Dr Elspeth Elliott
- Head of Academic Consultancy Services (Innovation, Entrepreneurship & Engagement)
telephone:
01413303879
email:
Elspeth.Elliott@glasgow.ac.uk
Rsio, Room 449, Number 11 The Square, Glasgow, G12 8qq
Publications
2024
Loughrey, C. et al. (2024) A novel ryanodine receptor 2 inhibitor, M201-A, enhances natriuresis, renal function and lusi-inotropic action: Pre-clinical and phase I study. British Journal of Pharmacology, 181(18), pp. 3401-3419. (doi: 10.1111/bph.16379) (PMID:38773354)
2022
He, W. et al. (2022) Inhibition of myocardial cathepsin-L release during reperfusion following myocardial infarction improves cardiac function and reduces infarct size. Cardiovascular Research, 118(6), pp. 1535-1547. (doi: 10.1093/cvr/cvab204) (PMID:34132807)
2018
McCarroll, C. S. et al. (2018) Runx1 deficiency protects against adverse cardiac remodeling after myocardial infarction. Circulation, 137(1), pp. 57-70. (doi: 10.1161/CIRCULATIONAHA.117.028911) (PMID:29030345) (PMCID:PMC5757664)
2012
Elliott, E.B., Kelly, A., Smith, G.L. and Loughrey, C.M. (2012) Isolated rabbit working heart function during progressive inhibition of myocardial SERCA activity. Circulation Research, 110(12), pp. 1618-1627. (doi: 10.1161/CIRCRESAHA.111.262337)
Kelly, A., Elliott, E.B., Matsuda, R., Kaneko, N., Smith, G.L. and Loughrey, C.M. (2012) The effect of K201 on isolated working rabbit heart mechanical function during pharmacologically-induced Ca2+ overload. British Journal of Pharmacology, 165(4b), pp. 1068-1083. (doi: 10.1111/j.1476-5381.2011.01531.x)
2011
Currie, S., Elliott, E.B., Smith, G.L. and Loughrey, C.M. (2011) Two candidates at the heart of dysfunction: The ryanodine receptor and calcium/calmodulin protein kinase II as potential targets for therapeutic intervention—An in vivo perspective. Pharmacology and Therapeutics, 131(2), pp. 204-220. (doi: 10.1016/j.pharmthera.2011.02.006)
Elliott, E.B., Hasumi, H., Otani, N., Matsuda, T., Matsuda, R., Kaneko, N., Smith, G.L. and Loughrey, C.M. (2011) K201 (JTV-519) alters the spatiotemporal properties of diastolic Ca2+ release and the associated diastolic contraction during β-adrenergic stimulation in rat ventricular cardiomyocytes. Basic Research in Cardiology, 106(6), pp. 1009-1022. (doi: 10.1007/s00395-011-0218-4)
2006
Smith, G.L., Elliott, E.B., Kettlewell, S., Currie, S. and Quinn, F.R. (2006) Na+/Ca2+ Exchanger Expression and Function in a Rabbit Model of Myocardial Infarction. Journal of Cardiovascular Electrophysiology, 17(s1), S57-S63. (doi: 10.1111/j.1540-8167.2006.00384.x)
2004
Teucher, N. et al. (2004) Excessive sarcoplasmic/endoplasmic reticulum Ca2+-ATPase expression causes increased sarcoplasmic reticulum Ca2+ uptake but decreases myocyte shortening. Circulation, 110(23), pp. 3553-3559. (doi: 10.1161/01.CIR.0000145161.48545.B3)
Articles
Loughrey, C. et al. (2024) A novel ryanodine receptor 2 inhibitor, M201-A, enhances natriuresis, renal function and lusi-inotropic action: Pre-clinical and phase I study. British Journal of Pharmacology, 181(18), pp. 3401-3419. (doi: 10.1111/bph.16379) (PMID:38773354)
He, W. et al. (2022) Inhibition of myocardial cathepsin-L release during reperfusion following myocardial infarction improves cardiac function and reduces infarct size. Cardiovascular Research, 118(6), pp. 1535-1547. (doi: 10.1093/cvr/cvab204) (PMID:34132807)
McCarroll, C. S. et al. (2018) Runx1 deficiency protects against adverse cardiac remodeling after myocardial infarction. Circulation, 137(1), pp. 57-70. (doi: 10.1161/CIRCULATIONAHA.117.028911) (PMID:29030345) (PMCID:PMC5757664)
Elliott, E.B., Kelly, A., Smith, G.L. and Loughrey, C.M. (2012) Isolated rabbit working heart function during progressive inhibition of myocardial SERCA activity. Circulation Research, 110(12), pp. 1618-1627. (doi: 10.1161/CIRCRESAHA.111.262337)
Kelly, A., Elliott, E.B., Matsuda, R., Kaneko, N., Smith, G.L. and Loughrey, C.M. (2012) The effect of K201 on isolated working rabbit heart mechanical function during pharmacologically-induced Ca2+ overload. British Journal of Pharmacology, 165(4b), pp. 1068-1083. (doi: 10.1111/j.1476-5381.2011.01531.x)
Currie, S., Elliott, E.B., Smith, G.L. and Loughrey, C.M. (2011) Two candidates at the heart of dysfunction: The ryanodine receptor and calcium/calmodulin protein kinase II as potential targets for therapeutic intervention—An in vivo perspective. Pharmacology and Therapeutics, 131(2), pp. 204-220. (doi: 10.1016/j.pharmthera.2011.02.006)
Elliott, E.B., Hasumi, H., Otani, N., Matsuda, T., Matsuda, R., Kaneko, N., Smith, G.L. and Loughrey, C.M. (2011) K201 (JTV-519) alters the spatiotemporal properties of diastolic Ca2+ release and the associated diastolic contraction during β-adrenergic stimulation in rat ventricular cardiomyocytes. Basic Research in Cardiology, 106(6), pp. 1009-1022. (doi: 10.1007/s00395-011-0218-4)
Smith, G.L., Elliott, E.B., Kettlewell, S., Currie, S. and Quinn, F.R. (2006) Na+/Ca2+ Exchanger Expression and Function in a Rabbit Model of Myocardial Infarction. Journal of Cardiovascular Electrophysiology, 17(s1), S57-S63. (doi: 10.1111/j.1540-8167.2006.00384.x)
Teucher, N. et al. (2004) Excessive sarcoplasmic/endoplasmic reticulum Ca2+-ATPase expression causes increased sarcoplasmic reticulum Ca2+ uptake but decreases myocyte shortening. Circulation, 110(23), pp. 3553-3559. (doi: 10.1161/01.CIR.0000145161.48545.B3)
