Professor John Riddell
- Professor, Director of Research (School of Psychology & Neuroscience)
telephone:
01413304495
email:
John.Riddell@glasgow.ac.uk
Room 216 Level 2, Sir James Black Building, Glasgow G12 8QQ
https://orcid.org/0000-0001-6366-6545Research interests
Sensory and motor processing mechanism in the spinal cord, mechanisms of neuropathic pain, and plasticity and regeneration following spinal cord injury.
Spinal interneuronal circuits controlling movement.
Regeneration in the spinal cord.
Sensory processing and the mechanisms of pain.
Publications
2024
Williams, J. A. et al. (2024) Developing and investigating a nanovibration intervention for the prevention/reversal of bone loss following spinal cord injury. ACS Nano, 18(27), pp. 17630-17641. (doi: 10.1021/acsnano.4c02104) (PMID:38924391) (PMCID:PMC11238619)
Kommer, M. et al. (2024) International e-Delphi survey to define best practice in the reporting of intracranial pressure monitoring recording data. Brain and Spine, 4, 102860. (doi: 10.1016/j.bas.2024.102860) (PMID:39149423) (PMCID:PMC11325271)
2023
Boyle, K. A. et al. (2023) Neuropeptide Y-expressing dorsal horn inhibitory interneurons gate spinal pain and itch signalling. eLife, 12, RP86633. (doi: 10.7554/eLife.86633) (PMID:37490401) (PMCID:PMC10392120)
Polgár, E. et al. (2023) Grpr expression defines a population of superficial dorsal horn vertical cells that have a role in both itch and pain. Pain, 164(1), pp. 149-170. (doi: 10.1097/j.pain.0000000000002677) (PMID:35543635) (PMCID:PMC9756441)
2022
Williams, J. A., Huesa, C., Windmill, J. F. C., Purcell, M., Reid, S., Coupaud, S. and Riddell, J. S. (2022) Spatiotemporal responses of trabecular and cortical bone to complete spinal cord injury in skeletally mature rats. Bone Reports, 16, 101592. (doi: 10.1016/j.bonr.2022.101592) (PMID:35637974) (PMCID:PMC9142855)
Barki, N. et al. (2022) Chemogenetics defines the roles of short chain fatty acid receptors within the gut-brain axis. eLife, 11, e73777. (doi: 10.7554/eLife.73777) (PMID:35229717) (PMCID:PMC8887895)
2021
Nothnagel, N. D. , Symon, A., Morgan, A. T., Huber, R., Riddell, J. and Goense, J. (2021) VASO-fMRI with Nordic-PCA for laminar sensory testing at 7 Tesla. International Society for Magnetic Resonance in Medicine (ISMRM 2021), 15-20 May 2021.
2020
Hosseinzadeh, S., Lindsay, S. L. , Gallagher, A. G., Wellings, D. A., Riehle, M. O. , Riddell, J. S. and Barnett, S. C. (2020) A novel poly-ε-lysine based implant, Proliferate®, for promotion of CNS repair following spinal cord injury. Biomaterials Science, 8(13), pp. 3611-3627. (doi: 10.1039/D0BM00097C) (PMID:32515439)
2019
Brunton, E. K., Silveira, C., Rosenberg, J., Schiefer, M. A., Riddell, J. and Nazarpour, K. (2019) Temporal modulation of the response of sensory fibers to paired-pulse stimulation. IEEE Transactions on Neural Systems and Rehabilitation Engineering, 27(9), pp. 1676-1683. (doi: 10.1109/TNSRE.2019.2935813) (PMID:31425119)
Dickie, A. C. et al. (2019) Morphological and functional properties distinguish the substance P and gastrin-releasing peptide subsets of excitatory interneuron in the spinal cord dorsal horn. Pain, 160(2), pp. 442-462. (doi: 10.1097/j.pain.0000000000001406) (PMID:30247267) (PMCID:PMC6330098)
2018
Huang, J. et al. (2018) Author correction: circuit dissection of the role of somatostatin in itch and pain. Nature Neuroscience, 21(6), p. 894. (doi: 10.1038/s41593-018-0149-6) (PMID:29674654)
Huang, J. et al. (2018) Circuit dissection of the role of somatostatin in itch and pain. Nature Neuroscience, 21(5), pp. 707-716. (doi: 10.1038/s41593-018-0119-z) (PMID:29556030) (PMCID:PMC5923877)
2017
