Number of items: 58.
2024
MacKenzie, S. M. , Birch, L. A., Lamprou, S., Rezvanisanijouybari, P., Fayad, M., Zennaro, M.-C. and Davies, E.
(2024)
MicroRNAs in aldosterone production and action.
In: Litwack, G. (ed.)
Vitamins and Hormones.
Series: Vitamins and hormones (124).
Elsevier: London, pp. 137-163.
ISBN 9780443194009
(doi: 10.1016/bs.vh.2023.07.001)
2023
Murphy, C. N., Delles, C. , Davies, E. and Connelly, P. J.
(2023)
Cardiovascular disease in transgender individuals.
Atherosclerosis, 384,
117282.
(doi: 10.1016/j.atherosclerosis.2023.117282)
(PMID:37821271)
2022
Reel, P. S. et al.
(2022)
Machine learning for classification of hypertension subtypes using multi-omics: a multi-centre, retrospective, data-driven study.
EBioMedicine, 84,
104276.
(doi: 10.1016/j.ebiom.2022.104276)
(PMID:36179553)
(PMCID:PMC9520210)
Pommer, G. et al.
(2022)
Preanalytical considerations and out-patient vs in-patient tests of plasma metanephrines to diagnose pheochromocytoma.
Journal of Clinical Endocrinology and Metabolism, 107(9),
e3689-e3698.
(doi: 10.1210/clinem/dgac390)
(PMID:35767279)
Bliziotis, N. G. et al.
(2022)
Preanalytical pitfalls in untargeted plasma nuclear magnetic resonance metabolomics of endocrine hypertension.
Metabolites, 12(8),
e679.
(doi: 10.3390/metabo12080679)
(PMID:35893246)
(PMCID:PMC9394285)
Reel, S. et al.
(2022)
Predicting hypertension subtypes with machine learning using targeted metabolites and their ratios.
Metabolites, 12(8),
755.
(doi: 10.3390/metabo12080755)
(PMID:36005627)
(PMCID:PMC9416693)
Armignacco, R. et al.
(2022)
Whole blood methylome-derived features to discriminate endocrine hypertension.
Clinical Epigenetics, 14,
142.
(doi: 10.1186/s13148-022-01347-y)
(PMID:36329530)
(PMCID:PMC9635165)
2021
MacKenzie, S. M. , Saunders, H., van Kralingen, J. C., Robertson, S. , Riddell, A. , Zennaro, M.-C. and Davies, E.
(2021)
Circulating microRNAs as diagnostic markers in primary aldosteronism.
Cancers, 13(21),
5312.
(doi: 10.3390/cancers13215312)
(PMCID:PMC8582381)
2019
MacKenzie, S. M. , Nguyen Dinh Cat, A., van Kralingen, J. and Davies, E.
(2019)
Aldosterone.
In: Touyz, R. M. and Delles, C. (eds.)
Textbook of Vascular Medicine.
Springer: Cham, pp. 103-115.
ISBN 9783030164805
(doi: 10.1007/978-3-030-16481-2_10)
MacKenzie, S. M. , Van Kralingen, J. C. and Davies, E.
(2019)
Regulation of aldosterone secretion.
In: Litwack, G. (ed.)
Aldosterone.
Series: Vitamins and Hormones (109).
Elsevier, pp. 241-263.
ISBN 9780128177822
(doi: 10.1016/bs.vh.2018.07.001)
2017
Robertson, S., Diver, L. A., Alvarez-Madrazo, S., Livie, C., Ejaz, A., Fraser, R., Connell, J. M., MacKenzie, S. M. and Davies, E.
(2017)
Regulation of corticosteroidogenic genes by microRNAs.
International Journal of Endocrinology, 2017,
2021903.
(doi: 10.1155/2017/2021903)
(PMID:28852406)
(PMCID:PMC5568613)
MacKenzie, S. M. , Freel, M., Connell, J. M., Fraser, R. and Davies, E.
(2017)
ACTH and polymorphisms at steroidogenic loci as determinants of aldosterone secretion and
blood pressure.
International Journal of Molecular Sciences, 18(3),
579.
(doi: 10.3390/ijms18030579)
(PMID:28272372)
(PMCID:PMC5372595)
MacKenzie, S. M. , Davies, E. and Alvarez-Madrazo, S.
