Research Article: https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.123.064751
- CorCMR – a multicentre trial of stress perfusion MRI-guided management in patients with angina and no obstructive coronary artery disease. https://clinicaltrials.gov/study/NCT04805814
- StratMed-MINOCA – a multicentre trial of stratified therapy using eplerenone in myocardial infarction and no obstructive coronary artery disease (MINOCA): https://clinicaltrials.gov/study/NCT05198791
- Precision Medicine With Zibotentan in Microvascular Angina (PRIZE) – a multicentre clinical trial. https://clinicaltrials.gov/study/NCT04097314
- CT Coronary Angiography for Type 2 Myocardial Infarction: a pilot clinical trial. https://classic.clinicaltrials.gov/ct2/show/NCT06047392
- CISCO-21 - Prevention and Early Treatment of the Long-term Physical Effects of Coronarvirus-19 (COVID-19): a Randomised Clinical Trial of Resistance Exercise. https://clinicaltrials.gov/study/NCT04900961
- PROTECT Gene therapy for prevent coronary artery bypass graft vein graft failure
Key collaborations
- Laboratory based research assessing the mechanisms responsible for IHD to explore new therapeutic targets
- http://www.softmech.org/ - a collaboration with academic colleagues in engineering, mathematics and computing science to deliver groundbreaking modelling of cardiac disease and therapeutic interventions
- Application of artificial intelligence to imaging to improve the diagnosis and management of IHD