MRC Impact Acceleration Account (IAA) Award
The MRC Impact Acceleration Account (IAA) award is a strategic award aimed at accelerating the translation of discovery research towards impact, by supporting proof-of-concept studies, pump-priming and feasibility studies. IAA aims to accelerate development by providing locally administered, responsive and flexible funding to support preliminary translational work. Projects are required to align with at least one of the IAA core objectives.
Call open to researchers for:
- Development Projects up to £80k, to support the progression of an innovation along the translational pathway. Applicants will be asked to demonstrate how the IAA award would facilitate this and clearly identify the next steps in the translational pathway after completion of the IAA-funded work. Projects typically up to 12 months in duration.
- Partnership Projects up to £20k, to develop new academic and industry interactions and enable knowledge exchange, events, collaborative working and cross-sector skills flow as well as funds towards thematic partnering events and enterprise and/or industry secondments.
- Early concept projects up to £20k in value, to support translational projects at an early stage of development or to generate evidence to support a later stage translational award. These awards are intended to bridge the gap between discovery research and early-stage translation and are suitable for projects that are considered too early stage for a full IAA development award. Projects can be between 3-4 months in duration.
- Mobility Opportunities up to £10k, to support the flow of people & expertise between academia & external partners. Mobility awards are flexible - they can be short and focused or can be a component of a larger project. Secondments can also be part time. The IAA will cover the salary costs for university staff seconded to external organisations for the time spent with the host. IAA funds can also be used to fund travel and subsistence costs, as well as other resources required by the secondment project.
- IAA funds can also be used to support market assessment, development of business cases and access to external expertise.
Please note that there are institutional rules and processes relating to formal staff secondments which must be adhered with. In particular, the visa and immigration status of the proposed secondee must be considered. If you are unsure please contact your local HR Advisor for advice.
Application forms must be submitted via email to mvls-innovation@glasgow.ac.uk.
The main Development Grant Funding Application Form can be used for all 4 IAA objectives (including Partnership and Early Concept projects). However, if you are applying for an event only, or mobility only, please use the lighter touch application forms below.
Events, Engagement & Training Application Form
Mobility Fund Application Form
It is important that applicants can demonstrate how their project fits within the remit and provide a short background of their underpinning research, explaining how the funds requested can contribute towards the successful progression of their work with a focus on clear outcomes.
Applicants are strongly encouraged to reach out to the TRI and their local school IEE Director to discuss their project proposal prior to submission.
If within remit, multiple IAAs can be applied for from one application. For more information, access the drop-down menus below and read the full T&Cs. Please also watch our Applying for TRI Funding Video for advice on your application.
Contacts
- Dr Christopher Syme Translational Research Officer, SBOHVM, SII, SCS
- Dr Michaela Petaroudi Translational Research Officer, SCMH, SMDN, SMB
- Dr Stacy Robertson Translational Research Officer, SPN, SHW
- For general enquiries and non-MVLS applicants, contact mvls-innovation@glasgow.ac.uk
University of Glasgow IAA Core Objectives
- Capacity building, culture change and engagement
Provide flexible and fast support allowing commercial ideas to flourish, embedding responsible innovation and sustainability. Development and de-risking, proof of concept grants.
- Partnership development
Increase the volume and depth of our partnerships through greater stimulation of knowledge exchange, external engagement and relationship building.
- Commercialisation & entrepreneurship
Increase economic impact of UKRI-funded research, training, access to industry expertise as well as workshops and sandpits.
- Mobility
Supporting the flow of people & expertise between academia & external partners.
Project & Applicant Eligibility
This support scheme is focused on the translation of research towards impact. Fundamental or discovery research is out with remit.
It is important that applicants can demonstrate how their project fits within the remit and provide a short background of their underpinning research, explaining how the funds requested can contribute towards the successful progression of their work with a focus on clear outcomes.
Collaborations with external partners is encouraged, but not necessary for your funding application. Examples of eligible partners include private sector, government bodies, public sector organisations including the NHS, charities, NGOs and other third sector organisations. If such a collaboration is proposed in your applications, you must ensure that formal collaboration agreements are in place with any external partners before the beginning of your project. This can be included as a letter of support. The TRI recommend that you discuss this with your external partners or collaborators at an early stage of the proposal development and before applying for funding.
Principal investigators of IAA awards must be a University of Glasgow employee and have a staff number, as well as being contracted for the duration of the project. Early Career Researchers can apply for standard IAA funding as the principal investigator of a project. Written approval of their line manager will be required.
For secondment projects, all secondees must comply with visa and immigration requirements. Please check with the MVLS HR team prior to applying.
