Professor Peter Macfarlane
- Honorary Senior Research Fellow (School of Health & Wellbeing)
telephone:
0141 201 5410
email:
Peter.Macfarlane@glasgow.ac.uk
Electrocardiology Section, Level 1- New Lister Building, Royal Infirmary, Glasgow G31 2ER
Biography
Professor Macfarlane is Emeritus Professor and Hon Senior Research Fellow at the University of Glasgow. He was Professor in Medical Cardiology from 1991 – 1995 and Professor of Electrocardiology from 1995 – 2010. His major interest throughout has been the application of computer techniques to ECG interpretation. The work of his team has been adopted commercially and the University of Glasgow ECG interpretation program developed in his laboratory is currently used worldwide. He is particularly interested in differences in ECG appearances due to age, gender and ethnicity, and as a result, he has influenced international guidelines for the ECG definition of acute myocardial infarction. In addition, he has established an ECG Core Laboratory for handling ECGs recorded in national and international clinical trials and epidemiological studies.
Professor Macfarlane is a Fellow of many learned Societies, including the Royal Society of Edinburgh. In 2000, he was awarded a DSc on the basis of his contribution to research in his own field. He was also jointly awarded the 1998 Rijlant International Prize in Electrocardiology by the Belgian Royal Academy of Medicine. In January 2014, he was awarded a CBE for Services to Healthcare.
Publications
2024
Porr, B. and Macfarlane, P. W. (2024) A new QRS detector stress test combining temporal jitter and F-score (JF) reveals significant performance differences amongst popular detectors. PLoS ONE, 19(11), e0309739. (doi: 10.1371/journal.pone.0309739) (PMID:39527567) (PMCID:PMC11554035)
Morrow, A. et al. (2024) Zibotentan in microvascular angina: a randomized, placebo-controlled, crossover trial. Circulation, (doi: 10.1161/CIRCULATIONAHA.124.069901) (PMID:39217504) (Early Online Publication)
Ensam, B. et al. (2024) Type 1 Brugada pattern may be provoked by ajmaline in some healthy subjects: results from a clinical trial. Circulation, 149(21), pp. 1693-1695. (doi: 10.1161/circulationaha.123.067223) (PMID:38768273) (PMCID:PMC11115450)
Joy, G. et al. (2024) Electrophysiological characterization of subclinical and overt hypertrophic cardiomyopathy by magnetic resonance imaging-guided electrocardiography. Journal of the American College of Cardiology, 83(11), pp. 1042-1055. (doi: 10.1016/j.jacc.2024.01.006) (PMID:38385929) (PMCID:PMC10945386)
Morrow, A. J. et al. (2024) Socioeconomic deprivation and illness trajectory in the Scottish population after COVID-19 hospitalization. Communications Medicine, 4, 32. (doi: 10.1038/s43856-024-00455-5) (PMID:38418616) (PMCID:PMC10901805)
2023
Berry, C. et al. (2023) Mental health symptoms and illness trajectory following COVID-19 hospitalization: A cohort study. Heart and Mind, 7(4), pp. 235-245. (doi: 10.4103/hm.HM-D-23-00037)
Joy, G. et al. (2023) Microstructural and microvascular phenotype of sarcomere mutation carriers and overt hypertrophic cardiomyopathy. Circulation, 148(10), pp. 808-818. (doi: 10.1161/circulationaha.123.063835) (PMID:37463608) (PMCID:PMC10473031)
van de Vegte, Y. J. et al. (2023) Genetic insights into resting heart rate and its role in cardiovascular disease. Nature Communications, 14(1), 4646. (doi: 10.1038/s41467-023-39521-2) (PMID:37532724) (PMCID:PMC10397318)
Young, W. J. et al. (2023) Genetic architecture of spatial electrical biomarkers for cardiac arrhythmia and relationship with cardiovascular disease. Nature Communications, 14, 1411. (doi: 10.1038/s41467-023-36997-w) (PMID:36918541) (PMCID:PMC10015012)
Artico, J. et al. (2023) Myocardial involvement after hospitalization for COVID-19 complicated by troponin elevation: a prospective, multicenter, observational study. Circulation, 147(5), pp. 364-374. (doi: 10.1161/CIRCULATIONAHA.122.060632) (PMID:36705028) (PMCID:PMC9889203)
Sykes, R. et al. (2023) Adjudicated myocarditis and multisystem illness trajectory in healthcare workers post-COVID-19. Open Heart, 10(1), e002192. (doi: 10.1136/openhrt-2022-002192) (PMID:36822817) (PMCID:PMC9950584)
2022
Brandes, A. et al. (2022) Consumer-led screening for atrial fibrillation: Frontier review of the AF-SCREEN International Collaboration. Circulation, 146(19), pp. 1461-1474. (doi: 10.1161/circulationaha.121.058911) (PMID:36343103)
Young, W. J. et al. (2022) Genetic analyses of the electrocardiographic QT interval and its components identify additional loci and pathways. Nature Communications, 13, 5144. (doi: 10.1038/s41467-022-32821-z) (PMID:36050321) (PMCID:PMC9436946)
Al-Zaiti, S. S., Alghwiri, A. A., Hu, X., Clermont, G., Peace, A., Macfarlane, P. and Bond, R. (2022) A clinician’s guide to understanding and critically appraising machine learning studies: a checklist for Ruling Out Bias Using Standard Tools in Machine Learning (ROBUST-ML). European Heart Journal: Digital Health, 3(2), pp. 125-140. (doi: 10.1093/ehjdh/ztac016) (PMID:36713011) (PMCID:PMC9708024)
Morrow, A. J. et al. (2022) A multisystem, cardio-renal investigation of post-COVID-19 illness. Nature Medicine, 28(6), pp. 1303-1313. (doi: 10.1038/s41591-022-01837-9) (PMID:35606551) (PMCID:PMC9205780)
Siland, J. E. et al. (2022) Resting heart rate and incident atrial fibrillation: A stratified Mendelian randomization in the AFGen consortium. PLoS ONE, 17(5), e0268768. (doi: 10.1371/journal.pone.0268768) (PMID:35594314) (PMCID:PMC9122202)
de Groot, N. M.S. et al. (2022) Critical appraisal of technologies to assess electrical activity during atrial fibrillation: a position paper from the European Heart Rhythm Association and European Society of Cardiology Working Group on eCardiology in collaboration with the Heart Rhythm Society, Asia Pacific Heart Rhythm Society, Latin American Heart Rhythm Society and Computing in Cardiology. Europace, 24(2), pp. 313-330. (doi: 10.1093/europace/euab254) (PMID:34878119)
Macfarlane, P. W. (2022) The application of computer techniques to ECG interpretation. Hearts, 3(1), pp. 1-5. (doi: 10.3390/hearts3010001)
2021
Macfarlane, P. W. and Kennedy, J. (2021) Automated ECG interpretation—a brief history from high expectations to deepest networks. Hearts, 2(4), pp. 433-448. (doi: 10.3390/hearts2040034)
Paixão, G. M. M., Lima, E. M., Gomes, P. R., Oliveira, D. M., Ribeiro, M. H., Nascimento, J. S., Ribeiro, A. H., Macfarlane, P. W. and Ribeiro, A. L. P. (2021) Electrocardiographic predictors of mortality: data from a primary care tele-electrocardiography cohort of Brazilian patients. Hearts, 2(4), pp. 449-458. (doi: 10.3390/hearts2040035)
Berry, C. et al. (2021) Post-COVID-19 illness trajectory: a multisystem investigation [Pre-print]. Research Square, (doi: 10.21203/rs.3.rs-1053331/v1)
Morrow, A. et al. (2021) Rationale and design of the Medical Research Council Precision medicine with Zibotentan in microvascular angina (PRIZE) trial MRI sub-study. British Society of Cardiovascular Magnetic Resonance 2021 Annual Meeting, 12 October 2021. A2.1-A2. (doi: 10.1136/heartjnl-2021-BSCMR.3)
Rubel, P., Fayn, J., Macfarlane, P. W., Pani, D., Schlögl, A. and Värri, A. (2021) The history and challenges of SCP-ECG: the standard communication protocol for computer-assisted electrocardiography. Hearts, 2(3), pp. 384-409. (doi: 10.3390/hearts2030031)
Gorecka, M. et al. (2021) Demographic, multi-morbidity and genetic impact on myocardial involvement and its recovery from COVID-19: protocol design of COVID-HEART—a UK, multicentre, observational study. Journal of Cardiovascular Magnetic Resonance, 23, 77. (doi: 10.1186/s12968-021-00752-1) (PMID:34112195) (PMCID:PMC8190746)
Maznyczka, A. M. et al. (2021) Effect of coronary flow on intracoronary alteplase: a prespecified analysis from a randomised trial. Heart, 107(4), pp. 299-312. (doi: 10.1136/heartjnl-2020-317828) (PMID:33436493)
2020
Mangion, K. et al. (2020) The Chief Scientist Office cardiovascular and pulmonary imaging in SARS Coronavirus disease-19 (CISCO-19) study. Cardiovascular Research, 116(14), pp. 2185-2196. (doi: 10.1093/cvr/cvaa209) (PMID:32702087) (PMCID:PMC7454350)
McCartney, P. J. et al. (2020) Low-dose intracoronary alteplase during primary percutaneous coronary intervention in patients with acute myocardial infarction: the T-TIME three-arm RCT. Efficacy and Mechanism Evaluation, 7(5), (doi: 10.3310/eme07050) (PMID:33175484)
Morrow, A. J. et al. (2020) Rationale and design of the Medical Research Council precision medicine with Zibotentan in microvascular angina (PRIZE) trial. American Heart Journal, 229, pp. 70-80. (doi: 10.1016/j.ahj.2020.07.007) (PMID:32942043)
Macfarlane, P. W. (2020) New ECG criteria for acute myocardial infarction in patients with left bundle branch block. Journal of the American Heart Association, 9(14), e017119. (doi: 10.1161/jaha.120.017119) (PMID:32627635)
Ntalla, I. et al. (2020) Multi-ancestry GWAS of the electrocardiographic PR interval identifies 202 loci underlying cardiac conduction. Nature Communications, 11, 2542. (doi: 10.1038/s41467-020-15706-x) (PMID:32439900) (PMCID:PMC7242331)
Ribeiro, A. H. et al. (2020) Automatic diagnosis of the 12-lead ECG using a deep neural network. Nature Communications, 11, 1760. (doi: 10.1038/s41467-020-15432-4) (PMID:32273514) (PMCID:PMC7145824)
Zonneveld, M. H., Noordam, R., Grond, J., Sabayan, B., Mooijaart, S. P., Macfarlane, P. W., Jukema, J. W. and Trompet, S. (2020) Ventricular repolarization is associated with cognitive function, but not with cognitive decline and brain Magnetic Resonance Imaging (MRI) measurements in older adults. Journal of Clinical Medicine, 9(4), e911. (doi: 10.3390/jcm9040911)
Maznyczka, A. M. et al. (2020) Effects of intracoronary alteplase on microvascular function in acute myocardial infarction. Journal of the American Heart Association, 9(3), e014066. (doi: 10.1161/JAHA.119.014066) (PMID:31986989) (PMCID:PMC7033872)
2019
Ribeiro, A. L. P. et al. (2019) Tele-electrocardiography and bigdata: the CODE (Clinical Outcomes in Digital Electrocardiography) study. Journal of Electrocardiology, 57(Suppl), S75-S78. (doi: 10.1016/j.jelectrocard.2019.09.008) (PMID:31526573)
Kitas, G. D. et al. (2019) A multicenter, randomized, placebo‐controlled trial of atorvastatin for the primary prevention of cardiovascular events in patients with rheumatoid arthritis. Arthritis and Rheumatology, 71(9), pp. 1437-1449. (doi: 10.1002/art.40892) (PMID:30983166) (PMCID:PMC6771601)
Walsh, B., Macfarlane, P. W., Prutkin, J. M. and Smith, S. W. (2019) Distinctive ECG patterns in healthy black adults. Journal of Electrocardiology, 56, pp. 15-23. (doi: 10.1016/j.jelectrocard.2019.06.007) (PMID:31229678)
van Setten, J. et al. (2019) Genome-wide association meta-analysis of 30,000 samples identifies seven novel loci for quantitative ECG traits. European Journal of Human Genetics, 27(6), pp. 952-962. (doi: 10.1038/s41431-018-0295-z) (PMID:30679814) (PMCID:PMC6777533)
Armitage, J. et al. (2019) Efficacy and safety of statin therapy in older people: a meta-analysis of individual participant data from 28 randomised controlled trials. Lancet, 393(10170), pp. 407-415. (doi: 10.1016/S0140-6736(18)31942-1) (PMID:30712900) (PMCID:PMC6429627)
Ellervik, C. et al. (2019) Assessment of the relationship between genetic determinants of thyroid function and atrial fibrillation: a Medelian randomization study. JAMA Cardiology, 4(2), pp. 144-152. (doi: 10.1001/jamacardio.2018.4635) (PMID:30673084) (PMCID:PMC6396813)
Mahinrad, S. et al. (2019) Spatial QRS-T angle and cognitive decline in older subjects. Journal of Alzheimer's Disease, 67(1), pp. 279-289. (doi: 10.3233/JAD-180633) (PMID:30584139)
Elffers, T.W., Trompet, S., de Mutsert, R., Maan, A.C., Lamb, H.J., Macfarlane, P.W., Rosendaal, F.R. and Jukema, J.W. (2019) Borderline Q-waves in individuals without overt cardiovascular disease: relations with adiposity, subclinical atherosclerosis and vascular stiffness. International Journal of Cardiology, 274, pp. 331-336. (doi: 10.1016/j.ijcard.2018.08.088) (PMID:30195838)
McCartney, P. J. et al. (2019) Effect of low-dose intracoronary alteplase during primary percutaneous coronary intervention on microvascular obstruction in patients with acute myocardial infarction: a randomized clinical trial. JAMA: Journal of the American Medical Association, 321(1), pp. 56-68. (doi: 10.1001/jama.2018.19802) (PMID:30620371) (PMCID:PMC6583564)
2018
Pulit, S. L. et al. (2018) Atrial fibrillation genetic risk differentiates cardioembolic stroke from other stroke subtypes. Neurology Genetics, 4(6), e293. (doi: 10.1212/NXG.0000000000000293) (PMID:30584597) (PMCID:PMC6283455)
Roselli, C. et al. (2018) Multi-ethnic genome-wide association study for atrial fibrillation. Nature Genetics, 50(9), pp. 1225-1233. (doi: 10.1038/s41588-018-0133-9) (PMID:29892015)
Van Setten, J. et al. (2018) PR interval genome-wide association meta-analysis identifies 50 loci associated with atrial and atrioventricular electrical activity. Nature Communications, 9, 2904. (doi: 10.1038/s41467-018-04766-9) (PMID:30046033) (PMCID:PMC6060178)
Kligfield, P. et al. (2018) Comparison of automated interval measurements by widely used algorithms in digital electrocardiographs. American Heart Journal, 200, pp. 1-10. (doi: 10.1016/j.ahj.2018.02.014)
Clark, E. and Macfarlane, P. (2018) Specificity of New Diagnostic Criteria for Left Ventricular Hypertrophy. In: Computing in Cardiology 2017, Rennes, France, 24-27 Sept 2017, (doi: 10.22489/CinC.2017.013-116)
Seyerle, A. A. et al. (2018) Pharmacogenomics study of thiazide diuretics and QT interval in multi-ethnic populations: the cohorts for heart and aging research in genomic epidemiology. Pharmacogenomics Journal, 18(2), pp. 215-226. (doi: 10.1038/tpj.2017.10) (PMID:28719597) (PMCID:PMC5773415)
Elffers, T. W., de Mutsert, R., Lamb, H. J., Maan, A. C., Macfarlane, P. W., Willems van Dijk, K., Rosendaal, F. R., Jukema, J. W. and Trompet, S. (2018) Relation of overall and abdominal adiposity with electrocardiogram parameters of subclinical cardiovascular disease in individuals aged 45 to 65 years (from the Netherlands Epidemiology of Obesity Study). American Journal of Cardiology, 121(5), pp. 570-578. (doi: 10.1016/j.amjcard.2017.11.030) (PMID:29310809)
2017
Baumgartner, C. et al. (2017) Thyroid function within the normal range, subclinical hypothyroidism and the risk of atrial fibrillation. Circulation, 136(22), pp. 2100-2116. (doi: 10.1161/CIRCULATIONAHA.117.028753) (PMID:29061566)
Macfarlane, P. W., Mason, J. W., Kligfield, P., Sommargren, C. E., Drew, B., van Dam, P., Abächerli, R., Albert, D. E. and Hodges, M. (2017) Debatable issues in automated ECG reporting. Journal of Electrocardiology, 50(6), pp. 833-840. (doi: 10.1016/j.jelectrocard.2017.08.027) (PMID:28985886)
Weng, L.-C. et al. (2017) Genetic interactions with age, sex, body mass index, and hypertension in relation to atrial fibrillation: the AFGen consortium. Scientific Reports, 7, 11303. (doi: 10.1038/s41598-017-09396-7) (PMID:28900195) (PMCID:PMC5595875)
Iacoviello, L. et al. (2017) Frontal plane T-wave axis orientation predicts coronary events: Findings from the Moli-sani study. Atherosclerosis, 264, pp. 51-57. (doi: 10.1016/j.atherosclerosis.2017.07.021) (PMID:28772106)
Ray, D., Hazra, S., Goswami, D. P., Macfarlane, P. W. and Sengupta, A. (2017) An evaluation of planarity of the spatial QRS loop by three dimensional vectorcardiography: its emergence and loss. Journal of Electrocardiology, 50(5), pp. 652-660. (doi: 10.1016/j.jelectrocard.2017.03.016) (PMID:28366419)
