Mr Steven McFarlane

  • Research Project Support (Virology)

telephone: 01413303922
email: Steven.McFarlane@glasgow.ac.uk

MRC-UofG CVR, Sir Michael Stoker Building, Garscube Estate, 464 Bearsden Road. Glasgow, G61 1qh

Import to contacts

Research interests

CVR logo 

Member of the Boutell group.

Publications

List by: Type | Date

Jump to: 2024 | 2023 | 2021 | 2020 | 2019 | 2018 | 2016 | 2011
Number of items: 11.

2024

Francois, A. K. et al. (2024) Single-genome analysis reveals heterogeneous association of the herpes simplex virus genome with H3K27me2 and the reader PHF20L1 following infection of human fibroblasts. mBio, (doi: 10.1128/mbio.03278-23) (PMID:32753500) (PMCID:PMC7407090) (Early Online Publication)

2023

Montezano, A. C. et al. (2023) SARS-CoV-2 spike protein induces endothelial inflammation via ACE2 independently of viral replication. Scientific Reports, 13, 14086. (doi: 10.1038/s41598-023-41115-3) (PMID:37640791) (PMCID:PMC10462711)

2021

Herder, V. et al. (2021) Elevated temperature inhibits SARS-CoV-2 replication in respiratory epithelium independently of IFN-mediated innate immune defences. PLoS Biology, 19(12), e3001065. (doi: 10.1371/journal.pbio.3001065) (PMID:34932557) (PMCID:PMC8765667)

Charman, M. et al. (2021) Constitutive TRIM22 expression in the respiratory tract confers a pre-existing defence against influenza A virus infection. Frontiers in Cellular and Infection Microbiology, 11, 689707. (doi: 10.3389/fcimb.2021.689707) (PMID:34621686) (PMCID:PMC8490869)

Rihn, S. J. et al. (2021) A plasmid DNA-launched SARS-CoV-2 reverse genetics system and coronavirus toolkit for COVID-19 research. PLoS Biology, 19(2), e3001091. (doi: 10.1371/journal.pbio.3001091) (PMID:33630831) (PMCID:PMC7906417)

2020

Stokes, S., Almire, F., Tatham, M. H., McFarlane, S., Mertens, P., Pondeville, E. and Boutell, C. (2020) The SUMOylation pathway suppresses arbovirus replication in Aedes aegypti cells. PLoS Pathogens, 16(12), e1009134. (doi: 10.1371/journal.ppat.1009134) (PMID:33351855) (PMCID:PMC7802965)

2019

McFarlane, S. et al. (2019) The histone chaperone HIRA promotes the induction of host innate immune defences in response to HSV-1 infection. PLoS Pathogens, 15(3), e1007667. (doi: 10.1371/journal.ppat.1007667) (PMID:30901352) (PMCID:PMC6472835)

2018

Alandijany, T., Roberts, A. P.E., Conn, K. L., Loney, C. , McFarlane, S., Orr, A. and Boutell, C. (2018) Distinct temporal roles for the promyelocytic leukaemia (PML) protein in the sequential regulation of intracellular host immunity to HSV-1 infection. PLoS Pathogens, 14(1), e1006769. (doi: 10.1371/journal.ppat.1006769) (PMID:29309427) (PMCID:PMC5757968)

2016

Brown, J. R., Conn, K. L., Wasson, P., Charman, M., Tong, L., Grant, K., McFarlane, S. and Boutell, C. (2016) The SUMO Ligase Protein Inhibitor of Activated STAT 1 (PIAS1) is a constituent PML-NB protein that contributes to the intrinsic antiviral immune response to herpes simplex virus 1 (HSV-1). Journal of Virology, 90, 13. (doi: 10.1128/JVI.00426-16) (PMID:27099310) (PMCID:PMC4907222)

Conn, K. L., Wasson, P., McFarlane, S., Tong, L., Brown, J. R., Grant, K. G., Domingues, P. and Boutell, C. (2016) A novel role for Protein Inhibitor of Activated STAT 4 (PIAS4) in the restriction of herpes simplex virus 1 (HSV-1) by the cellular intrinsic antiviral immune response. Journal of Virology, 90(9), pp. 4807-4826. (doi: 10.1128/JVI.03055-15) (PMID:26937035)

2011

Boutell, C. , Cuchet, D., Vanni, E., Orr, A., Glass, M., McFarlane, S. and Everett, R.D. (2011) A viral ubiquitin ligase has substrate preferential SUMO targeted ubiquitin ligase activity that counteracts intrinsic antiviral defence. PLoS Pathogens, 7(9), e1002245. (doi: 10.1371/journal.ppat.1002245) (PMID:21949651) (PMCID:PMC3174244)

This list was generated on Thu Nov 21 04:58:59 2024 GMT.
Jump to: Articles
Number of items: 11.

