Immunology 3A and 3B Course Information 2023-2024
Welcome to Year 3 of your programme. Courses at this level should be rewarding and enjoyable, but they require a clear commitment from you and your active participation and attendance.
We recommend that you read this Course Information Document at the start of Year 3.
In addition, there is important information about regulations, assessment and progression (including DD to Honours progression) in the Life Sciences Handbook: Regulations & Advice; again, you should read this document at the start of the year and you must refer to it as necessary.
Please keep this Course Information Document for future reference after you graduate; you may need to provide course details for further study or other training.
While the information contained in the document is correct at the time of printing, it may be necessary to make changes. Check your online timetable, Moodle and your email messages regularly.
Immunology 3A
Professor Robert Nibbs, Robert.Nibbs@glasgow.ac.uk
Deputy: Dr Georgia Perona-Wright, Georgia.Perona-Wright@glasgow.ac.uk
Immunology 3B
Professor Robert Nibbs, Robert.Nibbs@glasgow.ac.uk
Deputy: Professor Mariola Kurowska-Stolarska, Mariola.Kurowska-Stolarska@glasgow.ac.uk
Professor Simon Milling, Simon.Milling@glasgow.ac.uk
Deputy: Professor Robert Nibbs, Robert.Nibbs@glasgow.ac.uk
Teaching staff names can be found on your online timetable and contact details can be found on the University website Staff A-Z
Dr Janine Coombes, Robert Gordon University
The Life Sciences Office is located in Room 354 of the Sir James Black Building. Opening hours for enquiries are: Monday to Friday: 9:30am to 4:30pm.
Course Code
BIOL4056
Course Title
Immunology 3A
Academic Session
2023-24
Short Description of the Course
The course will provide students with an understanding of the immune system and practical experience in laboratory techniques that can be used to investigate it. The focus is on aspects of innate and acquired immunology; the two principal wings of the immune system.
Requirements of Entry
Normally, this course is only open to students admitted to Level-3 of a programme for which this is a compulsory course. The course may also be available to visiting students, at the discretion of the Life Sciences Study Abroad Coordinators.
Associated Programmes
This is a compulsory course for undergraduate programmes in Immunology.
Available to visiting students
Yes
Available to Erasmus students
Yes
Typically offered
Semester 1
Timetable
The course will consist of lectures, laboratories, tutorials and seminars as arranged. The timetable will vary from week to week to accommodate staff and resource availability, and to meet the educational needs of the course.
Course Aims
The course aims to provide an understanding of the cardinal systems of immuno-biology, drawing on experimental approaches at the molecular/genetic, cellular and tissue levels. The focus is on aspects of innate and acquired immunology; the two principal wings of the immune system.
Intended Learning Outcomes of Course
By the end of the course, students will be able to:
· explain the principal mechanisms that permit immune recognition of infection and injury;
· identify and describe the key cell types, their development and function within the immune system;
· appraise and contrast innate versus adaptive immune function;
· describe innate sensor activities appropriate to different pathogens;
· apply statistical methods to analyse experimental data;
· review and evaluate concepts/data from the field of immunology;
· solve problems of a numerical or logical nature as part of data analysis/comprehension tasks;
· demonstrate practical skills in the application of fundamental immunological techniques.
Minimum Requirements for Award of Credits
Students must submit at least 75% by weight of the components (including examinations) of the course’s summative assessment.
Description of Summative Assessment
The course will be assessed by a problem style examination (20%) in the December diet, an essay-based examination (40%) in the April / May diet and in-course assessment (40%).
In course assessment comprises four components. These are designed to test verbal/presentation skills (10%), essay writing (10%), laboratory skills (10%) and data comprehension and analysis in journal clubs using small groups with set exercises (10%).
Are reassessment opportunities normally available for all summative assessments in this course
Not applicable for Honours courses
Formative Assessment and Feedback
Formative assessment is provided informally by journal club tutors and lecturing staff.
Timetabled activities tied to formative assessment include:
· Presentation practice: feedback is provided by the class and staff at the time of the presentation.
· Essay practice: feedback is provided on preparative work for essays prior to their completion under exam conditions.
Examination Diet
December and April/May
Total Exam Duration
More than 180 mins
Course Code
BIOL4057
Course Title
Immunology 3B
Academic Session
2023-24
Short Description of the Course
This course provides a detailed insight into the mechanisms by which the immune system protects us from microbial pathogens, and how this knowledge is driving the development of novel vaccines, improved cancer therapies and new treatment strategies or autoimmune diseases such as rheumatoid arthritis and multiple sclerosis.
