2023

Lowe, G., Wu, O. , van Hylckama Vlieg, A., Folsom, A., Rosendaal, F. and Woodward, M. (2023) Plasma levels of coagulation factors VIII and IX and risk of venous thromboembolism: systematic review and meta-analysis. Thrombosis Research, 229, pp. 31-39. (doi: 10.1016/j.thromres.2023.06.026)

2022

Lowe, G., Peters, S. A.E., Rumley, A., Tunstall-Pedoe, H. and Woodward, M. (2022) Associations of haemostatic variables with cardiovascular disease and total mortality - the Glasgow MONICA Study. TH Open, 6(2), e107-e113. (doi: 10.1055/a-1789-4896)

Wannamethee, S. G., Papacosta, O., Lennon, L., Whincup, P. H., Rumley, A. and Lowe, G. D.O. (2022) Haematological variables and risk of future venous thromboembolism in the British Regional Heart Study on men. Combined D‐dimer and APTT as a predictive test for thromboembolism? British Journal of Haematology, (doi: 10.1111/bjh.18288) (PMID:35655415)

Lowe, G. (2022) Thrombosis in Scotland, 1800–1960. Journal of the Royal College of Physicians of Edinburgh, 52(2), pp. 153-158. (doi: 10.1177/14782715221107949)

2021

Lowe, G. (2021) The birth of British geriatric medicine: further information on Scotland. Journal of the Royal College of Physicians of Edinburgh, 51(4), pp. 424-427. (doi: 10.4997/JRCPE.2021.427) (PMID:34882152)

2019

Kitas, G. D. et al. (2019) A multicenter, randomized, placebo‐controlled trial of atorvastatin for the primary prevention of cardiovascular events in patients with rheumatoid arthritis. Arthritis and Rheumatology, 71(9), pp. 1437-1449. (doi: 10.1002/art.40892) (PMID:30983166) (PMCID:PMC6771601)

Gregson, J. et al. (2019) Cardiovascular risk factors associated with venous thromboembolism. JAMA Cardiology, 4(2), pp. 163-173. (doi: 10.1001/jamacardio.2018.4537) (PMID:30649175) (PMCID:PMC6386140)

2018

Patterson, C. C., Blankenberg, S., Ben-Shlomo, Y., Heslop, L., Bayer, A., Lowe, G., Zeller, T., Gallacher, J., Young, I. and Yarnell, J. W.G. (2018) Troponin and BNP are markers for subsequent non-ischaemic congestive heart failure: the Caerphilly Prospective Study (CaPS). Open Heart, 5(1), e000692. (doi: 10.1136/openhrt-2017-000692) (PMID:29531757) (PMCID:PMC5845403)

Spronk, H. et al. (2018) Atherothrombosis and thromboembolism: position paper from the Second Maastricht consensus Conference on thrombosis. Thrombosis and Haemostasis, 118(2), pp. 229-250. (doi: 10.1160/th17-07-0492) (PMID:29378352)

Lowe, G. D.O. (2018) Self-related health and blood hypercoagulability: a possible mechanism for cardiovascular risk. Thrombosis and Haemostasis, 118(1), pp. 4-5. (doi: 10.1160/th17-11-0836) (PMID:29304521)

2017

Sartini, C., Whincup, P. H., Wannamethee, S. G., Jefferis, B. J., Lennon, L., Lowe, G. D.O., Welsh, P. , Sattar, N. and Morris, R. W. (2017) Associations of time of day with cardiovascular disease risk factors measured in older men: results from the British Regional Heart Study. BMJ Open, 7(11), e018264. (doi: 10.1136/bmjopen-2017-018264) (PMID:29133328) (PMCID:PMC5695475)

Wannamethee, S. G., Whincup, P. H., Papacosta, O., Lennon, L. and Lowe, G. D. (2017) Associations between blood coagulation markers, NT-proBNP and risk of incident heart failure in older men: The British Regional Heart Study. International Journal of Cardiology, 230, pp. 567-571. (doi: 10.1016/j.ijcard.2016.12.056) (PMID:28043678) (PMCID:PMC5267630)

Sartini, C. et al. (2017) Relationship between outdoor temperature and cardiovascular disease risk factors in older people. European Journal of Preventive Cardiology, 24(4), pp. 349-356. (doi: 10.1177/2047487316682119) (PMID:27899528)

de Vries, P. S. et al. (2017) Comparison of HapMap and 1000 genomes reference panels in a large-scale genome-wide association study. PLoS ONE, 12(1), e0167742. (doi: 10.1371/journal.pone.0167742) (PMID:28107422) (PMCID:PMC5249120)

Peters, S. A.E., Woodward, M., Rumley, A., Tunstall-Pedoe, H. D. and Lowe, G. D.O. (2017) Plasma and blood viscosity in the prediction of cardiovascular disease and mortality in the Scottish Heart Health Extended Cohort Study. European Journal of Preventive Cardiology, 24(2), pp. 161-167. (doi: 10.1177/2047487316672004) (PMID:27798361)

2016

Lazzarino, A. I., Hamer, M., Gaze, D., Collinson, P., Rumley, A., Lowe, G. and Steptoe, A. (2016) The interaction between systemic inflammation and psychosocial stress in the association with cardiac troponin elevation: a new approach to risk assessment and disease prevention. Preventive Medicine, 93, pp. 46-52. (doi: 10.1016/j.ypmed.2016.09.018) (PMID:27663429) (PMCID:PMC5126095)

Steptoe, A., Kivimäki, M., Lowe, G., Rumley, A. and Hamer, M. (2016) Blood pressure and fibrinogen responses to mental stress as predictors of incident hypertension over an 8-year period. Annals of Behavioral Medicine, 50(6), pp. 898-906. (doi: 10.1007/s12160-016-9817-5) (PMID:27401000) (PMCID:PMC5126198)

Wang, X., Chappell, F. M., Valdes Hernandez, M., Lowe, G., Rumley, A., Shuler, K., Doubal, F. and Wardlaw, J. M. (2016) Endothelial function, inflammation, thrombosis, and basal ganglia perivascular spaces in patients with stroke. Journal of Stroke and Cerebrovascular Diseases, 25(12), pp. 2925-2931. (doi: 10.1016/j.jstrokecerebrovasdis.2016.08.007) (PMID:27576214) (PMCID:PMC5176093)

Herder, C. et al. (2016) Biomarkers of subclinical inflammation and increases in glycaemia, insulin resistance and beta-cell function in non-diabetic individuals: the Whitehall II study. European Journal of Endocrinology, 175, pp. 367-377. (doi: 10.1530/EJE-16-0528) (PMID:27491375)

van Loon, J. et al. (2016) Genome-wide association studies identify genetic loci for low von Willebrand factor levels. European Journal of Human Genetics, 24(7), pp. 1035-1040. (doi: 10.1038/ejhg.2015.222) (PMID:26486471)

2015

Lazzarino, A.I., Hamer, M., Gaze, D., Collinson, P., Rumley, A., Lowe, G. and Steptoe, A. (2015) The association between fibrinogen reactivity to mental stress and high-sensitivity cardiac troponin T in healthy adults. Psychoneuroendocrinology, 59, pp. 37-48. (doi: 10.1016/j.psyneuen.2015.05.002) (PMID:26010862)

Wiseman, S. J., Doubal, F. N., Chappell, F. M., Valdés-Hernández, M. C., Wang, X., Rumley, A., Lowe, G. D.O., Dennis, M. S. and Wardlaw, J. M. (2015) Plasma biomarkers of inflammation, endothelial function andhemostasis in cerebral small vessel disease. Cerebrovascular Diseases, 40(3-4), pp. 157-164. (doi: 10.1159/000438494) (PMID:26279056)

Maino, A., Siegerink, B., Lotta, L.A., Crawley, J.T.B., le Cessie, S., Leebeek, F.W.G., Lane, D. A., Lowe, G.D.O., Peyvandi, F. and Rosendaal, F.R. (2015) Plasma ADAMTS-13 levels and the risk of myocardial infarction: an individual patient data meta-analysis. Journal of Thrombosis and Haemostasis, 13(8), pp. 1396-1404. (doi: 10.1111/jth.13032) (PMID:26073931)

Virtanen, M. et al. (2015) Interleukin-6 as a predictor of symptom resolution in psychological distress: a cohort study. Psychological Medicine, 45(10), pp. 2137-2144. (doi: 10.1017/S0033291715000070) (PMID:25697833)

Akbaraly, T. N., Shipley, M. J., Ferrie, J. E., Virtanen, M., Lowe, G., Hamer, M. and Kivimaki, M. (2015) Long-term adherence to healthy dietary guidelines and chronic inflammation in the prospective Whitehall II study. American Journal of Medicine, 128(2), 152-160.e4. (doi: 10.1016/j.amjmed.2014.10.002)

Loeffen, R., Winckers, K., Ford, I. , Jukema, J. W., Robertson, M., Stott, D. J. , Spronk, H. M., ten Cate, H. and Lowe, G. (2015) Associations between thrombin generation and the risk of cardiovascular disease in elderly patients: results from the PROSPER study. Journals of Gerontology Series A: Biological Sciences and Medical Sciences, 70(8), pp. 982-988. (doi: 10.1093/gerona/glu228) (PMID:25540034)

2014

Wannamethee, S. G., Whincup, P. H., Lennon, L., Papacosta, O. and Lowe, G. D. (2014) Associations between fibrin D-dimer, markers of inflammation, incident self-reported mobility limitation, and all-cause mortality in older men. Journal of the American Geriatrics Society, 62(12), pp. 2357-2362. (doi: 10.1111/jgs.13133)

Lowe, G. and Rumley, A. (2014) The relevance of coagulation in cardiovascular disease: what do the biomarkers tell us? Thrombosis and Haemostasis, 112(5), pp. 860-867. (doi: 10.1160/TH14-03-0199)

ten Cate, H. and Lowe, G. (2014) Coagulation proteases and cardiovascular disease. Thrombosis and Haemostasis, 112(5), pp. 858-859. (doi: 10.1160/TH14-09-0781)

Cheng, K., Giebaly, D., Campbell, A., Rumley, A. and Lowe, G. (2014) Systemic effects of polymethylmethycrylate in total knee replacement: a prospective case-control study. Bone and Joint Research, 3(4), pp. 108-116. (doi: 10.1302/2046-3758.34.2000230) (PMID:24740649) (PMCID:PMC4036303)

Lowe, G. et al. (2014) Circulating inflammatory markers and the risk of vascular complications and mortality in people with type 2 diabetes and cardiovascular disease or risk factors: the ADVANCE Study. Diabetes, 63(3), pp. 1115-1123. (doi: 10.2337/db12-1625)

Baumert, J. et al. (2014) No evidence for genome-wide interactions on plasma fibrinogen by smoking, alcohol consumption and body mass index: results from meta-analyses of 80,607 subjects. PLoS ONE, 9(12), e111156. (doi: 10.1371/journal.pone.0111156) (PMID:25551457) (PMCID:PMC4281156)

Huang, J. et al. (2014) Genome-wide association study for circulating tissue plasminogen activator levels and functional follow-up implicates endothelial STXBP5 and STX2. Arteriosclerosis, Thrombosis, and Vascular Biology, 34(5), pp. 1093-1101. (doi: 10.1161/ATVBAHA.113.302088)

Kivimäki, M. et al. (2014) Long-term inflammation increases risk of common mental disorder: a cohort study. Molecular Psychiatry, 19(2), pp. 149-150. (doi: 10.1038/mp.2013.35)

Lowe, G. and Bagot, C. (2014) Hemostasis and thrombosis. In: Baynes, J.W. and Dominiczak, M. (eds.) Medical Biochemistry [4th ed.]. Saunders/Elsevier: Edinburgh, pp. 68-81. ISBN 9781455745807

Tabassum, F., Kumari, M., Rumley, A., Power, C., Strachan, D. P. and Lowe, G. (2014) Lifecourse social position and D-dimer; findings from the 1958 British birth cohort. PLoS ONE, 9(5), e93277. (doi: 10.1371/journal.pone.0093277) (PMID:24809471) (PMCID:PMC4014469)

2013

Gaunt, T.R. et al. (2013) Gene-centric association signals for haemostasis and thrombosis traits identified with the HumanCVD BeadChip. Thrombosis and Haemostasis, 110(5), pp. 995-1003. (doi: 10.1160/TH13-02-0087)

Khan, M.M., Tait, R.C. , Kerr, R., Ludlam, C.A., Lowe, G.D.O., Murray, W. and Watson, H.G. (2013) Hepatitis C infection and outcomes in the Scottish haemophilia population. Haemophilia, 19(6), pp. 870-875. (doi: 10.1111/hae.12218) (PMID:23786361)

Peters, S.A.E., Woodward, M., Rumley, A., Koenig, W., Tunstall-Pedoe, H. and Lowe, G.D.O. (2013) Direct comparisons of three alternative plasma fibrinogen assays with the von Clauss assay in prediction of cardiovascular disease and all-causes mortality: the Scottish heart health extended cohort. British Journal of Haematology, 162(3), pp. 392-399. (doi: 10.1111/bjh.12389)

Smid, M., Dielis, A. W. J. H., Spronk, H. M. H. S., Rumley, A., van Oerle, R., Woodward, M., ten Cate, H. and Lowe, G. (2013) Thrombin generation in the Glasgow myocardial infarction study. PLoS ONE, 8(6), e66977. (doi: 10.1371/journal.pone.0066977) (PMID:23826181) (PMCID:PMC3691168)

Gaunt, T.R., Lowe, G.D.O., Lawlor, D.A., Casas, J.-P. and Day, I.N.M. (2013) A gene-centric analysis of activated partial thromboplastin time and activated protein C resistance using the HumanCVD focused genotyping array. European Journal of Human Genetics, 21(7), pp. 779-783. (doi: 10.1038/ejhg.2012.242)

Inglis, S.C., Lewsey, J.D. , Lowe, G.D.O., Jhund, P. , Gillies, M., Stewart, S., Capewell, S., MacIntyre, K. and McMurray, J.J.V. (2013) Angina and intermittent claudication in 7403 participants of the 2003 Scottish Health Survey: impact on general and mental health, quality of life and five-year mortality. International Journal of Cardiology, 167(5), pp. 2149-2155. (doi: 10.1016/j.ijcard.2012.05.099)

Willeit, P., Thompson, A., Aspelund, T., Rumley, A., Eiriksdottir, G., Lowe, G., Gudnason, V. and Di Angelantonio, E. (2013) Hemostatic factors and risk of coronary heart disease in general populations: new prospective study and updated meta-analyses. PLoS ONE, 8(2), e55175. (doi: 10.1371/journal.pone.0055175) (PMID:23408959) (PMCID:PMC3567058)

2012

Kaptoge, S. et al. (2012) C-reactive protein, fibrinogen, and cardiovascular disease prediction. New England Journal of Medicine, 367(14), pp. 1310-1320. (doi: 10.1056/NEJMoa1107477)

Lowe, G.D.O. (2012) Epidemiology of venous thromboembolism: the need for large (including prospective) studies and meta-analyses. Journal of Thrombosis and Haemostasis, 10(10), pp. 2186-2188. (doi: 10.1111/j.1538-7836.2012.04882.x)

Hingorani, A.D., Sofat, R., Morris, R.W., Whincup, P., Lowe, G.D., Mindell, J., Sattar, N. , Casas, J.P. and Shah, T. (2012) Is it important to measure or reduce C-reactive protein in people at risk of cardiovascular disease? European Heart Journal, 33(18), pp. 2258-2264. (doi: 10.1093/eurheartj/ehs168)

Paul, L. et al. (2012) Hematocrit predicts long-term mortality in a nonlinear and sex-specific manner in hypertensive adults. Hypertension, 60(3), pp. 631-638. (doi: 10.1161/HYPERTENSIONAHA.112.191510)

Inglis, S.C., Lewsey, J.D. , Chandler, D., Byrne, D.S., Lowe, G.D.O. and MacIntyre, K. (2012) Sex-specific time trends in first admission to hospital for peripheral artery disease in Scotland 1991-2007. British Journal of Surgery, 99(5), pp. 680-687. (doi: 10.1002/bjs.8686)

Ghebre, M.A., Wannamethee, S.G., Rumley, A., Whincup, P.H., Lowe, G.D.O. and Morris, R.W. (2012) Prospective study of seasonal patterns in hemostatic factors in older men and their relation to excess winter coronary heart disease deaths. Journal of Thrombosis and Haemostasis, 10(3), pp. 352-358. (doi: 10.1111/j.1538-7836.2012.04617.x)

Wannamethee, S.G., Papacosta, O., Lawlor, D.A., Whincup, P.H., Lowe, G.D., Ebrahim, S. and Sattar, N. (2012) Do women exhibit greater differences in established and novel risk factors between diabetes and non-diabetes than men? The British Regional Heart Study and British Women’s Heart Health Study. Diabetologia, 55(1), pp. 80-87. (doi: 10.1007/s00125-011-2284-4)

Wennberg, P., Wensley, F., Di Angelantonio, E., Johansson, L., Boman, K., Rumley, A., Lowe, G., Hallmans, G., Danesh, J. and Jansson, J.-H. (2012) Haemostatic and inflammatory markers are independently associated with myocardial infarction in men and women. Thrombosis Research, 129(1), pp. 68-73. (doi: 10.1016/j.thromres.2011.05.015)

Nüesch, E., Dale, C.E., Amuzu, A., Kuper, H., Bowling, A., Ploubidis, G.B., Lowe, G., Rumley, A., Ebrahim, S. and Casas, J.P. (2012) Inflammation, coagulation and risk of locomotor disability in elderly women: findings from the British Women’s Heart and Health Study. European Journal of Epidemiology, 27(8), pp. 633-645. (doi: 10.1007/s10654-012-9706-6)

Whiteley, W., Wardlaw, J., Dennis, M., Lowe, G., Rumley, A., Sattar, N. , Welsh, P. , Green, A., Andrews, M. and Sandercock, P. (2012) The use of blood biomarkers to predict poor outcome after acute transient ischemic attack or ischemic stroke. Stroke, 43(1), pp. 86-91. (doi: 10.1161/STROKEAHA.111.634089)

2011

Marioni, R.E. et al. (2011) Genetic associations between fibrinogen and cognitive performance in three Scottish cohorts. Behavior Genetics, 41(5), pp. 691-699. (doi: 10.1007/s10519-011-9449-2)

Jefferis, B.J., Whincup, P.H., Welsh, P. , Wannathamee, S.G., Rumley, A., Lawlor, D.A., Ebrahim, S. and Lowe, G.D.O. (2011) Prospective study of circulating soluble CD40 ligand concentrations and the incidence of cardiovascular disease in a nested prospective case-control study of older men and women. Journal of Thrombosis and Haemostasis, 9(8), pp. 1452-1459. (doi: 10.1111/j.1538-7836.2011.04415.x)

Quinn, T.J. , Gallacher, J., Deary, I.J., Lowe, G.D.O., Fenton, C. and Stott, D.J. (2011) Association between circulating hemostatic measures and dementia or cognitive impairment: systematic review and meta-analyzes. Journal of Thrombosis and Haemostasis, 9(8), pp. 1475-1482. (doi: 10.1111/j.1538-7836.2011.04403.x)

Wannamethee, S. G., Welsh, P. , Lowe, G. D., Gudnason, V., Di Angelantonio, E., Lennon, L., Rumley, A., Whincup, P. H. and Sattar, N. (2011) N-terminal pro-brain natriuretic peptide is a more useful predictor of cardiovascular disease risk than C-reactive protein in older men with and without pre-existing cardiovascular disease. Journal of the American College of Cardiology, 58(1), pp. 56-64. (doi: 10.1016/j.jacc.2011.02.041)

Bolton, C.E. et al. (2011) The CRP genotype, serum levels and lung function in men: the Caerphilly Prospective Study. Clinical Science, 120(8), pp. 347-355. (doi: 10.1042/CS20100504)

Wensley, F. et al. (2011) Association between C reactive protein and coronary heart disease: mendelian randomisation analysis based on individual participant data. British Medical Journal, 342, d548-d548. (doi: 10.1136/bmj.d548)

Calvin, C.M., Batty, G.D., Lowe, G.D.O. and Deary, I.J. (2011) Childhood intelligence and midlife inflammatory and hemostatic biomarkers: The National Child Development Study (1958) cohort. Health Psychology, 30(6), pp. 710-718. (doi: 10.1037/a0023940)

Freeman, D. J. et al. (2011) Incident venous thromboembolic events in the Prospective Study of Pravastatin in the Elderly at Risk (PROSPER). BMC Geriatrics, 11, 8. (doi: 10.1186/1471-2318-11-8) (PMID:21342490) (PMCID:PMC3053238)

Jefferis, B.J.M.H. et al. (2011) Interleukin 18 and coronary heart disease: Prospective study and systematic review. Atherosclerosis, 217(1), pp. 227-233. (doi: 10.1016/j.atherosclerosis.2011.03.015)

Lowe, G. (2011) Can haemostatic factors predict atherothrombosis? Internal and Emergency Medicine, 6(6), pp. 497-501. (doi: 10.1007/s11739-011-0536-4)

Ngai, L.-Y., Stocks, N., Sparrow, J. M., Patel, R., Rumley, A., Lowe, G., Davey Smith, G. and Ben-Shlomo, Y. (2011) The prevalence and analysis of risk factors for age-related macular degeneration: 18-year follow-up data from the Speedwell eye study, United Kingdom. Eye, 25(6), pp. 784-793. (doi: 10.1038/eye.2011.56)

Rudnicka, A.R., Rumley, A., Whincup, P.H., Lowe, G.D. and Strachan, D.P. (2011) Sex differences in the relationship between inflammatory and hemostatic biomarkers and metabolic syndrome: British 1958 Birth Cohort. Journal of Thrombosis and Haemostasis, 9(12), pp. 2337-2344. (doi: 10.1111/j.1538-7836.2011.04517.x)

Smith, N. L. et al. (2011) Genetic predictors of fibrin D-Dimer levels in healthy adults. Circulation, 123(17), pp. 1864-1872. (doi: 10.1161/CIRCULATIONAHA.110.009480)

Stephens, J.W. et al. (2011) Effects of short-term therapy with glibenclamide and repaglinide on incretin hormones and oxidative damage associated with postprandial hyperglycaemia in people with type 2 diabetes mellitus. Diabetes Research and Clinical Practice, 94(2), pp. 199-206. (doi: 10.1016/j.diabres.2011.07.014)

Whiteley, W., Jackson, C., Lewis, S., Lowe, G., Rumley, A., Sandercock, P., Wardlaw, J., Dennis, M. and Sudlow, C. (2011) Association of circulating inflammatory markers with recurrent vascular events after stroke: a prospective cohort study. Stroke, 42(1), pp. 10-16. (doi: 10.1161/STROKEAHA.110.588954)

Whiteley, W. et al. (2011) Blood biomarkers for the diagnosis of acute cerebrovascular diseases: a prospective cohort study. Cerebrovascular Diseases, 32(2), pp. 141-147. (doi: 10.1159/000328517)

Zabaneh, D. et al. (2011) Genetic Variants Associated with von Willebrand Factor Levels in Healthy Men and Women Identified Using the HumanCVD BeadChip. Annals of Human Genetics, 75(4), pp. 456-467. (doi: 10.1111/j.1469-1809.2011.00654.x)

2010

Lowe, G.D. and Sandercock, P. (2010) Does acetyl salicylic acid (ASA) have a role in the prevention of venous thromboembolism? British Journal of Haematology, 148(2), pp. 339-340. (doi: 10.1111/j.1365-2141.2009.07933.x)

Clark, P., Wu, O. , Greer, I.A. and Lowe, G.D.O. (2010) Venous thrombosis prevention more than just guidelines. British Journal of Haematology, 149(1), pp. 50-54. (doi: 10.1111/j.1365-2141.2010.08080.x)

Fogarty, A.W., Lewis, S.A., McKeever, T.M., Lowe, G.D.O., Clark, L., Britton, J. and Reitsma, P.H. (2010) The association between blood coagulation activity and lung function: a population-based study. PLoS ONE, 5(11), e15014. (doi: 10.1371/journal.pone.0015014) (PMID:21103357) (PMCID:PMC2982817)

