2024

Sheokand, P. K., Pradhan, S., MacLean, A. E., Mühleip, A. and Sheiner, L. (2024) Plasmodium falciparum mitochondrial complex III, the target of atovaquone, is essential for progression to the transmissible sexual stages. International Journal of Molecular Sciences, 25(17), 9239. (doi: 10.3390/ijms25179239)

Maclean, A. E., Sloan, M. A. , Renaud, E. A., Argyle, B. E., Lewis, W. H., Ovciarikova, J., Demolombe, V., Waller, R. F., Besteiro, S. and Sheiner, L. (2024) The Toxoplasma gondii mitochondrial transporter ABCB7L is essential for the biogenesis of cytosolic and nuclear iron-sulfur cluster proteins and cytosolic translation. mBio, (doi: 10.1128/mbio.00872-24) (PMID:39207139) (Early Online Publication)

Ovciarikova, J. et al. (2024) Two ancient membrane pores mediate mitochondrial-nucleus membrane contact sites. Journal of Cell Biology, 223(4), e202304075. (doi: 10.1083/jcb.202304075) (PMID:38456969)

2023

F. Silva, M., Douglas, K., Sandalli, S., MacLean, A. E. and Sheiner, L. (2023) Functional and biochemical characterization of the Toxoplasma gondii succinate dehydrogenase complex. PLoS Pathogens, 19(12), e1011867. (doi: 10.1371/journal.ppat.1011867) (PMID:38079448) (PMCID:PMC10735183)

2022

MacLean, A. E., Hayward, J. A., Huet, D., van Dooren, G. G. and Sheiner, L. (2022) The mystery of massive mitochondrial complexes: the apicomplexan respiratory chain. Trends in Parasitology, 38(12), pp. 1041-1052. (doi: 10.1016/j.pt.2022.09.008) (PMID:36302692) (PMCID:PMC10434753)

Przybyla-Toscano, J., MacLean, A. E., Franceschetti, M., Liebsch, D., Vignols, F., Keech, O., Rouhier, N. and Balk, J. (2022) Protein lipoylation in mitochondria requires Fe–S cluster assembly factors NFU4 and NFU5. Plant Physiology, 188(2), pp. 997-1013. (doi: 10.1093/plphys/kiab501) (PMID:34718778) (PMCID:PMC8825329)

2021

Moseler, A. et al. (2021) The function of glutaredoxin GRXS15 is required for lipoyl-dependent dehydrogenases in mitochondria. Plant Physiology, 186(3), pp. 1507-1525. (doi: 10.1093/plphys/kiab172) (PMID:33856472)

Kimonis, V. et al. (2021) NUBPL mitochondrial disease: new patients and review of the genetic and clinical spectrum. Journal of Medical Genetics, 58(5), pp. 314-325. (doi: 10.1136/jmedgenet-2020-106846) (PMID:32518176)

Maclean, A. E., Bridges, H. R., F. Silva, M., Ding, S., Ovciarikova, J., Hirst, J. and Sheiner, L. (2021) Complexome profile of Toxoplasma gondii mitochondria identifies divergent subunits of respiratory chain complexes including new subunits of cytochrome bc1 complex. PLoS Pathogens, 17(3), e1009301. (doi: 10.1371/journal.ppat.1009301) (PMID:33651838) (PMCID:PMC7987180)

2019

Lacombe, A., Maclean, A. E., Ovciarikova, J., Tottey, J., Mühleip, A., Fernandes, P. and Sheiner, L. (2019) Identification of the Toxoplasma gondii mitochondrial ribosome, and characterisation of a protein essential for mitochondrial translation. Molecular Microbiology, 112(4), pp. 1235-1252. (doi: 10.1111/mmi.14357) (PMID:31339607) (PMCID:PMC6851545)

2018

MacLean, A. E., Kimonis, V. E. and Balk, J. (2018) Pathogenic mutations in NUBPL affect complex I activity and cold tolerance in the yeast model Yarrowia lipolytica. Human Molecular Genetics, 27(21), pp. 3697-3709. (doi: 10.1093/hmg/ddy247) (PMID:29982452) (PMCID:PMC6196649)

Bastow, E. L., Garcia de la Torre, V. S., MacLean, A. E., Green, R. T., Merlot, S., Thomine, S. and Balk, J. (2018) Vacuolar iron stores gated by NRAMP3 and NRAMP4 are the primary source of iron in germinating seeds. Plant Physiology, 177(3), pp. 1267-1276. (doi: 10.1104/pp.18.00478) (PMID:29784767)

MacLean, A. E., Hertle, A. P., Ligas, J., Bock, R., Balk, J. and Meyer, E. H. (2018) Absence of complex I Is associated with diminished respiratory chain function in European mistletoe. Current Biology, 28(10), 1614-1619.e3. (doi: 10.1016/j.cub.2018.03.036) (PMID:29731304)

Kruse, I., MacLean, A. E., Hill, L. and Balk, J. (2018) Genetic dissection of cyclic pyranopterin monophosphate biosynthesis in plant mitochondria. Biochemical Journal, 475(2), pp. 495-509. (doi: 10.1042/BCJ20170559) (PMID:29247140) (PMCID:PMC5791162)

