Heart Failure
We aim to improve outcomes for patients with heart failure through improving understanding of the clinical syndrome of heart failure and developing the evidence-base for heart failure therapies.
Staff
Publications
2024
De Biase, N., Del Punta, L., L'Hoyes, W., Pellicori, P., Cleland, J. G.F., Masini, G., Gargani, L., Moura-Ferreira, S., Hoedemakers, S., Di Fiore, V., Herbots, L., Stassen, J., Mengozzi, A., Armenia, S., Taddei, S., Masi, S., Verwerft, J., Pugliese, N. R. (2024) Associations of iron deficiency with cardiac function, congestion, exercise capacity and prognosis in heart failure. European Journal of Heart Failure,
Osmanska, J., Petrie, M. C., Docherty, K. F., Lee, M. M.Y., McMurray, J. J.V., Campbell, R. (2024) Subcutaneous furosemide in heart failure: a systematic review. European Heart Journal: Cardiovascular Pharmacotherapy, (doi: 10.1093/ehjcvp/pvae083)
Averbuch, T., Lee, S. F., Zagorski, B., Pandey, A., Petrie, M. C., Biering‐Sorensen, T., Xie, F., Van Spall, H. G.C. (2024) Long‐term clinical outcomes and healthcare resource utilization in male and female patients following hospitalization for heart failure. European Journal of Heart Failure, (doi: 10.1002/ejhf.3499)
Naeem, F., Penfold, R. S., Soiza, R. L., Von Haken, R., Lindroth, H., Liu, K., Nydhal, P., Quinn, T. J. (2024) Delirium assessment, management and barriers to effective care across Scotland: a secondary analysis of survey data from World Delirium Awareness Day 2023. Journal of the Royal College of Physicians of Edinburgh,
Zervou, S., McAndrew, D. J., Lake, H. A., Kuznecova, E., Preece, C., Davies, B., Neubauer, S., Lygate, C. A. (2024) Cardiac function and energetics in mice with combined genetic augmentation of creatine and creatine kinase activity. Journal of Molecular and Cellular Cardiology, 196, pp. 105-114. (doi: 10.1016/j.yjmcc.2024.09.007)
Main, A., Mary, S., Sin, Y. Y., Wright, T. A., Ling, J., Blair, C. M., Smith, G. L., Fuller, W., Baillie, G. S. (2024) SUMOylation of cardiac myosin binding protein-C reduces its phosphorylation and results in impaired relaxation following treatment with isoprenaline. International Journal of Biochemistry and Cell Biology, 176, (doi: 10.1016/j.biocel.2024.106668)
Rochmawati, I. D., Deo, S., Lees, J. S., Mark, P. B., Sattar, N., Celis-Morales, C., Pell, J. P., Welsh, P., Ho, F. K. (2024) Adding traditional and emerging biomarkers for risk assessment in secondary prevention: a prospective cohort study of 20,656 patients with cardiovascular disease. European Journal of Preventive Cardiology, (doi: 10.1093/eurjpc/zwae352)
Tvrdá, L., Mavromati, K., Taylor-Rowan, M., Quinn, T. J. (2024) Comparing the properties of traditional and novel approaches to the Modified Rankin Scale: systematic review and meta-analysis. European Stroke Journal, (doi: 10.1177/23969873241293569)
Xiong, X., Lui, D. T.W., Ju, C., Zhou, Z., Xu, C., Welsh, P., Sattar, N., Celis-Morales, C., Pell, J. P., Wong, I. C.K., Wong, C. K.H., Ho, F. (2024) Associations of serum lipid traits with fracture and osteoporosis: a prospective cohort study from the UK Biobank. Journal of Cachexia, Sarcopenia and Muscle, (doi: 10.1002/jcsm.13611)
Dieden, A., Girerd, N., Ottosson, F., Molvin, J., Pareek, M., Melander, O., Bachus, E., Råstam, L., Lindblad, U., Daka, B., Leósdóttir, M., Nilsson, P. M., Olsen, M. H., Clark, A. L., Cleland, J. G.F., Delles, C., González, A., Lamiral, Z., Duarte, K., Rossignol, P., Zannad, F., Gudmundsson, P., Jujić, A., Magnusson, M. (2024) Proteomic biomarkers and pathway analysis for progression to heart failure in three epidemiological representative cohorts. European Journal of Heart Failure, (doi: 10.1002/ejhf.3502)
Foley, P.W., Kalra, P.R., Cleland, J.G.F., Petrie, M.C., Kalra, P.A., Squire, I., Campbell, P., Chapman, C., Donnelly, P., Graham, F., Hannah, A., Lang, N.N., Matthews, I., Leslie, S.J., Pellicori, P., Piper, S., Ray, R., Savage, H.O., Spencer, C., Walsh, J., Wong, Y., Ford, I. (2024) Effect of correcting iron deficiency on the risk of serious infection in heart failure insights from the IRONMAN trial. European Journal of Heart Failure, (doi: 10.1002/ejhf.3504)
Pontiroli, A. E., Tagliabue, E., Madotto, F., Leoni, O., Antonelli, B., Carluccio, E., Bandera, F., Galati, G., Pellicori, P., Lund, L. H., Ambrosio, G. (2024) Association of non-cardiac comorbidities and sex with long-term re-hospitalization for heart failure. European Journal of Internal Medicine,
Kancheva, A. K., Lyall, D. M., Millard, L., Wardlaw, J. M., Quinn, T. J. (2024) Clinical phenotypes associated with cerebral small vessel disease: a study of 45,013 UK biobank participants. Neurology, 103, (doi: 10.1212/WNL.0000000000209919)
Lu, H., Claggett, B. L., Packer, M., Pfeffer, M. A., Swedberg, K., Rouleau, J., Zile, M. R., Lefkowitz, M., Desai, A. S., Jhund, P. S., McMurray, J. J.V., Solomon, S. D., Vaduganathan, M. (2024) Visit‐to‐visit changes in heart rate in heart failure: A pooled participant‐level analysis of the PARADIGM‐HF and PARAGON‐HF trials. European Journal of Heart Failure, (doi: 10.1002/ejhf.3487)
Andonovic, M., Morrison, H., Allingham, W., Adam, R., Shaw, M., Quasim, T., McPeake, J., Quinn, T. (2024) Mechanisms underlying neurocognitive dysfunction following critical illness: a systematic review. Anaesthesia,
Costello, R. E. et al. (2024) Impacts of the COVID-19 pandemic on deprivation-level differences in cardiovascular hospitalisations: a comparison of England and Denmark using the OpenSAFELY platform and National Registry Data. BMJ Open, 14, (doi: 10.1136/bmjopen-2024-088710)
Docherty, K. F., Buendia Lopez, R., Folkvaljon, F., de Boer, R. A., Chen, J., Hammarstedt, A., Kitzman, D. W., Kosiborod, M. N., Langkilde, A. M., Reicher, B., Senni, M., Wilderäng, U., Verma, S., Cowie, M. R., Solomon, S. D., McMurray, J. (2024) Wearable accelerometer-derived measures of physical activity in heart failure: insights from the DETERMINE trials. Journal of Cardiac Failure,
MacRae, J., Ciminata, G., Geue, C., Lynch, E., Shenkin, S. D., Quinn, T. J., Burton, J. K. (2024) Mortality among long-term care residents: a retrospective cohort study. BMJ Supportive and Palliative Care, (doi: 10.1136/spcare-2024-005163)
Varga, C. R., Cleland, J. G.F., Abraham, W. T., Lip, G. Y.H., Leyva, F., Hatamizadeh, P. (2024) Implantable cardioverter defibrillator and resynchronization therapy in patients with overt chronic kidney disease. Journal of the American College of Cardiology, 84, pp. 1342-1362. (doi: 10.1016/j.jacc.2024.05.081)
Ho, F., Allan, M., Shao, H., Man, K. K.C., Jani, B. D., Lyall, D., Hastie, C., Fleming, M., Mackay, D., Cleland, J. G.F., Delles, C., Dundas, R., Lewsey, J., Ip, P., Wong, I., Welsh, P., Pearce, A., Wright, C. M., Minnis, H., Katikireddi, V., Pell, J. P. (2024) Maternal and pregnancy factors contributing to the association between area deprivation and infant mortality in England: a retrospective cohort study. Lancet Regional Health - Europe, (doi: 10.1016/j.lanepe.2024.101075)
Lee, M., Petrie, M. C., Cleland, J. G.F., Donnelly, P., Francis, M., Hannah, A., Japp, A. G., Labinjoh, C., Lang, N. N., Mainsty, C., Petrie, C. J., Piper, S. E., Williams, S. G., Ford, I., Kalra, P. R., IRONMAN Trial Investigators, (2024) Administration of ferric derisomaltose for iron deficiency and heart failure during hospital admission or at the clinic – insights from the IRONMAN trial. European Journal of Heart Failure, 26, pp. 2293-2295. (doi: 10.1002/ejhf.3394)
Liu, Q., Celis-Morales, C., Lees, J. S., Sattar, N., Ho, F., Pell, J. P., Mark, P. B., Welsh, P. (2024) Change in physical activity and its association with decline in kidney function: A UK Biobank-based cohort study. Journal of Cachexia, Sarcopenia and Muscle, 15, pp. 2046-2055. (doi: 10.1002/jcsm.13551)
Docherty, K. F., Lopez, R. B., Folkvaljon, F., de Boer, R. A., Cowie, M. R., Hammarstedt, A., Kitzman, D. W., Kosiborod, M. N., Langkilde, A. M., Reicher, B., Senni, M., Shah, S. J., Verma, S., Solomon, S. D., McMurray, J. J.V. (2024) Effect of dapagliflozin on accelerometer-based measures of physical activity in patients with heart failure: an analysis of the DETERMINE trials. Circulation: Heart Failure, 17, (doi: 10.1161/CIRCHEARTFAILURE.124.012349)
Cleland, J. G.F. (2024) Home-time is good, but feeling well is better: patient-journey and quality-home-time as endpoints in heart failure trials and registries. Circulation: Heart Failure, 17, (doi: 10.1161/CIRCHEARTFAILURE.124.012263)
Abdin, A., Jhund, P. S. (2024) Implementation of guideline‐directed medical therapy for heart failure: Progress achieved, work ahead! European Journal of Heart Failure, 26, pp. 2258-2260. (doi: 10.1002/ejhf.3438)
Sliwa, K., Rakisheva, A., Viljoen, C., Pfeffer, T., Simpson, M., Jackson, A. M., Petrie, M. C., van der Meer, P., Al Farhan, H., Jovanova, S., Mbakwem, A., Sinagra, G., Van Craenenbroeck, E., Hoevelmann, J., Johnson, M. R., Mindham, R., Chioncel, O., Kahl, K. G., Rosano, G., Tschöpe, C., Mebazaa, A., Seferovic, P., Bauersachs, J. (2024) Living with peripartum cardiomyopathy: A statement from the Heart Failure Association and the Association of Cardiovascular Nursing and Allied Professions of the European Society of Cardiology. European Journal of Heart Failure, 26, pp. 2143-2154. (doi: 10.1002/ejhf.3377)
Pellicori, P., Cuthbert, J. J., Clark, A. L., Cleland, J. G.F. (2024) Managing water and salt balance in heart failure: Is there anything else to consider other than diet and diuretics? European Journal of Heart Failure, 26, pp. 2140-2142. (doi: 10.1002/ejhf.3374)
Keene, D. et al. (2024) Predictors of the efficacy of His bundle pacing in patients with a prolonged PR interval: A stratified analysis of the HOPE‐HF randomized controlled trial. European Journal of Heart Failure, 26, pp. 2261-2268. (doi: 10.1002/ejhf.3367)
Chatur, S., Beldhuis, I. E., Claggett, B. L., McCausland, F. R., Neuen, B. L., Desai, A. S., Rouleau, J. L., Zile, M. R., Packer, M., Pfeffer, M. A., Lefkowitz, M. P., McMurray, J. J.V., Solomon, S. D., Vaduganathan, M. (2024) Sacubitril/valsartan in patients with heart failure and deterioration in eGFR to <30 mL/min/1.73 m2. JACC: Heart Failure, 12, pp. 1692-1703. (doi: 10.1016/j.jchf.2024.03.014)
Yu, Y.-L. et al. (2024) Urinary proteomic signature of mineralocorticoid receptor antagonism by spironolactone: evidence from the HOMAGE trial. Heart, 110, pp. 1180-1187. (doi: 10.1136/heartjnl-2023-323796)