Gallacher, J., Bayer, A., Lowe, G., Fish, M., Pickering, J., Pedro, S., Dunstan, F., White, J., Yarnell, J. and Ben Shlomo, Y. (2010) Is Sticky Blood Bad for the Brain? Hemostatic and Inflammatory Systems and Dementia in the Caerphilly Prospective Study. Arteriosclerosis, Thrombosis, and Vascular Biology, 30(3), 599-U459. (doi: 10.1161/ATVBAHA.109.197368)

Hamer, M., Stamatakis, E., Kivimaki, M., Lowe, G. D. and Batty, G. D. (2010) Objectively Measured Secondhand Smoke Exposure and Risk of Cardiovascular Disease. Journal of the American College of Cardiology, 56(1), pp. 18-23. (doi: 10.1016/j.jacc.2010.03.032)

Houlihan, L. M. et al. (2010) Common Variants of Large Effect in F12, KNG1, and HRG Are Associated with Activated Partial Thromboplastin Time. American Journal of Human Genetics, 86(4), pp. 626-631. (doi: 10.1016/j.ajhg.2010.02.016)

Jefferis, B. J. et al. (2010) Secondhand smoke (SHS) exposure is associated with circulating markers of inflammation and endothelial function in adult men and women. Atherosclerosis, 208(2), pp. 550-556. (doi: 10.1016/j.atherosclerosis.2009.07.044)

Jefferis, B. J. et al. (2010) Prospective study of matrix metalloproteinase-9 and risk of myocardial infarction and stroke in older men and women. Atherosclerosis, 208(2), pp. 557-563. (doi: 10.1016/j.atherosclerosis.2009.08.018)

Lowe, G. (2010) What is the clinical relevance of the prothrombin G20210A mutation? Atherosclerosis, 208(2), pp. 330-331. (doi: 10.1016/j.atherosclerosis.2009.11.002)

Lowe, G. D. O. (2010) Fibrinogen Assays for Cardiovascular Risk Assessment. Clinical Chemistry, 56(5), pp. 693-695. (doi: 10.1373/clinchem.2010.145342)

Lowe, G. D. O. (2010) Management of deep vein thrombosis to reduce the incidence of post-thrombotic syndrome. Phlebology, 25(Supple), pp. 9-13. (doi: 10.1258/phleb.2010.010s02)

Marioni, R. E., Deary, I. J., Strachan, M. W., Lowe, G. D., Rumley, A., Murray, G. D. and Price, J. F. (2010) Blood rheology and cognition in the Edinburgh Type 2 Diabetes Study. Age and Ageing, 39(3), pp. 354-359. (doi: 10.1093/ageing/afq021)

Marioni, R. E. et al. (2010) Association Between Raised Inflammatory Markers and Cognitive Decline in Elderly People With Type 2 Diabetes The Edinburgh Type 2 Diabetes Study. Diabetes, 59(3), pp. 710-713. (doi: 10.2337/db09-1163)

Marioni, R.E. et al. (2010) Genetic variants associated with altered plasma levels of C-reactive protein are not associated with late-life cognitive ability in four Scottish samples. Behavior Genetics, 40(1), pp. 3-11. (doi: 10.1007/s10519-009-9302-z)

McEniery, C. M., Spratt, M., Munnery, M., Yarnell, J., Lowe, G. D., Rumley, A., Gallacher, J., Ben Shlomo, Y., Cockcroft, J. R. and Wilkinson, I. B. (2010) An Analysis of Prospective Risk Factors for Aortic Stiffness in Men 20-Year Follow-Up From the Caerphilly Prospective Study. Hypertension, 56(1), pp. 36-43. (doi: 10.1161/HYPERTENSIONAHA.110.150896)

Patterson, C. C., Smith, A. E., Yarnell, J. W. G., Rumley, A., Ben Shlomo, Y. and Lowe, G.D.O. (2010) The associations of interleukin-6 (IL-6) and downstream inflammatory markers with risk of cardiovascular disease: The Caerphilly Study. Atherosclerosis, 209(2), pp. 551-557. (doi: 10.1016/j.atherosclerosis.2009.09.030)

Rafnsson, S., Deary, I.J., Whiteman, M.C., Rumley, A., Lowe, G.D.O. and Fowkes, F.G.R. (2010) Haemorheological predictors of cognitive decline: the Edinburgh Artery Study. Age and Ageing, 39(2), pp. 217-222. (doi: 10.1093/ageing/afp227)

Stott, D.J. et al. (2010) Activation of Hemostasis and Decline in Cognitive Function in Older People. Arteriosclerosis, Thrombosis, and Vascular Biology, 30(3), pp. 605-611. (doi: 10.1161/ATVBAHA.109.199448)

Tabak, A. G., Kivimaki, M., Brunner, E. J., Lowe, G.D., Jokela, M., Akbaraly, T. N., Singh-Manoux, A., Ferrie, J. E. and Witte, D. R. (2010) Changes in C-reactive protein levels before type 2 diabetes and cardiovascular death: the Whitehall II study. European Journal of Endocrinology, 163(1), pp. 89-95. (doi: 10.1530/EJE-10-0277)

Wannamethee, S. G., Shaper, A. G., Rumley, A., Sattar, N. , Whincup, P. H., Thomas, M. C. and Lowe, G.D. (2010) Lung Function and Risk of Type 2 Diabetes and Fatal and Nonfatal Major Coronary Heart Disease Events: Possible Associations With Inflammation. Diabetes Care, 33(9), pp. 1990-1996. (doi: 10.2337/dc10-0324)

Weir, R.A.P., Balmain, S., Steedman, T., Ng, L. L., Squire, I. B., Rumley, A., Dargie, H.J. and Lowe, G.D.O. (2010) Tissue plasminogen activator antigen predicts medium-term left ventricular end-systolic volume after acute myocardial infarction. Journal of Thrombosis and Thrombolysis, 29(4), pp. 421-428. (doi: 10.1007/s11239-009-0383-6)

Welsh, P. , Woodward, M., Rumley, A., MacMahon, S. and Lowe, G.D. (2010) Does interleukin-18 or tumour necrosis factor-alpha have an independent association with the risk of coronary heart disease? Results from a prospective study in New Zealand. Cytokine, 50(1), pp. 94-98. (doi: 10.1016/j.cyto.2009.12.014)

Wennberg, P., Wensley, F., Johansson, L., Boman, K., Di Angelantonio, E., Rumley, A., Lowe, G., Hallmans, G. and Jansson, J. H. (2010) Reduced risk of myocardial infarction related to active commuting: inflammatory and haemostatic effects are potential major mediating mechanisms. European Journal of Cardiovascular Prevention and Rehabilitation, 17(1), pp. 56-62. (doi: 10.1097/HJR.0b013e32832f3b11)

Woodward, M., Welsh, P. , Rumley, A., Tunstall-Pedoe, H. and Lowe, G. D. O. (2010) Do inflammatory biomarkers add to the discrimination of cardiovascular disease after allowing for social deprivation? Results from a 10-year cohort study in Glasgow, Scotland. European Heart Journal, 31(21), pp. 2669-2675. (doi: 10.1093/eurheartj/ehp115)

2009

Shepherd, J., Lowe, G., Ford, I. and Robertson, M. (2009) Correcting for multivariate measurement error by regression calibration in meta-analyses of epidemiological studies. Statistics in Medicine, 28(7), pp. 1067-1092. (doi: 10.1002/sim.3530)

Stott, D.J., Welsh, P.I., Rumley, A., Robertson, M., Ford, I. , Sattar, N.A., Westendorp, R.G.J., Jukema, J.W., Cobbe, S. and Lowe, G.D. (2009) Adipocytokines and risk of stroke in older people: a nested case-control study. International Journal of Epidemiology, 38(1), pp. 253-261. (doi: 10.1093/ije/dyn215)

Dehghan, A. et al. (2009) Association of Novel Genetic Loci With Circulating Fibrinogen Levels A Genome-Wide Association Study in 6 Population-Based Cohorts. Circulation: Cardiovascular Genetics, 2(2), 125-U91. (doi: 10.1161/CIRCGENETICS.108.825224)

Fraser, A., May, M., Lowe, G., Rumley, A., Davey Smith, G., Ebrahim, S. and Lawlor, D. (2009) Interleukin-6 and incident coronary heart disease: Results from the British Women's Heart and Health Study. Atherosclerosis, 202(2), pp. 567-572. (doi: 10.1016/j.atherosclerosis.2008.04.048)

Gimeno, D. et al. (2009) Associations of C-reactive protein and interleukin-6 with cognitive symptoms of depression: 12-year follow-up of the Whitehall II study. Psychological Medicine, 39(3), pp. 413-423.

Heikkila, K., Harris, R., Lowe, G., Rumley, A., Yarnell, J., Gallacher, J., Ben Shlomo, Y., Ebrahim, S. and Lawlor, D. (2009) Associations of circulating C-reactive protein and interleukin-6 with cancer risk: findings from two prospective cohorts and a meta-analysis. Cancer Causes and Control, 20(1), pp. 15-26.

Jefferis, B. et al. (2009) Circulating TNF alpha levels in older men and women do not show independent prospective relations with MI or stroke. Atherosclerosis, 205(1), pp. 302-308.

Lowe, G. (2009) Common risk factors for both arterial and venous thrombosis. Sang Thrombose Vaisseaux, 21(1), pp. 31-38.

Marioni, R. et al. (2009) Peripheral Levels of Fibrinogen, C-Reactive Protein, and Plasma Viscosity Predict Future Cognitive Decline in Individuals Without DementiaPeripheral Neuropathies Biomarkers for Axonal Damage in Immune-Mediated Neuropathy. Psychosomatic Medicine, 71(8), pp. 901-906.

Ramsay, S., Morris, R., Whincup, P., Papacosta, O., Rumley, A., Lennon, L., Lowe, G.D. and Wannamethee, S. (2009) Socioeconomic inequalities in coronary heart disease risk in older age: contribution of established and novel coronary risk factors. Journal of Thrombosis and Haemostasis, 7(11), pp. 1779-1786.

Sanders, J., Hawe, E., Brull, D., Hubbart, C., Lowe, G.D., Rumley, A., Humphries, S. and Montgomery, H. (2009) Higher IL-6 levels but not IL6-174G > C or-572G > C genotype are associated with post-operative complication following coronary artery bypass graft (CABG) surgery. Atherosclerosis, 204(1), pp. 196-201.

Sanderson, S., Kumari, M., Brunner, E., Miller, M., Rumley, A., Lowe, G.D., Marmot, M. and Humphries, S. (2009) Association between IL6 gene variants-174G > C and-572G > C and serum IL-6 levels: Interactions with social position in the Whitehall II cohort. Atherosclerosis, 204(2), pp. 459-464.

Sattar, N.A. et al. (2009) Are markers of inflammation more strongly associated with risk for fatal than for nonfatal vascular events? PLoS Medicine, 6(6), e1000099. (doi: 10.1371/journal.pmed.1000099)

Schumacher, W., Cockcroft, J., Timpson, N., McEniery, C., Gallacher, J., Rumley, A., Lowe, G., Davey Smith, G., Wilkinson, I. and Ben Shlomo, Y. (2009) Association Between C-Reactive Protein Genotype, Circulating Levels, and Aortic Pulse Wave Velocity. Hypertension, 53(2), pp. 150-157. (doi: 10.1161/HYPERTENSIONAHA.108.117622)

Shah, T. et al. (2009) Critical appraisal of CRP measurement for the prediction of coronary heart disease events: new data and systematic review of 31 prospective cohorts. International Journal of Epidemiology, 38(1), pp. 217-231.

Wannamethee, S., Whincup, P., Shaper, A., Rumley, A., Lennon, L. and Lowe, G.D. (2009) Circulating inflammatory and hemostatic biomarkers are associated with risk of myocardial infarction and coronary death, but not angina pectoris, in older men. Journal of Thrombosis and Haemostasis, 7(10), pp. 1605-1611.

Welsh, P., Barber, M., Langhorne, P., Rumley, A., Lowe, G. and Stott, D. (2009) Associations of Inflammatory and Haemostatic Biomarkers with Poor Outcome in Acute Ischaemic Stroke. Cerebrovascular Diseases, 27(3), pp. 247-253. (doi: 10.1159/000196823)

Welsh, P., Woodward, M., Rumley, A. and Lowe, G.D. (2009) Associations of circulating TNF alpha and IL-18 with myocardial infarction and cardiovascular risk markers: The Glasgow Myocardial Infarction Study. Cytokine, 47(2), pp. 143-147.

Whiteley, W., Jackson, C., Lewis, S., Lowe, G.D., Rumley, A., Sandercock, P., Wardlaw, J., Dennis, M. and Sudlow, C. (2009) Inflammatory markers and poor outcome after stroke: a prospective cohort study and systematic review of interleukin-6. PLoS Medicine, 6(9), e1000145. (doi: 10.1371/journal.pmed.1000145)

Wild, S., Byrne, C., Tzoulaki, I., Lee, A., Rumley, A., Lowe, G. and Fowkes, F. (2009) Metabolic syndrome, haemostatic and inflammatory markers, cerebrovascular and peripheral arterial disease: The Edinburgh Artery Study. Atherosclerosis, 203(2), pp. 604-609.

Woodward, M., Tunstall-Pedoe, H., Rumley, A. and Lowe, G.D. (2009) Does fibrinogen add to prediction of cardiovascular disease? Results from the Scottish Heart Health Extended Cohort Study. British Journal of Haematology, 146(4), pp. 442-446.

2008

Brunner, E.J. et al. (2008) Inflammation, insulin resistance, and diabetes-mendelian randomization using CRP haplotypes points upstream. PLoS Medicine, 5(8), e155. (doi: 10.1371/journal.pmed.0050155)

Welsh, P. , Lowe, G.D., Chalmers, J., Campbell, D., Rumley, A., Neal, B.C., MacMahon, S.W. and Woodward, M. (2008) Associations of proinflammatory cytokines with the risk of recurrent stroke. Stroke, 39(8), pp. 2226-2230. (doi: 10.1161/STROKEAHA.107.504498)

Danesh, J. et al. (2008) Long-term interleukin-6 levels and subsequent risk of coronary heart disease: Two new prospective studies and a systematic review. PLoS Medicine, 5(4), e78. (doi: 10.1371/journal.pmed.0050078)

Bennet, A., Di Angelantonio, E., Erqou, S., Eiriksdottir, G., Sigurdsson, G., Woodward, M., Rumley, A., Lowe, G., Danesh, J. and Gudnason, V. (2008) Lipoprotein(a) levels and risk of future coronary heart disease. Archives of Internal Medicine, 168(6), pp. 598-608. (doi: 10.1001/archinte.168.6.598) (PMID:18362252)

Canonico, M., Plu-Bureau, G., Lowe, G. and Scarabin, P. (2008) Hormone replacement therapy and risk of venous thromboembolism in postmenopausal women: systematic review and meta-analysis. British Medical Journal, 336(7655), 1227-+. (doi: 10.1136/bmj.39555.441944.BE)

Crawley, J., Lane, D., Woodward, M., Rumley, A. and Lowe, G. (2008) Evidence that high von Willebrand factor and low ADAMTS-13 levels independently increase the risk of a non-fatal heart attack. Journal of Thrombosis and Haemostasis, 6(4), pp. 583-588. (doi: 10.1111/j.1538-7836.2008.02902.x)

Fraser, A., Fraser, A., Hughes, R., McCarthy, A., Tilling, K., Davies, D., Rumley, A., Lowe, G., Smith, G. and Ben Shlomo, Y. (2008) Early life growth and hemostatic factors. American Journal of Epidemiology, 168(2), pp. 179-187.

Freeman, D., Tham, K., Brown, E., Rumley, A., Lowe, G. and Greer, I. (2008) Placental corticotrophin-releasing hormone RNA and microparticles in maternal plasma are not measures of placental shedding of debris: reply to a rebuttal. Journal of Thrombosis and Haemostasis, 6(10), pp. 1838-1839.

Freeman, D., Tham, K., Brown, E., Rumley, A., Lowe, G. and Greer, I. (2008) Fetal corticotrophin-releasing hormone mRNA, but not phosphatidylserine-exposing microparticles, in maternal plasma are associated with factor VII activity in pre-eclampsia. Journal of Thrombosis and Haemostasis, 6(3), pp. 421-427. (doi: 10.1111/j.1538-7836.2007.02882.x)

Kelly, B., Wales, A., Wilson, A., Jackson, B., Leiberman, D.P. and Lowe, G.D. (2008) Getting research evidence into practice. Health Bulletin, 59, pp. 57-59.

Lawlor, D.A. et al. (2008) The association of C-reactive protein and CRP genotype with coronary heart disease: findings from five studies with 4,610 cases amongst 18,637 participants. PLoS ONE, 3(8), e3011. (doi: 10.1371/journal.pone.0003011) (PMID:18714384) (PMCID:PMC2507759)

Lowe, G. (2008) Coagulation factors, activation markers and risk of coronary heart disease: the Northwick Park Heart Studies. Journal of Thrombosis and Haemostasis, 6(2), pp. 256-258.

Lowe, G. (2008) Coagulation, genotypes and recurrent cardiovascular events: what further studies are required? Journal of Thrombosis and Haemostasis, 6(5), pp. 717-719. (doi: 10.1111/j.1538-7836.2008.02947.x)

Lowe, G. (2008) Thromboprophylaxis for patients at high risk of VTE. Lancet, 372(9643), pp. 1037-1038.

Lowe, G. and Ludlam, C. (2008) Less severe bleeding in hemophilia B than in hemophilia A. Journal of Thrombosis and Haemostasis, 6(11), pp. 1982-1983. (doi: 10.1111/j.1538-7836.2008.03126.x)

Poller, L. et al. (2008) A multicentre randomised clinical endpoint study of PARMA 5 computer-assisted oral anticoagulant dosage. British Journal of Haematology, 143(2), pp. 274-283.

Poller, L. et al. (2008) An international multicenter randomized study of computer-assisted oral anticoagulant dosage vs. medical staff dosage. Journal of Thrombosis and Haemostasis, 6(6), pp. 935-943.

Ramsay, S., Lowe, G., Whincup, P., Rumley, A., Morris, R. and Wannamethee, S. (2008) Relationships of inflammatory and haemostatic markers with social class: Results from a population-based study of older men. Atherosclerosis, 197(2), pp. 654-661.

Tabassum, F., Kumari, M., Rumley, A., Lowe, G., Power, C. and Strachan, D. (2008) Effects of socioeconomic position on inflammatory and hemostatic markers: A life-course analysis in the 1958 British birth cohort. American Journal of Epidemiology, 167(11), pp. 1332-1341.

Wannamethee, S., Sattar, N. , Rumley, A., Whincup, P., Lennon, L. and Lowe, G. (2008) Tissue plasminogen activator, von Willebrand factor, and risk of type 2 diabetes in older men. Diabetes Care, 31(5), pp. 995-1000.

Welsh, P.I. , Whincup, P.H., Papacosta, O., Wannamethee, S.G., Lennon, L., Thomson, A.H., Thomson, A.J., Rumley, A. and Lowe, G.D. (2008) Serum matrix metalloproteinase-9 and coronary heart disease: a prospective study in middle-aged men. QJM: An International Journal of Medicine, 101(10), pp. 785-791.

Welsh, P. , Woodward, M. and Lowe, G. (2008) Associations of plasma pro-inflammatory cytokines, fibrinogen, viscosity and C-reactive protein with cardiovascular risk factors and social deprivation: the fourth Glasgow MONICA study. British Journal of Haematology, 141(6), pp. 852-861.

Zhao, X., Courtney, J., Yin, H., West, R. and Lowe, G. (2008) Blood interactions with plasticised poly (vinyl chloride): influence of surface modification. Journal of Materials Science: Materials in Medicine, 19(2), pp. 713-719.

2007

Lara, J.J., Economou, M., Wallace, A.M., Rumley, A., Lowe, G., Slater, C., Caslake, M., Sattar, N. and Lean, M.E.J. (2007) Benefits of salmon eating on traditional and novel vascular risk factors in young, non-obese healthy subjects. Atherosclerosis, 193(1), pp. 213-221. (doi: 10.1016/j.atherosclerosis.2006.06.018)

Brown, K., Cherry, L., Lowe, G., Rumley, A., Sattar, N. , Tchernova, J., Wannamethee, S. and Whincup, P. (2007) Associations of adiponectin with metabolic and vascular risk parameters in the British Regional Heart Study reveal stronger links to insulin resistance-related than to coronory heart disease risk-related parameters. International Journal of Obesity, 31, pp. 1089-1098. (doi: 10.1038/sj.ijo.0803544)

Cherry, L., Lowe, G., Rumley, A., Sattar, N. , Wannamethee, S. and Whincup, P. (2007) Adipokines and risk of type 2 diabetes in older men. Diabetes Care, 30, pp. 1200-1205.

Deary, I., Fowkes, F., Lowe, G., Rafnsson, S., Rumley, A., Smith, F. and Whiteman, M. (2007) Cognitive decline and markers of inflammation and hemostasis: The Edinburgh Artery Study. Journal of the American Geriatrics Society, 55, pp. 700-707. (doi: 10.1111/j.1532-5415.2007.01158.x)

Fowkes, F., Lee, A., Lowe, G., Murray, G., Rumley, A. and Tzoulaki, I. (2007) Inflammatory, haemostatic, and rheological markers for incident peripheral arterial disease: Edinburgh Artery Study. European Heart Journal, 28, pp. 354-362. (doi: 10.1093/eurheartj/ehl441)

Fowkes, F., Lee, A., Lowe, G., Murray, G., Rumley, A. and Tzoulaki, I. (2007) Relative value of inflammatory, hemostatic, and rheological factors for incident myocardial infarction and stroke - The Edinburgh Artery Study. Circulation, 115, pp. 2119-2127. (doi: 10.1161/CIRCULATIONAHA.106.635029)

Gimeno, D., Brunner, E., Lowe, G., Rumley, A., Marmot, M. and Ferrie, J. (2007) Adult socioeconomic position, C-reactive protein and interleukin-6 in the Whitehall II prospective study. European Journal of Epidemiology, 22, pp. 675-683. (doi: 10.1007/s10654-007-9171-9)

Heikkila, K., Ebrahim, S., Rumley, A., Lowe, G. and Lawlor, D.A. (2007) Associations of circulating C-reactive protein and interleukin-6 with survival in women with and without cancer: Findings from the British Women's Heart and Health Study. Cancer Epidemiology, Biomarkers and Prevention, 16, pp. 1155-1159. (doi: 10.1158/9965.EPI-07-0093)

Humphries, S., Hurel, S., Lowe, G., Rumley, A. and Stephens, J. (2007) Association between plasma IL-6, the IL6-174G > C gene variant and the metabolic syndrome in type 2 diabetes mellitus. Molecular Genetics and Metabolism, 90(4), pp. 422-428.

Kaptoge, S., White, I., Thompson, S., Wood, A., Lewington, S., Lowe, G. and Danesh, J. (2007) Associations of plasma fibrinogen levels with established cardiovascular disease risk factors, inflammatory markers, and other characteristics: Individual participant meta-analysis of 154,211 adults in 31 prospective studies. American Journal of Epidemiology, 166, pp. 867-879. (doi: 10.1093/aje/kwm191)

Kelly, A., Lowe, G., Rumley, A., Sattar, N. , Tchernova, J., Wallace, A., Wannamethee, S. and Whincup, P. (2007) Plasma leptin: Associations with metabolic, inflammatory and haemostatic risk factors for cardiovascular disease. Atherosclerosis, 191, pp. 418-426. (doi: 10.1016/j.atherosclerosis.2006.04.012)

Lowe, G. (2007) Inflammatory/hemostatic biomarkers and cardiovascular risk: coming of age? Journal of Thrombosis and Haemostasis, 5(6), pp. 1125-1127.

Lowe, G. (2007) Is venous thrombosis a risk factor for arterial thrombosis? Lancet, 370(9601), pp. 1742-1744.

Lowe, G. (2007) Update on the cardiovascular risks of hormone replacement therapy. Women's Health, 3, pp. 87-97.

