Professor Rona Mackie
- Honorary Senior Research Fellow (School of Health & Wellbeing)
Publications
2017
Fang, J. et al. (2017) Functional characterization of a multi-cancer risk locus on chr5p15.33 reveals regulation of TERT by ZNF148. Nature Communications, 8, 15034. (doi: 10.1038/ncomms15034) (PMID:28447668) (PMCID:PMC5414179)
2014
Walter, F. M., Birt, L., Cavers, D., Scott, S., Emery, J., Burrows, N., Cavanagh, G., Mackie, R., Weller, D. and Campbell, C. (2014) 'This isn't what mine looked like': a qualitative study of symptom appraisal and help seeking in people recently diagnosed with melanoma. BMJ Open, 4(7), e005566. (doi: 10.1136/bmjopen-2014-005566) (PMID:25052174) (PMCID:PMC4120305)
2013
Iles, M.M. et al. (2013) A variant in FTO shows association with melanoma risk not due to BMI. Nature Genetics, 45(4), pp. 428-432. (doi: 10.1038/ng.2571)
2011
MacGregor, S. et al. (2011) Genome-wide association study identifies a new melanoma susceptibility locus at 1q21.3. Nature Genetics, 43(11), pp. 1114-1118. (doi: 10.1038/ng.958)
Barrett, J.H. et al. (2011) Genome-wide association study identifies three new melanoma susceptibility loci. Nature Genetics, 43(11), pp. 1108-1113. (doi: 10.1038/ng.959)
2010
Demenais, F. et al. (2010) Association of MC1R Variants and host phenotypes with melanoma risk in CDKN2A mutation carriers: a GenoMEL study. Journal of the National Cancer Institute, 102(20), pp. 1-16. (doi: 10.1093/jnci/djq363)
Mackie, R.M. (2010) Vitamin D in treated melanoma patients on follow up. British Journal of Dermatology, 162(3), p. 697. (doi: 10.1111/j.1365-2133.2009.09596.x) (PMID:20030636)
Marsden, J.R. et al. (2010) Revised U.K. guidelines for the management of cutaneous melanoma 2010. British Journal of Dermatology, 163(2), pp. 238-256. (doi: 10.1111/j.1365-2133.2010.09883.x)
Olsen, C.M. et al. (2010) Biologic markers of sun exposure and melanoma risk in women: Pooled case-control analysis. International Journal of Cancer, (doi: 10.1002/ijc.25691)
2009
Leachman, S.A. et al. (2009) Selection criteria for genetic assessment of patients with familial melanoma. Journal of the American Academy of Dermatology, 61(4), 677.e1-677.e14. (doi: 10.1016/j.jaad.2009.03.016)
Chang, Y.-m. et al. (2009) Sun exposure and melanoma risk at different latitudes: a pooled analysis of 5700 cases and 7216 controls. International Journal of Epidemiology, 38(3), pp. 814-830. (doi: 10.1093/ije/dyp166) (PMID:19359257) (PMCID:PMC2689397)
Bishop, D.T. et al. (2009) Genome-wide association study identifies three loci associated with melanoma risk. Nature Genetics, 41(8), pp. 920-925. (doi: 10.1038/ng.411)
Bottomley, A. et al. (2009) Adjuvant Therapy With Pegylated Interferon Alfa-2b Versus Observation in Resected Stage III Melanoma: A Phase III Randomized Controlled Trial of Health-Related Quality of Life and Symptoms by the European Organisation for Research and Treatment of Cancer Melanoma Group. Journal of Clinical Oncology, 27(18), pp. 2916-2923. (doi: 10.1200/JCO.2008.20.2069)
Chang, Y.-m. et al. (2009) A pooled analysis of melanocytic nevus phenotype and the risk of cutaneous melanoma at different latitudes. International Journal of Cancer, 124(2), pp. 420-428. (doi: 10.1002/ijc.23869)
Eggermont, A.M.M., Testori, A., Marsden, J., Hersey, P., Quirt, I., Petrella, T., Gogas, H., Mackie, R.M. and Hauschild, A. (2009) Utility of adjuvant systemic therapy in melanoma. Annals of Oncology, 20(Supple), vi30-vi34. (doi: 10.1093/annonc/mdp250)
Mackie, R. (2009) Pregnancy and the use of hormones in melanoma patients. In: Balch, C.M., Houghton, A.M., Sober, A.J., Seng-jaw, S., Atkins, M.B. and Thompson, J.F. (eds.) Cutaneous Melanoma. Quality Publishing Ltd.: St Louis, MO, p. 363. ISBN 9781576262764
Mackie, R.M., Hauschild, A. and Eggermont, A.M.M. (2009) Epidemiology of invasive cutaneous melanom. Annals of Oncology, 20(Suppl), Vi1-Vi7. (doi: 10.1093/annonc/mdp252)