Binning, L., Basquill, C., Tvrdá, L., Quinn, T. (2024) Epidemiology and outcomes associated with cognitive frailty and reserve in a stroke population: systematic review and meta-analysis. Cerebrovascular Diseases, pp. 1–21. (doi: 10.1159/000541670)
Cheng, L., Hammersley, D., Ragavan, A., Javed, S., Mukhopadhyay, S., Gregson, J., Han, J., Khalique, Z., Lota, A., Pantazis, A., Baksi, A. J., Carr‐White, G., de Marvao, A., Ware, J., Tayal, U., Pennell, D. J., Cleland, J. G.F., Prasad, S. K., Halliday, B. P. (2024) Long‐term follow‐up of the TRED ‐ HF trial: Implications for therapy in patients with dilated cardiomyopathy and heart failure remission. European Journal of Heart Failure, (doi: 10.1002/ejhf.3475)
Knight, K., Finnegan, N., Rafter, A., Forbes, D., Black, D., Quinn, T. (2024) The feasibility and validity of sarcopenia assessment using standard of care stroke imaging. Cerebrovascular Diseases, (doi: 10.1159/000541649)
Wang, X., Pabon, M. A., Cikes, M., Jering, K., Mullens, W., Kober, L., Jhund, P. S., Kovacs, A., Merkely, B., Zhou, Y., McMurray, J. J.V., Shah, A. M., Hegde, S. M., Claggett, B., Pfeffer, M. A., Solomon, S. D. (2024) Sex differences in cardiac structure and function following acute myocardial infarction: Insights from the PARADISE‐MI echocardiographic substudy. European Journal of Heart Failure, (doi: 10.1002/ejhf.3472)
Jhund, P. S., Talebi, A., Henderson, A. D., Claggett, B. L., Vaduganathan, M., Desai, A. S., Lam, C. S.P., Pitt, B., Senni, M., Shah, S. J., Voors, A. A., Zannad, F., Solomon, S. D., McMurray, J. J.V. (2024) Mineralocorticoid receptor antagonists in heart failure: an individual patient level meta-analysis. Lancet, 404, pp. 1119-1131. (doi: 10.1016/S0140-6736(24)01733-1)
Anderson, J. J., Deo, S. V., Welsh, P., Mackay, D. F., Ho, F. K., Ferguson, L. D., Celis-Morales, C., Gill, J.R., Pell, J. P., Sattar, N. (2024) In which common chronic conditions can (or cannot) obesity and lifestyle factors explain higher concentrations of C-reactive protein? Diabetes, Obesity and Metabolism, (doi: 10.1111/dom.15949)
Pabon, M. A., Vaduganathan, M., Claggett, B. L., Chatur, S., Siqueira, S., Marti‐Castellote, P., de Boer, R. A., Hernandez, A. F., Inzucchi, S. E., Kosiborod, M. N., Lam, C. S.P., Martinez, F., Shah, S. J., Desai, A. S., Jhund, P. S., McMurray, J. J.V., Solomon, S. D., Vardeny, O. (2024) In‐hospital course of patients with heart failure with improved ejection fraction in the DELIVER trial. European Journal of Heart Failure, (doi: 10.1002/ejhf.3410)
Valentova, M., Vatic, M., Garfias-Veitl, T., Sandek, A., Bekfani, T., Jankowska, E. A., Cleland, J. G.F., Clark, A. L., Lainscak, M., Ahmed, A., Jauert, N., Hasenfuss, G., Anker, S. D., Doehner, W., von Haehling, S. (2024) Diabetes mellitus is associated with low exercise capacity and impaired peripheral vasodilation in patients with heart failure – a propensity score-matched stud. Diabetes Research and Clinical Practice,
Greene, S. J. et al. (2024) Cardiovascular and renal treatment in heart failure patients with hyperkalemia or high risk of hyperkalemia: rationale and design of the CARE-HK in HF registry. Journal of Cardiac Failure, (doi: 10.1016/j.cardfail.2024.08.048)
Cuthbert, J. J., Cleland, J. G. F., Pellicori, P., Clark, A. L. (2024) Natriuresis guided diuresis in patients admitted to hospital with heart failure – barking up the wrong tree? Journal of Cardiac Failure,
Gallacher, K. I., Petrie, D., Rasmussen Pennington, D., McGuire, P., Quinn, T. J. (2024) Stroke recovery – what are people talking about on Twitter? A content analysis. Disability and Rehabilitation,
Kidd, L., Brown, J., Mason, H., Quinn, T., Gallacher, K. I., Jones, F., Fisher, R., Lebedis, T., Barber, M., Brennan, K., Gilmour, B., Fraser, C., Mooney, P., Taggart, A. (2024) A realist evaluation of mechanisms and contexts for facilitating the implementation of supported self-management in community stroke care (the IMPETUS study) Health and Social Care in the Community, 2024, (doi: 10.1155/2024/9198768)
Doherty, D. J., Abdin, A., Docherty, K. F. (2024) Heart failure medical therapy in the last years of life: prognosis and practicalities. European Journal of Heart Failure, (doi: 10.1002/ejhf.3450)
Lu, H., Claggett, B. L., Packer, M., Pfeffer, M. A., Lam, C. S.P., Zile, M. R., Desai, A. S., Jhund, P., Lefkowitz, M., McMurray, J. J.V., Solomon, S. D., Vaduganathan, M. (2024) Sacubitril/valsartan reduces incident anaemia and iron therapy utilization in heart failure: The PARAGON‐HF trial. European Journal of Heart Failure, (doi: 10.1002/ejhf.3414)
Morrow, A. et al. (2024) Zibotentan in microvascular angina: a randomized, placebo-controlled, crossover trial. Circulation, (doi: 10.1161/CIRCULATIONAHA.124.069901)
Al-Abdullah, L., Ahern, A., Welsh, P., Logue, J. (2024) A predictive model for medium-term weight loss response in people with type 2 diabetes engaging in behavioural weight management interventions. Diabetes, Obesity and Metabolism, 26, pp. 3653-3662. (doi: 10.1111/dom.15706)
Mc Causland, F. R., McGrath, M. M., Claggett, B. L., Barkoudah, E., East, C., Fernandez, A., Jering, K. S., Lewis, E. F., McMurray, J. J.V., Mody, F. V., Solomon, S. D., Tokmakova, M., van der Meer, P., Zhou, Y., Pfeffer, M. A. (2024) Acute changes in kidney function and outcomes following an acute myocardial infarction: Insights from PARADISE-MI. European Journal of Heart Failure, 26, pp. 1984-1992. (doi: 10.1002/ejhf.3386)
van der Meer, P., van Essen, B., Viljoen, C., Böhm, M., Jackson, A., Hilfiker-Kleiner, D., Hoevelmann, J., Mebazaa, A., Farhan, H. A., Goland, S., Ouwerkerk, W., Petrie, M. C., Seferović, P. M., Tromp, J., Sliwa, K., Bauersachs, J. (2024) Bromocriptine treatment and outcomes in peripartum cardiomyopathy: the EORP PPCM registry. European Heart Journal, (doi: 10.1093/eurheartj/ehae559)
Butt, J., Jhund, P. S., Docherty, K. F., Claggett, B. L., Vaduganathan, M., Bachus, E., Hernandez, A. F., Lam, C. S.P., Inzucchi, S. E., Martinez, F. A., de Boer, R. A., Kosiborod, M. N., Desai, A. S., Køber, L., Ponikowski, P., Sabatine, M. S., Solomon, S. D., McMurray, J. J.V. (2024) Dapagliflozin and timing of prior heart failure hospitalization a patient-level meta-analysis of DAPA-HF and DELIVER. JACC: Heart Failure, 12, pp. 1586-1599. (doi: 10.1016/j.jchf.2024.01.018)
Seferović, P. M., Paulus, W. J., Rosano, G., Polovina, M., Petrie, M. C., Jhund, P. S., Tschöpe, C., Sattar, N., Piepoli, M., Papp, Z., Standl, E., Mamas, M. A., Valensi, P., Linhart, A., Lalić, N., Ceriello, A., Döhner, W., Ristić, A., Milinković, I., Seferović, J., Cosentino, F., Metra, M., Coats, A. J.S. (2024) Diabetic myocardial disorder. A clinical consensus statement of the Heart Failure Association of the ESC and the ESC Working Group on Myocardial & Pericardial Diseases. European Journal of Heart Failure, 26, pp. 1893-1903. (doi: 10.1002/ejhf.3347)
Ryan, M., Taylor, D., Dodd, M., Spertus, J. A., Kosiborod, M. N., Shaukat, A., Docherty, K. F., Clayton, T., Perera, D., Petrie, M. C., REVIVED-BCIS2 Investigators, (2024) Effect of PCI on health status in ischemic left ventricular dysfunction: insights from REVIVED-BCIS2. JACC: Heart Failure, 12, pp. 1553-1562. (doi: 10.1016/j.jchf.2024.03.010)
Abdin, A., Kondo, T., Böhm, M., Jhund, P. S., Claggett, B. L., Vaduganathan, M., Hernandez, A. F., Lam, C. S.P., Inzucchi, S. E., Martinez, F. A., de Boer, R. A., Desai, A. S., Køber, L., Sabatine, M. S., Petersson, M., Bachus, E., Solomon, S. D., McMurray, J. (2024) Effects of dapagliflozin according to QRS duration across the spectrum of left ventricular ejection fraction: an analysis of DAPA-HF and DELIVER. European Journal of Heart Failure, 26, pp. 1952-1963. (doi: 10.1002/ejhf.3350)
Reza, N., Pellicori, P., Starling, R. C. (2024) REVOLUTION in heart failure care and SELECT highlights from the European Society of Cardiology-Heart Failure Association Heart Failure and World Congress on Acute Heart Failure 2024. Journal of Cardiac Failure, 30, pp. 1157-1160. (doi: 10.1016/j.cardfail.2024.05.004)
Tabish, T. A., Hussain, M. Z., Zhu, Y., Xu, J., Huang, W. E., Diotallevi, M., Narayan, R. J., Crabtree, M. J., Khademhosseini, A., Winyard, P. G., Lygate, C. (2024) Synthesis and characterization of amine-functionalized graphene as a nitric oxide-generating coating for vascular stents. Applied Physics Reviews, 11, (doi: 10.1063/5.0192379)
Butt, J. H., McMurray, J. J.V., Claggett, B. L., Jhund, P. S., Neuen, B. L., McCausland, F., Desai, A., Lam, C. S.P., Pitt, B., Pfeffer, M. A., Packer, M., Beldhuis, I., Voors, A. A., Zannad, F., Heerspink, H. J.L., Solomon, S. D., Vaduganathan, M. (2024) Therapeutic effects of heart failure medical therapies on standardized kidney outcomes: Comprehensive individual participant-level analysis of 6 randomized clinical trials. Circulation, (doi: 10.1161/circulationaha.124.071110)
Matsumoto, S., Henderson, A. D., Shen, L., Kondo, T., Yang, M., Campbell, R. T., Anand, I. S., de Boer, R. A., Desai, A. S., Lam, C. S.P., Maggioni, A. P., Martinez, F. A., Packer, M., Redfield, M. M., Rouleau, J. L., Van Veldhuisen, D. J., Vaduganathan, M., Zannad, F., Zile, M. R., Jhund, P. S., Solomon, S. D., McMurray, J. J.V. (2024) Beta‐blocker use and outcomes in patients with heart failure and mildly reduced and preserved ejection fraction. European Journal of Heart Failure, (doi: 10.1002/ejhf.3383)
Ponikowski, P. et al. (2024) Hospitalization of symptomatic patients with heart failure and moderate to severe functional mitral regurgitation treated with MitraClip: insights from RESHAPE-HF2. JACC: Heart Failure, (doi: 10.1016/j.jacc.2024.08.027)
McNeilly, S. et al. (2024) Collagen IV deficiency causes hypertrophic remodeling and endothelium-dependent hyperpolarization in small vessel disease with intracerebral hemorrhage. EBioMedicine, 107, (doi: 10.1016/j.ebiom.2024.105315)
Lipina, T., Li, S., Petrova, E. S., Amstislavskaya, T. G., Cameron, R. T., Elliott, C., Gondo, Y., McGirr, A., Mullins, J. G.L., Baillie, G. S., Woodgett, J. R., Clapcote, S. J. (2024) PDE4B missense variant increases susceptibility to post-traumatic stress disorder-relevant phenotypes in mice. Journal of Neuroscience,
Di Fiore, V., Del Punta, L., De Biase, N., Pellicori, P., Gargani, L., Dini, F. L., Armenia, S., Vigni, M. L., Maremmani, D., Masi, S., Taddei, S., Pugliese, N. R. (2024) Integrative assessment of congestion in heart failure using ultrasound imaging. Internal and Emergency Medicine,
Giannitsis, E., Frey, N., Jhund, P. S. (2024) Improving the rate of heart failure with improved ejection fraction. European Journal of Heart Failure, (doi: 10.1002/ejhf.3427)