Lowe, G., Rudnicka, A., Rumley, A. and Strachan, D. (2007) Diurnal, seasonal, and blood-processing patterns in levels of circulating fibrinogen, fibrin D-dimer, C-reactive protein, tissue plasminogen activator, and von Willebrand factor in a 45-year-old population. Circulation, 115, pp. 996-1003. (doi: 10.1161/CIRCULATIONAHA.106.635169)

Lowe, G., Rumley, A., Wannamethee, S. and Whincup, P. (2007) Inter-relationships of interleukin-6, cardiovascular risk factors and the metabolic syndrome among older men. Journal of Thrombosis and Haemostasis, 5, pp. 1637-1643.

Power, C. et al. (2007) Life-course influences on health in British adults: effects of socio-economic position in childhood and adulthood. International Journal of Epidemiology, 36, pp. 532-539. (doi: 10.1093/ije/dy131O)

Sattar, N. , Crompton, P., Cherry, L., Kane, D., Lowe, G. and McInnes, I. (2007) Effects of tumor necrosis factor blockade on cardiovascular risk factors in psoriatic arthritis: a double-blind, placebo-controlled study. Arthritis and Rheumatism, 56, pp. 831-839. (doi: 10.1002/art.22447) (PMID:17328057)

Stephens, J., Hurel, S., Lowe, G., Rumley, A. and Humphries, S. (2007) Association between plasma IL-6, the IL6-174G > C gene variant and the metabolic syndrome in type 2 diabetes mellitus. Molecular Genetics and Metabolism, 90, pp. 422-428. (doi: 10.1016/j.ymgme.2006.10.004)

Woodward, M., Rumley, A., Welsh, P., Macmahon, S. and Lowe, G. (2007) A comparison of the associations between seven hemostatic or inflammatory variables and coronary heart disease. Journal of Thrombosis and Haemostasis, 5, pp. 1795-1800.

2006

Barber, M., Langhorne, P. , Rumley, A., Lowe, G.D.O. and Stott, D.J. (2006) D-dimer predicts early clinical progression in ischemic stroke: confirmation using routine clinical assays. Stroke, 37(4), pp. 1113-1115. (doi: 10.1161/01.STR.0000209240.63821.1a)

Anandan, C., Fowkes, F., Lee, A., Lowe, G., Powell, J., Rumley, A., Smith, F. and Tzoulaki, I. (2006) Reduced lung function in patients with abdominal aortic aneurysm is associated with activation of inflammation and hemostasis, not smoking or cardiovascular disease. Journal of Vascular Surgery, 43, pp. 474-480. (doi: 10.1016/j.jvs.2005.11.018)

Bruckdorfer, K., Lowe, G., Rumley, A., Wannamethee, S. and Whincup, P. (2006) Associations of vitamin C status, fruit and vegetable intakes, and markers of inflammation and hemostasis. American Journal of Clinical Nutrition, 83, pp. 567-574.

Collins, R., Danesh, J., Higgins, J., Keavney, B., Liu, E., Lowe, G. and Ye, Z. (2006) Seven haemostatic gene polymorphisms in coronary disease: meta-analysis of 66 155 cases and 91 307 controls. Lancet, 367, pp. 651-658.

Emberson, J., Lennon, L., Lowe, G., Rumley, A., Wannamethee, S. and Whincup, P. (2006) Effects of older age on fibrin D-dimer, C-reactive protein, and other hemostatic and inflammatory variables in men aged 60-79 years. Journal of Thrombosis and Haemostasis, 4, pp. 982-987.

Fowkes, F., Lee, A., Lowe, G., Murray, G., Price, J., Rumley, A., Smith, F. and Tzoulaki, I. (2006) Hemostatic factors, inflammatory markers, and progressive peripheral atherosclerosis - The Edinburgh Artery Study. American Journal of Epidemiology, 163, pp. 334-341. (doi: 10.1093/aje/kwj051)

Lennon, L., Lowe, G., Rumley, A., Shaper, A., Wannamethee, S. and Whincup, P. (2006) Renal function and cardiovascular mortality in elderly men: the role of inflammatory, procoagulant, and endothelial biomarkers. European Heart Journal, 27, pp. 2975-2981. (doi: 10.1093/eurheartj/ehl402)

Lowe, G. (2006) Arterial disease and venous thrombosis: are they related, and if so, what should we do about it? Journal of Thrombosis and Haemostasis, 4(9), pp. 1882-1885.

Lowe, G. (2006) The association between elevated levels of inflammation biomarkers and coronary artery disease and death. Canadian Medical Association Journal, 174(4), pp. 479-480.

Lowe, G. (2006) Can haematological tests predict cardiovascular risk? The 2005 Kettle Lecture. British Journal of Haematology, 133(3), pp. 232-250.

Lowe, G. (2006) Local inflammation, endothelial dysfunction and fibrinolysis in coronary heart disease. Clinical Science, 110(3), pp. 327-328.

Lowe, G. and Pepys, M. (2006) C-reactive protein and cardiovascular disease: Weighing the evidence. Current Atherosclerosis Reports, 8(5), pp. 421-428. (doi: 10.1007/s11883-006-0040-x)

Lowe, G. and Sattar, N. (2006) High sensitivity C-reactive protein and cardiovascular disease: an association built on unstable foundations? Annals of Clinical Biochemistry, 43, pp. 252-256.

Will, M., Bernacca, G., Bell, E., Tolland, M., Lowe, G., Rumley, A., Murray, H., Ford, I. and Wheatley, D. (2006) Our inability to predict thromboembolic events after prosthetic valve surgery. Journal of Heart Valve Disease, 15(4), pp. 570-580.

Woodward, M., Rumley, A., Rumley, A., Rumley, C., Lewington, S., Morrison, C. and Lowe, G. (2006) The association between homocysteine and myocardial infarction is independent of age, sex, blood pressure, cholesterol, smoking and markers of inflammation: the Glasgow Myocardial Infarction Study. Blood Coagulation and Fibrinolysis, 17, pp. 1-5.

Wu, O. et al. (2006) Screening for thrombophilia in high-risk situations: systematic review and cost-effectiveness analysis. The Thrombosis: Risk and Economic Assessment of Thrombophilia Screening (TREATS) study. Health Technology Assessment, 10, 1-+.

2005

Stott, D. J. et al. (2005) Randomized controlled trial of homocysteine-lowering vitamin treatment in elderly patients with vascular disease. American Journal of Clinical Nutrition, 82(6), pp. 1320-1326. (doi: 10.1093/ajcn/82.6.1320) (PMID:16332666)

Murdoch, D.L., O'Neill, K., Jackson, J., McMahon, A. , Rumley, A., Wallace, I., Lowe, G.D.O. and Tait, R.C. (2005) Are atrial fibrillation guidelines altering management? A community based study. Scottish Medical Journal, 50(4), pp. 166-169. (doi: 10.1177/003693300505000409) (PMID:16374981)

Danesh, J., Lewington, S., Thompson, S.G., Lowe, G.D.O. and Collins, R. (2005) Plasma fibrinogen level and the risk of major cardiovascular diseases and nonvascular mortality: an individual participant meta-analysis. JAMA: Journal of the American Medical Association, 294(14), pp. 1799-1809. (doi: 10.1001/jama.294.14.1799)

Barber, M., Lowe, G., Rumley, A., Scott, J., Stott, D. and Tait, R. (2005) Dementia in subjects with atrial fibrillation; haemostatic function and the role of anticoagulation (vol 33, pg 10, 2004). Age and Ageing, 34,

Belo, L., Santos-Silva, A., Lowe, G., Rumley, A., Quintanilha, A. and Rebelo, I. (2005) High-density lipoprotein particles may regulate hemostasis in human pregnancy. Fertility and Sterility, 84(4), pp. 1021-1022.

Cherry, L., Divecha, H., Lowe, G., Rumley, A., Sattar, N. and Sturrock, R. (2005) Cardiovascular risk parameters in men with ankylosing spondylitis in comparison with non-inflammatory control subjects: relevance of systemic inflammation. Clinical Science, 109(2), pp. 171-176.

Davey Smith, G., Lawlor, D.A., Harbord, R., Timpson, N., Rumley, A., Lowe, G.D.O., Day, I.N.M. and Ebrahim, S. (2005) Association of C-reactive protein with blood pressure and hypertension - Life course confounding and Mendelian randomization tests of causality. Arteriosclerosis, Thrombosis, and Vascular Biology, 25(5), pp. 1051-1056. (doi: 10.1161/01.ATV.0000160351.95181.d0)

Day, I.N.M., Ebrahim, S., Harbord, R., Lawlor, D.A., Lowe, G.D., Rumley, A., Smith, G.D. and Timpson, N. (2005) Association of C-reactive protein with blood pressure - Response. Arteriosclerosis, Thrombosis, and Vascular Biology, 25(9), E137-E138.

Fowkes, F., Lee, A., Lowe, G., Murray, G., Rumley, A. and Tzoulaki, I. (2005) C-reactive protein, interleukin-6, and soluble adhesion molecules as predictors of progressive peripheral atherosclerosis in the general population - Edinburgh Artery Study. Circulation, 112, pp. 976-983. (doi: 10.1161/CIRCULATIONHA.104.513085)

Kumari, M., Marmot, M., Rumley, A. and Lowe, G. (2005) Social, behavioral, and metabolic determinants of plasma viscosity in the Whitehall II Study. Annals of Epidemiology, 15, pp. 398-404. (doi: 10.1016/j.annepidem.2005.01.004)

Lawlor, D., Davey Smith, G., Rumley, A., Lowe, G. and Ebrahim, S. (2005) Associations of fibrinogen and C-reactive protein with prevalent and incident coronary heart disease are attenuated by adjustment for confounding factors - British Women's Heart and Health Study. Thrombosis and Haemostasis, 93(5), pp. 955-963. (doi: 10.1160/TH04-12-0805)

Lennon, L., Lowe, G., Rumley, A., Shaper, A., Wannamethee, S. and Whincup, P. (2005) Associations between cigarette smoking, pipe/cigar smoking, and smoking cessation, and haemostatic and inflammatory markers for cardiovascular disease. European Heart Journal, 26, pp. 1765-1773. (doi: 10.1093/eurheartj/ehi183)

Lennon, L., Lowe, G., Rumley, A., Shaper, A., Wannamethee, S. and Whincup, P. (2005) The metabolic syndrome and insulin resistance: relationship to haemostatic and inflammatory markers in older non-diabetic men. Atherosclerosis, 181, pp. 101-108. (doi: 10.1016/j.atherosclerosis.2004.12.031)

Lowe, G. (2005) Diagnosis and management of intermittent claudication. Prescriber, 2005, pp. 36-44.

Lowe, G.D.O. (2005) Circulating inflammatory markers and risks of cardiovascular and non-cardiovascular disease. Journal of Thrombosis and Haemostasis, 3(8), pp. 1618-1627. (doi: 10.1111/j.1538-7836.2005.01416.x)

Lowe, G.D.O. (2005) Fibrinogen measurement to assess the risk of arterial thrombosis in individual patients: not yet. Journal of Thrombosis and Haemostasis, 3(4), pp. 635-637. (doi: 10.1111/j.1538-7836.2005.01256.x)

Lowe, G.D.O. and Danesh, J. (2005) Classical and emerging risk factors for cardiovascular disease. Seminars in Vascular Medicine, 02(03), pp. 229-445.

Lowe, G.D.O., Rumley, A. and Wannamethee, S.G. (2005) Hemostatic abnormalities associated with obesity and the metabolic syndrome. Journal of Thrombosis and Haemostasis, 3(5), pp. 1076-1078. (doi: 10.1111/j.1538-7836.2005.01301.x)

Lowe, G. (2005) Fibrin D-Dimer and Cardiovascular Risk. [Article]. Seminars in Vascular Medicine Fibrin D-dimer Testing For Venous and Arterial Thrombotic Disease, Decemb(4), pp. 387-398.

Robins, J., Woodward, M., Lowe, G., McCaul, P., Cheyne, H. and Walker, J. (2005) First trimester maternal blood rheology and pregnancy induced hypertension. Journal of Obstetrics and Gynaecology, 25(8), pp. 746-750. (doi: 10.1080/01443610500314637)

Smith, A., Patterson, C., Yarnell, J., Rumley, A., Ben Shlomo, Y. and Lowe, G. (2005) Which hemostatic markers add to the predictive value of conventional risk factors for coronary heart disease and ischemic stroke? The Caerphilly Study. Circulation, 112, pp. 3080-3087. (doi: 10.1161/CIRCULATIONAHA.105.557132)

Timpson, N. et al. (2005) C-reactive protein and its role in metabolic syndrome: mendelian randomisation study. Lancet, 366(9501), pp. 1954-1959. (doi: 10.1016/S0140-6736(05)67786-0)

Woodward, M. et al. (2005) Associations of inflammatory and hemostatic variables with the risk of recurrent stroke. Stroke, 36(10), pp. 2143-2147. (doi: 10.1161/01.STR.0000181754.38408.4c)

Wu, O. et al. (2005) Oral contraceptives, hormone replacement therapy, thrombophilias and risk of venous thromboembolism: a systematic review. Thrombosis and Haemostasis, 94, pp. 17-25.

Wu, O. et al. (2005) Screening for thrombophilia in high-risk situations: a meta-analysis and cost-effectiveness analysis. British Journal of Haematology, 131, pp. 80-90. (doi: 10.1111/j.1365-2141.2005.05715.x)

Wu, O. , Clark, P., Lowe, G.D.O., Walker, I.D. and Greer, I.A. (2005) Thrombophilia and venous thromboembolism after total hip or knee replacement surgery: a systematic review. Journal of Thrombosis and Haemostasis, 3(4), pp. 811-813. (doi: 10.1111/j.1538-7836.2005.01264.x)

Wu, O. et al. (2005) Oral contraceptives, hormone replacement therapy, thrombophilias and risk of venous thromboembolism: a systematic review The Thrombosis: Risk and Economic Assessment of Thrombophilia Screening (TREATS) Study. Thrombosis and Haemostasis, 94(1), pp. 17-25. (doi: 10.1160/TH04-11-0759)

Yarnell, J., McCrum, E., Rumley, A., Patterson, C., Salomaa, V., Lowe, G. and Evans, A. (2005) Association of European population levels of thrombotic and inflammatory factors with risk of coronary heart disease: the MONICA Optional Haemostasis Study. European Heart Journal, 26, pp. 332-342. (doi: 10.1093/eurhreartj/ehi052)

2004

Barber, M., Tait, R.C. , Scott, J., Rumley, A., Lowe, G. and Stott, D.J. (2004) Dementia in subjects with atrial fibrillation: hemostatic function and the role of anticoagulation. Journal of Thrombosis and Haemostasis, 2(11), pp. 1873-1878. (doi: 10.1111/j.1538-7836.2004.00993.x) (PMID:15550013)

Lowe, G.D.O. (2004) Azithromycin does not reduce recurrent coronary events. Evidence-Based Healthcare, 8(2), pp. 105-106. (doi: 10.1016/j.ehbc.2004.02.019)

Lowe, G.D.O. (2004) Venous and arterial thrombosis: epidemiology and risk factors at various ages. Maturitas, 47(4), pp. 259-263. (doi: 10.1016/j.maturitas.2003.12.009)

Bainton, D., Ben, S.Y., Lowe, G.D.O., Rumley, A., Rumley, C., Sweetnam, P.M. and Yarnell, J.W.G. (2004) C-reactive protein, fibrin D-dimer, and risk of ischemic heart disease - The Caerphilly and Speedwell studies. Arteriosclerosis, Thrombosis, and Vascular Biology, 24, pp. 1957-1962. (doi: 10.1161/01.ATV.0000141842.27810.a9)

Barber, M., Langhorne, P. , Rumley, A., Lowe, G.D.O. and Stott, D.J. (2004) Hemostatic function and progressing ischemic stroke: D-dimer predicts early clinical progression. Stroke, 35(6), pp. 1421-1425. (doi: 10.1161/01.STR.0000126890.63512.41)

Campbell, S.E., Walker, A.E., Grimshaw, J.M., Campbell, M.K., Lowe, G.D.O., Harper, D., Fowkes, F.G.R. and Petrie, J.C. a. T. g. (2004) The prevalence of prophylaxis for deep vein thrombosis in acute hospital trusts. International Journal for Quality in Health Care, 13(4), pp. 309-316. (doi: 10.1093/intqhc/13.4.309)

Danesh, J., Wheeler, J.G., Hirschfield, G.M., Eda, S., Eiriksdottir, G., Rumley, A., Lowe, G.D.O., Pepys, M.B. and Gudnason, V. (2004) C-reactive protein and other circulating markers of inflammation in the prediction of coronary heart disease. New England Journal of Medicine, 350(14), pp. 1387-1397.

Emberson, J.R., Whincup, P.H., Morris, R.W., Walker, M., Lowe, G.D.O. and Rumley, A. (2004) Extent of regression dilution for established and novel coronary risk factors: Results from the British Regional Heart Study. European Journal of Cardiovascular Prevention and Rehabilitation, 11(2), pp. 125-134. (doi: 10.1097/01.hjr.0000114967.39211.e5)

Ford, I. , Lowe, G.D.O., McMahon, A.D. , O'Reilly, D.S., Packard, C.J. and Rumley, A. (2004) Interleukin-6, fibrin D-dimer, and coagulation factors VII and XIIa in prediction of coronary heart disease. Arteriosclerosis, Thrombosis, and Vascular Biology, 24, pp. 1529-1534. (doi: 10.1161/01.ATV.0000135995.39488.6c)

Fox, K., Gallimore, J., Gomma, A., Hirschfield, G., Lowe, G. and Pepys, M. (2004) Preprocedural inflammatory markers do not predict restenosis after successful coronary stenting. American Heart Journal, 147, pp. 1071-1077. (doi: 10.1016/j.ahj.2003.10.050)

Kostis, J.B. et al. (2004) Collaborative meta-analysis of prospective studies of plasma fibrinogen and cardiovascular disease. European Journal of Cardiovascular Prevention and Rehabilitation, 11(1), pp. 9-17.

Lowe, G., Danesh, J., Lewington, S., Walker, M., Lennon, L., Thomson, A., Rumley, A. and Whincup, P.H. (2004) Tissue plasminogen activator antigen and coronary heart disease. European Heart Journal, 25(3), pp. 252-259. (doi: 10.1016/j.ehj.2003.11.004)

Lowe, G.D.O. (2004) Dental disease, coronary heart disease and stroke, and inflammatory markers - What are the associations, and what do they mean? Circulation, 109(9), pp. 1076-1078. (doi: 10.1161/01.CIR.0000118643.41559.E2)

Lowe, G.D.O., Rumley, A. and Mackie, I.J. (2004) Plasma fibrinogen. Annals of Clinical Biochemistry, 41(6), pp. 430-440. (doi: 10.1258/0004563042466884)

Lowe, G.D.O., Rumley, A., Rumley, A.G., Rumley, J. and Woodward, M. (2004) Plasma lipid peroxides: relationships to cardiovascular risk factors and prevalent cardiovascular disease. QJM: An International Journal of Medicine, 97, pp. 809-816. (doi: 10.1093/qjmed/hch130)

Lowe, G. (2004) Hormone replacement therapy and cardiovascular disease: increased risks of venous thromboembolism and stroke, and no protection from coronary heart disease. Journal of Internal Medicine, 256, pp. 361-374.

Lowe, G., MacCallum, P., Meade, T., Rudnicka, A. and Rumley, A. (2004) Low-intensity warfarin reduces thrombin generation and fibrin turnover, but not low-grade inflammation, in men at risk of myocardial infarction. British Journal of Haematology, 127, pp. 448-450. (doi: 10.1111/j.1365-2141.2004.05222.x)

Lowe, G., Patterson, C., Sweetnam, P. and Yarnell, J. (2004) Haemostatic/inflammatory markers predict 10-year risk of IHD at least as well as lipids: the Caerphilly collaborative studies. European Heart Journal, 25, pp. 1049-1056. (doi: 10.1016/j.ehj.2004.04.011)

MacCallum, P.K., Cooper, J.A., Rumley, A., Lowe, G.D.O. and Meade, T.W. (2004) Effect of bezafibrate on plasma homocysteine concentration in men with lower extremity arterial disease. Journal of Thrombosis and Haemostasis, 2(2), pp. 364-365. (doi: 10.1111/j.1538-7933.2004.0584l.x)

Wannamethee, S.G., Lowe, G.D.O., Shaper, A.G., Rumley, A., Lennon, L. and Whincup, P.H. (2004) Insulin resistance, haemostatic and inflammatory markers and coronary heart disease risk factors in Type 2 diabetic men with and without coronary heart disease. Diabetologia, 47(9), pp. 1557-1565. (doi: 10.1007/s00125-004-1491-7)

Woodward, M., Lowe, G., Francis, L., Rumley, A. and Cobbe, S. (2004) A randomized comparison of the effects of aspirin and clopidogrel on thrombotic risk factors and C-reactive protein following myocardial infarction: the ADET trial. Journal of Thrombosis and Haemostasis, 2(11), pp. 1934-1940. (doi: 10.1111/j.1538-7836.2004.01017.x)

Yu, S.C., Lowe, G.D.O., Yarnell, J.W.G. and Sweetnam, P.M. (2004) Resonance-thrombography indices of the haemostatic process in relation to risk of incident coronary heart disease: 9 years follow-up in the Caerphilly Prospective Heart Disease Study. British Journal of Haematology, 126(3), pp. 385-391. (doi: 10.1111/j.1365-2141.2004.05054.x)

2003

Brull, D.J. et al. (2003) Human CRP gene polymorphism influences CRP levels - implications for the prediction and pathogenesis of coronary heart disease. Arteriosclerosis, Thrombosis, and Vascular Biology, 23(11), pp. 2063-2069. (doi: 10.1161/01.ATV.0000084640.21712.9C)

Forouhi, N.G., Rumley, A., Lowe, G.D., McKeigue, P. and Sattar, N. (2003) Specific elevation in plasma tissue plasminogen activator antigen concentrations in South Asians relative to Europeans. Blood Coagulation and Fibrinolysis, 14(8), pp. 755-760.

Imhof, A., Frohlich, M., Loewel, H., Helbecque, N., Woodward, M., Amouyel, P., Lowe, G.D.O. and Koenig, W. (2003) Distributions of C-reactive protein measured by high- sensitivity assays in apparently healthy men and women from different populations in Europe. Clinical Chemistry, 49(4), pp. 669-672. (doi: 10.1373/49.4.669)

Jespersen, J., Lowe, G., Samsioe, G., Skouby, S. and Stevenson, J. (2003) The European Consensus Development Conference 2002: Sex Steroids and Cardiovascular Diseases - On the route to combined evidence from OC and HRT/ERT. Maturitas, 44, pp. 69-82. (doi: 10.1016/S0378-5122(02)00351-1)

Lowe, G.D.O., Sandercock, P.A.G. and Rosendaal, F.R. (2003) Prevention of venous thromboembolism after major orthopaedic surgery: is fondaparinux an advance? Lancet, 362(9383), pp. 504-505. (doi: 10.1016/S0140-6736(03)14149-9)

Lowe, G.D.O., Woodward, M., Rumley, A., Morrison, C. and Nieuwenhuizen, W. (2003) Associations of plasma fibrinogen assays, C-reactive protein and interleukin-6 with previous myocardial infarction. Journal of Thrombosis and Haemostasis, 1(11), pp. 2312-2316. (doi: 10.1046/j.1538-7836.2003.00467.x)

Lowe, G./, Woodward, M., Rumley, A./, Morrison, C., Tunstall-Pedoe, H. and Stephen, K. (2003) Total tooth loss and prevalent cardiovascular disease in men and women - Possible roles of citrus fruit consumption, vitamin C, and inflammatory and thrombotic variables. Journal of Clinical Epidemiology, 56(7), pp. 694-700. (doi: 10.1016/S0895-4356(03)00086-6)

Lowe, G. (2003) Clopidogrel in prevention of cardiovascular events. Reviews in Contemporary Pharmacology, 12, pp. 265-298.

Lowe, G., Rosendaal, F. and Sandercock, P. (2003) Fondaparinux and prevention of venous thromboembolism after orthopaedic surgery - Reply. Lancet, 362(9395), p. 1582.

