2024

Vens, C. et al. (2024) A joint physics and radiobiology DREAM team vision - towards better response prediction models to advance radiotherapy. Radiotherapy and Oncology, 196, 110277. (doi: 10.1016/j.radonc.2024.110277) (PMID:38670264)

Derby, S. et al. (2024) Concurrent olaparib and radiotherapy in elderly patients with newly diagnosed glioblastoma: the phase I dose escalation PARADIGM trial. International Journal of Radiation Oncology, Biology, Physics, 118(5), pp. 1371-1378. (doi: 10.1016/j.ijrobp.2024.01.011) (PMID:38211641)

Derby, S. et al. (2024) Concurrent olaparib and radiation therapy in older patients with newly diagnosed glioblastoma: the phase 1 dose-escalation PARADIGM trial. International Journal of Radiation Oncology, Biology, Physics, 118(5), pp. 1371-1378. (doi: 10.1016/j.ijrobp.2024.01.011) (PMID:38211641)

Derby, S. et al. (2024) Inhibition of ATR opposes glioblastoma invasion through disruption of cytoskeletal networks and integrin internalisation via macropinocytosis. Neuro-Oncology, (doi: 10.1093/neuonc/noad210) (PMID:37936324) (Early Online Publication)

2023

Westerhof, L. M., Noonan, J., Hargrave, K. E., Chimbayo, E. T., Cheng, Z., Purnell, T., Jackson, M. R. , Borcherding, N. and MacLeod, M. K.L. (2023) Multifunctional cytokine production marks influenza A virus specific CD4 T cells with high expression of survival molecules. European Journal of Immunology, 53(11), 2350559. (doi: 10.1002/eji.202350559) (PMID:37490492)

Halstead, S. K. et al. (2023) Serum anti‐GM2 and anti‐GalNAc‐GD1a ganglioside IgG antibodies are biomarkers for immune‐mediated polyneuropathies in cats. Journal of the Peripheral Nervous System, 28(1), pp. 32-40. (doi: 10.1111/jns.12529) (PMID:36573790)

2022

Koessinger, A. L. et al. (2022) Increased apoptotic sensitivity of glioblastoma enables therapeutic targeting by BH3-mimetics. Cell Death and Differentiation, 29(10), pp. 2089-2104. (doi: 10.1038/s41418-022-01001-3) (PMID:35473984) (PMCID:PMC9525582)

Halstead, S.K. et al. (2022) Serum anti-GM2 and anti-GalNAc-GD1a IgG antibodies are biomarkers for acute canine polyradiculoneuritis. Journal of Small Animal Practice, 63(2), pp. 104-112. (doi: 10.1111/jsap.13439) (PMID:34791652)

Jackson, M. R. et al. (2022) Low-dose lung radiotherapy for COVID-19 lung disease: a preclinical efficacy study in a bleomycin model of pneumonitis. International Journal of Radiation Oncology, Biology, Physics, 112(1), pp. 197-211. (doi: 10.1016/j.ijrobp.2021.08.029) (PMID:34478832) (PMCID:PMC8406661)

2021

Bavelaar, B. M. et al. (2021) Oligonucleotide-functionalized gold nanoparticles for synchronous telomerase inhibition, radiosensitization, and delivery of theranostic radionuclides. Molecular Pharmaceutics, 18(10), pp. 3820-3831. (doi: 10.1021/acs.molpharmaceut.1c00442) (PMID:34449222) (PMCID:PMC8493550)

Koessinger, A. L. et al. (2021) Increased apoptotic priming of glioblastoma enables therapeutic targeting by BH3-mimetics. bioRxiv, (doi: 10.1101/2021.06.13.448232)

2020

Jackson, M. R. , Ashton, M., Koessinger, A. L., Dick, C., Verheij, M. and Chalmers, A. J. (2020) Mesothelioma cells depend on the anti-apoptotic protein Bcl-xL for survival and are sensitized to ionizing radiation by BH3-mimetics. International Journal of Radiation Oncology, Biology, Physics, 106(4), pp. 867-877. (doi: 10.1016/j.ijrobp.2019.11.029) (PMID:31786278)

