Number of items: 37.
2024
Brinzer, R. A. , McIntyre, J. R. , Britton, C. and Laing, R.
(2024)
The parasitic nematode Haemonchus contortus lacks molybdenum cofactor synthesis, leading to sulphite sensitivity and lethality in vitro.
International Journal for Parasitology,
(doi: 10.1016/j.ijpara.2024.11.004)
(PMID:39617094)
(Early Online Publication)
Nak-on, S., Campbell, P., Shalaby, M. M., McIntyre, J. , Antonopoulos, A., Chontananarth, T. and Laing, R.
(2024)
Development of a LAMP detection assay for Dictyocaulus viviparus Bloch, 1782 lungworm: DviLAMP.
Frontiers in Veterinary Science, 11,
1454065.
(doi: 10.3389/fvets.2024.1454065)
Campbell, P., Forbes, A., McIntyre, J. , Bartoschek, T., Devine, K., O’Neill, K., Laing, R. and Ellis, K.
(2024)
Inefficacy of ivermectin and moxidectin treatments against Dictyocaulus viviparus in dairy calves.
Veterinary Record,
(doi: 10.1002/vetr.4265)
(PMID:38845174)
(Early Online Publication)
Perez, M. , Laing, R. , Hildersley, K., McNeilly, T., Maizels, R. , Devaney, E. and Britton, C.
(2024)
A MicroRNA in the Excretory-secretory Products of Helminth Parasites Induces De-differentiation in Epithelial Cells Within Gastrointestinal Organoids.
British Society for Parasitology (BSP) Spring Meeting, Liverpool, UK, 2-4 April 2024.
(Unpublished)
Antonopoulos, A., Charvet, C. L., Maitland, K. , Doyle, S. R., Neveu, C. and Laing, R.
(2024)
Functional validation of novel levamisole resistance marker S168T in Haemonchus contortus.
International Journal for Parasitology: Drugs and Drug Resistance, 24,
100524.
(doi: 10.1016/j.ijpddr.2024.100524)
(PMID:38346379)
(PMCID:PMC10867575)
Antonopoulos, A. et al.
(2024)
Real-time single base specific detection of the Haemonchus contortus S168T variant associated with levamisole resistance using loop-primer endonuclease cleavage loop mediated isothermal amplification.
Molecular and Cellular Probes, 73,
101946.
(doi: 10.1016/j.mcp.2023.101946)
(PMID:38097144)
(PMCID:PMC10884526)
2023
Britton, C. , Laing, R. , McNeilly, T. N., Perez, M. G. , Otto, T. D. , Hildersley, K. A., Maizels, R. M. , Devaney, E. and Gillan, V.
(2023)
New technologies to study helminth development and host-parasite interactions.
International Journal for Parasitology, 53(8),
pp. 393-403.
(doi: 10.1016/j.ijpara.2022.11.012)
(PMID:36931423)
McIntyre, J. , Miskell, L., Morgan, E. R., Lovatt, F. and Laing, R.
(2023)
Moxidectin use in Scottish sheep flocks suggests a need for clearer product labelling and communication of updated SCOPS guidelines.
Veterinary Record, 192(2),
e2083.
(doi: 10.1002/vetr.2083)
(PMID:36030372)
(PMCID:PMC10087414)
2022
Antonopoulos, A., Doyle, S. R., Bartley, D. J., Morrison, A. A., Kaplan, R., Howell, S., Neveu, C., Busin, V. , Devaney, E. and Laing, R.
(2022)
Allele specific PCR for a major marker of levamisole resistance in Haemonchus contortus.
International Journal for Parasitology: Drugs and Drug Resistance, 20,
pp. 17-26.
(doi: 10.1016/j.ijpddr.2022.08.001)
(PMID:35970104)
(PMCID:PMC9399269)
Doyle, S. R. et al.
(2022)
Genomic landscape of drug response reveals mediators of anthelmintic resistance.
Cell Reports, 41(3),
111522.
(doi: 10.1016/j.celrep.2022.111522)
(PMID:36261007)
(PMCID:PMC9597552)
Wit, J. et al.
(2022)
Genomic signatures of selection associated with benzimidazole drug treatments in Haemonchus contortus field populations.
International Journal for Parasitology, 52(10),
pp. 677-689.
(doi: 10.1016/j.ijpara.2022.07.004)
(PMID:36113620)
Laing, R. et al.
(2022)
Transcriptomic analyses implicate neuronal plasticity and chloride homeostasis in ivermectin resistance and response to treatment in a parasitic nematode.
PLoS Pathogens, 18(6),
e1010545.
(doi: 10.1371/journal.ppat.1010545)
(PMID:35696434)
(PMCID:PMC9232149)
2020
Doyle, S. R. et al.
