2009

O'Shaughnessy, P.J. , Morris, I.D., Huhtaniemi, I., Baker, P.J. and Abel, M.H. (2009) Role of androgen and gonadotrophins in the development and function of the Sertoli cells and Leydig cells: data from mutant and genetically modified mice. Molecular and Cellular Endocrinology, 306(1-2), pp. 2-8. (doi: 10.1016/j.mce.2008.11.005)

Fowler, P.A. et al. (2009) Gene Expression Analysis of Human Fetal Ovarian Primordial Follicle Formation. Journal of Clinical Endocrinology and Metabolism, 94(4), pp. 1427-1435. (doi: 10.1210/jc.2008-2619)

O'Shaughnessy, P.J. , Morris, I.D., Huhtaniemi, I., Baker, P.J. and Abel, M.H. (2009) Role of androgen and gonadotrophins in the development and function of the Sertoli cells and Leydig cells: Data from mutant and genetically modified mice. Molecular and Cellular Endocrinology, 306(1-2), pp. 2-8. (doi: 10.1016/j.mce.2008.11.005)

2008

Abel, M.H., Baker, P.J., Charlton, H.M., Monteiro, A., Verhoeven, G., De Gendt, K., Guillou, F. and O'Shaughnessy, P.J. (2008) Spermatogenesis and sertoli cell activity in mice lacking Sertoli cell receptors for follicle stimulating hormone and androgen. Endocrinology, 149(7), pp. 3279-3285. (doi: 10.1210/en.2008-0086)

Baker, P., Fleming, L., Mossa, F., Lonergan, P., Evans, A. and Mihm Carmichael, M. (2008) Decreased mRNA expression of dominance marker genes in preovulatory compared to newly selected dominant follicles in cattle. In: 41st Annual Meeting of the Society for the Study of Reproduction, Kona, HI, 27-30 May 2008,

Forde, N. et al. (2008) Differential expression of signal transduction factors in ovarian follicle development: a functional role for betaglycan and FIBP in granulosa cells in cattle. Physiological Genomics, 33(2), pp. 193-204. (doi: 10.1152/physiolgenomics.00274.2007)

Fowler, P.A., Cassie, S., Rhind, S.M., Brewer, M.J., Collinson, J.M., Lea, R.G., Baker, P.J., Bhattacharya, S. and O'Shaughnessy, P.J. (2008) Maternal smoking during pregnancy specifically reduces human fetal desert hedgehog gene expression during testis development. Journal of Clinical Endocrinology and Metabolism, 93(2), pp. 619-626. (doi: 10.1210/jc.2007-1860)

Mihm Carmichael, M., Baker, P.J., Fleming, L.M., Monteiro, A.M. and O'Shaughnessy, P.J. (2008) Differentiation of the bovine dominant follicle from the cohort upregulates mRNA expression for new tissue development genes. Reproduction, 135(2), pp. 253-265. (doi: 10.1530/REP-06-0193) (PMID:18239053)

2007

O'Shaughnessy, P.J. , Abel, M., Charlton, H.M., Hu, B., Johnston, H. and Baker, P.J. (2007) Altered expression of genes involved in regulation of vitamin A metabolism, solute transportation, and cytoskeletal function in the androgen-insensitive Tfm mouse testis. Endocrinology, 148, pp. 2914-2924. (doi: 10.1210/en.2006-1412)

O'Shaughnessy, P.J., Baker, P.J., Monteiro, A., Cassie, S., Bhattacharya, S. and Fowler, P.,A., (2007) Developmental changes in human fetal testicular cell numbers and messenger ribonucleic acid levels during the second trimester. Journal of Clinical Endocrinology and Metabolism, 92(12), pp. 4792-4801. (doi: 10.1210/jc.2007-1690)

2006

O'Shaughnessy, P.J. , Baker, P.J. and Johnston, H. (2006) The foetal Leydig cell - differentiation, function and regulation. International Journal of Andrology, 29, pp. 90-95. (doi: 10.1111/j.1365-2605.2005.00555.x)

2005

O'Shaughnessy, P.J. , Baker, P.J. and Johnston, H. (2005) Neuroendocrine regulation of Leydig cell development. Testicular Cell Dynamics and Endocrine Signaling, 1061, pp. 109-119. (doi: 10.1196/annals.1336.013)

2004

Johnston, H., Baker, P.J., Abel, M., Charlton, H.M., Jackson, G., Fleming, L., Kumar, T.R. and O'Shaughnessy, P.J. (2004) Regulation of Sertoli cell number and activity by follicle-stimulating hormone and androgen during postnatal development in the mouse. Endocrinology, 145, pp. 318-329. (doi: 10.1210/en.2003-1055)