Application Criteria
Funding proposals must:
- describe the area of knowledge, including the underpinning research and the anticipated innovation to be developed;
- have a single, named PI who is responsible for the project, who must be a member of staff at the University of Glasgow;
- briefly outline the background research on which the proposed work is based on;
- describe the current stage of development and how it will be moved forward by the funding requested for the proposed IAA project;
- provide details on the existing needs for this work and the opportunities that will be addressed by this project. This can be backed up by evidence derived from the market, existing or identified stakeholders or any other impact drivers, where appropriate;
- outline the current barriers to impact;
- describe any competing technologies and the advantages of the proposed innovation;
- clearly present a budget breakdown per milestone, with timescales, including the value of contributions in-cash or in-kind from partners;
- describe the risks involved with each milestone and the mitigation plans in place to address these;
- provide details of anticipated project outcomes and impacts, including the way of achievement, anticipated timescales, and how the anticipated outcomes will be measured;
- demonstrate that all appropriate agreements and contracts are in place and an appropriate IP strategy is being considered or adopted (where applicable);
- state clear next steps, should the project be successful, along with potential benefits to the University of Glasgow;
- outline how responsible innovation, sustainability and Equality, Diversity and Inclusion (EDI) principals will be incorporated into your project.
IAA applications will be assessed by the TRI Management Review Panel and will consider the above criteria. Proposals that fail to address these criteria will be deemed ineligible for funding and may by rejected, or feedback given for resubmission. It is strongly encouraged that you discuss your proposal with the TRI management team before submitting your application.
Funded Projects & Case Studies
Please see links to case studies of some of the previously funded MRC IAA projects, and a full list of funded projects below, listed by parent award round.
- Nebu~Flow: Next Generation of Nebulisers for Efficient Respiratory Drug Delivery
- VascuSens: Self-Reporting Vascular Graft Development
- Portage Glasgow Ltd: University of Glasgow Partners with Portage Pharmaceuticals
- Mitotargin: Developing novel diagnostics and therapeutics targeting the mitochondria
- Disruptyx Therapeutics: Developing the next-generation of precision peptide therapeutics against cancer
MRC IAA Project Development |
|
2022 | |
Qammer Abbasi | Non-Invasive Glucose Level Monitoring System |
George Baillie | 5th Generation CAR-T Cell Therapy for Prostate Cancer |
Vignir Helgason | Clinical inhibitors of mitochondrial pyruvate carriers as therapeutics against AML |
Kevin Rattigan | Therapeutic enzyme to exploit tyrosine dependency in leukaemia |
John Mercer | VascuSens - Larif and Auto Calibrating Implants |
Kostas Tokatlidis | Mitotargin ADME |
Connor Blair | Optimisation of c-RAF inhibitor peptide for KRAS-driven pancreatic cancer |
Gang Li | Reducing VR motion sickness using a built-in neurostimulation module |
Ed Hutchinson | Virus Dashboards: Preparing for Pandemics |
James Brewer | Development of a novel class of vaccine adjuvants to industrial readiness |
2020 | |
Sheila Graham | BioMARSC: RNA Biomarker Matrix for Risk Stratification of Cervical Disease |
Kostas Tokatlidis | Mitotargin (and ADME Top Up) |
George Baillie | Charles River DMPK Services |
Andrew Roe | The anti-virulence compound aurodox: a pathway to translation - Follow On |
John Mercer | VascuSens Follow On |
Nigel Jamieson | AI-Pancreas - Integrating spatial multi-omics |
James Brewer | Market-led proof of concept data generation for vaccine adjuvant portfolio |
Jon Cooper | Antimicrobial peptides as designer drugs |
Connor Blair | Inhibiting c-Raf activity and treating pancreatic cancer – Follow on |
Dan Walker | A platform technology for engineering therapeutic protein antibiotics |
Qammer Abbasi | Non-Invasive Glucose Level Monitoring System |
Andrew Roe/Amy Cattanach | Identification of a unique metabolic signature associated with bacterial sepsis |
Tiziana Lembo | Empowering engagement for antimicrobial resistance policy change in Tanzania |
Jo Halliday | Human brucellosis policy in Tanzania: Evidence based update of clinical guidance |
George Baillie | 5th Generation CAR-T Cell Therapy for Prostate Cancer |
James Brewer/Amy Cattanach | Targeting the T cell/Dendritic cell synapse to treat inflammatory diseases. |
Vignir Helgason | Clinical inhibitors of mitochondrial pyruvate carriers as therapeutics against AML |
Kevin Rattigan | Therapeutic enzyme to exploit tyrosine dependency in leukaemia |
James Brewer | Development of a novel class of vaccine adjuvants to industrial readiness |
Shajan Gunamony | Developing a next generation RF Coil for neurovascular imaging with 7T MRI systems |
2019 | |
Jim Brewer | Image based screening of aptamer libraries for novel immunomodulators |