Yang, M., Kondo, T., Anand, I. S., de Boer, R. A., Campbell, R. T., Køber, L., Lam, C. S.P., Maggioni, A. P., Martinez, F. A., O'Meara, E., Packer, M., Sabatine, M. S., Kerr Saraiva, J. F., Shah, S. J., Zannad, F., Zile, M. R., Jhund, P. S., Solomon, S. D., McMurray, J. J.V. (2024) Clinical characteristics and outcomes of patients aged 80 years and over with heart failure: Need for better treatment. European Journal of Heart Failure, (doi: 10.1002/ejhf.3417)
Liu, Q., Celis-Morales, C., Sattar, N., Welsh, P. (2024) Association of glycaemic control with intraocular pressure in a large general population: Results from the UK Biobank. Diabetes, Obesity and Metabolism, (doi: 10.1111/dom.15865)
Liu, Q., Celis-Morales, C., Sattar, N., Welsh, P. (2024) Association of glycemic control with intraocular pressure in a large general population: results from the UK Biobank. Diabetes, Obesity and Metabolism, (doi: 10.1111/dom.15865)
Graham, F. J., Guha, K., Cleland, J. G., Kalra, P. R. (2024) Treating iron deficiency in patients with heart failure: what, why, when, how, where and who. Heart, (doi: 10.1136/heartjnl-2022-322030)
Butt, J. H., Thune, J. J., Nielsen, J. C., Haarbo, J., Videbæk, L., Gustafsson, F., Kristensen, S. L., Bruun, N. E., Eiskjær, H., Brandes, A., Hassager, C., Svendsen, J. H., Høfsten, D. E., Torp‐Pedersen, C., Schou, M., Pehrson, S., Packer, M., McMurray, J. J.V., Køber, L. (2024) Anthropometric measures and long‐term mortality in non‐ischaemic heart failure with reduced ejection fraction: Questioning the obesity paradox. European Journal of Heart Failure, (doi: 10.1002/ejhf.3424)
Cleland, J., Pellicori, P., Graham, F. J., Lane, R., Petrie, M. C., Ahmed, F., Squire, I. B., Ludman, A., Japp, A., Al-Mohammad, A., Clark, A. L., Szwejkowski, B., Critoph, C., Chong, V., Schiff, R., Nageh, T., Glover, J., McMurray, J. J.V., Thomson, E. A., Robertson, M., Ford, I., Kalra, P. A., Kalra, P. R. (2024) The IRONMAN trial of intravenous iron for heart failure. Adjudication of hospitalizations and deaths. Journal of the American College of Cardiology,
Thongyim, S., Wright, T. A., Sattayawat, P., Kaewkod, T., Baillie, G. S., Tragoolpua, Y., Jangsutthivorawat, S., Panya, A. (2024) Clinacanthus nutans extract lowers periodontal inflammation under high-glucose conditions via inhibiting NF-κB signaling pathway. Frontiers in Pharmacology, 15, (doi: 10.3389/fphar.2024.1410419)
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Jackson, A., Bauersachs, J., Petrie, M. C., van der Meer, P., Laroche, C., Farhan, H. A., Frogoudaki, A., Ibrahim, B., Fouad, D. A., Damasceno, A., Karaye, K., Goland, S., Maggioni, A. P., Briton, O., Sliwa, K. (2024) Outcomes at one year in women with peripartum cardiomyopathy: findings from the ESC EORP PPCM Registry. European Journal of Heart Failure, 26, pp. 34-42. (doi: 10.1002/ejhf.3055)
Chivardi, C. et al. (2024) Percutaneous revascularization for ischemic left ventricular dysfunction: Cost-effectiveness analysis of the REVIVED-BCIS2 trial. Circulation: Cardiovascular Quality and Outcomes, 17, (doi: 10.1161/circoutcomes.123.010533)
Schou, M., Claggett, B., Miao, Z. M., Fernandez, A., Filippatos, G., Granger, C., Jering, K., Maggioni, A. P., McCausland, F., Villota, J. N., Rouleau, J.‐L., Mody, F. V., van der Meer, P., Vinereanu, D., McGrath, M., Zhou, Y., Mann, D. L., Solomon, S. D., Steg, P. G., Braunwald, E., McMurray, J. J.V., Pfeffer, M. A., Køber, L. (2024) Sacubitril/valsartan compared to ramipril in high‐risk post‐myocardial infarction patients stratified according to use of mineralocorticoid receptor antagonists: insight from the PARADISE MI trial. European Journal of Heart Failure, 26, pp. 130-139. (doi: 10.1002/ejhf.3079)
Lala, A., Hamo, C. E., Bozkurt, B., Fiuzat, M., Blumer, V., Bukhoff, D., Butler, J., Costanzo, M. R., Felker, G. M., Filippatos, G., Konstam, M. A., McMurray, J. J.V., Mentz, R. J., Metra, M., Psotka, M. A., Solomon, S. D., Teerlink, J., Abraham, W. T., O’Connor, C. M. (2024) Standardized definitions for evaluation of acute decompensated heart failure therapies: HF-ARC expert panel paper. JACC: Heart Failure, 12, pp. 1-15. (doi: 10.1016/j.jchf.2023.09.030)
Docherty, K. F., McMurray, J. J.V., Diaz, R., Felker, G. M., Metra, M., Solomon, S. D., Adams, K. F., Böhm, M., Brinkley, D. M., Echeverria, L. E., Goudev, A. R., Howlett, J. G., Lund, M., Ponikowski, P., Yilmaz, M. B., Zannad, F., Claggett, B. L., Miao, Z. M., Abbasi, S. A., Divanji, P., Heitner, S. B., Kupfer, S., Malik, F. I., Teerlink, J. R. (2024) The effect of omecamtiv mecarbil in hospitalized patients as compared with outpatients with HFrEF: an analysis of GALACTIC-HF. Journal of Cardiac Failure, 30, pp. 26-35. (doi: 10.1016/j.cardfail.2023.08.020)
Corbin, L. J., Hughes, D. A., Bull, C. J., Vincent, E. E., Smith, M. L., McConnachie, A., Messow, C.-M., Welsh, P., Taylor, R., Lean, M. E.J., Sattar, N., Timpson, N. J. (2024) The metabolomic signature of weight loss and remission in the Diabetes Remission Clinical Trial (DiRECT) Diabetologia, 67, pp. 74-87. (doi: 10.1007/s00125-023-06019-x)
McFall, A., Graham, D., Nicklin, S. A., Work, L. M. (2024) Unscheduled changes in pre-clinical stroke model housing contributes to variance in physiological and behavioural data outcomes: a post hoc analysis. Brain and Neuroscience Advances, 8, (doi: 10.1177/23982128241238934)
Astrauskaitė, G., Williamson, L., Mohanan, S., Moreno, S. M., Kinegawa, R., Boland, E., Huethorst, E., Smith, G., Müllenbroich, C. (2024) Fast Axial Scanning with Remote Focusing for Multiphoton Microscopy of Acute Rabbit Ventricular Slices to Follow Action Potentials Transmurally. (doi: 10.1364/CLEO_SI.2024.SF2B.1)
Ward, J., Cox, S. R., Quinn, T., Lyall, L. M., Strawbridge, R. J., Russell, E., Pell, J. P., Stewart, W., Cullen, B., Whalley, H., Lyall, D. M. (2024) Head motion in the UK Biobank imaging subsample: longitudinal stability, associations with psychological and physical health, and risk of incomplete data. Brain Communications, 6, (doi: 10.1093/braincomms/fcae220)
McMahon, D., Dixon, D., Quinn, T., Gallacher, K. I. (2024) The Acceptability of post-stroke cognitive testing through the lens of the theory of acceptability, a qualitative study. Cerebral Circulation - Cognition and Behavior, 6, (doi: 10.1016/j.cccb.2023.100197)
2023
Caiazzo, E., Sharma, M., Rezig, A. O.M., Morsy, M. I., Czesnikiewicz-Guzik, M., Ialenti, A., Sulicka-Grodzicka, J., Pellicori, P., Crouch, S. H., Schutte, A. E., Bruzzese, D., Maffia, P., Guzik, T. J. (2023) Circulating cytokines and risk of developing hypertension: a systematic review and meta-analysis. Pharmacological Research, 200, (doi: 10.1016/j.phrs.2023.107050)
Henderson, A. D., Carlile, O., Dillingham, I., FC. Butler-Cole, B., Tomlin, K., Jit, M., Tomlinson, L. A., Marks, M., Briggs, A., Lin, L.-Y., Bates, C., Parry, J., CJ. Bacon, S., Goldacre, B., Mehrkar, A., Herrett, E., Eggo, R. M. (2023) Cohort profile: OpenPROMPT. medRxiv, (doi: 10.1101/2023.12.21.23300369)
Lin, L.-Y., Henderson, A. D., Carlile, O., Dillingham, I., FC. Butler-Cole, B., Marks, M., Briggs, A., Jit, M., Tomlinson, L. A., Bates, C., Parry, J., CJ. Bacon, S., Goldacre, B., Mehrkar, A., MacKenna, B., Eggo, R. M., Herrett, E. (2023) Healthcare utilisation in people with long COVID: an OpenSAFELY cohort study. medRxiv, (doi: 10.1101/2023.12.21.23300305)
Lee, M. M.Y., Lean, M. E.J., Sattar, N., Petrie, M. C. (2023) Appetite and its regulation: Are there palatable interventions for heart failure? Current Heart Failure Reports, 21, pp. 1-4. (doi: 10.1007/s11897-023-00637-7)
Kosiborod, M. N., Borlaug, B. A., Petrie, M. C. (2023) Semaglutide and heart failure with preserved ejection fraction and obesity. Reply. New England Journal of Medicine, 389, pp. 2398-2399. (doi: 10.1056/NEJMc2312296)
Glen, C., Adam, S., Coats, C. J., Lang, N. N. (2023) Reply: Cardiotoxicity of BRAF/MEK inhibitors according to HFA/ICOS cardiotoxicity risk category. JACC: CardioOncology, 5, pp. 850. (doi: 10.1016/j.jaccao.2023.10.003)
Ostrominski, J. W., Vaduganathan, M., Selvaraj, S., Claggett, B. L., Miao, Z. M., Desai, A. S., Jhund, P. S., Kosiborod, M. N., Lam, C. S.P., Inzucchi, S. E., Martinez, F. A., de Boer, R. A., Hernandez, A. F., Shah, S. J., Petersson, M., Maria Langkilde, A., McMurray, J. J.V., Solomon, S. D. (2023) Dapagliflozin and apparent treatment-resistant hypertension in heart failure with mildly reduced or preserved ejection fraction: The DELIVER trial. Circulation, 148, pp. 1945-1957. (doi: 10.1161/CIRCULATIONAHA.123.065254)
Welsh, S. A., Hussey, K., Brittenden, J., Orr, D. J., Quinn, T. (2023) Frailty Assessment in Vascular OUtpatients Review (FAVOUR) PROTOCOL – single-centre prospective cohort study comparing feasibility and prognostic value of commonly used frailty assessment tools. BMJ Open, 13, (doi: 10.1136/bmjopen-2023-079387)
Welsh, P., Kimenai, D. M., Shah, A. S.V., Gadd, D. A., Marioni, R. E., Woodward, M., Sudlow, C. L.M., Campbell, A., Cleland, J. G.F., Pellicori, P., Hayward, C., Mills, N. L., Sattar, N. (2023) Multiple cardiac biomarkers to improve prediction of cardiovascular events: findings from the Generation Scotland Scottish Family Health Study. Clinical Chemistry, 70, pp. 403-413. (doi: 10.1093/clinchem/hvad205)
Taylor-Rowan, M., Alharthi, A., Noel-Storr, A. H., Myint, P. K., Stewart, C., McCleery, J., Quinn, T. J. (2023) Anticholinergic deprescribing interventions for reducing risk of cognitive decline or dementia in older adults with and without prior cognitive impairment. Cochrane Database of Systematic Reviews, 2023, (doi: 10.1002/14651858.CD015405.pub2)
McMurray, J. J.V., Docherty, K. F., de Boer, R. A., Hammarstedt, A., Kitzman, D. W., Kosiborod, M. N., Langkilde, A. M., Reicher, B., Senni, M., Shah, S. J., Wilderäng, U., Verma, S., Solomon, S. D. (2023) Effect of Dapagliflozin Versus Placebo on Symptoms and 6-Minute Walk Distance in Patients With Heart Failure: The DETERMINE Randomized Clinical Trials. Circulation, (doi: 10.1161/CIRCULATIONAHA.123.065061)
Vardeny, O., Fang, J. C., Desai, A. S., Jhund, P. S., Claggett, B., Vaduganathan, M., de Boer, R. A., Hernandez, A. F., Lam, C. S. P., Inzucchi, S. E., Martinez, F. A., Kosiborod, M. N., DeMets, D., O’Meara, E., Zieroth, S., Comin-Colet, J., Drozdz, J., Chiang, C.-E., Kitakaze, M., Petersson, M., Lindholm, D., Langkilde, A. M., McMurray, J. J.V., Solomon, S. D. (2023) Author Correction: Dapagliflozin in heart failure with improved ejection fraction: a prespecified analysis of the DELIVER trial. Nature Medicine, 29, pp. 3269-3269. (doi: 10.1038/s41591-023-02302-x)