(2020)
Genomic and transcriptomic variation defines the chromosome-scale assembly of Haemonchus contortus, a model gastrointestinal worm.
Communications Biology, 3,
656.
(doi: 10.1038/s42003-020-01377-3)
(PMID:33168940)
(PMCID:PMC7652881)
Britton, C. , Laing, R. and Devaney, E.
(2020)
Small RNAs in parasitic nematodes - forms and functions.
Parasitology, 147(8),
pp. 855-864.
(doi: 10.1017/S0031182019001689)
(PMID:31843030)
(PMCID:PMC7284814)
2019
Antonopoulos, A., Busin, V. , Laing, R. and Devaney, E.
(2019)
Levamisole Resistance Markers in Haemonchus Contortus.
BAVP Winter Meeting 2019, Moredun Research Institute, Edinburgh, 5-6 Dec 2019.
Turnbull, F. , Devaney, E. , Morrison, A. A., Laing, R. and Bartley, D. J.
(2019)
Genotypic characterisation of monepantel resistance in historical and newly derived field strains of Teladorsagia circumcincta.
International Journal for Parasitology: Drugs and Drug Resistance, 11,
pp. 59-69.
(doi: 10.1016/j.ijpddr.2019.10.002)
(PMID:31622822)
(PMCID:PMC6796645)
Rezansoff, A. M. et al.
(2019)
The confounding effects of high genetic diversity on the determination and interpretation of differential gene expression analysis in the parasitic nematode Haemonchus contortus.
International Journal for Parasitology, 49(11),
pp. 847-858.
(doi: 10.1016/j.ijpara.2019.05.012)
(PMID:31525371)
Doyle, S. R. et al.
(2019)
Evaluation of DNA extraction methods on individual helminth egg and larval stages for whole-genome sequencing.
Frontiers in Genetics, 10,
826.
(doi: 10.3389/fgene.2019.00826)
(PMID:31616465)
(PMCID:PMC6764475)
Hodgkinson, J. E. et al.
(2019)
Refugia and anthelmintic resistance: concepts and challenges.
International Journal for Parasitology, 10,
pp. 51-57.
(doi: 10.1016/j.ijpddr.2019.05.001)
(PMID:31125837)
(PMCID:PMC6531808)
Doyle, S. R. et al.
(2019)
Population genomic and evolutionary modelling analyses reveal a single major QTL for ivermectin drug resistance in the pathogenic nematode, Haemonchus contortus.
BMC Genomics, 20,
p. 218.
(doi: 10.1186/s12864-019-5592-6)
(PMID:30876405)
(PMCID:PMC6420744)
Marks, N. D. et al.
(2019)
Profiling microRNAs through development of the parasitic nematode Haemonchus identifies nematode-specific miRNAs that suppress larval development.
Scientific Reports, 9,
17594.
(doi: 10.1038/s41598-019-54154-6)
(PMID:31772378)
(PMCID:PMC6879476)
2018
Matoušková, P. et al.
(2018)
UDP-glycosyltransferase family in Haemonchus contortus: Phylogenetic analysis, constitutive expression, sex-differences and resistance-related differences.
International Journal for Parasitology: Drugs and Drug Resistance, 8(3),
pp. 420-429.
(doi: 10.1016/j.ijpddr.2018.09.005)
(PMID:30293057)
(PMCID:PMC6174829)
McIntyre, J., Hamer, K., Morrison, A. A., Bartley, D. J., Sargison, N., Devaney, E. and Laing, R.
(2018)
Hidden in plain sight - multiple resistant species within a strongyle community.
Veterinary Parasitology, 258,
pp. 79-87.
(doi: 10.1016/j.vetpar.2018.06.012)
(PMCID:PMC6052248)
Sallé, G. et al.
(2018)
Transcriptomic profiling of nematode parasites surviving vaccine exposure.
International Journal for Parasitology, 48(5),
pp. 395-402.
(doi: 10.1016/j.ijpara.2018.01.004)
(PMID:29534987)
(PMCID:PMC5909036)
Doyle, S. R. et al.
(2018)
A genome resequencing-based genetic map reveals the recombination landscape of an outbred parasitic nematode in the presence of polyploidy and polyandry.
Genome Biology and Evolution, 10(2),
pp. 396-409.
(doi: 10.1093/gbe/evx269)
(PMID:29267942)
(PMCID:PMC5793844)
2017
Gillan, V. et al.
(2017)
Increased expression of a microRNA correlates with anthelmintic resistance in parasitic nematodes.
Frontiers in Cellular and Infection Microbiology, 7,
452.
(doi: 10.3389/fcimb.2017.00452)
(PMID:29209592)
(PMCID:PMC5701612)
Laing, R. , Gillan, V. and Devaney, E.