Schutte, R., Whincup, P. H., Papacosta, O., Lennon, L. T., Macfarlane, P. W. and Wannamethee, G. (2017) Liver enzymes are not directly involved in atrial fibrillation: a prospective cohort study. European Journal of Clinical Investigation, 47(8), pp. 583-590. (doi: 10.1111/eci.12779) (PMID:28664600)
Pinto-Filho, M. M. et al. (2017) Major electrocardiographic abnormalities according to the Minnesota coding system among Brazilian adults (from the ELSA-Brasil cohort study). American Journal of Cardiology, 119(12), pp. 2081-2087. (doi: 10.1016/j.amjcard.2017.03.043) (PMID:28450038)
van den Berg, M. E. et al. (2017) Discovery of novel heart rate-associated loci using the Exome Chip. Human Molecular Genetics, 26(12), pp. 2346-2363. (doi: 10.1093/hmg/ddx113) (PMID:28379579) (PMCID:PMC5458336)
Palhares, D. M.F., Marcolino, M. S., Santos, T. M.M., da Silva, J. L.P., Gomes, P. R., Ribeiro, L. B., Macfarlane, P. W. and Ribeiro, A. L.P. (2017) Normal limits of the electrocardiogram derived from a large database of Brazilian primary care patients. BMC Cardiovascular Disorders, 17(1), 152. (doi: 10.1186/s12872-017-0572-8) (PMID:28610624) (PMCID:PMC5470250)
Christophersen, I. E. et al. (2017) Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation. Nature Genetics, 49(6), pp. 946-952. (doi: 10.1038/ng.3843) (PMID:28416818)
Elffers, T. W., de Mutsert, R., Lamb, H. J., Maan, A. C., Macfarlane, P. W., Willems van Dijk, K., Rosendaal, F. R., Jukema, J. W. and Trompet, S. (2017) Association of metabolic syndrome and electrocardiographic markers of subclinical cardiovascular disease. Diabetology and Metabolic Syndrome, 9, 40. (doi: 10.1186/s13098-017-0238-9) (PMID:28539979) (PMCID:PMC5441065)
Lubitz, S. A. et al. (2017) Genetic risk prediction of atrial fibrillation. Circulation, 135(14), pp. 1311-1320. (doi: 10.1161/CIRCULATIONAHA.116.024143) (PMID:27793994)
Stam-Slob, M. C. et al. (2017) Personalized absolute benefit of statin treatment for primary or secondary prevention of vascular disease in individual elderly patients. Clinical Research in Cardiology, 106(1), pp. 58-68. (doi: 10.1007/s00392-016-1023-8) (PMID:27554244) (PMCID:PMC5226996)
Bosson, N. et al. (2017) Causes of prehospital misinterpretations of ST elevation myocardial infarction. Prehospital Emergency Care, 21(3), pp. 283-290. (doi: 10.1080/10903127.2016.1247200) (PMID:27858506)
Mahinrad, S., Vriend, A. E., Jukema, J. W., van Heemst, D., Sattar, N. , Blauw, G. J., Macfarlane, P. W., Clark, E. N., de Craen, A. J.M. and Sabayan, B. (2017) Left ventricular hypertrophy and cognitive decline in old age. Journal of Alzheimer's Disease, 58(1), pp. 275-283. (doi: 10.3233/JAD-161150) (PMID:28387665)
2016
Lin, H. et al. (2016) Gene-gene interaction analyses for atrial fibrillation. Scientific Reports, 6, 35371. (doi: 10.1038/srep35371) (PMID:27824142) (PMCID:PMC5099695)
van der Harst, P. et al. (2016) 52 genetic loci influencing myocardial mass. Journal of the American College of Cardiology, 68(13), pp. 1435-1448. (doi: 10.1016/j.jacc.2016.07.729) (PMID:27659466) (PMCID:PMC5478167)
Batchvarov, V. N., Bastiaenen, R., Postema, P. G., Clark, E., Macfarlane, P., Wilde, A. A.M. and Behr, E. R. (2016) Novel electrocardiographic criteria for the diagnosis of arrhythmogenic right ventricular cardiomyopathy. Europace, 18(9), pp. 1420-1426. (doi: 10.1093/europace/euv379) (PMID:26622053)
Salvi, V., Clark, E., Karnad, D. R., Macfarlane, P. W., Panicker, G. K., Hingorani, P. and Kothari, S. (2016) Comparison of the spatial QRS-T angle derived from digital ECGs recorded using conventional electrode placement with that derived from Mason-Likar electrode position. Journal of Electrocardiology, 49(5), pp. 714-719. (doi: 10.1016/j.jelectrocard.2016.06.006) (PMID:27395365)
Mahinrad, S., Jukema, J. W., van Heemst, D. v., Macfarlane, P. W., Clark, E. N., de Craen, A. J.M. and Sabayan, B. (2016) 10-Second heart rate variability and cognitive function in old age. Neurology, 86(12), pp. 1120-1127. (doi: 10.1212/wnl.0000000000002499) (PMID:26888988)
2015
Drew, B. J., Sommargren, C. E., Tolan, G. D., Macfarlane, P. W., Wagner, G. S., Strauss, D. G., Burke, M. C., Kligfield, P. D., Rowlandson, I. and Lux, R. L. (2015) In memoriam: a tribute to the work and lives of Ron Selvester and Rory Childers. Journal of Electrocardiology, 48(6), pp. 1088-1098. (doi: 10.1016/j.jelectrocard.2015.08.037) (PMID:26422547)
Ogliari, G. et al. (2015) Resting heart rate, heart rate variability and functional decline in old age. Canadian Medical Association Journal, 187(15), E442-E449. (doi: 10.1503/cmaj.150462) (PMID:26323697) (PMCID:PMC4610849)
Macfarlane, P.W., Antzelevitch, C., Haissaguerre, M., Huikuri, H.V., Potse, M., Rosso, R., Sacher, F., Tikkanen, J.T., Wellens, H. and Yan, G.-X. (2015) The early repolarization pattern. Journal of the American College of Cardiology, 66(4), pp. 470-477. (doi: 10.1016/j.jacc.2015.05.033)
Macfarlane, P. W., Lloyd, S. M. , Singh, D., Hamde, S., Clark, E., Devine, B., Francq, B. G. and Kumar, V. (2015) Normal limits of the electrocardiogram in Indians. Journal of Electrocardiology, 48(4), pp. 652-668. (doi: 10.1016/j.jelectrocard.2015.04.013) (PMID:25990450)
Macfarlane, P. W. (2015) Normal limits of ECG measurements related to atrial activity using a modified limb lead system. Anadolu Kardiyoloji Dergisi/The Anatolian Journal of Cardiology, 15(1), p. 7. (doi: 10.5152/akd.2014.14170) (PMID:25550246)
2014
Macfarlane, P.W., Katibi, I.A., Hamde, S.T., Singh, D., Clark, E., Devine, B., Francq, B., Lloyd, S. and Kumar, V. (2014) Racial differences in the ECG — selected aspects. Journal of Electrocardiology, 47(6), pp. 809-814. (doi: 10.1016/j.jelectrocard.2014.08.003)
Arking, D. E. et al. (2014) Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization. Nature Genetics, 46(8), pp. 826-836. (doi: 10.1038/ng.3014) (PMID:24952745) (PMCID:PMC4124521)
Higgins, P., Dawson, J. , Macfarlane, P. W., McArthur, K., Langhorne, P. and Lees, K. R. (2014) Predictive value of newly detected atrial fibrillation paroxysms in patients with acute ischemic stroke, for atrial fibrillation after 90 days. Stroke, 45(7), pp. 2134-2136. (doi: 10.1161/STROKEAHA.114.005405)
Lubitz, S.A. et al. (2014) Novel genetic markers associate with atrial fibrillation risk in Europeans and Japanese. Journal of the American College of Cardiology, 63(12), pp. 1200-1210. (doi: 10.1016/j.jacc.2013.12.015)
Clark, E. N., Katibi, I. and Macfarlane, P. W. (2014) Automatic detection of end QRS notching or slurring. Journal of Electrocardiology, 47(2), pp. 151-154. (doi: 10.1016/j.jelectrocard.2013.10.007)
Kligfield, P. et al. (2014) Comparison of automated measurements of electrocardiographic intervals and durations by computer-based algorithms of digital electrocardiographs. American Heart Journal, 167(2), 150-159.e1. (doi: 10.1016/j.ahj.2013.10.004) (PMID:24439975) (PMCID:24439975)
Lundby, A. et al. (2014) Annotation of loci from genome-wide association studies using tissue-specific quantitative interaction proteomics. Nature Methods, 11(8), pp. 868-874. (doi: 10.1038/NMETH.2997)
Sinner, M. F. et al. (2014) Integrating genetic, transcriptional, and functional analyses to identify 5 novel genes for atrial fibrillation. Circulation, 130(15), pp. 1225-1235. (doi: 10.1161/CIRCULATIONAHA.114.009892)
2013
Macfarlane, P.W., Clark, E.N. and Heng, J.S. (2013) J wave patterns—morphology, prevalence and nomenclature. Journal of Electrocardiology, 46(6), pp. 505-509. (doi: 10.1016/j.jelectrocard.2013.08.013)
Macfarlane, P.W. (2013) The continuing renaissance of the resting 10s ECG. Journal of Electrocardiology, 46(5), pp. 383-384. (doi: 10.1016/j.jelectrocard.2013.06.029)
Macfarlane, P.W. and Clark, E.N. (2013) ECG measurements in end QRS notching and slurring. Journal of Electrocardiology, 46(5), pp. 385-389. (doi: 10.1016/j.jelectrocard.2013.06.011)
Katibi, I., Clark, E.N., Devine, B., Lloyd, S.M. and Macfarlane, P.W. (2013) Normal limits of the electrocardiogram in Nigerians. Journal of Electrocardiology, 46(4), pp. 289-295. (doi: 10.1016/j.jelectrocard.2013.04.002)
Nanchen, D. et al. (2013) Resting heart rate and incident heart failure and cardiovascular mortality in older adults: role of inflammation and endothelial dysfunction: the PROSPER study. European Journal of Heart Failure, 15(5), pp. 581-588. (doi: 10.1093/eurjhf/hfs195)
Higgins, P., Macfarlane, P. W., Dawson, J. , McInnes, G. T., Langhorne, P. and Lees, K. R. (2013) Noninvasive cardiac event monitoring to detect atrial fibrillation after ischemic stroke: a randomized, controlled trial. Stroke, 44(9), pp. 2525-2531. (doi: 10.1161/STROKEAHA.113.001927)
Welsh, P. , Doolin, O., Willeit, P., Packard, C. , Macfarlane, P., Cobbe, S., Gudnason, V., Di Angelantonio, E., Ford, I. and Sattar, N. (2013) N-terminal pro-B-type natriuretic peptide and the prediction of primary cardiovascular events: results from 15-year follow-up of WOSCOPS. European Heart Journal, 34(6), pp. 443-450. (doi: 10.1093/eurheartj/ehs239)
2012
Heng, S.J., Clark, E.N. and Macfarlane, P.W. (2012) End QRS notching or slurring in the electrocardiogram: influence on the definition of "early repolarization". Journal of the American College of Cardiology, 60(10), pp. 947-948. (doi: 10.1016/j.jacc.2012.03.061)
Mihaylova, B. et al. (2012) The effects of lowering LDL cholesterol with statin therapy in people at low risk of vascular disease: meta-analysis of individual data from 27 randomised trials. Lancet, 380(9841), pp. 581-590. (doi: 10.1016/S0140-6736(12)60367-5)
Nanchen, D. et al. (2012) Subclinical thyroid dysfunction and the risk of heart failure in older persons at high cardiovascular risk. Journal of Clinical Endocrinology and Metabolism, 97(3), pp. 852-861. (doi: 10.1210/jc.2011-1978)
Devine, B., Clark, E., Luo, S. and Macfarlane, P.W. (2012) Critical Values in the Uni-G Program. In: 39th Conference on Computing in Cardiology, Krakow, POLAND, SEP 09-12, 2012,
Emberson, J.R. et al. (2012) Lack of effect of lowering LDL cholesterol on cancer: meta-analysis of individual data from 175,000 people in 27 randomised trials of statin therapy. PLoS ONE, 7(1), e29849. (doi: 10.1371/journal.pone.0029849) (PMID:22276132) (PMCID:PMC3261846)
Gaunt, T.R. et al. (2012) Integration of genetics into a systems model of electrocardiographic traits using humanCVD BeadChip. Circulation: Cardiovascular Genetics, 5(6), pp. 630-638. (doi: 10.1161/CIRCGENETICS.112.962852)
Lindekliev, H., Wilsgaard, T., Macfarlane, P.W. and Lochen, M. (2012) QT interval and the risk of myocardial infarction and all-cause death: A cohort study. Journal of Cardiovascular Electrophysiology, 23(8), pp. 846-852. (doi: 10.1111/j.1540-8167.2012.02308.x)
Luo, S., Johnston, P. and Macfarlane, P.W. (2012) Implanted cardiac pacemaker pulses as recorded from the body surface. Journal of Electrocardiology, 45(6), pp. 663-669. (doi: 10.1016/j.jelectrocard.2012.08.008)
Pierce, M.B. et al. (2012) Clinical disorders in a post war British cohort reaching retirement: evidence from the First National Birth Cohort Study. PLoS ONE, 7(9), e44857. (doi: 10.1371/journal.pone.0044857) (PMID:23028647) (PMCID:PMC3447001)
2011
van Es, A.C.G.M. et al. (2011) Cerebral microbleeds and cognitive functioning in the PROSPER study. Neurology, 77(15), pp. 1446-1452. (doi: 10.1212/WNL.0b013e318232ab1d)
Widya, R. L. et al. (2011) Increased amygdalar and hippocampal volumes in elderly obese individuals with or at risk of cardiovascular disease. American Journal of Clinical Nutrition, 93(6), pp. 1190-1195. (doi: 10.3945/ajcn.110.006304)
Logue, J. , Murray, H.M., Welsh, P. , Shepherd, J., Packard, C. , Macfarlane, P., Cobbe, S., Ford, I. and Sattar, N. (2011) Obesity is associated with fatal coronary heart disease independently of traditional risk factors and deprivation. Heart, 97(7), pp. 564-568. (doi: 10.1136/hrt.2010.211201)
Rahimi, K. et al. (2011) Effect of statins on atrial fibrillation: collaborative meta-analysis of published and unpublished evidence from randomised controlled trials. British Medical Journal, 342, d1250. (doi: 10.1136/bmj.d1250)
Macfarlane, P.W., Murray, H., Sattar, N. , Stott, D.J. , Ford, I. , Buckley, B., Jukema, J.W., Westendorp, R.G.J. and Shepherd, J. (2011) The incidence and risk factors for new onset atrial fibrillation in the PROSPER study. Europace, 13(5), pp. 634-639. (doi: 10.1093/europace/eur016)
Mutsaerts, H.J.M.M. et al. (2011) Diastolic carotid artery wall shear stress is associated with cerebral infarcts and periventricular white matter lesions. Stroke, 42(12), pp. 3497-3501. (doi: 10.1161/STROKEAHA.111.614453)
Nunn, L.M., Bhar-Amato, J., Lowe, M.D., Macfarlane, P.W., Rogers, P., McKenna, W.J., Elliott, P.M. and Lambiase, P. D. (2011) Prevalence of J-Point Elevation in Sudden Arrhythmic Death Syndrome Families. Journal of the American College of Cardiology, 58(3), pp. 286-290. (doi: 10.1016/j.jacc.2011.03.028)
Pons, D. et al. (2011) Genetic variation in PCAF, a key mediator in epigenetics, is associated with reduced vascular morbidity and mortality: evidence for a new concept from three independent prospective studies. Heart, 97(2), pp. 143-150. (doi: 10.1136/hrt.2010.199927)
Reinhard, W., Kaess, B. M., Debiec, R., Nelson, C. P., Stark, K., Tobin, M. D., Macfarlane, P.W., Tomaszewski, M., Samani, N. J. and Hengstenberg, C. (2011) Heritability of Early Repolarization: A Population-Based Study. Circulation: Cardiovascular Genetics, 4(2), pp. 134-138. (doi: 10.1161/CIRCGENETICS.110.958298)
Shah, S. et al. (2011) Four genetic loci influencing electrocardiographic indices of left ventricular hypertrophy. Circulation: Cardiovascular Genetics, 4(6), pp. 626-635. (doi: 10.1161/CIRCGENETICS.111.960203)
Sosnowski, M., Macfarlane, P.W. and Tendera, M. (2011) Determinants of a reduced heart rate variability in chronic atrial fibrillation. Annals of Noninvasive Electrocardiology, 16(4), pp. 321-326. (doi: 10.1111/j.1542-474X.2011.00458.x)
Surawicz, B. and Macfarlane, P.W. (2011) Inappropriate and Confusing Electrocardiographic Terms. Journal of the American College of Cardiology, 57(15), pp. 1584-1586. (doi: 10.1016/j.jacc.2010.11.040)
2010
Caslake, M.J. et al. (2010) Lipoprotein-associated phospholipase A2 inflammatory biomarkers, and risk of cardiovascular disease in the Prospective Study of Pravastatin in the Elderly at Risk (PROSPER). Atherosclerosis, 210(1), pp. 28-34. (doi: 10.1016/j.atherosclerosis.2009.10.041)
Sattar, N. et al. (2010) Statins and risk of incident diabetes: a collaborative meta-analysis of randomised statin trials. Lancet, 375(9716), pp. 735-742. (doi: 10.1016/S0140-6736(09)61965-6)
Trompet, S. et al. (2010) Pravastatin and cognitive function in the elderly. Results of the PROSPER study. Journal of Neurology, 257(1), pp. 85-90. (doi: 10.1007/s00415-009-5271-7)
Welsh, P. et al. (2010) Unraveling the directional link between adiposity and inflammation: a bidirectional mendelian randomization approach. Journal of Clinical Endocrinology and Metabolism, 95(1), pp. 93-99. (doi: 10.1210/jc.2009-1064)
Batchvarov, V. N., Govindan, M., Macfarlane, P., Camm, A. J. and Behr, E. R. (2010) Diagnostic utility of bipolar precordial leads during ajmaline testing for suspected Brugada syndrome. Heart Rhythm, 7(2), pp. 208-215. (doi: 10.1016/j.hrthm.2009.10.005)
Clark, E.N., Sejersten, M., Clemmensen, P. and Macfarlane, P.W. (2010) Automated electrocardiogram interpretation programs versus cardiologists' triage decision making based on teletransmitted data in patients with suspected acute coronary syndrome. American Journal of Cardiology, 106(12), pp. 1696-1702. (doi: 10.1016/j.amjcard.2010.07.047)
Katibi, I., Clark, E., Devine, B., Lloyd, S. and Macfarlane, P.W. (2010) Comparison of QRS duration in African blacks and European caucasians. Computing in Cardiology, 37, pp. 701-704.