(2017)
Analysis of the aldosterone synthase (CYP11B2) and 11β-hydroxylase (CYP11B1) genes.
In: Touyz, R. M. and Schiffrin, E. L. (eds.)
Hypertension: Methods and Protocols.
Series: Methods in molecular biology (1527).
Springer: New York, pp. 139-150.
ISBN 9781493966233
(doi: 10.1007/978-1-4939-6625-7_11)
2016
Diver, L. A. et al.
(2016)
Common polymorphisms at the CYP17A1 locus associate with steroid phenotype: support for blood pressure genome-wide association study signals at this locus.
Hypertension, 67(4),
pp. 724-732.
(doi: 10.1161/HYPERTENSIONAHA.115.06925)
(PMID:26902494)
(PMCID:PMC4789491)
Horikoshi, M. et al.
(2016)
Genome-wide associations for birth weight and correlations with adult disease.
Nature, 538(7624),
pp. 248-252.
(doi: 10.1038/nature19806)
(PMID:27680694)
(PMCID:PMC5164934)
2015
McManus, F., Fraser, R., Davies, E. , Connell, J.M.C. and Freel, E.M.
(2015)
Plasma steroid profiling and response to trophins to illustrate intra-adrenal dynamics.
Journal of Endocrinology, 224,
pp. 149-157.
(doi: 10.1530/JOE-14-0561)
2013
Robertson, S., MacKenzie, S. M. , Alvarez-Madrazo, S., Diver, L. A., Lin, J., Stewart, P. M., Fraser, R., Connell, J. M. and Davies, E.
(2013)
MicroRNA-24 is a novel regulator of aldosterone and cortisol production in the human adrenal cortex.
Hypertension, 62(3),
pp. 572-578.
(doi: 10.1161/HYPERTENSIONAHA.113.01102)
(PMID:23836801)
Alvarez-Madrazo, S. et al.
(2013)
Common polymorphisms in the CYP11B1 and CYP11B2 genes: evidence for a digenic influence on hypertension.
Hypertension, 61(1),
pp. 232-239.
(doi: 10.1161/HYPERTENSIONAHA.112.200741)
2012
Freel, E. M., Mark, P. B. , Weir, R. A.P., McQuarrie, E. P., Allan, K., Dargie, H. J., McClure, J. D. , Jardine, A. G. , Davies, E. and Connell, J. M.C.
(2012)
Demonstration of blood pressure-independent noninfarct myocardial fibrosis in primary aldosteronism: a cardiac magnetic resonance imaging study.
Circulation: Cardiovascular Imaging, 5(6),
pp. 740-747.
(doi: 10.1161/CIRCIMAGING.112.974576)
McManus, F., Sands, W., Diver, L., MacKenzie, S. M. , Fraser, R., Davies, E. and Connell, J. M.
(2012)
APEX1 regulation of aldosterone synthase gene transcription is disrupted by a common polymorphism in humans.
Circulation Research, 111(2),
pp. 212-219.
(doi: 10.1161/CIRCRESAHA.111.262931)
MacKenzie, S. M. , Connell, J. M.C. and Davies, E.
(2012)
Non-adrenal synthesis of aldosterone: A reality check.
Molecular and Cellular Endocrinology, 350(2),
pp. 163-167.
(doi: 10.1016/j.mce.2011.06.026)
2010
McNeilly, A. D. et al.
(2010)
Bile acids modulate glucocorticoid metabolism and the hypothalamic-pituitary-adrenal axis in obstructive jaundice.
Journal of Hepatology, 52(5),
pp. 705-711.
(doi: 10.1016/j.jhep.2009.10.037)
2009
Alvarez-Madrazo, S., Padmanabhan, S., Mayosi, B. M., Watkins, H., Avery, P., Wallace, A. M., Fraser, R., Davies, E., Connell, J. M. and Keavney, B.
(2009)
Familial and phenotypic associations of the aldosterone renin ratio.
Journal of Clinical Endocrinology and Metabolism, 94(11),
pp. 4324-4333.
