Underpinning Bioscience Discovery
Designing signalling bias: benchmarking AI methods for de novo peptide agonist design at the galanin GAL2 receptor
Mechanisms of organismal resilience to chemical stress: a Drosophila model of ageing, regeneration and recovery.
Profiling complex wound biofilms using surface enhanced Raman scattering (SERS) to inform antimicrobial resistance strategies
Unraveling the cellular and molecular mechanisms of thyroid-hormone dependent intestinal remodeling in vertebrates
Defining Neuroimmune Mechanisms of Chronic Pain in the Canine Spinal Cord Using Spatial Transcriptomics
Dissecting the molecular aetiology of myeloid neoplasia using targeted protein degradation and chemoproteomics
A chemicaL biology approach to Identify Novel Substrates of the cell surface protein ACYL transferase ZDHHC5
Can bio-based additives enhance microbial recruitment and degradation of plastics without compromising performance?
Exploring how mechanical stimulation regulates mature osteoblasts to underpin future therapy development
Find out more about the project
Enzyme-responsive self-assembling antimicrobial peptides for the eradication of biofilm-associated persister cells in diabetic foot ulcer infection
Emergency exit – how the parasite mitoribosome exit tunnel can be specifically inhibited as basis for developing new anti-parasitic drugs
CASE Projects
Defining the impact of meat-derived nitrite metabolites on mammalian metabolic homeostasis and intestinal epithelial adaptation
Regulation of Macromolecular Condensate Dynamics Through G3BP1‑Mediated Nucleation and Staufen1‑Mediated Dissolution