Matsumoto, S., Kondo, T., Yang, M., Campbell, R. T., Docherty, K. F., de Boer, R. A., Desai, A. S., Lam, C. S.P., Packer, M., Pitt, B., Rouleau, J. L., Vaduganathan, M., Zannad, F., Zile, M. R., Solomon, S. D., Jhund, P. S., McMurray, J. J.V. (2023) Calcium channel blocker use and outcomes in patients with heart failure and mildly reduced and preserved ejection fraction. European Journal of Heart Failure, 25, pp. 2202-2214. (doi: 10.1002/ejhf.3044)
McErlane, J., McCall, P., Willder, J., Berry, C., Shelley, B. (2023) Cardiac biomarkers and right ventricular dysfunction are independently associated with one year mortality in patients with COVID-19 receiving mechanical ventilation: a prospective cohort study. CHEST Critical Care, 1, (doi: 10.1016/j.chstcc.2023.100015)
Fletcher, R. A., Jongs, N., Chertow, G. M., McMurray, J. J.V., Arnott, C., Jardine, M. J., Mahaffey, K. W., Perkovic, V., Rockenschaub, P., Rossing, P., Correa-Rotter, R., Toto, R. D., Vaduganathan, M., Wheeler, D. C., Heerspink, H. J.L., Neuen, B. L. (2023) Effect of SGLT2 inhibitors on discontinuation of renin–angiotensin system blockade: A joint analysis of the CREDENCE and DAPA-CKD trials. Journal of the American Society of Nephrology, 34, pp. 1965-1975. (doi: 10.1681/ASN.0000000000000248)
Kondo, T., Butt, J. H., Curtain, J. P., Jhund, P. S., Docherty, K. F., Claggett, B. L., Vaduganathan, M., Bachus, E., Hernandez, A. F., Lam, C. S.P., Inzucchi, S. E., Martinez, F. A., de Boer, R. A., Kosiborod, M. N., Desai, A. S., Køber, L., Ponikowski, P., Sabatine, M. S., Solomon, S. D., McMurray, J. J.V. (2023) Efficacy of dapagliflozin according to heart rate: A patient-level pooled analysis of DAPA-HF and DELIVER. Circulation: Heart Failure, 16, (doi: 10.1161/CIRCHEARTFAILURE.123.010898)
Da Silva Costa, A., Ghouri, I., Johnston, A., Mcglynn, K., McNair, A., Bowman, P., Malik, N., Hurren, J., Bingelis, T., Dunne, M., Smith, G. L., Kemi, O. J. (2023) Electrically stimulated in vitro heart cell mimic of acute exercise reveals novel immediate cellular responses to exercise: Reduced contractility and metabolism, but maintained calcium cycling and increased myofilament calcium sensitivity. Cell Biochemistry and Function, 41, pp. 1147-1161. (doi: 10.1002/cbf.3847)
Bhatt, A. S., Kosiborod, M. N., Claggett, B. L., Miao, Z. M., Vaduganathan, M., Lam, C. S. P., Hernandez, A. F., Martinez, F. A., Inzucchi, S. E., Shah, S. J., de Boer, R. A., Jhund, P. S., Desai, A. S., Fang, J. C., Han, Y., Comin‐Colet, J., Drożdż, J., Vardeny, O., Merkely, B., Lindholm, D., Peterson, M., Langkilde, A. M., McMurray, J. J. V., Solomon, S. D. (2023) Impact of COVID‐19 in patients with heart failure with mildly reduced or preserved ejection fraction enrolled in the DELIVER trial. European Journal of Heart Failure, 25, pp. 2177-2188. (doi: 10.1002/ejhf.3043)
Zahir Anjum, D., Strange, J. E., Fosbøl, E., Garred, C. H., Malik, M. E., Andersson, C., Jhund, P. S., McMurray, J. J.V., Petrie, M. C., Kober, L., Schou, M. (2023) Initiation of medical therapy for heart failure patients according to kidney function: a Danish nationwide study. Clinical Epidemiology, 15, pp. 855-866. (doi: 10.2147/clep.s412787)
Taylor-Rowan, M., Hafdi, M., Drozdowska, B., Elliott, E., Warlaw, J., Quinn, T. J. (2023) Physical and brain frailty in ischaemic stroke or TIA: shared occurrence and outcomes. A cohort study. European Stroke Journal, 8, pp. 1011-1020. (doi: 10.1177/23969873231186480)
Ali, M., Tibble, H., Brady, M. C., Quinn, T. J., Sunnerhagen, K. S., Venketasubramanian, N., Shuaib, A., Pandyan, A., Mead, G. (2023) Prevalence, trajectory and predictors of post stroke pain: retrospective analysis of pooled clinical trial datasets. Stroke, 54, pp. 3107-3116. (doi: 10.1161/STROKEAHA.123.043355)
Flett, A., Cebula, A., Nicholas, Z., Adam, R., Ewings, S., Prasad, S., Cleland, J. G.F., Eminton, Z., Curzen, N. (2023) Rationale and study protocol for the BRITISH randomised trial (using cardiovascular magnetic resonance identified scar as the Benchmark Risk Indication Tool for Implantable cardioverter defibrillators in patients with non-ischaemic cardiomyopathy and severe systolic heart failure) American Heart Journal, 266, pp. 149-158. (doi: 10.1016/j.ahj.2023.09.008)
Pabon, M., Cunningham, J., Claggett, B., Felker, G. M., McMurray, J. J.V., Metra, M., Diaz, R., Wang, X., Arias-Mendoza, A., Bonderman, D., Crespo-Leiro, M., Fonseca, C., Goncalvesova, E., Lund, M., O’Meara, E., Sliwa-Hahnle, K., Malik, F. I., Solomon, S. D., Teerlink, J. R. (2023) Sex differences in heart failure with reduced ejection fraction in the GALACTIC-HF trial. JACC: Heart Failure, 11, pp. 1729-1738. (doi: 10.1016/j.jchf.2023.07.029)
Nurfianti, A., Quinn, T.J., Kotronoulas, G., Kidd, L. (2023) Survey of Nurses’ Roles in, and Education Needs for, Assessing and Managing Post-Stroke Cognitive Impairment (PSCI) in Indonesia.
Nurfianti, A., Chaiyapoom, N., Quinn, T.J., Lumsden, J., Kidd, L. (2023) What are Nurses' Roles in Assessing and Managing Post-stroke Cognitive Impairment? A Systematic Review of Stroke Clinical Practice Guidelines.
Tabish, T. A., Zhu, Y., Shukla, S., Kadian, S., Sangha, G. S., Lygate, C. A., Narayan, R. J. (2023) Graphene nanocomposites for real-time electrochemical sensing of nitric oxide in biological systems. Applied Physics Reviews, 10, (doi: 10.1063/5.0162640)
Berry, C. et al. (2023) Mental health symptoms and illness trajectory following COVID-19 hospitalization: A cohort study. Heart and Mind, 7, pp. 235-245. (doi: 10.4103/hm.HM-D-23-00037)
Goudswaard, L. J., Smith, M. L., Hughes, D. A., Taylor, R., Lean, M., Sattar, N., Welsh, P., McConnachie, A., Blazeby, J. M., Rogers, C. A., Suhre, K., Zaghlool, S. B., Hers, I., Timpson, N. J., Corbin, L. J. (2023) Using trials of caloric restriction and bariatric surgery to explore the effects of body mass index on the circulating proteome. Scientific Reports, 13, (doi: 10.1038/s41598-023-47030-x)
Chatur, S., Vaduganathan, M., Claggett, B. L., Cunningham, J. W., Docherty, K. F., Desai, A. S., Jhund, P. S., De Boer, R. A., Hernandez, A. F., Inzucchi, S. E., Kosiborod, M. N., Lam, C. S. P., Martinez, F. A., Shah, S. J., Petersson, M., Langkilde, A.-M., McMurray, J. J. V., Solomon, S. D. (2023) Outpatient worsening among patients with mildly reduced and preserved ejection fraction heart failure in the DELIVER trial. Circulation, 148, pp. 1735-1745. (doi: 10.1161/circulationaha.123.066506)
Belch, J. J.F., Elder, A., Bartlett, S., Fardon, T., Flinn, K., Hughes, R. C., Miller, M. R., Newby, D., Quinn, T., Slater, M. (2023) Children are especially vulnerable to air pollution: We need data on transport emissions near schools. British Medical Journal, 383, (doi: 10.1136/bmj.p2675)
Miranda, F., Gonzalez, F., Plana, M. N., Zamora, J., Quinn, T. J., Seron, P. (2023) Confusion Assessment Method for the Intensive Care Unit (CAM-ICU) for the diagnosis of delirium in adults in critical care settings. Cochrane Database of Systematic Reviews, 11, (doi: 10.1002/14651858.CD013126.pub2)
Henriksen, P. A. et al. (2023) Multicenter, prospective, randomized controlled trial of high-sensitivity cardiac troponin I–guided combination angiotensin receptor blockade and beta-blocker therapy to prevent anthracycline cardiotoxicity: The Cardiac CARE trial. Circulation, 148, pp. 1680-1690. (doi: 10.1161/CIRCULATIONAHA.123.064274)
Mc Causland, F. R., Claggett, B. L., Vaduganathan, M., Desai, A., Jhund, P., Vardeny, O., Fang, J. C., de Boer, R. A., Docherty, K. F., Hernandez, A. F., Inzucchi, S. E., Kosiborod, M. N., Lam, C. S. P., Martinez, F., Saraiva, J. F. K., McGrath, M. M., Shah, S. J., Verma, S., Langkilde, A. M., Petersson, M., McMurray, J. J. V., Solomon, S. D. (2023) Decline in estimated glomerular filtration rate after dapagliflozin in heart failure with mildly reduced or preserved ejection fraction: A prespecified secondary analysis of the DELIVER randomized clinical trial. JAMA Cardiology, 9, pp. 144-152. (doi: 10.1001/jamacardio.2023.4664)
Chatur, S., Vaduganathan, M., Claggett, B. L., Mc Causland, F. R., Desai, A. S., Jhund, P. S., de Boer, R. A., Hernandez, A. F., Inzucchi, S. E., Kosiborod, M. N., Lam, C. S.P., Martinez, F. A., Shah, S. J., Sabatine, M. S., Kober, L., Ponikowski, P., Merkely, B., Petersson, M., Langkilde, A. M., McMurray, J. J.V., Solomon, S. D. (2023) Dapagliflozin in patients with heart failure and deterioration in renal function. Journal of the American College of Cardiology, 82, pp. 1854-1863. (doi: 10.1016/j.jacc.2023.08.026)
Leong, D. P., Joseph, P., McMurray, J. J.V., Rouleau, J., Maggioni, A. P., Lanas, F., Sharma, S. K., Núñez, J., Mohan, B., Celik, A., Abdullakutty, J., Ogah, O. S., Mielniczuk, L. M., Balasubramanian, K., McCready, T., Grinvalds, A., Yusuf, S. (2023) Frailty and outcomes in heart failure patients from high-, middle-, and low-income countries. European Heart Journal, 44, pp. 4435-4444. (doi: 10.1093/eurheartj/ehad595)
Ostrominski, J. W., Thierer, J., Claggett, B. L., Miao, Z. M., Desai, A. S., Jhund, P. S., Kosiborod, M. N., Lam, C. S.P., Inzucchi, S. E., Martinez, F. A., de Boer, R. A., Hernandez, A. F., Shah, S. J., Petersson, M., Langkilde, A. M., McMurray, J. J.V., Solomon, S. D., Vaduganathan, M. (2023) Cardio-renal-metabolic overlap, outcomes, and dapagliflozin in heart failure with mildly reduced or preserved ejection fraction. JACC: Heart Failure, 11, pp. 1491-1503. (doi: 10.1016/j.jchf.2023.05.015)
Petermann-Rocha, F., Deo, S., Lyall, D., Orkaby, A. R., Quinn, T. J., Sattar, N., Celis-Morales, C., Pell, J. P., Ho, F. K. (2023) Association between the AHA Life's Essential 8 score and incident all-cause dementia: a prospective cohort study from UK Biobank. Current Problems in Cardiology, 48, (doi: 10.1016/j.cpcardiol.2023.101934)
Vissing, C. R. et al. (2023) Cardiac remodeling in subclinical hypertrophic cardiomyopathy: the VANISH randomized clinical trial. JAMA Cardiology, 8, pp. 1083-1088. (doi: 10.1001/jamacardio.2023.2808)
Ho, L., Lloyd, K., Taylor-Rowan, M., Dawson, S., Logan, M., Leitc, S., Quinn, T. J., Shenkin, S. D., Parry, S. W., Jarman, H., Henderson, E. J. (2023) Comparing research priority-setting partnerships for older adults across international health care systems: a systematic review. Journal of the American Medical Directors Association, 24, pp. 1726-1745. (doi: 10.1016/j.jamda.2023.09.003)