Requirements of Entry
Normally, this course is only open to students admitted to Level-3 of a programme for which this is a compulsory course. The course may also be available to visiting students, at the discretion of the Life Sciences Study Abroad Coordinators.
Associated Programmes
This is a compulsory course for undergraduate programmes in Immunology.
Available to visiting students
Yes
Available to Erasmus students
Yes
Typically offered
Semester 2
Timetable
The course will consist of lectures, laboratories, seminars and tutorials as arranged. The timetable will vary from week to week to accommodate staff and resource availability, and to meet the educational needs of the course.
Course Aims
The course aims to provide an understanding of the basic
principles of immune-recognition of pathogens, together with aspects of immune
dysfunction in the context of infection, autoimmunity and sterile inflammation.
Pathologic processes will be described in tissue specific contexts with a focus
on disease processes that are current topics of research in the Institute of
Infection, Immunity and Inflammation.
Intended Learning Outcomes of Course
By the end of this course, students will be able to:
· describe key aspects of immune system interactions with bacteria, fungi, parasites, viruses and cancers;
· identify and illustrate routes of microbial evasion of host immunity;
· describe basic mechanisms by which loss of self-tolerance leads to autoimmune diseases
· illustrate tissue-specific immunologic function and dysfunction (e.g. the lung, gut, joints, brain and skin);
· appraise the mechanistic basis of immune-based therapies for disease;
· design and organise oral presentations on key topics in immunology.
Minimum Requirements for Award of Credits
Students must submit at least 75% by weight of the components (including examinations) of the course’s summative assessment.
Description of Summative Assessment
The course will be assessed by a problem style examination paper (20%) in the April/May diet and an essay-based examination paper (40%) in the April / May diet and in-course assessment (40%).
In course assessment comprises four components. These are designed to test verbal/presentation skills (10%), essay writing (10%), laboratory skills (10%) and data comprehension and analysis in journal clubs using small groups with set exercises (10%).
Are reassessment opportunities normally available for all summative assessments in this course
Not applicable for Honours courses
Formative Assessment and Feedback
Formative assessment is provided informally by journal club tutors and lecturing staff.
Timetabled activities tied to formative assessment include:
· Presentation practice: feedback is provided by the class and staff.
· Essay practice: feedback is provided on essay preparation prior to essay completion under exam conditions.
Examination Diet
April/May
Total Exam Duration
More than 180 mins
Please check your online timetable for the most up to date version of your classes.
You should endeavour to attend lectures as it is not obligatory for staff to post their lecture material. Posted material will be found on the programme Moodle site. You should be aware that attendance at lectures may be monitored.
The laboratory and associated research skills sessions are designed to reinforce the knowledge gained from lectures and to develop your research and practical skills. These skills will be vital during your final year research project. You should keep a record of your results in a lab book. The laboratories and associated research skills sessions will be assessed by your submission of reports that are to be completed in your own time.
You are required to be present for the whole of each laboratory.
Throughout the session there will be tutorials that will examine particular themes recently covered by lectures. Please prepare for the tutorials by going through the relevant lecture/tutorial material. The tutorials are a compulsory part of the programme. If you are unable to attend you should inform the lecturer, in advance if possible.
The aim of these sessions is to develop your ability to critically appraise the primary scientific literature, discuss experimental techniques, and present and analyse the data. Research Fellows from the School of Infection & Immunity will convene these sessions and they form part of your summative assessment (details below).
In each component course there are sessions devoted to developing and assessing your oral presentation skills. The first is a practice session, but subsequent sessions are part of your summative assessment, as discussed below.
During the hours not scheduled for class activities, you should make abundant use of both the University Library and the Student Reading Rooms. Students are strongly advised to familiarise themselves with the relevant books and journals in these locations.
Get into the habit of reading scientific articles in journals. The Nature Reviews in Immunology and Trends in Immunology journals are particularly valuable, and you should aim to consult them regularly. Your lecturers will also cite review or research articles in their teaching sessions, and you might wish to access these articles to build your knowledge of certain topics.
The following textbooks will prove valuable for the course, and you may wish to purchase one. Make sure that you get the most up-to-date edition!
'Janeway's Immunobiology' by Murphy K & Weaver C.
‘Roitt’s Essential Immunology’ by Delves PJ, Martin SJ, Burton DR, Roitt IM.
‘Cellular and Molecular Immunology’ by Abbas AK, Lichtman AH, Pillai S.
‘Kuby’s Immunology’ by Kuby J, Kindt TJ, Osborne BA, Goldsby RA.