Lowe, G. (2003) Different locations of atherosclerosis - Different risk factors, different therapies? Pathophysiology of Haemostasis and Thrombosis, 33, pp. 262-266.

Lowe, G. (2003) Virchow's triad revisited: Abnormal flow. Pathophysiology of Haemostasis and Thrombosis, 33, pp. 455-457.

Mackie, I.J., Kitchen, S., Machin, S.J. and Lowe, G.D.O. (2003) Guidelines on fibrinogen assays. British Journal of Haematology, 121(3), pp. 396-404. (doi: 10.1046/j.1365-2141.2003.04256.x)

Maclean, P.S., Tait, R.C. , Lowe, G.D.O., Walker, I.D. and McColl, M.D. (2003) Successful elimination of factor VIII inhibitor using cyclosporin A. British Journal of Haematology, 122(6), pp. 1024-1025. (doi: 10.1046/j.1365-2141.2003.04519.x)

Maclean, P.S., Tait, R.C., Rumley, A., McMahon, A. and Lowe, G.D. (2003) Anticoagulation with warfarin downregulates inflammation. Journal of Thrombosis and Haemostasis, 1(8), pp. 1838-1839. (doi: 10.1046/j.1538-7836.2003.t01-1-00372.x)

McKenzie, J. et al. (2003) Metabolic, inflammatory and haemostatic effects of a low-dose continuous combined HRT in women with type 2 diabetes: potentially safer with respect to vascular risk? Clinical Endocrinology, 59(6), pp. 682-689. (doi: 10.1046/j.1365-2265.2003.01906.x)

Paisley, K.E., Beaman, M., Tooke, J.E., Mohamed-Ali, V., Lowe, G.D.O. and Shore, A.C. (2003) Endothelial dysfunction and inflammation in asymptomatic proteinuria. Kidney International, 63(2), pp. 624-633. (doi: 10.1046/j.1523-1755.2003.00768.x)

Perry, C.G., Spiers, A., Cleland, S.J., Lowe, G.D.O., Petrie, J.R. and Connell, J.M.C. (2003) Glucocorticoids and insulin sensitivity: dissociation of insulin's metabolic and vascular actions. Journal of Clinical Endocrinology and Metabolism, 88(12), pp. 6008-6014. (doi: 10.1210/jc.2002-021605)

Rumley, A., Woodward, M., Hoffmeister, A., Koenig, W. and Lowe, G.D.O. (2003) Comparison of plasma fibrinogen by Clauss, prothrombin time- derived, and immunonephelometric assays in a general population: implications for risk stratification by thirds of fibrinogen. Blood Coagulation and Fibrinolysis, 14(2), pp. 197-201.

Smith, F., Connor, J.M., Lee, A.J., Cooke, A., Lowe, G.D.O., Rumley, A. and Fowkes, F.G. (2003) Relationship of the platelet glycoprotein P1(A) and fibrinogen T/G(+1689) polymorphisms with peripheral arterial disease and ischaemic heart disease. Thrombosis Research, 112(4), pp. 209-216. (doi: 10.1016/j.thromres.2003.11.010)

Stansby, G. et al. (2003) Antiplatelet therapy in peripheral arterial disease. Consensus statement. European Journal of Vascular and Endovascular Surgery, 26(1), pp. 1-16. (doi: 10.1053/ejvs.2002.1927)

Steptoe, A., Kunz-Ebrecht, S., Owen, N., Feldman, P.J., Rumley, A., Lowe, G.D.O. and Marmot, M. (2003) Influence of socioeconomic status and job control on plasma fibrinogen response's to acute mental stress. Psychosomatic Medicine, 65(1), pp. 137-144. (doi: 10.1097/01.PSY.0000039755.23250.A7)

Steptoe, A., Kunz-Ebrecht, S., Rumley, A. and Lowe, G.D.O. (2003) Prolonged elevations in haemostatic and rheological responses following psychological stress in low socioeconomic status men and women. Thrombosis and Haemostasis, 89(1), pp. 83-90.

Wannamethee, S.G., Lowe, G.D.O., Shaper, G., Whincup, P.H., Rumley, A., Walker, M. and Lennon, L. (2003) The effects of different alcoholic drinks on lipids, insulin and haemostatic and inflammatory markers in older men. Thrombosis and Haemostasis, 90(6), pp. 1080-1087.

Woodward, M., Lowe, G., Rumley, A., Imhof, A. and Koenig, W. (2003) Measurement of plasma viscosity in stored frozen samples: a general population study. Blood Coagulation and Fibrinolysis, 14(4), pp. 417-420.

Woodward, M., Oliphant, J., Lowe, G. and Tunstall-Pedoe, H. (2003) Contribution of contemporaneous risk factors to social inequality in coronary heart disease and all causes mortality. Preventive Medicine, 36(5), pp. 561-568. (doi: 10.1016/S0091-7435(03)00010-0)

Woodward, M., Rumley, A., Lowe, G.D.O. and Tunstall-Pedoe, H. (2003) C-reactive protein: associations with haematological variables, cardiovascular risk factors and prevalent cardiovascular disease. British Journal of Haematology, 122(1), pp. 135-141. (doi: 10.1046/j.1365-2141.2003.04387.x)

Woodward, M., Rumley, A., Tunstall-Pedoe, H. and Lowe, G.D.O. (2003) Does sticky blood predict a sticky end? Associations of blood viscosity, haematocrit and fibrinogen with mortality in the West of Scotland. British Journal of Haematology, 122(4), pp. 645-650. (doi: 10.1046/j.1365-2141.2003.04475.x)

2002

Dykes, A.C., Walker, I.D., Lowe, G.D.O. and Tait, R.C. (2002) Treatment of acquired haemophilia. Internal Medicine Journal, 32(12), 625-6U4. (doi: 10.1046/j.1445-5994.2002.00303.x) (PMID:12512761)

Wannamethee, S.G., Lowe, G.D.O., Whincup, P.H., Rumley, A., Walker, M. and Lennon, L. (2002) Physical activity and hemostatic and inflammatory variables in elderly men. Circulation, 105(15), pp. 1785-1790.

Basso, F., Lowe, G.D.O., Rumley, A., McMahon, A.D. and Humphries, S.E. (2002) Interleukin-6 -174G > C polymorphism and risk of coronary heart disease in West of Scotland Coronary Prevention Study (WOSCOPS). Arteriosclerosis, Thrombosis, and Vascular Biology, 22(4), pp. 599-604. (doi: 10.1161/01.ATV.0000013283.84306.1A)

Belo, L., Santos-Silva, A., Rumley, A., Lowe, G., Pereira-Leite, L., Quintanilha, A. and Rebelo, I. (2002) Elevated tissue plasminogen activator as a potential marker of endothelial dysfunction in pre-eclampsia: correlation with proteinuria. BJOG: An International Journal of Obstetrics and Gynaecology, 109(11), pp. 1250-1255. (doi: 10.1016/S1470-0328(02)01957-2)

Bergqvist, D. and Lowe, G. (2002) Venous thromboembolism in patients undergoing laparoscopic and arthroscopic surgery and in leg casts. Archives of Internal Medicine, 162(19), pp. 2173-2176.

Brull, D.J., Dhamrait, S., Moulding, R., Rumley, A., Lowe, G.D.O., World, M.J., Humphries, S.E. and Montgomery, H.E. (2002) The effect of fibrinogen genotype on fibrinogen levels after strenuous physical exercise. Thrombosis and Haemostasis, 87(1), pp. 37-41.

Brull, D.J., Sanders, J., Rumley, A., Lowe, G.D., Humphries, S.E. and Montgomery, H.E. (2002) Impact of angiotensin converting enzyme inhibition on post- coronary artery bypass interleukin 6 release. Heart, 87(3), pp. 252-255.

Brunner, E. et al. (2002) Adrenocortical, autonomic, and inflammatory causes of the metabolic syndrome - nested case-control study. Circulation, 106(21), pp. 2659-2665. (doi: 10.1161/01.CIR.0000038364.26310.BD)

Freeman, D.J. , Norrie, J., Caslake, M.J., Gaw, A., Ford, I. , Lowe, G.D.O., O'Reilly, D. S. J.,, Packard, C.J. and Sattar, N. (2002) C-reactive protein is an independent predictor of risk for the development of diabetes in the West of Scotland Coronary Prevention Study. Diabetes, 51(5), pp. 1596-1600. (doi: 10.2337/diabetes.51.5.1596)

Freeman, D.J. , Norrie, J., Caslake, M.J., Gaw, A., Ford, I. , Lowe, G.D.O., O'Reilly, D.S., Packard, C.J. and Sattar, N. (2002) C-reactive protein is an independent predictor of risk for the development of diabetes in the West of Scotland Coronary Prevention Study. Diabetes, 51(5), pp. 1596-1600.

Hankey, C.R., Lean, M.E.J. , Lowe, G.D.O., Rumley, A. and Woodward, M. (2002) Effects of moderate weight loss on anginal symptoms and indices of coagulation and fibrinolysis in overweight patients with angina pectoris. European Journal of Clinical Nutrition, 56(10), pp. 1039-1045.

Kelly, C.J.G., Lyall, H., Petrie, J.R. , Gould, G.W. , Connell, J.M.C., Rumley, A., Lowe, G.D.O. and Sattar, N. (2002) A specific elevation in tissue plasminogen activator antigen in women with polycystic ovarian syndrome. Journal of Clinical Endocrinology and Metabolism, 87(7), pp. 3287-3290. (doi: 10.1210/jc.87.7.3287)

Lowe, G.D.O. (2002) Hormone replacement therapy: prothrombotic vs. protective effects. Pathophysiology of Haemostasis and Thrombosis, 32(5-6), pp. 329-332. (doi: 10.1159/000073592)

Lowe, G.D.O. (2002) Measurement of thrombosis and its prevention. British Journal of Clinical Pharmacology, 54(1), pp. 96-100. (doi: 10.1046/j.1365-2125.2002.01626.x)

Lowe, G.D.O. (2002) Which patients with diabetes should receive which antiplatelet agents? British Journal of Diabetes and Vascular Disease, 2002(2), pp. 157-160. (doi: 10.1177/14746514020020030201)

Lowe, G.D.O., Rumley, A., Whincup, P.H. and Danesh, J. (2002) Hemostatic and rheological variables and risk of cardiovascular disease. Seminars in Vascular Medicine, 2002(2), pp. 429-440. (doi: 10.1055/s-2002-36771)

Lowe, G. and Danesh, J. (2002) Classical and Emerging Risk Factors for Cardiovascular Disease. [Miscellaneous]. Seminars in Vascular Medicine, 2(3), p. 229.

Lowe, G., Rumley, A., Whincup, P. and Danesh, J. (2002) Hemostatic and Rheological Variables and Risk of Cardiovascular Disease. [Article]. Seminars in Vascular Medicine Classical and Emerging Risk Factors For Cardiovascular Disease, Part 2, 2002;2(4), pp. 429-440.

Mackie, I.J., Lawrie, A.S., Kitchen, S., Gaffney, P.J., Howarth, D., Lowe, G.D.O., Martin, J., Purdy, G., Rigsby, P. and Rumley, A. (2002) A performance evaluation of commercial fibrinogen reference preparations and assays for Clauss and PT-derived fibrinogen. Thrombosis and Haemostasis, 87(6), pp. 997-1005.

Rosendaal, F.R., Vessey, M., Rumley, A., Daly, E., Woodward, M., Helmerhorst, F.M. and Lowe, G.D. (2002) Hormonal replacement therapy, prothrombotic mutations and the risk of venous thrombosis. British Journal of Haematology, 116(4), pp. 851-854. (doi: 10.1046/j.0007-1048.2002.03356.x)

Whincup, R.H., Danesh, J., Walker, M., Lennon, L., Thomson, A., Appleby, R., Rumley, A. and Lowe, G.D.O. (2002) von Willebrand factor and coronary heart disease - prospective study and meta-analysis. European Heart Journal, 23(22), pp. 1764-1770. (doi: 10.1053/euhj.2001.3237)

Zito, F., Lowe, G.D.O., Rumley, A., McMahon, A.D. and Humphries, S.E. (2002) Association of the factor XII 46C > T polymorphism with risk of coronary heart disease (CHD) in the WOSCOPS study. Atherosclerosis, 165(1), pp. 153-158. (doi: 10.1016/S0021-9150(02)00196-X)

2001

Lowe, G.D.O., Upton, M.N., Rumley, A., McConnachie, A. , O'Reilly, D.S. and Watt, G.C.M. (2001) Different effects of oral and transdermal hormone replacement therapies on Factor IX, APC resistance, t-PA, PAI and C- reactive protein - a cross-sectional population survey. Thrombosis and Haemostasis, 86(2), pp. 550-556.

Brull, D.J., Montgomery, H.E., Sanders, J., Dhamrait, S., Luong, L., Rumley, A., Lowe, G.D.O. and Humphries, S.E. (2001) Interleukin-6 gene -174G gt C and -572G gt C promoter polymorphisms are strong predictors of plasma - Interleukin-6 levels after coronary artery bypass surgery. Arteriosclerosis, Thrombosis, and Vascular Biology, 21(9), pp. 1458-1463.

Brull, D.J., Sanders, J., Rumley, A., Lowe, G.D.O., Humphries, S.E. and Montgomery, H.E. (2001) Statin therapy and the acute inflammatory response after coronary artery bypass grafting. American Journal of Cardiology, 88(4), pp. 431-433. (doi: 10.1016/S0002-9149(01)01696-4)

Danesh, J., Whincup, P., Walker, M., Lennon, L., Thomson, A., Appleby, P., Rumley, A. and Lowe, G.D.O. (2001) Fibrin D-dimer and coronary heart disease - prospective study and meta-analysis. Circulation, 103(19), pp. 2323-2327.

Davie, A.P., Rumley, A., Lowe, G.D.O. and McMurray, J.J.V. (2001) Effect of chronic angiotensin II type I receptor antagonism and angiotensin converting enzyme inhibition on plasma fibrinolytic variables in patients with heart failure. Thrombosis and Haemostasis, 86(6), pp. 1585-1586. (PMID:11776334)

Dykes, A.C., Walker, I.D., Lowe, G.D.O. and Tait, R.C. (2001) Combined prednisolone and intravenous immunoglobulin treatment for acquired factor VIII inhibitors: a 2-year review. Haemophilia, 7(2), pp. 160-163. (doi: 10.1046/j.1365-2516.2001.00489.x)

Lee, B.C., Shore, A.C., Humphreys, J.M., Lowe, G.D., Rumley, A., Clark, P.M., Hattersley, A.T. and Tooke, J.E. (2001) Skin microvascular vasodilatory capacity in offspring of two parents with Type 2 diabetes. Diabetic Medicine, 18(7), pp. 541-545. (doi: 10.1046/j.1464-5491.2001.00514.x)

Lowe, G.D.O. (2001) Factor IX and thrombosis. British Journal of Haematology, 115(3), pp. 507-513. (doi: 10.1046/j.1365-2141.2001.03186.x)

Lowe, G.D.O. (2001) Is sticky blood a treatable determinant of cognitive decline and of dementia? Age and Ageing, 30(2), pp. 101-103.

Lowe, G.D.O. (2001) Who should take aspirin for primary prophylaxis of coronary heart disease? Heart, 85(3), pp. 245-246. (doi: 10.1136/heart.85.3.245)

Lowe, G.D.O. (2001) Why do smokers have higher plasma fibrinogen levels than non- smokers? Clinical Science, 101(2), pp. 209-210.

Lowe, G.D.O. and Rumley, A. (2001) Fibrinogen and its degradation products as thrombotic risk factors. Annals of the New York Academy of Sciences, 936, pp. 560-565.

Lowe, G.D.O., Rumley, A., Sweetnam, P.M., Yarnell, J.W.G. and Rumley, J. (2001) Fibrin D-dimer, markers of coagulation activation and the risk of major ischaemic heart disease in the Caerphilly Study. Thrombosis and Haemostasis, 86(3), pp. 822-827.

Lowe, G.D.O., Yarnell, J.W.G., Rumley, A., Bainton, D. and Sweetnam, P.M. (2001) C-Reactive protein, fibrin D-dimer, and incident ischemic heart disease in the speedwell study - Are inflammation and fibrin turnover linked in pathogenesis? Arteriosclerosis, Thrombosis, and Vascular Biology, 21(4), pp. 603-610.

Lowe, G. (2001) Ancrod in treatment of acute ischaemic stroke. Proceedings of the Royal College of Physicians of Edinburgh, 31(Suppl.), pp. 20-24.

Lowe, G. (2001) Scottish physicians' clinical standards and audit colaboration. Proceedings of the Royal College of Physicians of Edinburgh, 31, p. 252.

Lowe, G. (2001) Why do smokers have higher plasma fibrinogen levels than non-smokers? Clinical Science, 101(2), pp. 209-210.

Mamode, N., Docherty, G., Lowe, G.D.O., Macfarlane, P.W., Martin, W., Pollock, J.G. and Cobbe, S.M. (2001) The role of myocardial perfusion scanning, heart rate variability and D-dimers in predicting the risk of perioperative cardiac complications after peripheral vascular surgery. European Journal of Vascular and Endovascular Surgery, 22(6), pp. 499-508. (doi: 10.1053/ejvs.2001.1529)

McEntegart, A., Capell, H.A., Creran, D., Rumley, A., Woodward, M. and Lowe, G.D.O. (2001) Cardiovascular risk factors, including thrombotic variables, in a population with rheumatoid arthritis. Rheumatology, 40(6), pp. 640-644. (doi: 10.1093/rheumatology/40.6.640)

Perera, M., Sattar, N. , Petrie, J.R. , Hillier, C., Small, M., Connell, J.M.C., Lowe, G.D.O. and Lumsden, M.A. (2001) The effects of transdermal estradiol in combination with oral norethisterone on lipoproteins, coagulation, and endothelial markers in postmenopausal women with type 2 diabetes: a randomized, placebo-controlled study. Journal of Clinical Endocrinology and Metabolism, 86(3), pp. 1140-1143. (doi: 10.1210/jc.86.3.1140)

Price, J.F., Lee, A.J., Rumley, A., Lowe, G.D.O. and Fowkes, F.G.R. (2001) Lipoprotein (a) and development of intermittent claudication and major cardiovascular events in men and women: the Edinburgh Artery Study. Atherosclerosis, 157(1), pp. 241-249. (doi: 10.1016/S0021-9150(00)00719-X)

Stonier, P. and Lowe, G. (2001) A national panel for research integrity: a proposed blueprint for the prevention and investigation of misconduct in biomedical research. Proceedings of the Royal College of Physicians of Edinburgh, 31, pp. 253-255.

Stott, D.J. , Spilg, E., Campbell, A.M., Rumley, A., Mansoor, M.A. and Lowe, G.D.O. (2001) Haemostasis in ischaemic stroke and vascular dementia. Blood Coagulation and Fibrinolysis, 12(8), pp. 651-657.

Yarnell, J.W.G., Sweetnam, P.M., Rumley, A. and Lowe, G.D.O. (2001) Lifestyle factors and coagulation activation markers: the Caerphilly Study. Blood Coagulation and Fibrinolysis, 12(8), pp. 721-728.

2000

Danesh, J., Collins, R., Peto, R. and Lowe, G.D.O. (2000) Haematocrit, viscosity, erythrocyte sedimentation rate: meta- analyses of prospective studies of coronary heart disease. European Heart Journal, 21(7), pp. 515-520. (doi: 10.1053/euhj.1999.1699)

Fowkes, F.G.R., Lee, A.J., Hau, C.M., Cooke, A., Connor, J.M. and Lowe, G.D.O. (2000) Methylene tetrahydrofolate reductase (MTHFR) and nitric oxide synthase (ecNOS) genes and risks of peripheral arterial disease and coronary heart disease: Edinburgh artery study. Atherosclerosis, 150(1), pp. 179-185. (doi: 10.1016/S0021-9150(99)00366-4)

Hutchinson, W.L., Koenig, W., Frohlich, M., Sund, M., Lowe, G.D.O. and Pepys, M.B. (2000) Immunoradiometric assay of circulating C-reactive protein: age-related values in the adult general population. Clinical Chemistry, 46(7), pp. 934-938.

Kinane, D.F. and Lowe, G.D.O. (2000) How periodontal disease may contribute to cardiovascular disease. Periodontology 2000, 23, pp. 121-126. (doi: 10.1034/j.1600-0757.2000.2230112.x)

Lamba, N.M.K., Courtney, J.M., Gaylor, J.D.S. and Lowe, G.D.O. (2000) In vitro investigation of the blood response to medical grade PVC and the effect of heparin on the blood response. Biomaterials, 21(1), pp. 89-96. (doi: 10.1016/S0142-9612(99)00145-3)

Lee, A.J., Lowe, G.D.O., Rumley, A., Ruckley, C.V. and Fowkes, F.G.R. (2000) Haemostatic factors and risk of varicose veins and chronic venous insufficiency: Edinburgh vein study. Blood Coagulation and Fibrinolysis, 11(8), pp. 775-781.

Leng, G.C. et al. (2000) Femoral atherosclerosis in an older British population: prevalence and risk factors. Atherosclerosis, 152(1), pp. 167-174. (doi: 10.1016/S0021-9150(99)00447-5)

Lowe, G., Rumley, A., Norrie, J., Ford, I. , Shepherd, J., Cobbe, S., Macfarlane, P. and Packard, C. (2000) Blood rheology, cardiovascular risk factors, and cardiovascular disease: The West of Scotland Coronary Prevention Study. Thrombosis and Haemostasis, 84(4), pp. 553-558.

Lowe, G., Rumley, A., Woodward, M. and Vessey, M. (2000) C-reactive protein, idiopathic venous thromboembolism and hormone replacement therapy. Thrombosis and Haemostasis, 84(4), pp. 730-731.

Lowe, G., Woodward, M., Vessey, M., Rumley, A., Gough, P. and Daly, E. (2000) Thrombotic variables and risk of idiopathic venous thromboembolism in women aged 45-64 years - Relationships to hormone replacement therapy. Thrombosis and Haemostasis, 83(4), pp. 530-535.

Ludlam, C.A., Lee, R.J., Prescott, R.J., Andrews, J., Kirke, E., Thomas, A.E., Chalmers, E. and Lowe, G.D.O. (2000) Haemophilia care in central Scotland 1980-94. I. Demographic characteristics, hospital admissions and causes of death. Haemophilia, 6(5), pp. 494-503. (doi: 10.1046/j.1365-2516.2000.00405.x)

Packard, C.J. et al. (2000) Lipoprotein-associated phospholipase A(2) as an independent predictor of coronary heart disease. New England Journal of Medicine, 343(16), pp. 1148-1155.

Smith, F., Lee, A.J., Hau, C.M., Rumley, A., Lowe, G.D.O. and Fowkes, F.G.R. (2000) Plasma fibrinogen, haemostatic factors and prediction of peripheral arterial disease in the Edinburgh Artery Study. Blood Coagulation and Fibrinolysis, 11(1), pp. 43-50.

Smith, F.B., Fowkes, F.G.R., Rumley, A.,, Lee, A.J., Lowe, G.D.O. and Hau, C.M. (2000) Tissue plasminogen activator and leucocyte elastase as predictors of cardiovascular events in subjects with angina pectoris: Edinburgh Artery Study. European Heart Journal, 21(19), pp. 1607-1613. (doi: 10.1053/euhj.2000.2127)

Yarnell, J.W.G., Sweetnam, P.M., Rumley, A. and Lowe, G.D.O. (2000) Lifestyle and hemostatic risk factors for ischemic heart disease - The Caerphilly Study. Arteriosclerosis, Thrombosis, and Vascular Biology, 20(1), pp. 271-279.

1997

Gilhooly, C. , Mansfield, M.D., Rumley, A., Lowe, G. and Kinsella, J. (1997) Investigation of haemostatic parameters in relation to outcome in an intensive care population. European Journal of Anaesthesiology, 14(5), p. 524.

