Matthew Arnold
email: m.arnold.1@research.gla.ac.uk
https://orcid.org/0000-0003-1639-9223
Research title: Assessing and predicting viral diversity and cross-species transmission at the global and metapopulation scales
Research Summary
Current Work
For up-to-date publications and research interests, see my website.
I am currently working on a project assessing the diversity, composition and sharing of viral communities in marine mammals, with samples from the Scottish Marine Animal Strandings Scheme and data from public databases.
I am also interested in the ways viruses adapt to host species and how we can use signals that this imprints in viral genomes better to understand the patterns underlying host tropism. My main work is concerned with leveraging signals in viral protein seqeunces to build machine learning models of reservoir host for diverse viruses, with the intention of uncovering common priniciples for host adaptation. Alongside this, I am part of ongoing projects to investigate host tropism in rabies using structural biology and to promote conversations around One Health.
Past Work
Compuataional structural biology:
I was fortunate to work with Professor Alain Kohl using computational structure inference to explore new structure space in the field of arthropod viral immunity.
Structural virology:
As part of the Bullough group at the University of Sheffield, I worked on a project with Dr Jason Wilson investigating the mechanism of action of a C. difficile bacteriophage.
Research datasets
Additional Information
Website
Education
2019-2020: MSc in Biological Imaging - Department of Physics and Astronomy, University of Sheffield
2014- 2017: BSc in Biochemistry - Department of Molecular Biology and Biotechnology, University of Sheffield
Professional Bodies
Microbiology Society