Preiss, D. , Welsh, P. , Murray, H., Shepherd, J., Packard, C. , Macfarlane, P., Cobbe, S., Ford, I. and Sattar, N. (2010) Fasting plasma glucose in non-diabetic participants and the risk for incident cardiovascular events, diabetes, and mortality: results from WOSCOPS 15-year follow-up(dagger). European Heart Journal, 31(10), pp. 1230-1236. (doi: 10.1093/eurheartj/ehq095)
2009
Welsh, P. et al. (2009) Leptin Predicts Diabetes but Not Cardiovascular Disease Results from a large prospective study in an elderly population. Diabetes Care, 32(2), pp. 308-310. (doi: 10.2337/dc08-1458)
Macfarlane, P. (2009) The International Society of Electrocardiology. Journal of Electrocardiology, 42(3), pp. 221-222.
Sattar, N.A. et al. (2009) Are markers of inflammation more strongly associated with risk for fatal than for nonfatal vascular events? PLoS Medicine, 6(6), e1000099. (doi: 10.1371/journal.pmed.1000099)
Sattar, N. et al. (2009) Are elevated circulating intercellular adhesion molecule 1 levels more strongly predictive of diabetes than vascular risk? Outcome of a prospective study in the elderly. Diabetologia, 52(2), pp. 235-239.
2008
Sattar, N. et al. (2008) Can metabolic syndrome usefully predict cardiovascular disease and diabetes? Outcome data from two prospective studies. Lancet, 371(9628), pp. 1927-1935. (doi: 10.1016/S0140-6736(08)60602-9)
Downs, J.R. et al. (2008) Efficacy of cholesterol-lowering therapy in 18 686 people with diabetes in 14 randomised trials of statins: a meta-analysis. Lancet, 371(9607), pp. 117-125. (doi: 10.1016/S0140-6736(08)60104-X)
Belch, J. et al. (2008) The prevention of progression of arterial disease and diabetes (POPADAD) trial: factorial randomised placebo controlled trial of aspirin and antioxidants in patients with diabetes and asymptomatic peripheral arterial disease. British Medical Journal, 337, a1840. (doi: 10.1136/bmj.a1840)
Cooper, C., Clark, E. and Macfarlane, P. (2008) Enhanced Detection of Electrode Placement/Connection Errors. In: Computers in Cardiology. IEEE: New York, pp. 89-92. ISBN 978-1-4244-3706-1
De Ruijter, W., Assendelft, W., Macfarlane, P., Westendorp, R. and Gussekloo, J. (2008) The additional value of routine electrocardiograms in cardiovascular risk management of older people - The Leiden 85-plus Study: An observational, prospective cohort study. Scandinavian Journal of Primary Health Care, 26(3), pp. 147-153. (doi: 10.1080/02813430802095812)
Sohaib, S., Papacosta, O., Morris, R., Macfarlane, P. and Whincup, P. (2008) Length of the QT interval: determinants and prognostic implications in a population-based prospective study of older men. Journal of Electrocardiology, 41(6), pp. 704-710.
Trompet, S. et al. (2008) Lymphotoxin-alpha C804A polymorphism is a risk factor for stroke. The PROSPER study. Experimental Gerontology, 43(8), pp. 801-805. (doi: 10.1016/j.exger.2008.04.006)
Trompet, S. et al. (2008) Genetic variation in the interleukin-1 beta-converting enzyme associates with cognitive function. The PROSPER study. Brain, 131(4), pp. 1069-1077. (doi: 10.1093/brain/awn023)
2007
Packard, C.J. et al. (2007) Association between apolipoprotein E4 and cognitive decline in elderly adults. Journal of the American Geriatrics Society, 55(11), pp. 1777-1785. (doi: 10.1111/j.1532-5415.2007.01415.x)
Sattar, N. , McConnachie, A. , Ford, I. , Gaw, A., Cleland, S.J., Forouhi, N.G., Macfarlane, P., Shepherd, J., Cobbe, S. and Packard, C. (2007) Serial metabolic measurements and conversion to type 2 diabetes in the West of Scotland Coronary Prevention Study - Specific elevations in alanine aminotransferase and triglycerides suggest hepatic fat accumulation as a potential contributing factor. Diabetes, 56(4), pp. 984-991. (doi: 10.2337/db06-1256)
Barber, M., Barlow, N., Macfarlane, P., Morton, J., Roditi, G. and Stott, D. (2007) Elevated troponin levels are associated with sympathoadrenal activation in acute ischaemic stroke. Cerebrovascular Diseases, 23, pp. 260-266. (doi: 10.1159/000098325)
Barber, M., Morton, J., Macfarlane, P., Barlow, N., Roditi, G. and Stott, D. (2007) Elevated troponin levels are associated with sympathoadrenal activation in acute ischaemic stroke. Cerebrovascular Diseases, 23, pp. 260-266.
Clark, E., Macfarlane, P.W., McGavigan, A.D., Quinn, R. and Rankin, A.C. (2007) Localization of accessory pathways in the Wolff-Parkinson-White pattern - Physician versus computer interpretation of the same algorithm. Pacing and Clinical Electrophysiology, 30, pp. 998-1002.
de Ruijter, W., Westendorp, R., Macfarlane, P., Jukema, J., Assendelft, W. and Gussekloo, J. (2007) The routine electrocardiogram for cardiovascular risk stratification in old age: The Leiden 85 plus Study. Journal of the American Geriatrics Society, 55, pp. 872-877.
de Ruijter, W., Westendorp, R., Macfarlane, P., Jukema, J., Assendelft, W. and Gussekloo, J. (2007) The routine electrocardiogram for cardiovascular risk stratification in old age: The leiden 85-plus study. Journal of the American Geriatrics Society, 55, pp. 872-877. (doi: 10.1111/j.1532-5415.2007.01180.x)
Fayn, J., Rubel, P. and Macfarlane, P. (2007) Can the lessons learned from the assessment of automated electrocardiogram analysis in the common standards for quantitative Electrocardiography study benefit measurement of delayed contrast-enhanced magnetic reasonance images? Journal of Electrocardiology, 40, pp. 872-877.
Ford, I., Murray, H., Shepherd, J., Packard, C. , Macfarlane, P. and Cobbe, S. (2007) Long-term follow-up of the West of Scotland Coronary Prevention Study. New England Journal of Medicine, 357(15), pp. 1477-1486. (doi: 10.1056/NEJMoa065994)
Kligfield, P. et al. (2007) Guidelines for the standardization and interpretation of the electrocardiogram, Part 1: The electrocardiogram and its technology. Circulation, 115, pp. 1306-1324.
Macfarlane, P. (2007) The Pierre Rijlant Lecture 2007: The Future of Elecctrocardiology. Anatolian Journal of Cardiology, 7(Suppl), pp. 1-4.
Macfarlane, P. (2007) Update on ACC/ESC criteria for acute ST elevation myocardial infarction in : Gulizia M,M.(ed). Current News in Cardiology, pp. 341-345.
Macfarlane, P., Hampton, D., Clark, E., Devine, B. and Jayne, C. (2007) Computer analysis of implanted Cardiac Pacemaker Rhythm. Computers in Cardiology, 34, pp. 293-296.
Macfarlane, P., Hampton, D., Clark, E., Devine, B. and Jayne, C. (2007) Evaluation of Age and Sex Dependent Criteria for ST Elevation Myocardial Infarction. Computers in Cardiology, 34, pp. 293-296.
Macfarlane, P. and Norrie, J. (2007) The value of the electrocardiogram in risk assessment in primary prevention: Experience from the West of Scotland Coronary Prevention Study. Journal of Electrocardiology, 40, pp. 101-109. (doi: 10.1016/j.jelectrocard.2006.05.003)
Macfarlane, P. and Norrie, J. (2007) The value of the electrocardiogram in risk assessment in primary prevention: Experience from the West of Scotland Coronary Prevention Study. Journal of Electrocardiology, 40, pp. 101-109.
McGavigan, A., Clark, E., Quinn, R., Rankin, A. and Macfarlane, P. (2007) Localization of accessory pathways in the Wolff-Parkinson-White pattern - Physician versus computer interpretation of the same algorithm. Pacing and Clinical Electrophysiology, 30, pp. 998-1002.
Sattar, N. et al. (2007) C-reactive protein and prediction of coronary heart disease and global vascular events in the prospective study of pravastatin in the elderly at risk (PROSPER). Circulation, 115(8), pp. 981-989. (doi: 10.1161/CIRCULATIONAHA.106.643114)
Trompet, S. et al. (2007) Genetic variation in the interleukin-10 gene promoter and risk of coronary and cerebrovascular events: the PROSPER Study. Annals of the New York Academy of Sciences, 1100, pp. 189-198.
Trompet, S. et al. (2007) Genetic variation in the interleukin-10 gene promoter and risk of coronary and cerebrovascular events - The PROSPER study. In: Rattan, S. and Akman, S. (eds.) Biogerontology: Mechanisms and Interventions. Series: Annals of the New York Academy of Sciences (1100). Blackwell Publishing: Oxford, pp. 189-198. ISBN 978-1-57331-679-8 (doi: 10.1196/annals.1395.018)
2006
Clark, E., Cleland, J., Gemmell, I., Khand, A., Macfarlane, P. and Rankin, A. (2006) The assessment of autonomic function in chronic atrial fibrillation: description of a non-invasive technique based on circadian rhythm of atrioventricular nodal functional refractory periods. Europace, 8, pp. 927-934. (doi: 10.1093/europace/eul111)
Clark, E., Devine, B. and Macfarlane, P. (2006) Age and Sex Dependent Criteria for Lower Limits of QRS Voltages. Computers in Cardiology, 33, pp. 81-84.
Gordon, M. et al. (2006) A means to an endpoint. Good Clinical Practice Journal, 13(10), pp. 25-29.
Gordon, M. et al. (2006) A means to an endpoint. Good Clinical Practice Journal, 13(10), pp. 25-29.
Khand, A., Rankin, A., Cleland, J., Gemmell, I., Clark, E. and Macfarlane, P. (2006) The assessment of autonomic function in chronic atrial fibrillation: description of a non-invasive technique based on circadian rhythm of atrioventricular nodal functional refractory periods. Europace, 8, pp. 927-934.
Macfarlane, P. (2006) Is electrocardiography still useful in the diagnosis of cardiac chamber hypertrophy and dilatation? Cardiology Clinics, 24, 401-+. (doi: 10.1016/j.ccl.2006.04.013)
Sosnowski, M., Macfarlane, P., Parma, R., Skrzypek-Wanha, J. and Tendera, M. (2006) Prognostic Value of Heart Rate Variability Analysis in Patients with Depressed Left Ventricular Function Irrespective of Cardiac Rhythm. Computers in Cardiology, 33, pp. 81-84.
van Bemmel, T., Vinkers, D., Macfarlane, P., Gussekloo, J. and Westendorp, R. (2006) Markers of autonomic tone on a standard ECG are predictive of mortality in old age. International Journal of Cardiology, 107, pp. 36-41. (doi: 10.1016/j.ijcard.2005.02.031)
van Bemmel, T., Vinkers, D., Macfarlane, P., Gussekloo, J. and Westendorp, R. (2006) Markers of autonomic tone on a standard ECG are predictive of mortality in old age. International Journal of Cardiology, 107, pp. 36-41.
Verluis, C. et al. (2006) Progression of cerebral white matter lesions is not associated with development of depressive symptoms in elderly subjects at risk of cardiovascular disease. The PROSPER Study. International Journal of Geriatric Psychiatry, 21(4), pp. 375-381.
Wagner, G. et al. (2006) Consideration of pitfalls in and omissions from the current ECG Standards for diagnosis of Myocardial Ischemia/Infarction in patients who have Acute Coronary Syndromes. Cardiology Clinics, 24, pp. 331-342.
2005
Stott, D. J. et al. (2005) Randomized controlled trial of homocysteine-lowering vitamin treatment in elderly patients with vascular disease. American Journal of Clinical Nutrition, 82(6), pp. 1320-1326. (doi: 10.1093/ajcn/82.6.1320) (PMID:16332666)
Bootsma-van der Wiel, A., de Craen, A. J.M., van Exel, E., Macfarlane, P. W., Gussekloo, J. and Westendorp, R. G.J. (2005) Association between chronic diseases and disability in elderly subjects with low and high income: the Leiden 85-plus study. European Journal of Public Health, 15(5), pp. 494-497. (doi: 10.1093/eurpub/cki015) (PMID:16014663)
Hamilton, R.M., McLeod, K., Houston, A.B. and Macfarlane, P.W. (2005) Inter and Intraobserver Variability in LVH and RVH Reporting in Paediatric ECGs. Annals of Noninvasive Electrocardiology, 10(3), pp. 330-333.
Hamilton, R., Houston, A., McLeod, K. and Macfarlane, P. (2005) Evaluation of paediatric electrocardiogram diagnosis of ventricular hypertrophy by computer program compared with cardiologists. Paediatric Cardiology, 26, pp. 373-378.
Hamilton, R., Houston, A., McLeod, K. and Macfarlane, P. (2005) Evaluation of pediatric electrocardiogram diagnosis of ventricular hypertrophy by computer program compared with cardiologists. Pediatric Cardiology, 26, pp. 373-378. (doi: 10.1007/s00246-004-0748-8)
Hamilton, R., McLeod, K., Houston, A. and Macfarlane, P. (2005) Inter- and intraobserver variability in LVH and RVH reporting in pediatric ECGs. Annals of Noninvasive Electrocardiology, 10, pp. 330-333.
Macfarlane, P., Devine, B. and Clark, E. (2005) The University of Glasgow (Uni-G) ECG Analysis Program. Computers in Cardiology, 32, pp. 451-454.
Macfarlane, P., Rubel, P. and van Bemmel, J. (2005) Christoph Zywietz 1937-2005 - In memoriam. Journal of Electrocardiology, 38, pp. 404-405.
Madias, J.E. and MacFarlane, P.W. (2005) Artificial attenuation of ECG voltage produces shortening of the corresponding QRS duration: Clinical implications for patients with edema. Pacing and Clinical Electrophysiology, 28, pp. 1060-1065.
