Dr Eline Huethorst

  • Research Associate (Cardiovascular & Metabolic Health)

Biography

Eline started her academic career in the Netherlands with an undergraduate in Life Sciences from the University of Groningen, where she gained interest in the field of Regenerative Medicine. She therefore decided to do a postgraduate in Regenerative Medicine at the University of Utrecht. Afterwards, she was awarded a 4-year PHD studentship by the British Heart Foundation and started working at the University of Glasgow to study how small, engineered heart tissues could integrate with the myocardium after implantation.

Eline is now a Research Associate at the University of Glasgow and part of the Glasgow Cardiac Research Centre. Eline is also part of the BHF Centre for Regenerative Medicine, which is a network of universities within the UK that all work together to tackle the big challenges within cardiac regeneration to be able to treat patients that have suffered a heart attack with new cell therapies in the future.

Research interests

Research Theme: Cardiac Diseases

Research groups

Publications

List by: Type | Date

Jump to: 2024 | 2022 | 2020 | 2016
Number of items: 8.

2024

Shead, K. D., Huethorst, E. , Burton, F., Lang, N. , Myles, R. C. and Smith, G. L. (2024) Human induced pluripotent stem cell derived cardiomyocytes for pre-clinical cardiotoxicity screening. JACC: CardioOncology, (Accepted for Publication)

Astrauskaite, G., Mohanan, S. , Williamson, L., Boland, E., Huethorst, E. , Kinegawa, R., Smith, G. and Muellenbroich, C. (2024) Remote Focusing for 2-photon Microscopy to Follow Action Potential Propagation Transmurally in Acute Rabbit Cardiac Slices. In: SPIE BiOS 2024, San Francisco, CA, USA, 27 January - 1 February 2024, ISBN 9781510669536 (doi: 10.1117/12.3002956)

Freeman, M., Huethorst, E. , Boland, E., Dunne, M., Burton, F., Denning, C., Myles, R. and Smith, G. (2024) A novel method for the percutaneous induction of myocardial infarction by occlusion of small coronary arteries in the rabbit. American Journal of Physiology: Heart and Circulatory Physiology, 326(3), H735--H751. (doi: 10.1152/ajpheart.00657.2023) (PMID:38180449)

Astrauskaitė, G., Williamson, L., Mohanan, S. , Moreno, S. M., Kinegawa, R., Boland, E., Huethorst, E. , Smith, G. and Müllenbroich, C. (2024) Fast Axial Scanning with Remote Focusing for Multiphoton Microscopy of Acute Rabbit Ventricular Slices to Follow Action Potentials Transmurally. In: Conference on Lasers and Electro-Optics (CLEO) 2024: Science and Innovations, Charlotte, North Carolina, USA, 05-10 May 2024, SF2B.1. ISBN 9781957171395 (doi: 10.1364/CLEO_SI.2024.SF2B.1)

2022

Huethorst, E. , Mortensen, P., Simitev, R. D. , Gao, H. , Pohjolainen, L., Talman, V., Ruskoaho, H., Burton, F. L., Gadegaard, N. and Smith, G. L. (2022) Conventional rigid 2D substrates cause complex contractile signals in monolayers of human induced pluripotent stem cell derived cardiomyocytes. Journal of Physiology, 600(3), pp. 483-507. (doi: 10.1113/JP282228) (PMID:34761809) (PMCID:PMC9299844)

2020

Huethorst, E. , Cutiongco, M. F.A. , Campbell, F. A., Saeed, A. , Love, R., Reynolds, P. M. , Dalby, M. J. and Gadegaard, N. (2020) Customizable, engineered substrates for rapid screening of cellular cues. Biofabrication, 12(2), 025009. (doi: 10.1088/1758-5090/ab5d3f) (PMID:31783378) (PMCID:PMC7655147)

2016

Huethorst, E., Hortigon, M. , Zamora-Rodriguez, V., Reynolds, P.M. , Burton, F., Smith, G. and Gadegaard, N. (2016) Enhanced human-induced pluripotent stem cell derived cardiomyocyte maturation using a dual microgradient substrate. ACS Biomaterials Science and Engineering, 2(12), pp. 2231-2239. (doi: 10.1021/acsbiomaterials.6b00426) (PMID:27990488) (PMCID:PMC5155309)

Huethorst, E. , Krebber, M. M., Fledderus, J. O., Gremmels, H., Xu, Y. J., Pei, J., Verhaar, M. C. and Cheng, C. (2016) Lymphatic Vascular Regeneration: The Next Step in Tissue Engineering. Tissue Engineering Part B: Reviews, 22(1), pp. 1-14. (doi: 10.1089/ten.teb.2015.0231) (PMID:26204330)

This list was generated on Thu Nov 14 21:05:12 2024 GMT.
Jump to: Articles | Conference Proceedings
Number of items: 8.

