Prevalence and patterns of multimorbidity in patients with cancer

Supervisors: 

Dr Jennifer Lees, School of Cardiovascular & Metabolic Health (University of Glasgow) 

Prof Richard Wilson, School of Cancer Sciences (University of Glasgow)

Prof Ninian N Lang, School of Cardiovascular & Metabolic Health (University of Glasgow) 

Prof Patrick Mark, School of Cardiovascular & Metabolic Health (University of Glasgow) 

Summary: 

Since the 1970s, cancer survival has doubled, after an explosion in the availability of targeted therapies. Both cancer and targeted therapies are strongly linked to the development of cardiometabolic diseases (including kidney and cardiovascular disease and diabetes), which likely develop in parallel and substantially impact on morbidity and mortality. Despite being a high-risk population, monitoring and primary prevention of cardiometabolic multimorbidity is not performed routinely among people diagnosed with cancer.

This project will harness the power of routine care data and individual participant-level trial data to explore the prevalence and accrual of cardiometabolic multimorbidity among patients diagnosed with cancer, exploring the impact of inequalities in monitoring and treatment, and identifying targeted areas for improvement. Through a custom-designed prospective cohort study, the successful applicant will assess the utility of routine monitoring for detection and prevention of cardiometabolic multimorbidity among people with cancer.

Working with experts in the School of Cardiovascular and Metabolic Health and the School of Cancer Sciences at the University of Glasgow, the successful applicant will gain expertise in epidemiology, coding, and clinical research, and will benefit from access to a range of expertise from established national and international collaborators.