Ostrominski, J. W., Claggett, B. L., Packer, M., Pfeffer, M. A., Lam, C. S.P., Zile, M. R., Desai, A. S., Jhund, P. S., Lefkowitz, M., McMurray, J. J.V., Solomon, S. D., Vaduganathan, M. (2023) Duration of heart failure with preserved ejection fraction and outcomes with sacubitril/valsartan: insights from the PARAGON-HF trial. Journal of Cardiac Failure, 29, pp. 1494-1503. (doi: 10.1016/j.cardfail.2023.05.003)
Heerspink, H. J. L., Vart, P., Jongs, N., Neuen, B. L., Bakris, G., Claggett, B., Vaduganathan, M., McCausland, F., Docherty, K. F., Jhund, P. S.,, Solomon, S. D., Perkovic, V., McMurray, J. J. V. (2023) Estimated lifetime benefit of novel pharmacological therapies in patients with type 2 diabetes and chronic kidney disease: a joint analysis of randomized controlled clinical trials. Diabetes, Obesity and Metabolism, 25, pp. 3327-3336. (doi: 10.1111/dom.15232)
Bhatt, A. S., Vaduganathan, M., Claggett, B. L., Fonarow, G. C., Packer, M., Pfeffer, M. A., Shah, S. J., Shen, X., Cristino, J., McMurray, J. J.V., Solomon, S. D., Gaziano, T. A. (2023) Health and economic evaluation of sacubitril-valsartan for heart failure management. JAMA Cardiology, 8, pp. 1041-1048. (doi: 10.1001/jamacardio.2023.3216)
Butt, J. H., Lu, H., Kondo, T., Bachus, E., de Boer, R. A., Inzucchi, S. E., Jhund, P. S., Kosiborod, M. N., Lam, C. S.P., Martinez, F. A., Vaduganathan, M., Solomon, S. D., McMurray, J. J.V. (2023) Heart failure, chronic obstructive pulmonary disease and efficacy and safety of dapagliflozin in heart failure with mildly reduced or preserved ejection fraction: insights from DELIVER. European Journal of Heart Failure, 25, pp. 2078-2090. (doi: 10.1002/ejhf.3000)
Purcell, C., Purvis, A., Cleland, J. G.F., Cowie, A., Dalal, H. M., Ibbotson, T., Murphy, C., Taylor, R. S. (2023) Home-based cardiac rehabilitation for people with heart failure and their caregivers: a mixed-methods analysis of the roll out an evidence-based programme in Scotland (SCOT:REACH-HF study) European Journal of Cardiovascular Nursing, 22, pp. 804-813. (doi: 10.1093/eurjcn/zvad004)
Farzi, M., Coveney, S., Afzali, M., Zdora, M.‐C., Lygate, C. A., Rau, C., Frangi, A. F., Dall'Armellina, E., Teh, I., Schneider, J. E. (2023) Measuring cardiomyocyte cellular characteristics in cardiac hypertrophy using diffusion‐weighted MRI. Magnetic Resonance in Medicine, 90, pp. 2144-2157. (doi: 10.1002/mrm.29775)
Cooper, N., Germeni, E., Freeman, S. C., Jaiswal, N., Nevill, C. R., Sutton, A. J., Taylor-Rowan, M., Quinn, T. J. (2023) New horizons in evidence synthesis for older adults. Age and Ageing, 52, (doi: 10.1093/ageing/afad211)
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2021
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2020
Brown, R., Welsh, P., Logue, J. (2020) Systematic review of clinical guidelines for lipid-lowering in the secondary prevention of cardiovascular disease events. Open Heart, 7, (doi: 10.1136/openhrt-2020-001396)
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Macdougall, I. C., White, C., Anker, S. D., Bhandari, S., Farrington, K., Karla, P. A., McMurray, J. J.V., Murray, H., Tomson, C. R.V., Wheeler, D. C., Winearls, C. G., Ford, I. (2019) Correction: Intravenous iron in patients undergoing maintenance hemodialysis. New England Journal of Medicine, 380, pp. 502. (doi: 10.1056/NEJMx180044)
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Cameron, A. C., Rossitto, G., Lang, N. N., Touyz, R. M. (2019) Antihypertensive drugs and vascular health. Springer
Quinn, T. J., Makin, S., Doubal, F., Staals, J. (2019) Cerebral small vessel disease and vascular cognitive impairment. Springer
Purnama Sidik, N., McCartney, P., Berry, C. (2019) Coronary microvascular disease. Springer
Burton, J. K., Quinn, T. J., Fisher, M. (2019) Diabetes and stroke. Practical Diabetes, 36, pp. 126-131. (doi: 10.1002/pdi.2230)
Schultheiss, H.-P., Fairweather, D., Caforio, A. L.P., Escher, F., Hershberger, R. E., Lipshultz, S. E., Liu, P. P., Matsumori, A., Mazzanti, A., McMurray, J., Priori, S. G. (2019) Dilated cardiomyopathy. Nature Reviews Disease Primers, 5, (doi: 10.1038/s41572-019-0084-1)
Pfeiffer-Kaushik, E. R., Smith, G. L., Cai, B., Dempsey, G. T., Hortigon-Vinagre, M. P., Zamora, V., Feng, S., Ingermanson, R., Zhu, R., Hariharan, V., Nguyen, C., Pierson, J., Gintant, G. A., Tung, L. (2019) Electrophysiological characterization of drug response in hSC-derived cardiomyocytes using voltage-sensitive optical platforms. Journal of Pharmacological and Toxicological Methods, 99, (doi: 10.1016/j.vascn.2019.106612)
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Jackson, A. M., Jhund, P. S. (2019) Heart failure with reduced ejection fraction. Springer
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Blair, C. M., Walsh, N., Littman, B. H., Marcoux, F. W., Baillie, G. S. (2019) Targeting B-Raf inhibitor resistant melanoma with novel cell penetrating peptide disrupters of PDE8A – C-Raf. BMC Cancer, 19, (doi: 10.1186/s12885-019-5489-4)
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2018
Lemme, M., Ulmer, B. M., Lemoine, M. D., Zech, A. T.L., Flenner, F., Ravens, U., Reichenspurner, H., Rol-Garcia, M., Smith, G., Hansen, A., Christ, T., Eschenhagen, T. (2018) Atrial-like engineered heart tissue: an in vitro model of the human atrium. Stem Cell Reports, 11, pp. 1378-1390. (doi: 10.1016/j.stemcr.2018.10.008)
Tromp, J., MacDonald, M. R., Tay, W. T., Teng, T.-H. K., Hung, C.-L., Narasimhan, C., Shimizu, W., Ling, L. H., Ng, T. P., Yap, J., McMurray, J. J.V., Zile, M. R., Richards, A. M., Anand, I. S., Lam, C. S.P. (2018) Heart failure with preserved ejection fraction in the young. Circulation, 138, pp. 2763-2773. (doi: 10.1161/CIRCULATIONAHA.118.034720)
Ford, T. J., Stanley, B., Good, R., Rocchiccioli, P., McEntegart, M., Watkins, S., Eteiba, H., Shaukat, A., Lindsay, M., Robertson, K., Hood, S., McGeoch, R., McDade, R., Yii, E., Sidik, N., McCartney, P., Corcoran, D., Collison, D., Rush, C., McConnachie, A., Touyz, R., Oldroyd, K., Berry, C. (2018) Stratified medical therapy using invasive coronary function testing in angina: CorMicA trial. Journal of the American College of Cardiology, 72, pp. 2841-2855. (doi: 10.1016/j.jacc.2018.09.006)
Ford, T. J., Rocchiccioli, P., Good, R., McEntegart, M., Eteiba, H., Watkins, S., Shaukat, A., Lindsay, M., Robertson, K., Hood, S., Yii, E., Sidik, N., Harvey, A., Montezano, A. C., Beattie, E., Haddow, L., Oldroyd, K. G., Touyz, R. M., Berry, C. (2018) Systemic microvascular dysfunction in microvascular and vasospastic angina. European Heart Journal, 39, pp. 4086-4097. (doi: 10.1093/eurheartj/ehy529)
Strembitska, A., Mancini, S. J., Gamwell, J. M., Palmer, T. M., Baillie, G. S., Salt, I. P. (2018) A769662 inhibits insulin-stimulated Akt activation in human macrovascular endothelial cells independent of AMP-activated protein kinase. International Journal of Molecular Sciences, 19, (doi: 10.3390/ijms19123886)
Srivastava, P. K., Claggett, B. L., Solomon, S. D., McMurray, J. J.V., Packer, M., Zile, M. R., Desai, A. S., Rouleau, J. L., Swedberg, K., Fonarow, G. C. (2018) Estimated 5-year number needed to treat to prevent cardiovascular death or heart failure hospitalization with angiotensin receptor-neprilysin inhibition vs standard therapy for patients with heart failure with reduced ejection fraction: an analysis of data from the PARADIGM-HF trial. JAMA Cardiology, 3, pp. 1226-1231. (doi: 10.1001/jamacardio.2018.3957)
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Adamson, P. D., Hunter, A., Madsen, D. M., Shah, A. S.V., McAllister, D. A., Pawade, T. A., Williams, M. C., Berry, C., Boon, N. A., Flather, M., Forbes, J., McLean, S., Roditi, G., Timmis, A. D., van Beek, E. J.R., Dweck, M. R., Mickley, H., Mills, N. L., Newby, D. E. (2018) High-sensitivity cardiac troponin I and the diagnosis of coronary artery disease in patients with suspected angina pectoris. Circulation: Cardiovascular Quality and Outcomes, 11, (doi: 10.1161/CIRCOUTCOMES.117.004227)
van der Meer, P., Grote Beverborg, N., Pfeffer, M. A., Olson, K., Anand, I. S., Westenbrink, B. D., McMurray, J. J.V., Swedberg, K., Young, J. B., Solomon, S. D., van Veldhuisen, D. J. (2018) Hyporesponsiveness to darbepoetin alfa in patients with heart failure and anemia in the RED-HF study (Reduction of Events by Darbepoetin Alfa in Heart Failure): clinical and prognostic associations. Circulation: Heart Failure, 11, (doi: 10.1161/CIRCHEARTFAILURE.117.004431)
Cleland, J. G.F. (2018) Physicians Addicted to Prescribing Aspirin-a Disorder Of Cardiologists (PAPA-DOC) Syndrome: the headache of nonevidence-based medicine for ischemic heart disease? JACC: Heart Failure, 6, pp. 168-171. (doi: 10.1016/j.jchf.2017.11.014)
Platz, E., Jhund, P. S., Claggett, B. L., Pfeffer, M. A., Swedberg, K., Granger, C. B., Yusuf, S., Solomon, S. D., McMurray, J. J. (2018) Prevalence and prognostic importance of precipitating factors leading to heart failure hospitalization: recurrent hospitalizations and mortality. European Journal of Heart Failure, 20, pp. 295-303. (doi: 10.1002/ejhf.901)
Nikolaidou, T., Pellicori, P., Zhang, J., Kazmi, S., Goode, K. M., Cleland, J. G., Clark, A. L. (2018) Prevalence, predictors, and prognostic implications of PR interval prolongation in patients with heart failure. Clinical Research in Cardiology, 107, pp. 108-119. (doi: 10.1007/s00392-017-1162-6)
Welsh, P., Kou, L., Yu, C., Anand, I., van Veldhuisen, D. J., Maggioni, A. P., Desai, A. S., Solomon, S. D., Pfeffer, M. A., Cheng, S., Gullestad, L., Aukrust, P., Ueland, T., Swedberg, K., Young, J. B., Kattan, M. W., Sattar, N., McMurray, J. J.V. (2018) Prognostic importance of emerging cardiac, inflammatory, and renal biomarkers in chronic heart failure patients with reduced ejection fraction and anaemia: RED-HF study. European Journal of Heart Failure, 20, pp. 268-277. (doi: 10.1002/ejhf.988)
Emmens, J. E., Jones, D. J.L., Cao, T. H., Chan, D. C.S., Romaine, S. P.R., Quinn, P. A., Anker, S. D., Cleland, J. G., Dickstein, K., Filippatos, G., Hillege, H. L., Lang, C. C., Ponikowski, P., Samani, N. J., van Veldhuisen, D. J., Zannad, F., Zwinderman, A. H., Metra, M., de Boer, R. A., Voors, A. A., Ng, L. L. (2018) Proteomic diversity of high-density lipoprotein explains its association with clinical outcome in patients with heart failure. European Journal of Heart Failure, 20, pp. 260-267. (doi: 10.1002/ejhf.1101)
