Clinical trials to accelerate research into treating chronic kidney disease will be strengthened as a result of a new partnership between the Scottish Government, academia and industry.

NHS Scotland, AstraZeneca and the Universities of Glasgow and Dundee will work together on new medicines to slow the progression of chronic kidney disease, reducing the risk that patients might need dialysis or kidney transplantation.

The partnership will allow for development of new treatments to treat chronic kidney disease, build infrastructure and enhance expertise in renal clinical trial delivery in Scotland with the key aim of improving patient outcomes.

Illustration of kidney organs highlighted in red

Preventing progression of the disease allows people to live longer, better lives, free from other consequences of the condition such as heart failure, cardiovascular disease and stroke. This allows people to work, contribute to their communities and economy, while reducing pressure on the NHS.

Cabinet Secretary for Health and Social Care, Neil Gray, said: “This project’s ‘triple helix’ approach is a shining example of how collaboration between the NHS, Scottish Government, academia and industry can accelerate health studies. As we navigate the complex issue of chronic kidney disease, our commitment to patient-centred research remains unwavering.

“Together we can advance targeted studies into medicines that slow progression of the disease and reduce the need for dialysis or transplantation, strengthen our workforce through dedicated research fellows and specialised training, provide greater opportunities for patients, and enable Scotland to attract and deliver more innovative trials.”

Professor Paddy Mark, Professor of Nephrology at the University of Glasgow and Honorary Consultant Nephrologist, Queen Elizabeth University Hospital, said: “I am delighted to be part of this important new partnership, bringing together research, the NHS and industry. This collaboration will make Scotland a centre of global excellence for kidney clinical trials, bringing new therapies and treatment options to people with chronic kidney disease across the country.

“For too many years, we have had no new treatments to prevent kidney failure. Our partners, AstraZeneca, have been at the forefront of breakthroughs in treating chronic kidney disease and there is still much work to be done. We hope the partnership will lead to improved outcomes for people with kidney disease in Scotland and globally.”

Professor Dame Anna Dominiczak, Chief Scientist (Health) at Scottish Government said: “I welcome this partnership with AstraZeneca which builds upon the excellent research infrastructure and expertise we have in Scotland, to drive the development of new treatments for chronic kidney disease. We must all work together to improve the outcomes and life circumstances for people living with kidney disease; and this partnership enables the fusion of medical expertise, knowledge, and insight from across NHS, academia, and industry.”

Tom Keith-Roach, AstraZeneca UK President, said: "Scotland is setting a bold ambition to change the trajectory of chronic kidney disease. We are thrilled to invest in a partnership with the University of Glasgow, the University of Dundee, and the Scottish Government to speed up the study of three potential new combination medicines to treat this disease. The triple helix of industry, academia and NHS Scotland is a powerful force with the potential to transform care and outcomes for people. Furthermore, we believe Scotland is well placed to collaborate with AstraZeneca to shape our research on the world stage across a number of disease areas and attract investment to the country’s thriving Life Science sector."


Enquiries: ali.howard@glasgow.ac.uk or elizabeth.mcmeekin@glasgow.ac.uk

First published: 26 July 2024