(doi: 10.1210/jc.2009-1406)
Reynolds, R. M., Walker, B. R., Phillips, D. I., Dennison, E. M., Fraser, R., MacKenzie, S. M., Davies, E. and Connell, J. M.
(2009)
Programming of hypertension: associations of plasma aldosterone in adult men and women with birthweight, cortisol, and blood pressure.
Hypertension, 53(6),
pp. 932-936.
(doi: 10.1161/HYPERTENSIONAHA.109.129320)
Holloway, C.D. et al.
(2009)
Effects of genetic variation in the aldosterone synthase (CYP11B2) gene on enzyme function.
Clinical Endocrinology, 70(3),
pp. 363-371.
(doi: 10.1111/j.1365-2265.2008.03383.x)
Davies, E., Davies, E., Ainsworth, R., Aitken, C., Carman, W. and Kroes, A.
(2009)
Viral myocarditis.
Journal of Clinical Virology, 45(3),
VII-VIX.
2008
Huda, S. S., MacKenzie, S. M., Sattar, N., Fraser, R., Connell, J. M. C. and Davies, E.
(2008)
Depot-specific steroidogenic gene transcription in human adipose tissue.
Clinical Endocrinology, 69(6),
pp. 848-854.
(doi: 10.1111/j.1365-2265.2008.03262.x)
Freel, E.M., Ingram, M., Wallace, A.M., White, A., Fraser, R., Davies, E. and Connell, J.M.C.
(2008)
Effect of variation in CYP11B1 and CYP11B2 on corticosteroid phenotype and hypothalamic-pituitary-adrenal axis activity in hypertensive and normotensive subjects.
Clinical Endocrinology, 68(5),
pp. 700-706.
(doi: 10.1111/j.1365-2265.2007.03116.x)
Connell, J. M.C., MacKenzie, S. M. , Freel, E. M., Fraser, R. and Davies, E.
(2008)
A lifetime of aldosterone excess: long-term consequences of altered regulation of aldosterone production for cardiovascular function.
Endocrine Reviews, 29(2),
pp. 133-154.
(doi: 10.1210/er.2007-0030)
Ye, P., Kenyon, C. J., MacKenzie, S. M. , Nichol, K., Seckl, J. R., Fraser, R., Connell, J. M.C. and Davies, E.
(2008)
Effects of ACTH, dexamethasone, and adrenalectomy on 11 β-hydroxylase (CYP11B1) and aldosterone synthase(CYP11B2) gene expression in the rat central nervous system.
Journal of Endocrinology, 196(2),
pp. 305-311.
(doi: 10.1677/JOE-07-0439)
MacKenzie, S. M. , Dewar, D. , Stewart, W. , Fraser, R., Connell, J. M. C. and Davies, E.
(2008)
The transcription of steroidogenic genes in the human cerebellum and hippocampus: a comparative survey of normal and Alzheimer's tissue.
Journal of Endocrinology, 196(1),
pp. 123-130.
(doi: 10.1677/JOE-07-0427)
2007
Freel, E.M. et al.
(2007)
Phenotypic consequences of variation across the aldosterone synthase and 11-beta hydroxylase locus in a hypertensive cohort: data from the MRC BRIGHT Study.
Clinical Endocrinology, 67(6),
pp. 832-838.
(doi: 10.1111/j.1365-2265.2007.02971.x)
Freel, E.M., Bernhardt, M., Ingram, R., Wallace, A.M., Fraser, R., Davies, E. and Connell, J.M.C.
(2007)
Endogenous corticosteroid biosynthesis in subjects after bilateral adrenalectomy.
Clinical Endocrinology, 66(5),
pp. 659-665.
(doi: 10.1111/j.1365-2265.2007.02791.x)
Barr, M. et al.
(2007)
Polymorphic variation in the 11 beta-hydroxylase gene associates with reduced 11-hydroxylase efficiency.
Hypertension, 49(1),
pp. 113-119.
(doi: 10.1161/01.HYP.0000249904.93940.7a)
2006
Barr, M., MacKenzie, S. , Wilkinson, D., Holloway, C., Friel, E., Miller, S., MacDonald, T., Fraser, R., Connell, J. and Davies, E.
(2006)
Functional effects of genetic variants in the 11 beta-hydroxylase (CYP11B1) gene.