Hulme, C.H., Brown, S.J., Fuller, H.R., Riddell, J. , Osman, A., Chowdhury, J., Kumar, N., Johnson, W.E. and Wright, K.T. (2017) The developing landscape of diagnostic and prognostic biomarkers for spinal cord injury in cerebrospinal fluid and blood. Spinal Cord, 55(2), pp. 114-125. (doi: 10.1038/sc.2016.174) (PMID:27995945)
Lindsay, S. L. , Toft, A., Griffin, J., Emraja, A. M.M., Barnett, S. C. and Riddell, J. (2017) Human olfactory mesenchymal stromal cell transplants promote remyelination and earlier improvement in gait co-ordination after spinal cord injury. Glia, 65(4), pp. 639-656. (doi: 10.1002/glia.23117) (PMID:28144983) (PMCID:PMC5324664)
O'Neill, P., Lindsay, S. L. , Pantiru, A., Guimond, S. E., Fagoe, N., Verhaagen, J., Turnbull, J. E., Riddell, J. S. and Barnett, S. C. (2017) Sulfatase mediated manipulation of the astrocyte-Schwann cell interface. Glia, 65(1), pp. 19-33. (doi: 10.1002/glia.23047) (PMID:27535874) (PMCID:PMC5244676)
2016
Iwagaki, N., Ganley, R. P., Dickie, A., Polgár, E., Hughes, D. I. , Del Rio, P., Revina, Y., Watanabe, M., Todd, A. J. and Riddell, J. S. (2016) A combined electrophysiological and morphological study of NPY-expressing inhibitory interneurons in the spinal dorsal horn of the mouse. Pain, 157(3), pp. 598-612. (doi: 10.1097/j.pain.0000000000000407) (PMID:26882346) (PMCID:PMC4751741)
2015
Ganley, R. P. et al. (2015) Inhibitory interneurons that express GFP in the PrP-GFP mouse spinal cord are morphologically heterogeneous, innervated by several classes of primary afferent and include lamina I projection neurons among their postsynaptic targets. Journal of Neuroscience, 35(19), pp. 7626-7642. (doi: 10.1523/JNEUROSCI.0406-15.2015) (PMID:25972186) (PMCID:PMC4429159)
2014
Gadalla, K. K.E. , Ross, P. D., Riddell, J. S. , Bailey, M. E.S. and Cobb, S. R. (2014) Gait analysis in a Mecp2 knockout mouse model of Rett syndrome reveals early-onset and progressive motor deficits. PLoS ONE, 9(11), e112889. (doi: 10.1371/journal.pone.0112889) (PMID:25392929) (PMCID:PMC4231076)
Yasaka, T., Tiong, S. Y.X., Polgár, E., Watanabe, M., Kumamoto, E., Riddell, J. S. and Todd, A. J. (2014) A putative relay circuit providing low-threshold mechanoreceptive input to lamina I projection neurons via vertical cells in lamina II of the rat dorsal horn. Molecular Pain, 10(1), p. 3. (doi: 10.1186/1744-8069-10-3)
2013
Lindsay, S. , Toft, A., Riddell, J. and Barnett, S. C. (2013) Human Olfactory-derived Mesenchymal Stem Cell Transplantation as a Candidate for CNS Repair. Glia 63(S1):E428. Meeting Abstract: XII European Meeting on Glial Cell Function in Health and Disease, Bilbao, Spain, 15-18th July 2015. (doi: 10.1002/glia.22870)
Toft, A., Tome, M., Barnett, S.C. and Riddell, J.S. (2013) A comparative study of glial and non-neural cell properties for transplant-mediated repair of the injured spinal cord. Glia, 61(4), pp. 513-528. (doi: 10.1002/glia.22452)
Ewing, S.G., Porr, B. , Riddell, J.S. , Winter, C. and Grace, A.A. (2013) SaBer DBS: a fully programmable, rechargeable, bilateral, charge-balanced preclinical microstimulator for long-term neural stimulation. Journal of Neuroscience Methods, 213(2), pp. 228-235. (doi: 10.1016/j.jneumeth.2012.12.008)
Iwagaki, N., Garzillo, F., Polgár, E., Riddell, J.S. and Todd, A.J. (2013) Neurochemical characterisation of lamina II inhibitory interneurons that express GFP in the PrP-GFP mouse. Molecular Pain, 9(56), (doi: 10.1186/1744-8069-9-56)
2012
Toft, A., Tomé, M., Lindsay, S.L. , Barnett, S.C. and Riddell, J.S. (2012) Transplant-mediated repair properties of rat olfactory mucosal OM-I and OM-II sphere-forming cells. Journal of Neuroscience Research, 90(3), pp. 619-631. (doi: 10.1002/jnr.22789)
2010
