Underpinning Bioscience Discovery

Innovative Strategies to Treat Bovine Mastitis: Design and Mode of Action Investigation of Strathclyde-Minor Groove Binders

Data Generation and Analysis to Predict Ligand Signaling Pathways in Anti-inflammatory GPR84 employing Pharmacology, Computer Simulations and Machine Learning
Investigating the antimicrobial potential of Scottish seagrass microbiomes

Imaging into the brain using single-pixel techniques for multi-dimensional investigations
Investigating the evolutionary conservation of organismal death mechanisms in ectotherms

Unraveling the cellular and molecular mechanisms of postembryonic intestine remodeling
Exploring the mechanical response of mature osteoblasts to underpin future therapy development
Understanding the immunoprotective function of the adenosine deaminase acting on RNA-2

Protac-mediated phospholamban ablation as a therapeutic approach for vascular dysfunction and heart failure
Leveraging novel epigenetic and biotelemetry tools to assess the impact of sleep disruption on biological aging in the wild
Unravelling crosstalk in the bone marrow microenvironment during ontogeny

Hippocampal-thalamic interactions in sleep and memory
Exploring enzyme-substrate S-acylation networks and their role in cell physiology
Find out more about the project
Mechanotransduction and Viscoelastic Characterization of Multicellular Spheroids: Integrating Microfluidic and i-Rheo-Optical Assays
A chemical biology approach to identify novel substrates of the cell survace protein acyl transerase ZDHHC5 A
Investigating the mechanisms of neuron-glia signalling controlling brain energetics in healthy and ageing brains
Demystifying the role of dementia and cancer in quality of life of ageing population
Understanding the impact of biosolids fertiliser on antimicrobial resistance and animal health
The structural and molecular basis of substrate specificity of the thioesterases APT1 and APT2
Breaking the Code of Inflammation: How Cells Sense and Respond to Physical Signals
Identification and characterisation of the ubiquitin ligases that regulate CIZ1 proteostasis and evaluation of their role in cell cycle regulation
Investigation of the role of RNA:DNA hybrids in telomere stability and differentiation of hematopoietic stem cells
Examining the impacts of aging and the microbiome on the physiology of geothermally adapted populations of stickleback
CASE Projects