Articles

Sheokand, P. K., Pradhan, S., MacLean, A. E., Mühleip, A. and Sheiner, L. (2024) Plasmodium falciparum mitochondrial complex III, the target of atovaquone, is essential for progression to the transmissible sexual stages. International Journal of Molecular Sciences, 25(17), 9239. (doi: 10.3390/ijms25179239)

Maclean, A. E., Sloan, M. A. , Renaud, E. A., Argyle, B. E., Lewis, W. H., Ovciarikova, J., Demolombe, V., Waller, R. F., Besteiro, S. and Sheiner, L. (2024) The Toxoplasma gondii mitochondrial transporter ABCB7L is essential for the biogenesis of cytosolic and nuclear iron-sulfur cluster proteins and cytosolic translation. mBio, (doi: 10.1128/mbio.00872-24) (PMID:39207139) (Early Online Publication)

Ovciarikova, J. et al. (2024) Two ancient membrane pores mediate mitochondrial-nucleus membrane contact sites. Journal of Cell Biology, 223(4), e202304075. (doi: 10.1083/jcb.202304075) (PMID:38456969)

F. Silva, M., Douglas, K., Sandalli, S., MacLean, A. E. and Sheiner, L. (2023) Functional and biochemical characterization of the Toxoplasma gondii succinate dehydrogenase complex. PLoS Pathogens, 19(12), e1011867. (doi: 10.1371/journal.ppat.1011867) (PMID:38079448) (PMCID:PMC10735183)

MacLean, A. E., Hayward, J. A., Huet, D., van Dooren, G. G. and Sheiner, L. (2022) The mystery of massive mitochondrial complexes: the apicomplexan respiratory chain. Trends in Parasitology, 38(12), pp. 1041-1052. (doi: 10.1016/j.pt.2022.09.008) (PMID:36302692) (PMCID:PMC10434753)

Przybyla-Toscano, J., MacLean, A. E., Franceschetti, M., Liebsch, D., Vignols, F., Keech, O., Rouhier, N. and Balk, J. (2022) Protein lipoylation in mitochondria requires Fe–S cluster assembly factors NFU4 and NFU5. Plant Physiology, 188(2), pp. 997-1013. (doi: 10.1093/plphys/kiab501) (PMID:34718778) (PMCID:PMC8825329)

Moseler, A. et al. (2021) The function of glutaredoxin GRXS15 is required for lipoyl-dependent dehydrogenases in mitochondria. Plant Physiology, 186(3), pp. 1507-1525. (doi: 10.1093/plphys/kiab172) (PMID:33856472)

Kimonis, V. et al. (2021) NUBPL mitochondrial disease: new patients and review of the genetic and clinical spectrum. Journal of Medical Genetics, 58(5), pp. 314-325. (doi: 10.1136/jmedgenet-2020-106846) (PMID:32518176)

Maclean, A. E., Bridges, H. R., F. Silva, M., Ding, S., Ovciarikova, J., Hirst, J. and Sheiner, L. (2021) Complexome profile of Toxoplasma gondii mitochondria identifies divergent subunits of respiratory chain complexes including new subunits of cytochrome bc1 complex. PLoS Pathogens, 17(3), e1009301. (doi: 10.1371/journal.ppat.1009301) (PMID:33651838) (PMCID:PMC7987180)

Lacombe, A., Maclean, A. E., Ovciarikova, J., Tottey, J., Mühleip, A., Fernandes, P. and Sheiner, L. (2019) Identification of the Toxoplasma gondii mitochondrial ribosome, and characterisation of a protein essential for mitochondrial translation. Molecular Microbiology, 112(4), pp. 1235-1252. (doi: 10.1111/mmi.14357) (PMID:31339607) (PMCID:PMC6851545)

MacLean, A. E., Kimonis, V. E. and Balk, J. (2018) Pathogenic mutations in NUBPL affect complex I activity and cold tolerance in the yeast model Yarrowia lipolytica. Human Molecular Genetics, 27(21), pp. 3697-3709. (doi: 10.1093/hmg/ddy247) (PMID:29982452) (PMCID:PMC6196649)

Bastow, E. L., Garcia de la Torre, V. S., MacLean, A. E., Green, R. T., Merlot, S., Thomine, S. and Balk, J. (2018) Vacuolar iron stores gated by NRAMP3 and NRAMP4 are the primary source of iron in germinating seeds. Plant Physiology, 177(3), pp. 1267-1276. (doi: 10.1104/pp.18.00478) (PMID:29784767)

MacLean, A. E., Hertle, A. P., Ligas, J., Bock, R., Balk, J. and Meyer, E. H. (2018) Absence of complex I Is associated with diminished respiratory chain function in European mistletoe. Current Biology, 28(10), 1614-1619.e3. (doi: 10.1016/j.cub.2018.03.036) (PMID:29731304)

Kruse, I., MacLean, A. E., Hill, L. and Balk, J. (2018) Genetic dissection of cyclic pyranopterin monophosphate biosynthesis in plant mitochondria. Biochemical Journal, 475(2), pp. 495-509. (doi: 10.1042/BCJ20170559) (PMID:29247140) (PMCID:PMC5791162)