Yasaka, T., Tiong, S.Y.X., Hughes, D.I. , Riddell, J.S. and Todd, A.J. (2010) Populations of inhibitory and excitatory interneurons in lamina II of the adult rat spinal dorsal horn revealed by a combined electrophysiological and anatomical approach. Pain, 151(2), pp. 475-488. (doi: 10.1016/j.pain.2010.08.008)
Lindsay, S. L. , Riddell, J. S. and Barnett, S. C. (2010) Olfactory mucosa for transplant-mediated repair: a complex tissue for a complex injury? Glia, 58(2), pp. 125-134. (doi: 10.1002/glia.20917)
2009
Yasaka, T., Hughes, D.I. , Polgár, E., Nagy, G.G., Watanabe, M., Riddell, J.S. and Todd, A.J. (2009) Evidence against AMPA receptor-lacking glutamatergic synapses in the superficial dorsal horn of the rat spinal cord. Journal of Neuroscience, 29(42), pp. 13401-13409. (doi: 10.1523/JNEUROSCI.2628-09.2009)
Tome, M., Lindsay, S. L., Riddell, J. S. and Barnett, S. C. (2009) Identification of nonepithelial multipotent cells in the embryonic olfactory mucosa. Stem Cells, 27(9), pp. 2196-2208. (doi: 10.1002/stem.130) (PMID:19544421)
2007
Santos-Silva, A., Fairless, R., Frame, M.C., Montague, P., Smith, G.M., Toft, A., Riddell, J.S. and Barnett, S.C. (2007) FGF/heparin differentially regulates Schwann cell and olfactory ensheathing cell interactions with astrocytes: a role in astrocytosis. Journal of Neuroscience, 27(27), pp. 7154-7167. (doi: 10.1523/JNEUROSCI.1184-07.2007)
Hughes, D.I. , Scott, D.T., Riddell, J.S. and Todd, A.J. (2007) Up-regulation of substance P in low-threshold myelinated afferents is not required for tactile allodynia in the chronic constriction injury and spinal nerve ligation models. Journal of Neuroscience, 27(8), pp. 2035-2044. (doi: 10.1523/JNEUROSCI.5401-06.2007)
Barnett, S. and Riddell, J. (2007) Olfactory ensheathing cell transplantation as a strategy for spinal cord repair - what can it achieve? Nature Clinical Practice Neurology, 3(3), pp. 152-161. (doi: 10.1038/ncpneuro0447)
Hughes, D.I. , Scott, D.T., Riddell, J.S. and Todd, A.J. (2007) Upregulation of substance P in low-threshold myelinated afferents is not required for tactile allodynia in the chronic constriction injury and spinal nerve ligation models. Journal of Neuroscience, 27(8), pp. 2035-2044. (doi: 10.1523/JNEUROSCI.5401-06.2007)
Toft, A., Scott, D., Barnett, S. and Riddell, J. (2007) Electrophysiological evidence that olfactory cell transplants improve function after spinal cord injury. Brain, 130(4), pp. 970-984. (doi: 10.1093/brain/awm040)
2005
Hughes, D.I. et al. (2005) P boutons in lamina IX of the rodent spinal cord express high levels of glutamic acid decarboxylase-65 and originate from cells in deep medial dorsal horn. Proceedings of the National Academy of Sciences of the United States of America, 102(25), pp. 9038-9043. (doi: 10.1073/pnas.0503646102)
2004
Barnett, S. and Riddell, J. (2004) Olfactory ensheathing cells (OECs) and the treatment of CNS injury: advantages and possible caveats. Journal of Anatomy, 204(1), pp. 57-67. (doi: 10.1111/j.1469-7580.2004.00257.x)
Polgár, E., Gray, S., Riddell, J. and Todd, A. (2004) Lack of evidence for significant neuronal loss in laminae I-III of the spinal dorsal horn of the rat in the chronic constriction injury model. Pain, 111, pp. 144-150. (doi: 10.1016/j.pain.2004.06.011)
Riddell, J., Enriquez-Denton, M., Toft, A., Fairless, R. and Barnett, S. (2004) Olfactory ensheathing cell grafts have minimal influence on regeneration at the dorsal root entry zone following rhizotomy. Glia, 47, pp. 150-167. (doi: 10.1002/glia.20041)
2003
Hughes, D.I. , Scott, D.T., Todd, A.J. and Riddell, J.S. (2003) Lack of evidence for sprouting of Aβ afferents into the superficial laminas of the spinal cord dorsal horn after nerve section. Journal of Neuroscience, 23(29), pp. 9491-9499.