(2017)
Ivermectin - old drug, new tricks?
Trends in Parasitology, 33(6),
pp. 463-472.
(doi: 10.1016/j.pt.2017.02.004)
(PMID:28285851)
(PMCID:PMC5446326)
2016
Laing, R. , Maitland, K. , Lecova, L., Skuce, P. J., Tait, A. and Devaney, E.
(2016)
Analysis of putative resistance gene loci in UK field populations of Haemonchus contortus after six years of macrocyclic lactone use.
International Journal for Parasitology, 46(10),
pp. 621-630.
(doi: 10.1016/j.ijpara.2016.03.010)
(PMID:27179994)
(PMCID:PMC5011429)
Rezansoff, A. M., Laing, R. and Gilleard, J. S.
(2016)
Evidence from two independent backcross experiments supports genetic linkage of microsatellite Hcms8a20, but not other candidate loci, to a major ivermectin resistance locus in Haemonchus contortus.
International Journal for Parasitology, 46(10),
pp. 653-661.
(doi: 10.1016/j.ijpara.2016.04.007)
(PMID:27216082)
Laing, R. , Martinelli, A., Tracey, A., Holroyd, N., Gilleard, J.S. and Cotton, J.A.
(2016)
Haemonchus contortus: genome structure, organization and comparative genomics.
In: Gasser, R. B. and von Samson-Himmelstjerna, G. (eds.)
Haemonchus contortus and Haemonchosis – Past, Present and Future Trends.
Series: Advances in parasitology (93).
Elsevier: Amsterdam, pp. 569-598.
ISBN 9780128103951
(doi: 10.1016/bs.apar.2016.02.016)
2015
Laing, R. , Bartley, D. J., Morrison, A. A., Rezansoff, A., Martinelli, A., Laing, S. T. and Gilleard, J. S.
(2015)
The cytochrome P450 family in the parasitic nematode Haemonchus contortus.
International Journal for Parasitology, 45(4),
pp. 243-251.
(doi: 10.1016/j.ijpara.2014.12.001)
(PMID:25558056)
(PMCID:PMC4365919)
Lecova, L., Růžičková, M., Laing, R. , Vogel, H., Szotáková, B., Prchal, L., Lamka, J., Vokřál, I., Skálová, L. and Matoušková, P.
(2015)
Reliable reference gene selection for quantitative real time PCR in Haemonchus contortus.
Molecular and Biochemical Parasitology, 201(2),
pp. 123-127.
(doi: 10.1016/j.molbiopara.2015.08.001)
(PMID:26255779)
2013
Laing, R. et al.
(2013)
The genome and transcriptome of haemonchus contortus, a key model parasite for drug and vaccine discovery.
Genome Biology, 14(8),
R88.
(doi: 10.1186/gb-2013-14-8-r88)
(PMID:23985316)
(PMCID:PMC4054779)
Saunders, G. I., Wasmuth, J. D., Beech, R., Laing, R. , Hunt, M., Naghra, H., Cotton, J. A. , Berriman, M., Britton, C. and Gilleard, J. S.
(2013)
Characterization and comparative analysis of the complete Haemonchus contortus β-tubulin gene family and implications for benzimidazole resistance in strongylid nematodes.
International Journal for Parasitology, 43(6),
pp. 465-475.
(doi: 10.1016/j.ijpara.2012.12.011)
(PMID:23416426)
2012
Laing, S.T., Ivens, A., Butler, V., Ravikumar, S.P., Laing, R. , Woods, D.J. and Gilleard, J.S.
(2012)
The transcriptional response of Caenorhabditis elegans to ivermectin exposure identifies novel genes involved in the response to reduced food intake.
PLoS ONE, 7(2),
e31367.
(doi: 10.1371/journal.pone.0031367)
(PMID:22348077)
(PMCID:PMC3279368)
2011
Laing, R. et al.
(2011)
Annotation of two large contiguous regions from the Haemonchus contortus genome using RNA-seq and comparative analysis with Caenorhabditis elegans.
PLoS ONE, 6(8),
e23216.
(doi: 10.1371/journal.pone.0023216)
(PMID:21858033)
(PMCID:PMC3156134)
2010
Laing, S., Ivens, A., Laing, R. , Ravikumar, S., Butler, V., Woods, D.J. and Gilleard, J.S.
(2010)
Characterization of the xenobiotic response of Caenorhabditis elegans to the anthelmintic drug albendazole and the identification of novel drug glucoside metabolites.
Biochemical Journal, 432(3),
pp. 505-514.
(doi: 10.1042/BJ20101346)
This list was generated on Sat Dec 21 17:19:11 2024 GMT.