2024

Geldof, J. et al. (2024) Prophylactic versus endoscopy-driven treatment of Crohn's postoperative recurrence: a retrospective, multicentric, European study [PORCSE Study]. Journal of Crohn's and Colitis, 18(8), pp. 1202-1214. (doi: 10.1093/ecco-jcc/jjae011) (PMID:38243807)

Baxter, M. et al. (2024) An investigation of the clinical impact and therapeutic relevance of a DNA damage immune response (DDIR) signature in patients with advanced gastroesophageal adenocarcinoma. ESMO Open, 9(5), 103450. (doi: 10.1016/j.esmoop.2024.103450) (PMID:38744099) (PMCID:PMC11108838)

2023

Porter, R. J. , Din, S., Bankhead, P., Oniscu, A. and Arends, M. J. (2023) QuPath Algorithm Accurately Identifies MLH1-Deficient Inflammatory Bowel Disease-Associated Colorectal Cancers in a Tissue Microarray. Diagnostics, 13(11), 1890. (doi: 10.3390/diagnostics13111890) (PMID:37296742) (PMCID:PMC10253133)

Porter, R. J. et al. (2023) Subcellular epithelial HMGB1 expression is associated with colorectal neoplastic progression, male sex, mismatch repair protein expression, lymph node positivity, and an ‘immune cold’ phenotype associated with poor survival. Cancers, 15(6), 1865. (doi: 10.3390/cancers15061865) (PMID:36980751) (PMCID:PMC10047220)

2022

Porter, R. J. , McKinlay, A. W. and Metcalfe, E. L. (2022) Endoscopically placed venting gastrostomy can be a safe and effective palliative intervention in benign and malignant gastrointestinal obstruction. Frontline Gastroenterology, 13(4), pp. 309-315. (doi: 10.1136/flgastro-2021-101930) (PMID:35722598) (PMCID:PMC9186026)

Halliday, G., Porter, R. J. , Black, C. J., Arends, M. J. and Din, S. (2022) c-MET immunohistochemical expression in sporadic and inflammatory bowel disease associated lesions. World Journal of Gastroenterology, 28(13), pp. 1338-1346. (doi: 10.3748/wjg.v28.i13.1338) (PMID:35645542) (PMCID:PMC9099184)

Evans, J. A. et al. (2022) Clonal transitions and phenotypic evolution in Barrett’s Esophagus. Gastroenterology, 162(4), 1197-1209.e13. (doi: 10.1053/j.gastro.2021.12.271) (PMID:34973296) (PMCID:PMC8972067)

Brice, D., Murray, G., Wilson, H., Porter, R. , Berry, S., Durum, S. and McLean, M. (2022) Interleukin-27 regulates the function of the gastrointestinal epithelial barrier in a human tissue-derived organoid model. Biology, 11(3), 427. (doi: 10.3390/biology11030427) (PMID:35336801) (PMCID:PMC8945023)

2021

Porter, R. J. , Arends, M. J.,, Churchhouse, A. M.D. and Din, S. (2021) Inflammatory bowel disease-associated colorectal cancer: translational risks from mechanisms to medicines. Journal of Crohn's and Colitis, 15(12), pp. 2131-2141. (doi: 10.1093/ecco-jcc/jjab102) (PMID:34111282) (PMCID:PMC8684457)

Porter, R. J. , Murray, G. I., Alnabulsi, A., Humphries, M. P., James, J. A., Salto-Tellez, M., Craig, S. G., Wang, J. M., Yoshimura, T. and McLean, M. H. (2021) Colonic epithelial cathelicidin (LL-37) expression intensity is associated with progression of colorectal cancer and presence of CD8+ T cell infiltrate: LL-37 expression in colorectal cancer. Journal of Pathology: Clinical Research, 7(5), pp. 495-506. (doi: 10.1002/cjp2.222) (PMID:33988317) (PMCID:PMC8363930)

Porter, R. J./ , Smith, K. J., Ho, G.-T. and Gwyer Findlay, E. (2021) Immunofluorescence on FFPE tissue sections from inflamed and non-inflamed human gut. [Protocols]

Squires, C., Porter, R. J. and Ward, B. M. (2021) Lessons from recent medical history: an obsolete anti-reflux device in an older patient with variable gastrointestinal symptoms. Age and Ageing, 50(4), pp. 1426-1427. (doi: 10.1093/ageing/afab089) (PMID:34038518)

