University of Glasgow - Research - Research units A-Z - Glasgow Tissue Research Facility - Publications

Publications

Gray V, Briggs S, Palles C, Jaeger E, Iveson T, Kerr R, Saunders MP, Paul J, Harkin A, McQueen J, Summers MG, Johnstone E, Wang H, Gatcombe L, Maughan TS, Kaplan R, Escott-Price V, Al-Tassan NA, Meyer BF, Wakil SM, Houlston RS, Cheadle JP, Tomlinson I, Church DN. Pattern Recognition Receptor Polymorphisms as Predictors of Oxaliplatin Benefit in Colorectal Cancer. J Natl Cancer Inst. 2019 Aug 1;111(8):828-836. doi: 10.1093/jnci/djy215. PMID: 30649440; PMCID: PMC6695319.
Alexander PG, Roseweir AK, Pennel KAF, van Wyk HC, Powell AGMT, McMillan DC, Horgan PG, Kelly C, Hay J, Sansom O, Harkin A, Roxburgh CSD, Graham J, Church DN, Tomlinson I, Saunders M, Iveson TJ, Edwards J, Park JH. The Glasgow Microenvironment Score associates with prognosis and adjuvant chemotherapy response in colorectal cancer. Br J Cancer. 2021 Feb;124(4):786-796. doi: 10.1038/s41416-020-01168-x. Epub 2020 Nov 23. PMID: 33223535.
Al-Badran, S. S.F. et al. (2021) Relationship between immune checkpoint proteins, tumour microenvironment characteristics, and prognosis in primary operable colorectal cancer. Journal of Pathology: Clinical Research, 7(2), pp. 121-134. (doi: 10.1002/cjp2.193) (PMID:33338327)
Knight, J. R.P. et al. (2020) MNK inhibition sensitizes KRAS-mutant colorectal cancer to mTORC1 inhibition by reducing eIF4E phosphorylation and c-MYC expression. Cancer Discovery, (doi: 10.1158/2159-8290.CD-20-0652) (PMID:33328217) (Early Online Publication)
McAllister, M. J., McCall, P., Dickson, A., Underwood, M. A., Andersen, D., Holmes, E., Market, E., Leung, H. Y. and Edwards, J.(2020) Androgen receptor phosphorylation at serine 81 and serine 213 in castrate-resistant prostate cancer. Prostate Cancer and Prostatic Diseases, 23(4), pp. 596-606. (doi: 10.1038/s41391-020-0235-1) (PMID:32358577)
McAllister, M., Constancio, V., Patek, S., Gan, H., Bailey, P. , Wheadon, H. , Underwood, M., Leung, H. and Edwards, J. (2020)Inflammatory infiltration is associated with AR expression and poor prognosis in hormone naïve prostate cancer. Prostate, 80(15), pp. 1353-1364. (doi: 10.1002/pros.24064) (PMID:32846021)
Montes, M. et al. (2020) Determining the prognostic significance of IKKα in prostate cancer. Prostate, 80(14), pp. 1188-1202. (doi: 10.1002/pros.24045) (PMID:33258506)
Roseweir, A. K. et al. (2020) Histological phenotypic subtypes predict recurrence risk and response to adjuvant chemotherapy in patients with stage III colorectal cancer. Journal of Pathology: Clinical Research, 6(4), pp. 283-296. (doi: 10.1002/cjp2.171)(PMID:32401426) (PMCID:PMC7578335)
Torrente, L. et al. (2020) High NRF2 levels correlate with poor prognosis in colorectal cancer patients and with sensitivity to the kinase inhibitor AT9283 in vitro. Biomolecules, 10(10), 1365. (doi: 10.3390/biom10101365) (PMID:32992842)(PMCID:PMC7600603)
Rooney, N. et al. (2020) RUNX1 is a driver of renal cell carcinoma correlating with clinical outcome. Cancer Research, 80(11), pp. 2325-2339. (doi: 10.1158/0008-5472.CAN-19-3870) (PMID:32156779)
Park, J. H. , van Wyk, H. , McMillan, D. C. , Edwards, J. , Orange, C., Horgan, P. G. and Roxburgh, C. S.D. (2019) Pre-operative, biopsy-based assessment of the tumour microenvironment in patients with primary operable colorectal cancer. Journal of Pathology: Clinical Research, 6(1), pp. 30-39. (doi: 10.1002/cjp2.143) (PMID:31486287) (PMCID:PMC6966701)
Andisha, N. M., McMillan, D. C. , Gujam, F. J.A., Roseweir, A. and Edwards, J. (2019) The relationship between phosphorylation status of focal adhesion kinases, molecular subtypes, tumour microenvironment and survival in patients with primary operable ductal breast cancer. Cellular Signalling, 60, pp. 91-99. (doi: 10.1016/j.cellsig.2019.04.006) (PMID:30981841)
Roseweir, A. K. , Clark, J., McSorley, S. T. , vanWyk, H. C. , Quinn, J. A. , Horgan, P. G. , McMillan, D. C. , Park, J. H. and Edwards, J. (2019) The association between markers of tumour cell metabolism, the tumour microenvironment and outcomes in patients with colorectal cancer. International Journal of Cancer, 144(9), pp. 2320-2329. (doi: 10.1002/ijc.32045) (PMID:30521130)