Ford, T. J., Corcoran, D., Berry, C. (2018) Stable coronary syndromes: pathophysiology, diagnostic advances and therapeutic need. Heart, 104, pp. 284-292. (doi: 10.1136/heartjnl-2017-311446)
Cotter, G., Metra, M., Davison, B. A., Jondeau, G., Cleland, J. G.F., Bourge, R. C., Milo, O., O'Connor, C. M., Parker, J. D., Torre-Amione, G., van Veldhuisen, D. J., Kobrin, I., Rainisio, M., Senger, S., Edwards, C., McMurray, J. J.V., Teerlink, J. R. (2018) Systolic blood pressure reduction during the first 24 h in acute heart failure admission: friend or foe? European Journal of Heart Failure, 20, pp. 317-322. (doi: 10.1002/ejhf.889)
Gallacher, K., Quinn, T. J. (2018) The LAST word on coaching as a stroke intervention? Stroke, 49, pp. 279-280. (doi: 10.1161/STROKEAHA.117.020001)
Stoumpos, S., Lees, J., Welsh, P., Hund, M., Geddes, C. C., Nelson, S. M., Mark, P. B. (2018) The utility of anti-Müllerian hormone in women with chronic kidney disease, on haemodialysis and after kidney transplantation. Reproductive BioMedicine Online, 36, pp. 219-226. (doi: 10.1016/j.rbmo.2017.11.003)
Fertig, B. A., Baillie, G. S. (2018) PDE4-mediated cAMP signalling. Journal of Cardiovascular Development and Disease, 5, (doi: 10.3390/jcdd5010008)
Ouwerkerk, W., Zwinderman, A. H., Ng, L. L., Demissei, B., Hillege, H. L., Zannad, F., van Veldhuisen, D. J., Samani, N. J., Ponikowski, P., Metra, M., ter Maaten, J. M., Lang, C. C., van der Harst, P., Filippatos, G., Dickstein, K., Cleland, J. G., Anker, S. D., Voors, A. A. (2018) Biomarker-guided versus guideline-based treatment of patients with heart failure: results from BIOSTAT-CHF. Journal of the American College of Cardiology, 71, pp. 386-398. (doi: 10.1016/j.jacc.2017.11.041)
Feldman, T., Mauri, L., Kahwash, R., Litwin, S., Ricciardi, M. J., van der Harst, P., Penicka, M., Fail, P. S., Kaye, D. M., Petrie, M. C., Basuray, A., Hummel, S. L., Forde-McLean, R., Nielsen, C. D., Lilly, S., Massaro, J. M., Burkhoff, D., Shah, S. J. (2018) Transcatheter interatrial shunt device for the treatment of heart failure with preserved ejection fraction (REDUCE LAP-HF I [Reduce Elevated Left Atrial Pressure in Patients With Heart Failure]): A phase 2, randomized, sham-controlled trial. Circulation, 137, pp. 364-375. (doi: 10.1161/CIRCULATIONAHA.117.032094)
Williams, J. J.L., Al-Otaiq, N., Mullen, W., Burchmore, R., Liu, L., Baillie, G. S., Schaper, F., Pilch, P. F., Palmer, T. M. (2018) Interaction of suppressor of cytokine signalling 3 with cavin-1 links SOCS3 function and cavin-1 stability. Nature Communications, 9, (doi: 10.1038/s41467-017-02585-y)
Cleland, J. G.F., Flather, M. D., Altman, D. G., Kotecha, D. (2018) Reply: an incomplete story. Journal of the American College of Cardiology, 71, pp. 105. (doi: 10.1016/j.jacc.2017.10.078)
McCarroll, C. S. et al. (2018) Runx1 deficiency protects against adverse cardiac remodeling after myocardial infarction. Circulation, 137, pp. 57-70. (doi: 10.1161/CIRCULATIONAHA.117.028911)
Cleland, J. G.F., Bunting, K. V., Flather, M. D., Altman, D. G., Holmes, J., Coats, A. J.S., Manzano, L., McMurray, J. J.V., Ruschitzka, F., van Veldhuisen, D. J., von Lueder, T. G., Böhm, M., Andersson, B., Kjekshus, J., Packer, M., Rigby, A. S., Rosano, G., Wedel, H., Hjalmarson, Å., Wikstrand, J., Kotecha, D. (2018) Beta-blockers for heart failure with reduced, mid-range, and preserved ejection fraction: an individual patient-level analysis of double-blind randomized trials. European Heart Journal, 39, pp. 26-35. (doi: 10.1093/eurheartj/ehx564)
Rodrigues, A. L., Brescia, M., Kolshinski, A., Moreira, T. H., Cameron, R. T., Baillie, G., Beirão, P. S.L., Zaccollo, M., Cruz, J. S. (2018) Increase in Ca2+ current by sustained cAMP levels enhances proliferation rate in GH3 cells. Life Sciences, 192, pp. 144-150. (doi: 10.1016/j.lfs.2017.11.040)
Masip, J., Peacock, W. F., Price, S., Cullen, L., Martin-Sanchez, F. J., Seferovic, P., Maisel, A. S., Miro, O., Filippatos, G., Vrints, C., Christ, M., Cowie, M., Platz, E., McMurray, J., DiSomma, S., Zeymer, U., Bueno, H., Gale, C. P., Lettino, M., Tavares, M., Ruschitzka, F., Mebazaa, A., Harjola, V.-P., Mueller, C. (2018) Indications and practical approach to non-invasive ventilation in acute heart failure. European Heart Journal, 39, pp. 17-25. (doi: 10.1093/eurheartj/ehx580)
Kristensen, S. L., Mogensen, U. M., Tarnesby, G., Gimpelewicz, C. R., Ali, M. A., Shao, Q., Chiang, Y., Jhund, P. S., Abraham, W. T., Dickstein, K., McMurray, J. J.V., Køber, L. (2018) Aliskiren alone or in combination with enalapril vs. enalapril among patients with chronic heart failure with and without diabetes: a subgroup analysis from the ATMOSPHERE trial. European Journal of Heart Failure, 20, pp. 136-147. (doi: 10.1002/ejhf.896)
Pellicori, P., Urbinati, A., Zhang, J., Joseph, A. C., Costanzo, P., Lukaschuk, E., Capucci, A., Cleland, J. G.F., Clark, A. L. (2018) Clinical and prognostic relationships of pulmonary artery to aorta diameter ratio in patients with heart failure: a cardiac magnetic resonance imaging study. Clinical Cardiology, 41, pp. 20-27. (doi: 10.1002/clc.22840)
Patel, N., Hellmuth, C., Uhl, O., Godfrey, K., Briley, A., Welsh, P., Pasupathy, D., Seed, P., Koletzko, B., Poston, L. (2018) Cord metabolic profiles In obese pregnant women; insights into offspring growth and body composition. Journal of Clinical Endocrinology and Metabolism, 103, pp. 346-355. (doi: 10.1210/jc.2017-00876)
McMurray, J. J.V., Ponikowski, P., Bolli, G. B., Lukashevich, V., Kozlovski, P., Kothny, W., Lewsey, J. D., Krum, H. (2018) Effects of vildagliptin on ventricular function in patients with type 2 diabetes mellitus and heart failure: a randomized placebo-controlled trial. JACC: Heart Failure, 6, pp. 8-17. (doi: 10.1016/j.jchf.2017.08.004)
Arba, F., Quinn, T. J., Hankey, G. J., Lees, K. R., Wardlaw, J. M., Ali, M., Inzitari, D. (2018) Enlarged perivascular spaces and cognitive impairment after stroke and transient ischemic attack. International Journal of Stroke, 13, pp. 47-56. (doi: 10.1177/1747493016666091)
Rørth, R., Fosbøl, E. L., Mogensen, U. M., Kragholm, K., Jhund, P. S., Petrie, M. C., Schou, M., Gislason, G. H., McMurray, J. J.V., Torp-Pedersen, C., Køber, L., Kristensen, S. L. (2018) Evidence based therapy and its association with workforce detachment following first hospitalization for heart failure. JACC: Heart Failure, 6, pp. 41-48. (doi: 10.1016/j.jchf.2017.09.019)
Beggs, S. A.S., Jhund, P. S., Jackson, C. E., McMurray, J. J.V., Gardner, R. S. (2018) Non-ischaemic cardiomyopathy, sudden death and implantable defibrillators: a review and meta-analysis. Heart, 104, pp. 144-150. (doi: 10.1136/heartjnl-2016-310850)
Burton, J. K., Ferguson, E. E.C., Barugh, A. J., Walesby, K. E., MacLullich, A. M.J., Shenkin, S. D., Quinn, T. J. (2018) Predicting discharge to institutional long-term care after stroke: a systematic review and metaanalysis. Journal of the American Geriatrics Society, 66, pp. 161-169. (doi: 10.1111/jgs.15101)
Maznyczka, A. M., McCartney, P., Berry, C. (2018) Reference invasive tests of microvascular injury in myocardial infarction. BMJ Open, 104, pp. 90-92. (doi: 10.1136/heartjnl-2017-311695)
Lee, M. M.Y. et al. (2018) Routine Non-invasive vs Invasive Management in Patients With Prior CABG With a NSTE-ACS: a Randomised Controlled Trial. (doi: 10.1136/heartjnl-2018-BCIS.9)
Quinn, T. J. (2018) Stroke literature synopses: clinical science. Stroke, 49, pp. e5-e6. (doi: 10.1161/STROKEAHA.117.019655)
Taylor-Rowan, M. et al. (2018) Assessing the psychometric properties of the his "Think Frailty" tool. Age and Ageing, 47, pp. iii20-iii23. (doi: 10.1093/ageing/afy127.02)
Souteyrand, G., Valladier, M., Amabile, N., Derimay, F., Harbaoui, B., Leddet, P., Barnay, P., Malcles, G., Mulliez, A., Berry, C., Eschalier, R., Combaret, N., Motreff, P. (2018) Diagnosis and management of spontaneously recanalized coronary thrombus guided by optical coherence tomography ― lessons from the French “Lotus Root” registry ― Circulation Journal, 82, pp. 783-790. (doi: 10.1253/circj.cj-17-0810)
Chuaiphichai, S., Rashbrook, V. S., Hale, A. B., Trelfa, L., Patel, J., McNeill, E., Lygate, C. A., Channon, K. M., Douglas, G. (2018) Endothelial cell tetrahydrobiopterin modulates sensitivity to ang (angiotensin) II–induced vascular remodeling, blood pressure, and abdominal aortic aneurysm. Hypertension, 72, pp. 128-138. (doi: 10.1161/HYPERTENSIONAHA.118.11144)
Yalla, K., Elliott, C., Day, J.P., Findlay, J., Barratt, S., Hughes, Z.A., Wilson, L., Whiteley, E., Popiolek, M., Li, Y., Dunlop, J., Killick, R., Adams, D.R., Brandon, N.J., Houslay, M.D., Hao, B., Baillie, G.S. (2018) FBXW7 regulates DISC1 stability via the ubiquitin-proteosome system. Molecular Psychiatry, 23, pp. 1278-1286. (doi: 10.1038/mp.2017.138)
Howie, J., Wypijewski, K. J., Plain, F., Tulloch, L. B., Fraser, N. J., Fuller, W. (2018) Greasing the wheels or a spanner in the works? Regulation of the cardiac sodium pump by palmitoylation. Critical Reviews in Biochemistry and Molecular Biology, 53, pp. 175-191. (doi: 10.1080/10409238.2018.1432560)
Lachaud, Q., MacQuaide, N., Burton, F., Smith, G. (2018) High-throughput study of rabbit ventricle action potential populations in MI model. Biophysical Journal, 114, pp. 625A. (doi: 10.1016/j.bpj.2017.11.3377)
Berry, C., Carberry, J., Mangion, K. (2018) How to mend a broken heart? JACC: Cardiovascular Imaging, 11, pp. 420-422. (doi: 10.1016/j.jcmg.2017.02.017)
McAllister, D. A., Read, S., Kerssens, J., Livingstone, S., McGurnaghan, S., Jhund, P., Petrie, J., Sattar, N., Fischbacher, C., Kristensen, S. L., McMurray, J., Colhoun, H. M., Wild, S. (2018) Incidence of hospitalisation for heart failure and case-fatality among 3.25 million people with and without diabetes. Circulation, 138, pp. 2774-2785. (doi: 10.1161/CIRCULATIONAHA.118.034986)
Ioannou, A., Carin-Levy, G., Cheyne, J. D., Clarke, D., Cowey, E., Fallon, M., Morton, S., Klinkhamer, L., Kyriakou, G., Fleetwood-Walker, S., Quinn, T., Rush, R., Sande, T., Smith, M., Whalley-Sibley, H., Woodfield, R., Mead, G. (2018) Incidence, types and nature of post-stroke pain: systematic review of literature and meta-analysis [Protocol]
Rørth, R., Fosbøl, E. L., Kragholm, K., Mogensen, U. M., Jhund, P. S., Petrie, M. C., Torp-Pedersen, C., Gislason, G. H., McMurray, J. J.V., Køber, L., Kristensen, S. L. (2018) Initiation of domiciliary care and nursing home admission following first hospitalization for heart failure: a nationwide cohort study. Clinical Epidemiology, 10, pp. 917-930. (doi: 10.2147/CLEP.S164795)