Polgár, E., Hughes, D.I. , Riddell, J.S. , Maxwell, D.J. , Puskár, Z. and Todd, A.J. (2003) Selective loss of spinal GABAergic or glycinergic neurons is not necessary for development of thermal hyperalgesia in the chronic constriction injury model of neuropathic pain. Pain, 104(1), pp. 229-239. (doi: 10.1016/S0304-3959(03)00011-3)
Hughes, D., Scott, D., Todd, A. and Riddell, J. (2003) Lack of evidence for sprouting of A beta afferents into the superficial laminas of the spinal cord dorsal horn after nerve section. Journal of Neuroscience, 23, pp. 9491-9499.
2002
Sutherland, F., Bannatyne, B., Kerr, R., Riddell, J. and Maxwell, D. (2002) Inhibitory amino acid transmitters associated with axons in presynaptic apposition to cutaneous primary afferent axons in the cat spinal cord. Journal of Comparative Neurology, 452, pp. 154-162. (doi: 10.1002/cne.10374)
Articles
Williams, J. A. et al. (2024) Developing and investigating a nanovibration intervention for the prevention/reversal of bone loss following spinal cord injury. ACS Nano, 18(27), pp. 17630-17641. (doi: 10.1021/acsnano.4c02104) (PMID:38924391) (PMCID:PMC11238619)
Kommer, M. et al. (2024) International e-Delphi survey to define best practice in the reporting of intracranial pressure monitoring recording data. Brain and Spine, 4, 102860. (doi: 10.1016/j.bas.2024.102860) (PMID:39149423) (PMCID:PMC11325271)
Boyle, K. A. et al. (2023) Neuropeptide Y-expressing dorsal horn inhibitory interneurons gate spinal pain and itch signalling. eLife, 12, RP86633. (doi: 10.7554/eLife.86633) (PMID:37490401) (PMCID:PMC10392120)
Polgár, E. et al. (2023) Grpr expression defines a population of superficial dorsal horn vertical cells that have a role in both itch and pain. Pain, 164(1), pp. 149-170. (doi: 10.1097/j.pain.0000000000002677) (PMID:35543635) (PMCID:PMC9756441)
Williams, J. A., Huesa, C., Windmill, J. F. C., Purcell, M., Reid, S., Coupaud, S. and Riddell, J. S. (2022) Spatiotemporal responses of trabecular and cortical bone to complete spinal cord injury in skeletally mature rats. Bone Reports, 16, 101592. (doi: 10.1016/j.bonr.2022.101592) (PMID:35637974) (PMCID:PMC9142855)
Barki, N. et al. (2022) Chemogenetics defines the roles of short chain fatty acid receptors within the gut-brain axis. eLife, 11, e73777. (doi: 10.7554/eLife.73777) (PMID:35229717) (PMCID:PMC8887895)
Hosseinzadeh, S., Lindsay, S. L. , Gallagher, A. G., Wellings, D. A., Riehle, M. O. , Riddell, J. S. and Barnett, S. C. (2020) A novel poly-ε-lysine based implant, Proliferate®, for promotion of CNS repair following spinal cord injury. Biomaterials Science, 8(13), pp. 3611-3627. (doi: 10.1039/D0BM00097C) (PMID:32515439)
Brunton, E. K., Silveira, C., Rosenberg, J., Schiefer, M. A., Riddell, J. and Nazarpour, K. (2019) Temporal modulation of the response of sensory fibers to paired-pulse stimulation. IEEE Transactions on Neural Systems and Rehabilitation Engineering, 27(9), pp. 1676-1683. (doi: 10.1109/TNSRE.2019.2935813) (PMID:31425119)
Dickie, A. C. et al. (2019) Morphological and functional properties distinguish the substance P and gastrin-releasing peptide subsets of excitatory interneuron in the spinal cord dorsal horn. Pain, 160(2), pp. 442-462. (doi: 10.1097/j.pain.0000000000001406) (PMID:30247267) (PMCID:PMC6330098)
Huang, J. et al. (2018) Author correction: circuit dissection of the role of somatostatin in itch and pain. Nature Neuroscience, 21(6), p. 894. (doi: 10.1038/s41593-018-0149-6) (PMID:29674654)
Huang, J. et al. (2018) Circuit dissection of the role of somatostatin in itch and pain. Nature Neuroscience, 21(5), pp. 707-716. (doi: 10.1038/s41593-018-0119-z) (PMID:29556030) (PMCID:PMC5923877)