1992

Collier, A., Rumley, A., Rumley, A. G., Patesron, J. R., Leach, J. P. , Lowe, G. D.O. and Small, M. (1992) Free radical activity and hemostatic factors in NIDDM patients with and without microalbuminuria. Diabetes, 41(8), pp. 909-913. (doi: 10.2337/diab.41.8.909) (PMID:1628764)

Articles

Lowe, G., Wu, O. , van Hylckama Vlieg, A., Folsom, A., Rosendaal, F. and Woodward, M. (2023) Plasma levels of coagulation factors VIII and IX and risk of venous thromboembolism: systematic review and meta-analysis. Thrombosis Research, 229, pp. 31-39. (doi: 10.1016/j.thromres.2023.06.026)

Lowe, G., Peters, S. A.E., Rumley, A., Tunstall-Pedoe, H. and Woodward, M. (2022) Associations of haemostatic variables with cardiovascular disease and total mortality - the Glasgow MONICA Study. TH Open, 6(2), e107-e113. (doi: 10.1055/a-1789-4896)

Wannamethee, S. G., Papacosta, O., Lennon, L., Whincup, P. H., Rumley, A. and Lowe, G. D.O. (2022) Haematological variables and risk of future venous thromboembolism in the British Regional Heart Study on men. Combined D‐dimer and APTT as a predictive test for thromboembolism? British Journal of Haematology, (doi: 10.1111/bjh.18288) (PMID:35655415)

Lowe, G. (2022) Thrombosis in Scotland, 1800–1960. Journal of the Royal College of Physicians of Edinburgh, 52(2), pp. 153-158. (doi: 10.1177/14782715221107949)

Lowe, G. (2021) The birth of British geriatric medicine: further information on Scotland. Journal of the Royal College of Physicians of Edinburgh, 51(4), pp. 424-427. (doi: 10.4997/JRCPE.2021.427) (PMID:34882152)

Kitas, G. D. et al. (2019) A multicenter, randomized, placebo‐controlled trial of atorvastatin for the primary prevention of cardiovascular events in patients with rheumatoid arthritis. Arthritis and Rheumatology, 71(9), pp. 1437-1449. (doi: 10.1002/art.40892) (PMID:30983166) (PMCID:PMC6771601)

Gregson, J. et al. (2019) Cardiovascular risk factors associated with venous thromboembolism. JAMA Cardiology, 4(2), pp. 163-173. (doi: 10.1001/jamacardio.2018.4537) (PMID:30649175) (PMCID:PMC6386140)

Patterson, C. C., Blankenberg, S., Ben-Shlomo, Y., Heslop, L., Bayer, A., Lowe, G., Zeller, T., Gallacher, J., Young, I. and Yarnell, J. W.G. (2018) Troponin and BNP are markers for subsequent non-ischaemic congestive heart failure: the Caerphilly Prospective Study (CaPS). Open Heart, 5(1), e000692. (doi: 10.1136/openhrt-2017-000692) (PMID:29531757) (PMCID:PMC5845403)

Spronk, H. et al. (2018) Atherothrombosis and thromboembolism: position paper from the Second Maastricht consensus Conference on thrombosis. Thrombosis and Haemostasis, 118(2), pp. 229-250. (doi: 10.1160/th17-07-0492) (PMID:29378352)

Lowe, G. D.O. (2018) Self-related health and blood hypercoagulability: a possible mechanism for cardiovascular risk. Thrombosis and Haemostasis, 118(1), pp. 4-5. (doi: 10.1160/th17-11-0836) (PMID:29304521)

Sartini, C., Whincup, P. H., Wannamethee, S. G., Jefferis, B. J., Lennon, L., Lowe, G. D.O., Welsh, P. , Sattar, N. and Morris, R. W. (2017) Associations of time of day with cardiovascular disease risk factors measured in older men: results from the British Regional Heart Study. BMJ Open, 7(11), e018264. (doi: 10.1136/bmjopen-2017-018264) (PMID:29133328) (PMCID:PMC5695475)

Wannamethee, S. G., Whincup, P. H., Papacosta, O., Lennon, L. and Lowe, G. D. (2017) Associations between blood coagulation markers, NT-proBNP and risk of incident heart failure in older men: The British Regional Heart Study. International Journal of Cardiology, 230, pp. 567-571. (doi: 10.1016/j.ijcard.2016.12.056) (PMID:28043678) (PMCID:PMC5267630)

Sartini, C. et al. (2017) Relationship between outdoor temperature and cardiovascular disease risk factors in older people. European Journal of Preventive Cardiology, 24(4), pp. 349-356. (doi: 10.1177/2047487316682119) (PMID:27899528)

de Vries, P. S. et al. (2017) Comparison of HapMap and 1000 genomes reference panels in a large-scale genome-wide association study. PLoS ONE, 12(1), e0167742. (doi: 10.1371/journal.pone.0167742) (PMID:28107422) (PMCID:PMC5249120)

Peters, S. A.E., Woodward, M., Rumley, A., Tunstall-Pedoe, H. D. and Lowe, G. D.O. (2017) Plasma and blood viscosity in the prediction of cardiovascular disease and mortality in the Scottish Heart Health Extended Cohort Study. European Journal of Preventive Cardiology, 24(2), pp. 161-167. (doi: 10.1177/2047487316672004) (PMID:27798361)

Lazzarino, A. I., Hamer, M., Gaze, D., Collinson, P., Rumley, A., Lowe, G. and Steptoe, A. (2016) The interaction between systemic inflammation and psychosocial stress in the association with cardiac troponin elevation: a new approach to risk assessment and disease prevention. Preventive Medicine, 93, pp. 46-52. (doi: 10.1016/j.ypmed.2016.09.018) (PMID:27663429) (PMCID:PMC5126095)

Steptoe, A., Kivimäki, M., Lowe, G., Rumley, A. and Hamer, M. (2016) Blood pressure and fibrinogen responses to mental stress as predictors of incident hypertension over an 8-year period. Annals of Behavioral Medicine, 50(6), pp. 898-906. (doi: 10.1007/s12160-016-9817-5) (PMID:27401000) (PMCID:PMC5126198)

Wang, X., Chappell, F. M., Valdes Hernandez, M., Lowe, G., Rumley, A., Shuler, K., Doubal, F. and Wardlaw, J. M. (2016) Endothelial function, inflammation, thrombosis, and basal ganglia perivascular spaces in patients with stroke. Journal of Stroke and Cerebrovascular Diseases, 25(12), pp. 2925-2931. (doi: 10.1016/j.jstrokecerebrovasdis.2016.08.007) (PMID:27576214) (PMCID:PMC5176093)

Herder, C. et al. (2016) Biomarkers of subclinical inflammation and increases in glycaemia, insulin resistance and beta-cell function in non-diabetic individuals: the Whitehall II study. European Journal of Endocrinology, 175, pp. 367-377. (doi: 10.1530/EJE-16-0528) (PMID:27491375)

van Loon, J. et al. (2016) Genome-wide association studies identify genetic loci for low von Willebrand factor levels. European Journal of Human Genetics, 24(7), pp. 1035-1040. (doi: 10.1038/ejhg.2015.222) (PMID:26486471)

Lazzarino, A.I., Hamer, M., Gaze, D., Collinson, P., Rumley, A., Lowe, G. and Steptoe, A. (2015) The association between fibrinogen reactivity to mental stress and high-sensitivity cardiac troponin T in healthy adults. Psychoneuroendocrinology, 59, pp. 37-48. (doi: 10.1016/j.psyneuen.2015.05.002) (PMID:26010862)

Wiseman, S. J., Doubal, F. N., Chappell, F. M., Valdés-Hernández, M. C., Wang, X., Rumley, A., Lowe, G. D.O., Dennis, M. S. and Wardlaw, J. M. (2015) Plasma biomarkers of inflammation, endothelial function andhemostasis in cerebral small vessel disease. Cerebrovascular Diseases, 40(3-4), pp. 157-164. (doi: 10.1159/000438494) (PMID:26279056)

Maino, A., Siegerink, B., Lotta, L.A., Crawley, J.T.B., le Cessie, S., Leebeek, F.W.G., Lane, D. A., Lowe, G.D.O., Peyvandi, F. and Rosendaal, F.R. (2015) Plasma ADAMTS-13 levels and the risk of myocardial infarction: an individual patient data meta-analysis. Journal of Thrombosis and Haemostasis, 13(8), pp. 1396-1404. (doi: 10.1111/jth.13032) (PMID:26073931)

Virtanen, M. et al. (2015) Interleukin-6 as a predictor of symptom resolution in psychological distress: a cohort study. Psychological Medicine, 45(10), pp. 2137-2144. (doi: 10.1017/S0033291715000070) (PMID:25697833)

Akbaraly, T. N., Shipley, M. J., Ferrie, J. E., Virtanen, M., Lowe, G., Hamer, M. and Kivimaki, M. (2015) Long-term adherence to healthy dietary guidelines and chronic inflammation in the prospective Whitehall II study. American Journal of Medicine, 128(2), 152-160.e4. (doi: 10.1016/j.amjmed.2014.10.002)

Loeffen, R., Winckers, K., Ford, I. , Jukema, J. W., Robertson, M., Stott, D. J. , Spronk, H. M., ten Cate, H. and Lowe, G. (2015) Associations between thrombin generation and the risk of cardiovascular disease in elderly patients: results from the PROSPER study. Journals of Gerontology Series A: Biological Sciences and Medical Sciences, 70(8), pp. 982-988. (doi: 10.1093/gerona/glu228) (PMID:25540034)

Wannamethee, S. G., Whincup, P. H., Lennon, L., Papacosta, O. and Lowe, G. D. (2014) Associations between fibrin D-dimer, markers of inflammation, incident self-reported mobility limitation, and all-cause mortality in older men. Journal of the American Geriatrics Society, 62(12), pp. 2357-2362. (doi: 10.1111/jgs.13133)

Lowe, G. and Rumley, A. (2014) The relevance of coagulation in cardiovascular disease: what do the biomarkers tell us? Thrombosis and Haemostasis, 112(5), pp. 860-867. (doi: 10.1160/TH14-03-0199)

ten Cate, H. and Lowe, G. (2014) Coagulation proteases and cardiovascular disease. Thrombosis and Haemostasis, 112(5), pp. 858-859. (doi: 10.1160/TH14-09-0781)

Cheng, K., Giebaly, D., Campbell, A., Rumley, A. and Lowe, G. (2014) Systemic effects of polymethylmethycrylate in total knee replacement: a prospective case-control study. Bone and Joint Research, 3(4), pp. 108-116. (doi: 10.1302/2046-3758.34.2000230) (PMID:24740649) (PMCID:PMC4036303)

Lowe, G. et al. (2014) Circulating inflammatory markers and the risk of vascular complications and mortality in people with type 2 diabetes and cardiovascular disease or risk factors: the ADVANCE Study. Diabetes, 63(3), pp. 1115-1123. (doi: 10.2337/db12-1625)

Baumert, J. et al. (2014) No evidence for genome-wide interactions on plasma fibrinogen by smoking, alcohol consumption and body mass index: results from meta-analyses of 80,607 subjects. PLoS ONE, 9(12), e111156. (doi: 10.1371/journal.pone.0111156) (PMID:25551457) (PMCID:PMC4281156)

Huang, J. et al. (2014) Genome-wide association study for circulating tissue plasminogen activator levels and functional follow-up implicates endothelial STXBP5 and STX2. Arteriosclerosis, Thrombosis, and Vascular Biology, 34(5), pp. 1093-1101. (doi: 10.1161/ATVBAHA.113.302088)

Kivimäki, M. et al. (2014) Long-term inflammation increases risk of common mental disorder: a cohort study. Molecular Psychiatry, 19(2), pp. 149-150. (doi: 10.1038/mp.2013.35)

Tabassum, F., Kumari, M., Rumley, A., Power, C., Strachan, D. P. and Lowe, G. (2014) Lifecourse social position and D-dimer; findings from the 1958 British birth cohort. PLoS ONE, 9(5), e93277. (doi: 10.1371/journal.pone.0093277) (PMID:24809471) (PMCID:PMC4014469)

Gaunt, T.R. et al. (2013) Gene-centric association signals for haemostasis and thrombosis traits identified with the HumanCVD BeadChip. Thrombosis and Haemostasis, 110(5), pp. 995-1003. (doi: 10.1160/TH13-02-0087)

Khan, M.M., Tait, R.C. , Kerr, R., Ludlam, C.A., Lowe, G.D.O., Murray, W. and Watson, H.G. (2013) Hepatitis C infection and outcomes in the Scottish haemophilia population. Haemophilia, 19(6), pp. 870-875. (doi: 10.1111/hae.12218) (PMID:23786361)

Peters, S.A.E., Woodward, M., Rumley, A., Koenig, W., Tunstall-Pedoe, H. and Lowe, G.D.O. (2013) Direct comparisons of three alternative plasma fibrinogen assays with the von Clauss assay in prediction of cardiovascular disease and all-causes mortality: the Scottish heart health extended cohort. British Journal of Haematology, 162(3), pp. 392-399. (doi: 10.1111/bjh.12389)

Smid, M., Dielis, A. W. J. H., Spronk, H. M. H. S., Rumley, A., van Oerle, R., Woodward, M., ten Cate, H. and Lowe, G. (2013) Thrombin generation in the Glasgow myocardial infarction study. PLoS ONE, 8(6), e66977. (doi: 10.1371/journal.pone.0066977) (PMID:23826181) (PMCID:PMC3691168)

Gaunt, T.R., Lowe, G.D.O., Lawlor, D.A., Casas, J.-P. and Day, I.N.M. (2013) A gene-centric analysis of activated partial thromboplastin time and activated protein C resistance using the HumanCVD focused genotyping array. European Journal of Human Genetics, 21(7), pp. 779-783. (doi: 10.1038/ejhg.2012.242)

Inglis, S.C., Lewsey, J.D. , Lowe, G.D.O., Jhund, P. , Gillies, M., Stewart, S., Capewell, S., MacIntyre, K. and McMurray, J.J.V. (2013) Angina and intermittent claudication in 7403 participants of the 2003 Scottish Health Survey: impact on general and mental health, quality of life and five-year mortality. International Journal of Cardiology, 167(5), pp. 2149-2155. (doi: 10.1016/j.ijcard.2012.05.099)

Willeit, P., Thompson, A., Aspelund, T., Rumley, A., Eiriksdottir, G., Lowe, G., Gudnason, V. and Di Angelantonio, E. (2013) Hemostatic factors and risk of coronary heart disease in general populations: new prospective study and updated meta-analyses. PLoS ONE, 8(2), e55175. (doi: 10.1371/journal.pone.0055175) (PMID:23408959) (PMCID:PMC3567058)

Kaptoge, S. et al. (2012) C-reactive protein, fibrinogen, and cardiovascular disease prediction. New England Journal of Medicine, 367(14), pp. 1310-1320. (doi: 10.1056/NEJMoa1107477)

Lowe, G.D.O. (2012) Epidemiology of venous thromboembolism: the need for large (including prospective) studies and meta-analyses. Journal of Thrombosis and Haemostasis, 10(10), pp. 2186-2188. (doi: 10.1111/j.1538-7836.2012.04882.x)

Hingorani, A.D., Sofat, R., Morris, R.W., Whincup, P., Lowe, G.D., Mindell, J., Sattar, N. , Casas, J.P. and Shah, T. (2012) Is it important to measure or reduce C-reactive protein in people at risk of cardiovascular disease? European Heart Journal, 33(18), pp. 2258-2264. (doi: 10.1093/eurheartj/ehs168)

Paul, L. et al. (2012) Hematocrit predicts long-term mortality in a nonlinear and sex-specific manner in hypertensive adults. Hypertension, 60(3), pp. 631-638. (doi: 10.1161/HYPERTENSIONAHA.112.191510)

Inglis, S.C., Lewsey, J.D. , Chandler, D., Byrne, D.S., Lowe, G.D.O. and MacIntyre, K. (2012) Sex-specific time trends in first admission to hospital for peripheral artery disease in Scotland 1991-2007. British Journal of Surgery, 99(5), pp. 680-687. (doi: 10.1002/bjs.8686)

Ghebre, M.A., Wannamethee, S.G., Rumley, A., Whincup, P.H., Lowe, G.D.O. and Morris, R.W. (2012) Prospective study of seasonal patterns in hemostatic factors in older men and their relation to excess winter coronary heart disease deaths. Journal of Thrombosis and Haemostasis, 10(3), pp. 352-358. (doi: 10.1111/j.1538-7836.2012.04617.x)

Wannamethee, S.G., Papacosta, O., Lawlor, D.A., Whincup, P.H., Lowe, G.D., Ebrahim, S. and Sattar, N. (2012) Do women exhibit greater differences in established and novel risk factors between diabetes and non-diabetes than men? The British Regional Heart Study and British Women’s Heart Health Study. Diabetologia, 55(1), pp. 80-87. (doi: 10.1007/s00125-011-2284-4)

Wennberg, P., Wensley, F., Di Angelantonio, E., Johansson, L., Boman, K., Rumley, A., Lowe, G., Hallmans, G., Danesh, J. and Jansson, J.-H. (2012) Haemostatic and inflammatory markers are independently associated with myocardial infarction in men and women. Thrombosis Research, 129(1), pp. 68-73. (doi: 10.1016/j.thromres.2011.05.015)

Nüesch, E., Dale, C.E., Amuzu, A., Kuper, H., Bowling, A., Ploubidis, G.B., Lowe, G., Rumley, A., Ebrahim, S. and Casas, J.P. (2012) Inflammation, coagulation and risk of locomotor disability in elderly women: findings from the British Women’s Heart and Health Study. European Journal of Epidemiology, 27(8), pp. 633-645. (doi: 10.1007/s10654-012-9706-6)

Whiteley, W., Wardlaw, J., Dennis, M., Lowe, G., Rumley, A., Sattar, N. , Welsh, P. , Green, A., Andrews, M. and Sandercock, P. (2012) The use of blood biomarkers to predict poor outcome after acute transient ischemic attack or ischemic stroke. Stroke, 43(1), pp. 86-91. (doi: 10.1161/STROKEAHA.111.634089)

Marioni, R.E. et al. (2011) Genetic associations between fibrinogen and cognitive performance in three Scottish cohorts. Behavior Genetics, 41(5), pp. 691-699. (doi: 10.1007/s10519-011-9449-2)

Jefferis, B.J., Whincup, P.H., Welsh, P. , Wannathamee, S.G., Rumley, A., Lawlor, D.A., Ebrahim, S. and Lowe, G.D.O. (2011) Prospective study of circulating soluble CD40 ligand concentrations and the incidence of cardiovascular disease in a nested prospective case-control study of older men and women. Journal of Thrombosis and Haemostasis, 9(8), pp. 1452-1459. (doi: 10.1111/j.1538-7836.2011.04415.x)

Quinn, T.J. , Gallacher, J., Deary, I.J., Lowe, G.D.O., Fenton, C. and Stott, D.J. (2011) Association between circulating hemostatic measures and dementia or cognitive impairment: systematic review and meta-analyzes. Journal of Thrombosis and Haemostasis, 9(8), pp. 1475-1482. (doi: 10.1111/j.1538-7836.2011.04403.x)

Wannamethee, S. G., Welsh, P. , Lowe, G. D., Gudnason, V., Di Angelantonio, E., Lennon, L., Rumley, A., Whincup, P. H. and Sattar, N. (2011) N-terminal pro-brain natriuretic peptide is a more useful predictor of cardiovascular disease risk than C-reactive protein in older men with and without pre-existing cardiovascular disease. Journal of the American College of Cardiology, 58(1), pp. 56-64. (doi: 10.1016/j.jacc.2011.02.041)

Bolton, C.E. et al. (2011) The CRP genotype, serum levels and lung function in men: the Caerphilly Prospective Study. Clinical Science, 120(8), pp. 347-355. (doi: 10.1042/CS20100504)

Wensley, F. et al. (2011) Association between C reactive protein and coronary heart disease: mendelian randomisation analysis based on individual participant data. British Medical Journal, 342, d548-d548. (doi: 10.1136/bmj.d548)

Calvin, C.M., Batty, G.D., Lowe, G.D.O. and Deary, I.J. (2011) Childhood intelligence and midlife inflammatory and hemostatic biomarkers: The National Child Development Study (1958) cohort. Health Psychology, 30(6), pp. 710-718. (doi: 10.1037/a0023940)

Freeman, D. J. et al. (2011) Incident venous thromboembolic events in the Prospective Study of Pravastatin in the Elderly at Risk (PROSPER). BMC Geriatrics, 11, 8. (doi: 10.1186/1471-2318-11-8) (PMID:21342490) (PMCID:PMC3053238)

Jefferis, B.J.M.H. et al. (2011) Interleukin 18 and coronary heart disease: Prospective study and systematic review. Atherosclerosis, 217(1), pp. 227-233. (doi: 10.1016/j.atherosclerosis.2011.03.015)

Lowe, G. (2011) Can haemostatic factors predict atherothrombosis? Internal and Emergency Medicine, 6(6), pp. 497-501. (doi: 10.1007/s11739-011-0536-4)

Ngai, L.-Y., Stocks, N., Sparrow, J. M., Patel, R., Rumley, A., Lowe, G., Davey Smith, G. and Ben-Shlomo, Y. (2011) The prevalence and analysis of risk factors for age-related macular degeneration: 18-year follow-up data from the Speedwell eye study, United Kingdom. Eye, 25(6), pp. 784-793. (doi: 10.1038/eye.2011.56)

Rudnicka, A.R., Rumley, A., Whincup, P.H., Lowe, G.D. and Strachan, D.P. (2011) Sex differences in the relationship between inflammatory and hemostatic biomarkers and metabolic syndrome: British 1958 Birth Cohort. Journal of Thrombosis and Haemostasis, 9(12), pp. 2337-2344. (doi: 10.1111/j.1538-7836.2011.04517.x)

Smith, N. L. et al. (2011) Genetic predictors of fibrin D-Dimer levels in healthy adults. Circulation, 123(17), pp. 1864-1872. (doi: 10.1161/CIRCULATIONAHA.110.009480)

Stephens, J.W. et al. (2011) Effects of short-term therapy with glibenclamide and repaglinide on incretin hormones and oxidative damage associated with postprandial hyperglycaemia in people with type 2 diabetes mellitus. Diabetes Research and Clinical Practice, 94(2), pp. 199-206. (doi: 10.1016/j.diabres.2011.07.014)

Whiteley, W., Jackson, C., Lewis, S., Lowe, G., Rumley, A., Sandercock, P., Wardlaw, J., Dennis, M. and Sudlow, C. (2011) Association of circulating inflammatory markers with recurrent vascular events after stroke: a prospective cohort study. Stroke, 42(1), pp. 10-16. (doi: 10.1161/STROKEAHA.110.588954)

Whiteley, W. et al. (2011) Blood biomarkers for the diagnosis of acute cerebrovascular diseases: a prospective cohort study. Cerebrovascular Diseases, 32(2), pp. 141-147. (doi: 10.1159/000328517)

Zabaneh, D. et al. (2011) Genetic Variants Associated with von Willebrand Factor Levels in Healthy Men and Women Identified Using the HumanCVD BeadChip. Annals of Human Genetics, 75(4), pp. 456-467. (doi: 10.1111/j.1469-1809.2011.00654.x)

Lowe, G.D. and Sandercock, P. (2010) Does acetyl salicylic acid (ASA) have a role in the prevention of venous thromboembolism? British Journal of Haematology, 148(2), pp. 339-340. (doi: 10.1111/j.1365-2141.2009.07933.x)

Clark, P., Wu, O. , Greer, I.A. and Lowe, G.D.O. (2010) Venous thrombosis prevention more than just guidelines. British Journal of Haematology, 149(1), pp. 50-54. (doi: 10.1111/j.1365-2141.2010.08080.x)

Fogarty, A.W., Lewis, S.A., McKeever, T.M., Lowe, G.D.O., Clark, L., Britton, J. and Reitsma, P.H. (2010) The association between blood coagulation activity and lung function: a population-based study. PLoS ONE, 5(11), e15014. (doi: 10.1371/journal.pone.0015014) (PMID:21103357) (PMCID:PMC2982817)

Gallacher, J., Bayer, A., Lowe, G., Fish, M., Pickering, J., Pedro, S., Dunstan, F., White, J., Yarnell, J. and Ben Shlomo, Y. (2010) Is Sticky Blood Bad for the Brain? Hemostatic and Inflammatory Systems and Dementia in the Caerphilly Prospective Study. Arteriosclerosis, Thrombosis, and Vascular Biology, 30(3), 599-U459. (doi: 10.1161/ATVBAHA.109.197368)