Gomez-Roman, N. , Chong, M. Y., Chahal, S. K., Caragher, S. P., Jackson, M. R. , Stevenson, K. H., Dongre, S. A. and Chalmers, A. J. (2020) Radiation responses of 2D and 3D glioblastoma cells: a novel, 3D-specific radioprotective role of VEGF/Akt signaling through functional activation of NHEJ. Molecular Cancer Therapeutics, 19(2), pp. 575-589. (doi: 10.1158/1535-7163.MCT-18-1320) (PMID:31672763)

2019

Gilbert, H. T. J., Mallikarjun, V., Dobre, O. , Jackson, M. R. , Pedley, R., Gilmore, A. P., Richardson, S. M. and Swift, J. (2019) Nuclear decoupling is part of a rapid protein-level cellular response to high-intensity mechanical loading. Nature Communications, 10, 4149. (doi: 10.1038/s41467-019-11923-1) (PMID:31515493) (PMCID:PMC6742657)

Jackson, M. R. , Bavelaar, B. M., Waghorn, P. A., Gill, M. R., El-Sagheer, A. H., Brown, T., Tarsounas, M. and Vallis, K. A. (2019) Radiolabeled oligonucleotides targeting the RNA subunit of telomerase inhibit telomerase and induce DNA damage in telomerase-positive cancer cells. Cancer Research, 79(18), pp. 4627-4637. (doi: 10.1158/0008-5472.CAN-18-3594) (PMID:31311806)

2017

Waghorn, P. A., Jackson, M. R. , Gouverneur, V. and Vallis, K. A. (2017) Targeting telomerase with radiolabeled inhibitors. European Journal of Medicinal Chemistry, 125, pp. 117-129. (doi: 10.1016/j.ejmech.2016.09.028) (PMID:27657809) (PMCID:PMC5154340)

2016

Cho, I., Jackson, M. R. and Swift, J. (2016) Roles of cross-membrane transport and signaling in the maintenance of cellular homeostasis. Cellular and Molecular Bioengineering, 9(2), pp. 234-246. (doi: 10.1007/s12195-016-0439-6) (PMID:27335609) (PMCID:PMC4893050)

2013

Jackson, M.R. , Falzone, N. and Vallis, K.A. (2013) Advances in anticancer radiopharmaceuticals. Clinical Oncology, 25(10), pp. 604-609. (doi: 10.1016/j.clon.2013.06.004) (PMID:23870756)

Articles

Vens, C. et al. (2024) A joint physics and radiobiology DREAM team vision - towards better response prediction models to advance radiotherapy. Radiotherapy and Oncology, 196, 110277. (doi: 10.1016/j.radonc.2024.110277) (PMID:38670264)

Derby, S. et al. (2024) Concurrent olaparib and radiotherapy in elderly patients with newly diagnosed glioblastoma: the phase I dose escalation PARADIGM trial. International Journal of Radiation Oncology, Biology, Physics, 118(5), pp. 1371-1378. (doi: 10.1016/j.ijrobp.2024.01.011) (PMID:38211641)

Derby, S. et al. (2024) Concurrent olaparib and radiation therapy in older patients with newly diagnosed glioblastoma: the phase 1 dose-escalation PARADIGM trial. International Journal of Radiation Oncology, Biology, Physics, 118(5), pp. 1371-1378. (doi: 10.1016/j.ijrobp.2024.01.011) (PMID:38211641)

Derby, S. et al. (2024) Inhibition of ATR opposes glioblastoma invasion through disruption of cytoskeletal networks and integrin internalisation via macropinocytosis. Neuro-Oncology, (doi: 10.1093/neuonc/noad210) (PMID:37936324) (Early Online Publication)

Westerhof, L. M., Noonan, J., Hargrave, K. E., Chimbayo, E. T., Cheng, Z., Purnell, T., Jackson, M. R. , Borcherding, N. and MacLeod, M. K.L. (2023) Multifunctional cytokine production marks influenza A virus specific CD4 T cells with high expression of survival molecules. European Journal of Immunology, 53(11), 2350559. (doi: 10.1002/eji.202350559) (PMID:37490492)

Halstead, S. K. et al. (2023) Serum anti‐GM2 and anti‐GalNAc‐GD1a ganglioside IgG antibodies are biomarkers for immune‐mediated polyneuropathies in cats. Journal of the Peripheral Nervous System, 28(1), pp. 32-40. (doi: 10.1111/jns.12529) (PMID:36573790)