2020

Porter, R. , Murray, G. I. and McLean, M. H. (2020) Current concepts in tumour-derived organoids. British Journal of Cancer, 123, pp. 1209-1218. (doi: 10.1038/s41416-020-0993-5) (PMID:32728094) (PMCID:PMC7555542)

Porter, R. J. , Kalla, R. and Ho, G.-T. (2020) Ulcerative colitis: Recent advances in the understanding of disease pathogenesis. F1000Research, 9, 294. (doi: 10.12688/f1000research.20805.1) (PMID:32399194) (PMCID:PMC7194476)

Porter, R. J. , Murray, G. I., Brice, D. P., Petty, R. D. and McLean, M. H. (2020) Novel biomarkers for risk stratification of Barrett’s oesophagus associated neoplastic progression–epithelial HMGB1 expression and stromal lymphocytic phenotype. British Journal of Cancer, 122, pp. 545-554. (doi: 10.1038/s41416-019-0685-1) (PMID:31831860) (PMCID:PMC7028982)

2019

Porter, R. J. , McKinlay, A. W. and Metcalfe, E. L. (2019) Gastropexy can be as safe as conventional percutaneous endoscopic gastrostomy (PEG), and biomarkers do not predict short-term or long-term outcomes: a 7-year follow-up audit. Frontline Gastroenterology, 11(5), pp. 364-370. (doi: 10.1136/flgastro-2019-101306) (PMID:32884630) (PMCID:PMC7447287)

2018

Porter, R. J. , Andrews, C., Brice, D. P., Durum, S. K. and McLean, M. H. (2018) Can we target endogenous anti-inflammatory responses as a therapeutic strategy for inflammatory bowel disease? Inflammatory Bowel Diseases, 24(10), pp. 2123-2134. (doi: 10.1093/ibd/izy230) (PMID:30020451) (PMCID:PMC6140439)

Cramer, S. D. et al. (2018) Mutant IL-7Rα and mutant NRas are sufficient to induce murine T cell acute lymphoblastic leukemia. Leukemia, 32, pp. 1795-1882. (doi: 10.1038/s41375-017-0001-0) (PMID:29535426) (PMCID:PMC7984718)

2015

Steele, C. et al. (2015) CXCR2 inhibition suppresses acute and chronic pancreatic inflammation. Journal of Pathology, 237(1), pp. 85-97. (doi: 10.1002/path.4555) (PMID:25950520)

Articles

Geldof, J. et al. (2024) Prophylactic versus endoscopy-driven treatment of Crohn's postoperative recurrence: a retrospective, multicentric, European study [PORCSE Study]. Journal of Crohn's and Colitis, 18(8), pp. 1202-1214. (doi: 10.1093/ecco-jcc/jjae011) (PMID:38243807)

Baxter, M. et al. (2024) An investigation of the clinical impact and therapeutic relevance of a DNA damage immune response (DDIR) signature in patients with advanced gastroesophageal adenocarcinoma. ESMO Open, 9(5), 103450. (doi: 10.1016/j.esmoop.2024.103450) (PMID:38744099) (PMCID:PMC11108838)

Porter, R. J. , Din, S., Bankhead, P., Oniscu, A. and Arends, M. J. (2023) QuPath Algorithm Accurately Identifies MLH1-Deficient Inflammatory Bowel Disease-Associated Colorectal Cancers in a Tissue Microarray. Diagnostics, 13(11), 1890. (doi: 10.3390/diagnostics13111890) (PMID:37296742) (PMCID:PMC10253133)

Porter, R. J. et al. (2023) Subcellular epithelial HMGB1 expression is associated with colorectal neoplastic progression, male sex, mismatch repair protein expression, lymph node positivity, and an ‘immune cold’ phenotype associated with poor survival. Cancers, 15(6), 1865. (doi: 10.3390/cancers15061865) (PMID:36980751) (PMCID:PMC10047220)

Porter, R. J. , McKinlay, A. W. and Metcalfe, E. L. (2022) Endoscopically placed venting gastrostomy can be a safe and effective palliative intervention in benign and malignant gastrointestinal obstruction. Frontline Gastroenterology, 13(4), pp. 309-315. (doi: 10.1136/flgastro-2021-101930) (PMID:35722598) (PMCID:PMC9186026)

Halliday, G., Porter, R. J. , Black, C. J., Arends, M. J. and Din, S. (2022) c-MET immunohistochemical expression in sporadic and inflammatory bowel disease associated lesions. World Journal of Gastroenterology, 28(13), pp. 1338-1346. (doi: 10.3748/wjg.v28.i13.1338) (PMID:35645542) (PMCID:PMC9099184)