2003

Baker, P.J., Johnston, H., Abel, M., Charlton, H.M. and O'Shaughnessy, P.J. (2003) Differentiation of adult-type Leydig cells occurs in gonadotrophin-deficient mice. Reproductive Biology and Endocrinology, 1(4),

Baker, P.J., Pakarinen, P., Huhtaniemi, I.T., Abel, M.H., Charlton, H.M., Kumar, T.R. and O'Shaughnessy, P.J. (2003) Failure of normal Leydig cell development in follicle-stimulating hormone (FSH) receptor-deficient mice, but not FSH beta-deficient mice: Role for constitutive FSH receptor activity. Endocrinology, 144, pp. 138-145. (doi: 10.1210/en.2002-220637)

O'Shaughnessy, P.J. , Fleming, L., Baker, P.J., Jackson, G. and Johnston, H. (2003) Identification of developmentally regulated genes in the somatic cells of the mouse testis using serial analysis of gene expression. Biology of Reproduction, 69, pp. 797-808. (doi: 10.1095/biolreprod.103.016899)

O'Shaughnessy, P.J. , Fleming, L.M., Jackson, G., Hochgeschwender, U., Reed, P. and Baker, P.J. (2003) Adrenocorticotropic hormone directly stimulates testosterone production by the fetal and neonatal mouse testis. Endocrinology, 144, pp. 3279-3284. (doi: 10.1210/en.2003-0277)

2002

O'Shaughnessy, P.J. , Johnston, H., Willerton, L. and Baker, P.J. (2002) Failure of normal adult Leydig cell development in androgen-receptor-deficient mice. Journal of Cell Science, 115, pp. 3491-3496.

O'Shaughnessy, P.J. , Willerton, L. and Baker, P.J. (2002) Changes in Leydig cell gene expression during development in the mouse. Biology of Reproduction, 66, pp. 966-975.

2001

Baker, P.J. and O'Shaughnessy, P.J. (2001) Expression of prostaglandin D synthetase during development in the mouse testis. Reproduction, 122, pp. 553-559.

Baker, P.J. and O'Shaughnessy, P.J. (2001) Role of gonadotrophins in regulating numbers of Leydig and Sertoli cells during fetal and postnatal development in mice. Reproduction, 122, pp. 227-234.

Articles

O'Shaughnessy, P.J. , Morris, I.D., Huhtaniemi, I., Baker, P.J. and Abel, M.H. (2009) Role of androgen and gonadotrophins in the development and function of the Sertoli cells and Leydig cells: data from mutant and genetically modified mice. Molecular and Cellular Endocrinology, 306(1-2), pp. 2-8. (doi: 10.1016/j.mce.2008.11.005)

Fowler, P.A. et al. (2009) Gene Expression Analysis of Human Fetal Ovarian Primordial Follicle Formation. Journal of Clinical Endocrinology and Metabolism, 94(4), pp. 1427-1435. (doi: 10.1210/jc.2008-2619)

O'Shaughnessy, P.J. , Morris, I.D., Huhtaniemi, I., Baker, P.J. and Abel, M.H. (2009) Role of androgen and gonadotrophins in the development and function of the Sertoli cells and Leydig cells: Data from mutant and genetically modified mice. Molecular and Cellular Endocrinology, 306(1-2), pp. 2-8. (doi: 10.1016/j.mce.2008.11.005)

Abel, M.H., Baker, P.J., Charlton, H.M., Monteiro, A., Verhoeven, G., De Gendt, K., Guillou, F. and O'Shaughnessy, P.J. (2008) Spermatogenesis and sertoli cell activity in mice lacking Sertoli cell receptors for follicle stimulating hormone and androgen. Endocrinology, 149(7), pp. 3279-3285. (doi: 10.1210/en.2008-0086)

Forde, N. et al. (2008) Differential expression of signal transduction factors in ovarian follicle development: a functional role for betaglycan and FIBP in granulosa cells in cattle. Physiological Genomics, 33(2), pp. 193-204. (doi: 10.1152/physiolgenomics.00274.2007)

Fowler, P.A., Cassie, S., Rhind, S.M., Brewer, M.J., Collinson, J.M., Lea, R.G., Baker, P.J., Bhattacharya, S. and O'Shaughnessy, P.J. (2008) Maternal smoking during pregnancy specifically reduces human fetal desert hedgehog gene expression during testis development. Journal of Clinical Endocrinology and Metabolism, 93(2), pp. 619-626. (doi: 10.1210/jc.2007-1860)