Packard, C.J. et al. (2005) Plasma lipoproteins and apolipoproteins as predictors of cardiovascular risk and treatment benefit in the PROspective Study of Pravastatin in the Elderly at Risk (PROSPER). Circulation, 112, pp. 3058-3065. (doi: 10.1161/CIRCULATIONAHA.105.526848)
Sosnowski, M., Clark, E., Latif, S., Macfarlane, P.W. and Tendera, M. (2005) Heart rate variability fraction - a new reportable measure of 24-hour R-R interval variation. Annals of Noninvasive Electrocardiology, 10, pp. 7-15. (doi: 10.1111/j.1542-474X.2005.00579.x)
2004
Drew, B., Califf, R., Funk, M., Kaufman, E., Krucoff, M., Laks, M., Macfarlane, P., Sommargren, C., Swiryn, S. and Van Hare, G. (2004) Practice standards for electrocardiographic monitoring in hospital settings. Circulation, 110, pp. 2721-2746.
Hamilton, R., Mckechnie, P. and Macfarlane, P. (2004) Can cardiac vagal tone be estimated from the 10-second ECG? International Journal of Cardiology, 95, pp. 109-115. (doi: 10.1016/j.ijcard.2003.07.002)
Hamilton, R., McKechnie, P. and Macfarlane, P. (2004) Can cardiac vagal tone by estimated from the 10-second ECG? International Journal of Cardiology, 95, pp. 109-115.
Hodgart, E. and Macfarlane, P. (2004) 10 Second Heart Rate Variability. Computers in Cardiology, 31, pp. 217-220.
Kumar, R., Fisher, M. and Macfarlane, P. (2004) Diabetes and the QT interval: time for debate. British Journal of Diabetes and Vascular Disease, 4, pp. 146-150.
Kumar, R., Fisher, M., Whitaker, R. and Macfarlane, P. (2004) Effect of controlling hyperglycemia with diet on QT abnormalities in newly diagnosed patients with type 2 diabetes. Diabetes Care, 27, pp. 2767-2768.
Ledmyr, H., McMahon, A., Ehrenborg, E., Nielsen, L., Neville, M., Litchell, H., Macfarlane, P., Packard, C. and Karpe, F. (2004) The microsomal triglyceride transfer protein gene-493T variant lowers cholesterol but increases the risk of coronary heart disease. Circulation, 109, pp. 2279-2284.
Ledmyr, H., McMahon, A. , Ehrenborg, E., Nielsen, L., Neville, M., Lithell, H., MacFarlane, P., Packard, C. and Karpe, F. (2004) The microsomal triglyceride transfer protein gene-493T variant lowers cholesterol but increases the risk of coronary heart disease. Circulation, 109, pp. 2279-2284. (doi: 10.1161/01.CIR.0000130070.96758.7b)
Luo, S., Michler, K., Johnston, P. and Macfarlane, P. (2004) A comparison of commonly used QT correction formulae: The effect of heart rate on the QTc of normal ECGs. Journal of Electrocardiology, 37, pp. 81-90. (doi: 10.1016/j.jelectrocard.2003.08.030)
Macfarlane, P., Browne, D., Devine, B., Clark, E., Miller, E., Seyal, J. and Hampton, D. (2004) Effect of age and gender on diagnostic accuracy of ECG diagnosis of Acute Myocardial Infarction. Computers in Cardiology, 31, pp. 165-168.
Macfarlane, P., Browne, D., Devine, B., Clark, E., Miller, E., Seyal, J. and Hampton, D. (2004) Modification of ACC/ESC criteria for acute myocardial infarction. Journal of Electrocardiology, 37, pp. 98-103. (doi: 10.1016/j.jelectrocard.2004.08.032)
Macfarlane, P., Browne, D., Devine, B., Clark, E., Miller, E., Seyal, J. and Hampton, D. (2004) Modification of ACC/ESC criteria for acute myocardial infarction. Journal of Electrocardiology, 37((Suppl), pp. 98-103.
Macfarlane, P. and Norrie, J. (2004) Looking for prognostic information in the ST-T segment - Is it really worth it? Journal of Electrocardiology, 37, pp. 209-213.
Padmanabhan, S. , Connell, J.M.C., Dominiczak, A.F. , Inglis, G., Macfarlane, P.W. and Watt, G. (2004) Heritability and genetic determinants of electrocardiographic measures of left ventricular mass - a two generation family study. Journal of Hypertension: Supplement, 22(S1), S180-S181.
Petelenz, M., Conciarz, M., Macfarlane, P., Rudner, R., Kawecki, P., Musialik, J., Jalowiecki, P. and Gonciarz, Z. (2004) Sympathovagal balance fluctuates during colonoscopy. Endoscopy, 36, pp. 508-514.
Petelenz, M., Gonciarz, M., Macfarlane, P., Rudner, R., Kawecki, P., Musialik, J., Jalowiecki, P. and Gonciarz, Z. (2004) Sympathovagal balance fluctuates during colonoscopy. Endoscopy, 36, pp. 508-514. (doi: 10.1055/s-2004-814402)
Sattar, N. et al. (2004) Metabolic syndrome and diabetes mellitus - Response. Circulation, 109, E23-E23.
Sattar, N., Scherbakova, O., Ford, I., O'Reilly, D., Stanley, A., Forrest, E., MacFarlane, P., Packard, C. , Cobbe, S. and Shepherd, J. (2004) Elevated alanine aminotransferase predicts new-onset type 2 diabetes independently of classical risk factors, metabolic syndrome, and C-reactive protein in the West of Scotland Coronary Prevention Study. Diabetes, 53(11), pp. 2855-2860. (doi: 10.2337/diabetes.53.11.2855)
Sattar, N., Scherbakova, O., Ford, I., O'Reilly, D., Stanley, A., Forrest, E., Macfarlane, P., Packard, C. and Shepherd, J. (2004) Elevated alanine aminotransferase predicts new-onset type 2 diabetes independently of classical risk factors, metabolic syndrome and C-reactive protein in the West of Scotland Coronary Prevention Study. Diabetes, 53, pp. 2855-2860.
2003
Corlan, A.D., Macfarlane, P.W. and De Ambroggi, L. (2003) Gender differences in stability of the instantaneous patterns of body surface potentials during ventricular repolarisation. Medical and Biological Engineering and Computing, 41(5), pp. 536-542. (doi: 10.1007/BF02345315)
Sattar, N. et al. (2003) Metabolic syndrome with and without C-reactive protein as a predictor of coronary heart disease and diabetes in the West of Scotland Coronary Prevention Study. Circulation, 108(4), pp. 414-419. (doi: 10.1161/01.CIR.0000080897.52664.94) (PMID:12860911)
Cleland, J.G.F. , Pennell, D.J., Ray, S.G., Coats, A.J., Macfarlane, P.W., Murray, G.D., Mule, J.D., Vered, Z. and Lahiri, A. (2003) Myocardial viability as a determinant of the ejection fraction response to Carvedilol in patients with heart failure (CHRISTMAS trial): randomised controlled trial. Lancet, 362(9377), pp. 14-21. (doi: 10.1016/S0140-6736(03)13801-9) (PMID:12853194)
de Craen, A.J.M., Gussekloo, J., Teng, Y.K., Macfarlane, P.W. and Westendorp, R.G.J. (2003) Prevalence of five common clinical abnormalities in very elderly people: population based cross sectional study. British Medical Journal, 327(7407), pp. 131-132. (doi: 10.1136/bmj.327.7407.131)
Hemingway, H., Shipley, M., Britton, A., Page, M., Macfarlane, P. and Marmot, M. (2003) Prognosis of angina with and without a diagnosis: 11 year follow up in the Whitehall II prospective cohort study. British Medical Journal, 327, pp. 895-898.
Huwez, F. and Macfarlane, P. (2003) Assessment of selected ECG voltage criteria for abnormality in eccentric and concentric left ventricular hypertrophy. Computers in Cardiology, 30, pp. 57-59.
Huwez, F. and Macfarlane, P. (2003) The influence of Q wave acute anteroseptal myocardial infarction on the voltage criteria for left ventricular hypertrophy. Computers in Cardiology, 30, pp. 815-818.
Macfarlane, P. (2003) The History of the International Society of Electrocardiology. International Journal of Bioelectromagnetism, 5(1), pp. 36-41.
Macfarlane, P., Colaco, R., Stevens, K., Reay, P., Beckett, C. and Aitchison, T. (2003) Precordial electrode placement in women. Netherlands Heart Journal, 11, pp. 118-122.
Oberstein, S., Jukema, J., van Duinen, S., Macfarlane, P., van Howelingen, H., Breuning, M., Ferrari, M. and Haan, J. (2003) Myocardial infarction in cerebral autosomal dominant Arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL). Medicine, 82, pp. 251-256.
Paracha, M., Mohammad, S., Macfarlane, P. and Jenkins, J. (2003) Implementation of Web Database for ECG. Computers in Cardiology, 30, pp. 271-274.
Paracha, M., Mohammad, S., Macfarlane, P. and Jenkins, J. (2003) Real-time custom processing and delivery of large ECG data sets. Computers in Cardiology, 30, pp. 411-412.
van Exel, E. et al. (2003) Interaction of atherosclerosis and inflammation in elderly subjects with poor cognitive function. Neurology, 61, pp. 1695-1701.
2002
Ford, I. et al. (2002) A prospective study of pravastatin in the elderly at risk (PROSPER): Screening experience and baseline characteristics. Current Controlled Trials in Cardiovascular Medicine, 3, p. 8. (doi: 10.1186/1468-6708-3-8)
Houx, P.J. et al. (2002) Testing cognitive function in elderly populations: the PROSPER study. Journal of Neurology, Neurosurgery and Psychiatry, 73(4), pp. 385-389. (doi: 10.1136/jnnp.73.4.385)
Macfarlane, P. (2002) Gender dependent normal limits of ST-T amplitudes. International Journal of Bioelectromagnetism, 4, pp. 37-39.
McKechnie, P., Hamilton, R. and Macfarlane, P. (2002) Exercise levels predict cardiac vagal tone as measured by the Neuroscope. International Journal of Bioelectromagnetism, 4, pp. 309-310.
Robertson, A., Clark, E., van Oosterom, A. and Macfarlane, P. (2002) ECG monitoring using a limited lead set. International Journal of Bioelectromagnetism, 4, pp. 295-298.
Sattar, N., Macfarlane, P., Packard, C., Kelly, A., Shepherd, J., Gaw, A., Wallace, A. and McMahon, A. (2002) Plasma leptin levels and coronary heart disease - Response. Circulation, 106, E42-E42.
Seyal, J., Clark, E. and Macfarlane, P. (2002) Diagnosis of acute myocardial ischaemia using probabilistic methods. Journal of Cardiovascular Risk, 9(2), pp. 115-121.
Seyal, J., Clark, E. and Macfarlane, P. (2002) Diagnosis of acute myocardial ischaemia using probabilistic methods. Journal of Cardiovascular Risk, 9, pp. 115-121.
Shepherd, J. et al. (2002) Pravastatin in elderly individuals at risk of vascular disease (PROSPER): a randomised controlled trial. Lancet, 360(9346), pp. 1623-1630. (doi: 10.1016/S0140-6736(02)11600-X)
Shepherd, J. et al. (2002) Pravastatin in elderly individuals at risk of vascular disease (PROSPER) at randomised controlled trial. Lancet, 360(9346), pp. 1623-1630.
Sosnowski, M., MacFarlane, P., Czyz, Z., Skrzypek-Wanha, J., Boczkowska-Gaika, E. and Tendera, M. (2002) Age-adjustment of HRV measures and its prognostic value for risk assessment in patients late after myocardial infarction. International Journal of Cardiology, 86, pp. 249-258.
van Exel, E., de Craen, A., Gussekloo, J., Houx, P., Bootsma-van der Wiel, A. and Macfarlane, P. (2002) Association between high-density lipoprotein and cognitive impairment in the oldest old. Annals of Neurology, 51, pp. 716-721.
van Exel, E., Gussekloo, J., Houx, P., de Craen, A., Macfarlane, P., Bootsma-van der Wiel, A., Blauw, G. and Westendorp, R. (2002) Atherosclerosis and cognitive impairment are linked in the elderly. The Leiden 85-plus Study. Atherosclerosis, 165, pp. 353-359.
van Exel, E., Gussekloo, J., Houx, P., de Craen, A., Macfarlane, P., Bootsma-van der Wiel, A., Blauw, G. and Westendorp, R. (2002) Atherosclerosis and cognitive impairment are linked in the elderly. The Leiden 85-plus study. Atherosclerosis, 165, pp. 353-359.
2001
Anderston, S. et al. (2001) Standards for the function of an academic 12-lead electrocardiographic core laboratory. Journal of Electrocardiology, 34, pp. 41-47.
Ford, I., McMahon, A., Pell, J., Packard, C., Macfarlane, P., Cobbe, S. and Shepherd, J. (2001) The prognostic value for stroke of a nurse-led screening assessment of 71,527 Scottish middle-aged men. Journal of the American College of Cardiology, 37, 226A.
Freeman, D. et al. (2001) Do statins reduce the risk for diabetes by improving exercise capacity? Response. Circulation, 104, E104-E105.
Freeman, D. et al. (2001) Pravastatin and the development of Diabetes Mellitus. Evidence for a Protective Treatment Effect in the West of Scotland Coronary Prevention Study. Circulation, 103, pp. 357-362.
Freeman, D. et al. (2001) Pravastatin and the development of diabetes mellitus - Evidence for a protective treatment effect in the West of Scotland Coronary Prevention Study. Circulation, 103(3), pp. 357-362.
Jacobsen, J., Wagner, G., Holmvang, L., Macfarlane, P., Naslund, U., Grande, P. and Clemmensen, P. (2001) Clinical significance of abnormal T waves in patients with non-ST-segment elevation acute coronary syndromes. American Journal of Cardiology, 88, pp. 1225-1229.
Jacobsen, M., Wagner, G., Holmvang, L., Macfarlane, P., Naslund, U., Grande, P., Clemmensen, P. and TRIM Investigators, (2001) Clinical significance of abnormal T waves in patients with non-ST-segment elevation acute coronary syndromes. American Journal of Cardiology, 88, pp. 1225-1229.
Macfarlane, P. (2001) Age, sex and the ST amplitude in Health and Disease. Journal of Electrocardiology, 34((Suppl), pp. 235-241.
Macfarlane, P. (2001) Age, sex, and the ST amplitude in health and disease. Journal of Electrocardiology, 34, pp. 235-241.
Mamode, N., Docherty, G., Lowe, G.D.O., Macfarlane, P.W., Martin, W., Pollock, J.G. and Cobbe, S.M. (2001) The role of myocardial perfusion scanning, heart rate variability and D-dimers in predicting the risk of perioperative cardiac complications after peripheral vascular surgery. European Journal of Vascular and Endovascular Surgery, 22(6), pp. 499-508. (doi: 10.1053/ejvs.2001.1529)
Murray, P., Hamilton, R. and Macfarlane, P. (2001) Reproducibility of a non-invasive real-time measure of cardiac parasympathetic activity. Physiological Measurement, 22, pp. 661-672.
Murray, P., Hamilton, R. and Macfarlane, P. (2001) Reproducibility of a non-invasive real-time measure of cardiac parasympathetic activity. Physiological Measurement, 22, pp. 661-672.
2000
Morrison, S. and Macfarlane, P.W. (2000) Computer detection of atrial flutter. Annals of Noninvasive Electrocardiology, 5(4), pp. 358-364. (doi: 10.1111/j.1542-474X.2000.tb00074.x)
Calaco, R., Reay, P., Beckett, C., Aitchison, T. and Macfarlane, P. (2000) False positive ECG reports of anterior myocardial infarction in women. Journal of Electrocardiology, 33((Suppl), pp. 239-244.
Clark, L., Watson, J., Cobbe, S., Reeve, W., Swann, I. and Macfarlane, P. (2000) CPR '98: A practical multimedia computer-based guide to cardiopulmonary resuscitation for medical students. Resuscitation, 44, pp. 109-117.
Lowe, G., Rumley, A., Norrie, J., Ford, I. , Shepherd, J., Cobbe, S., Macfarlane, P. and Packard, C. (2000) Blood rheology, cardiovascular risk factors, and cardiovascular disease: The West of Scotland Coronary Prevention Study. Thrombosis and Haemostasis, 84(4), pp. 553-558.
Macfarlane, P. (2000) Minnesota coding and prevalence of ECG abnormalities. Heart, 84(6), pp. 582-584.
