Number of items: 12.
2024
Khalaf, A. et al.
(2024)
Nutrient-sensitizing drug repurposing screen identifies lomerizine as a mitochondrial metabolism inhibitor of chronic myeloid leukemia.
Science Translational Medicine, 16(751),
eadi5336.
(doi: 10.1126/scitranslmed.adi5336)
(PMID:38865484)
Zarou, M. M. et al.
(2024)
Inhibition of mitochondrial folate metabolism drives differentiation through mTORC1-mediated purine sensing.
Nature Communications, 15,
1931.
(doi: 10.1038/s41467-024-46114-0)
(PMID:38431691)
(PMCID:PMC10908830)
Rattigan, K. M.
(2024)
Mini review of metabolism in leukaemia: from complexity to the clinic.
Frontiers in Hematology, 2,
1353994.
(doi: 10.3389/frhem.2023.1353994)
2023
Rattigan, K. M. et al.
(2023)
Arginine dependency is a therapeutically exploitable vulnerability in chronic myeloid leukaemic stem cells.
EMBO Reports, 24,
e56279.
(doi: 10.15252/embr.202256279)
(PMID:37489735)
(PMCID:PMC10561355)
Rattigan, K. M. et al.
(2023)
Pyruvate anaplerosis is a targetable vulnerability in persistent leukaemic stem cells.
Nature Communications, 14,
4634.
(doi: 10.1038/s41467-023-40222-z)
(PMID:37591854)
(PMCID:PMC10435520)
Rattigan, K. M., Zarou, M.-M. and Helgason, G. V.
(2023)
Metabolism in stem cell driven leukaemia: parallels between haematopoiesis and immunity.
Blood, 141(21),
pp. 2553-2565.
(doi: 10.1182/blood.2022018258)
(PMID:36634302)
(PMCID:PMC10646800)
Woodley, K. et al.
(2023)
Mannose metabolism inhibition sensitizes acute myeloid leukaemia cells to therapy by driving ferroptotic cell death.
Nature Communications, 14,
2132.
(doi: 10.1038/s41467-023-37652-0)
(PMID:37059720)
(PMCID:PMC10104861)
2021
Ianniciello, A. et al.
(2021)
ULK1 inhibition promotes oxidative stress–induced differentiation and sensitizes leukemic stem cells to targeted therapy.
Science Translational Medicine, 13(613),
eabd5016.
(doi: 10.1126/scitranslmed.abd5016)
(PMID:34586834)
2020
Rodgers, L. C., Cole, J., Rattigan, K. M., Barrett, M. P. , Kurian, N., McInnes, I. B. and Goodyear, C. S.
(2020)
The rheumatoid synovial environment alters fatty acid metabolism in human monocytes and enhances CCL20 secretion.
Rheumatology, 59(4),
pp. 869-878.
(doi: 10.1093/rheumatology/kez378)
(PMID:31497857)
2018
Ianniciello, A., Rattigan, K. M. and Helgason, G. V.
(2018)
The ins and outs of autophagy and metabolism in hematopoietic and leukemic stem cells: food for thought.
Frontiers in Cell and Developmental Biology, 6,
120.
(doi: 10.3389/fcell.2018.00120)
(PMID:30320108)
(PMCID:PMC6169402)
Steketee, P. C. et al.
(2018)
Benzoxaborole treatment perturbs S-adenosyl-L-methionine metabolism in Trypanosoma brucei.
PLoS Neglected Tropical Diseases, 12(5),
e0006450.
(doi: 10.1371/journal.pntd.0006450)
(PMID:29758036)
(PMCID:PMC5976210)
Rattigan, K. M., Pountain, A. W. , Regnault, C., Achcar, F. , Vincent, I. M. , Goodyear, C. S. and Barrett, M. P.
(2018)
Metabolomic profiling of macrophages determines the discrete metabolomic signature and metabolomic interactome triggered by polarising immune stimuli.
PLoS ONE, 13(3),
e0194126.
(doi: 10.1371/journal.pone.0194126)
(PMID:29538444)
(PMCID:PMC5851634)
This list was generated on Fri Nov 22 12:39:01 2024 GMT.