Mihm Carmichael, M., Baker, P.J., Fleming, L.M., Monteiro, A.M. and O'Shaughnessy, P.J. (2008) Differentiation of the bovine dominant follicle from the cohort upregulates mRNA expression for new tissue development genes. Reproduction, 135(2), pp. 253-265. (doi: 10.1530/REP-06-0193) (PMID:18239053)

O'Shaughnessy, P.J. , Abel, M., Charlton, H.M., Hu, B., Johnston, H. and Baker, P.J. (2007) Altered expression of genes involved in regulation of vitamin A metabolism, solute transportation, and cytoskeletal function in the androgen-insensitive Tfm mouse testis. Endocrinology, 148, pp. 2914-2924. (doi: 10.1210/en.2006-1412)

O'Shaughnessy, P.J., Baker, P.J., Monteiro, A., Cassie, S., Bhattacharya, S. and Fowler, P.,A., (2007) Developmental changes in human fetal testicular cell numbers and messenger ribonucleic acid levels during the second trimester. Journal of Clinical Endocrinology and Metabolism, 92(12), pp. 4792-4801. (doi: 10.1210/jc.2007-1690)

O'Shaughnessy, P.J. , Baker, P.J. and Johnston, H. (2006) The foetal Leydig cell - differentiation, function and regulation. International Journal of Andrology, 29, pp. 90-95. (doi: 10.1111/j.1365-2605.2005.00555.x)

O'Shaughnessy, P.J. , Baker, P.J. and Johnston, H. (2005) Neuroendocrine regulation of Leydig cell development. Testicular Cell Dynamics and Endocrine Signaling, 1061, pp. 109-119. (doi: 10.1196/annals.1336.013)

Johnston, H., Baker, P.J., Abel, M., Charlton, H.M., Jackson, G., Fleming, L., Kumar, T.R. and O'Shaughnessy, P.J. (2004) Regulation of Sertoli cell number and activity by follicle-stimulating hormone and androgen during postnatal development in the mouse. Endocrinology, 145, pp. 318-329. (doi: 10.1210/en.2003-1055)

Baker, P.J., Johnston, H., Abel, M., Charlton, H.M. and O'Shaughnessy, P.J. (2003) Differentiation of adult-type Leydig cells occurs in gonadotrophin-deficient mice. Reproductive Biology and Endocrinology, 1(4),

Baker, P.J., Pakarinen, P., Huhtaniemi, I.T., Abel, M.H., Charlton, H.M., Kumar, T.R. and O'Shaughnessy, P.J. (2003) Failure of normal Leydig cell development in follicle-stimulating hormone (FSH) receptor-deficient mice, but not FSH beta-deficient mice: Role for constitutive FSH receptor activity. Endocrinology, 144, pp. 138-145. (doi: 10.1210/en.2002-220637)

O'Shaughnessy, P.J. , Fleming, L., Baker, P.J., Jackson, G. and Johnston, H. (2003) Identification of developmentally regulated genes in the somatic cells of the mouse testis using serial analysis of gene expression. Biology of Reproduction, 69, pp. 797-808. (doi: 10.1095/biolreprod.103.016899)

O'Shaughnessy, P.J. , Fleming, L.M., Jackson, G., Hochgeschwender, U., Reed, P. and Baker, P.J. (2003) Adrenocorticotropic hormone directly stimulates testosterone production by the fetal and neonatal mouse testis. Endocrinology, 144, pp. 3279-3284. (doi: 10.1210/en.2003-0277)

O'Shaughnessy, P.J. , Johnston, H., Willerton, L. and Baker, P.J. (2002) Failure of normal adult Leydig cell development in androgen-receptor-deficient mice. Journal of Cell Science, 115, pp. 3491-3496.

O'Shaughnessy, P.J. , Willerton, L. and Baker, P.J. (2002) Changes in Leydig cell gene expression during development in the mouse. Biology of Reproduction, 66, pp. 966-975.

Baker, P.J. and O'Shaughnessy, P.J. (2001) Expression of prostaglandin D synthetase during development in the mouse testis. Reproduction, 122, pp. 553-559.

Baker, P.J. and O'Shaughnessy, P.J. (2001) Role of gonadotrophins in regulating numbers of Leydig and Sertoli cells during fetal and postnatal development in mice. Reproduction, 122, pp. 227-234.

Conference Proceedings

Baker, P., Fleming, L., Mossa, F., Lonergan, P., Evans, A. and Mihm Carmichael, M. (2008) Decreased mRNA expression of dominance marker genes in preovulatory compared to newly selected dominant follicles in cattle. In: 41st Annual Meeting of the Society for the Study of Reproduction, Kona, HI, 27-30 May 2008,