1995
Shepherd, J., Cobbe, S.M., Ford, I. , Isles, C.G., Lorimer, A.R., Macfarlane, P.W., McKillop, J.H. and Packard, C.J. (1995) Prevention of coronary heart disease with pravastatin in men with hypercholesterolemia. New England Journal of Medicine, 333(20), pp. 1301-1308. (doi: 10.1056/NEJM199511163332001)
Articles
Porr, B. and Macfarlane, P. W. (2024) A new QRS detector stress test combining temporal jitter and F-score (JF) reveals significant performance differences amongst popular detectors. PLoS ONE, 19(11), e0309739. (doi: 10.1371/journal.pone.0309739) (PMID:39527567) (PMCID:PMC11554035)
Morrow, A. et al. (2024) Zibotentan in microvascular angina: a randomized, placebo-controlled, crossover trial. Circulation, (doi: 10.1161/CIRCULATIONAHA.124.069901) (PMID:39217504) (Early Online Publication)
Ensam, B. et al. (2024) Type 1 Brugada pattern may be provoked by ajmaline in some healthy subjects: results from a clinical trial. Circulation, 149(21), pp. 1693-1695. (doi: 10.1161/circulationaha.123.067223) (PMID:38768273) (PMCID:PMC11115450)
Joy, G. et al. (2024) Electrophysiological characterization of subclinical and overt hypertrophic cardiomyopathy by magnetic resonance imaging-guided electrocardiography. Journal of the American College of Cardiology, 83(11), pp. 1042-1055. (doi: 10.1016/j.jacc.2024.01.006) (PMID:38385929) (PMCID:PMC10945386)
Morrow, A. J. et al. (2024) Socioeconomic deprivation and illness trajectory in the Scottish population after COVID-19 hospitalization. Communications Medicine, 4, 32. (doi: 10.1038/s43856-024-00455-5) (PMID:38418616) (PMCID:PMC10901805)
Berry, C. et al. (2023) Mental health symptoms and illness trajectory following COVID-19 hospitalization: A cohort study. Heart and Mind, 7(4), pp. 235-245. (doi: 10.4103/hm.HM-D-23-00037)
Joy, G. et al. (2023) Microstructural and microvascular phenotype of sarcomere mutation carriers and overt hypertrophic cardiomyopathy. Circulation, 148(10), pp. 808-818. (doi: 10.1161/circulationaha.123.063835) (PMID:37463608) (PMCID:PMC10473031)
van de Vegte, Y. J. et al. (2023) Genetic insights into resting heart rate and its role in cardiovascular disease. Nature Communications, 14(1), 4646. (doi: 10.1038/s41467-023-39521-2) (PMID:37532724) (PMCID:PMC10397318)
Young, W. J. et al. (2023) Genetic architecture of spatial electrical biomarkers for cardiac arrhythmia and relationship with cardiovascular disease. Nature Communications, 14, 1411. (doi: 10.1038/s41467-023-36997-w) (PMID:36918541) (PMCID:PMC10015012)
Artico, J. et al. (2023) Myocardial involvement after hospitalization for COVID-19 complicated by troponin elevation: a prospective, multicenter, observational study. Circulation, 147(5), pp. 364-374. (doi: 10.1161/CIRCULATIONAHA.122.060632) (PMID:36705028) (PMCID:PMC9889203)
Sykes, R. et al. (2023) Adjudicated myocarditis and multisystem illness trajectory in healthcare workers post-COVID-19. Open Heart, 10(1), e002192. (doi: 10.1136/openhrt-2022-002192) (PMID:36822817) (PMCID:PMC9950584)
Brandes, A. et al. (2022) Consumer-led screening for atrial fibrillation: Frontier review of the AF-SCREEN International Collaboration. Circulation, 146(19), pp. 1461-1474. (doi: 10.1161/circulationaha.121.058911) (PMID:36343103)
Young, W. J. et al. (2022) Genetic analyses of the electrocardiographic QT interval and its components identify additional loci and pathways. Nature Communications, 13, 5144. (doi: 10.1038/s41467-022-32821-z) (PMID:36050321) (PMCID:PMC9436946)
Al-Zaiti, S. S., Alghwiri, A. A., Hu, X., Clermont, G., Peace, A., Macfarlane, P. and Bond, R. (2022) A clinician’s guide to understanding and critically appraising machine learning studies: a checklist for Ruling Out Bias Using Standard Tools in Machine Learning (ROBUST-ML). European Heart Journal: Digital Health, 3(2), pp. 125-140. (doi: 10.1093/ehjdh/ztac016) (PMID:36713011) (PMCID:PMC9708024)
Morrow, A. J. et al. (2022) A multisystem, cardio-renal investigation of post-COVID-19 illness. Nature Medicine, 28(6), pp. 1303-1313. (doi: 10.1038/s41591-022-01837-9) (PMID:35606551) (PMCID:PMC9205780)
Siland, J. E. et al. (2022) Resting heart rate and incident atrial fibrillation: A stratified Mendelian randomization in the AFGen consortium. PLoS ONE, 17(5), e0268768. (doi: 10.1371/journal.pone.0268768) (PMID:35594314) (PMCID:PMC9122202)
de Groot, N. M.S. et al. (2022) Critical appraisal of technologies to assess electrical activity during atrial fibrillation: a position paper from the European Heart Rhythm Association and European Society of Cardiology Working Group on eCardiology in collaboration with the Heart Rhythm Society, Asia Pacific Heart Rhythm Society, Latin American Heart Rhythm Society and Computing in Cardiology. Europace, 24(2), pp. 313-330. (doi: 10.1093/europace/euab254) (PMID:34878119)
Macfarlane, P. W. (2022) The application of computer techniques to ECG interpretation. Hearts, 3(1), pp. 1-5. (doi: 10.3390/hearts3010001)
Macfarlane, P. W. and Kennedy, J. (2021) Automated ECG interpretation—a brief history from high expectations to deepest networks. Hearts, 2(4), pp. 433-448. (doi: 10.3390/hearts2040034)
Paixão, G. M. M., Lima, E. M., Gomes, P. R., Oliveira, D. M., Ribeiro, M. H., Nascimento, J. S., Ribeiro, A. H., Macfarlane, P. W. and Ribeiro, A. L. P. (2021) Electrocardiographic predictors of mortality: data from a primary care tele-electrocardiography cohort of Brazilian patients. Hearts, 2(4), pp. 449-458. (doi: 10.3390/hearts2040035)
Berry, C. et al. (2021) Post-COVID-19 illness trajectory: a multisystem investigation [Pre-print]. Research Square, (doi: 10.21203/rs.3.rs-1053331/v1)
Rubel, P., Fayn, J., Macfarlane, P. W., Pani, D., Schlögl, A. and Värri, A. (2021) The history and challenges of SCP-ECG: the standard communication protocol for computer-assisted electrocardiography. Hearts, 2(3), pp. 384-409. (doi: 10.3390/hearts2030031)
Gorecka, M. et al. (2021) Demographic, multi-morbidity and genetic impact on myocardial involvement and its recovery from COVID-19: protocol design of COVID-HEART—a UK, multicentre, observational study. Journal of Cardiovascular Magnetic Resonance, 23, 77. (doi: 10.1186/s12968-021-00752-1) (PMID:34112195) (PMCID:PMC8190746)
Maznyczka, A. M. et al. (2021) Effect of coronary flow on intracoronary alteplase: a prespecified analysis from a randomised trial. Heart, 107(4), pp. 299-312. (doi: 10.1136/heartjnl-2020-317828) (PMID:33436493)
Mangion, K. et al. (2020) The Chief Scientist Office cardiovascular and pulmonary imaging in SARS Coronavirus disease-19 (CISCO-19) study. Cardiovascular Research, 116(14), pp. 2185-2196. (doi: 10.1093/cvr/cvaa209) (PMID:32702087) (PMCID:PMC7454350)
McCartney, P. J. et al. (2020) Low-dose intracoronary alteplase during primary percutaneous coronary intervention in patients with acute myocardial infarction: the T-TIME three-arm RCT. Efficacy and Mechanism Evaluation, 7(5), (doi: 10.3310/eme07050) (PMID:33175484)
Morrow, A. J. et al. (2020) Rationale and design of the Medical Research Council precision medicine with Zibotentan in microvascular angina (PRIZE) trial. American Heart Journal, 229, pp. 70-80. (doi: 10.1016/j.ahj.2020.07.007) (PMID:32942043)
Macfarlane, P. W. (2020) New ECG criteria for acute myocardial infarction in patients with left bundle branch block. Journal of the American Heart Association, 9(14), e017119. (doi: 10.1161/jaha.120.017119) (PMID:32627635)
Ntalla, I. et al. (2020) Multi-ancestry GWAS of the electrocardiographic PR interval identifies 202 loci underlying cardiac conduction. Nature Communications, 11, 2542. (doi: 10.1038/s41467-020-15706-x) (PMID:32439900) (PMCID:PMC7242331)
Ribeiro, A. H. et al. (2020) Automatic diagnosis of the 12-lead ECG using a deep neural network. Nature Communications, 11, 1760. (doi: 10.1038/s41467-020-15432-4) (PMID:32273514) (PMCID:PMC7145824)
Zonneveld, M. H., Noordam, R., Grond, J., Sabayan, B., Mooijaart, S. P., Macfarlane, P. W., Jukema, J. W. and Trompet, S. (2020) Ventricular repolarization is associated with cognitive function, but not with cognitive decline and brain Magnetic Resonance Imaging (MRI) measurements in older adults. Journal of Clinical Medicine, 9(4), e911. (doi: 10.3390/jcm9040911)
Maznyczka, A. M. et al. (2020) Effects of intracoronary alteplase on microvascular function in acute myocardial infarction. Journal of the American Heart Association, 9(3), e014066. (doi: 10.1161/JAHA.119.014066) (PMID:31986989) (PMCID:PMC7033872)
Ribeiro, A. L. P. et al. (2019) Tele-electrocardiography and bigdata: the CODE (Clinical Outcomes in Digital Electrocardiography) study. Journal of Electrocardiology, 57(Suppl), S75-S78. (doi: 10.1016/j.jelectrocard.2019.09.008) (PMID:31526573)
Kitas, G. D. et al. (2019) A multicenter, randomized, placebo‐controlled trial of atorvastatin for the primary prevention of cardiovascular events in patients with rheumatoid arthritis. Arthritis and Rheumatology, 71(9), pp. 1437-1449. (doi: 10.1002/art.40892) (PMID:30983166) (PMCID:PMC6771601)
Walsh, B., Macfarlane, P. W., Prutkin, J. M. and Smith, S. W. (2019) Distinctive ECG patterns in healthy black adults. Journal of Electrocardiology, 56, pp. 15-23. (doi: 10.1016/j.jelectrocard.2019.06.007) (PMID:31229678)
van Setten, J. et al. (2019) Genome-wide association meta-analysis of 30,000 samples identifies seven novel loci for quantitative ECG traits. European Journal of Human Genetics, 27(6), pp. 952-962. (doi: 10.1038/s41431-018-0295-z) (PMID:30679814) (PMCID:PMC6777533)
Armitage, J. et al. (2019) Efficacy and safety of statin therapy in older people: a meta-analysis of individual participant data from 28 randomised controlled trials. Lancet, 393(10170), pp. 407-415. (doi: 10.1016/S0140-6736(18)31942-1) (PMID:30712900) (PMCID:PMC6429627)
Ellervik, C. et al. (2019) Assessment of the relationship between genetic determinants of thyroid function and atrial fibrillation: a Medelian randomization study. JAMA Cardiology, 4(2), pp. 144-152. (doi: 10.1001/jamacardio.2018.4635) (PMID:30673084) (PMCID:PMC6396813)
Mahinrad, S. et al. (2019) Spatial QRS-T angle and cognitive decline in older subjects. Journal of Alzheimer's Disease, 67(1), pp. 279-289. (doi: 10.3233/JAD-180633) (PMID:30584139)
Elffers, T.W., Trompet, S., de Mutsert, R., Maan, A.C., Lamb, H.J., Macfarlane, P.W., Rosendaal, F.R. and Jukema, J.W. (2019) Borderline Q-waves in individuals without overt cardiovascular disease: relations with adiposity, subclinical atherosclerosis and vascular stiffness. International Journal of Cardiology, 274, pp. 331-336. (doi: 10.1016/j.ijcard.2018.08.088) (PMID:30195838)
McCartney, P. J. et al. (2019) Effect of low-dose intracoronary alteplase during primary percutaneous coronary intervention on microvascular obstruction in patients with acute myocardial infarction: a randomized clinical trial. JAMA: Journal of the American Medical Association, 321(1), pp. 56-68. (doi: 10.1001/jama.2018.19802) (PMID:30620371) (PMCID:PMC6583564)
Pulit, S. L. et al. (2018) Atrial fibrillation genetic risk differentiates cardioembolic stroke from other stroke subtypes. Neurology Genetics, 4(6), e293. (doi: 10.1212/NXG.0000000000000293) (PMID:30584597) (PMCID:PMC6283455)
Roselli, C. et al. (2018) Multi-ethnic genome-wide association study for atrial fibrillation. Nature Genetics, 50(9), pp. 1225-1233. (doi: 10.1038/s41588-018-0133-9) (PMID:29892015)
Van Setten, J. et al. (2018) PR interval genome-wide association meta-analysis identifies 50 loci associated with atrial and atrioventricular electrical activity. Nature Communications, 9, 2904. (doi: 10.1038/s41467-018-04766-9) (PMID:30046033) (PMCID:PMC6060178)
Kligfield, P. et al. (2018) Comparison of automated interval measurements by widely used algorithms in digital electrocardiographs. American Heart Journal, 200, pp. 1-10. (doi: 10.1016/j.ahj.2018.02.014)
Seyerle, A. A. et al. (2018) Pharmacogenomics study of thiazide diuretics and QT interval in multi-ethnic populations: the cohorts for heart and aging research in genomic epidemiology. Pharmacogenomics Journal, 18(2), pp. 215-226. (doi: 10.1038/tpj.2017.10) (PMID:28719597) (PMCID:PMC5773415)
Elffers, T. W., de Mutsert, R., Lamb, H. J., Maan, A. C., Macfarlane, P. W., Willems van Dijk, K., Rosendaal, F. R., Jukema, J. W. and Trompet, S. (2018) Relation of overall and abdominal adiposity with electrocardiogram parameters of subclinical cardiovascular disease in individuals aged 45 to 65 years (from the Netherlands Epidemiology of Obesity Study). American Journal of Cardiology, 121(5), pp. 570-578. (doi: 10.1016/j.amjcard.2017.11.030) (PMID:29310809)
Baumgartner, C. et al. (2017) Thyroid function within the normal range, subclinical hypothyroidism and the risk of atrial fibrillation. Circulation, 136(22), pp. 2100-2116. (doi: 10.1161/CIRCULATIONAHA.117.028753) (PMID:29061566)
Macfarlane, P. W., Mason, J. W., Kligfield, P., Sommargren, C. E., Drew, B., van Dam, P., Abächerli, R., Albert, D. E. and Hodges, M. (2017) Debatable issues in automated ECG reporting. Journal of Electrocardiology, 50(6), pp. 833-840. (doi: 10.1016/j.jelectrocard.2017.08.027) (PMID:28985886)
Weng, L.-C. et al. (2017) Genetic interactions with age, sex, body mass index, and hypertension in relation to atrial fibrillation: the AFGen consortium. Scientific Reports, 7, 11303. (doi: 10.1038/s41598-017-09396-7) (PMID:28900195) (PMCID:PMC5595875)
Iacoviello, L. et al. (2017) Frontal plane T-wave axis orientation predicts coronary events: Findings from the Moli-sani study. Atherosclerosis, 264, pp. 51-57. (doi: 10.1016/j.atherosclerosis.2017.07.021) (PMID:28772106)
Ray, D., Hazra, S., Goswami, D. P., Macfarlane, P. W. and Sengupta, A. (2017) An evaluation of planarity of the spatial QRS loop by three dimensional vectorcardiography: its emergence and loss. Journal of Electrocardiology, 50(5), pp. 652-660. (doi: 10.1016/j.jelectrocard.2017.03.016) (PMID:28366419)
Schutte, R., Whincup, P. H., Papacosta, O., Lennon, L. T., Macfarlane, P. W. and Wannamethee, G. (2017) Liver enzymes are not directly involved in atrial fibrillation: a prospective cohort study. European Journal of Clinical Investigation, 47(8), pp. 583-590. (doi: 10.1111/eci.12779) (PMID:28664600)
Pinto-Filho, M. M. et al. (2017) Major electrocardiographic abnormalities according to the Minnesota coding system among Brazilian adults (from the ELSA-Brasil cohort study). American Journal of Cardiology, 119(12), pp. 2081-2087. (doi: 10.1016/j.amjcard.2017.03.043) (PMID:28450038)
van den Berg, M. E. et al. (2017) Discovery of novel heart rate-associated loci using the Exome Chip. Human Molecular Genetics, 26(12), pp. 2346-2363. (doi: 10.1093/hmg/ddx113) (PMID:28379579) (PMCID:PMC5458336)
