Dr les nicolson

Affiliate (School of Biodiversity, One Health & Veterinary Medicine)

email: Lesley.Nicolson@glasgow.ac.uk

McCall Building, Garscube Campus, 464 Bearsden Road, Glasgow, G61 1QH

Research interests

Research interests extend to the application of viruses as gene therapy vectors and vaccines (Morrison et al., 2003) and to the investigation, and potential application of, cytokines in domestic animal species (Hanlon et al. 2001, OÆDonovan et al., 2005). With Professor Iain Morgan we are currently engineering canine adenoviruses (Morrison et al., 2002) as conditionally replicating oncolytic vectors for the potential therapy of canine cancer. In addition, in collaboration with Dr Diane Addie and Dr Stephen Dunham, we are conducting research into feline coronavirus infection in cats (Addie et al. 2003). Our pilot study on equine inflammatory airway disease, with Dr Kris Hughes and Dr Stephen Dunham, has identified a potential role for specific cytokines in this disease and we aim to further investigate the aetiology of this disease.

Research groups

Educational Research & Scholarship

Publications

List by: Type | Date

Jump to: 2018 | 2017 | 2013 | 2011 | 2010 | 2008 | 2005 | 2004 | 2003 | 2002 | 2001

Number of items: 16.

2018

Dunbar, D. et al. (2018) Diagnosis of non-effusive feline infectious peritonitis by reverse transcriptase quantitative PCR from mesenteric lymph node fine-needle aspirates. Journal of Feline Medicine and Surgery, (doi: 10.1177/1098612X18809165) (PMID:30407137)

2017

Terron-Canedo, N., Weir, W. , Nicolson, L., Britton, C. and Nasir, L. (2017) Differential expression of microRNAs in bovine papillomavirus type 1 transformed equine cells. Veterinary and Comparative Oncology, 15(3), pp. 764-774. (doi: 10.1111/vco.12216) (PMID:27039895)

2013

Grosset, A. et al. (2013) Engaging Students in Peerwise: An Innovative Online Learning Approach. 6th Annual University of Glasgow Learning and Teaching Conference, Glasgow, UK, 19 Apr 2013.

2011

Muller, J.-M.V., Feige, K., Wunderlin, P., Hoedl, A., Meli, M.L., Seltenhammer, M., Grest, P., Nicolson, L., Schelling, C. and Heinzerling, L.M. (2011) Double-blind placebo-controlled study with interleukin-18 and interleukin-12 encoding plasmid DNA shows antitumor effect in metastatic melanoma in grey horses. Journal of Immunotherapy, 34(1), pp. 58-64. (doi: 10.1097/CJI.0b013e3181fe1997)

Sykes, A. , Denny, P. and Nicolson, L. (2011) PeerWise - The Marmite of Veterinary Student Learning. In: 10th European Conference on e-Learning, Brighton Business School, University of Brighton, UK., 10-11 Nov 2011, pp. 820-830. ISBN 9781908272232

2010

Hughes, K.J., Nicolson, L., Da-Costa, N., Franklin, S.H., Allen, K.J. and Dunham, S.J. (2010) Evaluation of cytokine mRNA expression in bronchoalveolar lavage cells from horses with inflammatory airway disease. Veterinary Immunology and Immunopathology, 140(1-2), pp. 83-89. (doi: 10.1016/j.vetimm.2010.11.018)

2008

Yuan, Z.Q., Nicolson, L., Marchetti, B., Gault, E.A., Campo, M.S. and Nasir, L. (2008) Transcriptional changes induced by bovine papillomavirus type 1 in equine fibroblasts. Journal of Virology, 82(13), pp. 6481-6491. (doi: 10.1128/JVI.00429-08)

2005

O'Donovan, L.H. et al. (2005) A vector expressing feline mature IL-18 fused to IL-1 beta antagonist protein signal sequence is an effective adjuvant to a DNA vaccine for feline leukaemia virus. Vaccine, 23(29), pp. 3814-3823. (doi: 10.1016/j.vaccine.2005.02.026)

2004

O'Donovan, L.H., McMonagle, E.L., Taylor, S., Argyle, D.J. and Nicolson, L. (2004) Bioactivity and secretion of interleukin-18 (IL-18) generated by equine and feline IL-18 expression constructs. Veterinary Immunology and Immunopathology, 102(4), pp. 421-428. (doi: 10.1016/j.vetimm.2004.08.003)

2003

Nart, P., Nicolson, L. and Morrison, M. (2003) No evidence for persistent enterovirus infection in cattle with end-stage idiopathic dilated cardiomyopathy. Research in Veterinary Science, 75(3), pp. 241-244. (doi: 10.1016/S0034-5288(03)00097-3)

Addie, D.D., Schaap, I.A.T., Nicolson, L. and Jarrett, O. (2003) Persistence and transmission of natural type I feline coronavirus infection. Journal of General Virology, 84(10), pp. 2735-2744.

Nart, P., Thompson, H., Williams, W., Armstrong, S.C., Barrett, D.C., Innocent, G., Morrison, M. and Nicolson, L. (2003) Investigation of bovine dilated cardiomyopathy in Holstein-Friesian cattle in the UK. Cattle Practice, 11, pp. 153-159.

2002

Schijns, V.E.J.C., Scholtes, N.C., van Zuilekom, H.I., Sanders, L.E.H.H., Nicolson, L. and Argyle, D.J. (2002) Facilitation of antibody forming responses to viral vaccine antigens in young cats by recombinant baculovirus-expressed feline IFN. Vaccine, 20(13-14), pp. 1718-1724. (doi: 10.1016/S0264-410X(02)00044-0)

Morrison, M.D., Reid, D., Onions, D., Spibey, N. and Nicolson, L. (2002) Generation of E3-deleted canine adenoviruses expressing canine parvovirus capsid by homologous recombination in bacteria. Virology, 293, pp. 26-30. (doi: 10.1006/viro.2001.1262)

2001

McMonagle, E.L.J. et al. (2001) Production of biologically active equine interleukin 12 through expression of p35, p40 and single chain IL-12 in mammalian and baculovirus expression systems. Equine Veterinary Journal, 33(7), pp. 693-698. (doi: 10.2746/042516401776249426)

Hanlon, L. et al. (2001) Feline leukemia virus DNA vaccine efficacy is enhanced by coadministration with interleukin-12 (IL-12) and IL-18 expression vectors. Journal of Virology, 75(18), pp. 8424-8433. (doi: 10.1128/JVI.75.18.8424-8433.2001)

This list was generated on Thu Nov 21 03:43:42 2024 GMT.

Jump to: Articles | Conference or Workshop Item | Conference Proceedings | Key Findings

Number of items: 17.

Articles

Addie, D.D., Schaap, I.A.T., Nicolson, L. and Jarrett, O. (2003) Persistence and transmission of natural type I feline coronavirus infection. Journal of General Virology, 84(10), pp. 2735-2744.

Conference or Workshop Item

Grosset, A. et al. (2013) Engaging Students in Peerwise: An Innovative Online Learning Approach. 6th Annual University of Glasgow Learning and Teaching Conference, Glasgow, UK, 19 Apr 2013.

Conference Proceedings

Key Findings

Nicolson, L., Rodgers, J. , Dowell, F., Nasir, L., Evans, N. , Robinson, J. and Hammond, J. Personal development plan case study. [Key Findings]