As a reminder of Level-2 Immunology, and an easy read introduction, you may also want to consider ‘How the Immune System Works’ by L Sompayrac
Other textbooks are available.
You will be awarded a separate grade for each of the two component courses which make up the Year 3 programme. Your result for each course is based on the items of assessment detailed below.
Note that the grades you obtain for Year 3 will contribute to your final degree grade and be used for writing references, for example for jobs or PhD places. They are also used as a guide to your ability if special circumstances affect your Year 4 result. It will also be one of the factors considered when allocating final-year projects and Honours options. Hence you should aim to get the best grade possible for both courses at the end of Year 3.
The relative weightings of the items of assessment for each course are:
|
Immunology 3A |
Immunology 3B |
End-of-course examination |
40% |
40% |
Problem paper examination |
20% |
20% |
Course
work: |
(40%): |
(40%): |
Total |
100% |
100% |
There are two essay-based examination papers in the April/May diet, one for Immunology 3A and one for Immunology 3B. These examination papers will contain essay titles and you will need to write and submit 3-4 essays.
There is a problem-style examination paper linked with each course. The first of these will be held in December at the end of your Immunology 3A course. In this exercise, you will be given a journal article at least a week in advance of the examination. The examination paper will contain several short answer questions based on the contents of the article (and the Supplementary Data associated with the article, if applicable) and interpretation of the data. The equivalent 3B problem examination paper will be held at the same time as the end-of-course examinations in April/May diet — it has the same format as the 3A problem paper.
Lab tests/reports, essays, oral presentations, and journal clubs all contribute equally to the assessed coursework component. The course work component contributes 40% of your final grade in each course.
Immunology 3A:
In 3A, laboratory and research skills will be assessed by two pieces of work to be completed in your own time and submitted for summative assessment by the specified deadline. The assignments include a data analysis and presentation task and a laboratory report, in which you will need to demonstrate an understanding of practical and analytical skills learned in a laboratory session. Details will be provided on Moodle and in the laboratory handbook.
Immunology 3B:
In 3B, laboratories and research skills will also be assessed by two pieces of work to be completed in your own time and submitted for summative assessment by the specified deadline. The first will be based on a Bioinformatics workshop. The second will require you to complete a report based on the Virtual Investigative Project that you will do in 3B. Details will be provided on Moodle and in the workshop handbook.
During the 3A course, you will be required to write a short summary of an immunological topic, and one essay. During the 3B course, you will be required to write one essay.
For the essays, you will be given a single essay title or topic or asked to select your favourite from several titles. You will then be expected to research and write the essay in your own time and submit it for summative assessment by the deadline date. When you are given the essay titles, you will also be provided with details of what format and length is expected. You will also be given some guidance about essay writing in teaching sessions in Immunology 3A. You must submit your essays online via Moodle. Glasgow University and the Immunology staff take plagiarism seriously. We will check submissions of electronic copies of most coursework using plagiarism software (Turnitin) and you might be asked to complete a declaration to confirm that the submitted work is original and all your own work.
There are compulsory Journal Club sessions in each of the 3A and 3B courses, one of which is an introductory session and five of which will be assessed (2 in 3A and 3 in 3B). Postdoctoral researchers or research fellows from the School of Infection & Immunity will deliver these sessions, and the programme coordinator (Prof Robert Nibbs) also moderates the assessment. Students will be introduced to a range of primary research papers. The methodologies used in the study, and the presentation and analysis of the data will be discussed, and students will be given the opportunity to discuss and evaluate the papers. By the end of the Journal Club series, students should be able to (i) analyse and evaluate experimental data, (ii) confidently discuss and critically appraise, primary scientific literature, and (iii) summarise complex findings in a succinct manner.
In advance of each Journal Club, instructions and scientific paper(s) will be emailed or posted on Moodle. You will be expected to read the research article and be ready to discuss the contents of the paper (methodologies, data, conclusions etc) in small groups and with the Journal Club organiser.
The first Journal Club session in Immunology 3A (referred to as the ‘Introduction & Advice’ session) will NOT form part of your summative assessment. It is designed to introduce the Journal Club scheme, provide information on what is expected from you, and describe how you will be assessed in subsequent Journal Clubs. If you are uncertain about what is expected from you in the Journal Clubs, or if it is unclear how you will be assessed, then it is up to you to ask the Journal Club organiser or the course coordinator.