2008
Eggermont, A.M.M., Suciu, S., Santinami, M., Testori, A., Kruit, W.H.J., Marsden, J., Punt, C.J.A., Salès, F., Gore, M. and Mackie, R. (2008) Adjuvant therapy with pegylated interferon alfa-2b versus observation alone in resected stage III melanoma: final results of EORTC 18991, a randomised phase III trial. Lancet, 372(9633), pp. 117-126. (doi: 10.1016/S0140-6736(08)61033-8)
Einwachter-Thompson, J. and Mackie, R.M. (2008) An evidence base for reconsidering current follow-up guidelines for patients with cutaneous melanoma less than 05mm thick at diagnosis. British Journal of Dermatology, 159(2), pp. 337-341. (doi: 10.1111/j.1365-2133.2008.08641.x)
Whiteman, D.C., Bray, C.A., Siskind, V., Green, A.C., Hole, D.J. and Mackie, R.M. (2008) Changes in the incidence of cutaneous melanoma in the west of Scotland and Queensland, Australia: hope for health promotion? European Journal of Cancer Prevention, 17(3), pp. 243-250. (doi: 10.1097/CEJ.0b013e3282b6fe3f)
2007
Elliott, B. et al. (2007) Long-Term Protective Effect of Mature DC-LAMP+ Dendritic Cell Accumulation in Sentinel Lymph Nodes Containing Micrometastatic Melanoma. Clinical Cancer Research, 13(13), pp. 3825-3830. (doi: 10.1158/1078-0432.CCR-07-0358)
Fearfield, L.A., Larkin, J.M.G., Rowe, A., A'Hern, R., Fisher, C., Francis, N., Mackie, R., McCann, B., Gore, M.E. and Bunker, C.B. (2007) Expression of p16, CD95, CD95L and Helix pomatia agglutinin in relapsing and nonrelapsing very thin melanoma. British Journal of Dermatology, 156(3), pp. 440-447. (doi: 10.1111/j.1365-2133.2006.07581.x)
Lang, J., Hayward, N., Goldgar, D., Tsao, H., Hogg, D., Palmer, J., Stark, M., Tobias, E. and Mackie, R. (2007) The m531 mutation in CDKN2A is a founder mutation that predominates in melanoma patients with Scottish ancestry. Genes, Chromosomes and Cancer, 46(3), pp. 277-287. (doi: 10.1002/gcc.20410)
Mackie, R. M., Bray, C., Vestey, J., Doherty, V., Evans, A., Thomson, D. and Nicolson, M. (2007) Melanoma incidence and mortality in Scotland 1979–2003. British Journal of Cancer, 96(11), pp. 1772-1777. (doi: 10.1038/sj.bjc.6603801)
Povey, J.E. et al. (2007) DNA repair gene polymorphisms and genetic predisposition to cutaneous melanoma. Carcinogenesis, 28(5), pp. 1087-1093. (doi: 10.1093/carcin/bgl257)
Whiteman, D.C., Bray, C.A., Siskind, V., Hole, D., Mackie, R.M. and Green, A.C. (2007) A comparison of the anatomic distribution of cutaneous melanoma in two populations with different levels of sunlight: the west of Scotland and Queensland, Australia 1982–2001. Cancer Causes and Control, 18(5), pp. 485-491. (doi: 10.1007/s10552-007-0123-1)
2006
Goldstein, A. M. et al. (2006) Features associated with germline CDKN2A mutations: a GenoMEL study of melanoma-prone families from three continents. Journal of Medical Genetics, 44(2), pp. 99-106. (doi: 10.1136/jmg.2006.043802)
2003
Mackie, R.M., Bray, C.A. and Leman, J.A. (2003) Effect of public education aimed at early diagnosis of malignant melanoma: cohort comparison study. British Medical Journal, 326, p. 367. (doi: 10.1136/bmj.326.7385.367)
2002
Mackie, R.M., Bray, C.A. and Hole, D.J. (2002) Observational study of type of surgical training and outcome of definitive surgery for primary malignant melanoma. British Medical Journal, 325, pp. 1276-1277. (doi: 10.1136/bmj.325.7375.1276)
Mackie, R.M., Bray, C.A., Hole, D.J., Morris, A., Nicolson, M., Evans, A., Doherty, V. and Vestey, J. (2002) Incidence of and survival from malignant melanoma in Scotland: an epidemiological study. Lancet, 360(9333), pp. 587-591. (doi: 10.1016/S0140-6736(02)09779-9)
Mackie, R., Fleming, C., McMahon, A. and Jarrett, P. (2002) The use of the dermatoscope to identify early melanoma using the three-colour test. British Journal of Dermatology, 146(3), pp. 481-484.