Hulme, C.H., Brown, S.J., Fuller, H.R., Riddell, J. , Osman, A., Chowdhury, J., Kumar, N., Johnson, W.E. and Wright, K.T. (2017) The developing landscape of diagnostic and prognostic biomarkers for spinal cord injury in cerebrospinal fluid and blood. Spinal Cord, 55(2), pp. 114-125. (doi: 10.1038/sc.2016.174) (PMID:27995945)
Lindsay, S. L. , Toft, A., Griffin, J., Emraja, A. M.M., Barnett, S. C. and Riddell, J. (2017) Human olfactory mesenchymal stromal cell transplants promote remyelination and earlier improvement in gait co-ordination after spinal cord injury. Glia, 65(4), pp. 639-656. (doi: 10.1002/glia.23117) (PMID:28144983) (PMCID:PMC5324664)
O'Neill, P., Lindsay, S. L. , Pantiru, A., Guimond, S. E., Fagoe, N., Verhaagen, J., Turnbull, J. E., Riddell, J. S. and Barnett, S. C. (2017) Sulfatase mediated manipulation of the astrocyte-Schwann cell interface. Glia, 65(1), pp. 19-33. (doi: 10.1002/glia.23047) (PMID:27535874) (PMCID:PMC5244676)
Iwagaki, N., Ganley, R. P., Dickie, A., Polgár, E., Hughes, D. I. , Del Rio, P., Revina, Y., Watanabe, M., Todd, A. J. and Riddell, J. S. (2016) A combined electrophysiological and morphological study of NPY-expressing inhibitory interneurons in the spinal dorsal horn of the mouse. Pain, 157(3), pp. 598-612. (doi: 10.1097/j.pain.0000000000000407) (PMID:26882346) (PMCID:PMC4751741)
Ganley, R. P. et al. (2015) Inhibitory interneurons that express GFP in the PrP-GFP mouse spinal cord are morphologically heterogeneous, innervated by several classes of primary afferent and include lamina I projection neurons among their postsynaptic targets. Journal of Neuroscience, 35(19), pp. 7626-7642. (doi: 10.1523/JNEUROSCI.0406-15.2015) (PMID:25972186) (PMCID:PMC4429159)
Gadalla, K. K.E. , Ross, P. D., Riddell, J. S. , Bailey, M. E.S. and Cobb, S. R. (2014) Gait analysis in a Mecp2 knockout mouse model of Rett syndrome reveals early-onset and progressive motor deficits. PLoS ONE, 9(11), e112889. (doi: 10.1371/journal.pone.0112889) (PMID:25392929) (PMCID:PMC4231076)
Yasaka, T., Tiong, S. Y.X., Polgár, E., Watanabe, M., Kumamoto, E., Riddell, J. S. and Todd, A. J. (2014) A putative relay circuit providing low-threshold mechanoreceptive input to lamina I projection neurons via vertical cells in lamina II of the rat dorsal horn. Molecular Pain, 10(1), p. 3. (doi: 10.1186/1744-8069-10-3)
Toft, A., Tome, M., Barnett, S.C. and Riddell, J.S. (2013) A comparative study of glial and non-neural cell properties for transplant-mediated repair of the injured spinal cord. Glia, 61(4), pp. 513-528. (doi: 10.1002/glia.22452)
Ewing, S.G., Porr, B. , Riddell, J.S. , Winter, C. and Grace, A.A. (2013) SaBer DBS: a fully programmable, rechargeable, bilateral, charge-balanced preclinical microstimulator for long-term neural stimulation. Journal of Neuroscience Methods, 213(2), pp. 228-235. (doi: 10.1016/j.jneumeth.2012.12.008)
Iwagaki, N., Garzillo, F., Polgár, E., Riddell, J.S. and Todd, A.J. (2013) Neurochemical characterisation of lamina II inhibitory interneurons that express GFP in the PrP-GFP mouse. Molecular Pain, 9(56), (doi: 10.1186/1744-8069-9-56)
Toft, A., Tomé, M., Lindsay, S.L. , Barnett, S.C. and Riddell, J.S. (2012) Transplant-mediated repair properties of rat olfactory mucosal OM-I and OM-II sphere-forming cells. Journal of Neuroscience Research, 90(3), pp. 619-631. (doi: 10.1002/jnr.22789)