Evans, J. A. et al. (2022) Clonal transitions and phenotypic evolution in Barrett’s Esophagus. Gastroenterology, 162(4), 1197-1209.e13. (doi: 10.1053/j.gastro.2021.12.271) (PMID:34973296) (PMCID:PMC8972067)

Brice, D., Murray, G., Wilson, H., Porter, R. , Berry, S., Durum, S. and McLean, M. (2022) Interleukin-27 regulates the function of the gastrointestinal epithelial barrier in a human tissue-derived organoid model. Biology, 11(3), 427. (doi: 10.3390/biology11030427) (PMID:35336801) (PMCID:PMC8945023)

Porter, R. J. , Arends, M. J.,, Churchhouse, A. M.D. and Din, S. (2021) Inflammatory bowel disease-associated colorectal cancer: translational risks from mechanisms to medicines. Journal of Crohn's and Colitis, 15(12), pp. 2131-2141. (doi: 10.1093/ecco-jcc/jjab102) (PMID:34111282) (PMCID:PMC8684457)

Porter, R. J. , Murray, G. I., Alnabulsi, A., Humphries, M. P., James, J. A., Salto-Tellez, M., Craig, S. G., Wang, J. M., Yoshimura, T. and McLean, M. H. (2021) Colonic epithelial cathelicidin (LL-37) expression intensity is associated with progression of colorectal cancer and presence of CD8+ T cell infiltrate: LL-37 expression in colorectal cancer. Journal of Pathology: Clinical Research, 7(5), pp. 495-506. (doi: 10.1002/cjp2.222) (PMID:33988317) (PMCID:PMC8363930)

Squires, C., Porter, R. J. and Ward, B. M. (2021) Lessons from recent medical history: an obsolete anti-reflux device in an older patient with variable gastrointestinal symptoms. Age and Ageing, 50(4), pp. 1426-1427. (doi: 10.1093/ageing/afab089) (PMID:34038518)

Porter, R. , Murray, G. I. and McLean, M. H. (2020) Current concepts in tumour-derived organoids. British Journal of Cancer, 123, pp. 1209-1218. (doi: 10.1038/s41416-020-0993-5) (PMID:32728094) (PMCID:PMC7555542)

Porter, R. J. , Kalla, R. and Ho, G.-T. (2020) Ulcerative colitis: Recent advances in the understanding of disease pathogenesis. F1000Research, 9, 294. (doi: 10.12688/f1000research.20805.1) (PMID:32399194) (PMCID:PMC7194476)

Porter, R. J. , Murray, G. I., Brice, D. P., Petty, R. D. and McLean, M. H. (2020) Novel biomarkers for risk stratification of Barrett’s oesophagus associated neoplastic progression–epithelial HMGB1 expression and stromal lymphocytic phenotype. British Journal of Cancer, 122, pp. 545-554. (doi: 10.1038/s41416-019-0685-1) (PMID:31831860) (PMCID:PMC7028982)

Porter, R. J. , McKinlay, A. W. and Metcalfe, E. L. (2019) Gastropexy can be as safe as conventional percutaneous endoscopic gastrostomy (PEG), and biomarkers do not predict short-term or long-term outcomes: a 7-year follow-up audit. Frontline Gastroenterology, 11(5), pp. 364-370. (doi: 10.1136/flgastro-2019-101306) (PMID:32884630) (PMCID:PMC7447287)

Porter, R. J. , Andrews, C., Brice, D. P., Durum, S. K. and McLean, M. H. (2018) Can we target endogenous anti-inflammatory responses as a therapeutic strategy for inflammatory bowel disease? Inflammatory Bowel Diseases, 24(10), pp. 2123-2134. (doi: 10.1093/ibd/izy230) (PMID:30020451) (PMCID:PMC6140439)

Cramer, S. D. et al. (2018) Mutant IL-7Rα and mutant NRas are sufficient to induce murine T cell acute lymphoblastic leukemia. Leukemia, 32, pp. 1795-1882. (doi: 10.1038/s41375-017-0001-0) (PMID:29535426) (PMCID:PMC7984718)

Steele, C. et al. (2015) CXCR2 inhibition suppresses acute and chronic pancreatic inflammation. Journal of Pathology, 237(1), pp. 85-97. (doi: 10.1002/path.4555) (PMID:25950520)

Protocols

Porter, R. J./ , Smith, K. J., Ho, G.-T. and Gwyer Findlay, E. (2021) Immunofluorescence on FFPE tissue sections from inflamed and non-inflamed human gut. [Protocols]