Palhares, D. M.F., Marcolino, M. S., Santos, T. M.M., da Silva, J. L.P., Gomes, P. R., Ribeiro, L. B., Macfarlane, P. W. and Ribeiro, A. L.P. (2017) Normal limits of the electrocardiogram derived from a large database of Brazilian primary care patients. BMC Cardiovascular Disorders, 17(1), 152. (doi: 10.1186/s12872-017-0572-8) (PMID:28610624) (PMCID:PMC5470250)
Christophersen, I. E. et al. (2017) Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation. Nature Genetics, 49(6), pp. 946-952. (doi: 10.1038/ng.3843) (PMID:28416818)
Elffers, T. W., de Mutsert, R., Lamb, H. J., Maan, A. C., Macfarlane, P. W., Willems van Dijk, K., Rosendaal, F. R., Jukema, J. W. and Trompet, S. (2017) Association of metabolic syndrome and electrocardiographic markers of subclinical cardiovascular disease. Diabetology and Metabolic Syndrome, 9, 40. (doi: 10.1186/s13098-017-0238-9) (PMID:28539979) (PMCID:PMC5441065)
Lubitz, S. A. et al. (2017) Genetic risk prediction of atrial fibrillation. Circulation, 135(14), pp. 1311-1320. (doi: 10.1161/CIRCULATIONAHA.116.024143) (PMID:27793994)
Stam-Slob, M. C. et al. (2017) Personalized absolute benefit of statin treatment for primary or secondary prevention of vascular disease in individual elderly patients. Clinical Research in Cardiology, 106(1), pp. 58-68. (doi: 10.1007/s00392-016-1023-8) (PMID:27554244) (PMCID:PMC5226996)
Bosson, N. et al. (2017) Causes of prehospital misinterpretations of ST elevation myocardial infarction. Prehospital Emergency Care, 21(3), pp. 283-290. (doi: 10.1080/10903127.2016.1247200) (PMID:27858506)
Mahinrad, S., Vriend, A. E., Jukema, J. W., van Heemst, D., Sattar, N. , Blauw, G. J., Macfarlane, P. W., Clark, E. N., de Craen, A. J.M. and Sabayan, B. (2017) Left ventricular hypertrophy and cognitive decline in old age. Journal of Alzheimer's Disease, 58(1), pp. 275-283. (doi: 10.3233/JAD-161150) (PMID:28387665)
Lin, H. et al. (2016) Gene-gene interaction analyses for atrial fibrillation. Scientific Reports, 6, 35371. (doi: 10.1038/srep35371) (PMID:27824142) (PMCID:PMC5099695)
van der Harst, P. et al. (2016) 52 genetic loci influencing myocardial mass. Journal of the American College of Cardiology, 68(13), pp. 1435-1448. (doi: 10.1016/j.jacc.2016.07.729) (PMID:27659466) (PMCID:PMC5478167)
Batchvarov, V. N., Bastiaenen, R., Postema, P. G., Clark, E., Macfarlane, P., Wilde, A. A.M. and Behr, E. R. (2016) Novel electrocardiographic criteria for the diagnosis of arrhythmogenic right ventricular cardiomyopathy. Europace, 18(9), pp. 1420-1426. (doi: 10.1093/europace/euv379) (PMID:26622053)
Salvi, V., Clark, E., Karnad, D. R., Macfarlane, P. W., Panicker, G. K., Hingorani, P. and Kothari, S. (2016) Comparison of the spatial QRS-T angle derived from digital ECGs recorded using conventional electrode placement with that derived from Mason-Likar electrode position. Journal of Electrocardiology, 49(5), pp. 714-719. (doi: 10.1016/j.jelectrocard.2016.06.006) (PMID:27395365)
Mahinrad, S., Jukema, J. W., van Heemst, D. v., Macfarlane, P. W., Clark, E. N., de Craen, A. J.M. and Sabayan, B. (2016) 10-Second heart rate variability and cognitive function in old age. Neurology, 86(12), pp. 1120-1127. (doi: 10.1212/wnl.0000000000002499) (PMID:26888988)
Drew, B. J., Sommargren, C. E., Tolan, G. D., Macfarlane, P. W., Wagner, G. S., Strauss, D. G., Burke, M. C., Kligfield, P. D., Rowlandson, I. and Lux, R. L. (2015) In memoriam: a tribute to the work and lives of Ron Selvester and Rory Childers. Journal of Electrocardiology, 48(6), pp. 1088-1098. (doi: 10.1016/j.jelectrocard.2015.08.037) (PMID:26422547)
Ogliari, G. et al. (2015) Resting heart rate, heart rate variability and functional decline in old age. Canadian Medical Association Journal, 187(15), E442-E449. (doi: 10.1503/cmaj.150462) (PMID:26323697) (PMCID:PMC4610849)
Macfarlane, P.W., Antzelevitch, C., Haissaguerre, M., Huikuri, H.V., Potse, M., Rosso, R., Sacher, F., Tikkanen, J.T., Wellens, H. and Yan, G.-X. (2015) The early repolarization pattern. Journal of the American College of Cardiology, 66(4), pp. 470-477. (doi: 10.1016/j.jacc.2015.05.033)
Macfarlane, P. W., Lloyd, S. M. , Singh, D., Hamde, S., Clark, E., Devine, B., Francq, B. G. and Kumar, V. (2015) Normal limits of the electrocardiogram in Indians. Journal of Electrocardiology, 48(4), pp. 652-668. (doi: 10.1016/j.jelectrocard.2015.04.013) (PMID:25990450)
Macfarlane, P. W. (2015) Normal limits of ECG measurements related to atrial activity using a modified limb lead system. Anadolu Kardiyoloji Dergisi/The Anatolian Journal of Cardiology, 15(1), p. 7. (doi: 10.5152/akd.2014.14170) (PMID:25550246)
Macfarlane, P.W., Katibi, I.A., Hamde, S.T., Singh, D., Clark, E., Devine, B., Francq, B., Lloyd, S. and Kumar, V. (2014) Racial differences in the ECG — selected aspects. Journal of Electrocardiology, 47(6), pp. 809-814. (doi: 10.1016/j.jelectrocard.2014.08.003)
Arking, D. E. et al. (2014) Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization. Nature Genetics, 46(8), pp. 826-836. (doi: 10.1038/ng.3014) (PMID:24952745) (PMCID:PMC4124521)
Higgins, P., Dawson, J. , Macfarlane, P. W., McArthur, K., Langhorne, P. and Lees, K. R. (2014) Predictive value of newly detected atrial fibrillation paroxysms in patients with acute ischemic stroke, for atrial fibrillation after 90 days. Stroke, 45(7), pp. 2134-2136. (doi: 10.1161/STROKEAHA.114.005405)
Lubitz, S.A. et al. (2014) Novel genetic markers associate with atrial fibrillation risk in Europeans and Japanese. Journal of the American College of Cardiology, 63(12), pp. 1200-1210. (doi: 10.1016/j.jacc.2013.12.015)
Clark, E. N., Katibi, I. and Macfarlane, P. W. (2014) Automatic detection of end QRS notching or slurring. Journal of Electrocardiology, 47(2), pp. 151-154. (doi: 10.1016/j.jelectrocard.2013.10.007)
Kligfield, P. et al. (2014) Comparison of automated measurements of electrocardiographic intervals and durations by computer-based algorithms of digital electrocardiographs. American Heart Journal, 167(2), 150-159.e1. (doi: 10.1016/j.ahj.2013.10.004) (PMID:24439975) (PMCID:24439975)
Lundby, A. et al. (2014) Annotation of loci from genome-wide association studies using tissue-specific quantitative interaction proteomics. Nature Methods, 11(8), pp. 868-874. (doi: 10.1038/NMETH.2997)
Sinner, M. F. et al. (2014) Integrating genetic, transcriptional, and functional analyses to identify 5 novel genes for atrial fibrillation. Circulation, 130(15), pp. 1225-1235. (doi: 10.1161/CIRCULATIONAHA.114.009892)
Macfarlane, P.W., Clark, E.N. and Heng, J.S. (2013) J wave patterns—morphology, prevalence and nomenclature. Journal of Electrocardiology, 46(6), pp. 505-509. (doi: 10.1016/j.jelectrocard.2013.08.013)
Macfarlane, P.W. (2013) The continuing renaissance of the resting 10s ECG. Journal of Electrocardiology, 46(5), pp. 383-384. (doi: 10.1016/j.jelectrocard.2013.06.029)
Macfarlane, P.W. and Clark, E.N. (2013) ECG measurements in end QRS notching and slurring. Journal of Electrocardiology, 46(5), pp. 385-389. (doi: 10.1016/j.jelectrocard.2013.06.011)
Katibi, I., Clark, E.N., Devine, B., Lloyd, S.M. and Macfarlane, P.W. (2013) Normal limits of the electrocardiogram in Nigerians. Journal of Electrocardiology, 46(4), pp. 289-295. (doi: 10.1016/j.jelectrocard.2013.04.002)
Nanchen, D. et al. (2013) Resting heart rate and incident heart failure and cardiovascular mortality in older adults: role of inflammation and endothelial dysfunction: the PROSPER study. European Journal of Heart Failure, 15(5), pp. 581-588. (doi: 10.1093/eurjhf/hfs195)
Higgins, P., Macfarlane, P. W., Dawson, J. , McInnes, G. T., Langhorne, P. and Lees, K. R. (2013) Noninvasive cardiac event monitoring to detect atrial fibrillation after ischemic stroke: a randomized, controlled trial. Stroke, 44(9), pp. 2525-2531. (doi: 10.1161/STROKEAHA.113.001927)
Welsh, P. , Doolin, O., Willeit, P., Packard, C. , Macfarlane, P., Cobbe, S., Gudnason, V., Di Angelantonio, E., Ford, I. and Sattar, N. (2013) N-terminal pro-B-type natriuretic peptide and the prediction of primary cardiovascular events: results from 15-year follow-up of WOSCOPS. European Heart Journal, 34(6), pp. 443-450. (doi: 10.1093/eurheartj/ehs239)
Heng, S.J., Clark, E.N. and Macfarlane, P.W. (2012) End QRS notching or slurring in the electrocardiogram: influence on the definition of "early repolarization". Journal of the American College of Cardiology, 60(10), pp. 947-948. (doi: 10.1016/j.jacc.2012.03.061)
Mihaylova, B. et al. (2012) The effects of lowering LDL cholesterol with statin therapy in people at low risk of vascular disease: meta-analysis of individual data from 27 randomised trials. Lancet, 380(9841), pp. 581-590. (doi: 10.1016/S0140-6736(12)60367-5)
Nanchen, D. et al. (2012) Subclinical thyroid dysfunction and the risk of heart failure in older persons at high cardiovascular risk. Journal of Clinical Endocrinology and Metabolism, 97(3), pp. 852-861. (doi: 10.1210/jc.2011-1978)
Emberson, J.R. et al. (2012) Lack of effect of lowering LDL cholesterol on cancer: meta-analysis of individual data from 175,000 people in 27 randomised trials of statin therapy. PLoS ONE, 7(1), e29849. (doi: 10.1371/journal.pone.0029849) (PMID:22276132) (PMCID:PMC3261846)
Gaunt, T.R. et al. (2012) Integration of genetics into a systems model of electrocardiographic traits using humanCVD BeadChip. Circulation: Cardiovascular Genetics, 5(6), pp. 630-638. (doi: 10.1161/CIRCGENETICS.112.962852)
Lindekliev, H., Wilsgaard, T., Macfarlane, P.W. and Lochen, M. (2012) QT interval and the risk of myocardial infarction and all-cause death: A cohort study. Journal of Cardiovascular Electrophysiology, 23(8), pp. 846-852. (doi: 10.1111/j.1540-8167.2012.02308.x)
Luo, S., Johnston, P. and Macfarlane, P.W. (2012) Implanted cardiac pacemaker pulses as recorded from the body surface. Journal of Electrocardiology, 45(6), pp. 663-669. (doi: 10.1016/j.jelectrocard.2012.08.008)
Pierce, M.B. et al. (2012) Clinical disorders in a post war British cohort reaching retirement: evidence from the First National Birth Cohort Study. PLoS ONE, 7(9), e44857. (doi: 10.1371/journal.pone.0044857) (PMID:23028647) (PMCID:PMC3447001)
van Es, A.C.G.M. et al. (2011) Cerebral microbleeds and cognitive functioning in the PROSPER study. Neurology, 77(15), pp. 1446-1452. (doi: 10.1212/WNL.0b013e318232ab1d)
Widya, R. L. et al. (2011) Increased amygdalar and hippocampal volumes in elderly obese individuals with or at risk of cardiovascular disease. American Journal of Clinical Nutrition, 93(6), pp. 1190-1195. (doi: 10.3945/ajcn.110.006304)
Logue, J. , Murray, H.M., Welsh, P. , Shepherd, J., Packard, C. , Macfarlane, P., Cobbe, S., Ford, I. and Sattar, N. (2011) Obesity is associated with fatal coronary heart disease independently of traditional risk factors and deprivation. Heart, 97(7), pp. 564-568. (doi: 10.1136/hrt.2010.211201)
Rahimi, K. et al. (2011) Effect of statins on atrial fibrillation: collaborative meta-analysis of published and unpublished evidence from randomised controlled trials. British Medical Journal, 342, d1250. (doi: 10.1136/bmj.d1250)
Macfarlane, P.W., Murray, H., Sattar, N. , Stott, D.J. , Ford, I. , Buckley, B., Jukema, J.W., Westendorp, R.G.J. and Shepherd, J. (2011) The incidence and risk factors for new onset atrial fibrillation in the PROSPER study. Europace, 13(5), pp. 634-639. (doi: 10.1093/europace/eur016)
Mutsaerts, H.J.M.M. et al. (2011) Diastolic carotid artery wall shear stress is associated with cerebral infarcts and periventricular white matter lesions. Stroke, 42(12), pp. 3497-3501. (doi: 10.1161/STROKEAHA.111.614453)
Nunn, L.M., Bhar-Amato, J., Lowe, M.D., Macfarlane, P.W., Rogers, P., McKenna, W.J., Elliott, P.M. and Lambiase, P. D. (2011) Prevalence of J-Point Elevation in Sudden Arrhythmic Death Syndrome Families. Journal of the American College of Cardiology, 58(3), pp. 286-290. (doi: 10.1016/j.jacc.2011.03.028)
Pons, D. et al. (2011) Genetic variation in PCAF, a key mediator in epigenetics, is associated with reduced vascular morbidity and mortality: evidence for a new concept from three independent prospective studies. Heart, 97(2), pp. 143-150. (doi: 10.1136/hrt.2010.199927)
Reinhard, W., Kaess, B. M., Debiec, R., Nelson, C. P., Stark, K., Tobin, M. D., Macfarlane, P.W., Tomaszewski, M., Samani, N. J. and Hengstenberg, C. (2011) Heritability of Early Repolarization: A Population-Based Study. Circulation: Cardiovascular Genetics, 4(2), pp. 134-138. (doi: 10.1161/CIRCGENETICS.110.958298)
Shah, S. et al. (2011) Four genetic loci influencing electrocardiographic indices of left ventricular hypertrophy. Circulation: Cardiovascular Genetics, 4(6), pp. 626-635. (doi: 10.1161/CIRCGENETICS.111.960203)
Sosnowski, M., Macfarlane, P.W. and Tendera, M. (2011) Determinants of a reduced heart rate variability in chronic atrial fibrillation. Annals of Noninvasive Electrocardiology, 16(4), pp. 321-326. (doi: 10.1111/j.1542-474X.2011.00458.x)
Surawicz, B. and Macfarlane, P.W. (2011) Inappropriate and Confusing Electrocardiographic Terms. Journal of the American College of Cardiology, 57(15), pp. 1584-1586. (doi: 10.1016/j.jacc.2010.11.040)
Caslake, M.J. et al. (2010) Lipoprotein-associated phospholipase A2 inflammatory biomarkers, and risk of cardiovascular disease in the Prospective Study of Pravastatin in the Elderly at Risk (PROSPER). Atherosclerosis, 210(1), pp. 28-34. (doi: 10.1016/j.atherosclerosis.2009.10.041)
Sattar, N. et al. (2010) Statins and risk of incident diabetes: a collaborative meta-analysis of randomised statin trials. Lancet, 375(9716), pp. 735-742. (doi: 10.1016/S0140-6736(09)61965-6)
Trompet, S. et al. (2010) Pravastatin and cognitive function in the elderly. Results of the PROSPER study. Journal of Neurology, 257(1), pp. 85-90. (doi: 10.1007/s00415-009-5271-7)
Welsh, P. et al. (2010) Unraveling the directional link between adiposity and inflammation: a bidirectional mendelian randomization approach. Journal of Clinical Endocrinology and Metabolism, 95(1), pp. 93-99. (doi: 10.1210/jc.2009-1064)
Batchvarov, V. N., Govindan, M., Macfarlane, P., Camm, A. J. and Behr, E. R. (2010) Diagnostic utility of bipolar precordial leads during ajmaline testing for suspected Brugada syndrome. Heart Rhythm, 7(2), pp. 208-215. (doi: 10.1016/j.hrthm.2009.10.005)
Clark, E.N., Sejersten, M., Clemmensen, P. and Macfarlane, P.W. (2010) Automated electrocardiogram interpretation programs versus cardiologists' triage decision making based on teletransmitted data in patients with suspected acute coronary syndrome. American Journal of Cardiology, 106(12), pp. 1696-1702. (doi: 10.1016/j.amjcard.2010.07.047)
Katibi, I., Clark, E., Devine, B., Lloyd, S. and Macfarlane, P.W. (2010) Comparison of QRS duration in African blacks and European caucasians. Computing in Cardiology, 37, pp. 701-704.