2001
Morton, C. A., Whitehurst, C., McColl, J. H. , Moore, J. V. and Mackie, R. M. (2001) Photodynamic therapy for large or multiple patches of Bowen disease and basal cell carcinoma. Archives of Dermatology, 137(3), pp. 319-324. (PMID:11255332)
1997
Mackie, R.M., Morton, C.M., Turner, S. and McColl, J. (1997) A risk factor analysis of malignant melanoma of the extremities: 175. Melanoma Research, 7(S1), S50-S50.
Morton, C.A., Turner, S., Lauder, P., McColl, J. and MacKie, R.M. (1997) Risk factor analysis of melanoma of the extremities. British Journal of Dermatology, 137(s50), pp. 21-22. (doi: 10.1111/j.1365-2133.1997.tb01879.x)
1996
Morton, C.A., Whitehurst, C., Moseley, H., McColl, J.H. , Moore, J.V. and Mackie, R.M. (1996) Comparison of photodynamic therapy with cryotherapy in the treatment of Bowen's disease. British Journal of Dermatology, 135(5), pp. 766-771. (doi: 10.1046/j.1365-2133.1996.d01-1076.x)
Articles
Fang, J. et al. (2017) Functional characterization of a multi-cancer risk locus on chr5p15.33 reveals regulation of TERT by ZNF148. Nature Communications, 8, 15034. (doi: 10.1038/ncomms15034) (PMID:28447668) (PMCID:PMC5414179)
Walter, F. M., Birt, L., Cavers, D., Scott, S., Emery, J., Burrows, N., Cavanagh, G., Mackie, R., Weller, D. and Campbell, C. (2014) 'This isn't what mine looked like': a qualitative study of symptom appraisal and help seeking in people recently diagnosed with melanoma. BMJ Open, 4(7), e005566. (doi: 10.1136/bmjopen-2014-005566) (PMID:25052174) (PMCID:PMC4120305)
Iles, M.M. et al. (2013) A variant in FTO shows association with melanoma risk not due to BMI. Nature Genetics, 45(4), pp. 428-432. (doi: 10.1038/ng.2571)
MacGregor, S. et al. (2011) Genome-wide association study identifies a new melanoma susceptibility locus at 1q21.3. Nature Genetics, 43(11), pp. 1114-1118. (doi: 10.1038/ng.958)
Barrett, J.H. et al. (2011) Genome-wide association study identifies three new melanoma susceptibility loci. Nature Genetics, 43(11), pp. 1108-1113. (doi: 10.1038/ng.959)
Demenais, F. et al. (2010) Association of MC1R Variants and host phenotypes with melanoma risk in CDKN2A mutation carriers: a GenoMEL study. Journal of the National Cancer Institute, 102(20), pp. 1-16. (doi: 10.1093/jnci/djq363)
Mackie, R.M. (2010) Vitamin D in treated melanoma patients on follow up. British Journal of Dermatology, 162(3), p. 697. (doi: 10.1111/j.1365-2133.2009.09596.x) (PMID:20030636)
Marsden, J.R. et al. (2010) Revised U.K. guidelines for the management of cutaneous melanoma 2010. British Journal of Dermatology, 163(2), pp. 238-256. (doi: 10.1111/j.1365-2133.2010.09883.x)
Olsen, C.M. et al. (2010) Biologic markers of sun exposure and melanoma risk in women: Pooled case-control analysis. International Journal of Cancer, (doi: 10.1002/ijc.25691)
Leachman, S.A. et al. (2009) Selection criteria for genetic assessment of patients with familial melanoma. Journal of the American Academy of Dermatology, 61(4), 677.e1-677.e14. (doi: 10.1016/j.jaad.2009.03.016)