Andrew Tobin | Targeting the malaria protein kinase PfCLK3 |
Vignir Helgason | Combining TKI Treatment with Novel Autophagy Inhibitor (MRT403) for Eradication of Leukaemic Stem Cells |
Rick Maizels | Therapeutic application of a novel parasite-derived immunosuppressive protein |
Xu Huang, Wheadon, Jorgensen | Target validation of the critical epigenetic regulator, KDM4A in acute myeloid leukaemia |
Karen Keeshan | Developing TRIB2 as a predictive biomarker for acute myeloid leukaemia sensitivity to the clinical covalent multi-ERBB compounds |
Dan Walker | Inhaled Pyocins for the Treatment of P.A. Infection |
John Mercer | Smart Stent |
Kostas Tokatlidis | Mitotargin |
2018 | |
Graeme Milligan | Developing antagonists of the G protein coupled receptor GPR84 with improved drug-like properties |
Lilach Sheiner | Enhancing the pathway to commercialisation of a new potential anti-malaria and anti-toxoplasmosis family of compounds |
Elijah Nazarzadeh/Andrew Tobin | Novel Platform for Precision Pulmonary Delivery of High Value Therapeutics |
Ruth Zadoks/Julien Reboud | Translation of origami LAMP research into a novel point-of-care diagnostic for Group B Streptococcus |
Jose Penades/Victor Rodrigo Ibarra Chavez | Development of a novel biotechnology-derived antimicrobial approach for therapy and diagnostics using synthetic Phage-Inducible Chromosomal Islands |
Dan Walker | Identification, characterisation and engineering of highly specific protein antibiotics active against Vancomycin Resistant Enterococcus |
John Mercer/Nosrat Mirzai | Smart Stent |
George Baillie | Enhancing Mas:ETB receptor interaction: A novel therapeutic target promoting vascular health: implications in pulmonary arterial hypertension |
2017 | |
Jo Halliday | BACTOCAP: Sequence capture for multiple bacterial zoonoses of international health importance |
Carl Goodyear | Epigenetic stratification of rheumatoid arthritis patients for response to biological Disease Modifying anti-Rheumatic Drugs |
David Robertson | GLUE: a software framework for hepatitis C virus genotyping / drug-resistance detection in a clinical setting |
Michael Barrett | The Tryp Chip |
Susanna Cooke | Validation of a sequence capture assay for homologous recombination deficiency in pancreatic cancer Need and rationale |
2016 | |
Dan Walker/Gerasimidis Konstantios | Precision engineering of the human gut microbiome |
Rhian Touyz | Enhancing Mas:ETB receptor interaction: A novel therapeutic modality for pulmonary hypertension. |
Lee Cronin | Time-modulated programmable multi-drug treatment for the suppression and reversal of antibiotic resistance |
Carl Goodyear/Nikolaj Gadegaard | Translation of nanotechnology for improved bone regeneration |
Carl Goodyear/Nikolaj Gadegaard | Prognostic biomarkers in rheumatoid arthritis |
Keith Muir/Rhian Touyz | Validating molecular targets in the vascular pathophysiology of CADASIL |
George Baillie | Targeting the PKD1-HSP20 axis in heart disease |
MRC IAA Partnership Development |
|
2020 | |
George Baillie | Biotheryx Collaboration |
Donal Wall | Glasgow University Microbiome Initiative (GUMI) inaugural symposium |
Ronan Daly | Polyomics Affinity Biomarkers |
Katie Robb | Screening Action Model (I-SAM) to improve cancer screening access - Market and Commercial Assessment |
Kirstin Mitchell | Software tool to assess outcomes of sex therapy: market viability |
Sandosh Padmanabhan | Industry led cross-college digital health innovation opportunity events |
2018 | |
George Baillie | Portage Glasgow Ltd |
Neil Hawkins | Health Economics for Precision Medicine |
Lilach Sheiner | FutuRX |
Julian Dow/Shireen Davies | Market research - Kidney nephrotoxicity |
Eric Kalkman | Autophagy Conference |
Craig Daly | Market research |
Maria McPhillips | CVR Industry Workshop |
Andrew Tobin/Sarah Hesse | Assessing the effect of targeting the M1 muscarinic receptor in a mouse model of Alzheimer’s disease |
Jim Brewer | Road-mapping for image-based screening |
Ruth McLaughlin | Health Innovation Hub |
Shajan Gunamony/David Porter | Enabling specialist coil design to facilitate advanced imaging using 7T MRI |
Kostas Tokatlidis | Market research for commercial development of a novel peptide tool for external payload delivery to mitochondria in cells |
George Baillie | BioTheryX |
Jane Townson/Jo Edwards/Gerard Lynch | Enhanced project management support for integrated diagnostics |
George Baillie | Enhancing Mas:ETB receptor interaction |
2017 | |
George Baillie | Developing a joint venture with Portage Pharmaceuticals Ltd (PPL): staff visit/exchange |
Ruth McLaughlin | Discovery Science Surgeries |
Lilach Scheiner | Validation of ATrx2 as a tractable anti-malarial target to enable drug discovery work |
Carolyn Low | Sequencing Consortium |
Sara Macdonald | HW - public patient interaction |
2016 | |
James Brewer | Developing a strategic relationship with GSK in adjuvant evaluation and mechanism of action. |
Gerard Graham | Basic Science Surgeries |
Tomoko Iwata | Exploration of Perkin-Elmer Quantitative Pathology Imaging (QPI) for clinical diagnosis |
Caroline Woodside | Industry Day: Future of Biomedicine 27th September 2015 |
Rhian Touyz | Histoindex-Clinnovate Health UK |