Yasaka, T., Tiong, S.Y.X., Hughes, D.I. , Riddell, J.S. and Todd, A.J. (2010) Populations of inhibitory and excitatory interneurons in lamina II of the adult rat spinal dorsal horn revealed by a combined electrophysiological and anatomical approach. Pain, 151(2), pp. 475-488. (doi: 10.1016/j.pain.2010.08.008)
Lindsay, S. L. , Riddell, J. S. and Barnett, S. C. (2010) Olfactory mucosa for transplant-mediated repair: a complex tissue for a complex injury? Glia, 58(2), pp. 125-134. (doi: 10.1002/glia.20917)
Yasaka, T., Hughes, D.I. , Polgár, E., Nagy, G.G., Watanabe, M., Riddell, J.S. and Todd, A.J. (2009) Evidence against AMPA receptor-lacking glutamatergic synapses in the superficial dorsal horn of the rat spinal cord. Journal of Neuroscience, 29(42), pp. 13401-13409. (doi: 10.1523/JNEUROSCI.2628-09.2009)
Tome, M., Lindsay, S. L., Riddell, J. S. and Barnett, S. C. (2009) Identification of nonepithelial multipotent cells in the embryonic olfactory mucosa. Stem Cells, 27(9), pp. 2196-2208. (doi: 10.1002/stem.130) (PMID:19544421)
Santos-Silva, A., Fairless, R., Frame, M.C., Montague, P., Smith, G.M., Toft, A., Riddell, J.S. and Barnett, S.C. (2007) FGF/heparin differentially regulates Schwann cell and olfactory ensheathing cell interactions with astrocytes: a role in astrocytosis. Journal of Neuroscience, 27(27), pp. 7154-7167. (doi: 10.1523/JNEUROSCI.1184-07.2007)
Hughes, D.I. , Scott, D.T., Riddell, J.S. and Todd, A.J. (2007) Up-regulation of substance P in low-threshold myelinated afferents is not required for tactile allodynia in the chronic constriction injury and spinal nerve ligation models. Journal of Neuroscience, 27(8), pp. 2035-2044. (doi: 10.1523/JNEUROSCI.5401-06.2007)
Barnett, S. and Riddell, J. (2007) Olfactory ensheathing cell transplantation as a strategy for spinal cord repair - what can it achieve? Nature Clinical Practice Neurology, 3(3), pp. 152-161. (doi: 10.1038/ncpneuro0447)
Hughes, D.I. , Scott, D.T., Riddell, J.S. and Todd, A.J. (2007) Upregulation of substance P in low-threshold myelinated afferents is not required for tactile allodynia in the chronic constriction injury and spinal nerve ligation models. Journal of Neuroscience, 27(8), pp. 2035-2044. (doi: 10.1523/JNEUROSCI.5401-06.2007)
Toft, A., Scott, D., Barnett, S. and Riddell, J. (2007) Electrophysiological evidence that olfactory cell transplants improve function after spinal cord injury. Brain, 130(4), pp. 970-984. (doi: 10.1093/brain/awm040)
Hughes, D.I. et al. (2005) P boutons in lamina IX of the rodent spinal cord express high levels of glutamic acid decarboxylase-65 and originate from cells in deep medial dorsal horn. Proceedings of the National Academy of Sciences of the United States of America, 102(25), pp. 9038-9043. (doi: 10.1073/pnas.0503646102)
Barnett, S. and Riddell, J. (2004) Olfactory ensheathing cells (OECs) and the treatment of CNS injury: advantages and possible caveats. Journal of Anatomy, 204(1), pp. 57-67. (doi: 10.1111/j.1469-7580.2004.00257.x)
Polgár, E., Gray, S., Riddell, J. and Todd, A. (2004) Lack of evidence for significant neuronal loss in laminae I-III of the spinal dorsal horn of the rat in the chronic constriction injury model. Pain, 111, pp. 144-150. (doi: 10.1016/j.pain.2004.06.011)
Riddell, J., Enriquez-Denton, M., Toft, A., Fairless, R. and Barnett, S. (2004) Olfactory ensheathing cell grafts have minimal influence on regeneration at the dorsal root entry zone following rhizotomy. Glia, 47, pp. 150-167. (doi: 10.1002/glia.20041)
Hughes, D.I. , Scott, D.T., Todd, A.J. and Riddell, J.S. (2003) Lack of evidence for sprouting of Aβ afferents into the superficial laminas of the spinal cord dorsal horn after nerve section. Journal of Neuroscience, 23(29), pp. 9491-9499.