Macdougall, I. C., White, C., Anker, S. D., Bhandari, S., Farrington, K., Kalra, P. A., McMurray, J. J.V., Murray, H., Steenkamp, R., Tomson, C. R.V., Wheeler, D. C., Winearls, C. G., Ford, I. (2018) Randomized trial comparing proactive, high-dose versus reactive, low-dose intravenous iron supplementation in hemodialysis (PIVOTAL): study design and baseline data. American Journal of Nephrology, 48, pp. 260-268. (doi: 10.1159/000493551)
Kraus, W. E., Yates, T., Tuomilehto, J., Sun, J.-L., Thomas, L., McMurray, J. J.V., Bethel, M. A., Holman, R. R. (2018) Relationship between baseline physical activity assessed by pedometer count and new-onset diabetes in the NAVIGATOR trial. BMJ Open Diabetes Research and Care, 6, (doi: 10.1136/bmjdrc-2018-000523)
Seferovic, J. P., Bentley-Lewis, R., Claggett, B., Diaz, R., Gerstein, H. C., Køber, L. V., Lawson, F. C., Lewis, E. F., Maggioni, A. P., McMurray, J. J.V., Probstfield, J. L., Riddle, M. C., Solomon, S. D., Tardif, J.-C., Pfeffer, M. A. (2018) Retinopathy, neuropathy, and subsequent cardiovascular events in patients with type 2 diabetes and acute coronary syndrome in the ELIXA: the importance of disease duration. Journal of Diabetes Research, 2018, (doi: 10.1155/2018/1631263)
Verma, S., McMurray, J. J.V. (2018) SGLT2 inhibitors and mechanisms of cardiovascular benefit: a state-of-the-art review. Diabetologia, 61, pp. 2108-2117. (doi: 10.1007/s00125-018-4670-7)
Layland, J., Tong, D., Lee, M., Berry, C. (2018) ST and T-Wave Abnormality as Footprint of Myocardial Oedema in Non–ST-Elevation Myocardial Infarction. (doi: 10.1016/j.hlc.2018.06.515)
Bouabdallaoui, N. et al. (2018) Society of Thoracic Surgeons risk score and EuroSCORE-2 appropriately assess 30-day postoperative mortality in the STICH trial and a contemporary cohort of patients with left ventricular dysfunction undergoing surgical revascularization. Circulation: Heart Failure, 11, (doi: 10.1161/circheartfailure.118.005531)
Delles, C., Carrick, E., Graham, D., Nicklin, S. A. (2018) Utilising proteomics to understand and define hypertension: where are we and where do we go? Expert Review of Proteomics, 15, pp. 581-592. (doi: 10.1080/14789450.2018.1493927)
2017
Avtaar Singh, S. S., Das De, S., Spadaccio, C., Berry, C., Al-Attar, N. (2017) An overview of different methods of myocardial protection currently employed peri-transplantation. Vessel Plus, 1, pp. 213-229. (doi: 10.20517/2574-1209.2017.26)
Van't Veer, M., Pijls, N. H.J., Hennigan, B., Watkins, S., Ali, Z. A., De Bruyne, B., Zimmermann, F. M., van Nunen, L. X., Barbato, E., Berry, C., Oldroyd, K. G. (2017) Comparison of different diastolic resting indexes to iFR: are they all equal? Journal of the American College of Cardiology, 70, pp. 3088-3096. (doi: 10.1016/j.jacc.2017.10.066)
Ford, T. J., Berry, C., De Bruyne, B., Yong, A. C.S., Barlis, P., Fearon, W. F., Ng, M. K.C. (2017) Physiological predictors of acute coronary syndromes: emerging insights from the plaque to the vulnerable patient. JACC: Cardiovascular Interventions, 10, pp. 2539-2547. (doi: 10.1016/j.jcin.2017.08.059)
Logie, L., Van Aalten, L., Knebel, A., Force, T., Hastie, C. J., MacLauchlan, H., Campbell, D. G., Gourlay, R., Prescott, A., Davidson, J., Fuller, W., Sutherland, C. (2017) Rab-GTPase binding effector protein 2 (RABEP2) is a primed substrate for Glycogen Synthase kinase-3 (GSK3) Scientific Reports, 7, (doi: 10.1038/s41598-017-17087-6)
Berry, C., McClure, J. D., Oldroyd, K. G. (2017) Meta-analysis of death and myocardial infarction in the DEFINE-FLAIR and iFR-SWEDEHEART trials: a hypothesis generating note of caution. Circulation, 136, pp. 2389-2391. (doi: 10.1161/CIRCULATIONAHA.117.030430)
Lei, C. L., Wang, K., Clerx, M., Johnstone, R. H., Hortigon-Vinagre, M. P., Zamora, V., Allan, A., Smith, G. L., Gavaghan, D. J., Mirams, G. R., Polonchuk, L. (2017) Tailoring mathematical models to stem-cell derived cardiomyocyte lines can improve predictions of drug-induced changes to their electrophysiology. Frontiers in Physiology, 8, (doi: 10.3389/fphys.2017.00986)
Duncan, G., Firth, K., George, V., Hoang, M. D., Staniforth, A., Smith, G., Denning, C. (2017) Drug-mediated shortening of action potentials in LQTS2 human induced pluripotent stem cell-derived cardiomyocytes. Stem Cells and Development, 26, pp. 1695-1705. (doi: 10.1089/scd.2017.0172)
Celis-Morales, C. A., Petermann, F., Hui, L., Lyall, D. M., Iliodromiti, S., McLaren, J., Anderson, J., Welsh, P., Mackay, D. F., Pell, J. P., Sattar, N., Gill, J. M.R., Gray, S. R. (2017) Associations between diabetes and both cardiovascular disease and all-cause mortality are modified by grip strength: evidence from UK Biobank, a prospective population-based cohort study. Diabetes Care, 40, pp. 1710-1718. (doi: 10.2337/dc17-0921)
Kaye, D. M., Silvestry, F. E., Gustafsson, F., Cleland, J. G., van Veldhuisen, D. J., Ponikowski, P., Komtebedde, J., Nanayakkara, S., Burkhoff, D., Shah, S. J. (2017) Impact of atrial fibrillation on rest and exercise haemodynamics in heart failure with mid-range and preserved ejection fraction. European Journal of Heart Failure, 19, pp. 1690-1697. (doi: 10.1002/ejhf.930)
Hilfiker-Kleiner, D., Haghikia, A., Masuko, D., Nonhoff, J., Held, D., Libhaber, E., Petrie, M. C., Walker, N. L., Podewski, E., Berliner, D., Bauersachs, J., Sliwa, K. (2017) Outcome of subsequent pregnancies in patients with a history of peripartum cardiomyopathy. European Journal of Heart Failure, 19, pp. 1723-1728. (doi: 10.1002/ejhf.808)
Basole, C. P., Nguyen, R. K., Lamothe, K., Vang, A., Clark, R., Baillie, G. S., Epstein, P. M., Brocke, S. (2017) PDE8 controls CD4(+) T cell motility through the PDE8A-Raf-1 kinase signaling complex. Cellular Signalling, 40, pp. 62-72. (doi: 10.1016/j.cellsig.2017.08.007)
Carberry, J., Carrick, D., Haig, C., Ahmed, N., Mordi, I., McEntegart, M., Petrie, M. C., Eteiba, H., Hood, S., Watkins, S., Lindsay, M., Davie, A., Mahrous, A., Ford, I., Sattar, N., Welsh, P., Radjenovic, A., Oldroyd, K. G., Berry, C. (2017) Persistence of infarct zone T2 hyperintensity at 6 months after acute ST-elevation myocardial infarction: incidence, pathophysiology and prognostic implications. Circulation: Cardiovascular Imaging, 10, (doi: 10.1161/CIRCIMAGING.117.006586)
Kristensen, S. L., Jhund, P. S., Lee, M. M.Y., Køber, L., Solomon, S. D., Granger, C. B., Yusuf, S., Pfeffer, M. A., Swedberg, K., McMurray, J. J.V. (2017) Prevalence of prediabetes and undiagnosed diabetes in patients with HFpEF and HFrEF and associated clinical outcomes. Cardiovascular Drugs and Therapy, 31, pp. 545-549. (doi: 10.1007/s10557-017-6754-x)
Senni, M., McMurray, J. J.V., Wachter, R., McIntyre, H. F., Anand, I. S., Duino, V., Sarkar, A., Shi, V., Charney, A. (2017) Impact of systolic blood pressure on the safety and tolerability of initiating and up-titrating sacubitril/valsartan in patients with heart failure and reduced ejection fraction: insights from the TITRATION study. European Journal of Heart Failure, 20, pp. 491-500. (doi: 10.1002/ejhf.1054)
Vieira, M. C., White, S. L., Patel, N., Seed, P. T., Briley, A. L., Sandall, J., Welsh, P., Sattar, N., Nelson, S. M., Lawlor, D. A., Poston, L., Pasupathy, D. (2017) Prediction of uncomplicated pregnancies in obese women: a prospective multicentre study. BMC Medicine, 15, (doi: 10.1186/s12916-017-0956-8)
Sartini, C., Whincup, P. H., Wannamethee, S. G., Jefferis, B. J., Lennon, L., Lowe, G. D.O., Welsh, P., Sattar, N., Morris, R. W. (2017) Associations of time of day with cardiovascular disease risk factors measured in older men: results from the British Regional Heart Study. BMJ Open, 7, (doi: 10.1136/bmjopen-2017-018264)
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McGovern, A., Pendlebury, S. T., Mishra, N. k., Fan, Y., Quinn, T. J. (2016) Test accuracy of informant-based cognitive screening tests for diagnosis of dementia and multidomain cognitive impairment in stroke. Stroke, 47, pp. 329-335. (doi: 10.1161/strokeaha.115.011218)
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Mangion, K., Gao, H., Radjenovic, A., Luo, X., Haig, C., Berry, C. (2016) Pixel-tracking derived strain using the GlasgowHeart Method. Journal of Cardiovascular Magnetic Resonance, 18, (doi: 10.1186/1532-429X-18-S1-P9)
Bruno, N., ter Maaten, J. M., Ovchinnikova, E. S., Vegter, E. L., Valente, M. A.E., van der Meer, P., de Boer, R. A., van der Harst, P., Schmitter, D., Metra, M., O'Connor, C. M., Ponikowski, P., Teerlink, J. R., Cotter, G., Davison, B., Cleland, J. G.F., Givertz, M. M., Bloomfield, D. M., Dittrich, H. C., Pinto, Y. M., van Veldhuisen, D. J., Hillege, H. L., Berezikov, E., Voors, A. A. (2016) MicroRNAs relate to early worsening of renal function in patients with acute heart failure. International Journal of Cardiology, 203, pp. 564-569. (doi: 10.1016/j.ijcard.2015.10.217)
Bertrand, L., Whittington, H. J., McAndrew, D. J., Cross, R. L., Neubauer, S., Lygate, C. A. (2016) Protective effect of creatine elevation against ischaemia reperfusion injury is retained in the presence of co-morbidities and during cardioplegia. PLoS ONE, 11, (doi: 10.1371/journal.pone.0146429)
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Zervou, S., Whittington, H. J., Russell, A. J., Lygate, C. A. (2016) Augmentation of creatine in the heart. Mini-Reviews in Medicinal Chemistry, 16, pp. 19-28. (doi: 10.2174/1389557515666150722102151)
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Lygate, C. A. (2016) Energetics in the hypertrophied and failing heart. Elsevier (Academic Press)
Hendry, K., Quinn, T. J., Evans, J., Scortichini, V., Miller, H., Burns, J., Cunnington, A., Stott, D. J. (2016) Evaluation of delirium screening tools in geriatric medical inpatients: a diagnostic test accuracy study. Age and Ageing, 45, pp. 832-837. (doi: 10.1093/ageing/afw130)
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McCallum, J. E., Mackenzie, A. E., Divorty, N., Clarke, C., Delles, C., Milligan, G., Nicklin, S. A. (2016) G protein-coupled receptor 35 mediates human saphenous vein vascular smooth muscle cell migration and endothelial cell proliferation. Journal of Vascular Research, 52, pp. 383-395. (doi: 10.1159/000444754)
Kristensen, S. L. et al. (2016) Geographic variations in the PARADIGM-HF heart failure trial. European Heart Journal, 37, pp. 3167-3174. (doi: 10.1093/eurheartj/ehw226)
Corcoran, D., Berry, C. (2016) How to measure myocardial infarct size by cardiac magnetic resonance imaging. Heart and Metabolism, 70, pp. 14-18.