Preiss, D. , Welsh, P. , Murray, H., Shepherd, J., Packard, C. , Macfarlane, P., Cobbe, S., Ford, I. and Sattar, N. (2010) Fasting plasma glucose in non-diabetic participants and the risk for incident cardiovascular events, diabetes, and mortality: results from WOSCOPS 15-year follow-up(dagger). European Heart Journal, 31(10), pp. 1230-1236. (doi: 10.1093/eurheartj/ehq095)
Welsh, P. et al. (2009) Leptin Predicts Diabetes but Not Cardiovascular Disease Results from a large prospective study in an elderly population. Diabetes Care, 32(2), pp. 308-310. (doi: 10.2337/dc08-1458)
Macfarlane, P. (2009) The International Society of Electrocardiology. Journal of Electrocardiology, 42(3), pp. 221-222.
Sattar, N.A. et al. (2009) Are markers of inflammation more strongly associated with risk for fatal than for nonfatal vascular events? PLoS Medicine, 6(6), e1000099. (doi: 10.1371/journal.pmed.1000099)
Sattar, N. et al. (2009) Are elevated circulating intercellular adhesion molecule 1 levels more strongly predictive of diabetes than vascular risk? Outcome of a prospective study in the elderly. Diabetologia, 52(2), pp. 235-239.
Sattar, N. et al. (2008) Can metabolic syndrome usefully predict cardiovascular disease and diabetes? Outcome data from two prospective studies. Lancet, 371(9628), pp. 1927-1935. (doi: 10.1016/S0140-6736(08)60602-9)
Downs, J.R. et al. (2008) Efficacy of cholesterol-lowering therapy in 18 686 people with diabetes in 14 randomised trials of statins: a meta-analysis. Lancet, 371(9607), pp. 117-125. (doi: 10.1016/S0140-6736(08)60104-X)
Belch, J. et al. (2008) The prevention of progression of arterial disease and diabetes (POPADAD) trial: factorial randomised placebo controlled trial of aspirin and antioxidants in patients with diabetes and asymptomatic peripheral arterial disease. British Medical Journal, 337, a1840. (doi: 10.1136/bmj.a1840)
De Ruijter, W., Assendelft, W., Macfarlane, P., Westendorp, R. and Gussekloo, J. (2008) The additional value of routine electrocardiograms in cardiovascular risk management of older people - The Leiden 85-plus Study: An observational, prospective cohort study. Scandinavian Journal of Primary Health Care, 26(3), pp. 147-153. (doi: 10.1080/02813430802095812)
Sohaib, S., Papacosta, O., Morris, R., Macfarlane, P. and Whincup, P. (2008) Length of the QT interval: determinants and prognostic implications in a population-based prospective study of older men. Journal of Electrocardiology, 41(6), pp. 704-710.
Trompet, S. et al. (2008) Lymphotoxin-alpha C804A polymorphism is a risk factor for stroke. The PROSPER study. Experimental Gerontology, 43(8), pp. 801-805. (doi: 10.1016/j.exger.2008.04.006)
Trompet, S. et al. (2008) Genetic variation in the interleukin-1 beta-converting enzyme associates with cognitive function. The PROSPER study. Brain, 131(4), pp. 1069-1077. (doi: 10.1093/brain/awn023)
Packard, C.J. et al. (2007) Association between apolipoprotein E4 and cognitive decline in elderly adults. Journal of the American Geriatrics Society, 55(11), pp. 1777-1785. (doi: 10.1111/j.1532-5415.2007.01415.x)
Sattar, N. , McConnachie, A. , Ford, I. , Gaw, A., Cleland, S.J., Forouhi, N.G., Macfarlane, P., Shepherd, J., Cobbe, S. and Packard, C. (2007) Serial metabolic measurements and conversion to type 2 diabetes in the West of Scotland Coronary Prevention Study - Specific elevations in alanine aminotransferase and triglycerides suggest hepatic fat accumulation as a potential contributing factor. Diabetes, 56(4), pp. 984-991. (doi: 10.2337/db06-1256)
Barber, M., Barlow, N., Macfarlane, P., Morton, J., Roditi, G. and Stott, D. (2007) Elevated troponin levels are associated with sympathoadrenal activation in acute ischaemic stroke. Cerebrovascular Diseases, 23, pp. 260-266. (doi: 10.1159/000098325)
Barber, M., Morton, J., Macfarlane, P., Barlow, N., Roditi, G. and Stott, D. (2007) Elevated troponin levels are associated with sympathoadrenal activation in acute ischaemic stroke. Cerebrovascular Diseases, 23, pp. 260-266.
Clark, E., Macfarlane, P.W., McGavigan, A.D., Quinn, R. and Rankin, A.C. (2007) Localization of accessory pathways in the Wolff-Parkinson-White pattern - Physician versus computer interpretation of the same algorithm. Pacing and Clinical Electrophysiology, 30, pp. 998-1002.
de Ruijter, W., Westendorp, R., Macfarlane, P., Jukema, J., Assendelft, W. and Gussekloo, J. (2007) The routine electrocardiogram for cardiovascular risk stratification in old age: The Leiden 85 plus Study. Journal of the American Geriatrics Society, 55, pp. 872-877.
de Ruijter, W., Westendorp, R., Macfarlane, P., Jukema, J., Assendelft, W. and Gussekloo, J. (2007) The routine electrocardiogram for cardiovascular risk stratification in old age: The leiden 85-plus study. Journal of the American Geriatrics Society, 55, pp. 872-877. (doi: 10.1111/j.1532-5415.2007.01180.x)
Fayn, J., Rubel, P. and Macfarlane, P. (2007) Can the lessons learned from the assessment of automated electrocardiogram analysis in the common standards for quantitative Electrocardiography study benefit measurement of delayed contrast-enhanced magnetic reasonance images? Journal of Electrocardiology, 40, pp. 872-877.
Ford, I., Murray, H., Shepherd, J., Packard, C. , Macfarlane, P. and Cobbe, S. (2007) Long-term follow-up of the West of Scotland Coronary Prevention Study. New England Journal of Medicine, 357(15), pp. 1477-1486. (doi: 10.1056/NEJMoa065994)
Kligfield, P. et al. (2007) Guidelines for the standardization and interpretation of the electrocardiogram, Part 1: The electrocardiogram and its technology. Circulation, 115, pp. 1306-1324.
Macfarlane, P. (2007) The Pierre Rijlant Lecture 2007: The Future of Elecctrocardiology. Anatolian Journal of Cardiology, 7(Suppl), pp. 1-4.
Macfarlane, P. (2007) Update on ACC/ESC criteria for acute ST elevation myocardial infarction in : Gulizia M,M.(ed). Current News in Cardiology, pp. 341-345.
Macfarlane, P., Hampton, D., Clark, E., Devine, B. and Jayne, C. (2007) Computer analysis of implanted Cardiac Pacemaker Rhythm. Computers in Cardiology, 34, pp. 293-296.
Macfarlane, P., Hampton, D., Clark, E., Devine, B. and Jayne, C. (2007) Evaluation of Age and Sex Dependent Criteria for ST Elevation Myocardial Infarction. Computers in Cardiology, 34, pp. 293-296.
Macfarlane, P. and Norrie, J. (2007) The value of the electrocardiogram in risk assessment in primary prevention: Experience from the West of Scotland Coronary Prevention Study. Journal of Electrocardiology, 40, pp. 101-109. (doi: 10.1016/j.jelectrocard.2006.05.003)
Macfarlane, P. and Norrie, J. (2007) The value of the electrocardiogram in risk assessment in primary prevention: Experience from the West of Scotland Coronary Prevention Study. Journal of Electrocardiology, 40, pp. 101-109.
McGavigan, A., Clark, E., Quinn, R., Rankin, A. and Macfarlane, P. (2007) Localization of accessory pathways in the Wolff-Parkinson-White pattern - Physician versus computer interpretation of the same algorithm. Pacing and Clinical Electrophysiology, 30, pp. 998-1002.
Sattar, N. et al. (2007) C-reactive protein and prediction of coronary heart disease and global vascular events in the prospective study of pravastatin in the elderly at risk (PROSPER). Circulation, 115(8), pp. 981-989. (doi: 10.1161/CIRCULATIONAHA.106.643114)
Trompet, S. et al. (2007) Genetic variation in the interleukin-10 gene promoter and risk of coronary and cerebrovascular events: the PROSPER Study. Annals of the New York Academy of Sciences, 1100, pp. 189-198.
Clark, E., Cleland, J., Gemmell, I., Khand, A., Macfarlane, P. and Rankin, A. (2006) The assessment of autonomic function in chronic atrial fibrillation: description of a non-invasive technique based on circadian rhythm of atrioventricular nodal functional refractory periods. Europace, 8, pp. 927-934. (doi: 10.1093/europace/eul111)
Clark, E., Devine, B. and Macfarlane, P. (2006) Age and Sex Dependent Criteria for Lower Limits of QRS Voltages. Computers in Cardiology, 33, pp. 81-84.
Gordon, M. et al. (2006) A means to an endpoint. Good Clinical Practice Journal, 13(10), pp. 25-29.
Gordon, M. et al. (2006) A means to an endpoint. Good Clinical Practice Journal, 13(10), pp. 25-29.
Khand, A., Rankin, A., Cleland, J., Gemmell, I., Clark, E. and Macfarlane, P. (2006) The assessment of autonomic function in chronic atrial fibrillation: description of a non-invasive technique based on circadian rhythm of atrioventricular nodal functional refractory periods. Europace, 8, pp. 927-934.
Macfarlane, P. (2006) Is electrocardiography still useful in the diagnosis of cardiac chamber hypertrophy and dilatation? Cardiology Clinics, 24, 401-+. (doi: 10.1016/j.ccl.2006.04.013)
Sosnowski, M., Macfarlane, P., Parma, R., Skrzypek-Wanha, J. and Tendera, M. (2006) Prognostic Value of Heart Rate Variability Analysis in Patients with Depressed Left Ventricular Function Irrespective of Cardiac Rhythm. Computers in Cardiology, 33, pp. 81-84.
van Bemmel, T., Vinkers, D., Macfarlane, P., Gussekloo, J. and Westendorp, R. (2006) Markers of autonomic tone on a standard ECG are predictive of mortality in old age. International Journal of Cardiology, 107, pp. 36-41. (doi: 10.1016/j.ijcard.2005.02.031)
van Bemmel, T., Vinkers, D., Macfarlane, P., Gussekloo, J. and Westendorp, R. (2006) Markers of autonomic tone on a standard ECG are predictive of mortality in old age. International Journal of Cardiology, 107, pp. 36-41.
Verluis, C. et al. (2006) Progression of cerebral white matter lesions is not associated with development of depressive symptoms in elderly subjects at risk of cardiovascular disease. The PROSPER Study. International Journal of Geriatric Psychiatry, 21(4), pp. 375-381.
Wagner, G. et al. (2006) Consideration of pitfalls in and omissions from the current ECG Standards for diagnosis of Myocardial Ischemia/Infarction in patients who have Acute Coronary Syndromes. Cardiology Clinics, 24, pp. 331-342.
Stott, D. J. et al. (2005) Randomized controlled trial of homocysteine-lowering vitamin treatment in elderly patients with vascular disease. American Journal of Clinical Nutrition, 82(6), pp. 1320-1326. (doi: 10.1093/ajcn/82.6.1320) (PMID:16332666)
Bootsma-van der Wiel, A., de Craen, A. J.M., van Exel, E., Macfarlane, P. W., Gussekloo, J. and Westendorp, R. G.J. (2005) Association between chronic diseases and disability in elderly subjects with low and high income: the Leiden 85-plus study. European Journal of Public Health, 15(5), pp. 494-497. (doi: 10.1093/eurpub/cki015) (PMID:16014663)
Hamilton, R.M., McLeod, K., Houston, A.B. and Macfarlane, P.W. (2005) Inter and Intraobserver Variability in LVH and RVH Reporting in Paediatric ECGs. Annals of Noninvasive Electrocardiology, 10(3), pp. 330-333.
Hamilton, R., Houston, A., McLeod, K. and Macfarlane, P. (2005) Evaluation of paediatric electrocardiogram diagnosis of ventricular hypertrophy by computer program compared with cardiologists. Paediatric Cardiology, 26, pp. 373-378.
Hamilton, R., Houston, A., McLeod, K. and Macfarlane, P. (2005) Evaluation of pediatric electrocardiogram diagnosis of ventricular hypertrophy by computer program compared with cardiologists. Pediatric Cardiology, 26, pp. 373-378. (doi: 10.1007/s00246-004-0748-8)
Hamilton, R., McLeod, K., Houston, A. and Macfarlane, P. (2005) Inter- and intraobserver variability in LVH and RVH reporting in pediatric ECGs. Annals of Noninvasive Electrocardiology, 10, pp. 330-333.
Macfarlane, P., Devine, B. and Clark, E. (2005) The University of Glasgow (Uni-G) ECG Analysis Program. Computers in Cardiology, 32, pp. 451-454.
Macfarlane, P., Rubel, P. and van Bemmel, J. (2005) Christoph Zywietz 1937-2005 - In memoriam. Journal of Electrocardiology, 38, pp. 404-405.
Madias, J.E. and MacFarlane, P.W. (2005) Artificial attenuation of ECG voltage produces shortening of the corresponding QRS duration: Clinical implications for patients with edema. Pacing and Clinical Electrophysiology, 28, pp. 1060-1065.
Packard, C.J. et al. (2005) Plasma lipoproteins and apolipoproteins as predictors of cardiovascular risk and treatment benefit in the PROspective Study of Pravastatin in the Elderly at Risk (PROSPER). Circulation, 112, pp. 3058-3065. (doi: 10.1161/CIRCULATIONAHA.105.526848)
Sosnowski, M., Clark, E., Latif, S., Macfarlane, P.W. and Tendera, M. (2005) Heart rate variability fraction - a new reportable measure of 24-hour R-R interval variation. Annals of Noninvasive Electrocardiology, 10, pp. 7-15. (doi: 10.1111/j.1542-474X.2005.00579.x)
Drew, B., Califf, R., Funk, M., Kaufman, E., Krucoff, M., Laks, M., Macfarlane, P., Sommargren, C., Swiryn, S. and Van Hare, G. (2004) Practice standards for electrocardiographic monitoring in hospital settings. Circulation, 110, pp. 2721-2746.
Hamilton, R., Mckechnie, P. and Macfarlane, P. (2004) Can cardiac vagal tone be estimated from the 10-second ECG? International Journal of Cardiology, 95, pp. 109-115. (doi: 10.1016/j.ijcard.2003.07.002)
Hamilton, R., McKechnie, P. and Macfarlane, P. (2004) Can cardiac vagal tone by estimated from the 10-second ECG? International Journal of Cardiology, 95, pp. 109-115.
Hodgart, E. and Macfarlane, P. (2004) 10 Second Heart Rate Variability. Computers in Cardiology, 31, pp. 217-220.
Kumar, R., Fisher, M. and Macfarlane, P. (2004) Diabetes and the QT interval: time for debate. British Journal of Diabetes and Vascular Disease, 4, pp. 146-150.
Kumar, R., Fisher, M., Whitaker, R. and Macfarlane, P. (2004) Effect of controlling hyperglycemia with diet on QT abnormalities in newly diagnosed patients with type 2 diabetes. Diabetes Care, 27, pp. 2767-2768.
Ledmyr, H., McMahon, A., Ehrenborg, E., Nielsen, L., Neville, M., Litchell, H., Macfarlane, P., Packard, C. and Karpe, F. (2004) The microsomal triglyceride transfer protein gene-493T variant lowers cholesterol but increases the risk of coronary heart disease. Circulation, 109, pp. 2279-2284.
Ledmyr, H., McMahon, A. , Ehrenborg, E., Nielsen, L., Neville, M., Lithell, H., MacFarlane, P., Packard, C. and Karpe, F. (2004) The microsomal triglyceride transfer protein gene-493T variant lowers cholesterol but increases the risk of coronary heart disease. Circulation, 109, pp. 2279-2284. (doi: 10.1161/01.CIR.0000130070.96758.7b)
Luo, S., Michler, K., Johnston, P. and Macfarlane, P. (2004) A comparison of commonly used QT correction formulae: The effect of heart rate on the QTc of normal ECGs. Journal of Electrocardiology, 37, pp. 81-90. (doi: 10.1016/j.jelectrocard.2003.08.030)
Macfarlane, P., Browne, D., Devine, B., Clark, E., Miller, E., Seyal, J. and Hampton, D. (2004) Effect of age and gender on diagnostic accuracy of ECG diagnosis of Acute Myocardial Infarction. Computers in Cardiology, 31, pp. 165-168.