Polgár, E., Hughes, D.I. , Riddell, J.S. , Maxwell, D.J. , Puskár, Z. and Todd, A.J. (2003) Selective loss of spinal GABAergic or glycinergic neurons is not necessary for development of thermal hyperalgesia in the chronic constriction injury model of neuropathic pain. Pain, 104(1), pp. 229-239. (doi: 10.1016/S0304-3959(03)00011-3)
Hughes, D., Scott, D., Todd, A. and Riddell, J. (2003) Lack of evidence for sprouting of A beta afferents into the superficial laminas of the spinal cord dorsal horn after nerve section. Journal of Neuroscience, 23, pp. 9491-9499.
Sutherland, F., Bannatyne, B., Kerr, R., Riddell, J. and Maxwell, D. (2002) Inhibitory amino acid transmitters associated with axons in presynaptic apposition to cutaneous primary afferent axons in the cat spinal cord. Journal of Comparative Neurology, 452, pp. 154-162. (doi: 10.1002/cne.10374)
Conference or Workshop Item
Nothnagel, N. D. , Symon, A., Morgan, A. T., Huber, R., Riddell, J. and Goense, J. (2021) VASO-fMRI with Nordic-PCA for laminar sensory testing at 7 Tesla. International Society for Magnetic Resonance in Medicine (ISMRM 2021), 15-20 May 2021.
Lindsay, S. , Toft, A., Riddell, J. and Barnett, S. C. (2013) Human Olfactory-derived Mesenchymal Stem Cell Transplantation as a Candidate for CNS Repair. Glia 63(S1):E428. Meeting Abstract: XII European Meeting on Glial Cell Function in Health and Disease, Bilbao, Spain, 15-18th July 2015. (doi: 10.1002/glia.22870)
Grants
Grants and Awards listed are those received whilst working with the University of Glasgow.
- Using functional MRI to investigate cortical plasticity following facial reanimation surgery
Dr Stephen Plumpton Charitable Trust
2025 - 2025
- Defining the potential for neuromodulation of nociresponsive somatosensory cortex to treat pain
Pain Relief Foundation
2024 - 2027
- The roles of functionally defined populations of lamina I projection neurons
Medical Research Council
2022 - 2024
- What information does laminar fMRI provide about cortical sensorimotor circuits? Validation with electrophysiology and targeted nerve injuries
Biotechnology and Biological Sciences Research Council
2019 - 2022
- Early diagnosis and intervention of osteoporosis using nanovibrational stimulation
Science and Technology Facilities Council
2018 - 2020
- Neuronal circuits for itch in the spinal dorsal horn
Medical Research Council
2018 - 2021
- Laminar fMRI and restigg-state fMRI in the somatosensory system -- effect of peripheral nerve injury on cortical circuits
Medical Research Council
2018 - 2020
- Laminar fMRI and resting-state fMRI in the somatosensory system -- effect of peripheral nerve injury on cortical circuits
Medical Research Council
2018 - 2020
- Mechanisms of neuropathic pain following spinal cord injury: role of the spinothalamic tract
Inspire Foundation
2017 - 2021
- Mechanisms of neuropathic pain following spinal cord injury: role of the spinothalamic tract
The Inspire Foundation
2017 - 2023
- Determining the role of calretinin-RorB spinal interneurons in modulating mechanical pain
Biotechnology and Biological Sciences Research Council
2017 - 2020
- Development of laminar resting state fMRI and investigation of plasticity of cortical networks after peripheral nerve injury
Neurosciences Foundation
2017 - 2018
- The role of NPY-containing inhibitory interneurons in spinal pain pathways
Biotechnology and Biological Sciences Research Council
2016 - 2019
- Spinal inhibitory interneurons that suppress itch
Medical Research Council
2013 - 2016
- Novel strategies for promoting CNS repair through manipulation of FGF signalling and heparan sulphate proteoglycans
Medical Research Council
2013 - 2015
- Does cellular niche affect the repair potential of mesenchymal stem cells; implications for spinal cord injury?
