Illuminating the darkness: exploiting IVIS imaging technology
Published: 3 July 2014
Devaney - Illuminating the darkness: exploiting IVIS imaging technology. Gates Foundation, 2014 - 2015, £31,322.
Filariasis is a parastic disease caused by nematode worms, and can affect humans and a range of other animals. Prof Eileen Devaney and Elmarie Myburgh will determine whether parasitic filarial (thread-like) worms can be visualised in the lymphatic system of live animals. The purpose is to determine whether such visualisation can provide a means to measure, and ultimately a means of screening, for drug activity. Testing candidate anti-filarial drugs using in vivo models is preferable to the current in vitro assays, because the selected drugs are more likely to be effective in humans.
First published: 3 July 2014
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