Clinical Endocrinology, 65,
pp. 816-825.
(doi: 10.1111/j.1365-2265.2006.02673.x)
Imrie, H. et al.
(2006)
Association between aldosterone production and variation in the 11 beta-hydroxylase (CYP11B1) gene.
Journal of Clinical Endocrinology and Metabolism, 91(12),
pp. 5051-5056.
(doi: 10.1210/jc.2006-1481)
2005
Ye, P. et al.
(2005)
The aldosterone synthase (CYP11B2) and 11 beta-hydroxylase (CYP11B1) genes are not expressed in the rat heart.
Endocrinology, 146(12),
pp. 5287-5293.
(doi: 10.1210/en.2005-0370)
(PMID:16179417)
Connell, J. and Davies, E.
(2005)
The new biology of aldosterone.
Journal of Endocrinology, 186,
pp. 1-20.
(doi: 10.1677/joe.1.06017)
Imrie, H., Mayosi, B., Baker, M., Fraser, R., Davies, E. , Ingram, M., Watkins, H., Farrall, M., Connell, J. and Keavney, B.
(2005)
Genetic variation at the locus encompassing 11-beta hydroxylase and aldosterone synthase accounts for heritability in cortisol precursor (11-deoxycortisol) urinary metabolite excretion.
Journal of Clinical Endocrinology and Metabolism, 90,
pp. 1072-1077.
(doi: 10.1210/jc.2004-0870)
2004
Freel, E., Shakerdi, L.A., Friel, E., Wallace, A.M., Davies, E., Fraser, R. and Connell, J.M.C.
(2004)
Studies on the origin of circulating 18-hydroxycortisol and 18-oxocortisol in normal human subjects.
Journal of Clinical Endocrinology and Metabolism, 89(9),
pp. 4628-4633.
(doi: 10.1210/jc.2004-0379)
Freel, E.M., Shakerdi, L., Friel, E., Wallace, A.M., Davies, E. , Fraser, R. and Connell, J.M.C.
(2004)
The origin of circulating 18-oxo and 18-hydroxycortisol in normal human subjects.
Journal of Clinical Endocrinology and Metabolism, 89(9),
pp. 4628-4633.
(doi: 10.1210/jc.2004-0379)
Connell, J. M.C., Fraser, R., MacKenzie, S. M. , Friel, E. C., Ingram, M. C., Holloway, C. D. and Davies, E.
(2004)
The impact of polymorphisms in the gene encoding aldosterone synthase (CYP11B2) on steroid synthesis and blood pressure regulation.
Molecular and Cellular Endocrinology, 217(1-2),
pp. 243-247.
(doi: 10.1016/j.mce.2003.10.025)
(PMID:15134824)
Kennon, B., Ingram, M., Friel, E., Anderson, N., MacKenzie, S. , Davies, E. , Shakerdi, L., Wallace, A., Fraser, R. and Connell, J.
(2004)
Aldosterone synthase gene variation and adrenocortical response to sodium status, angiotensin II and ACTH in normal male subjects.
Clinical Endocrinology, 61,
pp. 174-181.
(doi: 10.1111/j.1365-2265.2004.02073.x)
2003
Davies, E. and MacKenzie, S. M.
(2003)
Extra-adrenal production of corticosteroids.
Clinical and Experimental Pharmacology and Physiology, 30(7),
pp. 437-445.
(doi: 10.1046/j.1440-1681.2003.03867.x)
(PMID:12823256)
Connell, J., Fraser, R., MacKenzie, S. and Davies, E.
(2003)
Is altered adrenal steroid biosynthesis a key intermediate phenotype in hypertension?
Hypertension, 41,
pp. 993-999.
(doi: 10.1161/01.HYP.0000064344.00173.44)
Davies, E. and Kenyon, C.
(2003)
CYP11B2 polymorphisms and cardiovascular risk factors. [Editorial].
Journal of Hypertension, 21(7),
pp. 1249-1253.
Ye, P., Kenyon, C., MacKenzie, S. , Seckl, J., Fraser, R., Connell, J. and Davies, E.
(2003)
Regulation of aldosterone synthase gene expression in the rat adrenal gland and central nervous system by sodium and angiotensin II.
