Qiyun Peng

2227323p@student.gla.ac.uk

Advanced Research Centre, University of Glasgow, 11 Chapel Lane, Glasgow G11 6EW 

ORCID iDhttps://orcid.org/0000-0003-2496-7710

Research title: Real-time imaging and spectroscopic analysis for biomedical diagnosis

Research Summary

Traditional methods for cell identification and tracking in biomedical diagnosis often require immunostaining or fluorescence labelling. These processes are not only lengthy but often compromise cell viability. Raman spectroscopy is a non-invasive, label-free method for analysis of cells and tissue. A Raman spectrum consists of thousands of Raman "fingerprints" that reveal the whole chemical composition of the sample. In recent years, Raman spectroscopy has been rapidly implemented in clinical diagnosis, biology, and life science. However, Raman signals are inherently weak and require long-time acquisition. This makes it highly challenging to collecting weak signals from living cells for fast spectroscopic analysis in high throughput processes (e.g., sorting) and for real-time study of dynamic changes in cells. Furthermore, the diversity and uncertainty of biological information also impose significant challenges to signal processing. The project will focus on weak Raman signal processing algorithm design, biological experiments verification and platform improvements.

Publications

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Jump to: 2024
Number of items: 1.

2024

Peng, Q., Dong, Y., Chen, Y., Glidle, A., Kong, L., Yin, H. , Xu, J. and Yang, K. (2024) Rapid profiling of fish cell nitrogen metabolism with single-cell Raman spectroscopy: unveiling enzyme’s role in ammonia detoxification. Talanta, (doi: 10.1016/j.talanta.2024.126389) (Early Online Publication)

This list was generated on Wed Jul 17 05:19:39 2024 BST.
Jump to: Articles
Number of items: 1.

Articles

Peng, Q., Dong, Y., Chen, Y., Glidle, A., Kong, L., Yin, H. , Xu, J. and Yang, K. (2024) Rapid profiling of fish cell nitrogen metabolism with single-cell Raman spectroscopy: unveiling enzyme’s role in ammonia detoxification. Talanta, (doi: 10.1016/j.talanta.2024.126389) (Early Online Publication)

This list was generated on Wed Jul 17 05:19:39 2024 BST.

Additional Information

Third place in 2023 Scottish student sports - table tennis (single and double)