Dr Mahmood Alam
- Lecturer (Immunology & Infection)
telephone:
0141 330 6685
email:
Mahmood.Alam@glasgow.ac.uk
B223, Sir Graeme Davies Building, 120 University Place, University of Glasgow, Glasgow, G12 8TA
Publications
2024
Sherry, L. , Alam, M. , Mcgregor, A. and Stubbs, F. (2024) Flash Talk: LinkedIn To Get In: Evaluating the Impact of LinkedIn Groups on Undergraduate Career Awareness and Confidence in Networking. Microbiology Society Annual Conference 2024, Edinburgh, UK, 08-11 Apr 2024.
2023
Gill, R., Hora, R., Alam, M. M. , Bansal, A., Bhatt, T. K. and Sharma, A. (2023) Editorial: frontiers in malaria research. Frontiers in Microbiology, 14, 1191773. (doi: 10.3389/fmicb.2023.1191773) (PMID:37077247) (PMCID:PMC10109456)
2020
Mahindra, A., Janha, O., Mapesa, K., Sanchez Azqueta, A., Alam, M. M. , Amambua-Ngwa, A., Nwakanma, D. C., Tobin, A. B. and Jamieson, A. G. (2020) Development of potent PfCLK3 inhibitors based on TCMDC-135051 as a new class of antimalarials. Journal of Medicinal Chemistry, 63(17), pp. 9300-9315. (doi: 10.1021/acs.jmedchem.0c00451) (PMID:32787140) (PMCID:PMC7497403)
2019
Alam, M. M. et al. (2019) Validation of the protein kinase PfCLK3 as a multistage cross-species malarial drug target. Science, 365(6456), eaau1682. (doi: 10.1126/science.aau1682) (PMID:31467193)
2015
Mitcheson, D. F., Tobin, A. B. and Alam, M. M. (2015) Applying chemical genetic tools to the study of phospho-signalling pathways in malaria parasites. Biochimica et Biophysica Acta: Proteins and Proteomics, 1854(10), pp. 1650-1656. (doi: 10.1016/j.bbapap.2015.06.014) (PMID:26143498)
Alam, M. M. et al. (2015) Phosphoproteomics reveals malaria parasite Protein Kinase G as a signalling hub regulating egress and invasion. Nature Communications, 6, 7285. (doi: 10.1038/ncomms8285) (PMID:26149123) (PMCID:PMC4507021)
2014
Kern, S. et al. (2014) Inhibition of the SR protein-phosphorylating CLK kinases of plasmodium falciparum impairs blood stage replication and malaria transmission. PLoS ONE, 9(9), e105732. (doi: 10.1371/journal.pone.0105732) (PMID:25188378) (PMCID:PMC415485)
Graciotti, M., Alam, M. , Solyakov, L., Schmid, R., Burley, G., Bottrill, A. R., Doerig, C., Cullis, P. and Tobin, A. B. (2014) Malaria protein kinase CK2 (PfCK2) shows novel mechanisms of regulation. PLoS ONE, 9(3), e85391. (doi: 10.1371/journal.pone.0085391) (PMID:24658579) (PMCID:PMC3962329)
2012
Lasonder, E., Treeck, M., Alam, M. and Tobin, A. B. (2012) Insights into the Plasmodium falciparum schizont phospho-proteome. Microbes and Infection, 14(10), pp. 811-819. (doi: 10.1016/j.micinf.2012.04.008) (PMID:22569589)
2011
Solyakov, L. et al. (2011) Global kinomic and phospho-proteomic analyses of the human malaria parasite Plasmodium falciparum. Nature Communications, 2, 565. (doi: 10.1038/ncomms1558) (PMID:22127061)
2010
Srivastava, A., Singh, S., Dhawan, S., Alam, M. M. , Mohmmed, A. and Chitnis, C. E. (2010) Localization of apical sushi protein in Plasmodium falciparum merozoites. Molecular and Biochemical Parasitology, 174(1), pp. 66-69. (doi: 10.1016/j.molbiopara.2010.06.003) (PMID:20540969)
Blackman, M. J., Singh, S., Alam, M. M. , Pal-Bhowmick, I., Brzostowski, J. A. and Chitnis, C. E. (2010) Distinct external signals trigger sequential release of apical organelles during erythrocyte invasion by malaria parasites. PLoS Pathogens, 6(2), e1000746. (doi: 10.1371/journal.ppat.1000746) (PMID:20140184) (PMCID:PMC2816683)
2006
Kumar, A., John, L., Alam, M. M. , Gupta, A., Sharma, G., Pillai, B. and Sengupta, S. (2006) Homocysteine- and cysteine-mediated growth defect is not associated with induction of oxidative stress response genes in yeast. Biochemical Journal, 396(1), pp. 61-69. (doi: 10.1042/BJ20051411) (PMID:16433631) (PMCID:PMC1449999)
