Dr Cassie Clarke

  • Honorary Lecturer (School of Cancer Sciences)

CRUK Beatson Institute, Garscube Estate, Switchback Road, Glasgow, G61 1BD

Import to contacts

Biography

2023

BACR Travel Grant – BioCity Symposium: Sculpting Tissues, Cells, Matrix and Forces. Turku, Finland.

The Biochemical Society Travel Grant Award – Fibronectin, Integrins and Related Molecules Gordon Conference. California, USA.

2020

Patent: PCT/GB2020/050532: Invention of designer protein sensor arrays and their application to cancer detection.  Woolfson DN, Dawson WM, Rhys GG, Scott A, Fletcher JM, Wood CW, Clarke CJ and Norman JC. 2020

2019

Metastasis Research Society Meeting Bursary Award – 2nd Joint Conference on Seed and Soil, Mechanisms of Metastasis. Berlin, Germany.

2014

John Paul Career Development Award. CRUK Beatson Institute, Glasgow, UK.

Best PhD student oral presentation, 6th Course on cytoskeleton & cell matrix interactions. Institut Curie, Paris, France.

2011

Pfizer Sandwich Research Recognition Award. Pfizer, Kent, UK.

2010

Individual Performance Award. Pfizer, Kent, UK.

2009

Team Award, The Bronchodilator Research Team. Pfizer, Kent, UK.

Individual Performance Award. Pfizer, Kent, UK.

2008

Young Pharmacologist Bursary Award, British Pharmacological Society. Brighton, UK.

Individual Performance Award. Pfizer, Kent, UK.

2007

University of Glasgow Pontecorvo Award in 4th academic year for best individual performance in Molecular Genetics. Glasgow, UK.

2006

Prize (sponsored by Pfizer) coupled with distinction (sponsored by University of Glasgow) for Best Industrial Placement

High Quality Data & Excellence, Impact Award. Pfizer, Kent, UK.

Undergraduate Prize, UK Bioscience Research and R&D conference. Westminster, London, UK.

2005

University of Glasgow Pontecorvo Award in 3rd academic year for best individual performance in Molecular Genetics. Glasgow, UK.

 

 

Research interests

Understanding immunometabolic mechanisms that facilitate metastasis, and how we can use this information in the context of prevention biology and early detection of cancer.

Publications

List by: Type | Date

Jump to: 2024 | 2020 | 2018 | 2017 | 2016
Number of items: 8.

2024

Laing, A. et al. (2024) Paediatric bone marrow mesenchymal stem cells support acute myeloid leukaemia cell survival and enhance chemoresistance via contact-independent mechanism. British Journal of Haematology, (doi: 10.1111/bjh.19884) (Early Online Publication)

Fetit, R. et al. (2024) Characterising neutrophil subtypes in cancer using scRNA sequencing demonstrates the importance of IL-1β/CXCR2 axis in generation of metastasis specific neutrophils. Cancer Research Communications, 4(2), pp. 588-606. (doi: 10.1158/2767-9764.CRC-23-0319) (PMID:38358352) (PMCID:PMC10903300)

Scott, M. T. et al. (2024) Activating p53 abolishes self-renewal of quiescent leukaemic stem cells in residual CML disease. Nature Communications, 15, 651. (doi: 10.1038/s41467-024-44771-9) (PMID:38246924) (PMCID:PMC10800356)

2020

Kinstrie, R. et al. (2020) CD93 is expressed on chronic myeloid leukemia stem cells and identifies a quiescent population which persists after tyrosine kinase inhibitor therapy. Leukemia, 34(6), pp. 1613-1625. (doi: 10.1038/s41375-019-0684-5) (PMID:31896780) (PMCID:PMC7272220)

2018

Pellicano, F. et al. (2018) Hsa-mir183/EGR1-mediated regulation of E2F1 is required for CML stem/progenitor cell survival. Blood, 131(14), pp. 1532-1544. (doi: 10.1182/blood-2017-05-783845) (PMID:29437554) (PMCID:PMC6027092)

2017

Clarke, C. J. and Holyoake, T. L. (2017) Preclinical approaches in chronic myeloid leukemia: from cells to systems. Experimental Hematology, 47, pp. 13-23. (doi: 10.1016/j.exphem.2016.11.005) (PMID:28017647) (PMCID:5333535)

2016

Birch, J. et al. (2016) The initiator methionine tRNA drives cell migration and invasion leading to increased metastatic potential in melanoma. Biology Open, 5(10), pp. 1371-1379. (doi: 10.1242/bio.019075) (PMID:27543055) (PMCID:PMC5087684)

Clarke, C. J. et al. (2016) The initiator methionine tRNA drives secretion of type II collagen from stromal fibroblasts to promote tumor growth and angiogenesis. Current Biology, 26(6), pp. 755-765. (doi: 10.1016/j.cub.2016.01.045) (PMID:26948875) (PMCID:PMC4819511)

This list was generated on Thu Nov 21 03:20:53 2024 GMT.
Jump to: Articles
Number of items: 8.

Articles

Laing, A. et al. (2024) Paediatric bone marrow mesenchymal stem cells support acute myeloid leukaemia cell survival and enhance chemoresistance via contact-independent mechanism. British Journal of Haematology, (doi: 10.1111/bjh.19884) (Early Online Publication)

Fetit, R. et al. (2024) Characterising neutrophil subtypes in cancer using scRNA sequencing demonstrates the importance of IL-1β/CXCR2 axis in generation of metastasis specific neutrophils. Cancer Research Communications, 4(2), pp. 588-606. (doi: 10.1158/2767-9764.CRC-23-0319) (PMID:38358352) (PMCID:PMC10903300)

Scott, M. T. et al. (2024) Activating p53 abolishes self-renewal of quiescent leukaemic stem cells in residual CML disease. Nature Communications, 15, 651. (doi: 10.1038/s41467-024-44771-9) (PMID:38246924) (PMCID:PMC10800356)

Kinstrie, R. et al. (2020) CD93 is expressed on chronic myeloid leukemia stem cells and identifies a quiescent population which persists after tyrosine kinase inhibitor therapy. Leukemia, 34(6), pp. 1613-1625. (doi: 10.1038/s41375-019-0684-5) (PMID:31896780) (PMCID:PMC7272220)

Pellicano, F. et al. (2018) Hsa-mir183/EGR1-mediated regulation of E2F1 is required for CML stem/progenitor cell survival. Blood, 131(14), pp. 1532-1544. (doi: 10.1182/blood-2017-05-783845) (PMID:29437554) (PMCID:PMC6027092)

Clarke, C. J. and Holyoake, T. L. (2017) Preclinical approaches in chronic myeloid leukemia: from cells to systems. Experimental Hematology, 47, pp. 13-23. (doi: 10.1016/j.exphem.2016.11.005) (PMID:28017647) (PMCID:5333535)

Birch, J. et al. (2016) The initiator methionine tRNA drives cell migration and invasion leading to increased metastatic potential in melanoma. Biology Open, 5(10), pp. 1371-1379. (doi: 10.1242/bio.019075) (PMID:27543055) (PMCID:PMC5087684)

Clarke, C. J. et al. (2016) The initiator methionine tRNA drives secretion of type II collagen from stromal fibroblasts to promote tumor growth and angiogenesis. Current Biology, 26(6), pp. 755-765. (doi: 10.1016/j.cub.2016.01.045) (PMID:26948875) (PMCID:PMC4819511)

This list was generated on Thu Nov 21 03:20:53 2024 GMT.

Cassie Clarke portrait