Endocrinology, 144,
pp. 3321-3328.
(doi: 10.1210/en.2003-0109)
2002
MacKenzie, S. M. , Fraser, R., Connell, J. M.C. and Davies, E.
(2002)
Local renin-angiotensin systems and their interactions with extra-adrenal corticosteroid production.
Journal of the Renin-Angiotensin-Aldosterone System, 3(4),
pp. 214-221.
(doi: 10.3317/jraas.2002.043)
(PMID:12584665)
Draper, N. et al.
(2002)
Association Studies between Microsatellite Markers within the Gene Encoding Human 11{beta}-Hydroxysteroid Dehydrogenase Type 1 and Body Mass Index, Waist to Hip Ratio, and Glucocorticoid Metabolism.
Journal of Clinical Endocrinology and Metabolism, 87(11),
pp. 4984-4990.
(doi: 10.1210/jc.2001-011375)
Lim, P., MacDonald, T., Holloway, C., Friel, E., Anderson, N., Dow, E., Jung, R., Davies, E. , Fraser, R. and Connell, J.
(2002)
Variation at the aldosterone synthase (CYP11B2) locus contributes to hypertension in subjects with a raised aldosterone-to-renin ratio.
Journal of Clinical Endocrinology and Metabolism, 87(9),
pp. 4398-4402.
MacKenzie, S. , Lai, M., Clark, C., Fraser, R., Gomez-Sanchez, C., Seckl, J., Connell, J. and Davies, E.
(2002)
11beta-hydroxylase and aldosterone synthase expression in fetal rat hippocampal neurons.
Journal of Molecular Endocrinology, 29(3),
pp. 319-325.
(doi: 10.1677/jme.0.0290319)
2001
Connell, J.M.C., Fraser, R. and Davies, E.
(2001)
Disorders of mineralocorticoid synthesis.
Best Practice and Research: Clinical Endocrinology and Metabolism, 15,
pp. 43-60.
(doi: 10.1053/beem.2000.0118)
Davies, E. , Holloway, C., Ingram, M., Friel, E., Inglis, G., Swan, L., Hillis, W., Fraser, R. and Connell, J.
(2001)
An influence of variation in the aldosterone synthase gene (CYP11B2) on corticosteroid responses to ACTH in normal human subjects.
Clinical Endocrinology, 54,
pp. 813-817.
Fisher, A., Friel, E., Bernhardt, R., Gomez-Sanchez, C., Connell, J., Fraser, R. and Davies, E.
(2001)
Effects of 18-hydroxylated steroids on corticosteroid production by human aldosterone synthase and 11 beta-hydroxylase.
Journal of Clinical Endocrinology and Metabolism, 86,
pp. 4326-4329.
Inglis, G., Plouin, P., Friel, E., Davies, E. , Fraser, R. and Connell, J.
(2001)
Polymorphic differences from normal in the aldosterone synthase gene (CYP11B2) in patients with primary hyperaldosteronism and adrenal tumour (Conn's syndrome).
Clinical Endocrinology, 54,
pp. 725-730.
2000
MacKenzie, S.M. , Clark, C.J., Fraser, R., Gomez-Sanchez, C.E., Connell, J. and Davies, E.
(2000)
Expression of 11 beta-hydroxylase and aldosterone synthase genes in the rat brain.
Journal of Molecular Endocrinology, 24(3),
pp. 321-328.
(doi: 10.1677/jme.0.0240321)
(PMID:10828825)
Clark, C.J., Davies, E. , Anderson, N.H., Farmer, R., Friel, E.C., Fraser, R. and Connell, J.M.C.
(2000)
alpha-adducin and angiotensin I-converting enzyme polymorphisms in essential hypertension.
Hypertension, 36(6),
pp. 990-994.
MacKenzie, S.M. , Clark, C.J., Ingram, M.C., Lai, M., Seckl, J., Gomez-Sanchez, C.E., Fraser, R., Connell, J.M.C. and Davies, E.
(2000)
Corticosteroid production by fetal rat hippocampal neurons.
Endocrine Research, 26(4),
pp. 531-535.
(doi: 10.3109/07435800009048566)
(PMID:11196425)
This list was generated on Mon Nov 4 06:44:11 2024 GMT.