Articles
Gill, R., Hora, R., Alam, M. M. , Bansal, A., Bhatt, T. K. and Sharma, A. (2023) Editorial: frontiers in malaria research. Frontiers in Microbiology, 14, 1191773. (doi: 10.3389/fmicb.2023.1191773) (PMID:37077247) (PMCID:PMC10109456)
Mahindra, A., Janha, O., Mapesa, K., Sanchez Azqueta, A., Alam, M. M. , Amambua-Ngwa, A., Nwakanma, D. C., Tobin, A. B. and Jamieson, A. G. (2020) Development of potent PfCLK3 inhibitors based on TCMDC-135051 as a new class of antimalarials. Journal of Medicinal Chemistry, 63(17), pp. 9300-9315. (doi: 10.1021/acs.jmedchem.0c00451) (PMID:32787140) (PMCID:PMC7497403)
Alam, M. M. et al. (2019) Validation of the protein kinase PfCLK3 as a multistage cross-species malarial drug target. Science, 365(6456), eaau1682. (doi: 10.1126/science.aau1682) (PMID:31467193)
Mitcheson, D. F., Tobin, A. B. and Alam, M. M. (2015) Applying chemical genetic tools to the study of phospho-signalling pathways in malaria parasites. Biochimica et Biophysica Acta: Proteins and Proteomics, 1854(10), pp. 1650-1656. (doi: 10.1016/j.bbapap.2015.06.014) (PMID:26143498)
Alam, M. M. et al. (2015) Phosphoproteomics reveals malaria parasite Protein Kinase G as a signalling hub regulating egress and invasion. Nature Communications, 6, 7285. (doi: 10.1038/ncomms8285) (PMID:26149123) (PMCID:PMC4507021)
Kern, S. et al. (2014) Inhibition of the SR protein-phosphorylating CLK kinases of plasmodium falciparum impairs blood stage replication and malaria transmission. PLoS ONE, 9(9), e105732. (doi: 10.1371/journal.pone.0105732) (PMID:25188378) (PMCID:PMC415485)
Graciotti, M., Alam, M. , Solyakov, L., Schmid, R., Burley, G., Bottrill, A. R., Doerig, C., Cullis, P. and Tobin, A. B. (2014) Malaria protein kinase CK2 (PfCK2) shows novel mechanisms of regulation. PLoS ONE, 9(3), e85391. (doi: 10.1371/journal.pone.0085391) (PMID:24658579) (PMCID:PMC3962329)
Lasonder, E., Treeck, M., Alam, M. and Tobin, A. B. (2012) Insights into the Plasmodium falciparum schizont phospho-proteome. Microbes and Infection, 14(10), pp. 811-819. (doi: 10.1016/j.micinf.2012.04.008) (PMID:22569589)
Solyakov, L. et al. (2011) Global kinomic and phospho-proteomic analyses of the human malaria parasite Plasmodium falciparum. Nature Communications, 2, 565. (doi: 10.1038/ncomms1558) (PMID:22127061)
Srivastava, A., Singh, S., Dhawan, S., Alam, M. M. , Mohmmed, A. and Chitnis, C. E. (2010) Localization of apical sushi protein in Plasmodium falciparum merozoites. Molecular and Biochemical Parasitology, 174(1), pp. 66-69. (doi: 10.1016/j.molbiopara.2010.06.003) (PMID:20540969)
Blackman, M. J., Singh, S., Alam, M. M. , Pal-Bhowmick, I., Brzostowski, J. A. and Chitnis, C. E. (2010) Distinct external signals trigger sequential release of apical organelles during erythrocyte invasion by malaria parasites. PLoS Pathogens, 6(2), e1000746. (doi: 10.1371/journal.ppat.1000746) (PMID:20140184) (PMCID:PMC2816683)
Kumar, A., John, L., Alam, M. M. , Gupta, A., Sharma, G., Pillai, B. and Sengupta, S. (2006) Homocysteine- and cysteine-mediated growth defect is not associated with induction of oxidative stress response genes in yeast. Biochemical Journal, 396(1), pp. 61-69. (doi: 10.1042/BJ20051411) (PMID:16433631) (PMCID:PMC1449999)
Conference or Workshop Item
Sherry, L. , Alam, M. , Mcgregor, A. and Stubbs, F. (2024) Flash Talk: LinkedIn To Get In: Evaluating the Impact of LinkedIn Groups on Undergraduate Career Awareness and Confidence in Networking. Microbiology Society Annual Conference 2024, Edinburgh, UK, 08-11 Apr 2024.