Koessinger, A. L. et al. (2022) Increased apoptotic sensitivity of glioblastoma enables therapeutic targeting by BH3-mimetics. Cell Death and Differentiation, 29(10), pp. 2089-2104. (doi: 10.1038/s41418-022-01001-3) (PMID:35473984) (PMCID:PMC9525582)

Halstead, S.K. et al. (2022) Serum anti-GM2 and anti-GalNAc-GD1a IgG antibodies are biomarkers for acute canine polyradiculoneuritis. Journal of Small Animal Practice, 63(2), pp. 104-112. (doi: 10.1111/jsap.13439) (PMID:34791652)

Jackson, M. R. et al. (2022) Low-dose lung radiotherapy for COVID-19 lung disease: a preclinical efficacy study in a bleomycin model of pneumonitis. International Journal of Radiation Oncology, Biology, Physics, 112(1), pp. 197-211. (doi: 10.1016/j.ijrobp.2021.08.029) (PMID:34478832) (PMCID:PMC8406661)

Bavelaar, B. M. et al. (2021) Oligonucleotide-functionalized gold nanoparticles for synchronous telomerase inhibition, radiosensitization, and delivery of theranostic radionuclides. Molecular Pharmaceutics, 18(10), pp. 3820-3831. (doi: 10.1021/acs.molpharmaceut.1c00442) (PMID:34449222) (PMCID:PMC8493550)

Koessinger, A. L. et al. (2021) Increased apoptotic priming of glioblastoma enables therapeutic targeting by BH3-mimetics. bioRxiv, (doi: 10.1101/2021.06.13.448232)

Jackson, M. R. , Ashton, M., Koessinger, A. L., Dick, C., Verheij, M. and Chalmers, A. J. (2020) Mesothelioma cells depend on the anti-apoptotic protein Bcl-xL for survival and are sensitized to ionizing radiation by BH3-mimetics. International Journal of Radiation Oncology, Biology, Physics, 106(4), pp. 867-877. (doi: 10.1016/j.ijrobp.2019.11.029) (PMID:31786278)

Gomez-Roman, N. , Chong, M. Y., Chahal, S. K., Caragher, S. P., Jackson, M. R. , Stevenson, K. H., Dongre, S. A. and Chalmers, A. J. (2020) Radiation responses of 2D and 3D glioblastoma cells: a novel, 3D-specific radioprotective role of VEGF/Akt signaling through functional activation of NHEJ. Molecular Cancer Therapeutics, 19(2), pp. 575-589. (doi: 10.1158/1535-7163.MCT-18-1320) (PMID:31672763)

Gilbert, H. T. J., Mallikarjun, V., Dobre, O. , Jackson, M. R. , Pedley, R., Gilmore, A. P., Richardson, S. M. and Swift, J. (2019) Nuclear decoupling is part of a rapid protein-level cellular response to high-intensity mechanical loading. Nature Communications, 10, 4149. (doi: 10.1038/s41467-019-11923-1) (PMID:31515493) (PMCID:PMC6742657)

Jackson, M. R. , Bavelaar, B. M., Waghorn, P. A., Gill, M. R., El-Sagheer, A. H., Brown, T., Tarsounas, M. and Vallis, K. A. (2019) Radiolabeled oligonucleotides targeting the RNA subunit of telomerase inhibit telomerase and induce DNA damage in telomerase-positive cancer cells. Cancer Research, 79(18), pp. 4627-4637. (doi: 10.1158/0008-5472.CAN-18-3594) (PMID:31311806)

Waghorn, P. A., Jackson, M. R. , Gouverneur, V. and Vallis, K. A. (2017) Targeting telomerase with radiolabeled inhibitors. European Journal of Medicinal Chemistry, 125, pp. 117-129. (doi: 10.1016/j.ejmech.2016.09.028) (PMID:27657809) (PMCID:PMC5154340)

Cho, I., Jackson, M. R. and Swift, J. (2016) Roles of cross-membrane transport and signaling in the maintenance of cellular homeostasis. Cellular and Molecular Bioengineering, 9(2), pp. 234-246. (doi: 10.1007/s12195-016-0439-6) (PMID:27335609) (PMCID:PMC4893050)

Jackson, M.R. , Falzone, N. and Vallis, K.A. (2013) Advances in anticancer radiopharmaceuticals. Clinical Oncology, 25(10), pp. 604-609. (doi: 10.1016/j.clon.2013.06.004) (PMID:23870756)