The two subsequent Journal Clubs in Immunology 3A, and the three Journal Clubs in Immunology 3B, will form part of your summative assessment. Those in 3A are each worth 5% of your 3A grade, while those in 3B are each worth 3.33% of your 3B grade. It is important that you prepare well and contribute actively during the Journal Club, as this will likely be reflected in your grade. After each Journal Club, your grade, along with some feedback, will be posted on Moodle. You should reflect on the feedback and your performance, and attempt to build on what you have learnt so that you can improve your performance in subsequent sessions.
There are two compulsory Oral Presentation sessions each semester each worth 5% of your grade for the relevant course. You will be asked to prepare presentations on a variety of topics. There will be a chance to practice your Oral Presentation skills at SCENE in the Immunology 3A course - this will not form part of your summative assessment. At this session, you will: (i) give a short presentation (alone or as part of a pair); (ii) receive some feedback; and (iii) be given a summary of what you are expected to do at subsequent sessions and how your performance will be assessed. You should take this opportunity to ask questions and ensure you have a clear idea what is expected. At subsequent Oral Presentation sessions, staff will grade your work. Feedback will be given collectively to the class and/or on a one-to-one basis by the staff that listen to your presentations.
Date of Assessment / Deadline for hand-in |
Description of item of assessment |
Assessment worth |
Feedback Provided |
---|---|---|---|
4/10/2023 |
Practice Presentations |
- |
4-5/10/2023 |
16/10/2023 16:00 (Moodle Submission) |
Written Summary of Practice Presentation |
3% |
15/11/2023 |
23/10/2023 |
Journal Club 1 |
5% |
13/11/2023 |
30/10/2023 16:00 (Moodle Submission) |
Lab & Research Skills: Data Analysis and Presentation Task |
3% |
20/11/2023 |
02/11/2023 |
3A Presentation 1 |
5% |
23/11/2023 |
04/11/2023 09:00 (Moodle Submission) |
Optional: 3A Practice Problem Paper |
- |
27/11/2023 |
24/11/2023 |
Journal Club 2 |
5% |
15/12/2023 |
01/12/2023 |
3A Presentation 2 |
5% |
08/01/2024 |
18/12/2023 16:00 (Moodle Submission) |
Lab & Research Skills: QPCR Lab Report |
7% |
22/01/2024 |
05/01/2024 16:00 (Moodle Submission) |
3A Essay |
7% |
08/02/2024 |
Date of Assessment / Deadline for hand-in |
Items counting towards assessed coursework mark |
Assessment worth |
Feedback Provided |
---|---|---|---|
12/01/2024 |
Journal Club 3 |
5% |
02/02/2024 |
26/01/2024 |
3B Presentation 1 |
5% |
16/02/2023 |
12/02/2024 16:00 (Moodle Submission) |
Lab & Research Skills: Omics Lab report |
3% |
05/03/2024 |
19/02/2024 |
Journal Club 4 |
5% |
12/03/2024 |
04/03/2024 |
3B Presentation 2 |
5% |
25/03/2024 |
n/a |
Journal Club 5 |
n/a |
n/a |
20/03/2024 10:00 (Moodle Submission) |
Optional: 3B Practice Problem Paper |
- |
12/04/2024 |
22/03/2024 16:00 (Moodle Submission) |
Lab & Research Skills: VIP report and peer assessment |
7% |
19/04/2024 |
29/03/2024 16:00 (Moodle Submission) |
3B Essay |
10% |
19/04/2024 |
All information such as lecture notes will be made available via Moodle. Messages will be sent to the class through Moodle.
Relevant course information will be sent to your university student email account only. It is your responsibility to check your email regularly.
All students on the third year Immunology course are expected to progress to the Year 4 course (with or without completing an MSci Work Placement year). However, if you decide to graduate at the end of Year 3, it is suggested that you consult the Careers Service as early as possible in the year. Relevant career/job/studentship information received may also be circulated by email or posted on Moodle.
Constructive, detailed feedback from students is strongly encouraged and helps us to improve the course in future years. Students are therefore asked to complete feedback forms when requested. Professor Nibbs is also happy to hear student opinions of the Programme and its component courses and will try to sort out any problems that arise. If students feel that problems have not been satisfactorily resolved, they should contact Professor Olwyn Byron, Director of Education in the School of Infection and Immunity.
Some students may wish to explore the MSci with Work Placement programme run by the School of Life Sciences. Students on this programme spend a year between Level 3 and 4 working in an academic or industrial research lab, and graduate with an MSci degree rather than a BSc. Only the best students are selected for participation, and in recent years nearly one third of Immunology programme students go out on Work Placement. Anyone interested would be advised to look into this during their Level 2 studies. Prof Nibbs acts as mentor for Immunology students whilst they on Work Placement and can be contacted by anyone who is interested in the scheme.