Hamer, M., Stamatakis, E., Kivimaki, M., Lowe, G. D. and Batty, G. D. (2010) Objectively Measured Secondhand Smoke Exposure and Risk of Cardiovascular Disease. Journal of the American College of Cardiology, 56(1), pp. 18-23. (doi: 10.1016/j.jacc.2010.03.032)

Houlihan, L. M. et al. (2010) Common Variants of Large Effect in F12, KNG1, and HRG Are Associated with Activated Partial Thromboplastin Time. American Journal of Human Genetics, 86(4), pp. 626-631. (doi: 10.1016/j.ajhg.2010.02.016)

Jefferis, B. J. et al. (2010) Secondhand smoke (SHS) exposure is associated with circulating markers of inflammation and endothelial function in adult men and women. Atherosclerosis, 208(2), pp. 550-556. (doi: 10.1016/j.atherosclerosis.2009.07.044)

Jefferis, B. J. et al. (2010) Prospective study of matrix metalloproteinase-9 and risk of myocardial infarction and stroke in older men and women. Atherosclerosis, 208(2), pp. 557-563. (doi: 10.1016/j.atherosclerosis.2009.08.018)

Lowe, G. (2010) What is the clinical relevance of the prothrombin G20210A mutation? Atherosclerosis, 208(2), pp. 330-331. (doi: 10.1016/j.atherosclerosis.2009.11.002)

Lowe, G. D. O. (2010) Fibrinogen Assays for Cardiovascular Risk Assessment. Clinical Chemistry, 56(5), pp. 693-695. (doi: 10.1373/clinchem.2010.145342)

Lowe, G. D. O. (2010) Management of deep vein thrombosis to reduce the incidence of post-thrombotic syndrome. Phlebology, 25(Supple), pp. 9-13. (doi: 10.1258/phleb.2010.010s02)

Marioni, R. E., Deary, I. J., Strachan, M. W., Lowe, G. D., Rumley, A., Murray, G. D. and Price, J. F. (2010) Blood rheology and cognition in the Edinburgh Type 2 Diabetes Study. Age and Ageing, 39(3), pp. 354-359. (doi: 10.1093/ageing/afq021)

Marioni, R. E. et al. (2010) Association Between Raised Inflammatory Markers and Cognitive Decline in Elderly People With Type 2 Diabetes The Edinburgh Type 2 Diabetes Study. Diabetes, 59(3), pp. 710-713. (doi: 10.2337/db09-1163)

Marioni, R.E. et al. (2010) Genetic variants associated with altered plasma levels of C-reactive protein are not associated with late-life cognitive ability in four Scottish samples. Behavior Genetics, 40(1), pp. 3-11. (doi: 10.1007/s10519-009-9302-z)

McEniery, C. M., Spratt, M., Munnery, M., Yarnell, J., Lowe, G. D., Rumley, A., Gallacher, J., Ben Shlomo, Y., Cockcroft, J. R. and Wilkinson, I. B. (2010) An Analysis of Prospective Risk Factors for Aortic Stiffness in Men 20-Year Follow-Up From the Caerphilly Prospective Study. Hypertension, 56(1), pp. 36-43. (doi: 10.1161/HYPERTENSIONAHA.110.150896)

Patterson, C. C., Smith, A. E., Yarnell, J. W. G., Rumley, A., Ben Shlomo, Y. and Lowe, G.D.O. (2010) The associations of interleukin-6 (IL-6) and downstream inflammatory markers with risk of cardiovascular disease: The Caerphilly Study. Atherosclerosis, 209(2), pp. 551-557. (doi: 10.1016/j.atherosclerosis.2009.09.030)

Rafnsson, S., Deary, I.J., Whiteman, M.C., Rumley, A., Lowe, G.D.O. and Fowkes, F.G.R. (2010) Haemorheological predictors of cognitive decline: the Edinburgh Artery Study. Age and Ageing, 39(2), pp. 217-222. (doi: 10.1093/ageing/afp227)

Stott, D.J. et al. (2010) Activation of Hemostasis and Decline in Cognitive Function in Older People. Arteriosclerosis, Thrombosis, and Vascular Biology, 30(3), pp. 605-611. (doi: 10.1161/ATVBAHA.109.199448)

Tabak, A. G., Kivimaki, M., Brunner, E. J., Lowe, G.D., Jokela, M., Akbaraly, T. N., Singh-Manoux, A., Ferrie, J. E. and Witte, D. R. (2010) Changes in C-reactive protein levels before type 2 diabetes and cardiovascular death: the Whitehall II study. European Journal of Endocrinology, 163(1), pp. 89-95. (doi: 10.1530/EJE-10-0277)

Wannamethee, S. G., Shaper, A. G., Rumley, A., Sattar, N. , Whincup, P. H., Thomas, M. C. and Lowe, G.D. (2010) Lung Function and Risk of Type 2 Diabetes and Fatal and Nonfatal Major Coronary Heart Disease Events: Possible Associations With Inflammation. Diabetes Care, 33(9), pp. 1990-1996. (doi: 10.2337/dc10-0324)

Weir, R.A.P., Balmain, S., Steedman, T., Ng, L. L., Squire, I. B., Rumley, A., Dargie, H.J. and Lowe, G.D.O. (2010) Tissue plasminogen activator antigen predicts medium-term left ventricular end-systolic volume after acute myocardial infarction. Journal of Thrombosis and Thrombolysis, 29(4), pp. 421-428. (doi: 10.1007/s11239-009-0383-6)

Welsh, P. , Woodward, M., Rumley, A., MacMahon, S. and Lowe, G.D. (2010) Does interleukin-18 or tumour necrosis factor-alpha have an independent association with the risk of coronary heart disease? Results from a prospective study in New Zealand. Cytokine, 50(1), pp. 94-98. (doi: 10.1016/j.cyto.2009.12.014)

Wennberg, P., Wensley, F., Johansson, L., Boman, K., Di Angelantonio, E., Rumley, A., Lowe, G., Hallmans, G. and Jansson, J. H. (2010) Reduced risk of myocardial infarction related to active commuting: inflammatory and haemostatic effects are potential major mediating mechanisms. European Journal of Cardiovascular Prevention and Rehabilitation, 17(1), pp. 56-62. (doi: 10.1097/HJR.0b013e32832f3b11)

Woodward, M., Welsh, P. , Rumley, A., Tunstall-Pedoe, H. and Lowe, G. D. O. (2010) Do inflammatory biomarkers add to the discrimination of cardiovascular disease after allowing for social deprivation? Results from a 10-year cohort study in Glasgow, Scotland. European Heart Journal, 31(21), pp. 2669-2675. (doi: 10.1093/eurheartj/ehp115)

Shepherd, J., Lowe, G., Ford, I. and Robertson, M. (2009) Correcting for multivariate measurement error by regression calibration in meta-analyses of epidemiological studies. Statistics in Medicine, 28(7), pp. 1067-1092. (doi: 10.1002/sim.3530)

Stott, D.J., Welsh, P.I., Rumley, A., Robertson, M., Ford, I. , Sattar, N.A., Westendorp, R.G.J., Jukema, J.W., Cobbe, S. and Lowe, G.D. (2009) Adipocytokines and risk of stroke in older people: a nested case-control study. International Journal of Epidemiology, 38(1), pp. 253-261. (doi: 10.1093/ije/dyn215)

Dehghan, A. et al. (2009) Association of Novel Genetic Loci With Circulating Fibrinogen Levels A Genome-Wide Association Study in 6 Population-Based Cohorts. Circulation: Cardiovascular Genetics, 2(2), 125-U91. (doi: 10.1161/CIRCGENETICS.108.825224)

Fraser, A., May, M., Lowe, G., Rumley, A., Davey Smith, G., Ebrahim, S. and Lawlor, D. (2009) Interleukin-6 and incident coronary heart disease: Results from the British Women's Heart and Health Study. Atherosclerosis, 202(2), pp. 567-572. (doi: 10.1016/j.atherosclerosis.2008.04.048)

Gimeno, D. et al. (2009) Associations of C-reactive protein and interleukin-6 with cognitive symptoms of depression: 12-year follow-up of the Whitehall II study. Psychological Medicine, 39(3), pp. 413-423.

Heikkila, K., Harris, R., Lowe, G., Rumley, A., Yarnell, J., Gallacher, J., Ben Shlomo, Y., Ebrahim, S. and Lawlor, D. (2009) Associations of circulating C-reactive protein and interleukin-6 with cancer risk: findings from two prospective cohorts and a meta-analysis. Cancer Causes and Control, 20(1), pp. 15-26.

Jefferis, B. et al. (2009) Circulating TNF alpha levels in older men and women do not show independent prospective relations with MI or stroke. Atherosclerosis, 205(1), pp. 302-308.

Lowe, G. (2009) Common risk factors for both arterial and venous thrombosis. Sang Thrombose Vaisseaux, 21(1), pp. 31-38.

Marioni, R. et al. (2009) Peripheral Levels of Fibrinogen, C-Reactive Protein, and Plasma Viscosity Predict Future Cognitive Decline in Individuals Without DementiaPeripheral Neuropathies Biomarkers for Axonal Damage in Immune-Mediated Neuropathy. Psychosomatic Medicine, 71(8), pp. 901-906.

Ramsay, S., Morris, R., Whincup, P., Papacosta, O., Rumley, A., Lennon, L., Lowe, G.D. and Wannamethee, S. (2009) Socioeconomic inequalities in coronary heart disease risk in older age: contribution of established and novel coronary risk factors. Journal of Thrombosis and Haemostasis, 7(11), pp. 1779-1786.

Sanders, J., Hawe, E., Brull, D., Hubbart, C., Lowe, G.D., Rumley, A., Humphries, S. and Montgomery, H. (2009) Higher IL-6 levels but not IL6-174G > C or-572G > C genotype are associated with post-operative complication following coronary artery bypass graft (CABG) surgery. Atherosclerosis, 204(1), pp. 196-201.

Sanderson, S., Kumari, M., Brunner, E., Miller, M., Rumley, A., Lowe, G.D., Marmot, M. and Humphries, S. (2009) Association between IL6 gene variants-174G > C and-572G > C and serum IL-6 levels: Interactions with social position in the Whitehall II cohort. Atherosclerosis, 204(2), pp. 459-464.

Sattar, N.A. et al. (2009) Are markers of inflammation more strongly associated with risk for fatal than for nonfatal vascular events? PLoS Medicine, 6(6), e1000099. (doi: 10.1371/journal.pmed.1000099)

Schumacher, W., Cockcroft, J., Timpson, N., McEniery, C., Gallacher, J., Rumley, A., Lowe, G., Davey Smith, G., Wilkinson, I. and Ben Shlomo, Y. (2009) Association Between C-Reactive Protein Genotype, Circulating Levels, and Aortic Pulse Wave Velocity. Hypertension, 53(2), pp. 150-157. (doi: 10.1161/HYPERTENSIONAHA.108.117622)

Shah, T. et al. (2009) Critical appraisal of CRP measurement for the prediction of coronary heart disease events: new data and systematic review of 31 prospective cohorts. International Journal of Epidemiology, 38(1), pp. 217-231.

Wannamethee, S., Whincup, P., Shaper, A., Rumley, A., Lennon, L. and Lowe, G.D. (2009) Circulating inflammatory and hemostatic biomarkers are associated with risk of myocardial infarction and coronary death, but not angina pectoris, in older men. Journal of Thrombosis and Haemostasis, 7(10), pp. 1605-1611.

Welsh, P., Barber, M., Langhorne, P., Rumley, A., Lowe, G. and Stott, D. (2009) Associations of Inflammatory and Haemostatic Biomarkers with Poor Outcome in Acute Ischaemic Stroke. Cerebrovascular Diseases, 27(3), pp. 247-253. (doi: 10.1159/000196823)

Welsh, P., Woodward, M., Rumley, A. and Lowe, G.D. (2009) Associations of circulating TNF alpha and IL-18 with myocardial infarction and cardiovascular risk markers: The Glasgow Myocardial Infarction Study. Cytokine, 47(2), pp. 143-147.

Whiteley, W., Jackson, C., Lewis, S., Lowe, G.D., Rumley, A., Sandercock, P., Wardlaw, J., Dennis, M. and Sudlow, C. (2009) Inflammatory markers and poor outcome after stroke: a prospective cohort study and systematic review of interleukin-6. PLoS Medicine, 6(9), e1000145. (doi: 10.1371/journal.pmed.1000145)

Wild, S., Byrne, C., Tzoulaki, I., Lee, A., Rumley, A., Lowe, G. and Fowkes, F. (2009) Metabolic syndrome, haemostatic and inflammatory markers, cerebrovascular and peripheral arterial disease: The Edinburgh Artery Study. Atherosclerosis, 203(2), pp. 604-609.

Woodward, M., Tunstall-Pedoe, H., Rumley, A. and Lowe, G.D. (2009) Does fibrinogen add to prediction of cardiovascular disease? Results from the Scottish Heart Health Extended Cohort Study. British Journal of Haematology, 146(4), pp. 442-446.

Brunner, E.J. et al. (2008) Inflammation, insulin resistance, and diabetes-mendelian randomization using CRP haplotypes points upstream. PLoS Medicine, 5(8), e155. (doi: 10.1371/journal.pmed.0050155)

Welsh, P. , Lowe, G.D., Chalmers, J., Campbell, D., Rumley, A., Neal, B.C., MacMahon, S.W. and Woodward, M. (2008) Associations of proinflammatory cytokines with the risk of recurrent stroke. Stroke, 39(8), pp. 2226-2230. (doi: 10.1161/STROKEAHA.107.504498)

Danesh, J. et al. (2008) Long-term interleukin-6 levels and subsequent risk of coronary heart disease: Two new prospective studies and a systematic review. PLoS Medicine, 5(4), e78. (doi: 10.1371/journal.pmed.0050078)

Bennet, A., Di Angelantonio, E., Erqou, S., Eiriksdottir, G., Sigurdsson, G., Woodward, M., Rumley, A., Lowe, G., Danesh, J. and Gudnason, V. (2008) Lipoprotein(a) levels and risk of future coronary heart disease. Archives of Internal Medicine, 168(6), pp. 598-608. (doi: 10.1001/archinte.168.6.598) (PMID:18362252)

Canonico, M., Plu-Bureau, G., Lowe, G. and Scarabin, P. (2008) Hormone replacement therapy and risk of venous thromboembolism in postmenopausal women: systematic review and meta-analysis. British Medical Journal, 336(7655), 1227-+. (doi: 10.1136/bmj.39555.441944.BE)

Crawley, J., Lane, D., Woodward, M., Rumley, A. and Lowe, G. (2008) Evidence that high von Willebrand factor and low ADAMTS-13 levels independently increase the risk of a non-fatal heart attack. Journal of Thrombosis and Haemostasis, 6(4), pp. 583-588. (doi: 10.1111/j.1538-7836.2008.02902.x)

Fraser, A., Fraser, A., Hughes, R., McCarthy, A., Tilling, K., Davies, D., Rumley, A., Lowe, G., Smith, G. and Ben Shlomo, Y. (2008) Early life growth and hemostatic factors. American Journal of Epidemiology, 168(2), pp. 179-187.

Freeman, D., Tham, K., Brown, E., Rumley, A., Lowe, G. and Greer, I. (2008) Placental corticotrophin-releasing hormone RNA and microparticles in maternal plasma are not measures of placental shedding of debris: reply to a rebuttal. Journal of Thrombosis and Haemostasis, 6(10), pp. 1838-1839.

Freeman, D., Tham, K., Brown, E., Rumley, A., Lowe, G. and Greer, I. (2008) Fetal corticotrophin-releasing hormone mRNA, but not phosphatidylserine-exposing microparticles, in maternal plasma are associated with factor VII activity in pre-eclampsia. Journal of Thrombosis and Haemostasis, 6(3), pp. 421-427. (doi: 10.1111/j.1538-7836.2007.02882.x)

Kelly, B., Wales, A., Wilson, A., Jackson, B., Leiberman, D.P. and Lowe, G.D. (2008) Getting research evidence into practice. Health Bulletin, 59, pp. 57-59.

Lawlor, D.A. et al. (2008) The association of C-reactive protein and CRP genotype with coronary heart disease: findings from five studies with 4,610 cases amongst 18,637 participants. PLoS ONE, 3(8), e3011. (doi: 10.1371/journal.pone.0003011) (PMID:18714384) (PMCID:PMC2507759)

Lowe, G. (2008) Coagulation factors, activation markers and risk of coronary heart disease: the Northwick Park Heart Studies. Journal of Thrombosis and Haemostasis, 6(2), pp. 256-258.

Lowe, G. (2008) Coagulation, genotypes and recurrent cardiovascular events: what further studies are required? Journal of Thrombosis and Haemostasis, 6(5), pp. 717-719. (doi: 10.1111/j.1538-7836.2008.02947.x)

Lowe, G. (2008) Thromboprophylaxis for patients at high risk of VTE. Lancet, 372(9643), pp. 1037-1038.

Lowe, G. and Ludlam, C. (2008) Less severe bleeding in hemophilia B than in hemophilia A. Journal of Thrombosis and Haemostasis, 6(11), pp. 1982-1983. (doi: 10.1111/j.1538-7836.2008.03126.x)

Poller, L. et al. (2008) A multicentre randomised clinical endpoint study of PARMA 5 computer-assisted oral anticoagulant dosage. British Journal of Haematology, 143(2), pp. 274-283.

Poller, L. et al. (2008) An international multicenter randomized study of computer-assisted oral anticoagulant dosage vs. medical staff dosage. Journal of Thrombosis and Haemostasis, 6(6), pp. 935-943.

Ramsay, S., Lowe, G., Whincup, P., Rumley, A., Morris, R. and Wannamethee, S. (2008) Relationships of inflammatory and haemostatic markers with social class: Results from a population-based study of older men. Atherosclerosis, 197(2), pp. 654-661.

Tabassum, F., Kumari, M., Rumley, A., Lowe, G., Power, C. and Strachan, D. (2008) Effects of socioeconomic position on inflammatory and hemostatic markers: A life-course analysis in the 1958 British birth cohort. American Journal of Epidemiology, 167(11), pp. 1332-1341.

Wannamethee, S., Sattar, N. , Rumley, A., Whincup, P., Lennon, L. and Lowe, G. (2008) Tissue plasminogen activator, von Willebrand factor, and risk of type 2 diabetes in older men. Diabetes Care, 31(5), pp. 995-1000.

Welsh, P.I. , Whincup, P.H., Papacosta, O., Wannamethee, S.G., Lennon, L., Thomson, A.H., Thomson, A.J., Rumley, A. and Lowe, G.D. (2008) Serum matrix metalloproteinase-9 and coronary heart disease: a prospective study in middle-aged men. QJM: An International Journal of Medicine, 101(10), pp. 785-791.

Welsh, P. , Woodward, M. and Lowe, G. (2008) Associations of plasma pro-inflammatory cytokines, fibrinogen, viscosity and C-reactive protein with cardiovascular risk factors and social deprivation: the fourth Glasgow MONICA study. British Journal of Haematology, 141(6), pp. 852-861.

Zhao, X., Courtney, J., Yin, H., West, R. and Lowe, G. (2008) Blood interactions with plasticised poly (vinyl chloride): influence of surface modification. Journal of Materials Science: Materials in Medicine, 19(2), pp. 713-719.

Lara, J.J., Economou, M., Wallace, A.M., Rumley, A., Lowe, G., Slater, C., Caslake, M., Sattar, N. and Lean, M.E.J. (2007) Benefits of salmon eating on traditional and novel vascular risk factors in young, non-obese healthy subjects. Atherosclerosis, 193(1), pp. 213-221. (doi: 10.1016/j.atherosclerosis.2006.06.018)

Brown, K., Cherry, L., Lowe, G., Rumley, A., Sattar, N. , Tchernova, J., Wannamethee, S. and Whincup, P. (2007) Associations of adiponectin with metabolic and vascular risk parameters in the British Regional Heart Study reveal stronger links to insulin resistance-related than to coronory heart disease risk-related parameters. International Journal of Obesity, 31, pp. 1089-1098. (doi: 10.1038/sj.ijo.0803544)

Cherry, L., Lowe, G., Rumley, A., Sattar, N. , Wannamethee, S. and Whincup, P. (2007) Adipokines and risk of type 2 diabetes in older men. Diabetes Care, 30, pp. 1200-1205.

Deary, I., Fowkes, F., Lowe, G., Rafnsson, S., Rumley, A., Smith, F. and Whiteman, M. (2007) Cognitive decline and markers of inflammation and hemostasis: The Edinburgh Artery Study. Journal of the American Geriatrics Society, 55, pp. 700-707. (doi: 10.1111/j.1532-5415.2007.01158.x)

Fowkes, F., Lee, A., Lowe, G., Murray, G., Rumley, A. and Tzoulaki, I. (2007) Inflammatory, haemostatic, and rheological markers for incident peripheral arterial disease: Edinburgh Artery Study. European Heart Journal, 28, pp. 354-362. (doi: 10.1093/eurheartj/ehl441)

Fowkes, F., Lee, A., Lowe, G., Murray, G., Rumley, A. and Tzoulaki, I. (2007) Relative value of inflammatory, hemostatic, and rheological factors for incident myocardial infarction and stroke - The Edinburgh Artery Study. Circulation, 115, pp. 2119-2127. (doi: 10.1161/CIRCULATIONAHA.106.635029)

Gimeno, D., Brunner, E., Lowe, G., Rumley, A., Marmot, M. and Ferrie, J. (2007) Adult socioeconomic position, C-reactive protein and interleukin-6 in the Whitehall II prospective study. European Journal of Epidemiology, 22, pp. 675-683. (doi: 10.1007/s10654-007-9171-9)

Heikkila, K., Ebrahim, S., Rumley, A., Lowe, G. and Lawlor, D.A. (2007) Associations of circulating C-reactive protein and interleukin-6 with survival in women with and without cancer: Findings from the British Women's Heart and Health Study. Cancer Epidemiology, Biomarkers and Prevention, 16, pp. 1155-1159. (doi: 10.1158/9965.EPI-07-0093)

Humphries, S., Hurel, S., Lowe, G., Rumley, A. and Stephens, J. (2007) Association between plasma IL-6, the IL6-174G > C gene variant and the metabolic syndrome in type 2 diabetes mellitus. Molecular Genetics and Metabolism, 90(4), pp. 422-428.

Kaptoge, S., White, I., Thompson, S., Wood, A., Lewington, S., Lowe, G. and Danesh, J. (2007) Associations of plasma fibrinogen levels with established cardiovascular disease risk factors, inflammatory markers, and other characteristics: Individual participant meta-analysis of 154,211 adults in 31 prospective studies. American Journal of Epidemiology, 166, pp. 867-879. (doi: 10.1093/aje/kwm191)

Kelly, A., Lowe, G., Rumley, A., Sattar, N. , Tchernova, J., Wallace, A., Wannamethee, S. and Whincup, P. (2007) Plasma leptin: Associations with metabolic, inflammatory and haemostatic risk factors for cardiovascular disease. Atherosclerosis, 191, pp. 418-426. (doi: 10.1016/j.atherosclerosis.2006.04.012)

Lowe, G. (2007) Inflammatory/hemostatic biomarkers and cardiovascular risk: coming of age? Journal of Thrombosis and Haemostasis, 5(6), pp. 1125-1127.

Lowe, G. (2007) Is venous thrombosis a risk factor for arterial thrombosis? Lancet, 370(9601), pp. 1742-1744.

Lowe, G. (2007) Update on the cardiovascular risks of hormone replacement therapy. Women's Health, 3, pp. 87-97.

Lowe, G., Rudnicka, A., Rumley, A. and Strachan, D. (2007) Diurnal, seasonal, and blood-processing patterns in levels of circulating fibrinogen, fibrin D-dimer, C-reactive protein, tissue plasminogen activator, and von Willebrand factor in a 45-year-old population. Circulation, 115, pp. 996-1003. (doi: 10.1161/CIRCULATIONAHA.106.635169)

Lowe, G., Rumley, A., Wannamethee, S. and Whincup, P. (2007) Inter-relationships of interleukin-6, cardiovascular risk factors and the metabolic syndrome among older men. Journal of Thrombosis and Haemostasis, 5, pp. 1637-1643.