Articles

Francois, A. K. et al. (2024) Single-genome analysis reveals heterogeneous association of the herpes simplex virus genome with H3K27me2 and the reader PHF20L1 following infection of human fibroblasts. mBio, (doi: 10.1128/mbio.03278-23) (PMID:32753500) (PMCID:PMC7407090) (Early Online Publication)

Montezano, A. C. et al. (2023) SARS-CoV-2 spike protein induces endothelial inflammation via ACE2 independently of viral replication. Scientific Reports, 13, 14086. (doi: 10.1038/s41598-023-41115-3) (PMID:37640791) (PMCID:PMC10462711)

Herder, V. et al. (2021) Elevated temperature inhibits SARS-CoV-2 replication in respiratory epithelium independently of IFN-mediated innate immune defences. PLoS Biology, 19(12), e3001065. (doi: 10.1371/journal.pbio.3001065) (PMID:34932557) (PMCID:PMC8765667)

Charman, M. et al. (2021) Constitutive TRIM22 expression in the respiratory tract confers a pre-existing defence against influenza A virus infection. Frontiers in Cellular and Infection Microbiology, 11, 689707. (doi: 10.3389/fcimb.2021.689707) (PMID:34621686) (PMCID:PMC8490869)

Rihn, S. J. et al. (2021) A plasmid DNA-launched SARS-CoV-2 reverse genetics system and coronavirus toolkit for COVID-19 research. PLoS Biology, 19(2), e3001091. (doi: 10.1371/journal.pbio.3001091) (PMID:33630831) (PMCID:PMC7906417)

Stokes, S., Almire, F., Tatham, M. H., McFarlane, S., Mertens, P., Pondeville, E. and Boutell, C. (2020) The SUMOylation pathway suppresses arbovirus replication in Aedes aegypti cells. PLoS Pathogens, 16(12), e1009134. (doi: 10.1371/journal.ppat.1009134) (PMID:33351855) (PMCID:PMC7802965)

McFarlane, S. et al. (2019) The histone chaperone HIRA promotes the induction of host innate immune defences in response to HSV-1 infection. PLoS Pathogens, 15(3), e1007667. (doi: 10.1371/journal.ppat.1007667) (PMID:30901352) (PMCID:PMC6472835)

Alandijany, T., Roberts, A. P.E., Conn, K. L., Loney, C. , McFarlane, S., Orr, A. and Boutell, C. (2018) Distinct temporal roles for the promyelocytic leukaemia (PML) protein in the sequential regulation of intracellular host immunity to HSV-1 infection. PLoS Pathogens, 14(1), e1006769. (doi: 10.1371/journal.ppat.1006769) (PMID:29309427) (PMCID:PMC5757968)

Brown, J. R., Conn, K. L., Wasson, P., Charman, M., Tong, L., Grant, K., McFarlane, S. and Boutell, C. (2016) The SUMO Ligase Protein Inhibitor of Activated STAT 1 (PIAS1) is a constituent PML-NB protein that contributes to the intrinsic antiviral immune response to herpes simplex virus 1 (HSV-1). Journal of Virology, 90, 13. (doi: 10.1128/JVI.00426-16) (PMID:27099310) (PMCID:PMC4907222)

Conn, K. L., Wasson, P., McFarlane, S., Tong, L., Brown, J. R., Grant, K. G., Domingues, P. and Boutell, C. (2016) A novel role for Protein Inhibitor of Activated STAT 4 (PIAS4) in the restriction of herpes simplex virus 1 (HSV-1) by the cellular intrinsic antiviral immune response. Journal of Virology, 90(9), pp. 4807-4826. (doi: 10.1128/JVI.03055-15) (PMID:26937035)

Boutell, C. , Cuchet, D., Vanni, E., Orr, A., Glass, M., McFarlane, S. and Everett, R.D. (2011) A viral ubiquitin ligase has substrate preferential SUMO targeted ubiquitin ligase activity that counteracts intrinsic antiviral defence. PLoS Pathogens, 7(9), e1002245. (doi: 10.1371/journal.ppat.1002245) (PMID:21949651) (PMCID:PMC3174244)

This list was generated on Thu Nov 21 04:58:59 2024 GMT.

Research datasets

Jump to: 2020
Number of items: 1.

2020

Stokes, S., Almire, F., Tatham, M., McFarlane, S., Mertens, P., Pondeville, E. and Boutell, C. (2020) The SUMOylation pathway suppresses arbovirus replication in Aedes aegypti cells. [Data Collection]

This list was generated on Thu Nov 21 12:05:25 2024 GMT.