Macfarlane, P., Browne, D., Devine, B., Clark, E., Miller, E., Seyal, J. and Hampton, D. (2004) Modification of ACC/ESC criteria for acute myocardial infarction. Journal of Electrocardiology, 37, pp. 98-103. (doi: 10.1016/j.jelectrocard.2004.08.032)
Macfarlane, P., Browne, D., Devine, B., Clark, E., Miller, E., Seyal, J. and Hampton, D. (2004) Modification of ACC/ESC criteria for acute myocardial infarction. Journal of Electrocardiology, 37((Suppl), pp. 98-103.
Macfarlane, P. and Norrie, J. (2004) Looking for prognostic information in the ST-T segment - Is it really worth it? Journal of Electrocardiology, 37, pp. 209-213.
Padmanabhan, S. , Connell, J.M.C., Dominiczak, A.F. , Inglis, G., Macfarlane, P.W. and Watt, G. (2004) Heritability and genetic determinants of electrocardiographic measures of left ventricular mass - a two generation family study. Journal of Hypertension: Supplement, 22(S1), S180-S181.
Petelenz, M., Conciarz, M., Macfarlane, P., Rudner, R., Kawecki, P., Musialik, J., Jalowiecki, P. and Gonciarz, Z. (2004) Sympathovagal balance fluctuates during colonoscopy. Endoscopy, 36, pp. 508-514.
Petelenz, M., Gonciarz, M., Macfarlane, P., Rudner, R., Kawecki, P., Musialik, J., Jalowiecki, P. and Gonciarz, Z. (2004) Sympathovagal balance fluctuates during colonoscopy. Endoscopy, 36, pp. 508-514. (doi: 10.1055/s-2004-814402)
Sattar, N. et al. (2004) Metabolic syndrome and diabetes mellitus - Response. Circulation, 109, E23-E23.
Sattar, N., Scherbakova, O., Ford, I., O'Reilly, D., Stanley, A., Forrest, E., MacFarlane, P., Packard, C. , Cobbe, S. and Shepherd, J. (2004) Elevated alanine aminotransferase predicts new-onset type 2 diabetes independently of classical risk factors, metabolic syndrome, and C-reactive protein in the West of Scotland Coronary Prevention Study. Diabetes, 53(11), pp. 2855-2860. (doi: 10.2337/diabetes.53.11.2855)
Sattar, N., Scherbakova, O., Ford, I., O'Reilly, D., Stanley, A., Forrest, E., Macfarlane, P., Packard, C. and Shepherd, J. (2004) Elevated alanine aminotransferase predicts new-onset type 2 diabetes independently of classical risk factors, metabolic syndrome and C-reactive protein in the West of Scotland Coronary Prevention Study. Diabetes, 53, pp. 2855-2860.
Corlan, A.D., Macfarlane, P.W. and De Ambroggi, L. (2003) Gender differences in stability of the instantaneous patterns of body surface potentials during ventricular repolarisation. Medical and Biological Engineering and Computing, 41(5), pp. 536-542. (doi: 10.1007/BF02345315)
Sattar, N. et al. (2003) Metabolic syndrome with and without C-reactive protein as a predictor of coronary heart disease and diabetes in the West of Scotland Coronary Prevention Study. Circulation, 108(4), pp. 414-419. (doi: 10.1161/01.CIR.0000080897.52664.94) (PMID:12860911)
Cleland, J.G.F. , Pennell, D.J., Ray, S.G., Coats, A.J., Macfarlane, P.W., Murray, G.D., Mule, J.D., Vered, Z. and Lahiri, A. (2003) Myocardial viability as a determinant of the ejection fraction response to Carvedilol in patients with heart failure (CHRISTMAS trial): randomised controlled trial. Lancet, 362(9377), pp. 14-21. (doi: 10.1016/S0140-6736(03)13801-9) (PMID:12853194)
de Craen, A.J.M., Gussekloo, J., Teng, Y.K., Macfarlane, P.W. and Westendorp, R.G.J. (2003) Prevalence of five common clinical abnormalities in very elderly people: population based cross sectional study. British Medical Journal, 327(7407), pp. 131-132. (doi: 10.1136/bmj.327.7407.131)
Hemingway, H., Shipley, M., Britton, A., Page, M., Macfarlane, P. and Marmot, M. (2003) Prognosis of angina with and without a diagnosis: 11 year follow up in the Whitehall II prospective cohort study. British Medical Journal, 327, pp. 895-898.
Huwez, F. and Macfarlane, P. (2003) Assessment of selected ECG voltage criteria for abnormality in eccentric and concentric left ventricular hypertrophy. Computers in Cardiology, 30, pp. 57-59.
Huwez, F. and Macfarlane, P. (2003) The influence of Q wave acute anteroseptal myocardial infarction on the voltage criteria for left ventricular hypertrophy. Computers in Cardiology, 30, pp. 815-818.
Macfarlane, P. (2003) The History of the International Society of Electrocardiology. International Journal of Bioelectromagnetism, 5(1), pp. 36-41.
Macfarlane, P., Colaco, R., Stevens, K., Reay, P., Beckett, C. and Aitchison, T. (2003) Precordial electrode placement in women. Netherlands Heart Journal, 11, pp. 118-122.
Oberstein, S., Jukema, J., van Duinen, S., Macfarlane, P., van Howelingen, H., Breuning, M., Ferrari, M. and Haan, J. (2003) Myocardial infarction in cerebral autosomal dominant Arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL). Medicine, 82, pp. 251-256.
Paracha, M., Mohammad, S., Macfarlane, P. and Jenkins, J. (2003) Implementation of Web Database for ECG. Computers in Cardiology, 30, pp. 271-274.
Paracha, M., Mohammad, S., Macfarlane, P. and Jenkins, J. (2003) Real-time custom processing and delivery of large ECG data sets. Computers in Cardiology, 30, pp. 411-412.
van Exel, E. et al. (2003) Interaction of atherosclerosis and inflammation in elderly subjects with poor cognitive function. Neurology, 61, pp. 1695-1701.
Ford, I. et al. (2002) A prospective study of pravastatin in the elderly at risk (PROSPER): Screening experience and baseline characteristics. Current Controlled Trials in Cardiovascular Medicine, 3, p. 8. (doi: 10.1186/1468-6708-3-8)
Houx, P.J. et al. (2002) Testing cognitive function in elderly populations: the PROSPER study. Journal of Neurology, Neurosurgery and Psychiatry, 73(4), pp. 385-389. (doi: 10.1136/jnnp.73.4.385)
Macfarlane, P. (2002) Gender dependent normal limits of ST-T amplitudes. International Journal of Bioelectromagnetism, 4, pp. 37-39.
McKechnie, P., Hamilton, R. and Macfarlane, P. (2002) Exercise levels predict cardiac vagal tone as measured by the Neuroscope. International Journal of Bioelectromagnetism, 4, pp. 309-310.
Robertson, A., Clark, E., van Oosterom, A. and Macfarlane, P. (2002) ECG monitoring using a limited lead set. International Journal of Bioelectromagnetism, 4, pp. 295-298.
Sattar, N., Macfarlane, P., Packard, C., Kelly, A., Shepherd, J., Gaw, A., Wallace, A. and McMahon, A. (2002) Plasma leptin levels and coronary heart disease - Response. Circulation, 106, E42-E42.
Seyal, J., Clark, E. and Macfarlane, P. (2002) Diagnosis of acute myocardial ischaemia using probabilistic methods. Journal of Cardiovascular Risk, 9(2), pp. 115-121.
Seyal, J., Clark, E. and Macfarlane, P. (2002) Diagnosis of acute myocardial ischaemia using probabilistic methods. Journal of Cardiovascular Risk, 9, pp. 115-121.
Shepherd, J. et al. (2002) Pravastatin in elderly individuals at risk of vascular disease (PROSPER): a randomised controlled trial. Lancet, 360(9346), pp. 1623-1630. (doi: 10.1016/S0140-6736(02)11600-X)
Shepherd, J. et al. (2002) Pravastatin in elderly individuals at risk of vascular disease (PROSPER) at randomised controlled trial. Lancet, 360(9346), pp. 1623-1630.
Sosnowski, M., MacFarlane, P., Czyz, Z., Skrzypek-Wanha, J., Boczkowska-Gaika, E. and Tendera, M. (2002) Age-adjustment of HRV measures and its prognostic value for risk assessment in patients late after myocardial infarction. International Journal of Cardiology, 86, pp. 249-258.
van Exel, E., de Craen, A., Gussekloo, J., Houx, P., Bootsma-van der Wiel, A. and Macfarlane, P. (2002) Association between high-density lipoprotein and cognitive impairment in the oldest old. Annals of Neurology, 51, pp. 716-721.
van Exel, E., Gussekloo, J., Houx, P., de Craen, A., Macfarlane, P., Bootsma-van der Wiel, A., Blauw, G. and Westendorp, R. (2002) Atherosclerosis and cognitive impairment are linked in the elderly. The Leiden 85-plus Study. Atherosclerosis, 165, pp. 353-359.
van Exel, E., Gussekloo, J., Houx, P., de Craen, A., Macfarlane, P., Bootsma-van der Wiel, A., Blauw, G. and Westendorp, R. (2002) Atherosclerosis and cognitive impairment are linked in the elderly. The Leiden 85-plus study. Atherosclerosis, 165, pp. 353-359.
Anderston, S. et al. (2001) Standards for the function of an academic 12-lead electrocardiographic core laboratory. Journal of Electrocardiology, 34, pp. 41-47.
Ford, I., McMahon, A., Pell, J., Packard, C., Macfarlane, P., Cobbe, S. and Shepherd, J. (2001) The prognostic value for stroke of a nurse-led screening assessment of 71,527 Scottish middle-aged men. Journal of the American College of Cardiology, 37, 226A.
Freeman, D. et al. (2001) Do statins reduce the risk for diabetes by improving exercise capacity? Response. Circulation, 104, E104-E105.
Freeman, D. et al. (2001) Pravastatin and the development of Diabetes Mellitus. Evidence for a Protective Treatment Effect in the West of Scotland Coronary Prevention Study. Circulation, 103, pp. 357-362.
Freeman, D. et al. (2001) Pravastatin and the development of diabetes mellitus - Evidence for a protective treatment effect in the West of Scotland Coronary Prevention Study. Circulation, 103(3), pp. 357-362.
Jacobsen, J., Wagner, G., Holmvang, L., Macfarlane, P., Naslund, U., Grande, P. and Clemmensen, P. (2001) Clinical significance of abnormal T waves in patients with non-ST-segment elevation acute coronary syndromes. American Journal of Cardiology, 88, pp. 1225-1229.
Jacobsen, M., Wagner, G., Holmvang, L., Macfarlane, P., Naslund, U., Grande, P., Clemmensen, P. and TRIM Investigators, (2001) Clinical significance of abnormal T waves in patients with non-ST-segment elevation acute coronary syndromes. American Journal of Cardiology, 88, pp. 1225-1229.
Macfarlane, P. (2001) Age, sex and the ST amplitude in Health and Disease. Journal of Electrocardiology, 34((Suppl), pp. 235-241.
Macfarlane, P. (2001) Age, sex, and the ST amplitude in health and disease. Journal of Electrocardiology, 34, pp. 235-241.
Mamode, N., Docherty, G., Lowe, G.D.O., Macfarlane, P.W., Martin, W., Pollock, J.G. and Cobbe, S.M. (2001) The role of myocardial perfusion scanning, heart rate variability and D-dimers in predicting the risk of perioperative cardiac complications after peripheral vascular surgery. European Journal of Vascular and Endovascular Surgery, 22(6), pp. 499-508. (doi: 10.1053/ejvs.2001.1529)
Murray, P., Hamilton, R. and Macfarlane, P. (2001) Reproducibility of a non-invasive real-time measure of cardiac parasympathetic activity. Physiological Measurement, 22, pp. 661-672.
Murray, P., Hamilton, R. and Macfarlane, P. (2001) Reproducibility of a non-invasive real-time measure of cardiac parasympathetic activity. Physiological Measurement, 22, pp. 661-672.
Morrison, S. and Macfarlane, P.W. (2000) Computer detection of atrial flutter. Annals of Noninvasive Electrocardiology, 5(4), pp. 358-364. (doi: 10.1111/j.1542-474X.2000.tb00074.x)
Calaco, R., Reay, P., Beckett, C., Aitchison, T. and Macfarlane, P. (2000) False positive ECG reports of anterior myocardial infarction in women. Journal of Electrocardiology, 33((Suppl), pp. 239-244.
Clark, L., Watson, J., Cobbe, S., Reeve, W., Swann, I. and Macfarlane, P. (2000) CPR '98: A practical multimedia computer-based guide to cardiopulmonary resuscitation for medical students. Resuscitation, 44, pp. 109-117.
Lowe, G., Rumley, A., Norrie, J., Ford, I. , Shepherd, J., Cobbe, S., Macfarlane, P. and Packard, C. (2000) Blood rheology, cardiovascular risk factors, and cardiovascular disease: The West of Scotland Coronary Prevention Study. Thrombosis and Haemostasis, 84(4), pp. 553-558.
Macfarlane, P. (2000) Minnesota coding and prevalence of ECG abnormalities. Heart, 84(6), pp. 582-584.
Shepherd, J., Cobbe, S.M., Ford, I. , Isles, C.G., Lorimer, A.R., Macfarlane, P.W., McKillop, J.H. and Packard, C.J. (1995) Prevention of coronary heart disease with pravastatin in men with hypercholesterolemia. New England Journal of Medicine, 333(20), pp. 1301-1308. (doi: 10.1056/NEJM199511163332001)
Book Sections
Cooper, C., Clark, E. and Macfarlane, P. (2008) Enhanced Detection of Electrode Placement/Connection Errors. In: Computers in Cardiology. IEEE: New York, pp. 89-92. ISBN 978-1-4244-3706-1
Trompet, S. et al. (2007) Genetic variation in the interleukin-10 gene promoter and risk of coronary and cerebrovascular events - The PROSPER study. In: Rattan, S. and Akman, S. (eds.) Biogerontology: Mechanisms and Interventions. Series: Annals of the New York Academy of Sciences (1100). Blackwell Publishing: Oxford, pp. 189-198. ISBN 978-1-57331-679-8 (doi: 10.1196/annals.1395.018)
Conference or Workshop Item
Morrow, A. et al. (2021) Rationale and design of the Medical Research Council Precision medicine with Zibotentan in microvascular angina (PRIZE) trial MRI sub-study. British Society of Cardiovascular Magnetic Resonance 2021 Annual Meeting, 12 October 2021. A2.1-A2. (doi: 10.1136/heartjnl-2021-BSCMR.3)
Conference Proceedings
Clark, E. and Macfarlane, P. (2018) Specificity of New Diagnostic Criteria for Left Ventricular Hypertrophy. In: Computing in Cardiology 2017, Rennes, France, 24-27 Sept 2017, (doi: 10.22489/CinC.2017.013-116)
Devine, B., Clark, E., Luo, S. and Macfarlane, P.W. (2012) Critical Values in the Uni-G Program. In: 39th Conference on Computing in Cardiology, Krakow, POLAND, SEP 09-12, 2012,
Grants
Grants and Awards listed are those received whilst working with the University of Glasgow.
- Mobile ECG screening in Black African populations in Zambia
Medical Research Council
2024 - 2024
- A randomised parallel group double blind placebo-controlled trial of low dose adjunctive alteplase during primary PCI (T-TIME)
National Institute for Health Research
2014 - 2017
- Enabling health and wellbeing among older people: capitalising on resources in deprived areas through general practice
Joint Improvement Team
2012 - 2013
- Enabling health and wellbeing among older people: capitalising on resources in deprived areas through general practice
Scottish Collaboration for Public Health Research & Policy
2012 - 2013
- Evaluation of electrocardiographic monitoring strategy to identify atrial fibrillation in patients with recent acute stroke
Chief Scientist Office
2010 - 2011
- Commonwealth Scholarship and Fellowship Plan
Commonwealth Scholarship Commission in the UK
2010 - 2010
- CPR Demonstration Software
Chest Heart and Stroke Scotland
2005 - 2005
- Relevance of inflammation sensitive pathways to stroke, coronary events and cognitive decline in the elderly in PROSPER
Chest Heart and Stroke Scotland
2004 - 2005
- The Prevention of a Progression of Asymptomatic Diabetic Arterial Disease Study: A Multi-Centre Study (POPADAD)
Medical Research Council
2004 - 2007
- A role for novel candidate pathways in cerebrovascular disease and cognitive decline in the elderly?
Stroke Association
2003 - 2005
Research datasets
2016
Macfarlane, P. (2016) Scottish Family Health Study. [Data Collection]