Chang, Y.-m. et al. (2009) Sun exposure and melanoma risk at different latitudes: a pooled analysis of 5700 cases and 7216 controls. International Journal of Epidemiology, 38(3), pp. 814-830. (doi: 10.1093/ije/dyp166) (PMID:19359257) (PMCID:PMC2689397)
Bishop, D.T. et al. (2009) Genome-wide association study identifies three loci associated with melanoma risk. Nature Genetics, 41(8), pp. 920-925. (doi: 10.1038/ng.411)
Bottomley, A. et al. (2009) Adjuvant Therapy With Pegylated Interferon Alfa-2b Versus Observation in Resected Stage III Melanoma: A Phase III Randomized Controlled Trial of Health-Related Quality of Life and Symptoms by the European Organisation for Research and Treatment of Cancer Melanoma Group. Journal of Clinical Oncology, 27(18), pp. 2916-2923. (doi: 10.1200/JCO.2008.20.2069)
Chang, Y.-m. et al. (2009) A pooled analysis of melanocytic nevus phenotype and the risk of cutaneous melanoma at different latitudes. International Journal of Cancer, 124(2), pp. 420-428. (doi: 10.1002/ijc.23869)
Eggermont, A.M.M., Testori, A., Marsden, J., Hersey, P., Quirt, I., Petrella, T., Gogas, H., Mackie, R.M. and Hauschild, A. (2009) Utility of adjuvant systemic therapy in melanoma. Annals of Oncology, 20(Supple), vi30-vi34. (doi: 10.1093/annonc/mdp250)
Mackie, R.M., Hauschild, A. and Eggermont, A.M.M. (2009) Epidemiology of invasive cutaneous melanom. Annals of Oncology, 20(Suppl), Vi1-Vi7. (doi: 10.1093/annonc/mdp252)
Eggermont, A.M.M., Suciu, S., Santinami, M., Testori, A., Kruit, W.H.J., Marsden, J., Punt, C.J.A., Salès, F., Gore, M. and Mackie, R. (2008) Adjuvant therapy with pegylated interferon alfa-2b versus observation alone in resected stage III melanoma: final results of EORTC 18991, a randomised phase III trial. Lancet, 372(9633), pp. 117-126. (doi: 10.1016/S0140-6736(08)61033-8)
Einwachter-Thompson, J. and Mackie, R.M. (2008) An evidence base for reconsidering current follow-up guidelines for patients with cutaneous melanoma less than 05mm thick at diagnosis. British Journal of Dermatology, 159(2), pp. 337-341. (doi: 10.1111/j.1365-2133.2008.08641.x)
Whiteman, D.C., Bray, C.A., Siskind, V., Green, A.C., Hole, D.J. and Mackie, R.M. (2008) Changes in the incidence of cutaneous melanoma in the west of Scotland and Queensland, Australia: hope for health promotion? European Journal of Cancer Prevention, 17(3), pp. 243-250. (doi: 10.1097/CEJ.0b013e3282b6fe3f)
Elliott, B. et al. (2007) Long-Term Protective Effect of Mature DC-LAMP+ Dendritic Cell Accumulation in Sentinel Lymph Nodes Containing Micrometastatic Melanoma. Clinical Cancer Research, 13(13), pp. 3825-3830. (doi: 10.1158/1078-0432.CCR-07-0358)
Fearfield, L.A., Larkin, J.M.G., Rowe, A., A'Hern, R., Fisher, C., Francis, N., Mackie, R., McCann, B., Gore, M.E. and Bunker, C.B. (2007) Expression of p16, CD95, CD95L and Helix pomatia agglutinin in relapsing and nonrelapsing very thin melanoma. British Journal of Dermatology, 156(3), pp. 440-447. (doi: 10.1111/j.1365-2133.2006.07581.x)
Lang, J., Hayward, N., Goldgar, D., Tsao, H., Hogg, D., Palmer, J., Stark, M., Tobias, E. and Mackie, R. (2007) The m531 mutation in CDKN2A is a founder mutation that predominates in melanoma patients with Scottish ancestry. Genes, Chromosomes and Cancer, 46(3), pp. 277-287. (doi: 10.1002/gcc.20410)