Several research seminars are organised by the School of Infection and Immunity. Further information on these and other seminars is on the Level-3 Immunology Moodle page. These seminars provide very useful amplification of coursework, and you are strongly urged to attend. Extra credit is often given for the use of information derived from seminars in examination answers.
The five component courses which make up the final year of your programme are:
1 x project or dissertation course (40 credits)
1 x the core course for your programme (20 credits)
3 x Honours options (3 x 20-credits)
Semester |
Day |
Course block |
Suffix on Course Name |
1 |
Monday |
Core block |
"…4X core" |
1 |
Tuesday |
|
|
1 |
Wednesday |
|
|
1 |
Thursday |
|
|
1 |
Friday |
S1 option block |
"…4Y option" |
2 |
Monday |
S2-A option block |
"…4A option" |
2 |
Tuesday |
S2-B option block |
"…4B option" |
2 |
Wednesday |
S2-E option block |
"…4E option" |
2 |
Thursday |
S2-C option block |
"…4C option" |
2 |
Friday |
S2-D option block |
"…4D option" |
You should devote THREE days per week to the research phase of the project, normally all day Tuesday, Wednesday AM and all day Thursday during 10 weeks of Semester 1. The remaining half day can be undertaken Monday and/or Friday and/or Wednesday PM, depending on your own taught course timetable and the nature of your project.
There are two compulsory Immunology courses in Semester 1 and you take two Honours options in Semester 2.
The Semester 1 options are usually taught on Mondays and Fridays.
Semester 2 options are arranged in five blocks, one for each day of the week (4A, 4B, 4C, 4D and 4E options). You choose two options from these five blocks, but no more than one for any block.
Once enrolment opens in August, you choose the options that you wish to study in final year. Please note that the list of offered Honours options changes slightly each year as options are introduced, withdrawn or moved to a different block; therefore, options you see in your MyCampus My Requirements report may not be available for you to choose when you reach final year.
You do not have a free choice when choosing options. The following factors determine which options you can take.
Each programme specifies which options are compulsory and recommended for that programme. You must choose options which satisfy the stated Requirements for your programme.
In addition, each option specifies restrictions on admission (“Requirements of Entry” or “Enrolment Requirements”) to ensure that only students with the necessary academic background can enrol on that option. A few options allow any Life Sciences final-year student to enrol while other options only accept enrolment from students registered for a particular programme or set of programmes (for example Behavioural Ecology 4B option specifies the following: “Normally, only available to final-year Life Sciences students in the Animal Biology group programmes”).
A few options require you to apply in advance during Year 3. You cannot take one of these options if you have not been approved in advance. Currently, these are:
Tropical Marine Biology (with Field Course) 4Y option
Marine Mammal Biology (with Field Course) 4Y option
Ecology & Conservation of African Ecosystems (with Field Course) 4Y option
Investigating Biological Function 4B option
Most options limit the number of students that may enrol. For many options, the limit is around 30 students but some options have a lower or higher limit on class size. Enrolment is on a first-come, first-served basis.
An option may be cancelled if too few students wish to do it or if there are other circumstances which mean an option cannot run.
You undertake a piece of independent work in final year, either a project or a dissertation. University regulations stipulate that you MUST obtain at least D3 in the “independent work” course for an Honours degree to be awarded.
During Year 3, you choose which type of final-year project you would like to do. There are four types of project within the Life Sciences portfolio:
Investigative (both laboratory-based “wet” projects and traditional “dry” projects)
Dissertation
Outreach (both School and Public Engagement)
Internship *
* Although the Internship type of project is available in theory to students on any programme, this will depend on internships being offered which are suitable to the programme. Until now, internships have only been available to students in Physiology & Sports Science.
The type of project you are allocated determines which project course you enrol on in MyCampus.
It may not be possible to allocate projects in line with your aspirations but staff seek to maximise each student’s preference. Your grades from Year 3 may be taken into account when project allocations are being made.
If you are a student in the Animal Biology Group (Marine & Freshwater Biology or Zoology), you are encouraged to think up possible projects yourself. However, you must find a member of staff willing to act as your supervisor.
Please refer to the current session’s Project Course Information Document for more information.
The structure of the final-year curriculum is more complex than Year 3. Therefore, it is very important that you use the guidance in MyCampus My Requirements to enrol on appropriate courses. Read the information carefully and ensure than none of the sections on My Requirements are labelled “Not Satisfied”.