Roseweir, A. K. , Powell, A. G.M.T., Horstman, S. L., Inthagard, J., Park, J. A. , McMillan, D. C. , Horgan, P. G. and Edwards, J.(2019) Src family kinases, HCK and FGR, associate with local inflammation and tumour progression in colorectal cancer. Cellular Signalling, 56, pp. 15-22. (doi: 10.1016/j.cellsig.2019.01.007) (PMID:30684564)
Roseweir, A.K. et al. (2019) A novel tumor-based epithelial-to-mesenchymal transition score that associates with prognosis and metastasis in patients with stage II/III colorectal cancer. International Journal of Cancer, 144(1), pp. 150-159. (doi: 10.1002/ijc.31739) (PMID:29992570)
Van Wyk, H. , Roseweir, A. , Alexander, P. , Park, J. H. , Horgan, P. , McMillan, D. and Edwards, J. (2019) The relationship between tumour budding, tumour microenvironment and survival in patients with primary operable colorectal cancer. Annals of Surgical Oncology, 26, pp. 4397-4404. (doi: 10.1245/s10434-019-07931-6) (PMID:31605345) (PMCID:PMC6863941)
Roseweir, A. K. , McMillan, D. C. and Edwards, J. (2018) Reply to comment of "ERK and p38MAPK combine to improve survival in patients with BRAF mutant colorectal cancer". British Journal of Cancer, 119(7), p. 909. (doi: 10.1038/s41416-018-0275-7)(PMID:30297771)
Lua, J., Qayyum, T., Edwards, J. and Roseweir, A. K. (2018) The prognostic role of the non-canonical nuclear factor-kappa B pathway in renal cell carcinoma patients. Urologia Internationalis, 101(2), pp. 190-196. (doi: 10.1159/000489816)(PMID:30089311)
Gujam, F., Dickson, K., McCall, P., McMillan, D. and Edwards, J. (2018) The relationship between androgen receptor, components of tumour microenvironment and survival in breast cancer molecular subtypes. Cancer Therapy and Oncology, 11(3), 555814.
Roseweir, A. K. , Halcrow, E. S., Chichilo, S., Powell, A. G.M.T., McMillan, D. C. , Horgan, P. G. and Edwards, J. (2018) ERK and p38MAPK combine to improve survival in patients with BRAF mutant colorectal cancer. British Journal of Cancer, 119, pp. 323-329. (doi: 10.1038/s41416-018-0174-y) (PMID:29988110)
Sierra Gonzalez, P. et al. (2018) Mannose impairs tumour growth and enhances chemotherapy. Nature, 563, pp. 719-723. (doi: 10.1038/s41586-018-0729-3) (PMID:30464341)
Roseweir, A. K. , McCall, P., Scott, A., Liew, B., Lim, Z., Mallon, E. A. and Edwards, J. (2017) Phosphorylation of androgen receptors at serine 515 is a potential prognostic marker for triple negative breast cancer. Oncotarget, 8(23), pp. 37172-37185.(doi: 10.18632/oncotarget.16420) (PMID:28415597) (PMCID:PMC5514900)
Bennett, L., Mallon, E. A., Horgan, P. G. , Paul, A., McMillan, D. C. and Edwards, J. (2017) The relationship between members of the canonical NF-KB pathway, components of tumour microenvironment and survival in patients with invasive ductal breast cancer. Oncotarget, 8(20), pp. 33002-33013. (doi: 10.18632/oncotarget.16031) (PMID:28423692)
Bennett, L., Quinn, J. , McCall, P., Mallon, E. A., Horgan, P. G. , McMillan, D. C. , Paul, A. and Edwards, J. (2017) High IKKα expression is associated with reduced time to recurrence and cancer specific survival in oestrogen receptor (ER)-positive breast cancer. International Journal of Cancer, 140(7), pp. 1633-1644. (doi: 10.1002/ijc.30578) (PMID:28006839)
Cheng, K. K.W., Dickson, A., Gujam, F. J.A., McMillan, D. C. and Edwards, J. (2017) The relationship between oestrogen receptor-alpha phosphorylation and the tumour microenvironment in patients with primary operable ductal breast cancer. Histopathology, 70(5), pp. 782-797. (doi: 10.1111/his.13134) (PMID:27891654)
Park, J. H. , Van Wyk, H. C., McMillan, D. C. , Quinn, J. A. , Clark, J., Roxburgh, C. , Horgan, P. G. and Edwards, J. (2017) Signal transduction and activator of transcription-3 (STAT3) in patients with colorectal cancer: associations with the phenotypic features of the tumour and host. Clinical Cancer Research, 23(7), pp. 1698-1709. (doi: 10.1158/1078-0432.CCR-16-1416)(PMID:27678454)
Pritchard, J. J.G., Hamilton, G., Hurst, C. D., Fraser, S., Orange, C., Knowles, M. A., Jones, R. J. , Leung, H. Y. and Iwata, T. (2020) Monitoring of urothelial cancer disease status after treatment by digital droplet PCR liquid biopsy assays. Urologic Oncology: Seminars and Original Investigations, 38(9), 731.e1-737.e10. (doi: 10.1016/j.urolonc.2020.05.012) (PMID:32532529)