Ms Angela Ianniciello
- Affiliate (School of Cancer Sciences)
Publications
2024
Zarou, M. M. et al. (2024) Inhibition of mitochondrial folate metabolism drives differentiation through mTORC1-mediated purine sensing. Nature Communications, 15, 1931. (doi: 10.1038/s41467-024-46114-0) (PMID:38431691) (PMCID:PMC10908830)
Dawson, A. et al. (2024) Leukaemia exposure alters the transcriptional profile and function of BCR::ABL1 negative macrophages in the bone marrow niche. Nature Communications, 15, 1090. (doi: 10.1038/s41467-024-45471-0) (PMID:38316788) (PMCID:PMC10844594)
2023
Rattigan, K. M. et al. (2023) Arginine dependency is a therapeutically exploitable vulnerability in chronic myeloid leukaemic stem cells. EMBO Reports, 24, e56279. (doi: 10.15252/embr.202256279) (PMID:37489735) (PMCID:PMC10561355)
Rattigan, K. M. et al. (2023) Pyruvate anaplerosis is a targetable vulnerability in persistent leukaemic stem cells. Nature Communications, 14, 4634. (doi: 10.1038/s41467-023-40222-z) (PMID:37591854) (PMCID:PMC10435520)
2022
Ianniciello, A. and Helgason, G. V. (2022) Targeting ULK1 in cancer stem cells: insight from chronic myeloid leukemia. Autophagy, 18(7), pp. 1734-1736. (doi: 10.1080/15548627.2022.2041152) (PMID:35227175) (PMCID:PMC9298457)
2021
Ianniciello, A. et al. (2021) ULK1 inhibition promotes oxidative stress–induced differentiation and sensitizes leukemic stem cells to targeted therapy. Science Translational Medicine, 13(613), eabd5016. (doi: 10.1126/scitranslmed.abd5016) (PMID:34586834)
Ianniciello, A. and Helgason, G. V. (2021) Autophagy in hematopoiesis and leukemogenesis. In: Rothermel, B. A. and Diwan, A. (eds.) Autophagy in Health and Disease. Second Edition. Academic Press: London, pp. 125-141. ISBN 9780128220030 (doi: 10.1016/B978-0-12-822003-0.00021-8)
2019
Baquero, P. et al. (2019) Targeting quiescent leukemic stem cells using second generation autophagy inhibitors. Leukemia, 33(4), pp. 981-994. (doi: 10.1038/s41375-018-0252-4) (PMID:30185934) (PMCID:PMC6292500)
2018
Ianniciello, A., Rattigan, K. M. and Helgason, G. V. (2018) The ins and outs of autophagy and metabolism in hematopoietic and leukemic stem cells: food for thought. Frontiers in Cell and Developmental Biology, 6, 120. (doi: 10.3389/fcell.2018.00120) (PMID:30320108) (PMCID:PMC6169402)
Articles
Zarou, M. M. et al. (2024) Inhibition of mitochondrial folate metabolism drives differentiation through mTORC1-mediated purine sensing. Nature Communications, 15, 1931. (doi: 10.1038/s41467-024-46114-0) (PMID:38431691) (PMCID:PMC10908830)
Dawson, A. et al. (2024) Leukaemia exposure alters the transcriptional profile and function of BCR::ABL1 negative macrophages in the bone marrow niche. Nature Communications, 15, 1090. (doi: 10.1038/s41467-024-45471-0) (PMID:38316788) (PMCID:PMC10844594)
Rattigan, K. M. et al. (2023) Arginine dependency is a therapeutically exploitable vulnerability in chronic myeloid leukaemic stem cells. EMBO Reports, 24, e56279. (doi: 10.15252/embr.202256279) (PMID:37489735) (PMCID:PMC10561355)
Rattigan, K. M. et al. (2023) Pyruvate anaplerosis is a targetable vulnerability in persistent leukaemic stem cells. Nature Communications, 14, 4634. (doi: 10.1038/s41467-023-40222-z) (PMID:37591854) (PMCID:PMC10435520)
Ianniciello, A. and Helgason, G. V. (2022) Targeting ULK1 in cancer stem cells: insight from chronic myeloid leukemia. Autophagy, 18(7), pp. 1734-1736. (doi: 10.1080/15548627.2022.2041152) (PMID:35227175) (PMCID:PMC9298457)
Ianniciello, A. et al. (2021) ULK1 inhibition promotes oxidative stress–induced differentiation and sensitizes leukemic stem cells to targeted therapy. Science Translational Medicine, 13(613), eabd5016. (doi: 10.1126/scitranslmed.abd5016) (PMID:34586834)
Baquero, P. et al. (2019) Targeting quiescent leukemic stem cells using second generation autophagy inhibitors. Leukemia, 33(4), pp. 981-994. (doi: 10.1038/s41375-018-0252-4) (PMID:30185934) (PMCID:PMC6292500)
Ianniciello, A., Rattigan, K. M. and Helgason, G. V. (2018) The ins and outs of autophagy and metabolism in hematopoietic and leukemic stem cells: food for thought. Frontiers in Cell and Developmental Biology, 6, 120. (doi: 10.3389/fcell.2018.00120) (PMID:30320108) (PMCID:PMC6169402)
Book Sections
Ianniciello, A. and Helgason, G. V. (2021) Autophagy in hematopoiesis and leukemogenesis. In: Rothermel, B. A. and Diwan, A. (eds.) Autophagy in Health and Disease. Second Edition. Academic Press: London, pp. 125-141. ISBN 9780128220030 (doi: 10.1016/B978-0-12-822003-0.00021-8)