Ms Irem Denizli

  • PhD Student (Tutor), Demonstrator (Biodiversity, One Health & Veterinary Medicine Professional Services)
  • Demonstrator (MVLS Education Hub)

Biography

I hold a BSc in Molecular Biology and Genetics, followed by a year of experience working in a diagnostic laboratory. I then pursued my MSc in the Department of Molecular Biology and Genetics at Bogazici University, where my research centered on molecular toxicology and cancer regulation. During my master's studies, I gained valuable experience as a molecular biologist and a bioinformatician and provided technical support for a bioinformatics start-up, enhancing my expertise in data analysis and computational tools.

Currently, I am pursuing a PhD, where I continue to develop my research skills, with a focus on the molecular mechanisms underlying phenotype plasticity. Alongside my doctoral studies, I hold positions as a Graduate Teaching Assistant (GTA) and a lab demonstrator, where I contribute to teaching the next generation of scientists.

Research interests

My research interests lie in evolutionary biology, with a particular focus on the mechanisms driving adaptation and speciation. I am especially fascinated by the intersection of seasonal biology and evolutionary processes, investigating how organisms adapt to seasonal changes at molecular, physiological, and ecological levels. Additionally, I have a strong interest in aquatic ecosystems, where I can explore evolutionary dynamics within these environments, including the unique selective pressures and adaptive strategies exhibited by aquatic species.

Research groups

Publications

List by: Type | Date

Jump to: 2024
Number of items: 1.

2024

Marshall, C. J., Blake, A., Stewart, C., Liddle, T. A., Denizli, I., Cuthill, F., Evans, N. P. and Stevenson, T. J. (2024) Prolactin mediates long-term, seasonal rheostatic regulation of body mass in female mammals. Endocrinology, 165(4), bqae020. (doi: 10.1210/endocr/bqae020) (PMID:38417844) (PMCID:PMC10904104)

This list was generated on Sun Dec 22 04:57:29 2024 GMT.
Jump to: Articles
Number of items: 1.

Articles

Marshall, C. J., Blake, A., Stewart, C., Liddle, T. A., Denizli, I., Cuthill, F., Evans, N. P. and Stevenson, T. J. (2024) Prolactin mediates long-term, seasonal rheostatic regulation of body mass in female mammals. Endocrinology, 165(4), bqae020. (doi: 10.1210/endocr/bqae020) (PMID:38417844) (PMCID:PMC10904104)

This list was generated on Sun Dec 22 04:57:29 2024 GMT.

Supervision

My current research aims to unravel the molecular mechanisms underlying seasonal polyphenism in Siberian hamsters. This phenomenon, where organisms exhibit different phenotypes depending on the variations in photoperiod, provides a unique model for studying adaptive physiological and morphological changes. I employ a multi-omics approach that integrates next-generation sequencing technologies, such as RNA-seq, whole-genome sequencing, ChIP-Seq, with advanced bioinformatics analysis to identify key genetic and epigenetic factors driving these seasonal variations.By combining these methodologies, I aim to provide a comprehensive understanding of how environmental cues are translated into molecular signals that regulate phenotypic plasticity.