Nadruz, W., Claggett, B. L., McMurray, J. J., Packer, M., Zile, M. R., Rouleau, J. l., Desai, A. S., Swedberg, K., Lefkowitz, M., Shi, V. C., Prescott, M. F., Solomon, S. D. (2016) Impact of Body Mass Index on the Accuracy of N-Terminal Pro-Brain Natriuretic Peptide and Brain Natriuretic Peptide for Predicting Outcomes in Patients With Chronic Heart Failure and Reduced Ejection Fraction: Insights From the PARADIGM-HF Study (Prospective Comparison of ARNI With ACEI to Determine Impact on Global Mortality and Morbidity in Heart Failure Trial) Circulation, 134, pp. 1785-1787. (doi: 10.1161/CIRCULATIONAHA.116.024976)
Mangion, K., Carrick, D., Hennigan, B. W., Payne, A. R., McClure, J., Mason, M., Das, R., Wilson, R., Edwards, R. J., Petrie, M. C., McEntegart, M., Eteiba, H., Oldroyd, K. G., Berry, C. (2016) Infarct size and left ventricular remodelling after preventive percutaneous coronary intervention. Heart, 102, pp. 1980-1987. (doi: 10.1136/heartjnl-2015-308660)
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Emdin, C. A., Conrad, N., Kiran, A., Salimi-Khorshidi, G., Woodward, M., Anderson, S. G., Mohseni, H., Dargie, H. J., Hardman, S. M.C., McDonagh, T., McMurray, J. J.V., Cleland, J. G.F., Rahimi, K. (2016) Variation in hospital performance for heart failure management in the National Heart Failure Audit for England and Wales. Heart, 103, pp. 55-62. (doi: 10.1136/heartjnl-2016-309706)
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2015
Cameron, A. C., Touyz, R. M., Lang, N. N. (2015) Vascular complications of cancer chemotherapy. Canadian Journal of Cardiology, 32, pp. 852-862. (doi: 10.1016/j.cjca.2015.12.023)
Cannon, J. A., McKean, A. R., Jhund, P. S., McMurray, J. J.V. (2015) What can we learn from RELAX-AHF compared to previous AHF trials and what does the future hold? Open Heart, 2, (doi: 10.1136/openhrt-2015-000283)
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Pocock, S. J., McMurray, J. J.V., Collier, T. J. (2015) Statistical controversies in reporting of clinical trials: part 2 of a 4-part series on statistics for clinical trials. Journal of the American College of Cardiology, 66, pp. 2648-62. (doi: 10.1016/j.jacc.2015.10.023)
Pocock, S. J., McMurray, J. J.V., Collier, T. J. (2015) Making sense of statistics in clinical trial reports: Part 1 of a 4-part series on statistics for clinical trials. Journal of the American College of Cardiology, 66, pp. 2536-2549. (doi: 10.1016/j.jacc.2015.10.014)
Claggett, B., Packer, M., McMurray, J. J.V., Swedberg, K., Rouleau, J., Zile, M. R., Jhund, P., Lefkowitz, M., Shi, V., Solomon, S. D. (2015) Estimating the long-term treatment benefits of Sacubitril–Valsartan. New England Journal of Medicine, 373, pp. 2289-2290. (doi: 10.1056/NEJMc1509753)
Gheorghiade, M., Greene, S. J., Butler, J., Filippatos, G., Lam, C. S. P., Maggioni, A. P., Ponikowski, P., Shah, S. J., Solomon, S. D., Kraigher-Krainer, E., Samano, E. T., Müller, K., Roessig, L., Pieske, B., McMurray, J., for the SOCRATES-REDUCED Investigators and Coordinators, . (2015) Effect of vericiguat, a soluble guanylate cyclase stimulator, on natriuretic peptide levels in patients with worsening chronic heart failure and reduced ejection fraction. JAMA: Journal of the American Medical Association, 314, pp. 2251-2262. (doi: 10.1001/jama.2015.15734)
Berry, C., Corcoran, D., Hennigan, B., Watkins, S., Layland, J., Oldroyd, K. G. (2015) Fractional flow reserve-guided management in stable coronary disease and acute myocardial infarction: recent developments. European Heart Journal, 36, pp. 3155-3164. (doi: 10.1093/eurheartj/ehv206)
Wilson, C., Kerr, D., Noel-Storr, A., Quinn, T. (2015) Associations with publication and assessing publication bias in dementia diagnostic test accuracy studies. International Journal of Geriatric Psychiatry, 30, pp. 1250-1256. (doi: 10.1002/gps.4283)
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McMurray, J. J.J.V. (2015) Improving outcomes in heart failure: a personal perspective. European Heart Journal, 36, pp. 3467-3470. (doi: 10.1093/eurheartj/ehv565)
Pfeffer, M. A., Claggett, B., Diaz, R., Dickstein, K., Gerstein, H. C., Køber, L. V., Lawson, F. C., Ping, L., Wei, X., Lewis, E. F., Maggioni, A. P., McMurray, J. J.V., Probstfield, J. L., Riddle, M. C., Solomon, S. D., Tardif, J.-C. (2015) Lixisenatide in patients with type 2 diabetes and acute coronary syndrome. New England Journal of Medicine, 373, pp. 2247-2257. (doi: 10.1056/NEJMoa1509225)
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Zinman, B., Wanner, C., Lachin, J. M., Fitchett, D., Bluhmki, E., Hantel, S., Mattheus, M., Devins, T., Johansen, O. E., Woerle, H. J., Broedl, U. C., Inzucchi, S. E., EMPA-REG OUTCOME Investigators, (2015) Empagliflozin, cardiovascular outcomes, and mortality in type 2 diabetes. New England Journal of Medicine, 373, pp. 2117-2128. (doi: 10.1056/NEJMoa1504720)
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Singh, J., McElroy, M., Quinn, T. (2015) Feasibility of recommended cognitive screening tools for older adults in carehomes. Journal of the American Geriatrics Society, 63, pp. 2432-2434. (doi: 10.1111/jgs.13808)
Baillie, G. S. (2015) George Baillie on peptide array, a technique that transformed research on phosphodiesterases. Future Science OA, 1, (doi: 10.4155/fso.15.25)
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Reilly, L., Howie, J., Wypijewski, K., Ashford, M. L. J., Hilgemann, D. W., Fuller, W. (2015) Palmitoylation of the Na/Ca exchanger cytoplasmic loop controls its inactivation and internalization during stress signaling. FASEB Journal, 29, pp. 4532-4543. (doi: 10.1096/fj.15-276493)
Pellicori, P., Joseph, A. C., Zhang, J., Lukaschuk, E., Sherwi, N., Bourantas, C. V., Loh, H., Clark, A. L., Cleland, J. G.F. (2015) The relationship of QRS morphology with cardiac structure and function in patients with heart failure. Clinical Research in Cardiology, 104, pp. 935-945. (doi: 10.1007/s00392-015-0861-0)
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Voors, A. A., Gori, M., Liu, L. C.Y., Claggett, B., Zile, M. R., Pieske, B., McMurray, J. J.V., Packer, M., Shi, V., Lefkowitz, M. P., Solomon, S. D. (2015) Renal effects of the angiotensin receptor neprilysin inhibitor LCZ696 in patients with heart failure and preserved ejection fraction. European Journal of Heart Failure, 17, pp. 510-517. (doi: 10.1002/ejhf.232)
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Sattar, N., Welsh, P., Preiss, D. (2015) The insulin resistance syndrome. John Wiley & Sons, Ltd
Badar, A. A., Brunton, A. P.T., Mahmood, A. H., Dobbin, S., Pozzi, A., McMinn, J. F., Sinclair, A. J.E., Gardner, R. S., Petrie, M. C., Curry, P. A., Al-Attar, N. H.K., Pettit, S. J. (2015) The management of patients with aortic regurgitation and severe left ventricular dysfunction: a systematic review. Expert Review of Cardiovascular Therapy, 13, pp. 915-922. (doi: 10.1586/14779072.2015.1067139)
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PGR Students
- Postgraduate Research Student
- Research title: Palmitoylation and the regulation of the cardiac transient outward current
- Postgraduate Research Student
- Research title: Runx1 and Heart Disease Post-Myocardial Infarction
- Postgraduate Research Student
- Research title: Developing Therapeutic Approaches for Hemorrhagic Stroke
Heart failure describes a set of symptoms and clinical findings that occur when the heart fails to pump as well as it should. There are many reasons why the heart may not pump properly including weakness and/or stiffness of the heart muscle, narrowed or leaking valves and abnormal heart rhythms. The commonest cause is narrowing of the arteries of the heart and heart attacks. Therefore, heart failure is a very common condition. It is one of the most common causes of hospitalisation in patients over 65 years and so is an extremely costly condition for health services around the world. Heart failure can be a deadly condition, and the life expectancy of patients with heart failure is as poor as patients with some of the most common types of cancer.
Our aim is to understand this condition and help develop effective treatments for heart failure. Our researchers have been involved in many of the landmark trials of drugs and devices to treat heart failure.
Specific areas covered:
- Clinical trials in heart failure
- Epidemiology of heart failure