Medical Research Council
2012 - 2015
- Populations of inhibitory interneurons in the superficial dorsal horn of the spinal cord.
Biotechnology and Biological Sciences Research Council
2012 - 2015
- How does function in long axonal tracts and local circuits change in the progression from acute to chronic stages of spinal cord injury and how effective are cell transplants?
Spinal Research
2011 - 2014
- Can olfactory mesenchymal stem cells influence the repair potential of olfactory ensheathing cells?
Wings for Life
2010 - 2013
- Confocal microscopic studies in Neuroscience
Wellcome Trust
2010 - 2013
- Do experimental treatments for spinal cord injury induce functional plasticity in spared pathways?
International Spinal Research Trust
2008 - 2011
- Characterisation of olfactory glial and stem cells from human olfactory mucosa
Scottish Executive Health Department
2008 - 2010
- Do transplants of olfactory ensheathing cells promote increased sparing in a spinal cord contusion injury model?
Tenovus Scotland
2007 - 2008
- The role of spinal GluR4 containing AMPA receptors in pain mechanisms
Tenovus Scotland
2007 - 2007
- Molecular mechanisms controlling the regenerative response of dorsal root axons following avulsion injury
Neurosciences Foundation
2006 - 2008
- AMPA receptors in the spinal dorsal horn - synaptic distribution and plasticity in pain states
Wellcome Trust
2006 - 2010
- The use of olfactory epithelial stem cells for CNS repair
Medical Research Council
2004 - 2007
- Spinal mechanisms underlying chronic pain - quantitative physiological characteristics of lamina 1 spinoparabrachial neurones in different..
Wellcome Trust
2004 - 2005
- The actions of group II interneurones in spinal cord circuitry controlling locomotion
Wellcome Trust
2003 - 2007
- Confocal microscopic studies in the spinal cord
Wellcome Trust
2002 - 2005
- An Investigation of Spinal Cord Mechanisms Underlying Neuropathic Pain in Nerve Injury Models in the Rat
Wellcome Trust
2000 - 2006
Supervision
Supervised Postgraduate Students
- Kayleigh Kanakis (Postgraduate)
- Maya Kommer (Postgraduate)
Research Assistants
- Paula Aragoneses (Research Assistant)
- Andrew Bell (Research Fellow)
- Nils Nothnagel (Research Associate)
Technicians
- Declan Bolster (Imaging Physics Manager)
- Allan McVie (Chief Technician)
Visiting Collaborator
- Jane Brandon (Visiting Researcher)
Research datasets
2023
Todd, A. , Quillet, R., Gutierrez-Mecinas, M. , Boyle, K., Polgar, E., Dickie, A. and Riddell, J. (2023) Synaptic circuits involving gastrin-releasing peptide receptor-expressing neurons in the dorsal horn of the mouse spinal cord. [Data Collection]
Todd, A. , Boyle, K., Polgar, E., Gutierrez-Mecinas, M. , Dickie, A., Cooper, A., Bell, A., Jumolea, M. E., Casas-Benito, A., Watanabe, M., Hughes, D., Weir, G. and Riddell, J. (2023) Neuropeptide Y-expressing dorsal horn inhibitory interneurons gate spinal pain and itch signalling. [Data Collection]
Additional information
Grant Advisory Board
- 2001: EU - Expert Evaluator EEC grants
Invited International Presentations
- 2005: Copenhagen, Denmark - Acta Physiologica Scandanavia International Symposium 'Plasticity and regeneration of the spinal cord and peripheral nervous system'
- 2003: Fukuoka, Japan - Seminar, Kyushu University
- 2002: Canada - Seminar, Spinal Cord Research Centre, University of Manitoba
- 2002: Paris, France - Invited speaker Federation of European Neurosceince Societies, Satellite symposium
Professional Learned Society
- 1997 - present: British Neuroscience Association - Member
- 1997 - present: Society for Neuroscience - Member
- 1996 - present: European Neuroscience Association - Member
- 1990 - present: Physiological Society - Convenor of Sensorimotor Control Group1994-1999, Organiser of Symposium, Glasgow 1999
Research Fellowship
- 1995 - 1998: McNaught Bequest Fellowship
- 1990 - 1995: Wellcome Trust Research Fellowship