Mackie, R. M., Bray, C., Vestey, J., Doherty, V., Evans, A., Thomson, D. and Nicolson, M. (2007) Melanoma incidence and mortality in Scotland 1979–2003. British Journal of Cancer, 96(11), pp. 1772-1777. (doi: 10.1038/sj.bjc.6603801)
Povey, J.E. et al. (2007) DNA repair gene polymorphisms and genetic predisposition to cutaneous melanoma. Carcinogenesis, 28(5), pp. 1087-1093. (doi: 10.1093/carcin/bgl257)
Whiteman, D.C., Bray, C.A., Siskind, V., Hole, D., Mackie, R.M. and Green, A.C. (2007) A comparison of the anatomic distribution of cutaneous melanoma in two populations with different levels of sunlight: the west of Scotland and Queensland, Australia 1982–2001. Cancer Causes and Control, 18(5), pp. 485-491. (doi: 10.1007/s10552-007-0123-1)
Goldstein, A. M. et al. (2006) Features associated with germline CDKN2A mutations: a GenoMEL study of melanoma-prone families from three continents. Journal of Medical Genetics, 44(2), pp. 99-106. (doi: 10.1136/jmg.2006.043802)
Mackie, R.M., Bray, C.A. and Leman, J.A. (2003) Effect of public education aimed at early diagnosis of malignant melanoma: cohort comparison study. British Medical Journal, 326, p. 367. (doi: 10.1136/bmj.326.7385.367)
Mackie, R.M., Bray, C.A. and Hole, D.J. (2002) Observational study of type of surgical training and outcome of definitive surgery for primary malignant melanoma. British Medical Journal, 325, pp. 1276-1277. (doi: 10.1136/bmj.325.7375.1276)
Mackie, R.M., Bray, C.A., Hole, D.J., Morris, A., Nicolson, M., Evans, A., Doherty, V. and Vestey, J. (2002) Incidence of and survival from malignant melanoma in Scotland: an epidemiological study. Lancet, 360(9333), pp. 587-591. (doi: 10.1016/S0140-6736(02)09779-9)
Mackie, R., Fleming, C., McMahon, A. and Jarrett, P. (2002) The use of the dermatoscope to identify early melanoma using the three-colour test. British Journal of Dermatology, 146(3), pp. 481-484.
Morton, C. A., Whitehurst, C., McColl, J. H. , Moore, J. V. and Mackie, R. M. (2001) Photodynamic therapy for large or multiple patches of Bowen disease and basal cell carcinoma. Archives of Dermatology, 137(3), pp. 319-324. (PMID:11255332)
Mackie, R.M., Morton, C.M., Turner, S. and McColl, J. (1997) A risk factor analysis of malignant melanoma of the extremities: 175. Melanoma Research, 7(S1), S50-S50.
Morton, C.A., Turner, S., Lauder, P., McColl, J. and MacKie, R.M. (1997) Risk factor analysis of melanoma of the extremities. British Journal of Dermatology, 137(s50), pp. 21-22. (doi: 10.1111/j.1365-2133.1997.tb01879.x)
Morton, C.A., Whitehurst, C., Moseley, H., McColl, J.H. , Moore, J.V. and Mackie, R.M. (1996) Comparison of photodynamic therapy with cryotherapy in the treatment of Bowen's disease. British Journal of Dermatology, 135(5), pp. 766-771. (doi: 10.1046/j.1365-2133.1996.d01-1076.x)
Book Sections
Mackie, R. (2009) Pregnancy and the use of hormones in melanoma patients. In: Balch, C.M., Houghton, A.M., Sober, A.J., Seng-jaw, S., Atkins, M.B. and Thompson, J.F. (eds.) Cutaneous Melanoma. Quality Publishing Ltd.: St Louis, MO, p. 363. ISBN 9781576262764