Articles

Shead, K. D., Huethorst, E. , Burton, F., Lang, N. , Myles, R. C. and Smith, G. L. (2024) Human induced pluripotent stem cell derived cardiomyocytes for pre-clinical cardiotoxicity screening. JACC: CardioOncology, (Accepted for Publication)

Freeman, M., Huethorst, E. , Boland, E., Dunne, M., Burton, F., Denning, C., Myles, R. and Smith, G. (2024) A novel method for the percutaneous induction of myocardial infarction by occlusion of small coronary arteries in the rabbit. American Journal of Physiology: Heart and Circulatory Physiology, 326(3), H735--H751. (doi: 10.1152/ajpheart.00657.2023) (PMID:38180449)

Huethorst, E. , Mortensen, P., Simitev, R. D. , Gao, H. , Pohjolainen, L., Talman, V., Ruskoaho, H., Burton, F. L., Gadegaard, N. and Smith, G. L. (2022) Conventional rigid 2D substrates cause complex contractile signals in monolayers of human induced pluripotent stem cell derived cardiomyocytes. Journal of Physiology, 600(3), pp. 483-507. (doi: 10.1113/JP282228) (PMID:34761809) (PMCID:PMC9299844)

Huethorst, E. , Cutiongco, M. F.A. , Campbell, F. A., Saeed, A. , Love, R., Reynolds, P. M. , Dalby, M. J. and Gadegaard, N. (2020) Customizable, engineered substrates for rapid screening of cellular cues. Biofabrication, 12(2), 025009. (doi: 10.1088/1758-5090/ab5d3f) (PMID:31783378) (PMCID:PMC7655147)

Huethorst, E., Hortigon, M. , Zamora-Rodriguez, V., Reynolds, P.M. , Burton, F., Smith, G. and Gadegaard, N. (2016) Enhanced human-induced pluripotent stem cell derived cardiomyocyte maturation using a dual microgradient substrate. ACS Biomaterials Science and Engineering, 2(12), pp. 2231-2239. (doi: 10.1021/acsbiomaterials.6b00426) (PMID:27990488) (PMCID:PMC5155309)

Huethorst, E. , Krebber, M. M., Fledderus, J. O., Gremmels, H., Xu, Y. J., Pei, J., Verhaar, M. C. and Cheng, C. (2016) Lymphatic Vascular Regeneration: The Next Step in Tissue Engineering. Tissue Engineering Part B: Reviews, 22(1), pp. 1-14. (doi: 10.1089/ten.teb.2015.0231) (PMID:26204330)

Conference Proceedings

Astrauskaite, G., Mohanan, S. , Williamson, L., Boland, E., Huethorst, E. , Kinegawa, R., Smith, G. and Muellenbroich, C. (2024) Remote Focusing for 2-photon Microscopy to Follow Action Potential Propagation Transmurally in Acute Rabbit Cardiac Slices. In: SPIE BiOS 2024, San Francisco, CA, USA, 27 January - 1 February 2024, ISBN 9781510669536 (doi: 10.1117/12.3002956)

Astrauskaitė, G., Williamson, L., Mohanan, S. , Moreno, S. M., Kinegawa, R., Boland, E., Huethorst, E. , Smith, G. and Müllenbroich, C. (2024) Fast Axial Scanning with Remote Focusing for Multiphoton Microscopy of Acute Rabbit Ventricular Slices to Follow Action Potentials Transmurally. In: Conference on Lasers and Electro-Optics (CLEO) 2024: Science and Innovations, Charlotte, North Carolina, USA, 05-10 May 2024, SF2B.1. ISBN 9781957171395 (doi: 10.1364/CLEO_SI.2024.SF2B.1)

This list was generated on Thu Nov 14 21:05:12 2024 GMT.