Power, C. et al. (2007) Life-course influences on health in British adults: effects of socio-economic position in childhood and adulthood. International Journal of Epidemiology, 36, pp. 532-539. (doi: 10.1093/ije/dy131O)

Sattar, N. , Crompton, P., Cherry, L., Kane, D., Lowe, G. and McInnes, I. (2007) Effects of tumor necrosis factor blockade on cardiovascular risk factors in psoriatic arthritis: a double-blind, placebo-controlled study. Arthritis and Rheumatism, 56, pp. 831-839. (doi: 10.1002/art.22447) (PMID:17328057)

Stephens, J., Hurel, S., Lowe, G., Rumley, A. and Humphries, S. (2007) Association between plasma IL-6, the IL6-174G > C gene variant and the metabolic syndrome in type 2 diabetes mellitus. Molecular Genetics and Metabolism, 90, pp. 422-428. (doi: 10.1016/j.ymgme.2006.10.004)

Woodward, M., Rumley, A., Welsh, P., Macmahon, S. and Lowe, G. (2007) A comparison of the associations between seven hemostatic or inflammatory variables and coronary heart disease. Journal of Thrombosis and Haemostasis, 5, pp. 1795-1800.

Barber, M., Langhorne, P. , Rumley, A., Lowe, G.D.O. and Stott, D.J. (2006) D-dimer predicts early clinical progression in ischemic stroke: confirmation using routine clinical assays. Stroke, 37(4), pp. 1113-1115. (doi: 10.1161/01.STR.0000209240.63821.1a)

Anandan, C., Fowkes, F., Lee, A., Lowe, G., Powell, J., Rumley, A., Smith, F. and Tzoulaki, I. (2006) Reduced lung function in patients with abdominal aortic aneurysm is associated with activation of inflammation and hemostasis, not smoking or cardiovascular disease. Journal of Vascular Surgery, 43, pp. 474-480. (doi: 10.1016/j.jvs.2005.11.018)

Bruckdorfer, K., Lowe, G., Rumley, A., Wannamethee, S. and Whincup, P. (2006) Associations of vitamin C status, fruit and vegetable intakes, and markers of inflammation and hemostasis. American Journal of Clinical Nutrition, 83, pp. 567-574.

Collins, R., Danesh, J., Higgins, J., Keavney, B., Liu, E., Lowe, G. and Ye, Z. (2006) Seven haemostatic gene polymorphisms in coronary disease: meta-analysis of 66 155 cases and 91 307 controls. Lancet, 367, pp. 651-658.

Emberson, J., Lennon, L., Lowe, G., Rumley, A., Wannamethee, S. and Whincup, P. (2006) Effects of older age on fibrin D-dimer, C-reactive protein, and other hemostatic and inflammatory variables in men aged 60-79 years. Journal of Thrombosis and Haemostasis, 4, pp. 982-987.

Fowkes, F., Lee, A., Lowe, G., Murray, G., Price, J., Rumley, A., Smith, F. and Tzoulaki, I. (2006) Hemostatic factors, inflammatory markers, and progressive peripheral atherosclerosis - The Edinburgh Artery Study. American Journal of Epidemiology, 163, pp. 334-341. (doi: 10.1093/aje/kwj051)

Lennon, L., Lowe, G., Rumley, A., Shaper, A., Wannamethee, S. and Whincup, P. (2006) Renal function and cardiovascular mortality in elderly men: the role of inflammatory, procoagulant, and endothelial biomarkers. European Heart Journal, 27, pp. 2975-2981. (doi: 10.1093/eurheartj/ehl402)

Lowe, G. (2006) Arterial disease and venous thrombosis: are they related, and if so, what should we do about it? Journal of Thrombosis and Haemostasis, 4(9), pp. 1882-1885.

Lowe, G. (2006) The association between elevated levels of inflammation biomarkers and coronary artery disease and death. Canadian Medical Association Journal, 174(4), pp. 479-480.

Lowe, G. (2006) Can haematological tests predict cardiovascular risk? The 2005 Kettle Lecture. British Journal of Haematology, 133(3), pp. 232-250.

Lowe, G. (2006) Local inflammation, endothelial dysfunction and fibrinolysis in coronary heart disease. Clinical Science, 110(3), pp. 327-328.

Lowe, G. and Pepys, M. (2006) C-reactive protein and cardiovascular disease: Weighing the evidence. Current Atherosclerosis Reports, 8(5), pp. 421-428. (doi: 10.1007/s11883-006-0040-x)

Lowe, G. and Sattar, N. (2006) High sensitivity C-reactive protein and cardiovascular disease: an association built on unstable foundations? Annals of Clinical Biochemistry, 43, pp. 252-256.

Will, M., Bernacca, G., Bell, E., Tolland, M., Lowe, G., Rumley, A., Murray, H., Ford, I. and Wheatley, D. (2006) Our inability to predict thromboembolic events after prosthetic valve surgery. Journal of Heart Valve Disease, 15(4), pp. 570-580.

Woodward, M., Rumley, A., Rumley, A., Rumley, C., Lewington, S., Morrison, C. and Lowe, G. (2006) The association between homocysteine and myocardial infarction is independent of age, sex, blood pressure, cholesterol, smoking and markers of inflammation: the Glasgow Myocardial Infarction Study. Blood Coagulation and Fibrinolysis, 17, pp. 1-5.

Wu, O. et al. (2006) Screening for thrombophilia in high-risk situations: systematic review and cost-effectiveness analysis. The Thrombosis: Risk and Economic Assessment of Thrombophilia Screening (TREATS) study. Health Technology Assessment, 10, 1-+.

Stott, D. J. et al. (2005) Randomized controlled trial of homocysteine-lowering vitamin treatment in elderly patients with vascular disease. American Journal of Clinical Nutrition, 82(6), pp. 1320-1326. (doi: 10.1093/ajcn/82.6.1320) (PMID:16332666)

Murdoch, D.L., O'Neill, K., Jackson, J., McMahon, A. , Rumley, A., Wallace, I., Lowe, G.D.O. and Tait, R.C. (2005) Are atrial fibrillation guidelines altering management? A community based study. Scottish Medical Journal, 50(4), pp. 166-169. (doi: 10.1177/003693300505000409) (PMID:16374981)

Danesh, J., Lewington, S., Thompson, S.G., Lowe, G.D.O. and Collins, R. (2005) Plasma fibrinogen level and the risk of major cardiovascular diseases and nonvascular mortality: an individual participant meta-analysis. JAMA: Journal of the American Medical Association, 294(14), pp. 1799-1809. (doi: 10.1001/jama.294.14.1799)

Barber, M., Lowe, G., Rumley, A., Scott, J., Stott, D. and Tait, R. (2005) Dementia in subjects with atrial fibrillation; haemostatic function and the role of anticoagulation (vol 33, pg 10, 2004). Age and Ageing, 34,

Belo, L., Santos-Silva, A., Lowe, G., Rumley, A., Quintanilha, A. and Rebelo, I. (2005) High-density lipoprotein particles may regulate hemostasis in human pregnancy. Fertility and Sterility, 84(4), pp. 1021-1022.

Cherry, L., Divecha, H., Lowe, G., Rumley, A., Sattar, N. and Sturrock, R. (2005) Cardiovascular risk parameters in men with ankylosing spondylitis in comparison with non-inflammatory control subjects: relevance of systemic inflammation. Clinical Science, 109(2), pp. 171-176.

Davey Smith, G., Lawlor, D.A., Harbord, R., Timpson, N., Rumley, A., Lowe, G.D.O., Day, I.N.M. and Ebrahim, S. (2005) Association of C-reactive protein with blood pressure and hypertension - Life course confounding and Mendelian randomization tests of causality. Arteriosclerosis, Thrombosis, and Vascular Biology, 25(5), pp. 1051-1056. (doi: 10.1161/01.ATV.0000160351.95181.d0)

Day, I.N.M., Ebrahim, S., Harbord, R., Lawlor, D.A., Lowe, G.D., Rumley, A., Smith, G.D. and Timpson, N. (2005) Association of C-reactive protein with blood pressure - Response. Arteriosclerosis, Thrombosis, and Vascular Biology, 25(9), E137-E138.

Fowkes, F., Lee, A., Lowe, G., Murray, G., Rumley, A. and Tzoulaki, I. (2005) C-reactive protein, interleukin-6, and soluble adhesion molecules as predictors of progressive peripheral atherosclerosis in the general population - Edinburgh Artery Study. Circulation, 112, pp. 976-983. (doi: 10.1161/CIRCULATIONHA.104.513085)

Kumari, M., Marmot, M., Rumley, A. and Lowe, G. (2005) Social, behavioral, and metabolic determinants of plasma viscosity in the Whitehall II Study. Annals of Epidemiology, 15, pp. 398-404. (doi: 10.1016/j.annepidem.2005.01.004)

Lawlor, D., Davey Smith, G., Rumley, A., Lowe, G. and Ebrahim, S. (2005) Associations of fibrinogen and C-reactive protein with prevalent and incident coronary heart disease are attenuated by adjustment for confounding factors - British Women's Heart and Health Study. Thrombosis and Haemostasis, 93(5), pp. 955-963. (doi: 10.1160/TH04-12-0805)

Lennon, L., Lowe, G., Rumley, A., Shaper, A., Wannamethee, S. and Whincup, P. (2005) Associations between cigarette smoking, pipe/cigar smoking, and smoking cessation, and haemostatic and inflammatory markers for cardiovascular disease. European Heart Journal, 26, pp. 1765-1773. (doi: 10.1093/eurheartj/ehi183)

Lennon, L., Lowe, G., Rumley, A., Shaper, A., Wannamethee, S. and Whincup, P. (2005) The metabolic syndrome and insulin resistance: relationship to haemostatic and inflammatory markers in older non-diabetic men. Atherosclerosis, 181, pp. 101-108. (doi: 10.1016/j.atherosclerosis.2004.12.031)

Lowe, G. (2005) Diagnosis and management of intermittent claudication. Prescriber, 2005, pp. 36-44.

Lowe, G.D.O. (2005) Circulating inflammatory markers and risks of cardiovascular and non-cardiovascular disease. Journal of Thrombosis and Haemostasis, 3(8), pp. 1618-1627. (doi: 10.1111/j.1538-7836.2005.01416.x)

Lowe, G.D.O. (2005) Fibrinogen measurement to assess the risk of arterial thrombosis in individual patients: not yet. Journal of Thrombosis and Haemostasis, 3(4), pp. 635-637. (doi: 10.1111/j.1538-7836.2005.01256.x)

Lowe, G.D.O. and Danesh, J. (2005) Classical and emerging risk factors for cardiovascular disease. Seminars in Vascular Medicine, 02(03), pp. 229-445.

Lowe, G.D.O., Rumley, A. and Wannamethee, S.G. (2005) Hemostatic abnormalities associated with obesity and the metabolic syndrome. Journal of Thrombosis and Haemostasis, 3(5), pp. 1076-1078. (doi: 10.1111/j.1538-7836.2005.01301.x)

Lowe, G. (2005) Fibrin D-Dimer and Cardiovascular Risk. [Article]. Seminars in Vascular Medicine Fibrin D-dimer Testing For Venous and Arterial Thrombotic Disease, Decemb(4), pp. 387-398.

Robins, J., Woodward, M., Lowe, G., McCaul, P., Cheyne, H. and Walker, J. (2005) First trimester maternal blood rheology and pregnancy induced hypertension. Journal of Obstetrics and Gynaecology, 25(8), pp. 746-750. (doi: 10.1080/01443610500314637)

Smith, A., Patterson, C., Yarnell, J., Rumley, A., Ben Shlomo, Y. and Lowe, G. (2005) Which hemostatic markers add to the predictive value of conventional risk factors for coronary heart disease and ischemic stroke? The Caerphilly Study. Circulation, 112, pp. 3080-3087. (doi: 10.1161/CIRCULATIONAHA.105.557132)

Timpson, N. et al. (2005) C-reactive protein and its role in metabolic syndrome: mendelian randomisation study. Lancet, 366(9501), pp. 1954-1959. (doi: 10.1016/S0140-6736(05)67786-0)

Woodward, M. et al. (2005) Associations of inflammatory and hemostatic variables with the risk of recurrent stroke. Stroke, 36(10), pp. 2143-2147. (doi: 10.1161/01.STR.0000181754.38408.4c)

Wu, O. et al. (2005) Oral contraceptives, hormone replacement therapy, thrombophilias and risk of venous thromboembolism: a systematic review. Thrombosis and Haemostasis, 94, pp. 17-25.

Wu, O. et al. (2005) Screening for thrombophilia in high-risk situations: a meta-analysis and cost-effectiveness analysis. British Journal of Haematology, 131, pp. 80-90. (doi: 10.1111/j.1365-2141.2005.05715.x)

Wu, O. , Clark, P., Lowe, G.D.O., Walker, I.D. and Greer, I.A. (2005) Thrombophilia and venous thromboembolism after total hip or knee replacement surgery: a systematic review. Journal of Thrombosis and Haemostasis, 3(4), pp. 811-813. (doi: 10.1111/j.1538-7836.2005.01264.x)

Wu, O. et al. (2005) Oral contraceptives, hormone replacement therapy, thrombophilias and risk of venous thromboembolism: a systematic review The Thrombosis: Risk and Economic Assessment of Thrombophilia Screening (TREATS) Study. Thrombosis and Haemostasis, 94(1), pp. 17-25. (doi: 10.1160/TH04-11-0759)

Yarnell, J., McCrum, E., Rumley, A., Patterson, C., Salomaa, V., Lowe, G. and Evans, A. (2005) Association of European population levels of thrombotic and inflammatory factors with risk of coronary heart disease: the MONICA Optional Haemostasis Study. European Heart Journal, 26, pp. 332-342. (doi: 10.1093/eurhreartj/ehi052)

Barber, M., Tait, R.C. , Scott, J., Rumley, A., Lowe, G. and Stott, D.J. (2004) Dementia in subjects with atrial fibrillation: hemostatic function and the role of anticoagulation. Journal of Thrombosis and Haemostasis, 2(11), pp. 1873-1878. (doi: 10.1111/j.1538-7836.2004.00993.x) (PMID:15550013)

Lowe, G.D.O. (2004) Azithromycin does not reduce recurrent coronary events. Evidence-Based Healthcare, 8(2), pp. 105-106. (doi: 10.1016/j.ehbc.2004.02.019)

Lowe, G.D.O. (2004) Venous and arterial thrombosis: epidemiology and risk factors at various ages. Maturitas, 47(4), pp. 259-263. (doi: 10.1016/j.maturitas.2003.12.009)

Bainton, D., Ben, S.Y., Lowe, G.D.O., Rumley, A., Rumley, C., Sweetnam, P.M. and Yarnell, J.W.G. (2004) C-reactive protein, fibrin D-dimer, and risk of ischemic heart disease - The Caerphilly and Speedwell studies. Arteriosclerosis, Thrombosis, and Vascular Biology, 24, pp. 1957-1962. (doi: 10.1161/01.ATV.0000141842.27810.a9)

Barber, M., Langhorne, P. , Rumley, A., Lowe, G.D.O. and Stott, D.J. (2004) Hemostatic function and progressing ischemic stroke: D-dimer predicts early clinical progression. Stroke, 35(6), pp. 1421-1425. (doi: 10.1161/01.STR.0000126890.63512.41)

Campbell, S.E., Walker, A.E., Grimshaw, J.M., Campbell, M.K., Lowe, G.D.O., Harper, D., Fowkes, F.G.R. and Petrie, J.C. a. T. g. (2004) The prevalence of prophylaxis for deep vein thrombosis in acute hospital trusts. International Journal for Quality in Health Care, 13(4), pp. 309-316. (doi: 10.1093/intqhc/13.4.309)

Danesh, J., Wheeler, J.G., Hirschfield, G.M., Eda, S., Eiriksdottir, G., Rumley, A., Lowe, G.D.O., Pepys, M.B. and Gudnason, V. (2004) C-reactive protein and other circulating markers of inflammation in the prediction of coronary heart disease. New England Journal of Medicine, 350(14), pp. 1387-1397.

Emberson, J.R., Whincup, P.H., Morris, R.W., Walker, M., Lowe, G.D.O. and Rumley, A. (2004) Extent of regression dilution for established and novel coronary risk factors: Results from the British Regional Heart Study. European Journal of Cardiovascular Prevention and Rehabilitation, 11(2), pp. 125-134. (doi: 10.1097/01.hjr.0000114967.39211.e5)

Ford, I. , Lowe, G.D.O., McMahon, A.D. , O'Reilly, D.S., Packard, C.J. and Rumley, A. (2004) Interleukin-6, fibrin D-dimer, and coagulation factors VII and XIIa in prediction of coronary heart disease. Arteriosclerosis, Thrombosis, and Vascular Biology, 24, pp. 1529-1534. (doi: 10.1161/01.ATV.0000135995.39488.6c)

Fox, K., Gallimore, J., Gomma, A., Hirschfield, G., Lowe, G. and Pepys, M. (2004) Preprocedural inflammatory markers do not predict restenosis after successful coronary stenting. American Heart Journal, 147, pp. 1071-1077. (doi: 10.1016/j.ahj.2003.10.050)

Kostis, J.B. et al. (2004) Collaborative meta-analysis of prospective studies of plasma fibrinogen and cardiovascular disease. European Journal of Cardiovascular Prevention and Rehabilitation, 11(1), pp. 9-17.

Lowe, G., Danesh, J., Lewington, S., Walker, M., Lennon, L., Thomson, A., Rumley, A. and Whincup, P.H. (2004) Tissue plasminogen activator antigen and coronary heart disease. European Heart Journal, 25(3), pp. 252-259. (doi: 10.1016/j.ehj.2003.11.004)

Lowe, G.D.O. (2004) Dental disease, coronary heart disease and stroke, and inflammatory markers - What are the associations, and what do they mean? Circulation, 109(9), pp. 1076-1078. (doi: 10.1161/01.CIR.0000118643.41559.E2)

Lowe, G.D.O., Rumley, A. and Mackie, I.J. (2004) Plasma fibrinogen. Annals of Clinical Biochemistry, 41(6), pp. 430-440. (doi: 10.1258/0004563042466884)

Lowe, G.D.O., Rumley, A., Rumley, A.G., Rumley, J. and Woodward, M. (2004) Plasma lipid peroxides: relationships to cardiovascular risk factors and prevalent cardiovascular disease. QJM: An International Journal of Medicine, 97, pp. 809-816. (doi: 10.1093/qjmed/hch130)

Lowe, G. (2004) Hormone replacement therapy and cardiovascular disease: increased risks of venous thromboembolism and stroke, and no protection from coronary heart disease. Journal of Internal Medicine, 256, pp. 361-374.

Lowe, G., MacCallum, P., Meade, T., Rudnicka, A. and Rumley, A. (2004) Low-intensity warfarin reduces thrombin generation and fibrin turnover, but not low-grade inflammation, in men at risk of myocardial infarction. British Journal of Haematology, 127, pp. 448-450. (doi: 10.1111/j.1365-2141.2004.05222.x)

Lowe, G., Patterson, C., Sweetnam, P. and Yarnell, J. (2004) Haemostatic/inflammatory markers predict 10-year risk of IHD at least as well as lipids: the Caerphilly collaborative studies. European Heart Journal, 25, pp. 1049-1056. (doi: 10.1016/j.ehj.2004.04.011)

MacCallum, P.K., Cooper, J.A., Rumley, A., Lowe, G.D.O. and Meade, T.W. (2004) Effect of bezafibrate on plasma homocysteine concentration in men with lower extremity arterial disease. Journal of Thrombosis and Haemostasis, 2(2), pp. 364-365. (doi: 10.1111/j.1538-7933.2004.0584l.x)

Wannamethee, S.G., Lowe, G.D.O., Shaper, A.G., Rumley, A., Lennon, L. and Whincup, P.H. (2004) Insulin resistance, haemostatic and inflammatory markers and coronary heart disease risk factors in Type 2 diabetic men with and without coronary heart disease. Diabetologia, 47(9), pp. 1557-1565. (doi: 10.1007/s00125-004-1491-7)

Woodward, M., Lowe, G., Francis, L., Rumley, A. and Cobbe, S. (2004) A randomized comparison of the effects of aspirin and clopidogrel on thrombotic risk factors and C-reactive protein following myocardial infarction: the ADET trial. Journal of Thrombosis and Haemostasis, 2(11), pp. 1934-1940. (doi: 10.1111/j.1538-7836.2004.01017.x)

Yu, S.C., Lowe, G.D.O., Yarnell, J.W.G. and Sweetnam, P.M. (2004) Resonance-thrombography indices of the haemostatic process in relation to risk of incident coronary heart disease: 9 years follow-up in the Caerphilly Prospective Heart Disease Study. British Journal of Haematology, 126(3), pp. 385-391. (doi: 10.1111/j.1365-2141.2004.05054.x)

Brull, D.J. et al. (2003) Human CRP gene polymorphism influences CRP levels - implications for the prediction and pathogenesis of coronary heart disease. Arteriosclerosis, Thrombosis, and Vascular Biology, 23(11), pp. 2063-2069. (doi: 10.1161/01.ATV.0000084640.21712.9C)

Forouhi, N.G., Rumley, A., Lowe, G.D., McKeigue, P. and Sattar, N. (2003) Specific elevation in plasma tissue plasminogen activator antigen concentrations in South Asians relative to Europeans. Blood Coagulation and Fibrinolysis, 14(8), pp. 755-760.

Imhof, A., Frohlich, M., Loewel, H., Helbecque, N., Woodward, M., Amouyel, P., Lowe, G.D.O. and Koenig, W. (2003) Distributions of C-reactive protein measured by high- sensitivity assays in apparently healthy men and women from different populations in Europe. Clinical Chemistry, 49(4), pp. 669-672. (doi: 10.1373/49.4.669)

Jespersen, J., Lowe, G., Samsioe, G., Skouby, S. and Stevenson, J. (2003) The European Consensus Development Conference 2002: Sex Steroids and Cardiovascular Diseases - On the route to combined evidence from OC and HRT/ERT. Maturitas, 44, pp. 69-82. (doi: 10.1016/S0378-5122(02)00351-1)

Lowe, G.D.O., Sandercock, P.A.G. and Rosendaal, F.R. (2003) Prevention of venous thromboembolism after major orthopaedic surgery: is fondaparinux an advance? Lancet, 362(9383), pp. 504-505. (doi: 10.1016/S0140-6736(03)14149-9)

Lowe, G.D.O., Woodward, M., Rumley, A., Morrison, C. and Nieuwenhuizen, W. (2003) Associations of plasma fibrinogen assays, C-reactive protein and interleukin-6 with previous myocardial infarction. Journal of Thrombosis and Haemostasis, 1(11), pp. 2312-2316. (doi: 10.1046/j.1538-7836.2003.00467.x)

Lowe, G./, Woodward, M., Rumley, A./, Morrison, C., Tunstall-Pedoe, H. and Stephen, K. (2003) Total tooth loss and prevalent cardiovascular disease in men and women - Possible roles of citrus fruit consumption, vitamin C, and inflammatory and thrombotic variables. Journal of Clinical Epidemiology, 56(7), pp. 694-700. (doi: 10.1016/S0895-4356(03)00086-6)

Lowe, G. (2003) Clopidogrel in prevention of cardiovascular events. Reviews in Contemporary Pharmacology, 12, pp. 265-298.

Lowe, G., Rosendaal, F. and Sandercock, P. (2003) Fondaparinux and prevention of venous thromboembolism after orthopaedic surgery - Reply. Lancet, 362(9395), p. 1582.

Lowe, G. (2003) Different locations of atherosclerosis - Different risk factors, different therapies? Pathophysiology of Haemostasis and Thrombosis, 33, pp. 262-266.

Lowe, G. (2003) Virchow's triad revisited: Abnormal flow. Pathophysiology of Haemostasis and Thrombosis, 33, pp. 455-457.

Mackie, I.J., Kitchen, S., Machin, S.J. and Lowe, G.D.O. (2003) Guidelines on fibrinogen assays. British Journal of Haematology, 121(3), pp. 396-404. (doi: 10.1046/j.1365-2141.2003.04256.x)

Maclean, P.S., Tait, R.C. , Lowe, G.D.O., Walker, I.D. and McColl, M.D. (2003) Successful elimination of factor VIII inhibitor using cyclosporin A. British Journal of Haematology, 122(6), pp. 1024-1025. (doi: 10.1046/j.1365-2141.2003.04519.x)

Maclean, P.S., Tait, R.C., Rumley, A., McMahon, A. and Lowe, G.D. (2003) Anticoagulation with warfarin downregulates inflammation. Journal of Thrombosis and Haemostasis, 1(8), pp. 1838-1839. (doi: 10.1046/j.1538-7836.2003.t01-1-00372.x)

McKenzie, J. et al. (2003) Metabolic, inflammatory and haemostatic effects of a low-dose continuous combined HRT in women with type 2 diabetes: potentially safer with respect to vascular risk? Clinical Endocrinology, 59(6), pp. 682-689. (doi: 10.1046/j.1365-2265.2003.01906.x)

Paisley, K.E., Beaman, M., Tooke, J.E., Mohamed-Ali, V., Lowe, G.D.O. and Shore, A.C. (2003) Endothelial dysfunction and inflammation in asymptomatic proteinuria. Kidney International, 63(2), pp. 624-633. (doi: 10.1046/j.1523-1755.2003.00768.x)

Perry, C.G., Spiers, A., Cleland, S.J., Lowe, G.D.O., Petrie, J.R. and Connell, J.M.C. (2003) Glucocorticoids and insulin sensitivity: dissociation of insulin's metabolic and vascular actions. Journal of Clinical Endocrinology and Metabolism, 88(12), pp. 6008-6014. (doi: 10.1210/jc.2002-021605)

Rumley, A., Woodward, M., Hoffmeister, A., Koenig, W. and Lowe, G.D.O. (2003) Comparison of plasma fibrinogen by Clauss, prothrombin time- derived, and immunonephelometric assays in a general population: implications for risk stratification by thirds of fibrinogen. Blood Coagulation and Fibrinolysis, 14(2), pp. 197-201.

Smith, F., Connor, J.M., Lee, A.J., Cooke, A., Lowe, G.D.O., Rumley, A. and Fowkes, F.G. (2003) Relationship of the platelet glycoprotein P1(A) and fibrinogen T/G(+1689) polymorphisms with peripheral arterial disease and ischaemic heart disease. Thrombosis Research, 112(4), pp. 209-216. (doi: 10.1016/j.thromres.2003.11.010)

Stansby, G. et al. (2003) Antiplatelet therapy in peripheral arterial disease. Consensus statement. European Journal of Vascular and Endovascular Surgery, 26(1), pp. 1-16. (doi: 10.1053/ejvs.2002.1927)

Steptoe, A., Kunz-Ebrecht, S., Owen, N., Feldman, P.J., Rumley, A., Lowe, G.D.O. and Marmot, M. (2003) Influence of socioeconomic status and job control on plasma fibrinogen response's to acute mental stress. Psychosomatic Medicine, 65(1), pp. 137-144. (doi: 10.1097/01.PSY.0000039755.23250.A7)

Steptoe, A., Kunz-Ebrecht, S., Rumley, A. and Lowe, G.D.O. (2003) Prolonged elevations in haemostatic and rheological responses following psychological stress in low socioeconomic status men and women. Thrombosis and Haemostasis, 89(1), pp. 83-90.

Wannamethee, S.G., Lowe, G.D.O., Shaper, G., Whincup, P.H., Rumley, A., Walker, M. and Lennon, L. (2003) The effects of different alcoholic drinks on lipids, insulin and haemostatic and inflammatory markers in older men. Thrombosis and Haemostasis, 90(6), pp. 1080-1087.

Woodward, M., Lowe, G., Rumley, A., Imhof, A. and Koenig, W. (2003) Measurement of plasma viscosity in stored frozen samples: a general population study. Blood Coagulation and Fibrinolysis, 14(4), pp. 417-420.

Woodward, M., Oliphant, J., Lowe, G. and Tunstall-Pedoe, H. (2003) Contribution of contemporaneous risk factors to social inequality in coronary heart disease and all causes mortality. Preventive Medicine, 36(5), pp. 561-568. (doi: 10.1016/S0091-7435(03)00010-0)

Woodward, M., Rumley, A., Lowe, G.D.O. and Tunstall-Pedoe, H. (2003) C-reactive protein: associations with haematological variables, cardiovascular risk factors and prevalent cardiovascular disease. British Journal of Haematology, 122(1), pp. 135-141. (doi: 10.1046/j.1365-2141.2003.04387.x)

Woodward, M., Rumley, A., Tunstall-Pedoe, H. and Lowe, G.D.O. (2003) Does sticky blood predict a sticky end? Associations of blood viscosity, haematocrit and fibrinogen with mortality in the West of Scotland. British Journal of Haematology, 122(4), pp. 645-650. (doi: 10.1046/j.1365-2141.2003.04475.x)

Dykes, A.C., Walker, I.D., Lowe, G.D.O. and Tait, R.C. (2002) Treatment of acquired haemophilia. Internal Medicine Journal, 32(12), 625-6U4. (doi: 10.1046/j.1445-5994.2002.00303.x) (PMID:12512761)

Wannamethee, S.G., Lowe, G.D.O., Whincup, P.H., Rumley, A., Walker, M. and Lennon, L. (2002) Physical activity and hemostatic and inflammatory variables in elderly men. Circulation, 105(15), pp. 1785-1790.

Basso, F., Lowe, G.D.O., Rumley, A., McMahon, A.D. and Humphries, S.E. (2002) Interleukin-6 -174G > C polymorphism and risk of coronary heart disease in West of Scotland Coronary Prevention Study (WOSCOPS). Arteriosclerosis, Thrombosis, and Vascular Biology, 22(4), pp. 599-604. (doi: 10.1161/01.ATV.0000013283.84306.1A)

Belo, L., Santos-Silva, A., Rumley, A., Lowe, G., Pereira-Leite, L., Quintanilha, A. and Rebelo, I. (2002) Elevated tissue plasminogen activator as a potential marker of endothelial dysfunction in pre-eclampsia: correlation with proteinuria. BJOG: An International Journal of Obstetrics and Gynaecology, 109(11), pp. 1250-1255. (doi: 10.1016/S1470-0328(02)01957-2)

Bergqvist, D. and Lowe, G. (2002) Venous thromboembolism in patients undergoing laparoscopic and arthroscopic surgery and in leg casts. Archives of Internal Medicine, 162(19), pp. 2173-2176.

Brull, D.J., Dhamrait, S., Moulding, R., Rumley, A., Lowe, G.D.O., World, M.J., Humphries, S.E. and Montgomery, H.E. (2002) The effect of fibrinogen genotype on fibrinogen levels after strenuous physical exercise. Thrombosis and Haemostasis, 87(1), pp. 37-41.

Brull, D.J., Sanders, J., Rumley, A., Lowe, G.D., Humphries, S.E. and Montgomery, H.E. (2002) Impact of angiotensin converting enzyme inhibition on post- coronary artery bypass interleukin 6 release. Heart, 87(3), pp. 252-255.

Brunner, E. et al. (2002) Adrenocortical, autonomic, and inflammatory causes of the metabolic syndrome - nested case-control study. Circulation, 106(21), pp. 2659-2665. (doi: 10.1161/01.CIR.0000038364.26310.BD)

Freeman, D.J. , Norrie, J., Caslake, M.J., Gaw, A., Ford, I. , Lowe, G.D.O., O'Reilly, D. S. J.,, Packard, C.J. and Sattar, N. (2002) C-reactive protein is an independent predictor of risk for the development of diabetes in the West of Scotland Coronary Prevention Study. Diabetes, 51(5), pp. 1596-1600. (doi: 10.2337/diabetes.51.5.1596)

Freeman, D.J. , Norrie, J., Caslake, M.J., Gaw, A., Ford, I. , Lowe, G.D.O., O'Reilly, D.S., Packard, C.J. and Sattar, N. (2002) C-reactive protein is an independent predictor of risk for the development of diabetes in the West of Scotland Coronary Prevention Study. Diabetes, 51(5), pp. 1596-1600.

Hankey, C.R., Lean, M.E.J. , Lowe, G.D.O., Rumley, A. and Woodward, M. (2002) Effects of moderate weight loss on anginal symptoms and indices of coagulation and fibrinolysis in overweight patients with angina pectoris. European Journal of Clinical Nutrition, 56(10), pp. 1039-1045.

Kelly, C.J.G., Lyall, H., Petrie, J.R. , Gould, G.W. , Connell, J.M.C., Rumley, A., Lowe, G.D.O. and Sattar, N. (2002) A specific elevation in tissue plasminogen activator antigen in women with polycystic ovarian syndrome. Journal of Clinical Endocrinology and Metabolism, 87(7), pp. 3287-3290. (doi: 10.1210/jc.87.7.3287)

Lowe, G.D.O. (2002) Hormone replacement therapy: prothrombotic vs. protective effects. Pathophysiology of Haemostasis and Thrombosis, 32(5-6), pp. 329-332. (doi: 10.1159/000073592)

Lowe, G.D.O. (2002) Measurement of thrombosis and its prevention. British Journal of Clinical Pharmacology, 54(1), pp. 96-100. (doi: 10.1046/j.1365-2125.2002.01626.x)

Lowe, G.D.O. (2002) Which patients with diabetes should receive which antiplatelet agents? British Journal of Diabetes and Vascular Disease, 2002(2), pp. 157-160. (doi: 10.1177/14746514020020030201)

Lowe, G.D.O., Rumley, A., Whincup, P.H. and Danesh, J. (2002) Hemostatic and rheological variables and risk of cardiovascular disease. Seminars in Vascular Medicine, 2002(2), pp. 429-440. (doi: 10.1055/s-2002-36771)

Lowe, G. and Danesh, J. (2002) Classical and Emerging Risk Factors for Cardiovascular Disease. [Miscellaneous]. Seminars in Vascular Medicine, 2(3), p. 229.

Lowe, G., Rumley, A., Whincup, P. and Danesh, J. (2002) Hemostatic and Rheological Variables and Risk of Cardiovascular Disease. [Article]. Seminars in Vascular Medicine Classical and Emerging Risk Factors For Cardiovascular Disease, Part 2, 2002;2(4), pp. 429-440.

Mackie, I.J., Lawrie, A.S., Kitchen, S., Gaffney, P.J., Howarth, D., Lowe, G.D.O., Martin, J., Purdy, G., Rigsby, P. and Rumley, A. (2002) A performance evaluation of commercial fibrinogen reference preparations and assays for Clauss and PT-derived fibrinogen. Thrombosis and Haemostasis, 87(6), pp. 997-1005.

Rosendaal, F.R., Vessey, M., Rumley, A., Daly, E., Woodward, M., Helmerhorst, F.M. and Lowe, G.D. (2002) Hormonal replacement therapy, prothrombotic mutations and the risk of venous thrombosis. British Journal of Haematology, 116(4), pp. 851-854. (doi: 10.1046/j.0007-1048.2002.03356.x)

Whincup, R.H., Danesh, J., Walker, M., Lennon, L., Thomson, A., Appleby, R., Rumley, A. and Lowe, G.D.O. (2002) von Willebrand factor and coronary heart disease - prospective study and meta-analysis. European Heart Journal, 23(22), pp. 1764-1770. (doi: 10.1053/euhj.2001.3237)

Zito, F., Lowe, G.D.O., Rumley, A., McMahon, A.D. and Humphries, S.E. (2002) Association of the factor XII 46C > T polymorphism with risk of coronary heart disease (CHD) in the WOSCOPS study. Atherosclerosis, 165(1), pp. 153-158. (doi: 10.1016/S0021-9150(02)00196-X)

Lowe, G.D.O., Upton, M.N., Rumley, A., McConnachie, A. , O'Reilly, D.S. and Watt, G.C.M. (2001) Different effects of oral and transdermal hormone replacement therapies on Factor IX, APC resistance, t-PA, PAI and C- reactive protein - a cross-sectional population survey. Thrombosis and Haemostasis, 86(2), pp. 550-556.

Brull, D.J., Montgomery, H.E., Sanders, J., Dhamrait, S., Luong, L., Rumley, A., Lowe, G.D.O. and Humphries, S.E. (2001) Interleukin-6 gene -174G gt C and -572G gt C promoter polymorphisms are strong predictors of plasma - Interleukin-6 levels after coronary artery bypass surgery. Arteriosclerosis, Thrombosis, and Vascular Biology, 21(9), pp. 1458-1463.

Brull, D.J., Sanders, J., Rumley, A., Lowe, G.D.O., Humphries, S.E. and Montgomery, H.E. (2001) Statin therapy and the acute inflammatory response after coronary artery bypass grafting. American Journal of Cardiology, 88(4), pp. 431-433. (doi: 10.1016/S0002-9149(01)01696-4)

Danesh, J., Whincup, P., Walker, M., Lennon, L., Thomson, A., Appleby, P., Rumley, A. and Lowe, G.D.O. (2001) Fibrin D-dimer and coronary heart disease - prospective study and meta-analysis. Circulation, 103(19), pp. 2323-2327.

Davie, A.P., Rumley, A., Lowe, G.D.O. and McMurray, J.J.V. (2001) Effect of chronic angiotensin II type I receptor antagonism and angiotensin converting enzyme inhibition on plasma fibrinolytic variables in patients with heart failure. Thrombosis and Haemostasis, 86(6), pp. 1585-1586. (PMID:11776334)

Dykes, A.C., Walker, I.D., Lowe, G.D.O. and Tait, R.C. (2001) Combined prednisolone and intravenous immunoglobulin treatment for acquired factor VIII inhibitors: a 2-year review. Haemophilia, 7(2), pp. 160-163. (doi: 10.1046/j.1365-2516.2001.00489.x)

Lee, B.C., Shore, A.C., Humphreys, J.M., Lowe, G.D., Rumley, A., Clark, P.M., Hattersley, A.T. and Tooke, J.E. (2001) Skin microvascular vasodilatory capacity in offspring of two parents with Type 2 diabetes. Diabetic Medicine, 18(7), pp. 541-545. (doi: 10.1046/j.1464-5491.2001.00514.x)

Lowe, G.D.O. (2001) Factor IX and thrombosis. British Journal of Haematology, 115(3), pp. 507-513. (doi: 10.1046/j.1365-2141.2001.03186.x)

Lowe, G.D.O. (2001) Is sticky blood a treatable determinant of cognitive decline and of dementia? Age and Ageing, 30(2), pp. 101-103.

Lowe, G.D.O. (2001) Who should take aspirin for primary prophylaxis of coronary heart disease? Heart, 85(3), pp. 245-246. (doi: 10.1136/heart.85.3.245)

Lowe, G.D.O. (2001) Why do smokers have higher plasma fibrinogen levels than non- smokers? Clinical Science, 101(2), pp. 209-210.

Lowe, G.D.O. and Rumley, A. (2001) Fibrinogen and its degradation products as thrombotic risk factors. Annals of the New York Academy of Sciences, 936, pp. 560-565.

Lowe, G.D.O., Rumley, A., Sweetnam, P.M., Yarnell, J.W.G. and Rumley, J. (2001) Fibrin D-dimer, markers of coagulation activation and the risk of major ischaemic heart disease in the Caerphilly Study. Thrombosis and Haemostasis, 86(3), pp. 822-827.

Lowe, G.D.O., Yarnell, J.W.G., Rumley, A., Bainton, D. and Sweetnam, P.M. (2001) C-Reactive protein, fibrin D-dimer, and incident ischemic heart disease in the speedwell study - Are inflammation and fibrin turnover linked in pathogenesis? Arteriosclerosis, Thrombosis, and Vascular Biology, 21(4), pp. 603-610.

Lowe, G. (2001) Ancrod in treatment of acute ischaemic stroke. Proceedings of the Royal College of Physicians of Edinburgh, 31(Suppl.), pp. 20-24.

Lowe, G. (2001) Scottish physicians' clinical standards and audit colaboration. Proceedings of the Royal College of Physicians of Edinburgh, 31, p. 252.

Lowe, G. (2001) Why do smokers have higher plasma fibrinogen levels than non-smokers? Clinical Science, 101(2), pp. 209-210.

Mamode, N., Docherty, G., Lowe, G.D.O., Macfarlane, P.W., Martin, W., Pollock, J.G. and Cobbe, S.M. (2001) The role of myocardial perfusion scanning, heart rate variability and D-dimers in predicting the risk of perioperative cardiac complications after peripheral vascular surgery. European Journal of Vascular and Endovascular Surgery, 22(6), pp. 499-508. (doi: 10.1053/ejvs.2001.1529)

McEntegart, A., Capell, H.A., Creran, D., Rumley, A., Woodward, M. and Lowe, G.D.O. (2001) Cardiovascular risk factors, including thrombotic variables, in a population with rheumatoid arthritis. Rheumatology, 40(6), pp. 640-644. (doi: 10.1093/rheumatology/40.6.640)

Perera, M., Sattar, N. , Petrie, J.R. , Hillier, C., Small, M., Connell, J.M.C., Lowe, G.D.O. and Lumsden, M.A. (2001) The effects of transdermal estradiol in combination with oral norethisterone on lipoproteins, coagulation, and endothelial markers in postmenopausal women with type 2 diabetes: a randomized, placebo-controlled study. Journal of Clinical Endocrinology and Metabolism, 86(3), pp. 1140-1143. (doi: 10.1210/jc.86.3.1140)

Price, J.F., Lee, A.J., Rumley, A., Lowe, G.D.O. and Fowkes, F.G.R. (2001) Lipoprotein (a) and development of intermittent claudication and major cardiovascular events in men and women: the Edinburgh Artery Study. Atherosclerosis, 157(1), pp. 241-249. (doi: 10.1016/S0021-9150(00)00719-X)

Stonier, P. and Lowe, G. (2001) A national panel for research integrity: a proposed blueprint for the prevention and investigation of misconduct in biomedical research. Proceedings of the Royal College of Physicians of Edinburgh, 31, pp. 253-255.

Stott, D.J. , Spilg, E., Campbell, A.M., Rumley, A., Mansoor, M.A. and Lowe, G.D.O. (2001) Haemostasis in ischaemic stroke and vascular dementia. Blood Coagulation and Fibrinolysis, 12(8), pp. 651-657.

Yarnell, J.W.G., Sweetnam, P.M., Rumley, A. and Lowe, G.D.O. (2001) Lifestyle factors and coagulation activation markers: the Caerphilly Study. Blood Coagulation and Fibrinolysis, 12(8), pp. 721-728.

Danesh, J., Collins, R., Peto, R. and Lowe, G.D.O. (2000) Haematocrit, viscosity, erythrocyte sedimentation rate: meta- analyses of prospective studies of coronary heart disease. European Heart Journal, 21(7), pp. 515-520. (doi: 10.1053/euhj.1999.1699)

Fowkes, F.G.R., Lee, A.J., Hau, C.M., Cooke, A., Connor, J.M. and Lowe, G.D.O. (2000) Methylene tetrahydrofolate reductase (MTHFR) and nitric oxide synthase (ecNOS) genes and risks of peripheral arterial disease and coronary heart disease: Edinburgh artery study. Atherosclerosis, 150(1), pp. 179-185. (doi: 10.1016/S0021-9150(99)00366-4)

Hutchinson, W.L., Koenig, W., Frohlich, M., Sund, M., Lowe, G.D.O. and Pepys, M.B. (2000) Immunoradiometric assay of circulating C-reactive protein: age-related values in the adult general population. Clinical Chemistry, 46(7), pp. 934-938.

Kinane, D.F. and Lowe, G.D.O. (2000) How periodontal disease may contribute to cardiovascular disease. Periodontology 2000, 23, pp. 121-126. (doi: 10.1034/j.1600-0757.2000.2230112.x)

Lamba, N.M.K., Courtney, J.M., Gaylor, J.D.S. and Lowe, G.D.O. (2000) In vitro investigation of the blood response to medical grade PVC and the effect of heparin on the blood response. Biomaterials, 21(1), pp. 89-96. (doi: 10.1016/S0142-9612(99)00145-3)

Lee, A.J., Lowe, G.D.O., Rumley, A., Ruckley, C.V. and Fowkes, F.G.R. (2000) Haemostatic factors and risk of varicose veins and chronic venous insufficiency: Edinburgh vein study. Blood Coagulation and Fibrinolysis, 11(8), pp. 775-781.

Leng, G.C. et al. (2000) Femoral atherosclerosis in an older British population: prevalence and risk factors. Atherosclerosis, 152(1), pp. 167-174. (doi: 10.1016/S0021-9150(99)00447-5)

Lowe, G., Rumley, A., Norrie, J., Ford, I. , Shepherd, J., Cobbe, S., Macfarlane, P. and Packard, C. (2000) Blood rheology, cardiovascular risk factors, and cardiovascular disease: The West of Scotland Coronary Prevention Study. Thrombosis and Haemostasis, 84(4), pp. 553-558.

Lowe, G., Rumley, A., Woodward, M. and Vessey, M. (2000) C-reactive protein, idiopathic venous thromboembolism and hormone replacement therapy. Thrombosis and Haemostasis, 84(4), pp. 730-731.

Lowe, G., Woodward, M., Vessey, M., Rumley, A., Gough, P. and Daly, E. (2000) Thrombotic variables and risk of idiopathic venous thromboembolism in women aged 45-64 years - Relationships to hormone replacement therapy. Thrombosis and Haemostasis, 83(4), pp. 530-535.

Ludlam, C.A., Lee, R.J., Prescott, R.J., Andrews, J., Kirke, E., Thomas, A.E., Chalmers, E. and Lowe, G.D.O. (2000) Haemophilia care in central Scotland 1980-94. I. Demographic characteristics, hospital admissions and causes of death. Haemophilia, 6(5), pp. 494-503. (doi: 10.1046/j.1365-2516.2000.00405.x)

Packard, C.J. et al. (2000) Lipoprotein-associated phospholipase A(2) as an independent predictor of coronary heart disease. New England Journal of Medicine, 343(16), pp. 1148-1155.

Smith, F., Lee, A.J., Hau, C.M., Rumley, A., Lowe, G.D.O. and Fowkes, F.G.R. (2000) Plasma fibrinogen, haemostatic factors and prediction of peripheral arterial disease in the Edinburgh Artery Study. Blood Coagulation and Fibrinolysis, 11(1), pp. 43-50.

Smith, F.B., Fowkes, F.G.R., Rumley, A.,, Lee, A.J., Lowe, G.D.O. and Hau, C.M. (2000) Tissue plasminogen activator and leucocyte elastase as predictors of cardiovascular events in subjects with angina pectoris: Edinburgh Artery Study. European Heart Journal, 21(19), pp. 1607-1613. (doi: 10.1053/euhj.2000.2127)

Yarnell, J.W.G., Sweetnam, P.M., Rumley, A. and Lowe, G.D.O. (2000) Lifestyle and hemostatic risk factors for ischemic heart disease - The Caerphilly Study. Arteriosclerosis, Thrombosis, and Vascular Biology, 20(1), pp. 271-279.

Gilhooly, C. , Mansfield, M.D., Rumley, A., Lowe, G. and Kinsella, J. (1997) Investigation of haemostatic parameters in relation to outcome in an intensive care population. European Journal of Anaesthesiology, 14(5), p. 524.

Collier, A., Rumley, A., Rumley, A. G., Patesron, J. R., Leach, J. P. , Lowe, G. D.O. and Small, M. (1992) Free radical activity and hemostatic factors in NIDDM patients with and without microalbuminuria. Diabetes, 41(8), pp. 909-913. (doi: 10.2337/diab.41.8.909) (PMID:1628764)

Book Sections

Lowe, G. and Bagot, C. (2014) Hemostasis and thrombosis. In: Baynes, J.W. and Dominiczak, M. (eds.) Medical Biochemistry [4th ed.]. Saunders/Elsevier: Edinburgh, pp. 68-81. ISBN 9781455745807